Page last updated: 2024-08-07 13:27:47

Inositol monophosphatase 1

An inositol monophosphatase 1 that is encoded in the genome of rat. [OMA:P97697, PRO:DNx]

Synonyms

IMP 1;
IMPase 1;
EC 3.1.3.25;
D-galactose 1-phosphate phosphatase;
3.1.3.94;
Inositol-1(or 4)-monophosphatase 1;
Lithium-sensitive myo-inositol monophosphatase A1

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (1159)

Drugs with Potency Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanoic acidRattus norvegicus (Norway rat)Potency5.623410
4-methylumbelliferyl acetateRattus norvegicus (Norway rat)Potency11.220210
diacetylRattus norvegicus (Norway rat)Potency0.010010
gallopamilRattus norvegicus (Norway rat)Potency20.267610
b 844-39Rattus norvegicus (Norway rat)Potency2.238710
1-(3-chlorophenyl)biguanideRattus norvegicus (Norway rat)Potency7.943310
1-palmityl-2-acetylglycerolRattus norvegicus (Norway rat)Potency3.548110
hoe 33342Rattus norvegicus (Norway rat)Potency12.589310
mdl 72222Rattus norvegicus (Norway rat)Potency20.085010
3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octaneRattus norvegicus (Norway rat)Potency0.316210
phenytoinRattus norvegicus (Norway rat)Potency5.011910
5,7-dichlorokynurenic acidRattus norvegicus (Norway rat)Potency12.924420
7,8-dihydroxyflavoneRattus norvegicus (Norway rat)Potency15.848910
8-(4-sulfophenyl)theophyllineRattus norvegicus (Norway rat)Potency10.000010
ag 127Rattus norvegicus (Norway rat)Potency7.943310
rtki cpdRattus norvegicus (Norway rat)Potency7.623710
tyrphostin a23Rattus norvegicus (Norway rat)Potency14.240020
tyrphostin 25Rattus norvegicus (Norway rat)Potency6.350520
albendazoleRattus norvegicus (Norway rat)Potency28.183810
am 580Rattus norvegicus (Norway rat)Potency2.511910
ambenoniumRattus norvegicus (Norway rat)Potency11.220210
theophyllineRattus norvegicus (Norway rat)Potency7.943310
amoxapineRattus norvegicus (Norway rat)Potency17.782810
anisindioneRattus norvegicus (Norway rat)Potency11.220210
antazolineRattus norvegicus (Norway rat)Potency0.501210
2-amino-4-phosphonobutyric acidRattus norvegicus (Norway rat)Potency22.387210
1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid prop-2-ynyl esterRattus norvegicus (Norway rat)Potency1.000010
arecolineRattus norvegicus (Norway rat)Potency3.548110
astemizoleRattus norvegicus (Norway rat)Potency3.162310
aurintricarboxylic acidRattus norvegicus (Norway rat)Potency11.904820
bepridilRattus norvegicus (Norway rat)Potency1.584910
berberineRattus norvegicus (Norway rat)Potency10.430420
bay h 4502Rattus norvegicus (Norway rat)Potency3.162310
cantharidinRattus norvegicus (Norway rat)Potency10.000010
carbetapentaneRattus norvegicus (Norway rat)Potency5.011910
carbonyl cyanide m-chlorophenyl hydrazoneRattus norvegicus (Norway rat)Potency3.548110
cgp 37157Rattus norvegicus (Norway rat)Potency3.162310
chelerythrineRattus norvegicus (Norway rat)Potency5.011910
clofibrateRattus norvegicus (Norway rat)Potency14.125410
clomipramineRattus norvegicus (Norway rat)Potency0.446710
clonidineRattus norvegicus (Norway rat)Potency31.622810
4-chloro-N-(2,6-dimethyl-1-piperidinyl)-3-sulfamoylbenzamideRattus norvegicus (Norway rat)Potency3.162310
cyclobenzaprineRattus norvegicus (Norway rat)Potency0.316210
dequaliniumRattus norvegicus (Norway rat)Potency10.000010
dilazepRattus norvegicus (Norway rat)Potency31.622810
n,n-di-n-propyldopamineRattus norvegicus (Norway rat)Potency0.031610
dipyridamoleRattus norvegicus (Norway rat)Potency19.702010
disulfiramRattus norvegicus (Norway rat)Potency15.848910
domperidoneRattus norvegicus (Norway rat)Potency7.079510
dyclonineRattus norvegicus (Norway rat)Potency0.001310
embelinRattus norvegicus (Norway rat)Potency1.584910
emodinRattus norvegicus (Norway rat)Potency31.622810
carbonyl cyanide p-trifluoromethoxyphenylhydrazoneRattus norvegicus (Norway rat)Potency3.981110
fluphenazineRattus norvegicus (Norway rat)Potency7.079510
furafyllineRattus norvegicus (Norway rat)Potency0.398110
vanoxerineRattus norvegicus (Norway rat)Potency7.600610
gbr 12935Rattus norvegicus (Norway rat)Potency14.432610
gliclazideRattus norvegicus (Norway rat)Potency5.011910
glyburideRattus norvegicus (Norway rat)Potency31.622810
go 6976Rattus norvegicus (Norway rat)Potency3.548110
gossypolRattus norvegicus (Norway rat)Potency12.589310
harmalineRattus norvegicus (Norway rat)Potency10.000010
harmalolRattus norvegicus (Norway rat)Potency22.874120
hexachloropheneRattus norvegicus (Norway rat)Potency17.782810
velnacrineRattus norvegicus (Norway rat)Potency0.501210
hydroxyureaRattus norvegicus (Norway rat)Potency28.183810
atropine sulfateRattus norvegicus (Norway rat)Potency14.125410
hypericinRattus norvegicus (Norway rat)Potency11.294710
ici 118551Rattus norvegicus (Norway rat)Potency11.220210
ici 204448Rattus norvegicus (Norway rat)Potency2.511910
indigotindisulfonateRattus norvegicus (Norway rat)Potency28.183810
indirubin-3'-monoximeRattus norvegicus (Norway rat)Potency12.589310
3-hydroxy-2-phenylpropanoic acid (8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl) esterRattus norvegicus (Norway rat)Potency1.000010
ketotifenRattus norvegicus (Norway rat)Potency6.119410
2-amino-3-phosphonopropionic acidRattus norvegicus (Norway rat)Potency2.818410
lapacholRattus norvegicus (Norway rat)Potency12.589310
beta-lapachoneRattus norvegicus (Norway rat)Potency11.220210
lobelineRattus norvegicus (Norway rat)Potency2.511910
loperamideRattus norvegicus (Norway rat)Potency3.162310
loratadineRattus norvegicus (Norway rat)Potency0.446710
6-anilino-5,8-quinolinedioneRattus norvegicus (Norway rat)Potency1.584910
maprotilineRattus norvegicus (Norway rat)Potency7.943320
mebendazoleRattus norvegicus (Norway rat)Potency28.183810
vitamin k 3Rattus norvegicus (Norway rat)Potency4.564010
methiothepinRattus norvegicus (Norway rat)Potency3.548110
methoxychlorRattus norvegicus (Norway rat)Potency39.810710
nocodazoleRattus norvegicus (Norway rat)Potency28.183810
3,7-bis(dimethylamino)phenothiazin-5-iumRattus norvegicus (Norway rat)Potency28.183810
5-methylfurtrethoniumRattus norvegicus (Norway rat)Potency10.000010
mianserinRattus norvegicus (Norway rat)Potency1.995310
minaprineRattus norvegicus (Norway rat)Potency0.002510
minoxidilRattus norvegicus (Norway rat)Potency0.891310
mitoxantroneRattus norvegicus (Norway rat)Potency10.000010
deoxyepinephrineRattus norvegicus (Norway rat)Potency0.025110
etoposide phosphateRattus norvegicus (Norway rat)Potency10.000010
naftopidilRattus norvegicus (Norway rat)Potency2.511910
nicardipineRattus norvegicus (Norway rat)Potency12.589310
nifedipineRattus norvegicus (Norway rat)Potency10.451010
nitrendipineRattus norvegicus (Norway rat)Potency0.501210
nortriptylineRattus norvegicus (Norway rat)Potency1.995310
5-nitro-2-(3-phenylpropylamino)benzoic acidRattus norvegicus (Norway rat)Potency19.952610
oxolinic acidRattus norvegicus (Norway rat)Potency7.943310
palmidrolRattus norvegicus (Norway rat)Potency10.000010
papaverineRattus norvegicus (Norway rat)Potency17.782810
1,7-dimethylxanthineRattus norvegicus (Norway rat)Potency31.622810
pentoxifyllineRattus norvegicus (Norway rat)Potency0.025110
pirenzepineRattus norvegicus (Norway rat)Potency4.679610
pridinolRattus norvegicus (Norway rat)Potency0.316210
promazineRattus norvegicus (Norway rat)Potency3.981110
promethazineRattus norvegicus (Norway rat)Potency1.412510
propidiumRattus norvegicus (Norway rat)Potency28.183810
protopineRattus norvegicus (Norway rat)Potency11.220210
pyridostigmineRattus norvegicus (Norway rat)Potency25.118910
1,2,5,8-tetrahydroxy anthraquinoneRattus norvegicus (Norway rat)Potency12.589310
rofecoxibRattus norvegicus (Norway rat)Potency8.912510
sanguinarineRattus norvegicus (Norway rat)Potency10.000010
sb 206553Rattus norvegicus (Norway rat)Potency28.183810
dpi 201-106Rattus norvegicus (Norway rat)Potency11.220210
4-[6-amino-3-(4-methoxyphenyl)-1-pyridazin-1-iumyl]butanoic acidRattus norvegicus (Norway rat)Potency6.309610
streptonigrinRattus norvegicus (Norway rat)Potency14.125410
suprofenRattus norvegicus (Norway rat)Potency5.011910
suraminRattus norvegicus (Norway rat)Potency3.162310
1,4-bis(2-(3,5-dichloropyridyloxy))benzeneRattus norvegicus (Norway rat)Potency1.412510
8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoateRattus norvegicus (Norway rat)Potency5.250610
n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamineRattus norvegicus (Norway rat)Potency4.466810
triamtereneRattus norvegicus (Norway rat)Potency11.904810
trifluoperazineRattus norvegicus (Norway rat)Potency1.412510
ics 205-930Rattus norvegicus (Norway rat)Potency31.622810
tyramineRattus norvegicus (Norway rat)Potency31.622810
tyrphostin a9Rattus norvegicus (Norway rat)Potency2.241210
u 99194Rattus norvegicus (Norway rat)Potency12.589310
wb 4101Rattus norvegicus (Norway rat)Potency2.511910
zm 336372Rattus norvegicus (Norway rat)Potency0.316210
estroneRattus norvegicus (Norway rat)Potency3.548110
promazine hydrochlorideRattus norvegicus (Norway rat)Potency0.794310
1,2,5,6-dibenzanthraceneRattus norvegicus (Norway rat)Potency12.589310
cystamine dihydrochlorideRattus norvegicus (Norway rat)Potency5.623410
promethazine hydrochlorideRattus norvegicus (Norway rat)Potency0.891310
adenosine diphosphateRattus norvegicus (Norway rat)Potency28.183810
papaverine hydrochlorideRattus norvegicus (Norway rat)Potency18.169610
methylene blueRattus norvegicus (Norway rat)Potency1.995310
uridine triphosphateRattus norvegicus (Norway rat)Potency28.183810
dimethylformamideRattus norvegicus (Norway rat)Potency6.309610
quinacrine monohydrochlorideRattus norvegicus (Norway rat)Potency4.601110
chlorpromazine hydrochlorideRattus norvegicus (Norway rat)Potency7.943310
alizarinRattus norvegicus (Norway rat)Potency13.675820
n,n'-diphenyl-4-phenylenediamineRattus norvegicus (Norway rat)Potency28.183810
mepenzolate bromideRattus norvegicus (Norway rat)Potency0.251210
dicumyl peroxideRattus norvegicus (Norway rat)Potency28.183810
purpurinRattus norvegicus (Norway rat)Potency10.000010
rotenoneRattus norvegicus (Norway rat)Potency28.370810
9,10-phenanthrenequinoneRattus norvegicus (Norway rat)Potency17.782810
1-(2-pyridylazo)-2-naphtholRattus norvegicus (Norway rat)Potency8.912510
acriflavine chlorideRattus norvegicus (Norway rat)Potency11.220210
michler's ketoneRattus norvegicus (Norway rat)Potency1.122010
2-methyl-4-chlorophenoxyacetic acidRattus norvegicus (Norway rat)Potency0.079410
dimethyl-4-phenylenediamineRattus norvegicus (Norway rat)Potency14.125410
tetramethylphenylenediamineRattus norvegicus (Norway rat)Potency14.125410
n-isopropyl-n-phenyl-4-phenylenediamineRattus norvegicus (Norway rat)Potency31.622810
allyl glycidyl etherRattus norvegicus (Norway rat)Potency14.125410
thiodipropionic acidRattus norvegicus (Norway rat)Potency0.354810
chloranilRattus norvegicus (Norway rat)Potency16.903610
dianisidineRattus norvegicus (Norway rat)Potency15.848910
benzethonium chlorideRattus norvegicus (Norway rat)Potency11.220210
piperidolate hydrochlorideRattus norvegicus (Norway rat)Potency2.238710
3-amino-9-ethylcarbazoleRattus norvegicus (Norway rat)Potency0.063110
methapyrilene hydrochlorideRattus norvegicus (Norway rat)Potency12.589310
4-nitrosodimethylanilineRattus norvegicus (Norway rat)Potency11.220210
benzyl acetateRattus norvegicus (Norway rat)Potency6.309610
diphenhydramine hydrochlorideRattus norvegicus (Norway rat)Potency0.891310
propantheline bromideRattus norvegicus (Norway rat)Potency3.162310
benzoquinoniumRattus norvegicus (Norway rat)Potency11.220210
N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamineRattus norvegicus (Norway rat)Potency22.387210
indirubinRattus norvegicus (Norway rat)Potency3.548110
plumbaginRattus norvegicus (Norway rat)Potency13.557110
indigoRattus norvegicus (Norway rat)Potency3.162310
cytisineRattus norvegicus (Norway rat)Potency3.162310
hematoxylinRattus norvegicus (Norway rat)Potency4.466810
dequalinium chlorideRattus norvegicus (Norway rat)Potency3.981110
dimenhydrinateRattus norvegicus (Norway rat)Potency3.548110
domiphen bromideRattus norvegicus (Norway rat)Potency1.412510
gentian violetRattus norvegicus (Norway rat)Potency11.294710
thiphenamilRattus norvegicus (Norway rat)Potency7.079510
amitriptyline hydrochlorideRattus norvegicus (Norway rat)Potency3.162310
doxylamine succinateRattus norvegicus (Norway rat)Potency1.995310
aminacrineRattus norvegicus (Norway rat)Potency1.995310
Berberine chloride (TN)Rattus norvegicus (Norway rat)Potency3.981110
malononitrile dimerRattus norvegicus (Norway rat)Potency11.220210
3-methoxycatecholRattus norvegicus (Norway rat)Potency10.000010
carmineRattus norvegicus (Norway rat)Potency20.116220
guaiacoxyacetic acidRattus norvegicus (Norway rat)Potency0.794310
tetrachloroisophthalonitrileRattus norvegicus (Norway rat)Potency25.118910
clothiapineRattus norvegicus (Norway rat)Potency1.995310
pimozideRattus norvegicus (Norway rat)Potency5.004020
1,5-naphthalenediamineRattus norvegicus (Norway rat)Potency2.511910
doxifluridineRattus norvegicus (Norway rat)Potency11.220210
1,6-bismaleimidohexaneRattus norvegicus (Norway rat)Potency28.183810
cyclogylRattus norvegicus (Norway rat)Potency0.398110
cyclobenzaprine hydrochlorideRattus norvegicus (Norway rat)Potency0.891310
methylene bis(thiocyanate)Rattus norvegicus (Norway rat)Potency12.589310
coralyneRattus norvegicus (Norway rat)Potency2.238710
propionylpromazine hydrochlorideRattus norvegicus (Norway rat)Potency6.309610
5,7-dimethyl-(1,2,4)triazolo(1,5-a)pyrimidineRattus norvegicus (Norway rat)Potency3.548110
camptothecinRattus norvegicus (Norway rat)Potency0.316210
terbufosRattus norvegicus (Norway rat)Potency28.183810
n-acetylamphetamineRattus norvegicus (Norway rat)Potency31.622810
pizotylineRattus norvegicus (Norway rat)Potency10.000010
daunorubicinRattus norvegicus (Norway rat)Potency12.589310
cetylpyridinium chloride anhydrousRattus norvegicus (Norway rat)Potency2.238710
2-tert-butylbenzimidazoleRattus norvegicus (Norway rat)Potency1.122010
carbidopaRattus norvegicus (Norway rat)Potency31.622810
moricizine hydrochlorideRattus norvegicus (Norway rat)Potency5.011910
proroxan hydrochlorideRattus norvegicus (Norway rat)Potency25.118910
hc blue no. 2Rattus norvegicus (Norway rat)Potency11.220210
idarubicinRattus norvegicus (Norway rat)Potency1.995310
N-[4-(dimethylamino)phenyl]-3,4,5-trimethoxybenzamideRattus norvegicus (Norway rat)Potency15.848910
tiotidineRattus norvegicus (Norway rat)Potency2.238710
mitoxantrone hydrochlorideRattus norvegicus (Norway rat)Potency2.008510
atomoxetineRattus norvegicus (Norway rat)Potency10.000010
lisofyllineRattus norvegicus (Norway rat)Potency0.501210
topotecan hydrochlorideRattus norvegicus (Norway rat)Potency28.183810
eliprodilRattus norvegicus (Norway rat)Potency1.584910
aripiprazoleRattus norvegicus (Norway rat)Potency7.943310
aptiganel hydrochlorideRattus norvegicus (Norway rat)Potency14.125410
daunorubicin hydrochlorideRattus norvegicus (Norway rat)Potency13.357410
desipramine hydrochlorideRattus norvegicus (Norway rat)Potency17.782810
thioridazine hydrochlorideRattus norvegicus (Norway rat)Potency17.585510
diphenylpyraline hydrochlorideRattus norvegicus (Norway rat)Potency2.238710
trifluoperazine hydrochlorideRattus norvegicus (Norway rat)Potency3.162310
siquilRattus norvegicus (Norway rat)Potency1.778310
oxymetazoline hydrochlorideRattus norvegicus (Norway rat)Potency5.011910
caramiphenRattus norvegicus (Norway rat)Potency14.125410
fluphenazine hydrochlorideRattus norvegicus (Norway rat)Potency11.220210
2,6-dimethoxy-1,4-benzoquinoneRattus norvegicus (Norway rat)Potency31.622810
N-benzoylanthranilic acidRattus norvegicus (Norway rat)Potency1.258910
clomipramine hydrochlorideRattus norvegicus (Norway rat)Potency0.446710
econazole nitrateRattus norvegicus (Norway rat)Potency31.622810
masoprocolRattus norvegicus (Norway rat)Potency19.952610
loxapine succinateRattus norvegicus (Norway rat)Potency2.289210
maprotiline hydrochlorideRattus norvegicus (Norway rat)Potency4.916910
opipramol hydrochlorideRattus norvegicus (Norway rat)Potency19.952610
acetylisoniazidRattus norvegicus (Norway rat)Potency0.398110
jatrorrhizineRattus norvegicus (Norway rat)Potency12.589310
paceinRattus norvegicus (Norway rat)Potency1.258910
methyl fluorone blackRattus norvegicus (Norway rat)Potency11.904820
2,6-dimethylphenylphthalimideRattus norvegicus (Norway rat)Potency10.000010
agroclavineRattus norvegicus (Norway rat)Potency31.622810
Dibenzyl phosphateRattus norvegicus (Norway rat)Potency11.220210
4'-methoxyflavoneRattus norvegicus (Norway rat)Potency28.183810
orphenadrine citrateRattus norvegicus (Norway rat)Potency11.220210
fentanyl isothiocyanateRattus norvegicus (Norway rat)Potency15.848910
nicotineRattus norvegicus (Norway rat)Potency28.183810
carbetapentane citrateRattus norvegicus (Norway rat)Potency0.794310
prochlorperazine edisylate saltRattus norvegicus (Norway rat)Potency11.220210
adenosine 5'-methylenediphosphateRattus norvegicus (Norway rat)Potency25.118910
levobupivacaineRattus norvegicus (Norway rat)Potency0.010010
2-methyl-4'-(methylthio)-2-morpholinopropiophenoneRattus norvegicus (Norway rat)Potency11.220210
n-(4,4-diphenyl-3-butenyl)nipecotic acidRattus norvegicus (Norway rat)Potency8.912510
norcantharidinRattus norvegicus (Norway rat)Potency28.183810
10-hydroxycamptothecinRattus norvegicus (Norway rat)Potency10.610110
oxoglaucineRattus norvegicus (Norway rat)Potency12.589310
benzpiperyloneRattus norvegicus (Norway rat)Potency2.511910
7-amino-4-trifluoromethylcoumarinRattus norvegicus (Norway rat)Potency31.622810
3,5-dihydroxyphenylglycineRattus norvegicus (Norway rat)Potency5.011910
1-hexadecyl-2-acetyl-glycero-3-phosphocholineRattus norvegicus (Norway rat)Potency2.238710
3,4-dimethoxydalbergioneRattus norvegicus (Norway rat)Potency10.000010
1-[4-[2-hydroxy-3-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]propoxy]phenyl]-1-propanoneRattus norvegicus (Norway rat)Potency17.782810
eserolineRattus norvegicus (Norway rat)Potency28.183810
desloratadineRattus norvegicus (Norway rat)Potency1.756010
bd 1008Rattus norvegicus (Norway rat)Potency28.183810
2-phenyl-3-(n,n-dimethylaminopropyl)-1,3-thiazolidin-4-oneRattus norvegicus (Norway rat)Potency19.952610
gr 55562Rattus norvegicus (Norway rat)Potency14.125410
sr 2640Rattus norvegicus (Norway rat)Potency28.183810
2-(4-ethoxybenzyl)-1-diethylaminoethyl-5-isothiocyanatobenzimidazoleRattus norvegicus (Norway rat)Potency25.118910
(hydroxy-2-naphthalenylmethyl)phosphonic acidRattus norvegicus (Norway rat)Potency0.501210
aq-ra 741Rattus norvegicus (Norway rat)Potency0.707910
sr 57227aRattus norvegicus (Norway rat)Potency0.562310
4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazineRattus norvegicus (Norway rat)Potency31.622810
3,5-bis(trifluoromethyl)benzyl n-acetyltryptophanRattus norvegicus (Norway rat)Potency6.309610
n-(n-benzylpiperidin-4-yl)-4-iodobenzamideRattus norvegicus (Norway rat)Potency8.912510
isoteolinRattus norvegicus (Norway rat)Potency22.874120
sg 209Rattus norvegicus (Norway rat)Potency1.000010
3',4'-dihydroxyflavoneRattus norvegicus (Norway rat)Potency31.622810
harmalol hydrochlorideRattus norvegicus (Norway rat)Potency8.912510
nsc-141549Rattus norvegicus (Norway rat)Potency5.623410
oxidopamine hydrochlorideRattus norvegicus (Norway rat)Potency15.848910
cyc 202Rattus norvegicus (Norway rat)Potency2.818410
pridinol mesylateRattus norvegicus (Norway rat)Potency31.622810
rufloxacin hydrochlorideRattus norvegicus (Norway rat)Potency16.815820
sch 58261Rattus norvegicus (Norway rat)Potency28.183810
n-methyl-n-(1-phenyl-2-(1-pyrrolidinyl)ethyl)phenylacetamideRattus norvegicus (Norway rat)Potency14.125410
sb 205384Rattus norvegicus (Norway rat)Potency28.183810
procyclidine hydrochlorideRattus norvegicus (Norway rat)Potency0.251210
2-amino-5-phenyl-1,3,4-thiadiazoleRattus norvegicus (Norway rat)Potency31.622810
nsc 95397Rattus norvegicus (Norway rat)Potency11.427820
wortmanninRattus norvegicus (Norway rat)Potency28.183810
1-oxo-2-benzothiopyran-3-carboxylic acid methyl esterRattus norvegicus (Norway rat)Potency5.011910
6-dimethylaminopurine arabinosideRattus norvegicus (Norway rat)Potency2.238710
nsc 663284Rattus norvegicus (Norway rat)Potency10.000010
mrs 1220Rattus norvegicus (Norway rat)Potency29.903320
4-(4-chlorophenyl)-1-methyl-2-(methylthio)-6-oxo-5-pyrimidinecarbonitrileRattus norvegicus (Norway rat)Potency28.183810
2H-pyrazolo[4,3-b]quinoxalin-3-amineRattus norvegicus (Norway rat)Potency13.534620
D-leucineRattus norvegicus (Norway rat)Potency5.011910
tosylphenylalanyl chloromethyl ketoneRattus norvegicus (Norway rat)Potency12.589310
hyperforinRattus norvegicus (Norway rat)Potency1.778310
metyrosineRattus norvegicus (Norway rat)Potency3.981110
ochratoxin aRattus norvegicus (Norway rat)Potency17.782810
acetylleucyl-leucyl-norleucinalRattus norvegicus (Norway rat)Potency0.501210
carubicinRattus norvegicus (Norway rat)Potency11.220210
tolterodineRattus norvegicus (Norway rat)Potency12.589310
doxorubicin hydrochlorideRattus norvegicus (Norway rat)Potency21.154610
resveratrolRattus norvegicus (Norway rat)Potency10.000010
docosahexaenoateRattus norvegicus (Norway rat)Potency31.622810
diethylstilbestrolRattus norvegicus (Norway rat)Potency5.011910
6-bromoindirubin-3'-oximeRattus norvegicus (Norway rat)Potency12.589310
shikoninRattus norvegicus (Norway rat)Potency7.079510
riboflavinRattus norvegicus (Norway rat)Potency10.000010
dimethyloxalylglycineRattus norvegicus (Norway rat)Potency0.398110
3-(3,5-dimethyl-1-pyrazolyl)-1,2-benzothiazole 1,1-dioxideRattus norvegicus (Norway rat)Potency6.309610
bd 1063Rattus norvegicus (Norway rat)Potency10.000010
2-(2-phenoxyethylsulfonyl)-1H-benzimidazoleRattus norvegicus (Norway rat)Potency5.623410
9-carbazolyl-(4-methylphenyl)methanoneRattus norvegicus (Norway rat)Potency22.387210
2-amino-3-cyano-5,6,7,8-tetrahydroquinoline-4-carboxylic acid methyl esterRattus norvegicus (Norway rat)Potency25.118910
2-chlorothioxanthen-9-oneRattus norvegicus (Norway rat)Potency31.622810
3-(4-pyridyl)-1h-indoleRattus norvegicus (Norway rat)Potency0.100010
3-[[2-[[4-ethyl-5-[(4-methylanilino)methyl]-1,2,4-triazol-3-yl]thio]-1-oxoethyl]amino]benzoic acid ethyl esterRattus norvegicus (Norway rat)Potency0.022410
2-[[5-[4-(1-piperidinylsulfonyl)phenyl]-1H-1,2,4-triazol-3-yl]thio]-N-(2-thiazolyl)acetamideRattus norvegicus (Norway rat)Potency19.952610
1-(2,3-dihydroindol-1-yl)-2-[(5,5-dimethyl-6H-[1,2,4]triazolo[3,4-a]isoquinolin-3-yl)thio]ethanoneRattus norvegicus (Norway rat)Potency11.220210
3-amino-N-cyclopentyl-6-thiophen-2-yl-2-thieno[2,3-b]pyridinecarboxamideRattus norvegicus (Norway rat)Potency17.488220
N-[1-[(4-methylphenyl)methyl]-2-benzimidazolyl]-2-furancarboxamideRattus norvegicus (Norway rat)Potency3.162310
N-[2-(5-chloro-2-methoxyanilino)-2-oxoethyl]-N-cyclohexyl-2-furancarboxamideRattus norvegicus (Norway rat)Potency1.995310
5-(diethylsulfamoyl)-3-hydroxy-2-naphthalenecarboxylic acidRattus norvegicus (Norway rat)Potency12.589310
3-[(1-tert-butyl-5-tetrazolyl)-[2-furanylmethyl(2-oxolanylmethyl)amino]methyl]-6-methoxy-1H-quinolin-2-oneRattus norvegicus (Norway rat)Potency15.848910
2-[cyclohexyl-(2,4,6-trimethylphenyl)sulfonylamino]-N-(3-pyridinylmethyl)acetamideRattus norvegicus (Norway rat)Potency31.622810
6-ethyl-3-[[[1-(2-furanylmethyl)-5-tetrazolyl]methyl-(phenylmethyl)amino]methyl]-1H-quinolin-2-oneRattus norvegicus (Norway rat)Potency3.981110
N-[2-methyl-4-oxo-3-(phenylmethyl)-7-(1-piperidinyl)-6-quinazolinyl]-3-pyridinecarboxamideRattus norvegicus (Norway rat)Potency22.387210
11-[2-(4-morpholinyl)ethylamino]-7,8,9,10-tetrahydrobenzimidazolo[1,2-b]isoquinoline-6-carbonitrileRattus norvegicus (Norway rat)Potency1.258910
2-(4-bromophenyl)-5-(2-methylphenyl)-1,3,4-oxadiazoleRattus norvegicus (Norway rat)Potency28.183810
3-(benzenesulfonyl)-2-imino-1-(2-oxolanylmethyl)-5-dipyrido[1,2-d-3',4'-f]pyrimidinoneRattus norvegicus (Norway rat)Potency31.622810
2-(1,3-benzodioxol-5-ylamino)-N-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetamideRattus norvegicus (Norway rat)Potency17.782810
2-(1-benzimidazolylmethyl)-5-[(4-chlorophenyl)methylthio]-1,3,4-oxadiazoleRattus norvegicus (Norway rat)Potency0.354810
2-methoxy-N-methyl-N-[5-(2-pyridinyl)-1,3,4-thiadiazol-2-yl]acetamideRattus norvegicus (Norway rat)Potency31.622810
2-(N-[2-(1-benzotriazolyl)-1-oxoethyl]-4-methylanilino)-N-(2-furanylmethyl)-2-(3-pyridinyl)acetamideRattus norvegicus (Norway rat)Potency3.162310
N-[4-[4-[[1-oxo-2-(1-pyrrolidinyl)ethyl]amino]phenoxy]phenyl]-2-(1-pyrrolidinyl)acetamideRattus norvegicus (Norway rat)Potency4.466810
3-[1-azepanyl-[1-(phenylmethyl)-5-tetrazolyl]methyl]-7-methoxy-1H-quinolin-2-oneRattus norvegicus (Norway rat)Potency6.309610
N-[4-[1-(benzenesulfonyl)-2,3-dihydroindol-5-yl]-2-thiazolyl]-2-(4-morpholinyl)acetamideRattus norvegicus (Norway rat)Potency12.589310
5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-[(2-fluorophenoxy)methyl]-4-oxazolecarbonitrileRattus norvegicus (Norway rat)Potency3.981110
N-cyclopentyl-2-[2-oxolanylmethyl-(1-oxo-2-thiophen-2-ylethyl)amino]-2-thiophen-2-ylacetamideRattus norvegicus (Norway rat)Potency0.501210
[3-[3-(5-methyl-2-furanyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-phenylmethanoneRattus norvegicus (Norway rat)Potency1.995310
3-[[2-[[5-[(4-cyanophenoxy)methyl]-4-phenyl-1,2,4-triazol-3-yl]thio]-1-oxoethyl]amino]benzoic acid methyl esterRattus norvegicus (Norway rat)Potency28.183810
N-(1,3-benzodioxol-5-yl)-1-[(4-fluorophenyl)methyl]-4-triazolecarboxamideRattus norvegicus (Norway rat)Potency12.589310
2-[(3-ethyl-2-quinolinyl)thio]-N-(5-methyl-3-isoxazolyl)acetamideRattus norvegicus (Norway rat)Potency10.000010
N-[2-(2-ethyl-5-tetrazolyl)phenyl]-3-(1-tetrazolyl)benzamideRattus norvegicus (Norway rat)Potency28.183810
1-(4-fluorophenyl)-4-[[1-(2-phenylethyl)-5-tetrazolyl]-thiophen-2-ylmethyl]piperazineRattus norvegicus (Norway rat)Potency0.794310
N-(1,3-benzodioxol-5-yl)-1-[4-(4-morpholinylsulfonyl)phenyl]-4-piperidinecarboxamideRattus norvegicus (Norway rat)Potency17.246720
N-(4-chlorophenyl)-4-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinecarboxamideRattus norvegicus (Norway rat)Potency31.622810
2-[[(4-methyl-5-thieno[3,2-b]pyrrolyl)-oxomethyl]amino]benzoic acid methyl esterRattus norvegicus (Norway rat)Potency39.810710
2-[(1,3-dimethyl-2,6-dioxo-7-propyl-8-purinyl)thio]-N-[2-(1-piperidinyl)phenyl]acetamideRattus norvegicus (Norway rat)Potency14.125410
N-[1-(2-methoxyphenyl)-5-benzimidazolyl]benzenesulfonamideRattus norvegicus (Norway rat)Potency22.387210
1-(4-chlorophenyl)-1-cyclohexyl-3-(4-morpholinyl)-1-propanolRattus norvegicus (Norway rat)Potency2.238710
6-chloro-2-[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-piperidinyl]-1H-benzimidazoleRattus norvegicus (Norway rat)Potency10.000010
2-methyl-4-[2-oxo-2-(2-phenylethylamino)ethyl]-5-thieno[3,2-b]pyrrolecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency28.183810
6,6-dimethyl-5,8-dihydropyrano[4,5]thieno[1,2-c]pyrimidin-4-amineRattus norvegicus (Norway rat)Potency0.707910
3-(3-chlorophenyl)-1-(3-hydroxypropyl)-1-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]ureaRattus norvegicus (Norway rat)Potency0.025110
4,5-dimethyl-2-[[oxo(thiophen-2-yl)methyl]amino]-3-thiophenecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency31.622810
4-(2-benzamidoethylamino)-1-piperidinecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency7.943310
1-[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-piperidinyl]-5-fluorobenzotriazoleRattus norvegicus (Norway rat)Potency0.007110
2-[(2,3-dimethyl-7,8,9,10-tetrahydrophenanthridin-6-yl)thio]-N-(4-methyl-1,2,5-oxadiazol-3-yl)acetamideRattus norvegicus (Norway rat)Potency6.309610
4-methyl-N-(pyridin-4-ylmethyl)benzenesulfonamideRattus norvegicus (Norway rat)Potency1.000010
N-methyl-N-[5-(3-pyridinyl)-1,3,4-thiadiazol-2-yl]-3-pyridinecarboxamideRattus norvegicus (Norway rat)Potency2.511910
N-[2,5-diethoxy-4-[[oxo-(3,4,5-trimethoxyphenyl)methyl]amino]phenyl]-2-furancarboxamideRattus norvegicus (Norway rat)Potency0.031610
N-(1,3-benzodioxol-5-yl)-2-[4-(4-phenyl-2-thiazolyl)-1-piperazinyl]acetamideRattus norvegicus (Norway rat)Potency7.769020
4-[3-(1,3-dioxo-2-isoindolyl)propylamino]-2-methylisoindole-1,3-dioneRattus norvegicus (Norway rat)Potency28.183810
2-[(2-ethyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)thio]-N-(2-furanylmethyl)acetamideRattus norvegicus (Norway rat)Potency39.810710
3-fluoro-N-[1-[2-[(2-fluorophenyl)methylamino]-2-oxoethyl]-4-piperidinyl]benzamideRattus norvegicus (Norway rat)Potency0.251210
1-[1-[(4-hydroxy-1-piperidinyl)-oxomethyl]cyclohexyl]-3-(2-methoxyphenyl)ureaRattus norvegicus (Norway rat)Potency0.039810
2-(2,5-dimethoxyphenyl)-5-[4-(4-methoxyphenyl)phenyl]-1,3,4-oxadiazoleRattus norvegicus (Norway rat)Potency22.387210
3-[3,4-dihydro-1H-isoquinolin-2-yl-[1-(2-oxolanylmethyl)-5-tetrazolyl]methyl]-6-methyl-1H-quinolin-2-oneRattus norvegicus (Norway rat)Potency3.162310
N-(4-fluorophenyl)-2-[[5-(2-fluorophenyl)-1,3,4-oxadiazol-2-yl]thio]-N-[(4-methoxyphenyl)methyl]acetamideRattus norvegicus (Norway rat)Potency12.589310
N-(2-methylphenyl)-2-[5-[4-(4-morpholinyl)phenyl]-2-tetrazolyl]acetamideRattus norvegicus (Norway rat)Potency10.000010
4-(3-methyl-5-isoxazolyl)-5-phenylcyclohexane-1,3-dioneRattus norvegicus (Norway rat)Potency31.622810
3-cyclohexyl-1-[(6,7-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-1-[3-(4-morpholinyl)propyl]ureaRattus norvegicus (Norway rat)Potency11.220210
N-[(1-cyclohexyl-5-tetrazolyl)-thiophen-2-ylmethyl]-N-(phenylmethyl)ethanamineRattus norvegicus (Norway rat)Potency6.309610
2-(2-cyanophenoxy)-N-[2-[cyclopropyl(oxo)methyl]-3-benzofuranyl]acetamideRattus norvegicus (Norway rat)Potency8.912510
2-thiophenecarboxylic acid [3-methyl-1-oxo-1-(thiophen-2-ylmethylamino)butan-2-yl] esterRattus norvegicus (Norway rat)Potency25.118910
6-[(2-fluorophenyl)methyl]-2,4-dimethyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinoneRattus norvegicus (Norway rat)Potency31.622810
2-[[4-methyl-5-[4-(4-morpholinylsulfonyl)phenyl]-1,2,4-triazol-3-yl]thio]-N-(4-methylphenyl)acetamideRattus norvegicus (Norway rat)Potency25.118910
4-methyl-5-thieno[3,2-b]pyrrolecarboxylic acid [2-oxo-2-(thiophen-2-ylmethylamino)ethyl] esterRattus norvegicus (Norway rat)Potency7.220820
2-[[2-(3-methyl-2-methylimino-4-oxo-5-thiazolidinyl)-1-oxoethyl]amino]benzoic acid ethyl esterRattus norvegicus (Norway rat)Potency5.011910
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(thiophen-2-ylmethyl)-2,1,3-benzothiadiazole-4-sulfonamideRattus norvegicus (Norway rat)Potency3.981110
1-[5-(2-amino-5-methyl-4-thiazolyl)-2,3-dihydroindol-1-yl]-1-butanoneRattus norvegicus (Norway rat)Potency3.981110
N-[4-(diethylsulfamoyl)phenyl]-2-(2-oxo-1,3-benzothiazol-3-yl)acetamideRattus norvegicus (Norway rat)Potency1.258910
1-[(1-cyclopentyl-5-tetrazolyl)-thiophen-2-ylmethyl]-4-(2-methoxyphenyl)piperazineRattus norvegicus (Norway rat)Potency28.183810
2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thio]-1-(4-phenyl-1-piperazinyl)ethanoneRattus norvegicus (Norway rat)Potency11.220210
2-[[5-[[2-(3-chloroanilino)-4-thiazolyl]methyl]-4-(3-methoxypropyl)-1,2,4-triazol-3-yl]thio]acetic acid methyl esterRattus norvegicus (Norway rat)Potency0.794310
2-(3,5-dimethyl-1-pyrazolyl)-N,6-dimethyl-4-pyrimidinamineRattus norvegicus (Norway rat)Potency25.118910
2-(2-methyl-1H-indol-3-yl)ethanolRattus norvegicus (Norway rat)Potency28.183810
5-[4-morpholinyl(oxo)methyl]-2-pyranoneRattus norvegicus (Norway rat)Potency5.011910
2-cyano-N-(2-furanylmethyl)-2-[3-(4-morpholinyl)-2-quinoxalinyl]acetamideRattus norvegicus (Norway rat)Potency31.622810
2-[[3-cyano-4-(2-furanyl)-5,6,7,8-tetrahydroquinolin-2-yl]thio]-N-(2-methylphenyl)acetamideRattus norvegicus (Norway rat)Potency10.000010
N-[1-(1-hexyl-2-benzimidazolyl)ethyl]-2-furancarboxamideRattus norvegicus (Norway rat)Potency17.782810
Thieno[3,2-b]thiophene-2-carboxylic acidRattus norvegicus (Norway rat)Potency22.106020
2-cyano-2-[3-[4-(phenylmethyl)-1-piperazinyl]-2-quinoxalinyl]acetic acid 2-methoxyethyl esterRattus norvegicus (Norway rat)Potency10.000010
3-[[2-(4-methyl-1-piperazinyl)-1-oxoethyl]amino]-2-benzofurancarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency12.589310
2-[(6-amino-3,5-dicyano-4-thiophen-2-yl-2-pyridinyl)thio]-N-(2-phenylethyl)acetamideRattus norvegicus (Norway rat)Potency24.068220
2-(4-chlorophenyl)-5-(methylamino)-4-oxazolecarbonitrileRattus norvegicus (Norway rat)Potency5.623410
5-[(3-ethoxycarbonyl-4-thiophen-2-yl-2-thiophenyl)amino]-5-oxopentanoic acidRattus norvegicus (Norway rat)Potency14.976320
5-bromo-3-ethyl-1H-indole-2-carboxylic acidRattus norvegicus (Norway rat)Potency10.000020
3-benzamido-5-bromo-2-benzofurancarboxylic acid methyl esterRattus norvegicus (Norway rat)Potency12.589310
5-bromo-3-[[2-(4-methyl-1-piperazinyl)-1-oxoethyl]amino]-2-benzofurancarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency22.387210
7-[[2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-oxoethyl]amino]-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency28.183810
2-(4-chlorophenyl)-3-(2-furanylmethyl)imidazo[4,5-b]quinoxalineRattus norvegicus (Norway rat)Potency0.316210
1-[(4-methylphenyl)methyl]-4-[4-(4-methylphenyl)-1-piperazinyl]pyrazolo[3,4-d]pyrimidineRattus norvegicus (Norway rat)Potency28.183810
6-[(2,4-dichlorophenoxy)methyl]-3-(2-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoleRattus norvegicus (Norway rat)Potency3.981110
2-cyano-2-[3-(4-morpholinyl)-2-quinoxalinyl]acetic acid hexyl esterRattus norvegicus (Norway rat)Potency2.818410
6-tert-butyl-3-cyclohexyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazineRattus norvegicus (Norway rat)Potency22.387210
4-[4-(1H-benzimidazol-2-ylmethyl)-1-piperazinyl]benzofuro[3,2-d]pyrimidineRattus norvegicus (Norway rat)Potency31.622810
8-(1,3-benzothiazol-2-ylthio)-3-methyl-7-pentylpurine-2,6-dioneRattus norvegicus (Norway rat)Potency12.589310
LSM-32400Rattus norvegicus (Norway rat)Potency28.183810
N-[3-(2-phenylethyl)-2,4-dihydro-1H-1,3,5-triazin-6-yl]-1,3-benzoxazol-2-amineRattus norvegicus (Norway rat)Potency25.118910
2-(4-benzofuro[3,2-d]pyrimidinylthio)-1-thiophen-2-ylethanoneRattus norvegicus (Norway rat)Potency16.271020
(4-chloro-5-hydroxy-3-benzofuranyl)-phenylmethanoneRattus norvegicus (Norway rat)Potency11.220210
1-(thiophen-2-ylmethyl)-3-thiophen-2-ylsulfonyl-2-pyrrolo[3,2-b]quinoxalinamineRattus norvegicus (Norway rat)Potency31.622810
5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-(1-naphthalenylmethyl)-4-oxazolecarbonitrileRattus norvegicus (Norway rat)Potency0.354810
N-(4-fluorophenyl)-2-[(2-methyl-4-benzofuro[3,2-d]pyrimidinyl)thio]acetamideRattus norvegicus (Norway rat)Potency26.651420
3-[[2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-oxoethyl]amino]-1H-indole-2-carboxylic acid methyl esterRattus norvegicus (Norway rat)Potency2.238710
3-[[2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-1-oxoethyl]amino]-5-ethoxy-1H-indole-2-carboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency7.079510
N-(4-chlorophenyl)-2-[3-(2-furanylmethyl)-4-imino-6,6-dimethyl-2-oxo-5,8-dihydropyrano[2,3]thieno[2,4-b]pyrimidin-1-yl]acetamideRattus norvegicus (Norway rat)Potency7.943310
2-[3-(2-furanylmethyl)-4-imino-6,6-dimethyl-2-oxo-5,8-dihydropyrano[2,3]thieno[2,4-b]pyrimidin-1-yl]-N-phenylacetamideRattus norvegicus (Norway rat)Potency15.848910
3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-ethylpropanamideRattus norvegicus (Norway rat)Potency25.118910
7-(3,4-dimethoxyphenyl)-4-methyl-2-[4-(phenylmethyl)-1-piperazinyl]-7,8-dihydro-6H-quinazolin-5-oneRattus norvegicus (Norway rat)Potency0.025110
5-(3-methoxyphenyl)-N-(2-oxolanylmethyl)-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxamideRattus norvegicus (Norway rat)Potency5.011910
2-amino-6-[3-(1-imidazolyl)propyl]-4-(2-methoxyphenyl)-7-methyl-5-oxo-4H-pyrano[3,2-c]pyridine-3-carbonitrileRattus norvegicus (Norway rat)Potency12.589310
5-(3,5-dimethoxyphenyl)-3-(2-methoxyphenyl)-1,2,4-oxadiazoleRattus norvegicus (Norway rat)Potency28.183810
2-amino-4-(3-chlorophenyl)-6-(2-furanylmethyl)-7-methyl-5-oxo-4H-pyrano[3,2-c]pyridine-3-carboxylic acid methyl esterRattus norvegicus (Norway rat)Potency5.011910
2-methoxy-6-[[(1-propyl-5-benzimidazolyl)amino]methyl]phenolRattus norvegicus (Norway rat)Potency19.952610
5-(1,3-benzodioxol-5-ylmethylamino)-2-(4-morpholinyl)benzoic acid methyl esterRattus norvegicus (Norway rat)Potency31.622810
4-[(4-ethyl-1-piperazinyl)methyl]-5,7-dimethyl-1-benzopyran-2-oneRattus norvegicus (Norway rat)Potency28.183810
doxepin hydrochlorideRattus norvegicus (Norway rat)Potency8.912510
ag-213Rattus norvegicus (Norway rat)Potency5.298120
bemesetronRattus norvegicus (Norway rat)Potency7.063520
N-(1,3-dioxo-2-phenyl-5-isoindolyl)-2-thiophenecarboxamideRattus norvegicus (Norway rat)Potency12.589310
2-[(2-ethoxy-2-oxoethyl)thio]-1-benzimidazolecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency0.010010
7,8,3'-trihydroxyflavoneRattus norvegicus (Norway rat)Potency25.118910
4-[4-(2-quinoxalinyl)phenoxy]benzene-1,2-dicarbonitrileRattus norvegicus (Norway rat)Potency2.818410
5-(1,3-benzodioxol-5-yl)-2-[(2-chloro-6-fluorophenyl)methyl]tetrazoleRattus norvegicus (Norway rat)Potency35.481310
4-bromotetramisole, (s)-isomerRattus norvegicus (Norway rat)Potency0.501210
(S)-(-)-pindololRattus norvegicus (Norway rat)Potency10.000010
6-methoxy-2-(4-methoxyphenyl)-1-benzopyran-4-oneRattus norvegicus (Norway rat)Potency12.672810
5-(4-methoxyphenyl)-1,2-dihydro-1,2,4-triazole-3-thioneRattus norvegicus (Norway rat)Potency3.981110
N-[(2-phenylethylamino)-sulfanylidenemethyl]benzamideRattus norvegicus (Norway rat)Potency11.220210
2-[(3-cyano-6-cyclopropyl-4-thiophen-2-yl-2-pyridinyl)thio]acetamideRattus norvegicus (Norway rat)Potency12.589310
5-(5-chloro-2-methoxyphenyl)-3H-1,3,4-oxadiazole-2-thioneRattus norvegicus (Norway rat)Potency9.449420
4-chloro-1-methyl-3-nitro-2-quinolinoneRattus norvegicus (Norway rat)Potency11.220210
3,5,5-trimethyl-2-sulfanylidene-1,6-dihydrobenzo[h]quinazolin-4-oneRattus norvegicus (Norway rat)Potency1.412510
3-methyl-N-[4-(4-oxo-3,1-benzoxazin-2-yl)phenyl]butanamideRattus norvegicus (Norway rat)Potency31.622810
N-(4-hydroxy-2-methyl-5-propan-2-ylphenyl)-4-methoxybenzenesulfonamideRattus norvegicus (Norway rat)Potency19.952610
1-[2-(dimethylamino)ethyl]-5-methoxy-N-methyl-2-indolecarboxamideRattus norvegicus (Norway rat)Potency0.158510
N-cyclopentyl-2-[[1-(2-methoxyphenyl)-5-tetrazolyl]thio]acetamideRattus norvegicus (Norway rat)Potency5.011910
2-[(dimethylamino)methyl]-4-methyl-6-(1-methylcyclohexyl)phenolRattus norvegicus (Norway rat)Potency0.707910
dexchlorpheniramineRattus norvegicus (Norway rat)Potency0.010010
7-methoxy-3,5-dimethyl-2-thiazolo[4,5-d]pyrimidinethioneRattus norvegicus (Norway rat)Potency22.387210
bemethylRattus norvegicus (Norway rat)Potency10.000010
4-Acetyl-3-methyl-5-(methylthio)thiophene-2-carboxylic acidRattus norvegicus (Norway rat)Potency1.000010
5-phenyl-1,7-dihydrotetrazolo[1,5-a]pyrimidineRattus norvegicus (Norway rat)Potency3.162310
(4-Methyl-2-oxochromen-7-yl) furan-2-carboxylateRattus norvegicus (Norway rat)Potency15.848910
4-(3,5-dimethyl-1-pyrazolyl)-6-methyl-1-phenylpyrazolo[3,4-d]pyrimidineRattus norvegicus (Norway rat)Potency12.589310
N-(5-acetyl-4-methyl-2-thiazolyl)-2-methylpropanamideRattus norvegicus (Norway rat)Potency11.904820
5-phenyl-1,3,4-oxadiazole-2-thiolRattus norvegicus (Norway rat)Potency11.904820
N-[6-methyl-2-(4-methylphenyl)-5-benzotriazolyl]-3-pyridinecarboxamideRattus norvegicus (Norway rat)Potency21.421520
N-[[(6-methyl-1,3-benzothiazol-2-yl)amino]-sulfanylidenemethyl]-2-thiophenecarboxamideRattus norvegicus (Norway rat)Potency3.548110
8-(2,5-dimethylphenoxy)-1,3-dimethyl-7-prop-2-enylpurine-2,6-dioneRattus norvegicus (Norway rat)Potency3.548110
2-amino-4-(4-chlorophenyl)-6-methyl-3-pyridinecarbonitrileRattus norvegicus (Norway rat)Potency25.118910
2-(2,4-dimethylanilino)-4-(methoxymethyl)-6-methyl-3-pyridinecarbonitrileRattus norvegicus (Norway rat)Potency28.183810
3-[(4,8-dimethyl-2-quinolinyl)thio]propanoic acidRattus norvegicus (Norway rat)Potency11.294720
(5-hydroxy-2-phenyl-3-benzofuranyl)-(4-morpholinyl)methanoneRattus norvegicus (Norway rat)Potency31.622810
2-amino-5-ethyl-4-(2-furanyl)-6-propyl-3-pyridinecarbonitrileRattus norvegicus (Norway rat)Potency22.387210
N-cyclopentyl-2-benzo[e]benzofurancarboxamideRattus norvegicus (Norway rat)Potency35.481310
2-[(2-fluorophenyl)methylthio]-5-(4-methylphenyl)-1,3,4-oxadiazoleRattus norvegicus (Norway rat)Potency11.220210
4-(benzenesulfonyl)-5-(ethylthio)-2-phenyloxazoleRattus norvegicus (Norway rat)Potency11.220210
6-methoxy-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazineRattus norvegicus (Norway rat)Potency1.000010
1-(3-pyridinylmethyl)-3-[2-(trifluoromethyl)-1,3-benzodioxol-2-yl]ureaRattus norvegicus (Norway rat)Potency0.158510
3-(4-bromophenyl)-6-phenyl-1,4-dihydro-1,3,5-triazine-2-thioneRattus norvegicus (Norway rat)Potency1.122010
6-methyl-4-(trifluoromethyl)-7,8,9,10-tetrahydropyrano[2,3-f]quinolin-2-oneRattus norvegicus (Norway rat)Potency15.848910
N-[7-(1-oxopropyl)-2,3-dihydro-1,4-benzodioxin-6-yl]benzamideRattus norvegicus (Norway rat)Potency28.183810
1-(3-nitrophenyl)-3-phenyl-2-propyn-1-oneRattus norvegicus (Norway rat)Potency31.622810
6-bromo-3-phenyl-2-sulfanylidene-1H-quinazolin-4-oneRattus norvegicus (Norway rat)Potency28.183810
4-amino-N-(4-ethoxyphenyl)benzenesulfonamideRattus norvegicus (Norway rat)Potency14.125410
1-[[3-(4-chlorophenoxy)phenyl]methyl]-4-ethylpiperazineRattus norvegicus (Norway rat)Potency14.125410
N4,N4-dimethyl-N1-(4-nitro-1,1-dioxo-2,5-dihydrothiophen-3-yl)benzene-1,4-diamineRattus norvegicus (Norway rat)Potency10.000010
1-(4-ethylphenyl)-N-(3-pyridinylmethyl)methanamineRattus norvegicus (Norway rat)Potency1.000010
4-chloro-1-ethyl-3-nitro-2-quinolinoneRattus norvegicus (Norway rat)Potency11.220210
4-methyl-N-(3-nitrophenyl)-5-phenyl-3-thiophenecarboxamideRattus norvegicus (Norway rat)Potency28.183810
4,5-dimethoxy-2-[(1-oxo-2-thiophen-2-ylethyl)amino]benzoic acid methyl esterRattus norvegicus (Norway rat)Potency5.011910
LSM-20909Rattus norvegicus (Norway rat)Potency3.162310
acetic acid [4-[(4-hydroxyanilino)-oxomethyl]-2-methoxyphenyl] esterRattus norvegicus (Norway rat)Potency4.466810
6-(1,4,5,7-tetramethyl-6-pyrrolo[3,4-d]pyridazinyl)quinolineRattus norvegicus (Norway rat)Potency10.000010
8-methyl-1,5-dihydropyrimido[5,4-b]indole-4-thioneRattus norvegicus (Norway rat)Potency12.589320
7,8-dimethoxy-1,5-dimethyl-3-phenylpyrazolo[3,4-c]isoquinolineRattus norvegicus (Norway rat)Potency11.220210
(2'-(4-aminophenyl)-(2,5'-bi-1h-benzimidazol)-5-amine)Rattus norvegicus (Norway rat)Potency11.294720
2-methyl-3,7-diphenylpyrazolo[1,5-a]pyrimidineRattus norvegicus (Norway rat)Potency11.220210
N-[5-(methylthio)-1,3,4-thiadiazol-2-yl]-3-phenylpropanamideRattus norvegicus (Norway rat)Potency28.183810
2-phenyl-1H-quinazoline-4-thioneRattus norvegicus (Norway rat)Potency12.589310
2-methoxy-4-(methylthio)-N-pyridin-4-ylbenzamideRattus norvegicus (Norway rat)Potency14.125410
3-[[(4-methoxyphenyl)-oxomethyl]amino]-2-thiophenecarboxylic acid methyl esterRattus norvegicus (Norway rat)Potency15.848910
4-chloro-N-[2-fluoro-5-(trifluoromethyl)phenyl]-2-methyl-3-pyrazolecarboxamideRattus norvegicus (Norway rat)Potency11.319220
4,5-dimethylcyclopenta[c]quinolizine-1,2-dicarboxylic acid dimethyl esterRattus norvegicus (Norway rat)Potency10.000010
4-chloro-3-ethoxy-N-(4-ethylphenyl)benzenesulfonamideRattus norvegicus (Norway rat)Potency25.118910
5-methyl-1-phenyl-4-pyrazolecarboxylic acid (4-methoxyphenyl) esterRattus norvegicus (Norway rat)Potency12.589310
2-methoxy-3-methyl-N-[4-(4-morpholinylmethyl)phenyl]benzamideRattus norvegicus (Norway rat)Potency2.818410
N-(6-bromo-2,3-dihydro-1,4-benzodioxin-7-yl)-2-furancarboxamideRattus norvegicus (Norway rat)Potency0.251210
5-methyl-N-(5-methyl-3-isoxazolyl)-3-isoxazolecarboxamideRattus norvegicus (Norway rat)Potency12.589310
1,4,8-trimethyl-12-quinolino[2,3-b]quinolinamineRattus norvegicus (Norway rat)Potency10.000010
4-methoxy-2-[3-(4-methoxyphenyl)-5-methyl-1H-pyrazol-4-yl]phenolRattus norvegicus (Norway rat)Potency28.183810
N,N-diethyl-4-[oxo-(2,4,6-trimethylphenyl)methyl]benzamideRattus norvegicus (Norway rat)Potency12.589310
3-methyl-6-(1-pyrrolidinyl)-[1,2,4]triazolo[4,3-b]pyridazineRattus norvegicus (Norway rat)Potency10.000010
N-[[(6-methyl-4-pyrimidinyl)thio]methyl]benzamideRattus norvegicus (Norway rat)Potency1.995310
1-(3,4-dimethoxyphenyl)-1-cyclohexanecarboxamideRattus norvegicus (Norway rat)Potency31.622810
5-(1-methyl-2-benzimidazolyl)-2-thiophenecarboxaldehydeRattus norvegicus (Norway rat)Potency1.258910
4-(4-morpholinylmethyl)-3-quinolinolRattus norvegicus (Norway rat)Potency25.118910
2-amino-9-ethyl-3-pyrido[2,3-b]indolecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency28.183810
4-sulfanylidene-1,6,7,8,9,10-hexahydropyrimido[3,4]pyrrolo[3,5-a]azepine-11-carbonitrileRattus norvegicus (Norway rat)Potency14.125410
5-(4-chlorophenyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-furancarboxamideRattus norvegicus (Norway rat)Potency28.183810
1-(5-ethyl-2,4-dihydroxyphenyl)-2-(2-fluorophenoxy)ethanoneRattus norvegicus (Norway rat)Potency10.000010
N-(5-fluoro-2-methylphenyl)-1,3-benzodioxole-5-carboxamideRattus norvegicus (Norway rat)Potency19.952610
N-[(2-methoxyphenyl)methyl]-4-(1-piperidinyl)anilineRattus norvegicus (Norway rat)Potency3.548110
5-(4-morpholinyl)-2-thiophen-2-yl-4-oxazolecarbonitrileRattus norvegicus (Norway rat)Potency11.220210
4-[methyl(methylsulfonyl)amino]-N-(2-phenylethyl)benzamideRattus norvegicus (Norway rat)Potency22.387210
N-(3,4-dimethyl-2-thiazolylidene)benzamideRattus norvegicus (Norway rat)Potency0.251210
1-(cycloheptylideneamino)-3-(4-fluorophenyl)thioureaRattus norvegicus (Norway rat)Potency0.020010
(3-amino-1,2,4-triazol-4-yl)-(2,5-dimethylphenyl)methanoneRattus norvegicus (Norway rat)Potency1.258910
N2-(4-fluorophenyl)-6-(3-methyl-2-benzofuranyl)-1,3,5-triazine-2,4-diamineRattus norvegicus (Norway rat)Potency10.000010
1-(4-methylphenyl)sulfonyl-4-phenyl-3-pyrazolamineRattus norvegicus (Norway rat)Potency31.622810
1-(4-methyl-1-piperidinyl)-2-[(3-methyl-2-quinoxalinyl)thio]ethanoneRattus norvegicus (Norway rat)Potency12.589320
2-(4-ethoxyanilino)-3-methoxynaphthalene-1,4-dioneRattus norvegicus (Norway rat)Potency12.589310
3-[(2-chloro-6-fluorophenyl)methylthio]-4-ethyl-5-(2-furanyl)-1,2,4-triazoleRattus norvegicus (Norway rat)Potency3.162310
2-thiophenecarboxylic acid (6-methyl-2-oxo-1H-quinolin-3-yl)methyl esterRattus norvegicus (Norway rat)Potency28.183810
6-methoxy-3-[(3-methylanilino)methyl]-1H-quinolin-2-oneRattus norvegicus (Norway rat)Potency1.584910
2-[[3-(5-methyl-2-furanyl)-1-oxopropyl]amino]benzene-1,4-dicarboxylic acid dimethyl esterRattus norvegicus (Norway rat)Potency7.943310
3-phenyl-5-(2-phenylphenyl)-1,2,4-oxadiazoleRattus norvegicus (Norway rat)Potency14.125410
5-(3,4-diethoxyphenyl)-3-pyridin-4-yl-1,2,4-oxadiazoleRattus norvegicus (Norway rat)Potency35.481310
2-methoxy-5-propan-2-yl-N-(2-pyridinyl)benzenesulfonamideRattus norvegicus (Norway rat)Potency11.220210
1-phenyl-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)ethanoneRattus norvegicus (Norway rat)Potency14.125410
2,4-dimethyl-N-[4-(1-pyrrolidinyl)phenyl]benzamideRattus norvegicus (Norway rat)Potency12.589310
3-tert-butyl-7-[[2-(4-methylphenyl)-2-oxoethyl]thio]-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-oneRattus norvegicus (Norway rat)Potency28.183810
3-tert-butyl-7-[[2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]thio]-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-oneRattus norvegicus (Norway rat)Potency28.183810
N-[(3-bromo-4-ethoxy-5-methoxyphenyl)methyl]-2,3-dihydro-1,4-benzodioxin-6-amineRattus norvegicus (Norway rat)Potency7.079510
2-[(3,5-dimethyl-4-isoxazolyl)methylthio]-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-oneRattus norvegicus (Norway rat)Potency31.622810
N-[4-(1,3-benzothiazol-2-yl)phenyl]-2-[(4-tert-butylphenyl)sulfonylamino]acetamideRattus norvegicus (Norway rat)Potency15.848910
5-[(5-methoxycarbonyl-2-methyl-3-furanyl)methoxy]-2-methyl-3-benzofurancarboxylic acid methyl esterRattus norvegicus (Norway rat)Potency11.294720
5-chloro-N-(2-furanylmethyl)-2-[[(4-methoxyphenyl)-oxomethyl]amino]benzamideRattus norvegicus (Norway rat)Potency29.903320
3-[(4-nitrophenyl)methoxy]-7,8,9,10-tetrahydrobenzo[c][1]benzopyran-6-oneRattus norvegicus (Norway rat)Potency31.622810
1-[[[2-(difluoromethoxy)phenyl]-oxomethyl]amino]-3-(4-fluorophenyl)thioureaRattus norvegicus (Norway rat)Potency28.183810
2-[(3-cyano-4-phenyl-6-thiophen-2-yl-2-pyridinyl)thio]-N-propan-2-ylacetamideRattus norvegicus (Norway rat)Potency18.854120
5-[(2,4-dichlorophenoxy)methyl]-N-(2-fluorophenyl)-2-furancarboxamideRattus norvegicus (Norway rat)Potency1.000010
2-[(3-cyano-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio]-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)acetamideRattus norvegicus (Norway rat)Potency25.118910
3-amino-N-(2-fluorophenyl)-6-(phenylmethyl)-4-(trifluoromethyl)-2-thieno[2,3-b]pyridinecarboxamideRattus norvegicus (Norway rat)Potency20.811420
5-(4-bromophenyl)-N-(2-methoxyphenyl)-2-furancarboxamideRattus norvegicus (Norway rat)Potency19.952610
5-bromo-N-[[4-[(3,5-dimethylphenyl)sulfamoyl]anilino]-sulfanylidenemethyl]-2-furancarboxamideRattus norvegicus (Norway rat)Potency10.000010
N-[[methyl-(phenylmethyl)amino]-sulfanylidenemethyl]-4-phenylbenzamideRattus norvegicus (Norway rat)Potency10.000010
2-chloro-N-[3-(5-methyl-1,3-benzoxazol-2-yl)phenyl]-5-(1,2,4-triazol-4-yl)benzamideRattus norvegicus (Norway rat)Potency23.753120
N-[4,6-bis(4-morpholinyl)-1,3,5-triazin-2-yl]-2-(methylthio)-1,3-benzothiazol-6-amineRattus norvegicus (Norway rat)Potency31.622810
4-[[4-bromo-5-(4-morpholinyl)-2-furanyl]methylideneamino]phenolRattus norvegicus (Norway rat)Potency10.000010
N-[3-[oxo-(3-pyridinylmethylamino)methyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-2-furancarboxamideRattus norvegicus (Norway rat)Potency12.589310
2-amino-4-(4-chlorophenyl)-1-(4-methylphenyl)-6-oxopyridine-3,5-dicarbonitrileRattus norvegicus (Norway rat)Potency29.903320
5-ethyl-2-[[oxo-(3,4,5-trimethoxyphenyl)methyl]amino]-3-thiophenecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency1.995310
2-[[3-cyano-6-(4-methylphenyl)-4-(trifluoromethyl)-2-pyridinyl]thio]-N-(4-methoxyphenyl)acetamideRattus norvegicus (Norway rat)Potency25.118910
rhi002Rattus norvegicus (Norway rat)Potency28.183810
[5-phenyl-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-(1-piperidinyl)methanoneRattus norvegicus (Norway rat)Potency7.600620
2-[[2-(5-methyl-2-thiophenyl)-2-oxoethyl]thio]-3-phenyl-4-quinazolinoneRattus norvegicus (Norway rat)Potency28.183810
N-(2-methoxyphenyl)-5-methyl-3-[(2-methylphenyl)methyl]-4-oxo-6-thieno[2,3-d]pyrimidinecarboxamideRattus norvegicus (Norway rat)Potency22.387210
N-[2-(3-pyridinyl)-3H-benzimidazol-5-yl]-2-furancarboxamideRattus norvegicus (Norway rat)Potency17.782810
N-[2-(3-chlorophenyl)ethyl]-2-[[3-cyano-6-(3-methoxyphenyl)-2-pyridinyl]thio]acetamideRattus norvegicus (Norway rat)Potency11.220210
2-[[3-cyano-6-(2-furanyl)-4-(trifluoromethyl)-2-pyridinyl]thio]-N,N-diethylacetamideRattus norvegicus (Norway rat)Potency2.511910
4-(4-methoxycarbonylphenyl)-1,2,6-trimethyl-4H-pyridine-3,5-dicarboxylic acid dimethyl esterRattus norvegicus (Norway rat)Potency0.794310
N-[5-(1,3-benzothiazol-2-yl)-2-chlorophenyl]-1,3-benzodioxole-5-carboxamideRattus norvegicus (Norway rat)Potency28.183810
N-(1,3-benzothiazol-2-yl)-2-[methyl-(4-methylphenyl)sulfonylamino]acetamideRattus norvegicus (Norway rat)Potency24.035320
[4-(2-methoxyphenyl)-1-piperazinyl]-[5-(4-methylphenyl)-3-isoxazolyl]methanoneRattus norvegicus (Norway rat)Potency10.000010
N-(2-furanylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamideRattus norvegicus (Norway rat)Potency0.125910
2-(3,4-dimethoxyphenyl)-8-methoxy-4,4-dimethyl-5H-isothiazolo[5,4-c]quinoline-1-thioneRattus norvegicus (Norway rat)Potency0.031610
N-(3-methoxyphenyl)-4-(1-oxopropylamino)benzamideRattus norvegicus (Norway rat)Potency22.387210
N-[5-(4-tert-butylphenyl)-1,3,4-thiadiazol-2-yl]-4-methylbenzamideRattus norvegicus (Norway rat)Potency1.932120
3-(2-chloro-6-fluorophenyl)-N-(3-fluoro-4-methylphenyl)-5-methyl-4-isoxazolecarboxamideRattus norvegicus (Norway rat)Potency19.952610
2-[[[1,3-benzodioxol-5-ylmethyl-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]amino]-sulfanylidenemethyl]amino]benzoic acid methyl esterRattus norvegicus (Norway rat)Potency5.623410
N-(phenylmethyl)-2-[[4-(trifluoromethyl)-5,6-dihydrobenzo[h]quinazolin-2-yl]thio]acetamideRattus norvegicus (Norway rat)Potency10.000010
N-[(6-chloro-2-oxo-4-phenyl-1H-quinolin-3-yl)methyl]-4-methylbenzenesulfonamideRattus norvegicus (Norway rat)Potency28.183810
2-[(3-cyano-6-methoxy-2-quinolinyl)thio]-N-(2-methyl-1,3-benzothiazol-5-yl)acetamideRattus norvegicus (Norway rat)Potency28.183810
1-(6-methoxy-2,2,4-trimethyl-1-quinolinyl)-2-[[5-(4-methylphenyl)-1,3,4-oxadiazol-2-yl]thio]ethanoneRattus norvegicus (Norway rat)Potency10.000010
3-[[2-[[6-fluoro-2-(4-fluorophenyl)-4-quinazolinyl]thio]-1-oxoethyl]amino]benzoic acidRattus norvegicus (Norway rat)Potency10.000010
1-(2,3-dihydroindol-1-yl)-2-[[4-methyl-5-[4-(1-pyrrolidinylsulfonyl)phenyl]-1,2,4-triazol-3-yl]thio]ethanoneRattus norvegicus (Norway rat)Potency28.183810
N-(4-acetylphenyl)-2-[[1-(3,5-dimethoxyphenyl)-5-tetrazolyl]thio]acetamideRattus norvegicus (Norway rat)Potency3.548110
3-chloro-4-[2-(3,4-dimethoxyphenyl)ethylamino]-1-(2-phenylethyl)pyrrole-2,5-dioneRattus norvegicus (Norway rat)Potency0.316210
2-(4-chloro-3-methylphenoxy)acetic acid [4-[(4-methylanilino)-oxomethyl]phenyl] esterRattus norvegicus (Norway rat)Potency0.089110
N-(2-phenylethyl)-5-thiophen-2-yl-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamideRattus norvegicus (Norway rat)Potency28.183810
N-[(1,2-dihydroacenaphthylen-5-ylamino)-sulfanylidenemethyl]-2-phenoxyacetamideRattus norvegicus (Norway rat)Potency13.357420
N-(4-chlorophenyl)carbamic acid 2-pyridinylmethyl esterRattus norvegicus (Norway rat)Potency31.622810
4-bromo-N'-(3,4-dihydro-2H-pyrrol-5-yl)benzohydrazideRattus norvegicus (Norway rat)Potency1.122010
4-methyl-3-(4-morpholinylsulfonyl)benzoic acid [3-[[oxo(thiophen-2-yl)methyl]amino]phenyl] esterRattus norvegicus (Norway rat)Potency0.501210
(4-phenyl-1-piperazinyl)-(9H-xanthen-9-yl)methanoneRattus norvegicus (Norway rat)Potency10.000010
3-[(4-bromophenoxy)methyl]-N-(5-methyl-3-isoxazolyl)benzamideRattus norvegicus (Norway rat)Potency11.220210
3-[(2,4-difluorophenoxy)methyl]-4-methoxybenzaldehydeRattus norvegicus (Norway rat)Potency2.818410
2-[(3-cyano-6-methyl-2-pyridinyl)thio]-N-(2-thiazolyl)acetamideRattus norvegicus (Norway rat)Potency12.589310
LSM-27108Rattus norvegicus (Norway rat)Potency1.412510
3,5-dimethoxy-N-[(2-phenylethylamino)-sulfanylidenemethyl]benzamideRattus norvegicus (Norway rat)Potency8.912510
5-bromo-N-[3-chloro-2-(1-pyrrolidinyl)phenyl]-2-furancarboxamideRattus norvegicus (Norway rat)Potency5.712220
3-[oxo-[4-(2-phenylethyl)-1-piperazinyl]methyl]-1-benzopyran-2-oneRattus norvegicus (Norway rat)Potency1.000010
6-bromo-N-[2-(dimethylamino)ethyl]-2-oxo-1-benzopyran-3-carboxamideRattus norvegicus (Norway rat)Potency28.183810
5-bromo-N-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)-2-thiophenecarboxamideRattus norvegicus (Norway rat)Potency10.000010
N-(3-isoxazolyl)-1,3-benzodioxole-5-carboxamideRattus norvegicus (Norway rat)Potency29.903320
5-[[[4-(4-fluorophenyl)-5-(phenylmethyl)-1,2,4-triazol-3-yl]thio]methyl]-3-thiophen-2-yl-1,2,4-oxadiazoleRattus norvegicus (Norway rat)Potency5.011910
N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-thiophenecarboxamideRattus norvegicus (Norway rat)Potency25.118910
N-(5-bromo-6-methyl-2-pyridinyl)-3-(2-oxo-1-benzopyran-3-yl)benzamideRattus norvegicus (Norway rat)Potency3.981110
2-[[4,6-bis(1-piperidinyl)-1,3,5-triazin-2-yl]thio]-1-phenylethanoneRattus norvegicus (Norway rat)Potency12.589310
1-oxo-3-(1-piperidinyl)-5,6,7,8-tetrahydropyrrolo[1,2-a]indole-2-carbonitrileRattus norvegicus (Norway rat)Potency3.981110
4-(5-methyl-2-furanyl)-2-[[2-(4-morpholinyl)-1-oxoethyl]amino]-3-thiophenecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency1.412510
2-[(3,5-dimethyl-4-isoxazolyl)methylthio]-3-prop-2-enyl-6,7,8,9-tetrahydro-5H-cyclohepta[2,3]thieno[2,4-b]pyrimidin-4-oneRattus norvegicus (Norway rat)Potency11.220210
N-(2,4-dimethoxyphenyl)-2-(1-pyrrolidinyl)-4-quinazolinamineRattus norvegicus (Norway rat)Potency10.000010
1-(1,2,3-benzothiadiazol-5-yl)-3-(1-naphthalenyl)ureaRattus norvegicus (Norway rat)Potency6.309610
2-[[2-[[1-(2,4-dimethylphenyl)-5-tetrazolyl]thio]-1-oxoethyl]amino]benzoic acid methyl esterRattus norvegicus (Norway rat)Potency10.000010
2-[[5-[(2-methyl-8-quinolinyl)oxymethyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]acetamideRattus norvegicus (Norway rat)Potency10.000010
2-[4-chloro-5-(cyclopentylsulfamoyl)-2-methylphenoxy]-N-cyclohexylacetamideRattus norvegicus (Norway rat)Potency1.122010
2-[[4-(4-methoxyphenyl)-5-(2-phenylethyl)-1,2,4-triazol-3-yl]thio]-N-(phenylmethyl)acetamideRattus norvegicus (Norway rat)Potency31.622810
N-(4-fluorophenyl)-3-([1,2,4]triazolo[4,3-a]quinolin-1-ylthio)propanamideRattus norvegicus (Norway rat)Potency21.421520
4-methoxy-N-[4-[[(1-oxopropylamino)-sulfanylidenemethyl]amino]phenyl]benzamideRattus norvegicus (Norway rat)Potency28.183810
2-[[4-(1,3-dioxo-2-isoindolyl)-1-oxobutyl]amino]-N-(2-furanylmethyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamideRattus norvegicus (Norway rat)Potency11.220210
2-methylsulfonyl-4,6-diphenyl-3-thieno[2,3-b]pyridinamineRattus norvegicus (Norway rat)Potency28.183810
2-[[(4-bromo-1-ethyl-3-pyrazolyl)-oxomethyl]amino]-4-phenyl-3-thiophenecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency6.309610
darunavir ethanolateRattus norvegicus (Norway rat)Potency10.000010
LSM-17286Rattus norvegicus (Norway rat)Potency11.220210
3-[[[(1-oxo-2,2-diphenylethyl)amino]-sulfanylidenemethyl]amino]benzoic acidRattus norvegicus (Norway rat)Potency3.981110
N-(2-furanylmethyl)-2-[[oxo-(3,4,5-trimethoxyphenyl)methyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamideRattus norvegicus (Norway rat)Potency8.912510
5-[(cyclohexylamino)-oxomethyl]-4-methyl-2-[(1-oxo-2-thiophen-2-ylethyl)amino]-3-thiophenecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency28.183810
4-(dimethylsulfamoyl)-N-(1-ethyl-2-oxo-6-benzo[cd]indolyl)benzamideRattus norvegicus (Norway rat)Potency15.848910
N-[[3-(2-oxazolo[4,5-b]pyridinyl)anilino]-sulfanylidenemethyl]-2-furancarboxamideRattus norvegicus (Norway rat)Potency17.782810
1-[5-(5-chloro-2-methylphenyl)-2-furanyl]-N-[4-(4-morpholinyl)phenyl]methanimineRattus norvegicus (Norway rat)Potency11.220210
1-(2-fluorophenyl)-3-[5-(2-fluorophenyl)-1,3,4-thiadiazol-2-yl]ureaRattus norvegicus (Norway rat)Potency10.000010
1-(3,4-dimethylphenyl)-2-[[5-[[2-(4-ethoxyanilino)-4-thiazolyl]methyl]-1,3,4-oxadiazol-2-yl]thio]ethanoneRattus norvegicus (Norway rat)Potency8.912510
1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[[2-(phenylmethyl)-4-quinazolinyl]thio]ethanoneRattus norvegicus (Norway rat)Potency28.183810
2-[(2-propyl-4-quinazolinyl)thio]-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamideRattus norvegicus (Norway rat)Potency12.589310
1-(3,4-dihydro-1H-isoquinolin-2-yl)-2-[(2-propyl-4-quinazolinyl)thio]ethanoneRattus norvegicus (Norway rat)Potency22.387210
N-(5-methyl-3-isoxazolyl)-2-[(2-propan-2-yl-4-quinazolinyl)thio]acetamideRattus norvegicus (Norway rat)Potency12.589310
4-cyano-N-methyl-N-[5-(2-pyridinyl)-1,3,4-thiadiazol-2-yl]benzamideRattus norvegicus (Norway rat)Potency28.183810
7-methyl-2-[4-(4-methylphenyl)sulfonyl-1,4-diazepan-1-yl]-3-quinolinecarbonitrileRattus norvegicus (Norway rat)Potency31.622810
4-methyl-2-[(1-oxo-2-phenoxyethyl)amino]-N-phenyl-5-thiazolecarboxamideRattus norvegicus (Norway rat)Potency22.387210
N',2-dimethyl-N'-[3-(trifluoromethyl)-2-quinoxalinyl]benzohydrazideRattus norvegicus (Norway rat)Potency5.623410
7-anilino-3-(4-bromophenyl)-5-(4-morpholinyl)-1,4-thiazepine-6-carbonitrileRattus norvegicus (Norway rat)Potency28.183810
7-(4-methoxyphenyl)-2-(1-pyrrolyl)-[1,2,4]triazolo[1,5-a]pyrimidineRattus norvegicus (Norway rat)Potency12.589310
2-[2-[2-(3-fluorophenyl)-4-thiazolyl]ethyl]isoindole-1,3-dioneRattus norvegicus (Norway rat)Potency12.589310
N-[2,5-dioxo-6-(4-phenoxyphenyl)-3-pyrano[3,2-c]pyridinyl]benzamideRattus norvegicus (Norway rat)Potency28.183810
6-(4-methyl-1-piperazinyl)-2-(3,4,5-trimethoxyphenyl)-1H-benzimidazoleRattus norvegicus (Norway rat)Potency12.589310
2-(4-methylsulfonylphenyl)-6-imidazo[1,2-a]pyridinecarboxylic acid methyl esterRattus norvegicus (Norway rat)Potency11.220210
2-(2,4-dichlorophenyl)-5-[2-(methylthio)phenyl]-1,3,4-oxadiazoleRattus norvegicus (Norway rat)Potency28.183810
(4-chlorophenyl)-[4-[[(2,4-dichlorophenyl)thio]methyl]-4-hydroxy-1-piperidinyl]methanoneRattus norvegicus (Norway rat)Potency22.387210
2-(3,5-dimethyl-4-nitro-1-pyrazolyl)-N-[(2-methyl-4-quinolinyl)methyl]acetamideRattus norvegicus (Norway rat)Potency3.162310
4-[1-[(3-methoxyphenyl)methyl]-2-benzimidazolyl]-1,2,5-oxadiazol-3-amineRattus norvegicus (Norway rat)Potency0.354810
4-methoxy-N-(8-methyl-[1,3]dioxolo[4,5-g]quinazolin-6-yl)benzamideRattus norvegicus (Norway rat)Potency28.934220
7-methyl-4-oxo-2-[(phenylmethyl)amino]-3-pyrido[1,2-a]pyrimidinecarboxaldehydeRattus norvegicus (Norway rat)Potency22.387210
2-[(4-cyano-1-methyl-5,6,7,8-tetrahydroisoquinolin-3-yl)thio]-N-(3-ethoxyphenyl)acetamideRattus norvegicus (Norway rat)Potency3.571720
11-[2-(diethylamino)ethylamino]-7,8,9,10-tetrahydrobenzimidazolo[1,2-b]isoquinoline-6-carbonitrileRattus norvegicus (Norway rat)Potency2.511910
cinnarizineRattus norvegicus (Norway rat)Potency11.220210
capsaicinRattus norvegicus (Norway rat)Potency2.818410
fluoxetineRattus norvegicus (Norway rat)Potency12.589310
N-(2,4-dichlorophenyl)-4-phenylbenzamideRattus norvegicus (Norway rat)Potency28.183810
1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(1,3-benzothiazol-2-ylthio)methyl]-4-triazolecarboxylic acid methyl esterRattus norvegicus (Norway rat)Potency20.895420
2-chloro-4,6-diphenyl-5-pyrimidinamineRattus norvegicus (Norway rat)Potency11.220210
2-[[[(3-methyl-1-oxobutyl)amino]-sulfanylidenemethyl]amino]-N-phenylbenzamideRattus norvegicus (Norway rat)Potency5.011910
2-chloro-4,6-diphenylpyrimidineRattus norvegicus (Norway rat)Potency0.501210
N,N-dibutyl-2-[[2-(1,3-dioxo-2-isoindolyl)-1-oxoethyl]amino]benzamideRattus norvegicus (Norway rat)Potency5.011910
N-[2-methoxy-5-(3-methyl-4-oxo-1-phthalazinyl)phenyl]-2-(4-methylphenoxy)acetamideRattus norvegicus (Norway rat)Potency0.794310
1-[(3,4-dichlorophenyl)methyl]indole-2,3-dioneRattus norvegicus (Norway rat)Potency22.387210
2-(2-furanyl)-3,5-dimethyl-4-oxido-6-phenylpyrazin-1-ium 1-oxideRattus norvegicus (Norway rat)Potency0.031610
2-[(6-amino-3,5-dicyano-4-thiophen-2-yl-2-pyridinyl)thio]-N-[(2-methoxyphenyl)methyl]acetamideRattus norvegicus (Norway rat)Potency3.548110
2-[[4-ethyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]-1-(4-methylphenyl)ethanoneRattus norvegicus (Norway rat)Potency12.589310
4-(4-chlorophenyl)-N-(3-pyridinylmethyl)-6-(trifluoromethyl)-2-pyrimidinamineRattus norvegicus (Norway rat)Potency11.220210
3-amino-N-(2-fluorophenyl)-6-(2-furanyl)-2-thieno[2,3-b]pyridinecarboxamideRattus norvegicus (Norway rat)Potency6.309610
3-cyclohexyl-10-methyl-2-thiophen-2-ylpyrimido[4,5-b]quinoline-4,5-dioneRattus norvegicus (Norway rat)Potency1.995310
LSM-20401Rattus norvegicus (Norway rat)Potency0.031610
N-[4-[(3,4-dimethyl-5-isoxazolyl)sulfamoyl]phenyl]-2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)thio]acetamideRattus norvegicus (Norway rat)Potency0.316210
2-[(2-methyl-4-benzofuro[3,2-d]pyrimidinyl)thio]-N-(phenylmethyl)acetamideRattus norvegicus (Norway rat)Potency28.183810
2-[(2-methyl-4-benzofuro[3,2-d]pyrimidinyl)thio]-N-(2-phenylethyl)acetamideRattus norvegicus (Norway rat)Potency6.309610
3,4,5-trimethoxy-N-(3-methyl-1,3-benzothiazol-2-ylidene)benzamideRattus norvegicus (Norway rat)Potency28.183810
4-amino-2-[(4-amino-6-anilino-1,3,5-triazin-2-yl)methylthio]-5-pyrimidinecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency28.183810
6-(4-bromophenyl)-3-methyl-1-[2-(2H-tetrazol-5-yl)ethyl]-4-(trifluoromethyl)pyrazolo[3,4-b]pyridineRattus norvegicus (Norway rat)Potency1.995310
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-ethyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanoneRattus norvegicus (Norway rat)Potency10.000010
N-(2-methyl-1,3-benzothiazol-6-yl)-2,3-dihydro-1,4-benzodioxin-6-sulfonamideRattus norvegicus (Norway rat)Potency1.258910
2-[7-chloro-2,3-dioxo-4-(phenylmethyl)-1-quinoxalinyl]-N-(3-fluorophenyl)acetamideRattus norvegicus (Norway rat)Potency28.183810
2-(1,3-dimethyl-2-benzimidazolylidene)-4-[(6-ethyl-4-thieno[2,3-d]pyrimidinyl)thio]-3-oxobutanenitrileRattus norvegicus (Norway rat)Potency15.848910
N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-2-quinolinecarboxamideRattus norvegicus (Norway rat)Potency31.622810
3-[[[5-[3-(1-piperidinylsulfonyl)phenyl]-1,3,4-oxadiazol-2-yl]thio]methyl]-1,2,3-benzotriazin-4-oneRattus norvegicus (Norway rat)Potency1.122010
3-(benzenesulfonyl)-N-(3-methylphenyl)-5-triazolo[1,5-a]quinazolinamineRattus norvegicus (Norway rat)Potency31.622810
4-[[oxo-(1-phenyl-3-pyridin-4-yl-4-pyrazolyl)methyl]amino]benzoic acid methyl esterRattus norvegicus (Norway rat)Potency12.589310
N-(4-fluorophenyl)-2-(5-methoxy-1-oxo-2-isoquinolinyl)acetamideRattus norvegicus (Norway rat)Potency21.169920
N-(4-acetylphenyl)-5-[(phenylthio)methyl]-2-furancarboxamideRattus norvegicus (Norway rat)Potency19.118020
4-fluoro-3-methoxy-N-(2-pyridinyl)benzenesulfonamideRattus norvegicus (Norway rat)Potency10.000010
N-(4-methoxyphenyl)-5-(phenoxymethyl)-2-furancarboxamideRattus norvegicus (Norway rat)Potency10.000010
2-[[2-[2-(2,3-dihydroindol-1-yl)-2-oxoethyl]-1-oxo-5-isoquinolinyl]oxy]acetic acid ethyl esterRattus norvegicus (Norway rat)Potency14.125410
3-phenyl-2-sulfanylidene-1H-benzofuro[3,2-d]pyrimidin-4-oneRattus norvegicus (Norway rat)Potency10.750920
2-[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]-oxomethyl]imino-1-(2-methylpropyl)-5-oxo-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency17.782810
2-(4-benzofuro[3,2-d]pyrimidinylthio)-N-(2-ethoxyphenyl)acetamideRattus norvegicus (Norway rat)Potency28.183810
4-[[[5-[(4-chloro-3,5-dimethyl-1-pyrazolyl)methyl]-2-furanyl]-oxomethyl]amino]benzoic acid propan-2-yl esterRattus norvegicus (Norway rat)Potency11.220210
2-methyl-N-(2,3,4,5,6-pentafluorophenyl)-3-furancarboxamideRattus norvegicus (Norway rat)Potency0.707910
5-bromo-N-(2-phenylphenyl)-2-furancarboxamideRattus norvegicus (Norway rat)Potency4.466810
2-[2-(1-naphthalenyloxy)ethylthio]pyrimidineRattus norvegicus (Norway rat)Potency31.622810
2-[2-(4-chlorophenoxy)ethylthio]pyrimidineRattus norvegicus (Norway rat)Potency31.622810
N-[4-(dibutylsulfamoyl)phenyl]-2-thiophen-2-ylacetamideRattus norvegicus (Norway rat)Potency1.258910
2-bromo-N-(9-fluorenylideneamino)benzamideRattus norvegicus (Norway rat)Potency3.162310
2-[(6-amino-3,5-dicyano-4-thiophen-2-yl-2-pyridinyl)thio]acetic acid ethyl esterRattus norvegicus (Norway rat)Potency11.220210
N-(1,3-benzothiazol-2-yl)-2-[[5-(4-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]thio]acetamideRattus norvegicus (Norway rat)Potency0.446710
N-[2-[4-[(4-chlorophenyl)-oxomethyl]-1-piperazinyl]phenyl]-2-benzofurancarboxamideRattus norvegicus (Norway rat)Potency0.794310
1-[5-(2-furanylmethylamino)-3-phenyl-1,2,4-triazol-1-yl]-2-(4-methoxyphenyl)ethanoneRattus norvegicus (Norway rat)Potency1.000010
N-[2-(1-naphthalenyl)-1,3-benzoxazol-5-yl]-1H-1,2,4-triazole-5-carboxamideRattus norvegicus (Norway rat)Potency11.220210
2-[(3-methyl-6-oxo-7,8,9,10-tetrahydrobenzo[c][1]benzopyran-2-yl)oxy]acetic acid ethyl esterRattus norvegicus (Norway rat)Potency1.778310
N-[3-[[2-(2,6-dimethylphenoxy)-1-oxoethyl]amino]phenyl]-2-furancarboxamideRattus norvegicus (Norway rat)Potency0.063110
5-bromo-N-[2-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamideRattus norvegicus (Norway rat)Potency3.162310
2-(2-bromophenoxy)-N-(2-pyridinylmethyl)acetamideRattus norvegicus (Norway rat)Potency12.589310
N-(2-naphthalenyl)-2-[[6-[[[2-(2-naphthalenylamino)-2-oxoethyl]thio]methyl]-2-pyridinyl]methylthio]acetamideRattus norvegicus (Norway rat)Potency1.412510
5-(2-furanyl)-N-[1-[(2-methylphenyl)methyl]-3-pyrazolyl]-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxamideRattus norvegicus (Norway rat)Potency14.125410
5-(2-ethoxyphenyl)-3H-1,3,4-oxadiazole-2-thioneRattus norvegicus (Norway rat)Potency12.589320
N-(2-fluorophenyl)-4-methoxy-2,5-dimethylbenzenesulfonamideRattus norvegicus (Norway rat)Potency0.125910
1-[[4-(2,4,6-trimethylphenyl)-1-piperazinyl]sulfonyl]azepaneRattus norvegicus (Norway rat)Potency31.622810
N-(3-acetylphenyl)-5,7-dimethyl-2-pyrazolo[1,5-a]pyrimidinecarboxamideRattus norvegicus (Norway rat)Potency22.387210
3-(dimethylamino)propyl benzoateRattus norvegicus (Norway rat)Potency15.848910
8-[2-(4-chloro-3,5-dimethylphenoxy)ethoxy]quinolineRattus norvegicus (Norway rat)Potency10.000010
8-[2-(4-chloro-2,5-dimethylphenoxy)ethoxy]quinolineRattus norvegicus (Norway rat)Potency5.011910
4-chloro-N-[(phenacylamino)-sulfanylidenemethyl]benzamideRattus norvegicus (Norway rat)Potency10.000010
N-[(phenacylamino)-sulfanylidenemethyl]cyclohexanecarboxamideRattus norvegicus (Norway rat)Potency22.387210
N-[3-cyano-4,5-bis(4-methoxyphenyl)-2-furanyl]acetamideRattus norvegicus (Norway rat)Potency0.891310
5-bromo-N-(4-methoxy-1,3-benzothiazol-2-yl)-2-thiophenecarboxamideRattus norvegicus (Norway rat)Potency31.622810
1-azepanyl-[2-[4-(difluoromethylthio)anilino]phenyl]methanoneRattus norvegicus (Norway rat)Potency14.125410
4-(difluoromethoxy)-N-[5-[[4-(difluoromethylthio)phenyl]methyl]-2-thiazolyl]benzamideRattus norvegicus (Norway rat)Potency28.183810
1-(2-chlorophenyl)-N-(5-cyclopropyl-1,3,4-thiadiazol-2-yl)-3-methyl-5-thieno[2,3-c]pyrazolecarboxamideRattus norvegicus (Norway rat)Potency10.000010
2-[(4-chlorophenyl)sulfonyl-methylamino]acetic acid (2-anilino-2-oxoethyl) esterRattus norvegicus (Norway rat)Potency3.548110
2,3-dihydro-1,4-benzodioxin-6-carboxylic acid [2-(2,5-dichloroanilino)-2-oxoethyl] esterRattus norvegicus (Norway rat)Potency12.589310
2-[(4-chlorophenyl)methylthio]-5-[3-(1-piperidinylsulfonyl)phenyl]-1,3,4-oxadiazoleRattus norvegicus (Norway rat)Potency12.589310
2-[2-(3,5-dimethyl-1-pyrazolyl)ethyl]-4-thiophen-2-ylthiazoleRattus norvegicus (Norway rat)Potency5.011910
1-(2-methoxyethyl)-7-thiophen-2-yl-5-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4-dioneRattus norvegicus (Norway rat)Potency35.481310
N-(3-chloro-2-quinoxalinyl)-2-naphthalenesulfonamideRattus norvegicus (Norway rat)Potency11.220210
2-[(4-methylphenyl)sulfonylamino]acetic acid [2-(5-bromo-2-thiophenyl)-2-oxoethyl] esterRattus norvegicus (Norway rat)Potency12.924420
2-(2-furanylmethylamino)benzoic acid [2-oxo-2-(3-oxo-2,4-dihydroquinoxalin-1-yl)ethyl] esterRattus norvegicus (Norway rat)Potency1.995310
N2-(5-phenyl-1H-pyrazol-3-yl)benzene-1,2-diamineRattus norvegicus (Norway rat)Potency10.000010
4-[3,4-dihydro-1H-isoquinolin-2-yl(oxo)methyl]-2-methyl-1-phthalazinoneRattus norvegicus (Norway rat)Potency8.912510
N-(4-tert-butyl-2-thiazolyl)-5-methyl-2-thiophenecarboxamideRattus norvegicus (Norway rat)Potency0.794310
4-[2-(4-fluoroanilino)-2-oxoethoxy]-3-methoxy-N-[4-(4-methoxyphenyl)-5-methyl-2-thiazolyl]benzamideRattus norvegicus (Norway rat)Potency28.183810
4-[[5-(1,3-benzothiazol-2-yl)-2-thiophenyl]-oxomethyl]-1-piperazinecarboxaldehydeRattus norvegicus (Norway rat)Potency28.183810
2-[[3-[(4-fluorophenyl)methyl]-4-oxo-2-quinazolinyl]thio]-N-(thiophen-2-ylmethyl)acetamideRattus norvegicus (Norway rat)Potency28.183810
2-[[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethyl]thio]-3-ethyl-5,6-dimethyl-4-thieno[2,3-d]pyrimidinoneRattus norvegicus (Norway rat)Potency35.481310
2-[[5-(5-bromo-2-furanyl)-4-(phenylmethyl)-1,2,4-triazol-3-yl]thio]-1-(2-fluorophenyl)ethanoneRattus norvegicus (Norway rat)Potency8.912510
5-(dimethylsulfamoyl)-N-(diphenylmethyl)-2-(1-pyrrolidinyl)benzamideRattus norvegicus (Norway rat)Potency3.981110
N-cyclohexyl-2-[(4-oxo-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-7-yl)oxy]acetamideRattus norvegicus (Norway rat)Potency28.183810
N-[4-(2-pyridinyl)-2-thiazolyl]cyclopentanecarboxamideRattus norvegicus (Norway rat)Potency15.848910
N-(3-pyridinylmethyl)-1,3-benzodioxol-5-amineRattus norvegicus (Norway rat)Potency31.622810
5-[2-[[2-[[2-furanyl(oxo)methyl]amino]phenyl]-oxomethoxy]-1-oxoethyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency10.000010
N-(4-chloro-2-methoxy-5-methylphenyl)-4-[(3,4-difluorophenyl)sulfonylamino]benzamideRattus norvegicus (Norway rat)Potency5.623410
N-[2-[(1,3-benzodioxol-5-ylmethylamino)-oxomethyl]phenyl]-2-ethoxy-3-pyridinecarboxamideRattus norvegicus (Norway rat)Potency15.065420
5-[[(5,6-dimethyl-4-thieno[2,3-d]pyrimidinyl)thio]methyl]-2-furancarboxylic acid methyl esterRattus norvegicus (Norway rat)Potency28.183810
2-(1,3-benzoxazol-2-ylthio)-1-(2,5-dimethyl-1-prop-2-enyl-3-pyrrolyl)ethanoneRattus norvegicus (Norway rat)Potency14.125410
7-[(4-acetylphenoxy)methyl]-5-thiazolo[3,2-a]pyrimidinoneRattus norvegicus (Norway rat)Potency28.183810
N-[5-chloro-2-(4-methyl-1-piperazinyl)phenyl]-3-(dimethylsulfamoyl)benzamideRattus norvegicus (Norway rat)Potency31.622810
2-[[4-amino-5-[4-(difluoromethoxy)phenyl]-1,2,4-triazol-3-yl]thio]-N-[(2-furanylmethylamino)-oxomethyl]acetamideRattus norvegicus (Norway rat)Potency25.118910
malachite greenRattus norvegicus (Norway rat)Potency11.220210
2-(4-chloro-2-methylphenoxy)-6-(4-fluorophenyl)-3-pyridinecarbonitrileRattus norvegicus (Norway rat)Potency28.183810
2-chloro-N-(7-methyl-9-oxo-2-thioxanthenyl)benzamideRattus norvegicus (Norway rat)Potency10.000010
3-(2,4-dichlorophenyl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazoleRattus norvegicus (Norway rat)Potency0.158510
5-cyano-6-phenoxy-2-phenyl-3-pyridinecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency11.220210
3-chloro-1-(4-methoxyphenyl)-4-(3-methyl-1-piperidinyl)pyrrole-2,5-dioneRattus norvegicus (Norway rat)Potency10.000010
1-(2,6-dimethyl-1-piperidinyl)-2-phenylethanoneRattus norvegicus (Norway rat)Potency12.589310
3-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-phenylpyrrolidine-2,5-dioneRattus norvegicus (Norway rat)Potency12.589310
dihydrosamidineRattus norvegicus (Norway rat)Potency0.199510
1-(5-bicyclo[2.2.1]hept-2-enylmethyl)-4-[3-(trifluoromethyl)phenyl]piperazineRattus norvegicus (Norway rat)Potency3.162310
4-[3-[methyl(2-phenylethyl)amino]butyl]phenolRattus norvegicus (Norway rat)Potency2.238710
2-(difluoromethyl)-4-benzo[h][1]benzopyranoneRattus norvegicus (Norway rat)Potency28.183810
1-anilino-3-[4-(3-anilino-2-hydroxypropoxy)phenoxy]-2-propanolRattus norvegicus (Norway rat)Potency1.000010
4-ethyl-2-methoxy-3-phenyl-3,3a,9,9a-tetrahydropyrrolo[2,3-b]quinoxalineRattus norvegicus (Norway rat)Potency12.589310
6-amino-4-(1,3-benzodioxol-5-yl)-5-cyano-2-methyl-4H-pyran-3-carboxylic acid 2-methoxyethyl esterRattus norvegicus (Norway rat)Potency19.952610
2,4-dichloro-6-[1-(4-morpholinyl)-3-phenylprop-2-ynyl]phenolRattus norvegicus (Norway rat)Potency12.589310
N-(5-bromo-2-pyridinyl)-2,2-dimethyl-3-(2-methylprop-1-enyl)-1-cyclopropanecarboxamideRattus norvegicus (Norway rat)Potency10.000010
LSM-19663Rattus norvegicus (Norway rat)Potency31.622810
1,7,7-trimethyl-4-[(2-methyl-2,3-dihydroindol-1-yl)-oxomethyl]-2-bicyclo[2.2.1]heptanoneRattus norvegicus (Norway rat)Potency0.316210
2-[[(1-butyl-2-benzimidazolyl)amino]methyl]phenolRattus norvegicus (Norway rat)Potency11.220210
2-(2-hydroxyethylamino)-3-(4-methoxyanilino)naphthalene-1,4-dioneRattus norvegicus (Norway rat)Potency11.220210
N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)-2-phenyl-4-quinolinecarboxamideRattus norvegicus (Norway rat)Potency28.183810
2-[1-(3,4-dihydro-2H-quinolin-1-yl)-1-oxopropan-2-yl]isoindole-1,3-dioneRattus norvegicus (Norway rat)Potency1.000010
6-[[(2-methoxycarbonyl-3-thiophenyl)amino]-oxomethyl]-1-cyclohex-3-enecarboxylic acidRattus norvegicus (Norway rat)Potency11.294720
N-(1-adamantyl)-4-[oxo(2-oxolanyl)methyl]-1-piperazinecarboxamideRattus norvegicus (Norway rat)Potency15.848910
2,6-dimethyl-4-thiophen-2-ylsulfonylmorpholineRattus norvegicus (Norway rat)Potency0.089110
2-[(4,7-dimethyl-2-quinazolinyl)thio]-1,2-diphenylethanoneRattus norvegicus (Norway rat)Potency28.183810
1-(2,4-dimethoxyphenyl)-3-[4-(4-morpholinyl)anilino]pyrrolidine-2,5-dioneRattus norvegicus (Norway rat)Potency8.912510
5-(4-methoxyanilino)-2-[(3-methylphenoxy)methyl]-4-oxazolecarbonitrileRattus norvegicus (Norway rat)Potency8.912510
importazoleRattus norvegicus (Norway rat)Potency11.220210
4-(5-(4-methoxyphenyl)-3-phenyl-4,5-dihydro-1h-pyrazol-1-yl)benzenesulfonamideRattus norvegicus (Norway rat)Potency15.848910
3-hydroxy-3-[2-oxo-2-[4-(1-pyrrolyl)phenyl]ethyl]-1H-indol-2-oneRattus norvegicus (Norway rat)Potency28.183810
1-(3,4-dichlorophenyl)sulfonyl-4-[3-[(4-methyl-1,2,4-triazol-3-yl)thio]-4-nitrophenyl]piperazineRattus norvegicus (Norway rat)Potency11.220210
N-[4-[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]phenyl]-2-phenoxybutanamideRattus norvegicus (Norway rat)Potency28.183810
1-[4-(4-morpholinyl)-2,1,3-benzoxadiazol-7-yl]-3-(4-nitrophenyl)ureaRattus norvegicus (Norway rat)Potency7.943310
3-[2-(2,4-dimethyl-3-furanyl)-2-oxoethyl]-3-hydroxy-1-(2-phenylethyl)-2-indoloneRattus norvegicus (Norway rat)Potency2.818410
N-[3-chloro-4-[4-[oxo-(4-propoxyphenyl)methyl]-1-piperazinyl]phenyl]propanamideRattus norvegicus (Norway rat)Potency11.220210
N-[[(5-bromo-6-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-2-(2-chlorophenoxy)acetamideRattus norvegicus (Norway rat)Potency22.387210
2-[2-[5-[(3,4-dimethylanilino)-oxomethyl]-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidin-4-yl]phenoxy]propanoic acid ethyl esterRattus norvegicus (Norway rat)Potency5.011910
4-[[[4-(2-furanylmethyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]benzonitrileRattus norvegicus (Norway rat)Potency11.220210
[4-(benzenesulfonyl)-1-piperazinyl]-[6-bromo-2-(2-pyridinyl)-4-quinolinyl]methanoneRattus norvegicus (Norway rat)Potency11.220210
4-oxido-3-(4-phenoxyphenyl)-4a,5,6,7,8,8a-hexahydroquinoxalin-1-ium 1-oxideRattus norvegicus (Norway rat)Potency31.622810
1-[3-[4-(2-chloro-5-methoxyphenyl)-1-piperazinyl]propyl]-3-(4-methylphenyl)ureaRattus norvegicus (Norway rat)Potency5.623410
N-(2-methoxy-3-dibenzofuranyl)-2-oxolanecarboxamideRattus norvegicus (Norway rat)Potency5.011910
2-[[4-(4-fluorophenyl)-6-(trifluoromethyl)-2-pyrimidinyl]sulfonyl]acetic acid ethyl esterRattus norvegicus (Norway rat)Potency25.787720
2-[(2-furanylmethylthio)methyl]-5-methylimidazo[1,2-a]pyridineRattus norvegicus (Norway rat)Potency3.981110
7-[[[1-(3-methylphenyl)-2-benzimidazolyl]thio]methyl]-5-thiazolo[3,2-a]pyrimidinoneRattus norvegicus (Norway rat)Potency17.782810
1-[(6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl)methoxy]-3-(1-methyl-3,4-dihydro-1H-pyrrolo[1,2-a]pyrazin-2-yl)-2-propanolRattus norvegicus (Norway rat)Potency12.589310
4-(diethylamino)benzoic acid [2-oxo-2-(4-phenyl-1-piperazinyl)ethyl] esterRattus norvegicus (Norway rat)Potency12.589310
4-[[2-(dimethylamino)-2-thiophen-2-ylethyl]amino]-5-methyl-6-thieno[2,3-d]pyrimidinecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency28.183810
5-chloro-N-[2-(2-furanyl)-2-(1-pyrrolidinyl)ethyl]-2-methoxybenzamideRattus norvegicus (Norway rat)Potency15.848910
6-[2-(2-methoxyphenyl)imino-3-(2-oxolanylmethyl)-4-thiazolyl]-4H-1,4-benzoxazin-3-oneRattus norvegicus (Norway rat)Potency11.220210
2-(1,3-diphenyl-4-pyrazolyl)-3-(2-furanylmethyl)-4-thiazolidinoneRattus norvegicus (Norway rat)Potency12.589310
5-[[2,3-dihydro-1,4-benzodioxin-3-yl(oxo)methyl]amino]benzene-1,3-dicarboxylic acid dimethyl esterRattus norvegicus (Norway rat)Potency31.622810
1-thiophen-2-ylsulfonyl-4-piperidinecarboxylic acid 1,3-benzothiazol-2-ylmethyl esterRattus norvegicus (Norway rat)Potency1.258910
7-(3-methoxypropyl)-3-(phenylmethyl)-8-(3-thiophenyl)purine-2,6-dioneRattus norvegicus (Norway rat)Potency28.183810
7-[3-[4-(2-ethoxyphenyl)-1-piperazinyl]-2-hydroxypropoxy]-4-methyl-1-benzopyran-2-oneRattus norvegicus (Norway rat)Potency31.622810
2-amino-4-chlorobenzoic acid [2-oxo-2-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)ethyl] esterRattus norvegicus (Norway rat)Potency28.183810
N-(3-cyanophenyl)-2-(4-ethyl-2,5-dioxo-4-phenyl-1-imidazolidinyl)acetamideRattus norvegicus (Norway rat)Potency31.622810
LSM-1318Rattus norvegicus (Norway rat)Potency3.503610
1,4-dimethoxy-10H-acridine-9-thioneRattus norvegicus (Norway rat)Potency13.534620
u 0126Rattus norvegicus (Norway rat)Potency5.011910
zephiranRattus norvegicus (Norway rat)Potency8.912510
thioperamideRattus norvegicus (Norway rat)Potency0.891310
u-50488Rattus norvegicus (Norway rat)Potency5.611420
amedin hydrochlorideRattus norvegicus (Norway rat)Potency5.773220
2-[[2,2,2-trichloro-1-[(2,2-dimethyl-1-oxopropyl)amino]ethyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid methyl esterRattus norvegicus (Norway rat)Potency5.011910
1-[1-chloro-2-[(2-nitrophenyl)thio]-4-phenyl-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[c]quinolin-8-yl]ethanoneRattus norvegicus (Norway rat)Potency17.488220
1-[5-hydroxy-3-methyl-5-(3-pyridinyl)-4H-pyrazol-1-yl]-2-(4-methylphenyl)ethanoneRattus norvegicus (Norway rat)Potency3.981110
2-[(prop-2-enylthio)-(4,5,6,7-tetrahydro-1H-indol-2-yl)methylidene]propanedinitrileRattus norvegicus (Norway rat)Potency31.622810
N-[3-[(4-chlorophenyl)-oxomethyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-3-pyridinecarboxamideRattus norvegicus (Norway rat)Potency11.220210
7-(2-methoxyphenyl)-5-phenyl-1,7-dihydrotetrazolo[1,5-a]pyrimidineRattus norvegicus (Norway rat)Potency31.622810
yl-109Rattus norvegicus (Norway rat)Potency19.952610
6-amino-5,7,7-tricyano-8-pyridin-4-yl-1,3,8,8a-tetrahydroisoquinoline-2-carboxylic acid (phenylmethyl) esterRattus norvegicus (Norway rat)Potency35.481310
4-(dimethylsulfamoyl)-N-(6,7,8,9-tetrahydro-5H-carbazol-3-ylmethyl)benzamideRattus norvegicus (Norway rat)Potency5.011910
N-cyclopentyl-2-[[2-[5-(4-fluorophenyl)-2-tetrazolyl]-1-oxoethyl]-(2-furanylmethyl)amino]hexanamideRattus norvegicus (Norway rat)Potency6.309610
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-5-methyl-N-(thiophen-2-ylmethyl)-2,1,3-benzothiadiazole-4-sulfonamideRattus norvegicus (Norway rat)Potency11.220210
4-(2-azaspiro[5.5]undecan-2-ylsulfonyl)-N-butan-2-ylbenzenesulfonamideRattus norvegicus (Norway rat)Potency5.623410
1-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[[5-(3,5-dimethylphenyl)-1,3,4-oxadiazol-2-yl]thio]ethanoneRattus norvegicus (Norway rat)Potency17.782810
2-[(3,6-dimethyl-2-quinolinyl)thio]-1-(2-methyl-2,3-dihydroindol-1-yl)ethanoneRattus norvegicus (Norway rat)Potency29.903320
4-ethoxy-N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-[(4-methoxyphenyl)methyl]benzamideRattus norvegicus (Norway rat)Potency14.125410
2-[(3-cyano-8-methyl-2-quinolinyl)thio]-N-(2-oxolanylmethyl)acetamideRattus norvegicus (Norway rat)Potency31.622810
2-[2-methoxyethyl-(1-oxo-2-thiophen-2-ylethyl)amino]-N-[(4-methoxyphenyl)methyl]-2-(4-propan-2-ylphenyl)acetamideRattus norvegicus (Norway rat)Potency12.589310
2-[[2-(cyclohexylamino)-2-oxo-1-thiophen-2-ylethyl]-[1-oxo-2-[[oxo(thiophen-2-yl)methyl]amino]ethyl]amino]acetic acid ethyl esterRattus norvegicus (Norway rat)Potency1.000010
N-[2-[[2-(cyclohexylamino)-2-oxo-1-thiophen-2-ylethyl]-(2-methoxyethyl)amino]-2-oxoethyl]-2-furancarboxamideRattus norvegicus (Norway rat)Potency0.079410
1-[9-[(4-fluorophenyl)methyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-(2-phenylphenyl)ureaRattus norvegicus (Norway rat)Potency1.778310
4-amino-3-[(cyclohexylamino)-oxomethyl]-5-isothiazolecarboxylic acid [1-(cyclohexylamino)-1-oxopropan-2-yl] esterRattus norvegicus (Norway rat)Potency11.464220
N,N-dimethyl-4-[[3-[3-(5-methyl-2-furanyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]sulfonyl]benzenesulfonamideRattus norvegicus (Norway rat)Potency12.589310
1-(2-methyl-2,3-dihydroindol-1-yl)-2-[4-[5-(trifluoromethyl)-1-benzotriazolyl]-1-piperidinyl]ethanoneRattus norvegicus (Norway rat)Potency10.000010
1-(1-tert-butyl-5-tetrazolyl)-N-(phenylmethyl)-1-(3-pyridinyl)-N-(thiophen-2-ylmethyl)methanamineRattus norvegicus (Norway rat)Potency15.848910
N-(2,4-dimethoxyphenyl)-2-[1-(3,4-dimethylphenyl)-4-oxo-5-pyrazolo[3,4-d]pyrimidinyl]acetamideRattus norvegicus (Norway rat)Potency31.622810
N-(1,3-benzodioxol-5-yl)-2-(5-methyl-2-furanyl)-3-imidazo[1,2-a]pyrimidinamineRattus norvegicus (Norway rat)Potency10.000010
2-[5-[[2-(3-methoxypropylamino)-2-oxoethyl]thio]-3-oxo-2H-imidazo[1,2-c]quinazolin-2-yl]-N-(phenylmethyl)acetamideRattus norvegicus (Norway rat)Potency8.912510
N-(4-methyl-5-oxo-2-[1]benzopyrano[4,3-b]pyridinyl)-4-(1-pyrrolidinylsulfonyl)benzamideRattus norvegicus (Norway rat)Potency29.903320
1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(2-pyridinylthio)methyl]-4-triazolecarboxylic acid propan-2-yl esterRattus norvegicus (Norway rat)Potency0.316210
2-[(6-fluoro-1,3-benzothiazol-2-yl)amino]-4-thiazolecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency3.162310
2-[[4-[(2,6-dimethyl-4-morpholinyl)sulfonyl]phenyl]-oxomethyl]imino-3,4-dimethyl-5-thiazolecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency5.011910
1-[2-(2-methoxyanilino)-2-oxoethyl]-2-benzofuro[3,2-b]pyrrolecarboxylic acid methyl esterRattus norvegicus (Norway rat)Potency1.122010
4-morpholinecarboxylic acid [4-[6-amino-5-cyano-3-(4-methylphenyl)-2,4-dihydropyrano[2,3-c]pyrazol-4-yl]phenyl] esterRattus norvegicus (Norway rat)Potency1.000010
5-(4-bromophenyl)-N,N-diethyl-3-isoxazolecarboxamideRattus norvegicus (Norway rat)Potency6.309610
5-(phenylmethoxymethyl)-7-(1-piperidinylmethyl)-8-quinolinolRattus norvegicus (Norway rat)Potency3.548110
2-(3-methylanilino)-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-oneRattus norvegicus (Norway rat)Potency29.903320
3-chloro-4-ethoxy-N-[3-(2-oxazolo[5,4-b]pyridinyl)phenyl]benzamideRattus norvegicus (Norway rat)Potency31.622810
3,8-dimethyl-4-oxo-7,8,9,10-tetrahydro-6H-thieno[1,2]pyrimido[4,5-a]azepine-2-carboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency3.162310
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propanamideRattus norvegicus (Norway rat)Potency0.562310
3,5-dimethyl-N-(2-phenylethyl)-N-(phenylmethyl)-4-isoxazolesulfonamideRattus norvegicus (Norway rat)Potency3.162310
1-[4-[4-[[1-(4-chlorophenyl)sulfonylcyclopropyl]-oxomethyl]-1-piperazinyl]phenyl]ethanoneRattus norvegicus (Norway rat)Potency4.466810
2-[(5-bromo-2-thiophenyl)sulfonyl-methylamino]-N-(6-methyl-1,3-benzothiazol-2-yl)acetamideRattus norvegicus (Norway rat)Potency10.000010
2-(4-ethoxyphenyl)-5-[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-piperidinyl]-6-pyrazolo[1,5-a]pyrimidinecarboxylic acidRattus norvegicus (Norway rat)Potency1.000010
1-[[4-[(4-fluorophenyl)methyl]-5-thieno[3,2-b]pyrrolyl]-oxomethyl]-N-(2-furanylmethyl)-4-piperidinecarboxamideRattus norvegicus (Norway rat)Potency2.818410
5-(6,7-diethoxy-4-oxo-2-sulfanylidene-1H-quinazolin-3-yl)-N-(2-furanylmethyl)pentanamideRattus norvegicus (Norway rat)Potency12.589310
4-[3-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-imidazo[1,2-a]pyrimidinyl]phenolRattus norvegicus (Norway rat)Potency7.079510
3-(3,4-dimethoxyphenyl)-2-methyl-N-[2-(4-morpholinyl)ethyl]-1-oxo-3,4-dihydroisoquinoline-4-carboxamideRattus norvegicus (Norway rat)Potency3.162310
1-methyl-N-[4-(4-morpholinyl)phenyl]-2-quinolinimineRattus norvegicus (Norway rat)Potency2.511910
N-[2-(2-methyl-1-indolyl)ethyl]benzamideRattus norvegicus (Norway rat)Potency10.000010
N-ethyl-3-[4-morpholinyl(oxo)methyl]-4-oxo-N-phenyl-1H-quinoline-6-sulfonamideRattus norvegicus (Norway rat)Potency5.011910
[5-(3-chlorophenyl)-3-isoxazolyl]-[4-(2-methoxyphenyl)-1-piperazinyl]methanoneRattus norvegicus (Norway rat)Potency0.631010
[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-(7-methoxy-2-furo[2,3-b]quinolinyl)methanoneRattus norvegicus (Norway rat)Potency0.005010
2-[[2-(2-ethyl-1-piperidinyl)-2-oxoethyl]thio]-3-methyl-5H-pyrimido[5,4-b]indol-4-oneRattus norvegicus (Norway rat)Potency10.000010
[2-[(2-chloro-6-fluorophenyl)methylthio]-4,5-dihydroimidazol-1-yl]-(2-furanyl)methanoneRattus norvegicus (Norway rat)Potency5.011910
3-(2-chlorophenyl)-5-methyl-N-[3-(3-methyl-2-imidazo[1,2-a]pyrimidinyl)phenyl]-4-isoxazolecarboxamideRattus norvegicus (Norway rat)Potency11.220210
2-[[3-[2-(3,4-dimethoxyphenyl)ethyl]-4-oxo-2-thieno[3,2-d]pyrimidinyl]thio]-N-(5-methyl-3-isoxazolyl)acetamideRattus norvegicus (Norway rat)Potency6.171120
ml012Rattus norvegicus (Norway rat)Potency1.258910
3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)propanamideRattus norvegicus (Norway rat)Potency7.079510
N-[3-(3,5-dimethyl-1-piperidinyl)propyl]-2-[(1-methyl-2-oxo-4-quinolinyl)oxy]acetamideRattus norvegicus (Norway rat)Potency0.251210
N-[2-[4-(3-chlorophenyl)-1-piperazinyl]ethyl]-[1,2,4]triazolo[4,3-a]quinoxalin-4-amineRattus norvegicus (Norway rat)Potency15.848910
N-[3-(N-ethylanilino)propyl]-2,4-dimethyl-6-oxo-3-pyrancarboxamideRattus norvegicus (Norway rat)Potency3.981110
2-chloro-6-[4-morpholinyl(oxo)methyl]-11-pyrido[2,1-b]quinazolinoneRattus norvegicus (Norway rat)Potency19.952610
5-amino-1-(3,5-dimethylphenyl)-N-(phenylmethyl)-4-triazolecarboxamideRattus norvegicus (Norway rat)Potency8.912510
N-[3-cyano-4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]cyclohexanecarboxamideRattus norvegicus (Norway rat)Potency11.220210
2,5-dimethyl-4-(4-methyl-1-piperidinyl)-6-thieno[2,3-d]pyrimidinecarboxylic acidRattus norvegicus (Norway rat)Potency12.924420
1-[[5-methyl-2-(2-methylphenyl)-4-oxazolyl]methyl]-N-(3-pyridinylmethyl)-4-piperidinecarboxamideRattus norvegicus (Norway rat)Potency10.000010
N4,N5-bis(2-ethoxyphenyl)-1H-imidazole-4,5-dicarboxamideRattus norvegicus (Norway rat)Potency0.050110
7-chloro-5-(4-fluorophenyl)-4-(1-oxopropyl)-3,5-dihydro-1H-1,4-benzodiazepin-2-oneRattus norvegicus (Norway rat)Potency1.258910
2-(1-ethyl-4-oxo-3-furo[3,4]pyrrolo[3,5-c][1,2,4]triazinyl)-N-[4-(2-furanyl)butan-2-yl]propanamideRattus norvegicus (Norway rat)Potency10.000010
N-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-1-methyl-4-oxo-6-(1-pyrrolidinylsulfonyl)-3-quinolinecarboxamideRattus norvegicus (Norway rat)Potency0.050110
1-[2-(4-bromophenyl)-2-oxoethyl]-3-(2-furanylmethyl)-6,7-dimethoxyquinazoline-2,4-dioneRattus norvegicus (Norway rat)Potency12.589310
2-[[3-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]thio]-N-(2-oxolanylmethyl)acetamideRattus norvegicus (Norway rat)Potency25.118910
3-(2-fluorophenyl)-2-(4-fluorophenyl)-5,6,7,7a-tetrahydro-3H-pyrrolo[1,2-c]imidazol-1-oneRattus norvegicus (Norway rat)Potency3.162310
benzatropine methanesulfonateRattus norvegicus (Norway rat)Potency2.238710
N-[(4-chlorophenyl)methyl]-4-(2-furanyl)-6-(trifluoromethyl)-2-pyrimidinamineRattus norvegicus (Norway rat)Potency1.584910
5-amino-2-(3-nitrophenyl)-1-phenyl-2H-pyrrole-3,3,4-tricarbonitrileRattus norvegicus (Norway rat)Potency0.050110
2-(trifluoromethyl)-3-imidazo[1,2-a]pyrimidinecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency0.562310
3-(1-methyl-2-benzimidazolyl)-1-phenyl-2-pyrrolo[3,2-b]quinoxalinamineRattus norvegicus (Norway rat)Potency11.220210
2-phenoxy-N-[5-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,4-oxadiazol-2-yl]acetamideRattus norvegicus (Norway rat)Potency3.548110
sb-224289Rattus norvegicus (Norway rat)Potency19.952610
1,8-dinitro-4,5-dihydroxyanthraquinoneRattus norvegicus (Norway rat)Potency28.183810
N-(6-ethoxy-1,3-benzothiazol-2-yl)-4-methoxy-3-(4-morpholinylsulfonyl)benzamideRattus norvegicus (Norway rat)Potency0.891310
4-amino-2-nitrophenolRattus norvegicus (Norway rat)Potency15.848910
2-[[2-[(2-methoxyphenyl)methylamino]-2-oxoethyl]thio]-3-pyridinecarboxylic acid [2-[(2-methoxyphenyl)methylamino]-2-oxoethyl] esterRattus norvegicus (Norway rat)Potency28.183810
n-pentanoyl-2-benzyltryptamineRattus norvegicus (Norway rat)Potency28.183810
7-methoxy-2-(3-methoxyanilino)-3-quinolinecarbonitrileRattus norvegicus (Norway rat)Potency28.183810
6-bromo-2-(4-methylphenyl)-N-[(1-methyl-4-pyrazolyl)methyl]-4-quinolinecarboxamideRattus norvegicus (Norway rat)Potency10.000010
4-[1-(4-bromophenyl)-2-nitroethyl]-5-methyl-2-phenyl-1H-pyrazol-3-oneRattus norvegicus (Norway rat)Potency1.778310
AngolensinRattus norvegicus (Norway rat)Potency3.981110
N-(2-furanylmethyl)-2-[[5-[(2-methyl-1H-indol-3-yl)methyl]-1,3,4-oxadiazol-2-yl]thio]acetamideRattus norvegicus (Norway rat)Potency0.354810
N-[2-(3,4-dimethoxyphenyl)ethyl]-4-dimethoxyphosphoryl-2-(1-naphthalenyl)-5-oxazolamineRattus norvegicus (Norway rat)Potency10.000010
2-[2-[(5-chloro-2-thiophenyl)-oxomethyl]imino-6-fluoro-1,3-benzothiazol-3-yl]acetic acid methyl esterRattus norvegicus (Norway rat)Potency10.000010
4-[4-dimethoxyphosphoryl-2-(1-naphthalenyl)-5-oxazolyl]morpholineRattus norvegicus (Norway rat)Potency25.118910
2-amino-4-nitrophenolRattus norvegicus (Norway rat)Potency22.387210
3-acetyl-6-bromo-2-methyl-4-quinolinecarboxylic acidRattus norvegicus (Norway rat)Potency6.794620
1-[(2,6-dichlorophenyl)methyl]-5-(4-methylphenyl)-2-oxo-3-pyridinecarbonitrileRattus norvegicus (Norway rat)Potency14.101920
2-thiophen-2-yl-4-quinolinecarboxylic acid (2-oxo-3-oxolanyl) esterRattus norvegicus (Norway rat)Potency7.943310
6,8-dibromo-2-thiophen-2-ylquinolineRattus norvegicus (Norway rat)Potency11.294720
1-phenyl-2-[[4-(trifluoromethyl)phenyl]methylthio]imidazoleRattus norvegicus (Norway rat)Potency28.183810
3-(3,5-dimethylanilino)-5-(2-furanyl)-1-cyclohex-2-enoneRattus norvegicus (Norway rat)Potency1.122010
N-[3-[4-(3-chlorophenyl)-1-piperazinyl]-1,4-dioxo-2-naphthalenyl]-2-thiophenesulfonamideRattus norvegicus (Norway rat)Potency28.183810
3-ethyl-2-sulfanylidene-5-thiophen-2-yl-1H-thieno[2,3-d]pyrimidin-4-oneRattus norvegicus (Norway rat)Potency10.000010
6-cyano-7-nitroquinoxaline-2,3-dioneRattus norvegicus (Norway rat)Potency12.589310
2-(4-chlorophenyl)-5-methyl-4-oxo-2,3-dihydro-1H-thieno[3,4-d]pyrimidine-7-carboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency28.183810
5-chloro-4-[methoxy(phenyl)methyl]-1-methyl-3-phenylpyrazoleRattus norvegicus (Norway rat)Potency0.794310
2-[4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-piperidinyl]-3-nitropyridineRattus norvegicus (Norway rat)Potency0.354810
N-(2,2,4-trimethyl-3H-benzofuran-7-yl)benzenesulfonamideRattus norvegicus (Norway rat)Potency8.912510
2-[[2-(1-adamantyl)-2-oxoethyl]thio]-6-amino-4-(4-chlorophenyl)pyridine-3,5-dicarbonitrileRattus norvegicus (Norway rat)Potency3.548110
2-amino-5-(1-benzotriazolyl)-6-methyl-4-phenyl-4H-pyran-3-carbonitrileRattus norvegicus (Norway rat)Potency35.481310
2-amino-4-(5-bromo-2-thiophenyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrileRattus norvegicus (Norway rat)Potency31.622810
6-amino-4-(1-cyclohex-2-enyl)-3-thiophen-2-yl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrileRattus norvegicus (Norway rat)Potency1.000010
5-tert-butyl-7-(4-ethyl-1-piperazinyl)-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidineRattus norvegicus (Norway rat)Potency3.162310
5,7-dimethyl-3-phenyldiazenyl-1H-pyrazolo[1,5-a]pyrimidin-2-oneRattus norvegicus (Norway rat)Potency10.000010
4-chloro-N-[3-(3-methyl-1-piperidinyl)-1,4-dioxo-2-naphthalenyl]benzenesulfonamideRattus norvegicus (Norway rat)Potency10.000010
6-(5,6-Dihydroxy-4-oxo-2-phenylchromen-7-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acidRattus norvegicus (Norway rat)Potency12.589310
2-(4-phenyl-1-piperazinyl)quinoxalineRattus norvegicus (Norway rat)Potency19.952610
N-(4-phenylmethoxyphenyl)-3-[4-(phenylmethyl)-1-piperazinyl]propanamideRattus norvegicus (Norway rat)Potency10.000010
2-amino-7,7-dimethyl-4-(4-methylphenyl)-5-oxo-6,8-dihydro-4H-1-benzopyran-3-carbothioamideRattus norvegicus (Norway rat)Potency31.622810
1-(phenylmethyl)-4-(phenylmethylthio)pyrazolo[3,4-d]pyrimidineRattus norvegicus (Norway rat)Potency1.000010
N-(3,5-dimethylphenyl)-2-(2-nitroethyl)benzamideRattus norvegicus (Norway rat)Potency3.548110
rose bengal(2-)Rattus norvegicus (Norway rat)Potency15.848910
ro 106-9920Rattus norvegicus (Norway rat)Potency28.183810
3-[[4-(diphenylmethyl)-1-piperazinyl]-oxomethyl]-7,8,9,10-tetrahydro-6H-azepino[2,1-b]quinazolin-12-oneRattus norvegicus (Norway rat)Potency28.183810
3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octaneRattus norvegicus (Norway rat)Potency17.782810
1-(2-fluorophenyl)-3-(N-(phenylmethyl)anilino)thioureaRattus norvegicus (Norway rat)Potency31.622810
4-nitrocaramiphenRattus norvegicus (Norway rat)Potency18.073010
N-[1-[(cyclohexylamino)-oxomethyl]cyclohexyl]-N-(2-furanylmethyl)-2-pyridinecarboxamideRattus norvegicus (Norway rat)Potency8.912510
4-(carbamoylamino)benzoic acid [2-(3-chloro-4-methylanilino)-2-oxo-1-phenylethyl] esterRattus norvegicus (Norway rat)Potency14.125410
4-[[2-[(1,1-dioxo-3-thiolanyl)amino]-2-oxoethyl]thio]-2,5-dimethyl-6-thieno[2,3-d]pyrimidinecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency12.589310
3-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-1,5-dihydropyrimido[5,4-b]indole-2,4-dioneRattus norvegicus (Norway rat)Potency7.943310
2-phenylmelatoninRattus norvegicus (Norway rat)Potency31.622810
4-(1H-benzimidazol-2-ylthio)-1-[4-(4-nitrophenyl)-1-piperazinyl]-1-butanoneRattus norvegicus (Norway rat)Potency31.622810
N-(2,4-dimethylphenyl)-3-methyl-5-(4-morpholinylsulfonyl)-2-benzofurancarboxamideRattus norvegicus (Norway rat)Potency22.387210
N-[3-(1,3-benzothiazol-2-yl)phenyl]-4-oxo-1-benzopyran-2-carboxamideRattus norvegicus (Norway rat)Potency28.183810
3-(2-chlorophenyl)-N-[5-(2,4-dichlorophenyl)-1,3,4-thiadiazol-2-yl]-5-methyl-4-isoxazolecarboxamideRattus norvegicus (Norway rat)Potency12.062720
4-[4-diethoxyphosphoryl-2-(1-naphthalenyl)-5-oxazolyl]morpholineRattus norvegicus (Norway rat)Potency12.589310
[4-(2,3-dimethylphenyl)-1-piperazinyl]-[5-[(4-methoxyphenyl)sulfonylmethyl]-2-furanyl]methanoneRattus norvegicus (Norway rat)Potency10.000010
3-(4-methylphenyl)-N-[3-(4-morpholinylsulfonyl)phenyl]-1-phenyl-4-pyrazolecarboxamideRattus norvegicus (Norway rat)Potency22.387210
N-(1,3-benzodioxol-5-ylmethyl)-6-[6-(4-morpholinyl)-4-oxo-2-sulfanylidene-1H-quinazolin-3-yl]hexanamideRattus norvegicus (Norway rat)Potency28.183810
3,5-bis(4-methoxyphenyl)-1H-imidazole-2-thioneRattus norvegicus (Norway rat)Potency12.589310
N-(2-oxo-1-benzopyran-3-yl)cyclohexanecarboxamideRattus norvegicus (Norway rat)Potency17.782810
N-(3-methyl-6-methylsulfonyl-1,3-benzothiazol-2-ylidene)-2,3-dihydro-1,4-benzodioxin-6-carboxamideRattus norvegicus (Norway rat)Potency12.589310
5-oxo-N-[3-(trifluoromethyl)phenyl]-2,3-dihydrothiazolo[3,2-a]pyrimidine-6-carboxamideRattus norvegicus (Norway rat)Potency25.118910
1-(3-methyl-1-piperidinyl)-2-(2-quinoxalinylthio)ethanoneRattus norvegicus (Norway rat)Potency11.557420
1-(2-methylphenyl)-3-(6,7,8,9-tetrahydro-5H-carbazol-3-ylmethyl)thioureaRattus norvegicus (Norway rat)Potency28.183810
[3,5-bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-[2-(4-propan-2-ylphenyl)-4-quinolinyl]methanoneRattus norvegicus (Norway rat)Potency25.118910
3-[3-[4-(4-methoxyphenyl)-1-piperazinyl]propyl]-2-sulfanylidene-1H-pyrido[2,3-d]pyrimidin-4-oneRattus norvegicus (Norway rat)Potency1.778310
sb 415286Rattus norvegicus (Norway rat)Potency19.952610
6-amino-5-cyano-2-[[(3-cyano-6-methyl-7,8-dihydro-5H-1,6-naphthyridin-2-yl)thio]methyl]-4-(4-fluorophenyl)-4H-pyran-3-carboxylic acid methyl esterRattus norvegicus (Norway rat)Potency0.251210
4-phenyl-1,2,3,4-tetrahydroisoquinolineRattus norvegicus (Norway rat)Potency22.387210
1-[(2,4-dichlorophenyl)methyl]-4-(methylthio)-2-oxo-6-phenyl-3-pyridinecarbonitrileRattus norvegicus (Norway rat)Potency14.125410
1-cyclohexyl-3-[(1,2-dimethyl-5-indolyl)methyl]ureaRattus norvegicus (Norway rat)Potency28.183810
N-(4-methylphenyl)-6-(1-pyrazolyl)-3-pyridinecarboxamideRattus norvegicus (Norway rat)Potency28.183810
3-(4-chloro-1,5-dimethyl-3-pyrazolyl)-4-(4-fluorophenyl)-1H-1,2,4-triazole-5-thioneRattus norvegicus (Norway rat)Potency11.904820
am 630Rattus norvegicus (Norway rat)Potency31.622810
2-(2-quinoxalinylthio)propanoic acidRattus norvegicus (Norway rat)Potency11.294720
sb 408124Rattus norvegicus (Norway rat)Potency23.735820
2-[[2-(cyclohexylamino)-2-oxoethyl]thio]benzoic acid [2-(cyclohexylamino)-2-oxoethyl] esterRattus norvegicus (Norway rat)Potency12.774820
4-[(7-methyl-2-phenyl-3-imidazo[1,2-a]pyridinyl)methyl]morpholineRattus norvegicus (Norway rat)Potency11.220210
LSM-27960Rattus norvegicus (Norway rat)Potency3.162310
2-[[[5-(2-fluoroanilino)-1,3,4-thiadiazol-2-yl]thio]methyl]isoindole-1,3-dioneRattus norvegicus (Norway rat)Potency0.010010
1-(2-methoxy-3-dibenzofuranyl)-3-(3-methylphenyl)thioureaRattus norvegicus (Norway rat)Potency0.079410
2-(3-oxo-4H-1,4-benzothiazin-2-yl)acetic acid (7-methoxy-2-oxo-1-benzopyran-4-yl)methyl esterRattus norvegicus (Norway rat)Potency28.183810
7-(2,5-dimethoxyphenyl)-5-(trifluoromethyl)-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency28.183810
N-(2-ethoxyphenyl)-2,1,3-benzothiadiazole-4-sulfonamideRattus norvegicus (Norway rat)Potency3.548110
3-pyridinecarboxylic acid [4-[heptoxy(oxo)methyl]phenyl] esterRattus norvegicus (Norway rat)Potency1.778310
N-(4-methyl-5-oxo-2-[1]benzopyrano[4,3-b]pyridinyl)-2-phenylacetamideRattus norvegicus (Norway rat)Potency28.183810
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamideRattus norvegicus (Norway rat)Potency2.511910
3-chloro-N-[3-(2-methoxyethyl)-6-sulfamoyl-1,3-benzothiazol-2-ylidene]-1-benzothiophene-2-carboxamideRattus norvegicus (Norway rat)Potency11.220210
N-(7-methyl-2-thiazolo[4,5-g][1,3]benzothiazolyl)propanamideRattus norvegicus (Norway rat)Potency28.183810
N-(1,3-dioxo-5-isoindolyl)-1,3-benzothiazole-6-carboxamideRattus norvegicus (Norway rat)Potency28.183810
4-(4-propan-2-ylphenyl)-3,4,5,6-tetrahydro-1H-benzo[h]quinazolin-2-oneRattus norvegicus (Norway rat)Potency10.000010
2-bromo-6-[1,4-dioxa-8-azaspiro[4.5]decan-8-yl(oxo)methyl]-11-pyrido[2,1-b]quinazolinoneRattus norvegicus (Norway rat)Potency11.220210
4-[[2-(cyclohexylamino)-2-oxoethyl]thio]-3-nitrobenzoic acid methyl esterRattus norvegicus (Norway rat)Potency18.169620
2-(3-methoxyphenyl)-3,5,6,7,8,9-hexahydrocyclohepta[2,3]thieno[2,4-b]pyrimidin-4-oneRattus norvegicus (Norway rat)Potency7.943310
2-phenyl-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamineRattus norvegicus (Norway rat)Potency3.162310
2-[4-(4-methoxyphenyl)-4-methyl-2,5-dioxo-1-imidazolidinyl]-N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]acetamideRattus norvegicus (Norway rat)Potency12.589310
2-(1-adamantyl)-N-[2,5-diethoxy-4-(4-morpholinyl)phenyl]acetamideRattus norvegicus (Norway rat)Potency31.622810
N-(4-tert-butylphenyl)-2-[4-(1-imidazolyl)phenoxy]acetamideRattus norvegicus (Norway rat)Potency2.511910
8-(4-methoxyphenyl)-7-methyl-3-(phenylmethyl)purine-2,6-dioneRattus norvegicus (Norway rat)Potency15.848910
3-[(2,5,6-trimethyl-4-thieno[2,3-d]pyrimidinyl)thio]-2-oxolanoneRattus norvegicus (Norway rat)Potency8.539820
3-methoxy-N-[2-(4-methoxyphenyl)-2-(1-pyrrolidinyl)ethyl]-2-naphthalenecarboxamideRattus norvegicus (Norway rat)Potency1.258910
N-[(4-chlorophenyl)methyl]-2-[[[(2-fluorophenyl)methyl-(phenylmethyl)amino]-sulfanylidenemethyl]amino]acetamideRattus norvegicus (Norway rat)Potency3.162310
7-chloro-3-[2-(1-cyclohexenyl)ethyl]-2-sulfanylidene-1H-quinazolin-4-oneRattus norvegicus (Norway rat)Potency28.183810
1,3,5-tris(4-hydroxyphenyl)-4-propyl-1h-pyrazoleRattus norvegicus (Norway rat)Potency19.952610
2-(3-methyl-1-oxo-2-isoquinolinyl)-N-(3,4,5-trimethoxyphenyl)acetamideRattus norvegicus (Norway rat)Potency12.575220
5-[2-furanyl-[4-(phenylmethyl)-1-piperidinyl]methyl]-6-thiazolo[3,2-b][1,2,4]triazololRattus norvegicus (Norway rat)Potency5.623410
2-[2-(7-methoxy-2-oxo-1H-quinolin-3-yl)ethyl]isoindole-1,3-dioneRattus norvegicus (Norway rat)Potency28.183810
1-[2,5-dimethyl-1-(2-oxolanylmethyl)-3-pyrrolyl]-2-[[5-(4-methoxyanilino)-1,3,4-thiadiazol-2-yl]thio]ethanoneRattus norvegicus (Norway rat)Potency15.848910
2,5-dimethyl-4-[[2-oxo-2-(4-phenylbutan-2-ylamino)ethyl]thio]-6-thieno[2,3-d]pyrimidinecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency10.000010
4-[3-(2-chloro-1-oxoethyl)-2,5-dimethyl-1-pyrrolyl]-1,5-dimethyl-2-phenyl-3-pyrazoloneRattus norvegicus (Norway rat)Potency8.912510
sib 1757Rattus norvegicus (Norway rat)Potency11.220210
N-(5-acetyl-4-methyl-2-thiazolyl)-2-(2,4-dichlorophenoxy)acetamideRattus norvegicus (Norway rat)Potency10.000010
fraxetinRattus norvegicus (Norway rat)Potency16.309520
quercetinRattus norvegicus (Norway rat)Potency11.269810
bilirubinRattus norvegicus (Norway rat)Potency10.000010
bergaptolRattus norvegicus (Norway rat)Potency2.511910
apigeninRattus norvegicus (Norway rat)Potency3.981110
scopoletinRattus norvegicus (Norway rat)Potency10.610110
daphnetinRattus norvegicus (Norway rat)Potency28.183810
gossypetinRattus norvegicus (Norway rat)Potency22.387210
5-hydroxy-6,8,11,14-eicosatetraenoic acidRattus norvegicus (Norway rat)Potency11.220210
kaempferolRattus norvegicus (Norway rat)Potency11.220210
prochlorperazine maleateRattus norvegicus (Norway rat)Potency7.943310
fisetinRattus norvegicus (Norway rat)Potency11.220210
3-hydroxyblancoxanthoneRattus norvegicus (Norway rat)Potency11.220210
myricetinRattus norvegicus (Norway rat)Potency0.398210
daidzeinRattus norvegicus (Norway rat)Potency0.501210
ellagic acidRattus norvegicus (Norway rat)Potency15.848910
homo-gamma-linolenylethanolamideRattus norvegicus (Norway rat)Potency2.818410
trimipramine maleateRattus norvegicus (Norway rat)Potency0.842210
ketotifen fumarateRattus norvegicus (Norway rat)Potency11.220210
2-bromoergocryptine mesylateRattus norvegicus (Norway rat)Potency28.183810
perhexiline maleateRattus norvegicus (Norway rat)Potency22.387210
phenoxybenzamine hydrochlorideRattus norvegicus (Norway rat)Potency3.981110
su 9516Rattus norvegicus (Norway rat)Potency12.589310
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acidRattus norvegicus (Norway rat)Potency14.537610
3-ethyl-2-sulfanylidene-6,7,8,9-tetrahydro-1H-pyrimido[4,5-b]quinolin-4-oneRattus norvegicus (Norway rat)Potency31.622810
N-[(4-tert-butylphenyl)methyl]-3-oxo-4H-1,4-benzoxazine-6-carboxamideRattus norvegicus (Norway rat)Potency5.011910
4-(3,4-dihydroxyphenyl)-6-[(4-fluoro-3-methylphenyl)sulfonylmethyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency0.891310
5-[(2-fluorophenyl)methyl]-6,11-dioxo-3-benzo[b][1,4]benzothiazepinecarboxylic acidRattus norvegicus (Norway rat)Potency2.238710
2,5-dimethyl-N-(3,4,5-trimethoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amineRattus norvegicus (Norway rat)Potency1.778310
N-(3,5-dimethylphenyl)-2-[[4-(4-fluorophenyl)-5-[(1-methyl-2-pyrrolyl)methyl]-1,2,4-triazol-3-yl]thio]acetamideRattus norvegicus (Norway rat)Potency22.387210
N-[(4-fluorophenyl)methyl]-2-[[4-(4-methoxyphenyl)-5-[(1-methyl-2-pyrrolyl)methyl]-1,2,4-triazol-3-yl]thio]acetamideRattus norvegicus (Norway rat)Potency19.952610
N-(2-ethoxyphenyl)-1-(8-quinolinylsulfonyl)-3-piperidinecarboxamideRattus norvegicus (Norway rat)Potency2.818410
[1-[(3,5-dimethyl-4-isoxazolyl)sulfonyl]-4-piperidinyl]-[4-(1-piperidinyl)-1-piperidinyl]methanoneRattus norvegicus (Norway rat)Potency10.000010
3-[[4-[6-(4-morpholinyl)-3-pyridazinyl]-1-piperazinyl]-oxomethyl]-1-benzopyran-2-oneRattus norvegicus (Norway rat)Potency31.622810
2-[[oxo-(5-propyl-3-isoxazolyl)methyl]amino]benzoic acid methyl esterRattus norvegicus (Norway rat)Potency11.220210
5-chloro-2-methoxy-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]-N-propan-2-ylbenzamideRattus norvegicus (Norway rat)Potency28.183810
2-(1,3-benzodioxol-5-ylmethyl)-3-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-3H-isoindol-1-oneRattus norvegicus (Norway rat)Potency0.562310
N-[4-[(4-methyl-1-piperidinyl)methyl]phenyl]-1-[5-(1-pyrrolyl)-1,3,4-thiadiazol-2-yl]-4-piperidinecarboxamideRattus norvegicus (Norway rat)Potency1.000010
4-[[2-[4-(2-chlorophenyl)-2-oxo-6,7-dihydro-5H-cyclopenta[b]pyridin-1-yl]-1-oxoethyl]amino]-1-piperidinecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency2.511910
1-(4-tert-butylphenyl)sulfonyl-N-(2-pyridinylmethyl)-2-piperidinecarboxamideRattus norvegicus (Norway rat)Potency8.912510
N-(1,3-benzodioxol-5-yl)-2-(5-methyl-2-furanyl)-3-imidazo[1,2-a]pyrazinamineRattus norvegicus (Norway rat)Potency10.000010
5-amino-1-[(3-methoxyphenyl)methyl]-N-(4-methylphenyl)-4-triazolecarboxamideRattus norvegicus (Norway rat)Potency28.183810
3-(3,5-dimethyl-1-pyrazolyl)-5-phenyl-1,2,4-triazineRattus norvegicus (Norway rat)Potency6.309610
beta-funaltrexamineRattus norvegicus (Norway rat)Potency10.000010
psb 1115Rattus norvegicus (Norway rat)Potency21.421520
(3r)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanoneRattus norvegicus (Norway rat)Potency2.511910
rosmarinic acidRattus norvegicus (Norway rat)Potency19.952610
baicalein-7-o-glucosideRattus norvegicus (Norway rat)Potency12.589310
fluvoxamineRattus norvegicus (Norway rat)Potency10.000010
ag 538Rattus norvegicus (Norway rat)Potency21.421520
ag 99Rattus norvegicus (Norway rat)Potency15.586420
tyrphostin ag 555Rattus norvegicus (Norway rat)Potency11.220210
ag 556Rattus norvegicus (Norway rat)Potency28.183810
ag 112Rattus norvegicus (Norway rat)Potency8.912510
urolithin bRattus norvegicus (Norway rat)Potency12.589320
2-(5,7-dihydroxy-4-methyl-2-oxo-1-benzopyran-3-yl)acetic acid ethyl esterRattus norvegicus (Norway rat)Potency10.000010
LSM-20631Rattus norvegicus (Norway rat)Potency0.398110
6-ethyl-7-hydroxy-4-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-1-benzopyran-2-oneRattus norvegicus (Norway rat)Potency11.220210
aztreonamRattus norvegicus (Norway rat)Potency0.004010
3,3'-di-o-methylellagic acidRattus norvegicus (Norway rat)Potency10.000010
3-(dimethylamino)benzoic acid (7-hydroxy-2-oxo-1-benzopyran-4-yl)methyl esterRattus norvegicus (Norway rat)Potency31.622810
triprolidine hydrochloride anhydrousRattus norvegicus (Norway rat)Potency3.162310
famotidineRattus norvegicus (Norway rat)Potency5.011910
quinaldine redRattus norvegicus (Norway rat)Potency4.466810
2-(dimethylaminostyryl)-1-ethylpyridiniumRattus norvegicus (Norway rat)Potency28.183810
chloride of pseudoisocyanineRattus norvegicus (Norway rat)Potency10.610120
derruboneRattus norvegicus (Norway rat)Potency11.220210
su 1498Rattus norvegicus (Norway rat)Potency5.011910
N-methyl-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amineRattus norvegicus (Norway rat)Potency7.943310
5-[(2-chlorophenyl)thio]-3-(4-methylphenyl)-1,2,4-triazine-6-carboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency2.238710
beta-zearalenolRattus norvegicus (Norway rat)Potency31.622810
su 4312Rattus norvegicus (Norway rat)Potency11.220210
protriptyline hydrochlorideRattus norvegicus (Norway rat)Potency1.122010
bay-k-8644, (-)-isomerRattus norvegicus (Norway rat)Potency0.002510
cb 34Rattus norvegicus (Norway rat)Potency10.000010
gw2974Rattus norvegicus (Norway rat)Potency11.220210
8-hydroxy-2-(di-n-propylamino)tetralin, (r)-isomerRattus norvegicus (Norway rat)Potency11.904810
l 750667Rattus norvegicus (Norway rat)Potency2.511910
3,4-dichloro-n-methyl-n-(2-(1-pyrrolidinyl)cyclohexyl)-benzeneacetamide, (trans)-(-)-isomerRattus norvegicus (Norway rat)Potency6.269710
bvt.948Rattus norvegicus (Norway rat)Potency12.924420
4-[(2,4-dioxo-1H-thieno[3,2-d]pyrimidin-3-yl)methyl]-N-(3-ethylphenyl)benzamideRattus norvegicus (Norway rat)Potency28.183810
4-methyl-N-[(4-methylphenyl)methyl]-2-furo[3,2-c]quinolinecarboxamideRattus norvegicus (Norway rat)Potency10.000010
1-(4-oxo-2-thieno[3,2-d][1,3]thiazinyl)-N-(phenylmethyl)-3-piperidinecarboxamideRattus norvegicus (Norway rat)Potency12.589310
N-(4-ethoxyphenyl)-1,5-dimethyl-4-oxo-2-pyrrolo[3,2-c]quinolinecarboxamideRattus norvegicus (Norway rat)Potency7.943310
1-cyclopropyl-3-[6-oxo-5-(phenylmethyl)-3-benzo[b][1,4]benzothiazepinyl]ureaRattus norvegicus (Norway rat)Potency10.000010
atomoxetineRattus norvegicus (Norway rat)Potency11.220210
4-fluoro-N-(4-fluoro-1,3-benzothiazol-2-yl)-1,3-benzothiazol-2-amineRattus norvegicus (Norway rat)Potency11.220210
3-(3-methylphenyl)-2-sulfanylidene-1H-benzofuro[3,2-d]pyrimidin-4-oneRattus norvegicus (Norway rat)Potency8.912510
2-[[6-(2-furanyl)-3-pyridazinyl]thio]-N-(3-methylphenyl)acetamideRattus norvegicus (Norway rat)Potency28.183810
5-Chloro-3-pyridinyl 2-furoateRattus norvegicus (Norway rat)Potency31.622810
6-(4-bromophenyl)-2-methyl-3-pyridinecarboxylic acidRattus norvegicus (Norway rat)Potency8.912510
5,7-dimethyl-3-[3-(trifluoromethyl)phenyl]azo-1H-pyrazolo[1,5-a]pyrimidin-2-oneRattus norvegicus (Norway rat)Potency4.466810
4-[[[4-[(4-fluorophenyl)methyl]-2,3-dihydro-1,4-benzothiazin-6-yl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency12.589310
2-(2-benzoyl-1-pyrrolyl)-N-methyl-N-(phenylmethyl)acetamideRattus norvegicus (Norway rat)Potency1.122010
N-[2-methyl-5-(2-oxazolo[4,5-b]pyridinyl)phenyl]-2-phenoxyacetamideRattus norvegicus (Norway rat)Potency11.220210
3-(4-ethoxyphenyl)-1-[3-(4-morpholinyl)propyl]-1-[(1-propyl-3,4-dihydro-2H-quinolin-6-yl)methyl]ureaRattus norvegicus (Norway rat)Potency2.238710
2-(1-methyl-4-oxo-3-furo[3,4]pyrrolo[3,5-c][1,2,4]triazinyl)-N-(3-phenylpropyl)propanamideRattus norvegicus (Norway rat)Potency1.258910
N-(1,3-benzodioxol-5-yl)-2-(4-methylphenyl)-3-imidazo[1,2-a]pyrazinamineRattus norvegicus (Norway rat)Potency10.000010
2-[3-(3-chlorophenyl)-5-isoxazolyl]-1-hydroxy-4H-1,2,4-benzotriazin-3-oneRattus norvegicus (Norway rat)Potency31.622810
1-cyclohexyl-3-[1-[4-(phenylmethyl)-1-piperazinyl]-1-thiophen-2-ylpropan-2-yl]ureaRattus norvegicus (Norway rat)Potency2.238710
4-[[oxo-[4-(phenylmethyl)-2,3-dihydro-1,4-benzothiazin-6-yl]methyl]amino]-1-piperidinecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency11.220210
4-methyl-N-[[4-[oxo-[4-(phenylmethyl)-1-piperazinyl]methyl]phenyl]methyl]benzenesulfonamideRattus norvegicus (Norway rat)Potency1.258910
N-(phenylmethyl)-3-[3,4,6-trimethyl-1-(4-methylphenyl)-5-pyrazolo[3,4-b]pyridinyl]propanamideRattus norvegicus (Norway rat)Potency12.589310
1-[4-(2,3-dimethylphenyl)-1-piperazinyl]-2-(1-methyl-3-indolyl)ethanoneRattus norvegicus (Norway rat)Potency1.778310
n-methylbenzylamine hydrochlorideRattus norvegicus (Norway rat)Potency2.238710
(S)-fluoxetine hydrochlorideRattus norvegicus (Norway rat)Potency11.220210
(5R)-9-bromo-5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diolRattus norvegicus (Norway rat)Potency1.584910
ucn 1028 cRattus norvegicus (Norway rat)Potency28.183810
2-(2,1,3-benzothiadiazol-4-ylsulfonylamino)-N-(6-methoxy-1,3-benzothiazol-2-yl)-3-methylbutanamideRattus norvegicus (Norway rat)Potency28.183810
dsp 4 hydrochlorideRattus norvegicus (Norway rat)Potency11.220210
1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochlorideRattus norvegicus (Norway rat)Potency0.891310
N-[5-[2-(2,5-dimethoxyanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]-2-methylpentanamideRattus norvegicus (Norway rat)Potency25.118910
N-(1-adamantylmethyl)-2-ethyl-3-methoxy-6-indazolecarboxamideRattus norvegicus (Norway rat)Potency28.183810
N-[4-(diethylamino)-2-methylphenyl]-2-[(2-nitro-3-thiophenyl)thio]acetamideRattus norvegicus (Norway rat)Potency7.943310
3-(benzenesulfonyl)-N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]propanamideRattus norvegicus (Norway rat)Potency12.589310
1-[(4-methylphenyl)methyl]-2,4-dioxo-N-(phenylmethyl)-3-prop-2-enyl-7-quinazolinecarboxamideRattus norvegicus (Norway rat)Potency22.387210
2-[[3-(3,4-dimethoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]thio]-N-(5-methyl-3-isoxazolyl)acetamideRattus norvegicus (Norway rat)Potency28.183810
N-[[2-(4-methylphenyl)-1,3-dioxo-7,7a-dihydro-3aH-octahydro-1H-4,7-epoxyisoindol-4-yl]methyl]-4-phenyl-1-piperazinecarbothioamideRattus norvegicus (Norway rat)Potency28.183810
N-[2-[4-(4-methoxyphenyl)-1-piperazinyl]ethyl]-6-sulfanylidene-5H-benzimidazolo[1,2-c]quinazoline-3-carboxamideRattus norvegicus (Norway rat)Potency14.125410
machilin dRattus norvegicus (Norway rat)Potency0.501210
phenylmercuric acetateRattus norvegicus (Norway rat)Potency11.220210
acid blue 129Rattus norvegicus (Norway rat)Potency22.740620
oxytetracycline hydrochlorideRattus norvegicus (Norway rat)Potency24.905420
LSM-23565Rattus norvegicus (Norway rat)Potency12.589310
hispidinRattus norvegicus (Norway rat)Potency11.220210
demeclocycline hydrochlorideRattus norvegicus (Norway rat)Potency3.981110
7-chloro-3-[cyclopropyl(oxo)methyl]-4-hydroxy-1H-quinolin-2-oneRattus norvegicus (Norway rat)Potency22.387210
4-hydroxy-N-(2-methyl-4-oxo-3-quinazolinyl)-1-(2-methylpropyl)-2-oxo-5,6,7,8-tetrahydroquinoline-3-carboxamideRattus norvegicus (Norway rat)Potency0.631010
clozapineRattus norvegicus (Norway rat)Potency5.045110
dacarbazineRattus norvegicus (Norway rat)Potency6.309610
olanzapineRattus norvegicus (Norway rat)Potency8.912510
hemateinRattus norvegicus (Norway rat)Potency11.904820
norclozapineRattus norvegicus (Norway rat)Potency5.833410
2-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-1H-quinazolin-4-oneRattus norvegicus (Norway rat)Potency5.011910
ag-879Rattus norvegicus (Norway rat)Potency5.623410
2-[(4-methoxyphenyl)methylthio]-6-methyl-1H-pyrimidin-4-oneRattus norvegicus (Norway rat)Potency5.011910
1-[4-[[(5-methyl-7-oxo-4H-isothiazolo[4,3-d]pyrimidin-3-yl)-oxomethyl]amino]phenyl]-3-piperidinecarboxylic acid ethyl esterRattus norvegicus (Norway rat)Potency7.943310
2-[(5-cyano-4-oxo-6-phenyl-1H-pyrimidin-2-yl)thio]-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamideRattus norvegicus (Norway rat)Potency11.220210
LSM-20825Rattus norvegicus (Norway rat)Potency28.183810
2-[(5-cyano-4-oxo-6-phenyl-1H-pyrimidin-2-yl)thio]-N-phenylacetamideRattus norvegicus (Norway rat)Potency8.764920
2-[[2-[(5-cyano-4-oxo-6-phenyl-1H-pyrimidin-2-yl)thio]-1-oxoethyl]amino]-4-methylpentanoic acid methyl esterRattus norvegicus (Norway rat)Potency10.750920