[no definition available]
Beta-CA 2;
EC 4.2.1.1;
Carbonate dehydratase 2;
mtCA 2
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| acetazolamide | Mycobacterium tuberculosis H37Rv | Ki | 0.0090 | 1 | 1 |
| celecoxib | Mycobacterium tuberculosis H37Rv | Ki | 0.7130 | 2 | 2 |
| dichlorphenamide | Mycobacterium tuberculosis H37Rv | Ki | 2.0100 | 1 | 1 |
| ethoxzolamide | Mycobacterium tuberculosis H37Rv | Ki | 0.0270 | 1 | 1 |
| mafenide | Mycobacterium tuberculosis H37Rv | Ki | 30.7000 | 1 | 1 |
| methazolamide | Mycobacterium tuberculosis H37Rv | Ki | 0.6600 | 1 | 1 |
| nipecotic acid | Mycobacterium tuberculosis H37Rv | Ki | 3.4233 | 1 | 3 |
| saccharin | Mycobacterium tuberculosis H37Rv | Ki | 0.7920 | 1 | 1 |
| sulfanilamide | Mycobacterium tuberculosis H37Rv | Ki | 19.0375 | 2 | 4 |
| sulpiride | Mycobacterium tuberculosis H37Rv | Ki | 0.2660 | 1 | 1 |
| sulthiame | Mycobacterium tuberculosis H37Rv | Ki | 0.6640 | 1 | 1 |
| zonisamide | Mycobacterium tuberculosis H37Rv | Ki | 0.8760 | 1 | 1 |
| 4-nitrobenzoic acid | Mycobacterium tuberculosis H37Rv | Ki | 4.8300 | 1 | 3 |
| 4-toluenesulfonamide | Mycobacterium tuberculosis H37Rv | Ki | 38.9000 | 1 | 1 |
| dichlone | Mycobacterium tuberculosis H37Rv | IC50 | 1.2000 | 1 | 1 |
| carzenide | Mycobacterium tuberculosis H37Rv | Ki | 39.2000 | 1 | 1 |
| 4-bromobenzoic acid | Mycobacterium tuberculosis H37Rv | Ki | 2.5133 | 1 | 3 |
| 4-cyanobenzoic acid | Mycobacterium tuberculosis H37Rv | Ki | 2.8367 | 1 | 3 |
| 2-methoxy-1,4-naphthoquinone | Mycobacterium tuberculosis H37Rv | IC50 | 2.3000 | 1 | 1 |
| benzolamide | Mycobacterium tuberculosis H37Rv | Ki | 0.5192 | 2 | 4 |
| acedoben | Mycobacterium tuberculosis H37Rv | Ki | 2.9700 | 1 | 3 |
| 4-amino-6-chloro-1,3-benzenedisulfonamide | Mycobacterium tuberculosis H37Rv | Ki | 32.5000 | 1 | 1 |
| brinzolamide | Mycobacterium tuberculosis H37Rv | Ki | 0.1270 | 1 | 1 |
| 2,4-disulfamyl-5-trifluoromethylaniline | Mycobacterium tuberculosis H37Rv | Ki | 29.6000 | 1 | 1 |
| 2-aminobenzenesulfonamide | Mycobacterium tuberculosis H37Rv | Ki | 33.7000 | 1 | 1 |
| 5-amino-1,3,4-thiadiazole-2-sulfonamide | Mycobacterium tuberculosis H37Rv | Ki | 2.0900 | 1 | 1 |
| valdecoxib | Mycobacterium tuberculosis H37Rv | Ki | 0.6820 | 2 | 2 |
| chlorzolamide | Mycobacterium tuberculosis H37Rv | Ki | 45.2000 | 1 | 1 |
| 4-(2-aminoethyl)benzenesulfonamide | Mycobacterium tuberculosis H37Rv | Ki | 29.1000 | 1 | 1 |
| n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide | Mycobacterium tuberculosis H37Rv | Ki | 0.7170 | 1 | 1 |
| ferulic acid | Mycobacterium tuberculosis H37Rv | Ki | 3.6633 | 1 | 3 |
| 2-hydroxycinnamic acid | Mycobacterium tuberculosis H37Rv | Ki | 2.1800 | 1 | 3 |
| trans-4-coumaric acid | Mycobacterium tuberculosis H37Rv | Ki | 1.7300 | 1 | 3 |
| caffeic acid | Mycobacterium tuberculosis H37Rv | Ki | 2.3600 | 1 | 3 |
| 2,6-dibromosulfanilamide | Mycobacterium tuberculosis H37Rv | Ki | 2.3200 | 1 | 3 |
| dorzolamide | Mycobacterium tuberculosis H37Rv | Ki | 0.0990 | 1 | 1 |
| topiramate | Mycobacterium tuberculosis H37Rv | Ki | 0.4740 | 1 | 1 |