chlorpheniramine has been researched along with Sensitivity and Specificity in 23 studies
Chlorpheniramine: A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than PROMETHAZINE.
chlorphenamine : A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The results of the proposed method were in excellent agreement with those obtained from PLS and HPLC methods and can be satisfactorily used for routine analysis of multicomponent dosage forms." | 1.33 | Content uniformity and dissolution tests of triplicate mixtures by a double divisor-ratio spectra derivative method. ( Koundourellis, JE; Malliou, ET; Markopoulou, CK, 2005) |
| "A rapid, precise, and specific high-performance liquid chromatographic method is described for the simultaneous determination of paracetamol, phenylephrine HCI, and chlorpheniramine maleate in combined pharmaceutical dosage forms." | 1.31 | Simultaneous high-performance liquid chromatographic determination of paracetamol, phenylephrine HCl, and chlorpheniramine maleate in pharmaceutical dosage forms. ( Ozden, T; Senyuva, H, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 11 (47.83) | 29.6817 |
| 2010's | 9 (39.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, W | 1 |
| Deng, J | 1 |
| Qian, Y | 1 |
| Hou, XT | 1 |
| Zhu, Z | 1 |
| Zhao, M | 1 |
| Shang, E | 1 |
| Qian, D | 1 |
| Zeng, H | 1 |
| Pang, H | 1 |
| Duan, J | 1 |
| Boltia, SA | 1 |
| Soudi, AT | 1 |
| Elzanfaly, ES | 1 |
| Zaazaa, HE | 1 |
| Ding, Y | 1 |
| Huang, K | 1 |
| Chen, L | 1 |
| Yang, J | 1 |
| Xu, WY | 1 |
| Xu, XJ | 1 |
| Duan, R | 1 |
| Zhang, J | 3 |
| He, Q | 1 |
| Liu, X | 2 |
| Chen, X | 2 |
| Ismaiel, OA | 2 |
| Halquist, MS | 1 |
| Elmamly, MY | 1 |
| Shalaby, A | 1 |
| Thomas Karnes, H | 1 |
| Adutwum, LA | 1 |
| Kishikawa, N | 1 |
| Ohyama, K | 1 |
| Harada, S | 1 |
| Nakashima, K | 1 |
| Kuroda, N | 1 |
| Palabiyik, IM | 1 |
| Onur, F | 1 |
| Zhang, T | 1 |
| Jenkins, RG | 1 |
| Karnes, HT | 1 |
| Huang, YQ | 1 |
| You, JQ | 1 |
| Sun, W | 1 |
| Ding, L | 1 |
| Feng, YQ | 1 |
| Zhu, D | 1 |
| Li, X | 1 |
| Sun, J | 1 |
| You, T | 1 |
| Van Eeckhaut, A | 1 |
| Detaevernier, MR | 1 |
| Michotte, Y | 1 |
| Takagaki, T | 1 |
| Matsuda, M | 1 |
| Mizuki, Y | 1 |
| Terauchi, Y | 1 |
| Zhang, LQ | 1 |
| Wu, XH | 1 |
| Tang, X | 1 |
| Zhu, XL | 1 |
| Su, WT | 1 |
| Marín, A | 1 |
| Barbas, C | 1 |
| Markopoulou, CK | 1 |
| Malliou, ET | 1 |
| Koundourellis, JE | 1 |
| Liu, Y | 1 |
| Zhou, W | 1 |
| Gealy, R | 1 |
| Wright-Bourque, JL | 1 |
| Kraynak, AR | 1 |
| McKelvey, TW | 1 |
| Barnum, JE | 1 |
| Storer, RD | 1 |
| Robinson, MK | 1 |
| Cruze, CA | 1 |
| Gasco-Lopez, AI | 1 |
| Izquierdo-Hornillos, R | 1 |
| Jiminez, A | 1 |
| D'Agostino, RB | 2 |
| Weintraub, M | 1 |
| Russell, HK | 1 |
| Stepanians, M | 1 |
| Cantilena, LR | 1 |
| Graumlich, JF | 1 |
| Maldonado, S | 1 |
| Honig, P | 1 |
| Anello, C | 1 |
| Celma, C | 1 |
| Allué, JA | 1 |
| Pruñonosa, J | 1 |
| Peraire, C | 1 |
| Obach, R | 1 |
| Senyuva, H | 1 |
| Ozden, T | 1 |
1 review available for chlorpheniramine and Sensitivity and Specificity
| Article | Year |
|---|---|
The effectiveness of antihistamines in reducing the severity of runny nose and sneezing: a meta-analysis.
Topics: Chlorpheniramine; Clinical Trials as Topic; Doxylamine; Histamine H1 Antagonists; Humans; Nasal Obst | 1998 |
22 other studies available for chlorpheniramine and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous determination of kaempferol, quercetin, mangiferin, gallic acid, p-hydroxybenzoic acid and chlorpheniramine maleate in rat plasma after oral administration of Mang-Guo-Zhi-Ke tablets by UHPLC-MS/MS and its application to pharmacokinetics.
Topics: Administration, Oral; Animals; Chlorpheniramine; Chromatography, High Pressure Liquid; Drugs, Chines | 2018 |
Simultaneous Quantification of Chlorpheniramine, Phenylephrine, Guaifenesin in Presence of Preservatives with Detection of Related Substance Guaiacol in their Cough Syrup by RP-HPLC and TLC-Densitometric Methods.
Topics: Antitussive Agents; Chlorpheniramine; Chromatography, High Pressure Liquid; Chromatography, Thin Lay | 2019 |
Simultaneous quantitative analysis of dextromethorphan, dextrorphan and chlorphenamine in human plasma by liquid chromatography-electrospray tandem mass spectrometry.
Topics: Adult; Chlorpheniramine; Chromatography, High Pressure Liquid; Dextromethorphan; Dextrorphan; Drug S | 2014 |
Online concentration by head-column field-amplified with large-volume sample stacking using flow injection-capillary electrophoresis for the analysis of four active components in cold medicines.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Allergic Agents; Antitussive Agents; Chlorpheniramine; | 2008 |
Monitoring phospholipids for assessment of ion enhancement and ion suppression in ESI and APCI LC/MS/MS for chlorpheniramine in human plasma and the importance of multiple source matrix effect evaluations.
Topics: Chlorpheniramine; Chromatography, Liquid; Diphenhydramine; Glycerylphosphorylcholine; Histamine H1 A | 2008 |
Peroxyoxalate chemiluminescence detection for the highly sensitive determination of fluorescence-labeled chlorpheniramine with Suzuki coupling reaction.
Topics: Chlorpheniramine; Chromatography, High Pressure Liquid; Fluorescence; Fluorescent Dyes; Humans; Lumi | 2010 |
Multivariate optimization and validation of a capillary electrophoresis method for the simultaneous determination of dextromethorphan hydrobromur, phenylephrine hydrochloride, paracetamol and chlorpheniramine maleate in a pharmaceutical preparation using
Topics: Acetaminophen; Chlorpheniramine; Chromatography, High Pressure Liquid; Dextromethorphan; Electrophor | 2010 |
Investigation of endogenous blood plasma phospholipids, cholesterol and glycerides that contribute to matrix effects in bioanalysis by liquid chromatography/mass spectrometry.
Topics: Chemical Fractionation; Chlorpheniramine; Cholesterol; Chromatography, Liquid; Erythrocytes; Glyceri | 2010 |
Application of experimental design in optimization of the separation condition for determination of four active components in cold medicines by flow injection-capillary electrophoresis.
Topics: Acetaminophen; Analysis of Variance; Chlorpheniramine; Dextromethorphan; Electrophoresis, Capillary; | 2011 |
Coupling frontal elution paper chromatography with desorption corona beam ionization mass spectrometry for rapid analysis of chlorphenamine in herbal medicines and dietary supplements.
Topics: Chlorpheniramine; Chromatography, Liquid; Dietary Supplements; Drugs, Chinese Herbal; Ethanol; Linea | 2011 |
Chemometrics optimization of six antihistamines separations by capillary electrophoresis with electrochemiluminescence detection.
Topics: Buffers; Chlorpheniramine; Cyproheptadine; Diphenhydramine; Doxylamine; Electrochemistry; Electropho | 2012 |
Development of a validated capillary electrophoresis method for enantiomeric purity testing of dexchlorpheniramine maleate.
Topics: Chlorpheniramine; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Reproducibility | 2002 |
Simple and sensitive method for the determination of chlorpheniramine maleate in human plasma using liquid chromatography-mass spectrometry.
Topics: Chlorpheniramine; Chromatography, Liquid; Histamine H1 Antagonists; Humans; Mass Spectrometry; Refer | 2002 |
[Research into simultaneous spectrophotometric determination of components in cough syrup by principal component regression method].
Topics: Acetaminophen; Aminophenols; Analgesics, Non-Narcotic; Caffeine; Chlorpheniramine; Drug Combinations | 2002 |
LC/MS for the degradation profiling of cough-cold products under forced conditions.
Topics: Acetaminophen; Chlorpheniramine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug | 2004 |
Content uniformity and dissolution tests of triplicate mixtures by a double divisor-ratio spectra derivative method.
Topics: Acetaminophen; Aspirin; Caffeine; Chlorpheniramine; Chromatography, High Pressure Liquid; Reproducib | 2005 |
Determination of chlorpheniramine and its binding with human serum albumin by capillary electrophoresis with tris(2,2'-bipyridyl)ruthenium(II) electrochemiluminescence detection.
Topics: Binding Sites; Chlorpheniramine; Electrochemistry; Electrophoresis, Capillary; Humans; Luminescent M | 2006 |
Validation of a high-throughput in vitro alkaline elution/rat hepatocyte assay for DNA damage.
Topics: Animals; Biological Assay; Cell Survival; Cells, Cultured; Chlorophenols; Chlorpheniramine; DNA; DNA | 2007 |
Preclinical skin sensitization testing of antihistamines: guinea pig and local lymph node assay responses.
Topics: Animals; Chlorpheniramine; Dermatitis, Allergic Contact; Diphenhydramine; Evaluation Studies as Topi | 1996 |
Development and validation of a high-performance liquid chromatography method for the determination of cold relief ingredients in chewing gum.
Topics: Acetaminophen; Chewing Gum; Chlorpheniramine; Chromatography, High Pressure Liquid; Ephedrine; Place | 1997 |
Simultaneous determination of paracetamol and chlorpheniramine in human plasma by liquid chromatography-tandem mass spectrometry.
Topics: Acetaminophen; Chlorpheniramine; Chromatography, Liquid; Humans; Mass Spectrometry; Reference Standa | 2000 |
Simultaneous high-performance liquid chromatographic determination of paracetamol, phenylephrine HCl, and chlorpheniramine maleate in pharmaceutical dosage forms.
Topics: Acetaminophen; Calibration; Chlorpheniramine; Chromatography, High Pressure Liquid; Dosage Forms; Ph | 2002 |