| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Nasopharyngeal Carcinoma
A carcinoma that originates in the EPITHELIUM of the NASOPHARYNX and includes four subtypes: keratinizing squamous cell, non-keratinizing, basaloid squamous cell, and PAPILLARY ADENOCARCINOMA. It is most prevalent in Southeast Asian populations and is associated with EPSTEIN-BARR VIRUS INFECTIONS. Somatic mutations associated with this cancer have been identified in NPCR, BAP1, UBAP1, ERBB2, ERBB3, MLL2, PIK3CA, KRAS, NRAS, and ARID1A genes. | 0 | 2.41 | 1 | 0 |
Cancer of Nasopharynx
[description not available] | 0 | 2.41 | 1 | 0 |
Nasopharyngeal Neoplasms
Tumors or cancer of the NASOPHARYNX. | 0 | 2.41 | 1 | 0 |
Glial Cell Tumors
[description not available] | 0 | 2.6 | 1 | 0 |
Glioma
Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21) | 0 | 2.6 | 1 | 0 |
Anoxemia
[description not available] | 0 | 4.27 | 6 | 0 |
Astrocytoma, Grade IV
[description not available] | 0 | 2.6 | 1 | 0 |
Hypoxia
Sub-optimal OXYGEN levels in the ambient air of living organisms. | 0 | 4.27 | 6 | 0 |
Glioblastoma
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 1 | 4.6 | 1 | 0 |
Benign Neoplasms
[description not available] | 0 | 4.36 | 18 | 0 |
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 4.36 | 18 | 0 |
Cancer of the Thyroid
[description not available] | 0 | 2.21 | 1 | 0 |
Thyroid Neoplasms
Tumors or cancer of the THYROID GLAND. | 0 | 2.21 | 1 | 0 |
Cancer of Ovary
[description not available] | 0 | 3.11 | 4 | 0 |
Ovarian Neoplasms
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. | 0 | 3.11 | 4 | 0 |
Breast Cancer
[description not available] | 0 | 3.36 | 6 | 0 |
Breast Neoplasms
Tumors or cancer of the human BREAST. | 0 | 3.36 | 6 | 0 |
Cancer of Prostate
[description not available] | 0 | 2.59 | 2 | 0 |
Prostatic Neoplasms
Tumors or cancer of the PROSTATE. | 0 | 2.59 | 2 | 0 |
Experimental Neoplasms
[description not available] | 0 | 2.47 | 2 | 0 |
Encephalopathy, Traumatic
[description not available] | 0 | 3.48 | 2 | 0 |
Hemorrhagic Shock
[description not available] | 0 | 3.39 | 2 | 0 |
Brain Injuries, Traumatic
A form of acquired brain injury which occurs when a sudden trauma causes damage to the brain. | 0 | 3.48 | 2 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 4.02 | 13 | 0 |
Cell Transformation, Neoplastic
Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill. | 0 | 2.17 | 1 | 0 |
Bleeding
[description not available] | 0 | 2.17 | 1 | 0 |
Hemorrhage
Bleeding or escape of blood from a vessel. | 0 | 2.17 | 1 | 0 |
B16 Melanoma
[description not available] | 0 | 2.21 | 1 | 0 |
Apoplexy
[description not available] | 0 | 5.51 | 5 | 1 |
Cerebral Ischemia
[description not available] | 0 | 6.21 | 4 | 1 |
Brain Ischemia
Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION. | 0 | 6.21 | 4 | 1 |
Stroke
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810) | 0 | 5.51 | 5 | 1 |
Anterior Choroidal Artery Infarction
[description not available] | 0 | 2.08 | 1 | 0 |
Cerebral Infarction
The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction). | 0 | 2.08 | 1 | 0 |
Extravascular Hemolysis
[description not available] | 0 | 3 | 4 | 0 |
Hemolysis
The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity. | 0 | 3 | 4 | 0 |
Heart Disease, Ischemic
[description not available] | 0 | 3.84 | 4 | 0 |
Myocardial Ischemia
A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION). | 0 | 3.84 | 4 | 0 |
Fibroadenoma
An adenoma containing fibrous tissue. It should be differentiated from ADENOFIBROMA which is a tumor composed of connective tissue (fibroma) containing glandular (adeno-) structures. (From Dorland, 27th ed) | 0 | 2.1 | 1 | 0 |
Cardiovascular Stroke
[description not available] | 0 | 2.42 | 2 | 0 |
Injury, Myocardial Reperfusion
[description not available] | 0 | 2.1 | 1 | 0 |
Myocardial Infarction
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). | 0 | 2.42 | 2 | 0 |
Anterior Cerebral Circulation Infarction
[description not available] | 0 | 2.11 | 1 | 0 |
Brain Infarction
Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis. | 0 | 2.11 | 1 | 0 |
Bends
[description not available] | 0 | 2.11 | 1 | 0 |
Absence Seizure
[description not available] | 0 | 2.11 | 1 | 0 |
Seizures
Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder. | 0 | 2.11 | 1 | 0 |
Cerebral Infarction, Middle Cerebral Artery
[description not available] | 0 | 2.11 | 1 | 0 |
Brain Hemorrhage, Cerebral
[description not available] | 0 | 2.49 | 2 | 0 |
Injury, Ischemia-Reperfusion
[description not available] | 0 | 2.11 | 1 | 0 |
ACA Infarct
[description not available] | 0 | 2.11 | 1 | 0 |
Cerebral Hemorrhage
Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA. | 0 | 2.49 | 2 | 0 |
Reperfusion Injury
Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA. | 0 | 2.11 | 1 | 0 |
Infarction, Middle Cerebral Artery
NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction. | 0 | 2.11 | 1 | 0 |
Cancer of Pancreas
[description not available] | 0 | 2.11 | 1 | 0 |
Pancreatic Neoplasms
Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA). | 0 | 2.11 | 1 | 0 |
Wet Macular Degeneration
A form of RETINAL DEGENERATION in which abnormal CHOROIDAL NEOVASCULARIZATION occurs under the RETINA and MACULA LUTEA, causing bleeding and leaking of fluid. This leads to bulging and or lifting of the macula and the distortion or destruction of central vision. | 0 | 2.13 | 1 | 0 |
Cancer of Colon
[description not available] | 0 | 2.15 | 1 | 0 |
Colonic Neoplasms
Tumors or cancer of the COLON. | 0 | 2.15 | 1 | 0 |
Rheumatoid Arthritis
[description not available] | 0 | 2.15 | 1 | 0 |
Arthritis, Rheumatoid
A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. | 0 | 2.15 | 1 | 0 |
Calcification, Pathologic
[description not available] | 0 | 3 | 1 | 0 |
Abnormality, Heart
[description not available] | 0 | 3 | 1 | 0 |
Autosomal Chromosome Disorders
[description not available] | 0 | 3 | 1 | 0 |
Calcinosis
Pathologic deposition of calcium salts in tissues. | 0 | 3 | 1 | 0 |
Heart Defects, Congenital
Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life. | 0 | 3 | 1 | 0 |
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. | 0 | 3 | 1 | 0 |
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) | 0 | 6.88 | 5 | 2 |
Liver Dysfunction
[description not available] | 0 | 3.79 | 2 | 1 |
Liver Diseases
Pathological processes of the LIVER. | 0 | 3.79 | 2 | 1 |
Anemia
A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN. | 0 | 2.03 | 1 | 0 |
Carcinoma, Anaplastic
[description not available] | 0 | 1.98 | 1 | 0 |
Hepatocellular Carcinoma
[description not available] | 0 | 4.07 | 3 | 1 |
Cancer of Kidney
[description not available] | 0 | 1.98 | 1 | 0 |
Cancer of Liver
[description not available] | 0 | 4.07 | 3 | 1 |
Carcinoma
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer. | 0 | 1.98 | 1 | 0 |
Carcinoma, Hepatocellular
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. | 0 | 4.07 | 3 | 1 |
Kidney Neoplasms
Tumors or cancers of the KIDNEY. | 0 | 1.98 | 1 | 0 |
Liver Neoplasms
Tumors or cancer of the LIVER. | 0 | 4.07 | 3 | 1 |
Blood Clot
[description not available] | 0 | 2.4 | 2 | 0 |
Thrombosis
Formation and development of a thrombus or blood clot in the blood vessel. | 0 | 2.4 | 2 | 0 |
Renal Artery Stenosis
[description not available] | 0 | 3.38 | 1 | 1 |
Renal Artery Obstruction
Narrowing or occlusion of the RENAL ARTERY or arteries. It is due usually to ATHEROSCLEROSIS; FIBROMUSCULAR DYSPLASIA; THROMBOSIS; EMBOLISM, or external pressure. The reduced renal perfusion can lead to renovascular hypertension (HYPERTENSION, RENOVASCULAR). | 0 | 3.38 | 1 | 1 |
Basilar Artery Insufficiency
[description not available] | 0 | 2.91 | 1 | 0 |
Carotid Artery Narrowing
[description not available] | 0 | 4.7 | 2 | 1 |
Carotid Stenosis
Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3) | 0 | 4.7 | 2 | 1 |
Coronary Heart Disease
[description not available] | 0 | 1.99 | 1 | 0 |
Cardiac Diseases
[description not available] | 0 | 4.7 | 2 | 1 |
Coronary Disease
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. | 0 | 1.99 | 1 | 0 |
Heart Diseases
Pathological conditions involving the HEART including its structural and functional abnormalities. | 0 | 4.7 | 2 | 1 |
Ache
[description not available] | 0 | 1.99 | 1 | 0 |
Pain
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS. | 0 | 1.99 | 1 | 0 |
Breast Diseases
Pathological processes of the BREAST. | 0 | 1.99 | 1 | 0 |
Left Ventricular Dysfunction
[description not available] | 0 | 4.35 | 2 | 2 |
Ventricular Dysfunction, Left
A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall. | 0 | 4.35 | 2 | 2 |
Angioma, Cavernous
A tumor-like mass with large vascular space that is filled with blood or lymph. | 0 | 3.38 | 1 | 1 |
Cardiac Failure
[description not available] | 0 | 3.39 | 1 | 1 |
Obstructive Lung Diseases
[description not available] | 0 | 3.39 | 1 | 1 |
Heart Failure
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION. | 0 | 3.39 | 1 | 1 |
Lung Diseases, Obstructive
Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent. | 0 | 3.39 | 1 | 1 |
Experimental Hepatoma
[description not available] | 0 | 2.01 | 1 | 0 |
Adhesions, Tissue
[description not available] | 0 | 1.95 | 1 | 0 |
Bleb
[description not available] | 0 | 1.95 | 1 | 0 |
Cataract, Membranous
[description not available] | 0 | 1.95 | 1 | 0 |
Leukoma
[description not available] | 0 | 1.95 | 1 | 0 |
Cataract
Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed) | 0 | 1.95 | 1 | 0 |
Corneal Opacity
Disorder occurring in the central or peripheral area of the cornea. The usual degree of transparency becomes relatively opaque. | 0 | 1.95 | 1 | 0 |
Glaucoma
An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed) | 0 | 1.95 | 1 | 0 |