| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
chloroacetaldehyde
[no description available] | 2.04 | 1 | 0 | organochlorine compound | |
ethylene chlorohydrin
Ethylene Chlorohydrin: Used as a solvent, in the manufacture of insecticides, and for treating sweet potatoes before planting. May cause nausea, vomiting, pains in head and chest, stupefaction. Irritates mucous membranes and causes kidney and liver degeneration.. chloroethanol : An organochlorine compound that is ethanol substituted by at least one chloro group. | 2.04 | 1 | 0 | chloroethanol | xenobiotic metabolite |
acetic acid
Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed). acetic acid : A simple monocarboxylic acid containing two carbons. | 2.21 | 1 | 0 | monocarboxylic acid | antimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent |
chloroacetic acid
chloroacetic acid: urinary metabolite of vinyl chloride; RN given refers to parent cpd; structure. chloroacetic acid : A chlorocarboxylic acid that is acetic acid carrying a 2-chloro substituent. | 2.76 | 3 | 0 | chlorocarboxylic acid;
haloacetic acid | alkylating agent;
herbicide |
iodoacetic acid
Iodoacetic Acid: A derivative of ACETIC ACID that contains one IODINE atom attached to its methyl group.. iodoacetic acid : A haloacetic acid that is acetic acid in which one of the hydrogens of the methyl group is replaced by an iodine atom. | 2.04 | 1 | 0 | haloacetic acid;
organoiodine compound | alkylating agent |
bromoacetate
[no description available] | 2.04 | 1 | 0 | carboxylic acid;
organohalogen compound | |
bromoacetate
[no description available] | 2.04 | 1 | 0 | | |
propane
Propane: A three carbon alkane with the formula H3CCH2CH3. | 2.08 | 1 | 0 | alkane;
gas molecular entity | food propellant |
2-bromopropane
2-bromopropane: used as a substitute for freon | 2.04 | 1 | 0 | | |
tribromoacetic acid
[no description available] | 3.16 | 5 | 0 | | |
trichloroacetic acid
Trichloroacetic Acid: A strong acid used as a protein precipitant in clinical chemistry and also as a caustic for removing warts.. trichloroacetic acid : A monocarboxylic acid that is acetic acid in which all three methyl hydrogens are substituted by chlorine. | 3.54 | 8 | 0 | monocarboxylic acid;
organochlorine compound | carcinogenic agent;
metabolite;
mouse metabolite |
2,3-dichloro-1-propene
2,3-dichloro-1-propene: soil fumigant | 2.04 | 1 | 0 | | |
2,2-dichloroacetyl chloride
dichloroacetyl chloride : The acyl chloride obtained by displacement of the hydroxy group of dichloroacetic acid by chloride. | 2.04 | 1 | 0 | acyl chloride | hapten |
dichloroacetic acid
[no description available] | 3.13 | 5 | 0 | monocarboxylic acid;
organochlorine compound | astringent;
marine metabolite |
1,3-dichloro-2-propanol
1,3-dichloro-2-propanol: RN given refers to cpd with specified locants. 1,3-dichloropropan-2-ol : A secondary alcohol that is isopropanol in which one hydrogen of each methyl group is substituted by a chlorine. A liquid at room temperature (melting point -4degreeC, boiling point 174degreeC at 760 mm Hg), it is used as a solvent for hard resins and nitrocellulose. | 2.04 | 1 | 0 | organochlorine compound;
secondary alcohol | cross-linking reagent;
protic solvent |
ethylene dibromide
Ethylene Dibromide: An effective soil fumigant, insecticide, and nematocide. In humans, it causes severe burning of skin and irritation of the eyes and respiratory tract. Prolonged inhalation may cause liver necrosis. It is also used in gasoline. Members of this group have caused liver and lung cancers in rodents. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), 1,2-dibromoethane may reasonably be anticipated to be a carcinogen.. 1,2-dibromoethane : A bromoalkane that is ethane carrying bromo substituents at positions 1 and 2. It is produced by marine algae. | 2.04 | 1 | 0 | bromoalkane;
bromohydrocarbon | algal metabolite;
carcinogenic agent;
fumigant;
marine metabolite;
mouse metabolite;
mutagen |
allyl chloride
[no description available] | 2.04 | 1 | 0 | organochlorine compound | |
ethylene bromohydrin
ethylene bromohydrin: RN given refers to 2-bromo cpd | 2.04 | 1 | 0 | | |
3-Bromo-1-propanol
[no description available] | 2.04 | 1 | 0 | primary alcohol | |
dibromoacetic acid
dibromoacetic acid : A monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are replaced by bromo groups. | 3.16 | 5 | 0 | 2-bromocarboxylic acid;
monocarboxylic acid | apoptosis inducer;
geroprotector;
marine metabolite |
dichloroacetonitrile
dichloroacetonitrile: by-product of water chlorination; structure given in first source | 2.08 | 1 | 0 | aliphatic nitrile | |
chlorine
Chlorine: An element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family. | 2.08 | 1 | 0 | diatomic chlorine;
gas molecular entity | bleaching agent |
2-bromoacrolein
[no description available] | 2.04 | 1 | 0 | | |
phenyl acetate
phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid. | 3.92 | 12 | 0 | benzenes;
phenyl acetates | |
bromates
Bromates: Negative ions or salts derived from bromic acid, HBrO3. | 2.02 | 1 | 0 | bromine oxoanion;
monovalent inorganic anion | |
sodium perchlorate
sodium perchlorate : An inorganic sodium salt comprising equal numbers of sodium and perchlorate ions. | 2.02 | 1 | 0 | inorganic sodium salt | |
bromochloroacetic acid
Keratins: A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.. bromochloroacetic acid : A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by bromine while a second is replaced by chlorine. A low-melting (27.5-31.5degreeC), hygroscopic crystalline solid, it can be formed during the disinfection (by chlorination) of water that contains bromide ions and organic matter, so can occur in drinking water as a byproduct of the disinfection process. | 3.16 | 5 | 0 | 2-bromocarboxylic acid;
monocarboxylic acid;
organochlorine compound | |
1,4-dichloro-2-butene
1,4-dichloro-2-butene: RN given refers to parent cpd without isomeric designation; structure | 2.04 | 1 | 0 | organochlorine compound | |
mitobronitol
Mitobronitol: Brominated analog of MANNITOL which is an antineoplastic agent appearing to act as an alkylating agent. | 2.04 | 1 | 0 | alcohol;
organobromine compound | |
transforming growth factor beta
Transforming Growth Factor beta: A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins. | 2.13 | 1 | 0 | | |