Page last updated: 2024-10-29

iofetamine and Sensitivity and Specificity

iofetamine has been researched along with Sensitivity and Specificity in 42 studies

Iofetamine: An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
" CNS lupus is indicative of advancing primary disease and is treated by steroid pulse therapy or increased dosage of steroids."1.34Evaluation of cerebral perfusion in patients with neuropsychiatric systemic lupus erythematosus using 123I-IMP SPECT. ( Kato, K; Seino, O; Shishido, F; Watanabe, H; Yoshida, A, 2007)
"Twenty-three patients with probable Alzheimer's disease, 22 patients with mild cognitive impairment who eventually developed Alzheimer's disease, eight patients with mild cognitive impairment who did not develop dementia, and 19 cognitively normal subjects were included in the study."1.31Combined Analysis of CSF Tau Levels and [(123)I]Iodoamphetamine SPECT in Mild Cognitive Impairment: Implications for a Novel Predictor of Alzheimer's Disease. ( Arai, H; Chiba, H; Higuchi, M; Hirai, H; Itoh, M; Maruyama, M; Matsui, T; Okamura, N; Sasaki, H; Seki, T; Tanji, H, 2002)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.38)18.7374
1990's12 (28.57)18.2507
2000's25 (59.52)29.6817
2010's3 (7.14)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
Hamaguchi, T1
Sanjo, N1
Ae, R1
Nakamura, Y1
Sakai, K1
Takao, M1
Murayama, S1
Iwasaki, Y1
Satoh, K1
Murai, H1
Harada, M1
Tsukamoto, T1
Mizusawa, H1
Yamada, M1
Hirooka, R1
Ogasawara, K2
Inoue, T1
Fujiwara, S2
Sasaki, M3
Chida, K2
Ishigaki, D1
Kobayashi, M2
Nishimoto, H1
Otawara, Y1
Tsushima, E1
Ogawa, A2
Yoshimura, M1
Kanesaka, N1
Saito, K1
Koizumi, K2
Tokuuye, K1
Goto, H1
Kuroda, H1
Suzuki, T2
Aso, K1
Yoshida, K1
Terasaki, K1
Kubo, Y1
Sathekge, M1
Maes, A1
D'Asseler, Y1
Vorster, M1
Van de Wiele, C1
Ushijima, Y2
Okuyama, C2
Mori, S1
Nakamura, T1
Kubota, T3
Nishimura, T3
Zaidi, H1
Montandon, ML1
Imaizumi, M2
Kitagawa, K2
Hashikawa, K1
Oku, N2
Teratani, T1
Takasawa, M2
Yoshikawa, T1
Rishu, P1
Ohtsuki, T1
Hori, M2
Matsumoto, M1
Inoue, K5
Ito, H6
Nakagawa, M1
Goto, R5
Yamazaki, T1
Fukuda, H5
Arbab, AS1
Aoki, S1
Toyama, K1
Araki, T1
Miyazawa, N1
Kumagai, H1
Umeda, T1
Arai, T1
Okubo, T1
Kabasawa, H1
Takahashi, Y1
Nishizawa, S1
Iida, H3
Tsuchida, T1
Konishi, J1
Yonekura, Y1
Sakai, T1
Kuzuhara, S1
Mizumura, S1
Kumita, S1
Cho, K2
Ishihara, M1
Nakajo, H1
Toba, M1
Kumazaki, T1
Kobayashi, H2
Watanabe, H2
Seino, T1
Suzuki, S1
Sato, Y1
Ota, T1
Shinotoh, H1
Fukushi, K2
Nagatsuka, S2
Namba, H2
Iyo, M2
Aotsuka, A1
Tanaka, N1
Sato, K5
Shiraishi, T1
Tanada, S1
Arai, H3
Irie, T2
Kinomura, S4
Sato, T5
Kaneta, T3
Yamada, K1
Kizu, O1
Shidahara, M2
Taki, Y3
Okada, K3
Hanyu, H2
Shimizu, S1
Hirao, K1
Kanetaka, H1
Iwamoto, T2
Chikamori, T1
Usui, Y1
Yamashina, A1
Abe, K3
Kato, K2
Ikeda, M1
Tadokoro, M1
Abe, S2
Nakano, S1
Nishino, M1
Ishigaki, T1
Kanno, I1
Kimura, Y1
Kajimoto, K1
Katoh, H1
Tanaka, MR1
Hatazawa, J2
Kaneko, K2
Morioka, T1
Koga, H2
Sawamoto, H2
Ohya, N1
Yoshiura, T1
Mihara, F1
Honda, H2
Yoshikawa, H1
Yoshida, A1
Shishido, F1
Seino, O1
Inui, Y1
Toyama, H1
Manabe, Y1
Sarai, M1
Kosaka, K1
Iwata, N1
Katada, K1
Nakazawa, M2
Uemura, K2
Itoh, H1
Nishimura, H1
Onishi, Y1
Moretti, JL1
Tamgac, F1
Weinmann, P1
Caillat-Vigneron, N1
Belin, CA1
Cesaro, P1
Holman, BL1
Defer, G1
Matsuda, H1
Li, YM1
Higashi, S1
Sumiya, H1
Tsuji, S1
Kinuya, K1
Hisada, K1
Yamashita, J1
Ohkubo, M3
Odano, I3
Takahashi, N1
Takahashi, M2
Ohtaki, H3
Noguchi, E3
Kasahara, T2
Hatano, M2
Yokoi, T2
Suto, Y1
Kodama, F1
Tanabe, Y1
Tamagami, H1
Ikota, N1
Ishii, K1
Mori, E1
Kitagaki, H1
Sakamoto, S1
Yamaji, S1
Imamura, T1
Ikejiri, Y1
Kono, M1
Miyamoto, A1
Oki, J1
Takahashi, S1
Itoh, J1
Kusunoki, Y1
Shibaki, M1
Dobashi, Y1
Okamura, N1
Maruyama, M1
Higuchi, M1
Matsui, T1
Tanji, H1
Seki, T1
Hirai, H1
Chiba, H1
Itoh, M1
Sasaki, H1
Shiga, T1
Kubo, N1
Takano, A1
Kobayashi, J1
Takeda, Y1
Nakamura, F1
Katoh, C1
Koyama, T1
Tsukamoto, E1
Tamaki, N1
Asano, T1
Takasaki, M1
Killen, AR1
Oster, G1
Colditz, GA1

Reviews

1 review available for iofetamine and Sensitivity and Specificity

ArticleYear
Nuclear medicine imaging in tuberculosis using commercially available radiopharmaceuticals.
    Nuclear medicine communications, 2012, Volume: 33, Issue:6

    Topics: Diagnosis, Differential; Fluorodeoxyglucose F18; Gallium Radioisotopes; Humans; Iofetamine; Lung Neo

2012

Trials

17 trials available for iofetamine and Sensitivity and Specificity

ArticleYear
Simple assessment of cerebral hemodynamics using single-slab 3D time-of-flight MR angiography in patients with cervical internal carotid artery steno-occlusive diseases: comparison with quantitative perfusion single-photon emission CT.
    AJNR. American journal of neuroradiology, 2009, Volume: 30, Issue:3

    Topics: Acetazolamide; Aged; Aged, 80 and over; Carotid Artery, Internal; Carotid Stenosis; Cerebrovascular

2009
Relationship between cognitive function and regional cerebral blood flow in Alzheimer's disease.
    Nuclear medicine communications, 2002, Volume: 23, Issue:8

    Topics: Aged; Alzheimer Disease; Brain; Cerebrovascular Circulation; Cognition; Cognition Disorders; Female;

2002
Detection of misery perfusion with split-dose 123I-iodoamphetamine single-photon emission computed tomography in patients with carotid occlusive diseases.
    Stroke, 2002, Volume: 33, Issue:9

    Topics: Acetazolamide; Adult; Aged; Blood Volume; Brain; Carotid Artery Diseases; Cerebrovascular Circulatio

2002
Regional differences in distribution volume of I-123 IMP in the human brain: effect on CBF calculated by ARG method.
    Annals of nuclear medicine, 2002, Volume: 16, Issue:5

    Topics: Adult; Autoradiography; Brain; Calibration; Cerebrovascular Circulation; Humans; Image Interpretatio

2002
Validation of the dual-table autoradiographic method to quantify two sequential rCBFs in a single SPET session with N-isopropyl-[123I] p-iodoamphetamine.
    European journal of nuclear medicine and molecular imaging, 2003, Volume: 30, Issue:7

    Topics: Acetazolamide; Algorithms; Autoradiography; Brain; Cerebrovascular Circulation; Cerebrovascular Diso

2003
Development of quantitative analysis method for stereotactic brain image: assessment of reduced accumulation in extent and severity using anatomical segmentation.
    Annals of nuclear medicine, 2003, Volume: 17, Issue:4

    Topics: Aged; Alzheimer Disease; Anatomy, Cross-Sectional; Brain; Brain Mapping; Female; Humans; Image Inter

2003
A simple method for the detection of abnormal brain regions in Alzheimer's disease patients using [11C]MP4A: comparison with [123I]IMP SPECT.
    Annals of nuclear medicine, 2004, Volume: 18, Issue:3

    Topics: Acetates; Acetylcholinesterase; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Carbon Radioisoto

2004
Error analysis of measured cerebral vascular response to acetazolamide stress by I-123-IMP autoradiographic method with single photon emission computed tomography: errors due to distribution volume of I-123-IMP.
    Annals of nuclear medicine, 2004, Volume: 18, Issue:3

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Autoradiography; Brain; Cerebral Arterial Diseases; C

2004
Diagnosis of Alzheimer's disease using brain perfusion SPECT and MR imaging: which modality achieves better diagnostic accuracy?
    European journal of nuclear medicine and molecular imaging, 2005, Volume: 32, Issue:4

    Topics: Aged; Alzheimer Disease; Brain; Brain Mapping; Cerebrovascular Circulation; Female; Humans; Imaging,

2005
Effects of tissue heterogeneity on cerebral vascular response to acetazolamide stress measured by an I-123-IMP autoradiographic method with single-photon emission computed tomography.
    Annals of nuclear medicine, 2005, Volume: 19, Issue:4

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Artifacts; Autoradiography; Cerebrovascular Circulati

2005
Low efficacy of 18F-FDG PET for detection of uveal malignant melanoma compared with 123I-IMP SPECT.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:3

    Topics: Adult; Aged; Female; Fluorodeoxyglucose F18; Humans; Iofetamine; Male; Melanoma; Middle Aged; Positr

2006
Database of normal human cerebral blood flow measured by SPECT: I. Comparison between I-123-IMP, Tc-99m-HMPAO, and Tc-99m-ECD as referred with O-15 labeled water PET and voxel-based morphometry.
    Annals of nuclear medicine, 2006, Volume: 20, Issue:2

    Topics: Brain; Cerebrovascular Circulation; Cysteine; Databases, Factual; Female; Humans; Imaging, Three-Dim

2006
Database of normal human cerebral blood flow measured by SPECT: II. Quantification of I-123-IMP studies with ARG method and effects of partial volume correction.
    Annals of nuclear medicine, 2006, Volume: 20, Issue:2

    Topics: Aged; Algorithms; Artifacts; Brain; Cerebrovascular Circulation; Databases, Factual; Female; Humans;

2006
Pre-surgical identification of epileptogenic areas in temporal lobe epilepsy by 123I-iomazenil SPECT: a comparison with IMP SPECT and FDG PET.
    Nuclear medicine communications, 2006, Volume: 27, Issue:11

    Topics: Adolescent; Adult; Epilepsy, Temporal Lobe; Female; Flumazenil; Fluorodeoxyglucose F18; Humans; Iodi

2006
Quantitative mapping of regional cerebral blood flow using iodine-123-IMP and SPECT.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1994, Volume: 35, Issue:12

    Topics: Amphetamines; Autoradiography; Brain; Cerebrovascular Circulation; Computer Simulation; Humans; Iodi

1994
[A functional diagnostic method by measuring of distribution volume of 123I-IMP with SPECT].
    Kaku igaku. The Japanese journal of nuclear medicine, 1996, Volume: 33, Issue:6

    Topics: Adult; Aged; Amphetamines; Brain; Brain Diseases; Female; Humans; Iodine Radioisotopes; Iofetamine;

1996
The effect of scatter correction on 123I-IMP brain perfusion SPET with the triple energy window method in normal subjects using SPM analysis.
    European journal of nuclear medicine and molecular imaging, 2002, Volume: 29, Issue:3

    Topics: Adult; Brain; Cerebrovascular Circulation; Humans; Image Enhancement; Imaging, Three-Dimensional; Io

2002

Other Studies

24 other studies available for iofetamine and Sensitivity and Specificity

ArticleYear
MM2-type sporadic Creutzfeldt-Jakob disease: new diagnostic criteria for MM2-cortical type.
    Journal of neurology, neurosurgery, and psychiatry, 2020, Volume: 91, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Cerebral Cortex; Cerebrovascular Circulation;

2020
Diagnosis of uveal malignant melanoma by a new semiquantitative assessment of N-isopropyl-p-[123I]-iodoamphetamine.
    Japanese journal of ophthalmology, 2011, Volume: 55, Issue:2

    Topics: Aged; Choroid Neoplasms; Diagnosis, Computer-Assisted; Female; Humans; Imaging, Three-Dimensional; I

2011
Accuracy of central benzodiazepine receptor binding potential/cerebral blood flow SPECT imaging for detecting misery perfusion in patients with unilateral major cerebral artery occlusive diseases: comparison with cerebrovascular reactivity to acetazolamid
    Clinical nuclear medicine, 2012, Volume: 37, Issue:3

    Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Area Under Curve; Arterial Occlusive Diseases; Carbon

2012
Which attenuation coefficient to use in combined attenuation and scatter corrections for quantitative brain SPET?
    European journal of nuclear medicine and molecular imaging, 2002, Volume: 29, Issue:7

    Topics: Adult; Brain; Cerebrovascular Circulation; Humans; Image Enhancement; Imaging, Three-Dimensional; Io

2002
Optimal inversion time for acquiring flow-sensitive alternating inversion recovery images to quantify regional cerebral blood flow.
    European radiology, 2002, Volume: 12, Issue:12

    Topics: Aged; Blood Circulation Time; Brain; Carotid Artery, Internal; Carotid Stenosis; Cerebrovascular Cir

2002
[Regional cerebral blood flow measured by three-dimensional stereotactic surface projections (3D-SSP) of 123I-IMP SPECT in Parkinson disease patients with cognitive impairment].
    Rinsho shinkeigaku = Clinical neurology, 2003, Volume: 43, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebrovascular Circulation; Cognition Disorders; Female

2003
Quantitative imaging of cerebral blood flow using SPECT with 123I-iodoamphetamine in neuropsychiatric systemic lupus erythematosus.
    The Journal of rheumatology, 2003, Volume: 30, Issue:9

    Topics: Adult; Cerebrovascular Circulation; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Iof

2003
Comparative value of brain perfusion SPECT and [(123)I]MIBG myocardial scintigraphy in distinguishing between dementia with Lewy bodies and Alzheimer's disease.
    European journal of nuclear medicine and molecular imaging, 2006, Volume: 33, Issue:3

    Topics: 3-Iodobenzylguanidine; Aged; Alzheimer Disease; Brain; Diagnosis, Differential; Humans; Iofetamine;

2006
Diastolic blood pressure influences cerebrovascular reactivity measured by means of 123I-iodoamphetamine brain single photon emission computed tomography in medically treated patients with occlusive carotid or middle cerebral artery disease.
    Annals of nuclear medicine, 2006, Volume: 20, Issue:3

    Topics: Acetazolamide; Aged; Arterial Occlusive Diseases; Blood Pressure; Brain; Carotid Artery Diseases; Ce

2006
Clinical role of 123I-IMP SPECT for the differential diagnosis of ocular malignant melanoma: a time-course analysis.
    Nuclear medicine communications, 2007, Volume: 28, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Diagnosis, Differential; Eye Neoplasms; Female; H

2007
Evaluation of cerebral perfusion in patients with neuropsychiatric systemic lupus erythematosus using 123I-IMP SPECT.
    Annals of nuclear medicine, 2007, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Brain; Cerebrovascular Circulation; Diagnosis, Differential; Female; Humans; Iofe

2007
Evaluation of probable or possible dementia with lewy bodies using 123I-IMP brain perfusion SPECT, 123I-MIBG, and 99mTc-MIBI myocardial SPECT.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2007, Volume: 48, Issue:10

    Topics: 3-Iodobenzylguanidine; Aged; Aged, 80 and over; Brain; Female; Heart; Humans; Imaging, Three-Dimensi

2007
[Quantitation of regional cerebral blood flow using 123I-IMP from a single SPECT scan and a single blood sampling--analysis on statistical error source and optimal scan time].
    Kaku igaku. The Japanese journal of nuclear medicine, 1995, Volume: 32, Issue:3

    Topics: Amphetamines; Blood Specimen Collection; Brain; Cerebrovascular Circulation; Humans; Iodine Radioiso

1995
Early and delayed brain SPECT with technetium-99m-ECD and iodine-123-IMP in subacute strokes.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1994, Volume: 35, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Amphetamines; Brain; Cerebrovascular Disorders; Cysteine; Female; Hu

1994
Comparative SPECT study of stroke using Tc-99m ECD, I-123 IMP, and Tc-99m HMPAO.
    Clinical nuclear medicine, 1993, Volume: 18, Issue:9

    Topics: Adult; Amphetamines; Cerebellum; Cerebral Cortex; Cerebrovascular Disorders; Cysteine; Female; Human

1993
[A study on accuracy of rCBF measurements using the conventional microsphere method with N-isopropyl-p-[123I]iodoamphetamine and SPECT].
    Kaku igaku. The Japanese journal of nuclear medicine, 1995, Volume: 32, Issue:12

    Topics: Amphetamines; Brain; Cerebrovascular Circulation; Humans; Iodine Radioisotopes; Iofetamine; Microsph

1995
Accumulation of 123I-IMP in extrahepatic metastases of hepatocellular carcinoma.
    Nuclear medicine communications, 1995, Volume: 16, Issue:11

    Topics: Adrenal Gland Neoplasms; Amphetamines; Bone Neoplasms; Carcinoma, Hepatocellular; Case-Control Studi

1995
Brain acetylcholinesterase activity: validation of a PET tracer in a rat model of Alzheimer's disease.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:4

    Topics: Acetates; Acetylcholinesterase; Alzheimer Disease; Amphetamines; Animals; Brain; Carbon Radioisotope

1996
The clinical utility of visual evaluation of scintigraphic perfusion patterns for Alzheimer's disease using I-123 IMP SPECT.
    Clinical nuclear medicine, 1996, Volume: 21, Issue:2

    Topics: Aged; Alzheimer Disease; Amphetamines; Brain; Cognition Disorders; Dementia; Diagnosis, Differential

1996
Serial imaging in MELAS.
    Neuroradiology, 1997, Volume: 39, Issue:6

    Topics: Amphetamines; Brain; Child; Energy Metabolism; Fatal Outcome; Female; Humans; Iodine Radioisotopes;

1997
[A study on accuracy of rCBF measurements loaded with acetazolamide based on the microsphere model using iodine-123-IMP SPECT].
    Kaku igaku. The Japanese journal of nuclear medicine, 1998, Volume: 35, Issue:3

    Topics: Acetazolamide; Adult; Amphetamines; Brain; Cerebral Infarction; Cerebrovascular Circulation; Female;

1998
Combined Analysis of CSF Tau Levels and [(123)I]Iodoamphetamine SPECT in Mild Cognitive Impairment: Implications for a Novel Predictor of Alzheimer's Disease.
    The American journal of psychiatry, 2002, Volume: 159, Issue:3

    Topics: Aged; Alzheimer Disease; Cognition Disorders; Diagnosis, Differential; Female; Gyrus Cinguli; Humans

2002
[Diagnostic accuracy of single photon emission CT in Alzheimer-type dementia].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1992, Volume: 29, Issue:6

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amphetamines; Cerebrovascular Circulation; Female; Human

1992
An assessment of the role of 123I-N-isopropyl-p-iodoamphetamine with single-photon emission computed tomography in the diagnosis of stroke and Alzheimer's disease.
    Nuclear medicine communications, 1989, Volume: 10, Issue:4

    Topics: Alzheimer Disease; Amphetamines; Cerebrovascular Disorders; Humans; Iodine Radioisotopes; Iofetamine

1989