thymine has been researched along with Sensitivity and Specificity in 43 studies
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Similar results were seen with a Cockayne syndrome B (CSB) cell line." | 2.41 | Factors influencing the removal of thymine glycol from DNA in gamma-irradiated human cells. ( Cooper, PK; Le, XC; Leadon, SA; Lee, J; Weinfeld, M; Xing, JZ, 2001) |
| "The Hollow Fibre Assay (HFA) is usually applied as an early in vivo model for anti-cancer drug screening, but is potentially an excellent model for short-term in vivo pharmacodynamic studies." | 1.34 | The Hollow Fibre Assay as a model for in vivo pharmacodynamics of fluoropyrimidines in colon cancer cells. ( Peters, GJ; Prins, HJ; Temmink, OH; van Gelderop, E, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (23.26) | 18.2507 |
| 2000's | 17 (39.53) | 29.6817 |
| 2010's | 16 (37.21) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beć, KB | 1 |
| Grabska, J | 1 |
| Ozaki, Y | 1 |
| Czarnecki, MA | 1 |
| Huck, CW | 1 |
| Jacobs, BAW | 1 |
| Pluim, D | 1 |
| van der Laan, P | 1 |
| Tzani, A | 1 |
| Beijnen, JH | 1 |
| Schellens, JHM | 1 |
| Chung, FH | 1 |
| Chiang, YR | 1 |
| Tseng, AL | 1 |
| Sung, YC | 1 |
| Lu, J | 1 |
| Huang, MC | 1 |
| Ma, N | 1 |
| Lee, HC | 1 |
| Wang, G | 2 |
| Zhou, Y | 2 |
| Huang, FJ | 1 |
| Tang, HD | 1 |
| Xu, XH | 1 |
| Liu, JJ | 1 |
| Wang, Y | 2 |
| Deng, YL | 1 |
| Ren, RJ | 1 |
| Xu, W | 1 |
| Ma, JF | 1 |
| Zhang, YN | 1 |
| Zhao, AH | 1 |
| Chen, SD | 1 |
| Jia, W | 1 |
| Zhu, Y | 1 |
| Chen, L | 1 |
| Zhang, X | 2 |
| Xu, Z | 1 |
| Lan, T | 1 |
| Huang, X | 1 |
| Dong, C | 1 |
| Ren, J | 1 |
| Zhang, L | 1 |
| Cai, QY | 1 |
| Li, J | 2 |
| Ge, J | 1 |
| Wang, JY | 1 |
| Dong, ZZ | 1 |
| Li, ZH | 1 |
| Wang, HB | 1 |
| Zhang, HD | 1 |
| Chen, Y | 1 |
| Liu, YM | 1 |
| Qiu, Z | 1 |
| Shu, J | 1 |
| Jin, G | 1 |
| Xu, M | 1 |
| Wei, Q | 1 |
| Chen, G | 1 |
| Tang, D | 1 |
| Lu, L | 1 |
| Kang, T | 1 |
| Cheng, S | 1 |
| Liu, FT | 1 |
| Zhu, PQ | 1 |
| Ou, YX | 1 |
| Liu, WW | 1 |
| Xia, GF | 1 |
| Luo, HL | 1 |
| Colborn, JM | 1 |
| Byrd, BD | 1 |
| Koita, OA | 1 |
| Krogstad, DJ | 1 |
| Wang, H | 1 |
| Jin, J | 1 |
| Yang, R | 1 |
| Zuo, X | 1 |
| Wu, H | 2 |
| Toh, J | 1 |
| Li, SF | 1 |
| Deng, M | 1 |
| Du, Y | 1 |
| Yan, S | 1 |
| Huang, R | 1 |
| Weng, X | 1 |
| Yang, C | 1 |
| Zhou, X | 1 |
| Kanayama, N | 1 |
| Takarada, T | 1 |
| Maeda, M | 1 |
| Wang, P | 1 |
| Dai, Z | 1 |
| Zou, X | 1 |
| Qian, QM | 1 |
| Wang, YS | 2 |
| Yang, HX | 1 |
| Xue, JH | 1 |
| Liu, L | 1 |
| Zhou, B | 1 |
| Wang, JC | 1 |
| Yin, JC | 1 |
| Nakajima, N | 2 |
| Ionescu, P | 1 |
| Sato, Y | 1 |
| Hashimoto, M | 1 |
| Kuroita, T | 1 |
| Takahashi, H | 1 |
| Yoshikura, H | 2 |
| Sata, T | 1 |
| Weekes, D | 1 |
| Fogel, GB | 1 |
| Emura, T | 1 |
| Murakami, Y | 1 |
| Nakagawa, F | 1 |
| Fukushima, M | 1 |
| Kitazato, K | 1 |
| Rappaport, HP | 1 |
| Bruchmüller, I | 1 |
| Janetzko, K | 1 |
| Bugert, P | 1 |
| Mayaudon, V | 1 |
| Corash, L | 1 |
| Lin, L | 1 |
| Klüter, H | 1 |
| Schmidt, C | 1 |
| Hofmann, U | 1 |
| Kohlmüller, D | 1 |
| Mürdter, T | 1 |
| Zanger, UM | 1 |
| Schwab, M | 1 |
| Hoffmann, GF | 1 |
| Temmink, OH | 1 |
| Prins, HJ | 1 |
| van Gelderop, E | 1 |
| Peters, GJ | 1 |
| Tanaka, Y | 1 |
| Oda, S | 1 |
| Yamaguchi, H | 1 |
| Kondo, Y | 1 |
| Kojima, C | 1 |
| Ono, A | 1 |
| Rogstad, DK | 1 |
| Darwanto, A | 1 |
| Herring, JL | 1 |
| Rogstad, KN | 1 |
| Burdzy, A | 1 |
| Hadley, SR | 1 |
| Neidigh, JW | 1 |
| Sowers, LC | 1 |
| Sapio, MR | 1 |
| Guerra, A | 1 |
| Posca, D | 1 |
| Limone, PP | 1 |
| Deandrea, M | 1 |
| Motta, M | 1 |
| Troncone, G | 1 |
| Caleo, A | 1 |
| Vallefuoco, P | 1 |
| Rossi, G | 1 |
| Fenzi, G | 1 |
| Vitale, M | 1 |
| O'Neil, LL | 1 |
| Wiest, O | 1 |
| Li, D | 1 |
| Wieckowska, A | 1 |
| Willner, I | 1 |
| Vinogradov, AE | 1 |
| Rosanov, JM | 1 |
| Balzarini, J | 1 |
| Karlsson, A | 1 |
| De Clercq, E | 1 |
| Kang, H | 1 |
| Konishi, C | 2 |
| Kuroki, T | 2 |
| Huh, N | 1 |
| Strick, R | 1 |
| Laemmli, UK | 1 |
| Peters, R | 1 |
| Sikorski, R | 1 |
| Hanaki, K | 1 |
| Shimizu, YK | 1 |
| Ohnishi, S | 1 |
| Gunji, T | 1 |
| Nakajima, A | 1 |
| Nozaki, C | 1 |
| Mizuno, K | 1 |
| Odawara, T | 1 |
| Geyer, H | 1 |
| Schmitt, S | 1 |
| Wuhrer, M | 1 |
| Geyer, R | 1 |
| Robinson, JK | 1 |
| Scott, WG | 1 |
| Rowlen, KL | 1 |
| Birks, JW | 1 |
| Yang, HH | 1 |
| Zhu, QZ | 1 |
| Chen, QY | 1 |
| Li, DH | 1 |
| Xu, JG | 1 |
| Weinfeld, M | 1 |
| Xing, JZ | 1 |
| Lee, J | 1 |
| Leadon, SA | 1 |
| Cooper, PK | 1 |
| Le, XC | 1 |
| Gutfilen, B | 1 |
| Fonseca, LM | 1 |
| Kang, HI | 1 |
| Eberle, G | 1 |
| Rajewsky, MF | 1 |
| Huh, NH | 1 |
| Berger, M | 1 |
| Cadet, J | 1 |
| Berube, R | 1 |
| Langlois, R | 1 |
| van Lier, JE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Trifluridine/Tipiracil in Combination With Irinotecan as a Second Line Therapy in Patients With Cholangiocarcinoma[NCT04059562] | Phase 2 | 28 participants (Anticipated) | Interventional | 2021-10-28 | Active, not recruiting | ||
| Phase II Trial of TAS-102 in Patients With Advanced, Refractory Pancreatic Adenocarcinoma[NCT04923529] | Phase 2 | 28 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thymine and Sensitivity and Specificity
| Article | Year |
|---|---|
Positive association between IL-16 rs1131445 polymorphism and cancer risk: a meta-analysis.
Topics: Alleles; Asian People; Biomarkers, Tumor; Cytosine; Databases, Factual; Evidence-Based Medicine; Gen | 2016 |
Factors influencing the removal of thymine glycol from DNA in gamma-irradiated human cells.
Topics: Animals; Cells, Cultured; Cockayne Syndrome; DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, | 2001 |
1 trial available for thymine and Sensitivity and Specificity
| Article | Year |
|---|---|
Comparison of Tc-99m THY and Tc-99m MIBI scans for diagnosis of breast lesions.
Topics: Breast Diseases; Breast Neoplasms; Female; Humans; Mammography; Organotechnetium Compounds; Radionuc | 2001 |
40 other studies available for thymine and Sensitivity and Specificity
| Article | Year |
|---|---|
Simulated NIR spectra as sensitive markers of the structure and interactions in nucleobases.
Topics: Adenine; Binding Sites; Biophysical Phenomena; Computer Simulation; Crystallization; Cytosine; Guani | 2019 |
Development and validation of a quantitative method for thymidine phosphorylase activity in peripheral blood mononuclear cells.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Chromatography, High Pressure Liquid; Humans; Leukocy | 2018 |
Functional Module Connectivity Map (FMCM): a framework for searching repurposed drug compounds for systems treatment of cancer and an application to colorectal adenocarcinoma.
Topics: Adenocarcinoma; Algorithms; Colorectal Neoplasms; Drug Repositioning; Epistasis, Genetic; Ethacrynic | 2014 |
Plasma metabolite profiles of Alzheimer's disease and mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arachidonic Acid; Biomarkers; Chromatography, Liquid; Co | 2014 |
Dual hairpin-like molecular beacon based on coralyne-adenosine interaction for sensing melamine in dairy products.
Topics: Adenosine; Animals; Berberine Alkaloids; Biosensing Techniques; Dairy Products; Fluorescent Dyes; Fo | 2014 |
A sensitive assay of mercury using fluorescence correlation spectroscopy of gold nanoparticles.
Topics: Calibration; Cosmetics; Fluorescent Dyes; Gold; Limit of Detection; Mercury; Metal Nanoparticles; Ol | 2015 |
A label-free method for detecting biothiols based on poly(thymine)-templated copper nanoparticles.
Topics: Copper; Humans; Mercury; Metal Nanoparticles; Molecular Imprinting; Reproducibility of Results; Sens | 2015 |
A fluorescent biosensor for protein detection based on poly(thymine)-templated copper nanoparticles and terminal protection of small molecule-linked DNA.
Topics: Copper; DNA; Equipment Design; Equipment Failure Analysis; Metal Nanoparticles; Molecular Imprinting | 2015 |
Invertase-labeling gold-dendrimer for in situ amplified detection mercury(II) with glucometer readout and thymine-Hg(2+)-thymine coordination chemistry.
Topics: beta-Fructofuranosidase; Conductometry; Dendrimers; DNA Probes; Equipment Design; Equipment Failure | 2016 |
Intense charge transfer surface based on graphene and thymine-Hg(II)-thymine base pairs for detection of Hg(2.).
Topics: Base Pairing; Conductometry; DNA; Electron Transport; Environmental Monitoring; Equipment Design; Eq | 2016 |
Estimation of copy number using SYBR Green: confounding by AT-rich DNA and by variation in amplicon length.
Topics: Adenine; Animals; Anopheles; Base Sequence; Benzothiazoles; Diamines; DNA; DNA, Protozoan; Female; F | 2008 |
Gold nanoparticle-based colorimetric and "turn-on" fluorescent probe for mercury(II) ions in aqueous solution.
Topics: Base Sequence; Binding Sites; Biosensing Techniques; Cations, Divalent; Colorimetry; DNA, Single-Str | 2008 |
Mechanism of mercury detection based on interaction of single-strand DNA and hybridized DNA with gold nanoparticles.
Topics: Absorption; Base Pair Mismatch; Base Sequence; Colorimetry; DNA Probes; DNA, Single-Stranded; Fluore | 2010 |
A novel cationic triazatetrabenzcorrole: selective detection of mercury(II) by nucleic acid-induced aggregation.
Topics: Biosensing Techniques; Cations; DNA; Fluorescent Dyes; Mercury; Phosphorothioate Oligonucleotides; P | 2011 |
Rapid naked-eye detection of mercury ions based on non-crosslinking aggregation of double-stranded DNA-carrying gold nanoparticles.
Topics: Colorimetry; DNA; Environmental Pollutants; Gold; Ions; Mercury; Nanoparticles; Sensitivity and Spec | 2011 |
Simultaneous detection of guanine, adenine, thymine and cytosine at choline monolayer supported multiwalled carbon nanotubes film.
Topics: Adenine; Animals; Choline; Cytosine; DNA; Electrochemical Techniques; Fishes; Guanine; Nanotubes, Ca | 2011 |
Colorimetric detection of metallothioneins using a thymine-rich oligonucleotide-Hg complex and gold nanoparticles.
Topics: Colorimetry; Gold; Humans; Hydrogen-Ion Concentration; Mercury; Metal Nanoparticles; Metallothionein | 2013 |
In situ hybridization AT-tailing with catalyzed signal amplification for sensitive and specific in situ detection of human immunodeficiency virus-1 mRNA in formalin-fixed and paraffin-embedded tissues.
Topics: Adenine; Adult; Antigens, Viral; Base Sequence; Child; Child, Preschool; DNA Probes; Female; HIV-1; | 2003 |
Evolutionary optimization, backpropagation, and data preparation issues in QSAR modeling of HIV inhibition by HEPT derivatives.
Topics: Algorithms; Artificial Intelligence; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Lethal D | 2003 |
A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells.
Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colorectal Neoplasms; C | 2004 |
A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells.
Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colorectal Neoplasms; C | 2004 |
A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells.
Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colorectal Neoplasms; C | 2004 |
A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells.
Topics: Animals; Antimetabolites; Antimetabolites, Antineoplastic; Cell Line, Tumor; Colorectal Neoplasms; C | 2004 |
The fidelity of replication of the three-base-pair set adenine/thymine, hypoxanthine/cytosine and 6-thiopurine/5-methyl-2-pyrimidinone with T7 DNA polymerase.
Topics: Adenine; Base Pairing; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Hypoxanthine; Kinetic | 2004 |
Polymerase chain reaction inhibition assay documenting the amotosalen-based photochemical pathogen inactivation process of platelet concentrates.
Topics: Adenine; Bacterial Infections; Blood Banking; Blood Preservation; DNA Primers; DNA, Mitochondrial; E | 2005 |
Comprehensive analysis of pyrimidine metabolism in 450 children with unspecific neurological symptoms using high-pressure liquid chromatography-electrospray ionization tandem mass spectrometry.
Topics: Adolescent; beta-Alanine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dihydropyri | 2005 |
The Hollow Fibre Assay as a model for in vivo pharmacodynamics of fluoropyrimidines in colon cancer cells.
Topics: Administration, Oral; Animals; Apoptosis; Capecitabine; Cell Cycle; Cell Line, Tumor; Colonic Neopla | 2007 |
15N-15N J-coupling across Hg(II): direct observation of Hg(II)-mediated T-T base pairs in a DNA duplex.
Topics: Base Pairing; DNA; Magnetic Resonance Spectroscopy; Mercury; Molecular Structure; Nitrogen Isotopes; | 2007 |
Measurement of the incorporation and repair of exogenous 5-hydroxymethyl-2'-deoxyuridine in human cells in culture using gas chromatography-negative chemical ionization-mass spectrometry.
Topics: Biomarkers; Cell Line, Tumor; Cell Survival; DNA Damage; DNA Repair; Formates; Gas Chromatography-Ma | 2007 |
Combined analysis of galectin-3 and BRAFV600E improves the accuracy of fine-needle aspiration biopsy with cytological findings suspicious for papillary thyroid carcinoma.
Topics: Adenine; Adenocarcinoma, Papillary; Amino Acid Substitution; Biopsy, Fine-Needle; Galectin 3; Humans | 2007 |
Sequence dependence in base flipping: experimental and computational studies.
Topics: Base Pairing; Base Sequence; Computer Simulation; Cyclams; Dansyl Compounds; DNA; Fluorescence; Guan | 2008 |
Optical analysis of Hg2+ ions by oligonucleotide-gold-nanoparticle hybrids and DNA-based machines.
Topics: Colorimetry; DNA; Gold; Mercury; Metal Nanoparticles; Oligonucleotides; Optics and Photonics; Partic | 2008 |
Some properties of new DNA-specific bisbenzimidazole fluorochromes without a piperazine ring.
Topics: Adenine; Animals; Benzimidazoles; Bisbenzimidazole; Bromodeoxyuridine; DNA; Flow Cytometry; Fluoresc | 1993 |
Human immunodeficiency virus type 1 drug-resistance patterns with different 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives.
Topics: Antiviral Agents; Base Sequence; DNA Primers; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Hum | 1993 |
A highly sensitive and specific method for quantitation of O-alkylated DNA adducts and its application to the analysis of human tissue DNA.
Topics: Alkylating Agents; Alkylation; Chromatography, High Pressure Liquid; DNA; DNA Damage; Guanine; Human | 1993 |
SARs are cis DNA elements of chromosome dynamics: synthesis of a SAR repressor protein.
Topics: Adenine; Amino Acid Sequence; Animals; Base Sequence; Cell Nucleus; Chromatin; Chromosomes; DNA; DNA | 1995 |
Zeptomolar damage.
Topics: Antibodies, Monoclonal; DNA Damage; DNA Repair; DNA, Neoplasm; Electrophoresis, Capillary; Fluoresce | 1998 |
Hybridization-AT-tailing (HybrAT) method for sensitive and strand-specific detection of DNA and RNA.
Topics: Adenine; Base Sequence; DNA; DNA-Directed DNA Polymerase; Hepatitis C; Hepatitis C Antibodies; Human | 1998 |
Structural analysis of glycoconjugates by on-target enzymatic digestion and MALDI-TOF-MS.
Topics: Acetates; Buffers; Glycoconjugates; Glycolipids; Glycoproteins; Glycoside Hydrolases; Isomerism; Mol | 1999 |
Derivatization of thymine and thymine photodimers with 4-bromomethyl-7-methoxycoumarin for fluorescence detection in high-performance liquid chromatography.
Topics: Calibration; Chromatography, High Pressure Liquid; Indicators and Reagents; Photochemistry; Sensitiv | 1999 |
Application of magdala red as a fluorescence probe in the determination of nucleic acids.
Topics: Adenine; Animals; Cattle; Cytosine; DNA; Fluorescent Dyes; Guanine; Indicators and Reagents; Naphtha | 2000 |
Highly sensitive, specific detection of O6-methylguanine, O4-methylthymine, and O4-ethylthymine by the combination of high-performance liquid chromatography prefractionation, 32P postlabeling, and immunoprecipitation.
Topics: Chromatography, High Pressure Liquid; DNA; Guanosine; Humans; Hydrolysis; Isotope Labeling; Leukocyt | 1992 |
Reversed-phase high-performance liquid chromatography-thermospray mass spectrometry of radiation-induced decomposition products of thymine and thymidine.
Topics: Chromatography, High Pressure Liquid; Mass Spectrometry; Sensitivity and Specificity; Thymidine; Thy | 1992 |