Page last updated: 2024-08-07 18:52:22
Solute carrier family 22 member 8
An organic anion transporter 3 that is encoded in the genome of rat. [OMA:Q9R1U7, PRO:DNx]
Synonyms
Organic anion transporter 3;
rOat3
Research
Bioassay Publications (10)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 8 (80.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (26)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| hippuric acid | Rattus norvegicus (Norway rat) | Ki | 19.0000 | 1 | 1 |
| p-aminohippuric acid | Rattus norvegicus (Norway rat) | Ki | 683.0000 | 3 | 3 |
| cimetidine | Rattus norvegicus (Norway rat) | IC50 | 166.0000 | 1 | 1 |
| cimetidine | Rattus norvegicus (Norway rat) | Ki | 46.8000 | 1 | 1 |
| probenecid | Rattus norvegicus (Norway rat) | IC50 | 6.0300 | 1 | 1 |
| probenecid | Rattus norvegicus (Norway rat) | Ki | 12.2150 | 2 | 2 |
| cephaloridine | Rattus norvegicus (Norway rat) | Ki | 1,140.0000 | 1 | 1 |
| penicillin g | Rattus norvegicus (Norway rat) | Ki | 52.8000 | 1 | 1 |
| cephalothin | Rattus norvegicus (Norway rat) | Ki | 48.0000 | 1 | 1 |
| taurocholic acid | Rattus norvegicus (Norway rat) | Ki | 790.0000 | 1 | 1 |
| indoxyl acetate | Rattus norvegicus (Norway rat) | Ki | 582.0000 | 1 | 1 |
| cephalexin | Rattus norvegicus (Norway rat) | IC50 | 630.0000 | 1 | 1 |
| cefazolin | Rattus norvegicus (Norway rat) | Ki | 780.0000 | 1 | 1 |
| cefoperazone | Rattus norvegicus (Norway rat) | Ki | 670.0000 | 1 | 1 |
| cefadroxil anhydrous | Rattus norvegicus (Norway rat) | IC50 | 1,780.0000 | 2 | 2 |
| pravastatin | Rattus norvegicus (Norway rat) | IC50 | 15.6000 | 1 | 1 |
| betamipron | Rattus norvegicus (Norway rat) | IC50 | 47.5000 | 1 | 1 |
| dibromosulphthalein | Rattus norvegicus (Norway rat) | Ki | 3.0900 | 1 | 1 |
| cefamandole | Rattus norvegicus (Norway rat) | IC50 | 90.0000 | 1 | 1 |
| estrone sulfate | Rattus norvegicus (Norway rat) | Ki | 9.1000 | 1 | 1 |
| estradiol-17 beta-glucuronide | Rattus norvegicus (Norway rat) | Ki | 35.6000 | 1 | 1 |
| ceftriaxone | Rattus norvegicus (Norway rat) | IC50 | 2,000.0000 | 1 | 1 |
| cefotaxime | Rattus norvegicus (Norway rat) | IC50 | 800.0000 | 1 | 1 |
| cilastatin | Rattus norvegicus (Norway rat) | IC50 | 742.0000 | 1 | 1 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| homovanillic acid | Rattus norvegicus (Norway rat) | Km | 274.0000 | 1 | 1 |
| p-aminohippuric acid | Rattus norvegicus (Norway rat) | Km | 64.7000 | 1 | 1 |
| penicillin g | Rattus norvegicus (Norway rat) | Km | 82.6000 | 1 | 1 |
| indican | Rattus norvegicus (Norway rat) | Km | 166.0000 | 2 | 2 |
| pravastatin | Rattus norvegicus (Norway rat) | Km | 13.4000 | 1 | 1 |
| 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid | Rattus norvegicus (Norway rat) | Km | 11.0000 | 1 | 1 |
| ochratoxin a | Rattus norvegicus (Norway rat) | Km | 0.7390 | 1 | 1 |
| estrone sulfate | Rattus norvegicus (Norway rat) | Km | 2.3400 | 1 | 1 |