Page last updated: 2024-08-07 12:52:50
Thymidine kinase
[no definition available]
Synonyms
EC 2.7.1.21
Research
Bioassay Publications (7)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (8)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| thymidine | Human alphaherpesvirus 1 strain SC16 | Km | 0.8100 | 1 | 1 |
Design, synthesis and enzymatic activity of highly selective human mitochondrial thymidine kinase inhibitors.Bioorganic & medicinal chemistry letters, , May-21, Volume: 11, Issue:10, 2001
Understanding the binding of 5-substituted 2'-deoxyuridine substrates to thymidine kinase of herpes simplex virus type-1.Journal of medicinal chemistry, , Nov-22, Volume: 39, Issue:24, 1996
Quantitative structure-activity relationships of N2-phenylguanines as inhibitors of herpes simplex virus thymidine kinases.Journal of medicinal chemistry, , Aug-07, Volume: 35, Issue:16, 1992
Structure-activity relationships of N2-substituted guanines as inhibitors of HSV1 and HSV2 thymidine kinases.Journal of medicinal chemistry, , Volume: 33, Issue:1, 1990
N2-phenyldeoxyguanosine: a novel selective inhibitor of herpes simplex thymidine kinase.Journal of medicinal chemistry, , Volume: 31, Issue:8, 1988