Page last updated: 2024-08-07 22:55:44

nuclear factor NF-kappa-B p105 subunit isoform 1

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (193)

Drugs with Potency Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
chlordeconeHomo sapiens (human)Potency40.074810
4-aminophenolHomo sapiens (human)Potency35.481310
1,4-dihydroxy-2-naphthoic acidHomo sapiens (human)Potency31.622810
pentachlorophenolHomo sapiens (human)Potency11.220210
N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenamideHomo sapiens (human)Potency44.668410
4-nonylphenolHomo sapiens (human)Potency44.668410
bithionolHomo sapiens (human)Potency50.118710
clioquinolHomo sapiens (human)Potency17.782810
ddtHomo sapiens (human)Potency44.668410
dichlorophenHomo sapiens (human)Potency11.220210
dichlorvosHomo sapiens (human)Potency7.191210
ethacrynic acidHomo sapiens (human)Potency44.668410
fenvalerateHomo sapiens (human)Potency39.810710
gossypolHomo sapiens (human)Potency44.668410
hexachloropheneHomo sapiens (human)Potency50.118710
malathionHomo sapiens (human)Potency31.622810
methyl parathionHomo sapiens (human)Potency8.912510
mitotaneHomo sapiens (human)Potency44.668410
stearic acidHomo sapiens (human)Potency0.014110
thiramHomo sapiens (human)Potency31.622810
triamtereneHomo sapiens (human)Potency42.239510
reserpineHomo sapiens (human)Potency42.239510
cetrimonium bromideHomo sapiens (human)Potency50.118710
chlordanHomo sapiens (human)Potency70.794610
9,10-dimethyl-1,2-benzanthraceneHomo sapiens (human)Potency34.893610
promethazine hydrochlorideHomo sapiens (human)Potency25.118910
androstenedioneHomo sapiens (human)Potency31.622810
cycloheximideHomo sapiens (human)Potency0.295110
chlorpromazine hydrochlorideHomo sapiens (human)Potency44.668410
dichlorodiphenyldichloroethaneHomo sapiens (human)Potency44.668410
1,1,2-trichloroethaneHomo sapiens (human)Potency0.089110
acenaphtheneHomo sapiens (human)Potency50.118710
1-naphthylphenylamineHomo sapiens (human)Potency50.118710
2-phenylphenolHomo sapiens (human)Potency251.189010
uvitex swnHomo sapiens (human)Potency39.810710
4,4'-thiobis(6-tert-butyl-3-cresol)Homo sapiens (human)Potency33.997210
dimethyl-4-phenylenediamineHomo sapiens (human)Potency44.668410
2-vinylpyridineHomo sapiens (human)Potency50.118710
dyreneHomo sapiens (human)Potency25.118910
4,4'-diphenylmethane diisocyanateHomo sapiens (human)Potency31.622810
dicyclohexylamineHomo sapiens (human)Potency50.118710
diphenylguanidineHomo sapiens (human)Potency44.668410
lauric acid methyl esterHomo sapiens (human)Potency39.810710
imipramine hydrochlorideHomo sapiens (human)Potency35.481310
dicofolHomo sapiens (human)Potency44.668410
dichloneHomo sapiens (human)Potency39.810710
chloranilHomo sapiens (human)Potency44.668410
2,2'-methylenebis(4-methyl-6-tert-butylphenol)Homo sapiens (human)Potency28.183810
benzethonium chlorideHomo sapiens (human)Potency42.239510
captanHomo sapiens (human)Potency35.716810
ziramHomo sapiens (human)Potency21.169910
4-nitrosodimethylanilineHomo sapiens (human)Potency35.481310
4'-(chloroacetyl)acetanilideHomo sapiens (human)Potency19.952610
sulfurous acid, 2-(p-tert-butylphenoxy)-1-methylethyl 2-chloroethyl esterHomo sapiens (human)Potency50.118710
4-tert-octylphenolHomo sapiens (human)Potency39.810710
1,12-benzoperyleneHomo sapiens (human)Potency39.810710
benzo(b)fluorantheneHomo sapiens (human)Potency44.668410
fluorantheneHomo sapiens (human)Potency50.118710
benzo(k)fluorantheneHomo sapiens (human)Potency5.773210
lithocholic acidHomo sapiens (human)Potency50.118710
naphthol yellowHomo sapiens (human)Potency50.118710
domiphen bromideHomo sapiens (human)Potency50.118710
gentian violetHomo sapiens (human)Potency35.716810
amitriptyline hydrochlorideHomo sapiens (human)Potency40.870810
2-anthramineHomo sapiens (human)Potency31.622810
Berberine chloride (TN)Homo sapiens (human)Potency25.118910
n-(1,3-dimethylbutyl)-n'-phenyl-1,4-phenylenediamineHomo sapiens (human)Potency50.118710
ethidium bromideHomo sapiens (human)Potency22.387210
4-octylphenolHomo sapiens (human)Potency50.118710
tetrachloroisophthalonitrileHomo sapiens (human)Potency28.183810
pimozideHomo sapiens (human)Potency35.481310
captafolHomo sapiens (human)Potency39.810710
pentaerythrityl triacrylateHomo sapiens (human)Potency32.464810
mono-(2-ethylhexyl)phthalateHomo sapiens (human)Potency56.234110
methylene bis(thiocyanate)Homo sapiens (human)Potency42.239510
2,2-dibromo-3-nitrilopropionamideHomo sapiens (human)Potency44.668410
1,6-hexanediol diacrylateHomo sapiens (human)Potency19.952610
pyrithione zincHomo sapiens (human)Potency39.810710
tetraethylene glycol diacrylateHomo sapiens (human)Potency17.900810
isopropyl 4,4'-dibromobenzilateHomo sapiens (human)Potency44.668410
2-(thiocyanomethylthio)benzothiazoleHomo sapiens (human)Potency44.668410
tris(2,3-dibromopropyl)phosphateHomo sapiens (human)Potency44.668410
tributyl phosphateHomo sapiens (human)Potency56.234110
butylated hydroxytolueneHomo sapiens (human)Potency39.810710
2,4,5,2',4',5'-hexachlorobiphenylHomo sapiens (human)Potency50.118710
oxyfluorofenHomo sapiens (human)Potency15.848910
decamethrinHomo sapiens (human)Potency39.810710
bromethalinHomo sapiens (human)Potency35.481310
raloxifene hydrochlorideHomo sapiens (human)Potency44.668410
saquinavir monomethanesulfonateHomo sapiens (human)Potency50.118710
octyl gallateHomo sapiens (human)Potency50.118710
daunorubicin hydrochlorideHomo sapiens (human)Potency44.668410
epigallocatechin gallateHomo sapiens (human)Potency12.589310
econazole nitrateHomo sapiens (human)Potency22.387210
crystal violet lactoneHomo sapiens (human)Potency15.848910
9,9-bis(4-hydroxyphenyl)fluoreneHomo sapiens (human)Potency50.118710
fluazinamHomo sapiens (human)Potency44.668410
famoxadoneHomo sapiens (human)Potency31.622810
methylmercuric chlorideHomo sapiens (human)Potency39.810710
ochratoxin aHomo sapiens (human)Potency44.668410
doxorubicin hydrochlorideHomo sapiens (human)Potency44.668410
5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diolHomo sapiens (human)Potency44.668410
t0901317Homo sapiens (human)Potency50.118710
afimoxifeneHomo sapiens (human)Potency28.183810
ketoconazoleHomo sapiens (human)Potency44.668410
riboflavinHomo sapiens (human)Potency44.668410
fumaronitrileHomo sapiens (human)Potency39.810710
curcuminHomo sapiens (human)Potency50.118710
malachite greenHomo sapiens (human)Potency39.810710
tamoxifen citrateHomo sapiens (human)Potency47.393610
tetraoctylammonium bromideHomo sapiens (human)Potency25.118910
zuclomifene citrateHomo sapiens (human)Potency44.668410
1,8-dinitro-4,5-dihydroxyanthraquinoneHomo sapiens (human)Potency17.782810
coumestrolHomo sapiens (human)Potency39.810710
hydramethylnonHomo sapiens (human)Potency25.118910
afimoxifeneHomo sapiens (human)Potency50.118710
fenretinideHomo sapiens (human)Potency39.810710
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acidHomo sapiens (human)Potency44.668410
5,7-dihydroxy-4-methylcoumarinHomo sapiens (human)Potency50.118710
methylbenzethonium chlorideHomo sapiens (human)Potency44.668410
cyhexatinHomo sapiens (human)Potency31.622810
triphenyltin hydroxideHomo sapiens (human)Potency39.810710
pyrachlostrobinHomo sapiens (human)Potency39.810710
avermectin b(1)aHomo sapiens (human)Potency17.782810
pregna-4,17-diene-3,16-dioneHomo sapiens (human)Potency50.118710
chlorhexidineHomo sapiens (human)Potency50.118710
6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde o-(3,4-dichlorobenzyl)oximeHomo sapiens (human)Potency39.810710
flonicamidHomo sapiens (human)Potency50.118710
pydrin, (s-(r*,r*))-isomerHomo sapiens (human)Potency50.118710
phenylmercuric acetateHomo sapiens (human)Potency11.904810
bis(tri-n-butyltin)oxideHomo sapiens (human)Potency28.183810
thimerosalHomo sapiens (human)Potency35.481310

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
indoprofenHomo sapiens (human)EC501.518010
frentizoleHomo sapiens (human)EC500.899010
efuamideHomo sapiens (human)EC509,069.820010
1,4-di(2'-thienyl)-1,4-butadioneHomo sapiens (human)EC50227.894010
N-(4-methoxyphenyl)-1,3-benzothiazol-2-amineHomo sapiens (human)EC5020.378010
DubamineHomo sapiens (human)EC5016.743010
resveratrolHomo sapiens (human)EC505.203010
N-[4-(diethylamino)phenyl]-2-furancarboxamideHomo sapiens (human)EC502.499010
6-methoxy-2-(4-methoxyphenyl)-1-benzopyran-4-oneHomo sapiens (human)EC503.918010
vu0038882Homo sapiens (human)EC505.562010
N-(4-methoxyphenyl)-2-benzofurancarboxamideHomo sapiens (human)EC50142.792010
1-(1,3-benzothiazol-2-yl)-3-phenylureaHomo sapiens (human)EC5027.210010
N-[[(6-methyl-1,3-benzothiazol-2-yl)amino]-sulfanylidenemethyl]-2-thiophenecarboxamideHomo sapiens (human)EC502.227010
nsc185058Homo sapiens (human)EC502.028010
2-[(2-fluorophenyl)methylthio]-5-(4-methylphenyl)-1,3,4-oxadiazoleHomo sapiens (human)EC504.629010
N-[3-chloro-4-(1-pyrrolidinyl)phenyl]-2-furancarboxamideHomo sapiens (human)EC501.677010
N-[4-(2-methyl-4-thiazolyl)phenyl]benzamideHomo sapiens (human)EC500.761010
5-bromo-N-(4-propan-2-ylphenyl)-2-furancarboxamideHomo sapiens (human)EC501.707010
6-(1,3-benzoxazol-2-yl)-1,3-benzothiazol-2-amineHomo sapiens (human)EC501.387010
6-(4-chlorophenyl)-2-methyl-3-pyridinecarboxylic acid methyl esterHomo sapiens (human)EC504.442010
2-methyl-N-(2-naphthalenyl)-3-furancarboxamideHomo sapiens (human)EC503.700010
3-[[(3-chloro-4-ethoxyphenyl)-oxomethyl]amino]benzoic acidHomo sapiens (human)EC5047.807010
2-methoxy-N-(4-methylphenyl)-4-(methylthio)benzamideHomo sapiens (human)EC503.047010
1-cyclohexyl-3-(2,3-dihydro-1,4-benzodioxin-6-yl)ureaHomo sapiens (human)EC5018.205010
5-methyl-1-phenyl-4-pyrazolecarboxylic acid (4-methoxyphenyl) esterHomo sapiens (human)EC5049.524010
N-(2-phenyl-6-imidazo[1,2-a]pyridinyl)acetamideHomo sapiens (human)EC502.699010
benzoic acid (2-oxo-2-thiophen-2-ylethyl) esterHomo sapiens (human)EC5012.559010
3-(4-methoxyphenyl)-5-(4-methylphenyl)-1,2,4-oxadiazoleHomo sapiens (human)EC509,038.190010
N2-(4-methylphenyl)-6-[(2-pyrimidinylthio)methyl]-1,3,5-triazine-2,4-diamineHomo sapiens (human)EC508,804.660010
4-[methyl-(4-thiophen-2-yl-2-thiazolyl)amino]phenolHomo sapiens (human)EC503.855010
N-(3-chloro-4-methylphenyl)-2-(2-formylphenoxy)acetamideHomo sapiens (human)EC503.883010
3-[2-(4-aminoanilino)-4-thiazolyl]-1-benzopyran-2-oneHomo sapiens (human)EC502.019010
N-[4-[2-[(6-methyl-2-pyridinyl)amino]-4-thiazolyl]phenyl]acetamideHomo sapiens (human)EC501.000010
1-(4-bromophenyl)-4-[1-naphthalenyl(oxo)methyl]-3-pyrazolecarboxylic acid ethyl esterHomo sapiens (human)EC503.002010
N-(4-methylphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamideHomo sapiens (human)EC5010.395010
4-(5-amino-4-phenyl-1-pyrazolyl)benzoic acidHomo sapiens (human)EC5046.238010
N-[5-(4-tert-butylphenyl)-1,3,4-thiadiazol-2-yl]-2-methoxyacetamideHomo sapiens (human)EC5011.027010
N-(2,3-dihydro-1H-inden-5-yl)-5-methyl-2-pyrazinecarboxamideHomo sapiens (human)EC502.454010
4-(4-chlorophenyl)-1-(6-fluoro-2-pyridinyl)-3-pyrazolamineHomo sapiens (human)EC500.675010
N-[3-[[diethylamino(sulfanylidene)methyl]thio]-1-oxopropyl]carbamic acid (4-propan-2-ylphenyl) esterHomo sapiens (human)EC501.553010
N-[3-[[diethylamino(sulfanylidene)methyl]thio]-1-oxopropyl]carbamic acid (4-methylphenyl) esterHomo sapiens (human)EC501.928010
N-[3-[[diethylamino(sulfanylidene)methyl]thio]-1-oxopropyl]carbamic acid (4-tert-butylphenyl) esterHomo sapiens (human)EC503.632010
3-hydroxybenzoic acid [2-(1H-indol-3-yl)-2-oxoethyl] esterHomo sapiens (human)EC5014.620010
2-nitrobenzoic acid [1-(4-methylphenyl)-1-oxopropan-2-yl] esterHomo sapiens (human)EC509.076010
N-(2-methoxy-3-dibenzofuranyl)-2-oxolanecarboxamideHomo sapiens (human)EC505.782010
6-[(phenylmethylthio)methyl]imidazo[2,1-b]thiazoleHomo sapiens (human)EC5012.577010
4-amino-2-(butylthio)-5-pyrimidinecarboxylic acid ethyl esterHomo sapiens (human)EC5046.227010
4-[(1-methyl-2-oxo-4-quinolinyl)oxy]-N-(4-methyl-2-pyridinyl)butanamideHomo sapiens (human)EC5010.469010
7-[(4-methyl-1-piperazinyl)methyl]-5-(phenylmethoxymethyl)-8-quinolinolHomo sapiens (human)EC5011.024010
N,N-dimethylcarbamodithioic acid (1-acetamido-2,2,2-trichloroethyl) esterHomo sapiens (human)EC500.059010
2-(4-phenyl-1-piperazinyl)quinoxalineHomo sapiens (human)EC501.613010
3-(5-bromo-2-furanyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazoleHomo sapiens (human)EC502.011010
3-[(4-methoxyphenoxy)methyl]-N-(4-nitro-1-pyrazolyl)benzamideHomo sapiens (human)EC506,456.810010
biochanin aHomo sapiens (human)EC5055.941010
5,7-dihydroxy-4',6-dimethoxyflavoneHomo sapiens (human)EC502.290010
7,4'-dimethoxy-5-hydroxyisoflavoneHomo sapiens (human)EC501.725010
5-methoxy-3,6-diphenyl-1,2,4-triazineHomo sapiens (human)EC5038.932010
N-methyl-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amineHomo sapiens (human)EC50102.034010
1-(1,3-benzodioxol-5-yl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)ureaHomo sapiens (human)EC500.114010
2-chloro-3-[2-(4-methylphenyl)-5-tetrazolyl]pyridineHomo sapiens (human)EC504.752010
kf38789Homo sapiens (human)EC502.328010