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indole-3-carbinol and Sensitivity and Specificity

indole-3-carbinol has been researched along with Sensitivity and Specificity in 5 studies

indole-3-carbinol: occurs in edible cruciferous vegetables
indole-3-methanol : An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"The mechanism of action of the anti-estrogen indole-3-carbinol (I3C), present in cruciferous vegetables, is being examined in our laboratory with a view to promote the use of this naturally occurring chemopreventive as an alternative to synthetic anti-estrogens in human breast cancer."7.71Multiple molecular targets of indole-3-carbinol, a chemopreventive anti-estrogen in breast cancer. ( Ashok, BT; Chen, YG; Garikapaty, VP; Liu, X; Mittelman, A; Roy, K; Seplowitz, R; Tiwari, RK; Tschorn, J, 2002)
"The mechanism of action of the anti-estrogen indole-3-carbinol (I3C), present in cruciferous vegetables, is being examined in our laboratory with a view to promote the use of this naturally occurring chemopreventive as an alternative to synthetic anti-estrogens in human breast cancer."3.71Multiple molecular targets of indole-3-carbinol, a chemopreventive anti-estrogen in breast cancer. ( Ashok, BT; Chen, YG; Garikapaty, VP; Liu, X; Mittelman, A; Roy, K; Seplowitz, R; Tiwari, RK; Tschorn, J, 2002)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Yu, X1
Ma, F1
Zhang, L1
Li, P1
Ashok, BT1
Chen, YG1
Liu, X1
Garikapaty, VP1
Seplowitz, R1
Tschorn, J1
Roy, K1
Mittelman, A1
Tiwari, RK1
Anderton, MJ1
Jukes, R1
Lamb, JH1
Manson, MM1
Gescher, A1
Steward, WP1
Williams, ML1
Parkin, DR1
Malejka-Giganti, D1
Sepkovic, DW1
Bradlow, HL1
Bell, M1

Other Studies

5 other studies available for indole-3-carbinol and Sensitivity and Specificity

ArticleYear
Extraction and Quantification of Sulforaphane and Indole-3-Carbinol from Rapeseed Tissues Using QuEChERS Coupled with UHPLC-MS/MS.
    Molecules (Basel, Switzerland), 2020, May-04, Volume: 25, Issue:9

    Topics: Brassica napus; Chromatography, High Pressure Liquid; Hydrolysis; Indoles; Isothiocyanates; Plant Ex

2020
Multiple molecular targets of indole-3-carbinol, a chemopreventive anti-estrogen in breast cancer.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2002, Volume: 11 Suppl 2

    Topics: Anticarcinogenic Agents; Base Sequence; BRCA1 Protein; Breast Neoplasms; Carrier Proteins; Estrogen

2002
Liquid chromatographic assay for the simultaneous determination of indole-3-carbinol and its acid condensation products in plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Apr-25, Volume: 787, Issue:2

    Topics: Calibration; Chromatography, High Pressure Liquid; Indoles; Reference Standards; Reproducibility of

2003
Differences in the hepatic P450-dependent metabolism of estrogen and tamoxifen in response to treatment of rats with 3,3'-diindolylmethane and its parent compound indole-3-carbinol.
    Cancer detection and prevention, 2004, Volume: 28, Issue:1

    Topics: Analysis of Variance; Animals; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid;

2004
Quantitative determination of 3,3'-diindolylmethane in urine of individuals receiving indole-3-carbinol.
    Nutrition and cancer, 2001, Volume: 41, Issue:1-2

    Topics: Anticarcinogenic Agents; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Indoles; P

2001