An ATP-dependent translocase ABCB1b that is encoded in the genome of mouse. [PRO:DAN, UniProtKB:P06795]
ATP-binding cassette sub-family B member 1B;
Multidrug resistance protein 1B;
7.6.2.2;
P-glycoprotein 1;
Phospholipid transporter ABCB1;
7.6.2.1
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| amiodarone | Mus musculus (house mouse) | Ki | 12.7000 | 1 | 1 |
| astemizole | Mus musculus (house mouse) | IC50 | 1.7000 | 2 | 2 |
| verapamil | Mus musculus (house mouse) | IC50 | 2.0000 | 2 | 2 |
| cimetidine | Mus musculus (house mouse) | IC50 | 50.0000 | 2 | 2 |
| clotrimazole | Mus musculus (house mouse) | IC50 | 3.5000 | 2 | 2 |
| clotrimazole | Mus musculus (house mouse) | Ki | 25.1000 | 1 | 1 |
| fluconazole | Mus musculus (house mouse) | Ki | 1,000.0000 | 1 | 1 |
| itraconazole | Mus musculus (house mouse) | IC50 | 0.7000 | 2 | 2 |
| ketoconazole | Mus musculus (house mouse) | IC50 | 6.7000 | 2 | 2 |
| ketoconazole | Mus musculus (house mouse) | Ki | 6.9300 | 1 | 1 |
| miconazole | Mus musculus (house mouse) | IC50 | 2.0000 | 2 | 2 |
| miconazole | Mus musculus (house mouse) | Ki | 98.4000 | 1 | 1 |
| midazolam | Mus musculus (house mouse) | IC50 | 33.0000 | 2 | 2 |
| nicardipine | Mus musculus (house mouse) | IC50 | 8.0000 | 2 | 2 |
| ranitidine | Mus musculus (house mouse) | IC50 | 50.0000 | 2 | 2 |
| terfenadine | Mus musculus (house mouse) | IC50 | 2.0000 | 2 | 2 |
| reserpine | Mus musculus (house mouse) | Ki | 17.9000 | 1 | 1 |
| colchicine | Mus musculus (house mouse) | IC50 | 50.0000 | 2 | 2 |
| ergotamine | Mus musculus (house mouse) | Ki | 18.0000 | 1 | 1 |
| dihydroergotamine | Mus musculus (house mouse) | Ki | 1,000.0000 | 1 | 1 |
| erythromycin | Mus musculus (house mouse) | IC50 | 35.0000 | 2 | 2 |
| erythromycin | Mus musculus (house mouse) | Ki | 1,000.0000 | 1 | 1 |
| vinblastine | Mus musculus (house mouse) | IC50 | 8.0000 | 2 | 2 |
| pimozide | Mus musculus (house mouse) | IC50 | 50.0000 | 2 | 2 |
| bromocriptine | Mus musculus (house mouse) | Ki | 6.3900 | 1 | 1 |
| ergocristine | Mus musculus (house mouse) | Ki | 15.3000 | 1 | 1 |
| etoposide | Mus musculus (house mouse) | IC50 | 50.0000 | 2 | 2 |
| mibefradil | Mus musculus (house mouse) | IC50 | 10.0000 | 2 | 2 |
| ergocornine | Mus musculus (house mouse) | Ki | 19.1000 | 1 | 1 |
| dihydroergocristine | Mus musculus (house mouse) | Ki | 166.7000 | 1 | 1 |
| dihydroergocryptine | Mus musculus (house mouse) | Ki | 159.9000 | 1 | 1 |
| alpha-ergocryptine | Mus musculus (house mouse) | Ki | 26.9000 | 1 | 1 |
| tariquidar | Mus musculus (house mouse) | IC50 | 0.0643 | 1 | 2 |
| troleandomycin | Mus musculus (house mouse) | Ki | 1,000.0000 | 1 | 1 |
| ritonavir | Mus musculus (house mouse) | IC50 | 50.0000 | 2 | 2 |
| quinidine | Mus musculus (house mouse) | IC50 | 10.0000 | 2 | 2 |
| saquinavir | Mus musculus (house mouse) | IC50 | 50.0000 | 2 | 2 |
| ergonovine | Mus musculus (house mouse) | Ki | 1,000.0000 | 1 | 1 |
| digoxin | Mus musculus (house mouse) | IC50 | 50.0000 | 2 | 2 |
| biricodar | Mus musculus (house mouse) | IC50 | 5.0000 | 1 | 1 |
| cyclosporine | Mus musculus (house mouse) | IC50 | 0.7000 | 2 | 2 |
| cyclosporine | Mus musculus (house mouse) | Ki | 3.5000 | 1 | 1 |
| morphine | Mus musculus (house mouse) | IC50 | 50.0000 | 2 | 2 |
| xr 9577 | Mus musculus (house mouse) | IC50 | 0.3181 | 1 | 2 |