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Ecdysone receptor
A protein that is a translation product of the EcR gene in fruit fly. [PRO:DNx, UniProtKB:P34021]
Synonyms
20-hydroxy-ecdysone receptor;
20E receptor;
EcRH;
Ecdysteroid receptor;
Nuclear receptor subfamily 1 group H member 1
Research
Bioassay Publications (3)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (9)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| ecdysone | Drosophila melanogaster (fruit fly) | IC50 | 2.5704 | 1 | 1 |
| tebufenozide | Drosophila melanogaster (fruit fly) | Ki | 0.2512 | 1 | 1 |
| ponasterone a | Drosophila melanogaster (fruit fly) | IC50 | 0.0013 | 1 | 1 |
| cyasterone | Drosophila melanogaster (fruit fly) | IC50 | 0.0617 | 1 | 1 |
| ecdysterone | Drosophila melanogaster (fruit fly) | IC50 | 0.0457 | 2 | 2 |
| 20,22-dihydroxycholesterol | Drosophila melanogaster (fruit fly) | IC50 | 41.6869 | 1 | 1 |
Drugs with Activation Measurements
Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling.Pest management science, , Volume: 67, Issue:11, 2011
Comparison of the activity of non-steroidal ecdysone agonists between dipteran and lepidopteran insects, using cell-based EcR reporter assays.Pest management science, , Volume: 66, Issue:11, 2010
Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling.Pest management science, , Volume: 67, Issue:11, 2011
Evaluation of hydrogen bonds of ecdysteroids in the ligand-receptor interactions using a protein modeling system.Bioorganic & medicinal chemistry, , Aug-15, Volume: 17, Issue:16, 2009