A protein that is a translation product of the PDR5 gene in yeast. [PRO:DNx, UniProtKB:P33302]
Pleiotropic drug resistance protein 5;
Suppressor of toxicity of sporidesmin
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| chlorpromazine | Saccharomyces cerevisiae S288C | IC50 | 4.5000 | 1 | 1 |
| fluphenazine | Saccharomyces cerevisiae S288C | IC50 | 1.7000 | 1 | 1 |
| imipramine | Saccharomyces cerevisiae S288C | IC50 | 22.0000 | 1 | 1 |
| perphenazine | Saccharomyces cerevisiae S288C | IC50 | 1.4000 | 1 | 1 |
| prochlorperazine | Saccharomyces cerevisiae S288C | IC50 | 1.7000 | 1 | 1 |
| promazine | Saccharomyces cerevisiae S288C | IC50 | 11.3000 | 1 | 1 |
| promethazine | Saccharomyces cerevisiae S288C | IC50 | 17.7000 | 1 | 1 |
| thiethylperazine | Saccharomyces cerevisiae S288C | IC50 | 2.3000 | 1 | 1 |
| thioridazine | Saccharomyces cerevisiae S288C | IC50 | 1.3000 | 1 | 1 |
| trifluoperazine | Saccharomyces cerevisiae S288C | IC50 | 1.4000 | 1 | 1 |
| triflupromazine | Saccharomyces cerevisiae S288C | IC50 | 4.9000 | 1 | 1 |
| phenothiazine | Saccharomyces cerevisiae S288C | IC50 | 400.0000 | 1 | 1 |
| amineptin | Saccharomyces cerevisiae S288C | IC50 | 400.0000 | 1 | 1 |
| diethazine | Saccharomyces cerevisiae S288C | IC50 | 10.3000 | 1 | 1 |
| methotrimeprazine | Saccharomyces cerevisiae S288C | IC50 | 9.6000 | 1 | 1 |
| didemethylchlorpromazine | Saccharomyces cerevisiae S288C | IC50 | 3.2000 | 1 | 1 |
| chlorprothixene | Saccharomyces cerevisiae S288C | IC50 | 5.1000 | 1 | 1 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| chlorpromazine | Saccharomyces cerevisiae S288C | INH | 57.0000 | 1 | 1 |
| fluphenazine | Saccharomyces cerevisiae S288C | INH | 5.4000 | 1 | 1 |
| imipramine | Saccharomyces cerevisiae S288C | INH | 166.0000 | 1 | 1 |
| perphenazine | Saccharomyces cerevisiae S288C | INH | 6.4000 | 1 | 1 |
| prochlorperazine | Saccharomyces cerevisiae S288C | INH | 7.2000 | 1 | 1 |
| promazine | Saccharomyces cerevisiae S288C | INH | 96.0000 | 1 | 1 |
| promethazine | Saccharomyces cerevisiae S288C | INH | 285.0000 | 1 | 1 |
| thiethylperazine | Saccharomyces cerevisiae S288C | INH | 5.6000 | 1 | 1 |
| thioridazine | Saccharomyces cerevisiae S288C | INH | 17.0000 | 1 | 1 |
| trifluoperazine | Saccharomyces cerevisiae S288C | INH | 8.3000 | 1 | 1 |
| triflupromazine | Saccharomyces cerevisiae S288C | INH | 47.0000 | 1 | 1 |
| phenothiazine | Saccharomyces cerevisiae S288C | INH | 433.0000 | 1 | 1 |
| amineptin | Saccharomyces cerevisiae S288C | INH | 433.0000 | 1 | 1 |
| diethazine | Saccharomyces cerevisiae S288C | INH | 331.0000 | 1 | 1 |
| methotrimeprazine | Saccharomyces cerevisiae S288C | INH | 128.0000 | 1 | 1 |
| didemethylchlorpromazine | Saccharomyces cerevisiae S288C | INH | 4.2000 | 1 | 1 |
| chlorprothixene | Saccharomyces cerevisiae S288C | INH | 26.0000 | 1 | 1 |