Page last updated: 2024-10-15

darbufelone

Description

darbufelone: RN given for (Z)-isomer and monomethanesulfonate salt; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID135564773
MeSH IDM0397550

Synonyms (13)

Synonym
darbufelone
5-((z)-3,5-di-tert-butyl-4-hydroxybenzylidene)-2-imino-4-thiazolidinone
darbufelone [inn]
unii-72h8h6k34c
72h8h6k34c ,
5-((z)-3,5-di-tert-butyl-4-hydroxybenzylidene)-2-imino-4-thiazolidinone.
(z)-2-amino-5-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-4(5h)-thiazolone
AKOS022180891
DTXSID5047247
HY-101438
CS-0021331
Q27266074
4(5h)-thiazolone, 2-amino-5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-, (5z)-

Treatment

ExcerptReference
"Treatment with darbufelone also induced apoptosis by activating caspase-3 and caspase-8."( Darbufelone, a novel anti-inflammatory drug, induces growth inhibition of lung cancer cells both in vitro and in vivo.
Ji, H; Lai, Y; Li, Y; Sun, Y; Ye, X; Zhang, Y; Zhou, W, 2010
)
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (14.29%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (85.71%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]