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dapsone and Sensitivity and Specificity

dapsone has been researched along with Sensitivity and Specificity in 16 studies

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
" leprae to dapsone based on the folP1 drug resistance determining region (DRDR), rifampin (rpoB DRDR) and ofloxacin (gyrA DRDR) was evaluated using 211 clinical specimens from leprosy patients, including 156 multibacillary (MB) and 55 paucibacillary (PB) cases."3.85qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients. ( Araujo, S; Fontes, AB; Goulart, IMB; Goulart, LR; Li, W; Matsuoka, M; Rosa, PS; Scollard, DM; Suffys, P; Truman, RW; Vissa, V; Williams, DL, 2017)
"Currently recommended control measures for treating leprosy with multidrug therapy should control the spread of drug-resistant strains; however, dapsone (DDS) resistance continues to be reported."3.71Simultaneous detection of Mycobacterium leprae and its susceptibility to dapsone using DNA heteroduplex analysis. ( Gillis, TP; Kashiwabara, Y; Matsuoka, M; Pittman, TL; Williams, DL, 2001)
"Dapsone intermediates were characterized by mass spectrometry."1.51Dapsone- and nitroso dapsone-specific activation of T cells from hypersensitive patients expressing the risk allele HLA-B*13:01. ( Alhilali, K; Almutairi, M; Alzahrani, A; Amjad, J; Gibson, A; Kevin Park, B; Liu, H; Liu, J; Meng, X; Naisbitt, DJ; Ogese, MO; Ostrov, DA; Sun, L; Sun, Y; Zhang, F; Zhang, H; Zhao, Q, 2019)
"PCR sensitivity and specificity were 100 and 86."1.32Detection of Pneumocystis carinii and characterization of mutations associated with sulfa resistance in bronchoalveolar lavage samples from human immunodeficiency virus-infected subjects. ( Carrera, P; Lazzarin, A; Scarpellini, P; Zingale, A, 2003)
"Acetyl acetone is introduced as a new coupling agent for the spectrophotometric determination of some chemotherapeutic agents, such as metoclopramide, dapsone, p-aminobenzoic acid, and cisapride in both pure and dosage forms."1.31Spectrophotometric determination of some chemotherapeutic agents using acetyl acetone. ( Manju, B; Revanasiddappa, HD, 2002)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's3 (18.75)18.2507
2000's7 (43.75)29.6817
2010's4 (25.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Johnson, JD1
Dennull, RA1
Gerena, L1
Lopez-Sanchez, M1
Roncal, NE1
Waters, NC1
You, J1
Sun, L2
Zhao, Q2
Zhang, H2
Huai, P1
Yu, G1
Wang, Z1
Mi, Z1
Pang, Z1
Liu, H2
Zhang, F2
Araujo, S1
Goulart, LR1
Truman, RW1
Goulart, IMB1
Vissa, V1
Li, W1
Matsuoka, M2
Suffys, P1
Fontes, AB1
Rosa, PS1
Scollard, DM1
Williams, DL3
Alhilali, K1
Alzahrani, A1
Almutairi, M1
Amjad, J1
Sun, Y1
Meng, X1
Gibson, A1
Ogese, MO1
Kevin Park, B1
Liu, J1
Ostrov, DA1
Naisbitt, DJ1
Rochford, R1
Ohrt, C1
Baresel, PC1
Campo, B1
Sampath, A1
Magill, AJ1
Tekwani, BL1
Walker, LA1
Liu, Y1
Li, X1
Yang, C1
Tai, S1
Zhang, X1
Liu, G1
Zingale, A1
Carrera, P1
Lazzarin, A1
Scarpellini, P1
Martin, LK1
Murrell, DF1
Singh, HB1
Katoch, K1
Natrajan, M1
Sharma, RK1
Gupta, UD1
Sharma, VD1
Singh, D1
Chauhan, DS1
Srivastava, K1
Katoch, VM1
Pittman, TL1
Gillis, TP2
Kashiwabara, Y1
Kublin, JG1
Dzinjalamala, FK1
Kamwendo, DD1
Malkin, EM1
Cortese, JF1
Martino, LM1
Mukadam, RA1
Rogerson, SJ1
Lescano, AG1
Molyneux, ME1
Winstanley, PA1
Chimpeni, P1
Taylor, TE1
Plowe, CV1
Kwadijk, S1
ToraƱo, JS1
Revanasiddappa, HD1
Manju, B1
Fiallo, P1
Job, CK1
Gelber, RH1
Hill, C1
Izumi, S1
Freedberg, KA1
Tosteson, AN1
Cohen, CJ1
Cotton, DJ1
Nagelkerke, NJ1
Fidler, V1
Buwalda, M1

Trials

1 trial available for dapsone and Sensitivity and Specificity

ArticleYear
Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malaria.
    The Journal of infectious diseases, 2002, Feb-01, Volume: 185, Issue:3

    Topics: Antimalarials; Biomarkers; Child; Child, Preschool; Dapsone; Dihydropteroate Synthase; Double-Blind

2002

Other Studies

15 other studies available for dapsone and Sensitivity and Specificity

ArticleYear
Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Animals; Antimalarials; Benzothiazoles; Diamines; Drug Evaluation, Preclinical; Erythrocytes; Fluore

2007
Dynamic cytokine profiles combined with enzyme-linked immunospot assay are useful for immunologically confirming the dapsone hypersensitivity syndrome.
    Journal of the American Academy of Dermatology, 2021, Volume: 84, Issue:3

    Topics: Adult; Biomarkers; Cytokines; Dapsone; Diagnosis, Differential; Drug Hypersensitivity Syndrome; Enzy

2021
qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:6

    Topics: Bacterial Proteins; Dapsone; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Leprostatic Agents;

2017
Dapsone- and nitroso dapsone-specific activation of T cells from hypersensitive patients expressing the risk allele HLA-B*13:01.
    Allergy, 2019, Volume: 74, Issue:8

    Topics: Adult; Cross Reactions; Dapsone; Female; Gene Expression; HLA-B Antigens; Humans; Hypersensitivity;

2019
Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Oct-22, Volume: 110, Issue:43

    Topics: Aminoquinolines; Anemia, Hemolytic; Animals; Antimalarials; Chloroquine; Combined Modality Therapy;

2013
UPLC-MS-MS method for simultaneous determination of caffeine, tolbutamide, metoprolol, and dapsone in rat plasma and its application to cytochrome P450 activity study in rats.
    Journal of chromatographic science, 2013, Volume: 51, Issue:1

    Topics: Animals; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dapsone; Dr

2013
Detection of Pneumocystis carinii and characterization of mutations associated with sulfa resistance in bronchoalveolar lavage samples from human immunodeficiency virus-infected subjects.
    Journal of clinical microbiology, 2003, Volume: 41, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Bronchoalveolar Lavage Fluid; Dapsone;

2003
Treatment of pemphigus: the need for more evidence.
    Archives of dermatology, 2008, Volume: 144, Issue:1

    Topics: Dapsone; Drug Therapy, Combination; Humans; Needs Assessment; Pemphigus; Prednisone; Prognosis; Rand

2008
Effect of treatment on PCR positivity in multibacillary leprosy patients treated with conventional and newer drugs ofloxacin and minocycline.
    Acta leprologica, 1999, Volume: 11, Issue:4

    Topics: Adenosine Triphosphate; Biopsy; Clofazimine; Dapsone; DNA, Bacterial; Drug Evaluation; Drug Therapy,

1999
Simultaneous detection of Mycobacterium leprae and its susceptibility to dapsone using DNA heteroduplex analysis.
    Journal of clinical microbiology, 2001, Volume: 39, Issue:6

    Topics: Base Sequence; Dapsone; DNA, Bacterial; Drug Resistance, Microbial; Heteroduplex Analysis; Humans; L

2001
High-performance liquid chromatographic method with ultraviolet detection for the determination of dapsone and its hydroxylated metabolite in human plasma.
    Biomedical chromatography : BMC, 2002, Volume: 16, Issue:3

    Topics: Calibration; Chromatography, High Pressure Liquid; Dapsone; Humans; Hydroxylation; Leprostatic Agent

2002
Spectrophotometric determination of some chemotherapeutic agents using acetyl acetone.
    Drug development and industrial pharmacy, 2002, Volume: 28, Issue:5

    Topics: 4-Aminobenzoic Acid; Cisapride; Dapsone; Excipients; Hydrogen-Ion Concentration; Indicators and Reag

2002
Detection of Mycobacterium leprae and the potential for monitoring antileprosy drug therapy directly from skin biopsies by PCR.
    Molecular and cellular probes, 1992, Volume: 6, Issue:5

    Topics: Anti-Bacterial Agents; Biopsy; Clofazimine; Dapsone; DNA Probes; DNA, Bacterial; Drug Therapy, Combi

1992
Primary prophylaxis for Pneumocystis carinii pneumonia in HIV-infected people with CD4 counts below 200/mm3: a cost-effectiveness analysis.
    Journal of acquired immune deficiency syndromes, 1991, Volume: 4, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Aerosols; Antiviral Agents; CD4-Positive T-Lymphocytes; Cost-Ben

1991
Instrumental variables in the evaluation of diagnostic test procedures when the true disease state is unknown.
    Statistics in medicine, 1988, Volume: 7, Issue:7

    Topics: Dapsone; Enzyme-Linked Immunosorbent Assay; Hemagglutination Tests; Humans; Leprosy; Patient Complia

1988