A lanosterol 14-alpha demethylase that is encoded in the genome of rat. [OMA:Q64654, PRO:DNx]
LDM;
EC 1.14.14.154;
CYPLI;
Cytochrome P450 51A1;
Cytochrome P450-14DM;
Cytochrome P45014DM;
Cytochrome P450LI;
Sterol 14-alpha demethylase
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| ketoconazole | Rattus norvegicus (Norway rat) | IC50 | 0.0830 | 1 | 2 |
| ketoconazole | Rattus norvegicus (Norway rat) | Ki | 0.0650 | 1 | 1 |
| raubasine | Rattus norvegicus (Norway rat) | Ki | 0.0057 | 1 | 1 |