Proteins > kappa-type opioid receptor isoform 1
Page last updated: 2024-08-07 15:15:31

kappa-type opioid receptor isoform 1

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (31)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
chloroxineHomo sapiens (human)IC5018.280020
clioquinolHomo sapiens (human)IC5018.895020
1-(2-pyridylazo)-2-naphtholHomo sapiens (human)IC5018.560020
8-(4-tolylsulfonylamino)quinolineHomo sapiens (human)IC502.570010
2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinoneHomo sapiens (human)IC5021.900020
5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxideHomo sapiens (human)IC5016.650020
2-[5-[(2-chlorophenyl)methylthio]-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]pyridineHomo sapiens (human)IC5032.000010
2-[5-[(2,4-dichlorophenyl)methylthio]-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]pyridineHomo sapiens (human)IC5032.000010
2-[5-[(4-bromophenyl)methylthio]-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]pyridineHomo sapiens (human)IC5032.000010
N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]-N-propyl-2-pyridinecarboxamideHomo sapiens (human)IC5032.000010
N-butyl-N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-2-pyridinecarboxamideHomo sapiens (human)IC5032.000010
6-[2-(2-methoxyphenyl)imino-3-(2-oxolanylmethyl)-4-thiazolyl]-4H-1,4-benzoxazin-3-oneHomo sapiens (human)IC5018.760020
N-[2,2,2-trichloro-1-[[(2,6-dichloroanilino)-sulfanylidenemethyl]amino]ethyl]carbamic acid (phenylmethyl) esterHomo sapiens (human)IC501.853840
4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-ylamino]ethyl]benzamideHomo sapiens (human)IC500.856860
N-[1-(cyclopentylamino)-2-methyl-1-oxobutan-2-yl]-N-(thiophen-2-ylmethyl)-2-pyridinecarboxamideHomo sapiens (human)IC5032.000010
N-[1-[(cyclohexylamino)-oxomethyl]cyclohexyl]-N-(2-furanylmethyl)-2-pyridinecarboxamideHomo sapiens (human)IC5032.000010
N-[1-(cyclohexylamino)-2-methyl-1-oxobutan-2-yl]-N-(2-furanylmethyl)-2-pyridinecarboxamideHomo sapiens (human)IC5032.000010
N-[1-[(cyclohexylamino)-oxomethyl]cyclohexyl]-N-(thiophen-2-ylmethyl)-2-pyrazinecarboxamideHomo sapiens (human)IC5032.000010
2-[(5-methyl-4-phenyl-2-thiazolyl)methyl]-4-thiazololHomo sapiens (human)IC5023.800020
2,5-dichloro-N-[5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl]-3-thiophenecarboxamideHomo sapiens (human)IC5020.365020
N-[1-[(cyclohexylamino)-oxomethyl]cyclohexyl]-N-(thiophen-2-ylmethyl)-2-pyridinecarboxamideHomo sapiens (human)IC5018.500020
nalmefeneHomo sapiens (human)IC500.639520
naloxone hydrochlorideHomo sapiens (human)IC500.399020
naltrexone hydrochlorideHomo sapiens (human)IC500.337020
N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamideHomo sapiens (human)IC5021.000020
4-methyl-N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamideHomo sapiens (human)IC5024.666720
4-methoxy-N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamideHomo sapiens (human)IC5021.000020
2-[5-[(3,4-dichlorophenyl)methylthio]-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]pyridineHomo sapiens (human)IC5032.000010
4-[[(4-ethylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-ylamino]ethyl]benzamideHomo sapiens (human)IC501.835020
LSM-2536Homo sapiens (human)IC500.081530

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (trans)-(+-)-isomerHomo sapiens (human)EC500.353520
2-[5-[(2-chlorophenyl)methylthio]-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]pyridineHomo sapiens (human)EC5010.267540
2-[5-[(2,4-dichlorophenyl)methylthio]-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]pyridineHomo sapiens (human)EC501.561340
2-[5-[(4-bromophenyl)methylthio]-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]pyridineHomo sapiens (human)EC502.698940
N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]-N-propyl-2-pyridinecarboxamideHomo sapiens (human)EC5021.000020
N-butyl-N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-2-pyridinecarboxamideHomo sapiens (human)EC5014.950020
N-[2,2,2-trichloro-1-[[(2,6-dichloroanilino)-sulfanylidenemethyl]amino]ethyl]carbamic acid (phenylmethyl) esterHomo sapiens (human)EC5032.000010
4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-ylamino]ethyl]benzamideHomo sapiens (human)EC5032.000010
N-[1-(cyclopentylamino)-2-methyl-1-oxobutan-2-yl]-N-(thiophen-2-ylmethyl)-2-pyridinecarboxamideHomo sapiens (human)EC501.716640
N-[1-[(cyclohexylamino)-oxomethyl]cyclohexyl]-N-(2-furanylmethyl)-2-pyridinecarboxamideHomo sapiens (human)EC500.416540
N-[1-(cyclohexylamino)-2-methyl-1-oxobutan-2-yl]-N-(2-furanylmethyl)-2-pyridinecarboxamideHomo sapiens (human)EC500.391040
N-[1-[(cyclohexylamino)-oxomethyl]cyclohexyl]-N-(thiophen-2-ylmethyl)-2-pyrazinecarboxamideHomo sapiens (human)EC500.292520
N-[1-[(cyclohexylamino)-oxomethyl]cyclohexyl]-N-(thiophen-2-ylmethyl)-2-pyridinecarboxamideHomo sapiens (human)EC500.194740
naltrexone hydrochlorideHomo sapiens (human)EC505.000010
N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamideHomo sapiens (human)EC5032.000010
4-methyl-N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamideHomo sapiens (human)EC5032.000010
4-methoxy-N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamideHomo sapiens (human)EC5032.000010
2-[5-[(3,4-dichlorophenyl)methylthio]-4-(2-furanylmethyl)-1,2,4-triazol-3-yl]pyridineHomo sapiens (human)EC500.607020
4-[[(4-ethylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-ylamino]ethyl]benzamideHomo sapiens (human)EC5026.000020