Proteins > Solute carrier family 22 member 1
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Solute carrier family 22 member 1
A solute carrier family 22 member 1 that is encoded in the genome of rat. [OMA:Q63089, PRO:DNx]
Synonyms
Organic cation transporter 1;
rOCT1
Research
Bioassay Publications (19)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (42.11) | 18.2507 |
| 2000's | 11 (57.89) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (42)
Drugs with Inhibition Measurements
Drugs with Other Measurements
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.Pharmaceutical research, , Volume: 18, Issue:11, 2001
Ventricular choline transport: a role for organic cation transporter 2 expressed in choroid plexus.The Journal of biological chemistry, , Nov-09, Volume: 276, Issue:45, 2001
Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.Biochimica et biophysica acta, , Mar-04, Volume: 1417, Issue:2, 1999
Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate.Molecular pharmacology, , Volume: 56, Issue:6, 1999
Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.The Journal of biological chemistry, , Dec-20, Volume: 271, Issue:51, 1996
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.Pharmaceutical research, , Volume: 18, Issue:11, 2001
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Selective substrates for non-neuronal monoamine transporters.Molecular pharmacology, , Volume: 56, Issue:1, 1999
Monoamine neurotransmitter transport mediated by the polyspecific cation transporter rOCT1.FEBS letters, , Oct-21, Volume: 395, Issue:2-3, 1996
Molecular mechanisms of organic cation transport in OCT2-expressing Xenopus oocytes.Biochimica et biophysica acta, , Mar-04, Volume: 1417, Issue:2, 1999
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.The Journal of pharmacology and experimental therapeutics, , Volume: 287, Issue:2, 1998
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Drug excretion mediated by a new prototype of polyspecific transporter.Nature, , Dec-08, Volume: 372, Issue:6506, 1994
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.The Journal of pharmacology and experimental therapeutics, , Volume: 287, Issue:2, 1998
Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney.Drug metabolism and disposition: the biological fate of chemicals, , Volume: 33, Issue:4, 2005
The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules.The Journal of pharmacology and experimental therapeutics, , Volume: 303, Issue:3, 2002
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.Pharmaceutical research, , Volume: 18, Issue:11, 2001
Drug excretion mediated by a new prototype of polyspecific transporter.Nature, , Dec-08, Volume: 372, Issue:6506, 1994
Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1).The Journal of pharmacology and experimental therapeutics, , Volume: 292, Issue:3, 2000
Role of organic cation transporters in the renal secretion of nucleosides.Biochemical pharmacology, , Jul-15, Volume: 60, Issue:2, 2000
Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate.Molecular pharmacology, , Volume: 56, Issue:6, 1999
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.The Journal of pharmacology and experimental therapeutics, , Volume: 287, Issue:2, 1998
Cloning and functional characterization of a rat renal organic cation transporter isoform (rOCT1A).The Journal of biological chemistry, , Jun-27, Volume: 272, Issue:26, 1997
Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.The Journal of biological chemistry, , Dec-20, Volume: 271, Issue:51, 1996
Drug excretion mediated by a new prototype of polyspecific transporter.Nature, , Dec-08, Volume: 372, Issue:6506, 1994
Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney.Drug metabolism and disposition: the biological fate of chemicals, , Volume: 33, Issue:4, 2005
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Drug excretion mediated by a new prototype of polyspecific transporter.Nature, , Dec-08, Volume: 372, Issue:6506, 1994
Transport of small organic cations in the rat liver. The role of the organic cation transporter OCT1.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 354, Issue:3
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.Pharmaceutical research, , Volume: 18, Issue:11, 2001
Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1).The Journal of pharmacology and experimental therapeutics, , Volume: 292, Issue:3, 2000
Drug excretion mediated by a new prototype of polyspecific transporter.Nature, , Dec-08, Volume: 372, Issue:6506, 1994
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.Pharmaceutical research, , Volume: 18, Issue:11, 2001
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1).The Journal of pharmacology and experimental therapeutics, , Volume: 292, Issue:3, 2000
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.Pharmaceutical research, , Volume: 18, Issue:11, 2001
Kinetic and selectivity differences between rodent, rabbit, and human organic cation transporters (OCT1).The Journal of pharmacology and experimental therapeutics, , Volume: 292, Issue:3, 2000
Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate.Molecular pharmacology, , Volume: 56, Issue:6, 1999
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.Pharmaceutical research, , Volume: 18, Issue:11, 2001
Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate.Molecular pharmacology, , Volume: 56, Issue:6, 1999
Drug excretion mediated by a new prototype of polyspecific transporter.Nature, , Dec-08, Volume: 372, Issue:6506, 1994
Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate.Molecular pharmacology, , Volume: 56, Issue:6, 1999
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.The Journal of pharmacology and experimental therapeutics, , Volume: 287, Issue:2, 1998
Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.The Journal of biological chemistry, , Dec-20, Volume: 271, Issue:51, 1996
Drug excretion mediated by a new prototype of polyspecific transporter.Nature, , Dec-08, Volume: 372, Issue:6506, 1994
Transport of small organic cations in the rat liver. The role of the organic cation transporter OCT1.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 354, Issue:3
Selectivity of the polyspecific cation transporter rOCT1 is changed by mutation of aspartate 475 to glutamate.Molecular pharmacology, , Volume: 56, Issue:6, 1999
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.The Journal of pharmacology and experimental therapeutics, , Volume: 287, Issue:2, 1998
Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.The Journal of biological chemistry, , Dec-20, Volume: 271, Issue:51, 1996
Drug excretion mediated by a new prototype of polyspecific transporter.Nature, , Dec-08, Volume: 372, Issue:6506, 1994
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Drug excretion mediated by a new prototype of polyspecific transporter.Nature, , Dec-08, Volume: 372, Issue:6506, 1994
Transport of small organic cations in the rat liver. The role of the organic cation transporter OCT1.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 354, Issue:3
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.The Journal of pharmacology and experimental therapeutics, , Volume: 287, Issue:2, 1998
Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.The Journal of biological chemistry, , Dec-20, Volume: 271, Issue:51, 1996
Transport of small organic cations in the rat liver. The role of the organic cation transporter OCT1.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 354, Issue:3
Renal organic cation and nucleoside transport.Biochemical pharmacology, , Jul-15, Volume: 64, Issue:2, 2002
Role of organic cation transporters in the renal secretion of nucleosides.Biochemical pharmacology, , Jul-15, Volume: 60, Issue:2, 2000
The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules.The Journal of pharmacology and experimental therapeutics, , Volume: 303, Issue:3, 2002
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.The Journal of biological chemistry, , Dec-20, Volume: 271, Issue:51, 1996
Drug excretion mediated by a new prototype of polyspecific transporter.Nature, , Dec-08, Volume: 372, Issue:6506, 1994
Transport of small organic cations in the rat liver. The role of the organic cation transporter OCT1.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 354, Issue:3
The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules.The Journal of pharmacology and experimental therapeutics, , Volume: 303, Issue:3, 2002
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.American journal of physiology. Renal physiology, , Volume: 281, Issue:3, 2001
Drug excretion mediated by a new prototype of polyspecific transporter.Nature, , Dec-08, Volume: 372, Issue:6506, 1994
Transport of small organic cations in the rat liver. The role of the organic cation transporter OCT1.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 354, Issue:3