Page last updated: 2024-09-25

s 12363

Description

S 12363: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID154572898
MeSH IDM0176476

Synonyms (7)

Synonym
s-12363
vinfosiltine sulfate
s 12363
unii-jt6020n64h
vincaleukoblastine, o4-deacetyl-3-de(methoxycarbonyl)-3-(((1-(diethoxyphosphinyl)-2-methylpropyl)amino)carbonyl)-, (3(s))-, sulfate (1:1) (salt)
jt6020n64h ,
142102-11-2

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's12 (92.31)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials4 (22.22%)5.53%
Reviews1 (5.56%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (72.22%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research Highlights

Pharmacokinetics (2)

ArticleYear
Human pharmacokinetics of a new Vinca alkaloid S 12363 with use of a monoclonal antibody-based radio- or enzyme immunoassay.
Cancer research, Aug-01, Volume: 53, Issue: 15
1993
Value of early pharmacodynamic and pharmacokinetic investigations with anticancer drugs: data from phase I tolerance studies on a new vinca alkaloid derivative.
Xenobiotica; the fate of foreign compounds in biological systems, Volume: 22, Issue: 7
1992
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (5)

ArticleYear
Human pharmacokinetics of a new Vinca alkaloid S 12363 with use of a monoclonal antibody-based radio- or enzyme immunoassay.
Cancer research, Aug-01, Volume: 53, Issue: 15
1993
Evaluation of the time-schedule dependency for the cytotoxic activity of the new vinca alkaloid derivative, S 12363 (vinfosiltine).
European journal of cancer (Oxford, England : 1990), Volume: 29A, Issue: 13
1993
Preclinical antitumor activity of a new Vinca alkaloid derivative, S 12363.
Cancer research, May-01, Volume: 51, Issue: 9
1991
Value of early pharmacodynamic and pharmacokinetic investigations with anticancer drugs: data from phase I tolerance studies on a new vinca alkaloid derivative.
Xenobiotica; the fate of foreign compounds in biological systems, Volume: 22, Issue: 7
1992
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Interactions (1)

ArticleYear
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]