Proteins > Cholesterol side-chain cleavage enzyme, mitochondrial
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Cholesterol side-chain cleavage enzyme, mitochondrial
A cytochrome P450 11A1, mitochondrial that is encoded in the genome of cow. [OMA:P00189, PRO:DNx]
Synonyms
EC 1.14.15.6;
CYPXIA1;
Cholesterol desmolase;
Cytochrome P450 11A1;
Cytochrome P450(scc)
Research
Bioassay Publications (3)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (3)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| voriconazole | Bos taurus (cattle) | Kd | 4.8000 | 1 | 0 |
Synthesis and aromatase inhibition of 3-cycloalkyl-substituted 3-(4-aminophenyl)piperidine-2,6-diones.Journal of medicinal chemistry, , Jun-12, Volume: 35, Issue:12, 1992
Analogues of aminoglutethimide based on 1-phenyl-3-azabicyclo[3.1.0]hexane-2,4-dione: selective inhibition of aromatase activity.Journal of medicinal chemistry, , Volume: 31, Issue:5, 1988
Analogues of 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione as selective inhibitors of aromatase: derivatives with variable 1-alkyl and 3-alkyl substituents.Journal of medicinal chemistry, , Volume: 30, Issue:9, 1987