Page last updated: 2024-10-15

orcokinin

Description

orcokinin: amino acid sequence given in first source; a myotropic peptide isolated from the crayfish Orconectes limosus [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	16132196
MeSH ID	M0211767

Synonyms (2)

Synonym
orcokinin
145344-97-4

Research Excerpts

Overview

Orcokinins are a family of myotropic neuropeptides widely present in various decapod crustaceans and insect species. The orcokinins enhance hindgut contractions in the crayfish Orconectes limosus.

Excerpt	Reference
"Orcokinins are a family of myotropic neuropeptides identified in various decapod crustaceans and recently in a cockroach. "	( Novel insect orcokinins: characterization and neuronal distribution in the brains of selected dicondylian insects. Dircksen, H; Hofer, S; Homberg, U; Tollbäck, P, 2005)
"Orcokinins are a family of myotropic neuropeptides widely present in various decapod crustaceans and insect species. "	( Investigation of several unique tandem mass spectrometric fragmentation patterns of NFDEIDR, an orcokinin analog, and its N-terminal dimethylated form. Fu, Q; Li, L, 2006)
"The orcokinins are a family of neuropeptides recently isolated from several crustacean species. "	( Orcokinin peptides in developing and adult crustacean stomatogastric nervous systems and pericardial organs. Kelley, WP; Li, L; Marder, E; Pulver, SR; Sweedler, JV; Thirumalai, V, 2002)
"The orcokinins are a highly conserved family of crustacean peptides that enhance hindgut contractions in the crayfish Orconectes limosus (Stangier et al. "	( Identification of orcokinins in single neurons in the stomatogastric nervous system of the crayfish, Cherax destructor. Dreger, M; Evers, JF; Hucho, F; Meseke, M; Skiebe, P, 2002)

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (54)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	3 (5.56)	18.2507
2000's	21 (38.89)	29.6817
2010's	24 (44.44)	24.3611
2020's	6 (11.11)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (1.79%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	55 (98.21%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
gamma-aminobutyric acid gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.. gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.	2.1	1	amino acid zwitterion; gamma-amino acid; monocarboxylic acid	human metabolite; neurotransmitter; Saccharomyces cerevisiae metabolite; signalling molecule
formaldehyde paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy	2.03	1	aldehyde; one-carbon compound	allergen; carcinogenic agent; disinfectant; EC 3.5.1.4 (amidase) inhibitor; environmental contaminant; Escherichia coli metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
methanol Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.. primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.. methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.	2.46	2	alkyl alcohol; one-carbon compound; primary alcohol; volatile organic compound	amphiprotic solvent; Escherichia coli metabolite; fuel; human metabolite; mouse metabolite; Mycoplasma genitalium metabolite
pyrrolidonecarboxylic acid Pyrrolidonecarboxylic Acid: A cyclized derivative of L-GLUTAMIC ACID. Elevated blood levels may be associated with problems of GLUTAMINE or GLUTATHIONE metabolism.. 5-oxo-L-proline : An optically active form of 5-oxoproline having L-configuration.	2.04	1	5-oxoproline; L-proline derivative; non-proteinogenic L-alpha-amino acid	algal metabolite
phenylalanyl-leucyl-arginyl phenylalaninamide phenylalanyl-leucyl-arginyl phenylalaninamide: RN given refers to all (L)-isomer; RN for cpd without isomeric designation not avail 11/90; involved in transmitter release	2.01	1
arginylphenylalaninamide arginylphenylalaninamide: RN given refers to (L,L)-isomer; fragment of FMRamide; may be used as a neurotransmitter or neuromodulator by optic lobe neurons of different types	2.1	1
proctolin proctolin: neurotransmitter in arthropods or invertebrates	2.95	4
salmfamide 2 SALMFamide 2: from radial nerve cords of the starfish Asterias rubens & Asterias forbesi; also from brittle star, Amphipholis squamata	2.17	1
allatostatin 1 allatostatin 1: inhibits juvenile hormone synthesis; from reproductively active females	3.76	10
fmrfamide FMRFamide: A molluscan neuroactive peptide which induces a fast excitatory depolarizing response due to direct activation of amiloride-sensitive SODIUM CHANNELS. (From Nature 1995; 378(6558): 730-3)	8.3	6
neuropeptide f neuropeptide F: amino acid sequence given in first source; MW 4433 Da; from tubellarian Artioposthia triangulata	3.16	5
corazonin protein, insect corazonin protein, insect: cardioactive peptide; isolated from a variety of insects	2.04	1
allatotropin allatotropin: from cerebral or corpora cardiaca of locusts & moths	2.48	2
crustacean cardioactive peptide crustacean cardioactive peptide: cardioactive neuropeptide, from the nervous system of the shore crab carcinus maenas; do not confuse with CCAP (katacalcin), a calcitonin carboxyl-terminal flanking peptide	2.97	4

Condition	Relationship Strength	Studies
Ganglion Cysts Nodular tumor-like lesions or mucoid flesh, arising from tendon sheaths, LIGAMENTS, or JOINT CAPSULE, especially of the hands, wrists, or feet. They are not true cysts as they lack epithelial wall. They are distinguished from SYNOVIAL CYSTS by the lack of communication with a joint cavity or the SYNOVIAL MEMBRANE.	2.44	2
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	2.02	1
Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.	2.43	2

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