Page last updated: 2024-08-08 00:00:28
Structural capsid protein
[no definition available]
Synonyms
Research
Bioassay Publications (6)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 4 (66.67) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| ebselen | Human immunodeficiency virus 1 | IC50 | 0.0467 | 1 | 1 |
| pf-3450074 | Human immunodeficiency virus 1 | IC50 | 4.5750 | 2 | 2 |
| pf-3450074 | Human immunodeficiency virus 1 | Ki | 0.1200 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| pf-3450074 | Human immunodeficiency virus 1 | Kd | 1.9451 | 11 | 11 |
Design, synthesis, and mechanistic investigations of phenylalanine derivatives containing a benzothiazole moiety as HIV-1 capsid inhibitors with improved metabolic stability.European journal of medicinal chemistry, , Jan-05, Volume: 227, 2022
Design, synthesis, and mechanism study of dimerized phenylalanine derivatives as novel HIV-1 capsid inhibitors.European journal of medicinal chemistry, , Dec-15, Volume: 226, 2021
Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities.Journal of medicinal chemistry, , 05-14, Volume: 63, Issue:9, 2020
Discovery of phenylalanine derivatives as potent HIV-1 capsid inhibitors from click chemistry-based compound library.European journal of medicinal chemistry, , Oct-05, Volume: 158, 2018
Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds.Journal of medicinal chemistry, , Jan-28, Volume: 59, Issue:2, 2016