Page last updated: 2024-08-07 18:43:33
Nischarin
A nischarin that is encoded in the genome of rat. [OMA:Q4G017, PRO:DNx]
Synonyms
Imidazoline receptor 1;
I-1;
IR1;
Imidazoline-1 receptor;
I1R
Research
Bioassay Publications (7)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (11)
Drugs with Inhibition Measurements
New imidazoline/α(2)-adrenoceptors affecting compounds-4(5)-(2-aminoethyl)imidazoline (dihydrohistamine) derivatives. Synthesis and receptor affinity studies.Bioorganic & medicinal chemistry, , Jan-01, Volume: 19, Issue:1, 2011
New analogues of agmatine with higher affinity to imidazoline receptors.Bioorganic & medicinal chemistry letters, , Feb-01, Volume: 19, Issue:3, 2009
A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin.Bioorganic & medicinal chemistry, , 07-15, Volume: 24, Issue:14, 2016
Synthesis and biological evaluation of 2-aryliminopyrrolidines as selective ligands for I1 imidazoline receptors: discovery of new sympatho-inhibitory hypotensive agents with potential beneficial effects in metabolic syndrome.Journal of medicinal chemistry, , Jan-22, Volume: 58, Issue:2, 2015
Methylation of imidazoline related compounds leads to loss of α₂-adrenoceptor affinity. Synthesis and biological evaluation of selective I₁ imidazoline receptor ligands.Bioorganic & medicinal chemistry, , Aug-01, Volume: 20, Issue:15, 2012
New imidazoline/α(2)-adrenoceptors affecting compounds-4(5)-(2-aminoethyl)imidazoline (dihydrohistamine) derivatives. Synthesis and receptor affinity studies.Bioorganic & medicinal chemistry, , Jan-01, Volume: 19, Issue:1, 2011
New analogues of agmatine with higher affinity to imidazoline receptors.Bioorganic & medicinal chemistry letters, , Feb-01, Volume: 19, Issue:3, 2009
A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin.Bioorganic & medicinal chemistry, , 07-15, Volume: 24, Issue:14, 2016
Synthesis and biological evaluation of 2-aryliminopyrrolidines as selective ligands for I1 imidazoline receptors: discovery of new sympatho-inhibitory hypotensive agents with potential beneficial effects in metabolic syndrome.Journal of medicinal chemistry, , Jan-22, Volume: 58, Issue:2, 2015
Methylation of imidazoline related compounds leads to loss of α₂-adrenoceptor affinity. Synthesis and biological evaluation of selective I₁ imidazoline receptor ligands.Bioorganic & medicinal chemistry, , Aug-01, Volume: 20, Issue:15, 2012
A combined ligand- and structure-based approach for the identification of rilmenidine-derived compounds which synergize the antitumor effects of doxorubicin.Bioorganic & medicinal chemistry, , 07-15, Volume: 24, Issue:14, 2016
[no title available]ACS medicinal chemistry letters, , Oct-13, Volume: 7, Issue:10, 2016