Compounds > s-trichlorovinyl-n-acetylcysteine
Page last updated: 2024-12-07

s-trichlorovinyl-n-acetylcysteine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID119577
CHEBI ID165889
SCHEMBL ID16097635
MeSH IDM0151432

Synonyms (25)

Synonym
l-cysteine, n-acetyl-s-(trichloroethenyl)-
s-trichlorovinyl-n-acetylcysteine
n-acetyl-s-(trichloroethenyl)-l-cysteine
ccris 1307
(2r)-2-acetamido-3-(1,2,2-trichloroethenylsulanyl)propanoic acid
111348-61-9
n-acetyl-s-(trichlorovinyl)-cysteine
CHEBI:165889
(2r)-2-acetamido-3-(1,2,2-trichloroethenylsulfanyl)propanoic acid
n-acetyl-s-(trichlorovinyl)cysteine
unii-okq3s0ej8y
okq3s0ej8y ,
n-acetyl-s-(trichlorovinyl)-l-cysteine
l-cysteine,n-acetyl-s-(1,2,2-trichloroethenyl)-
SCHEMBL16097635
n-acetyl-s-(1,2,2-trichlorovinyl)-l-cysteine
l-cysteine, n-acetyl-s-(1,2,2-trichloroethenyl)-
DTXSID20149602
J-002563
AKOS030240573
(2r)-2-acetamido-3-(1,2,2-trichlorovinylsulfanyl)propanoic acid
Q27896755
(r)-2-acetamido-3-((1,2,2-trichlorovinyl)thio)propanoic acid
STARBLD0019568
(2r)-2-acetamido-3-[(1,2,2-trichloroethenyl)sulfanyl]propanoic acid

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Data are also presented for the isolation and analysis of this compound obtained from dosed rats."( Quantitation of the tetrachloroethylene metabolite N-acetyl-S-(trichlorovinyl)cysteine in rat urine via negative ion chemical ionization gas chromatography/tandem mass spectrometry.
Bartels, MJ, 1994)		0.29
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
N-acyl-L-amino acidAny N-acylamino acid having L-configuration.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.67

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.67 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.62 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.67)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
ethylene chlorohydrin
Ethylene Chlorohydrin: Used as a solvent, in the manufacture of insecticides, and for treating sweet potatoes before planting. May cause nausea, vomiting, pains in head and chest, stupefaction. Irritates mucous membranes and causes kidney and liver degeneration.. chloroethanol : An organochlorine compound that is ethanol substituted by at least one chloro group.		1.9910chloroethanolxenobiotic metabolite
trichloroacetic acid
Trichloroacetic Acid: A strong acid used as a protein precipitant in clinical chemistry and also as a caustic for removing warts.. trichloroacetic acid : A monocarboxylic acid that is acetic acid in which all three methyl hydrogens are substituted by chlorine.		1.9910monocarboxylic acid;
organochlorine compound		carcinogenic agent;
metabolite;
mouse metabolite
dichloroacetic acid
[no description available]		1.9910monocarboxylic acid;
organochlorine compound		astringent;
marine metabolite
2,2,2-trichloroethanol
[no description available]		1.9910chloroethanolmouse metabolite
acetylcysteine
N-acetyl-L-cysteine : An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.		3.2360acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary
tetrachloroethylene
Tetrachloroethylene: A chlorinated hydrocarbon used as an industrial solvent and cooling liquid in electrical transformers. It is a potential carcinogen.		2.940chlorocarbon;
chloroethenes		nephrotoxic agent
alkenes
[no description available]		1.9710
florox reagent
Florox Reagent: reagent for analysis of ketosteroids; structure		1.9810
s-1,2-dichlorovinyl-n-acetylcysteine
S-1,2-dichlorovinyl-N-acetylcysteine: urinary metabolite of trichloroethylene in mice		1.9710
n-acetyl-s-pentachloro-1,3-butadienylcysteine
N-acetyl-S-pentachloro-1,3-butadienylcysteine: RN given refers to (L)-isomer; structure given in first source		1.9710
ConditionIndicatedRelationship StrengthStudiesTrials
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		0210
Cancer of Kidney
[description not available]		01.9610
Kidney Neoplasms
Tumors or cancers of the KIDNEY.		01.9610