Page last updated: 2024-11-09

3-amino-5-mercapto-1,2,4-triazole

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3-amino-5-mercapto-1,2,4-triazole: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID2723869
CHEMBL ID3187666
SCHEMBL ID94802
SCHEMBL ID11413174
MeSH IDM0470025

Synonyms (84)

Synonym
AC-16289
AKOS002350449
5-amino-4h-[1,2,4]triazole-3-thiol
nsc34807
nsc-34807
5-amino-1,2-dihydro-3h-1,2,4-triazole-3-thione
1,4-triazolidine-3-thione, 5-imino-
iminothiourazole
3-amino-5-mercapto-1,4-triazole
nsc-145149
3h-1,4-triazole-3-thione, 5-amino-1,2-dihydro-
16691-43-3
nsc145149
ent 61388
s-triazole-3-thiol, 5-amino-
3-imino-5-thiourazole
3-amino-1,2,4-triazole-5-thiol, 95%
5-amino-1,2-dihydro-3h,1,2,4-triazole-3-thione
nsc 145149
3-amino-1,2,4-triazole-5-thiol
3h-1,2,4-triazole-3-thione, 1,2-dihydro-5-amino-
1,2,4-triazolidine-3-thione, 5-imino-
3h-1,2,4-triazole-3-thione, 5-amino-1,2-dihydro-
3-amino-5-mercapto-1,2,4-triazole
1,2-triazolidine-3-thione, 5-imino-
1,2-dihydro-5-amino-3h-1,2,4-triazole-3-thione
ai3-61388
einecs 240-735-6
3-amino-4h-1,2,4-triazole-5-thiol
AKOS000276288
AKOS000813709
STK803268
3-amino-1h-1,2,4-triazole-5-thiol
AKOS001051876
5-amino-1,2-dihydro-1,2,4-triazole-3-thione
AKOS000119697
5-azanyl-1,2-dihydro-1,2,4-triazole-3-thione
A810790
unii-353f2d8l1z
353f2d8l1z ,
dtxcid5024849
dtxsid7044849 ,
cas-16691-43-3
NCGC00256233-01
tox21_301609
BBL004942
5-amino-4h-1,2,4-triazole-3-thiol
F3250-0579
BP-10581
FT-0615006
5-amino-1h-1,2,4-triazole-3-thiol
F9995-0407
SCHEMBL94802
5-amino-3-mercapto-4h-[1,2,4]triazole
3-amino-5-mercapto-1h-1,2,4-triazole
5-amino-3-mercapto-1,2,4-triazole
3-amino-5-mercapto-s-triazole
5-amino-3-mercapto-1,2,4--triazole
SCHEMBL11413174
W-107914
BS-3747
5-amino-4h-1,2,4-triazol-3-yl hydrosulfide #
3-mercapto-5-amino-1,2,4-triazole
5-amino-1h-(1,2,4)triazole-3-thiol
2-amino-5-mercapto-1,3,4-triazole
3-thio-5-amino-1,2,4-triazole
4h-3-amino-5-mercapto-1,2,4-triazole
5-mercapto-3-amino-1,2,4-triazole
CHEMBL3187666
mfcd00005231
VU0607279-1
CS-B1269
5-amino-3,4-dihydro-2h-1,2,4-triazole-3-thione
5-imino-1,2,4-triazolidine-3-thione
5-amino-1,2-dihydro-3h-1,2,4-tri-azole-3-thione
Q26841259
3-amino-5-mercapto-[1,2,4]triazole
AMY25588
mfcd00755416
amino-1,2,4-triazole-3-thiol
EN300-260497
5-amino-2,3-dihydro-1h-1,2,4-triazole-3-thione
Z56913172
PD148022

Research Excerpts

Toxicity

ExcerptReferenceRelevance
"We concluded that long-term exposure of astrocytes to ethanol is more toxic than acute exposure."( Comparison of ethanol and acetaldehyde toxicity in rat astrocytes in primary culture.
Lipnik-Stangelj, M; Sarc, L, 2009
)
0.35

Dosage Studied

ExcerptRelevanceReference
" The protein content study showed biphasic dose-response curves, after 24 hours and seven days of exposure to either ethanol or acetaldehyde."( Comparison of ethanol and acetaldehyde toxicity in rat astrocytes in primary culture.
Lipnik-Stangelj, M; Sarc, L, 2009
)
0.35
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (1)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
acetylcholinesteraseHomo sapiens (human)Potency89.35840.002541.796015,848.9004AID1347398
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (15)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (46.67)29.6817
2010's7 (46.67)24.3611
2020's1 (6.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 33.90

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index33.90 (24.57)
Research Supply Index2.83 (2.92)
Research Growth Index4.50 (4.65)
Search Engine Demand Index31.50 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (33.90)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other16 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]