Compounds > pyrovalerone
Page last updated: 2024-09-21

pyrovalerone

Description

pyrovalerone: RN given refers to parent cpd; synonyms F 1983 & Centroton refer to HCl; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID14373
CHEMBL ID201960
CHEBI ID134998
SCHEMBL ID164376
MeSH IDM0047465

Synonyms (32)

Synonym
dea no. 1485
pyrovalerone
CHEBI:134998
1-(4-methylphenyl)-2-pyrrolidin-1-ylpentan-1-one
CHEMBL201960 ,
j8.659b ,
1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one
bdbm50182555
1-pentanone, 1-(4-methylphenyl)-2-(1-pyrrolidinyl)-
pirovalerona [inn-spanish]
pyrovaleronum
vou69c02jp ,
pyrovaleronum [inn-latin]
unii-vou69c02jp
3563-49-3
pyrovalerone [inn]
4'-methyl-2-(1-pyrrolidinyl)valerophenone
pirovalerona
pyrovalerone [who-dd]
pyrovalerone [mi]
valerophenone, 4'-methyl-2-(1-pyrrolidinyl)-
1-p-tolyl-1-oxo-2-pyrrolidino-n-pentane
pyrovalerone [mart.]
SCHEMBL164376
1-(4-methylphenyl)-2-(1-pyrrolidinyl)-1-pentanone #
SWUVZKWCOBGPTH-UHFFFAOYSA-N
4'-methyl-alpha-pyrrolidinovalerophenone
HY-U00296
CS-7265
Q410824
DTXSID20863194
1-(4-methylphenyl)-2-(pyrrolidin-1-yl)pentan-1-one

Research Excerpts

Overview

ExcerptReference
"The pyrovalerone derivatives are a branch of synthetic cathinones, a very popular group of psychostimulant NPS."( Andrzejczak, D; Wojcieszak, J; Woldan-Tambor, A; Zawilska, JB, 2016)

Drug Classes (1)

ClassDescription
aromatic ketoneA ketone in which the carbonyl group is attached to an aromatic ring.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (3)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Sodium-dependent noradrenaline transporter Homo sapiens (human)IC50 (µMol)0.02830.00081.541620.0000AID261029
Sodium-dependent noradrenaline transporter Homo sapiens (human)Ki0.19500.00031.465610.0000AID261028
Sodium-dependent serotonin transporterHomo sapiens (human)IC50 (µMol)2.78000.00010.86458.7096AID261027
Sodium-dependent serotonin transporterHomo sapiens (human)Ki3.77000.00000.70488.1930AID261026
Sodium-dependent dopamine transporter Homo sapiens (human)IC50 (µMol)0.04200.00071.841946.0000AID261025; AID420092
Sodium-dependent dopamine transporter Homo sapiens (human)Ki0.01470.00021.11158.0280AID261024; AID420091
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (55)

Processvia Protein(s)Taxonomy
monoamine transportSodium-dependent noradrenaline transporter Homo sapiens (human)
neurotransmitter transportSodium-dependent noradrenaline transporter Homo sapiens (human)
chemical synaptic transmissionSodium-dependent noradrenaline transporter Homo sapiens (human)
response to xenobiotic stimulusSodium-dependent noradrenaline transporter Homo sapiens (human)
response to painSodium-dependent noradrenaline transporter Homo sapiens (human)
norepinephrine uptakeSodium-dependent noradrenaline transporter Homo sapiens (human)
neuron cellular homeostasisSodium-dependent noradrenaline transporter Homo sapiens (human)
amino acid transportSodium-dependent noradrenaline transporter Homo sapiens (human)
norepinephrine transportSodium-dependent noradrenaline transporter Homo sapiens (human)
dopamine uptake involved in synaptic transmissionSodium-dependent noradrenaline transporter Homo sapiens (human)
sodium ion transmembrane transportSodium-dependent noradrenaline transporter Homo sapiens (human)
monoamine transportSodium-dependent serotonin transporterHomo sapiens (human)
response to hypoxiaSodium-dependent serotonin transporterHomo sapiens (human)
neurotransmitter transportSodium-dependent serotonin transporterHomo sapiens (human)
response to nutrientSodium-dependent serotonin transporterHomo sapiens (human)
memorySodium-dependent serotonin transporterHomo sapiens (human)
circadian rhythmSodium-dependent serotonin transporterHomo sapiens (human)
response to xenobiotic stimulusSodium-dependent serotonin transporterHomo sapiens (human)
response to toxic substanceSodium-dependent serotonin transporterHomo sapiens (human)
positive regulation of gene expressionSodium-dependent serotonin transporterHomo sapiens (human)
positive regulation of serotonin secretionSodium-dependent serotonin transporterHomo sapiens (human)
negative regulation of cerebellar granule cell precursor proliferationSodium-dependent serotonin transporterHomo sapiens (human)
negative regulation of synaptic transmission, dopaminergicSodium-dependent serotonin transporterHomo sapiens (human)
response to estradiolSodium-dependent serotonin transporterHomo sapiens (human)
social behaviorSodium-dependent serotonin transporterHomo sapiens (human)
vasoconstrictionSodium-dependent serotonin transporterHomo sapiens (human)
sperm ejaculationSodium-dependent serotonin transporterHomo sapiens (human)
negative regulation of neuron differentiationSodium-dependent serotonin transporterHomo sapiens (human)
positive regulation of cell cycleSodium-dependent serotonin transporterHomo sapiens (human)
negative regulation of organ growthSodium-dependent serotonin transporterHomo sapiens (human)
behavioral response to cocaineSodium-dependent serotonin transporterHomo sapiens (human)
enteric nervous system developmentSodium-dependent serotonin transporterHomo sapiens (human)
brain morphogenesisSodium-dependent serotonin transporterHomo sapiens (human)
serotonin uptakeSodium-dependent serotonin transporterHomo sapiens (human)
membrane depolarizationSodium-dependent serotonin transporterHomo sapiens (human)
platelet aggregationSodium-dependent serotonin transporterHomo sapiens (human)
cellular response to retinoic acidSodium-dependent serotonin transporterHomo sapiens (human)
cellular response to cGMPSodium-dependent serotonin transporterHomo sapiens (human)
regulation of thalamus sizeSodium-dependent serotonin transporterHomo sapiens (human)
conditioned place preferenceSodium-dependent serotonin transporterHomo sapiens (human)
sodium ion transmembrane transportSodium-dependent serotonin transporterHomo sapiens (human)
amino acid transportSodium-dependent serotonin transporterHomo sapiens (human)
monoamine transportSodium-dependent dopamine transporter Homo sapiens (human)
neurotransmitter transportSodium-dependent dopamine transporter Homo sapiens (human)
lactationSodium-dependent dopamine transporter Homo sapiens (human)
sensory perception of smellSodium-dependent dopamine transporter Homo sapiens (human)
locomotory behaviorSodium-dependent dopamine transporter Homo sapiens (human)
response to xenobiotic stimulusSodium-dependent dopamine transporter Homo sapiens (human)
response to iron ionSodium-dependent dopamine transporter Homo sapiens (human)
dopamine transportSodium-dependent dopamine transporter Homo sapiens (human)
adenohypophysis developmentSodium-dependent dopamine transporter Homo sapiens (human)
response to nicotineSodium-dependent dopamine transporter Homo sapiens (human)
positive regulation of multicellular organism growthSodium-dependent dopamine transporter Homo sapiens (human)
regulation of dopamine metabolic processSodium-dependent dopamine transporter Homo sapiens (human)
response to cocaineSodium-dependent dopamine transporter Homo sapiens (human)
dopamine biosynthetic processSodium-dependent dopamine transporter Homo sapiens (human)
dopamine catabolic processSodium-dependent dopamine transporter Homo sapiens (human)
response to ethanolSodium-dependent dopamine transporter Homo sapiens (human)
cognitionSodium-dependent dopamine transporter Homo sapiens (human)
dopamine uptake involved in synaptic transmissionSodium-dependent dopamine transporter Homo sapiens (human)
response to cAMPSodium-dependent dopamine transporter Homo sapiens (human)
norepinephrine uptakeSodium-dependent dopamine transporter Homo sapiens (human)
prepulse inhibitionSodium-dependent dopamine transporter Homo sapiens (human)
dopamine uptakeSodium-dependent dopamine transporter Homo sapiens (human)
hyaloid vascular plexus regressionSodium-dependent dopamine transporter Homo sapiens (human)
amino acid transportSodium-dependent dopamine transporter Homo sapiens (human)
norepinephrine transportSodium-dependent dopamine transporter Homo sapiens (human)
sodium ion transmembrane transportSodium-dependent dopamine transporter Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (28)

Processvia Protein(s)Taxonomy
actin bindingSodium-dependent noradrenaline transporter Homo sapiens (human)
neurotransmitter transmembrane transporter activitySodium-dependent noradrenaline transporter Homo sapiens (human)
neurotransmitter:sodium symporter activitySodium-dependent noradrenaline transporter Homo sapiens (human)
dopamine:sodium symporter activitySodium-dependent noradrenaline transporter Homo sapiens (human)
norepinephrine:sodium symporter activitySodium-dependent noradrenaline transporter Homo sapiens (human)
protein bindingSodium-dependent noradrenaline transporter Homo sapiens (human)
monoamine transmembrane transporter activitySodium-dependent noradrenaline transporter Homo sapiens (human)
alpha-tubulin bindingSodium-dependent noradrenaline transporter Homo sapiens (human)
metal ion bindingSodium-dependent noradrenaline transporter Homo sapiens (human)
beta-tubulin bindingSodium-dependent noradrenaline transporter Homo sapiens (human)
integrin bindingSodium-dependent serotonin transporterHomo sapiens (human)
monoatomic cation channel activitySodium-dependent serotonin transporterHomo sapiens (human)
neurotransmitter transmembrane transporter activitySodium-dependent serotonin transporterHomo sapiens (human)
serotonin:sodium:chloride symporter activitySodium-dependent serotonin transporterHomo sapiens (human)
protein bindingSodium-dependent serotonin transporterHomo sapiens (human)
monoamine transmembrane transporter activitySodium-dependent serotonin transporterHomo sapiens (human)
antiporter activitySodium-dependent serotonin transporterHomo sapiens (human)
syntaxin-1 bindingSodium-dependent serotonin transporterHomo sapiens (human)
cocaine bindingSodium-dependent serotonin transporterHomo sapiens (human)
sodium ion bindingSodium-dependent serotonin transporterHomo sapiens (human)
identical protein bindingSodium-dependent serotonin transporterHomo sapiens (human)
nitric-oxide synthase bindingSodium-dependent serotonin transporterHomo sapiens (human)
actin filament bindingSodium-dependent serotonin transporterHomo sapiens (human)
serotonin bindingSodium-dependent serotonin transporterHomo sapiens (human)
protease bindingSodium-dependent dopamine transporter Homo sapiens (human)
signaling receptor bindingSodium-dependent dopamine transporter Homo sapiens (human)
neurotransmitter transmembrane transporter activitySodium-dependent dopamine transporter Homo sapiens (human)
dopamine:sodium symporter activitySodium-dependent dopamine transporter Homo sapiens (human)
protein bindingSodium-dependent dopamine transporter Homo sapiens (human)
monoamine transmembrane transporter activitySodium-dependent dopamine transporter Homo sapiens (human)
dopamine bindingSodium-dependent dopamine transporter Homo sapiens (human)
amine bindingSodium-dependent dopamine transporter Homo sapiens (human)
protein-containing complex bindingSodium-dependent dopamine transporter Homo sapiens (human)
metal ion bindingSodium-dependent dopamine transporter Homo sapiens (human)
protein phosphatase 2A bindingSodium-dependent dopamine transporter Homo sapiens (human)
heterocyclic compound bindingSodium-dependent dopamine transporter Homo sapiens (human)
norepinephrine:sodium symporter activitySodium-dependent dopamine transporter Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (19)

Processvia Protein(s)Taxonomy
plasma membraneSodium-dependent noradrenaline transporter Homo sapiens (human)
cell surfaceSodium-dependent noradrenaline transporter Homo sapiens (human)
membraneSodium-dependent noradrenaline transporter Homo sapiens (human)
neuronal cell body membraneSodium-dependent noradrenaline transporter Homo sapiens (human)
presynaptic membraneSodium-dependent noradrenaline transporter Homo sapiens (human)
plasma membraneSodium-dependent noradrenaline transporter Homo sapiens (human)
axonSodium-dependent noradrenaline transporter Homo sapiens (human)
plasma membraneSodium-dependent serotonin transporterHomo sapiens (human)
focal adhesionSodium-dependent serotonin transporterHomo sapiens (human)
endosome membraneSodium-dependent serotonin transporterHomo sapiens (human)
endomembrane systemSodium-dependent serotonin transporterHomo sapiens (human)
presynaptic membraneSodium-dependent serotonin transporterHomo sapiens (human)
membrane raftSodium-dependent serotonin transporterHomo sapiens (human)
synapseSodium-dependent serotonin transporterHomo sapiens (human)
postsynaptic membraneSodium-dependent serotonin transporterHomo sapiens (human)
serotonergic synapseSodium-dependent serotonin transporterHomo sapiens (human)
synapseSodium-dependent serotonin transporterHomo sapiens (human)
plasma membraneSodium-dependent serotonin transporterHomo sapiens (human)
neuron projectionSodium-dependent serotonin transporterHomo sapiens (human)
cytoplasmSodium-dependent dopamine transporter Homo sapiens (human)
plasma membraneSodium-dependent dopamine transporter Homo sapiens (human)
cell surfaceSodium-dependent dopamine transporter Homo sapiens (human)
membraneSodium-dependent dopamine transporter Homo sapiens (human)
axonSodium-dependent dopamine transporter Homo sapiens (human)
neuron projectionSodium-dependent dopamine transporter Homo sapiens (human)
neuronal cell bodySodium-dependent dopamine transporter Homo sapiens (human)
axon terminusSodium-dependent dopamine transporter Homo sapiens (human)
membrane raftSodium-dependent dopamine transporter Homo sapiens (human)
postsynaptic membraneSodium-dependent dopamine transporter Homo sapiens (human)
dopaminergic synapseSodium-dependent dopamine transporter Homo sapiens (human)
flotillin complexSodium-dependent dopamine transporter Homo sapiens (human)
axonSodium-dependent dopamine transporter Homo sapiens (human)
presynaptic membraneSodium-dependent dopamine transporter Homo sapiens (human)
plasma membraneSodium-dependent dopamine transporter Homo sapiens (human)
neuronal cell body membraneSodium-dependent dopamine transporter Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (10)

Assay IDTitleYearJournalArticle
AID261024Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cells2006Journal of medicinal chemistry, Feb-23, Volume: 49, Issue:4
1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors.
AID261025Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cells2006Journal of medicinal chemistry, Feb-23, Volume: 49, Issue:4
1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors.
AID261026Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cells2006Journal of medicinal chemistry, Feb-23, Volume: 49, Issue:4
1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors.
AID420092Inhibition of [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells by scintillation counting2009Bioorganic & medicinal chemistry, Jun-01, Volume: 17, Issue:11
A novel photoaffinity ligand for the dopamine transporter based on pyrovalerone.
AID261029Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cells2006Journal of medicinal chemistry, Feb-23, Volume: 49, Issue:4
1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors.
AID261027Inhibition of [3H] serotonin uptake into human SERT expressed in HEK293 cells2006Journal of medicinal chemistry, Feb-23, Volume: 49, Issue:4
1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors.
AID261028Displacement of [125I]RTI-55 from human NET expressed in HEK293 cells2006Journal of medicinal chemistry, Feb-23, Volume: 49, Issue:4
1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors.
AID420091Displacement of [3H]WIN-35428 from human dopamine transporter expressed in mouse N2A cells by scintillation counting2009Bioorganic & medicinal chemistry, Jun-01, Volume: 17, Issue:11
A novel photoaffinity ligand for the dopamine transporter based on pyrovalerone.
AID420093Ratio of IC50 for [3H]dopamine uptake at human dopamine transporter expressed in mouse N2A cells to Ki for displacement of [3H]WIN-35428 from human dopamine transporter expressed in mouse N2A cells2009Bioorganic & medicinal chemistry, Jun-01, Volume: 17, Issue:11
A novel photoaffinity ligand for the dopamine transporter based on pyrovalerone.
AID493017Wombat Data for BeliefDocking2006Journal of medicinal chemistry, Feb-23, Volume: 49, Issue:4
1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (22)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (9.09)18.7374
1990's2 (9.09)18.2507
2000's2 (9.09)29.6817
2010's16 (72.73)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (3.85%)5.53%
Reviews3 (11.54%)6.00%
Case Studies4 (15.38%)4.05%
Observational0 (0.00%)0.25%
Other18 (69.23%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
cocaine[no description available]medium40benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid		adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
1-phenyl-2-(1-pyrrolidinyl)-1-pentanone[no description available]medium30
naphyrone[no description available]medium10
bupropion[no description available]medium10aromatic ketone;
monochlorobenzenes;
secondary amino compound		antidepressant;
environmental contaminant;
xenobiotic
mazindol[no description available]medium20organic molecular entity
methylphenidate[no description available]medium20beta-amino acid ester;
methyl ester;
piperidines
lapatinib[no description available]medium11furans;
organochlorine compound;
organofluorine compound;
quinazolines		antineoplastic agent;
tyrosine kinase inhibitor
capecitabine[no description available]medium11carbamate ester;
cytidines;
organofluorine compound		antimetabolite;
antineoplastic agent;
prodrug
alpha-pyrrolidinopropiophenone[no description available]medium10aromatic ketone
cathinone[no description available]medium502-aminopropiophenone;
monoamine alkaloid		central nervous system stimulant;
psychotropic drug
betadex[no description available]medium10cyclodextrin
carboxymethyl-beta-cyclodextrin[no description available]medium10
methamphetamine[no description available]medium70amphetamines;
secondary amine		central nervous system stimulant;
environmental contaminant;
neurotoxin;
psychotropic drug;
xenobiotic
mephedrone[no description available]medium60amphetamines;
aromatic ketone;
secondary amino compound		environmental contaminant;
xenobiotic
phencyclidine[no description available]medium10benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
amphetamine[no description available]medium30primary amine
bromosuccinimide[no description available]medium10dicarboximide;
organobromine compound;
pyrrolidinone		reagent
diethylpropion[no description available]medium10aromatic ketone;
tertiary amine		appetite depressant
methylone[no description available]medium30benzodioxoles
monomethylpropion[no description available]medium20aromatic ketone;
secondary amino compound
jwh 018[no description available]medium10indolecarboxamide
catechol[no description available]medium10catecholsallelochemical;
genotoxin;
plant metabolite
guaiacol[no description available]medium10guaiacolsdisinfectant;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
expectorant;
plant metabolite
lidocaine[no description available]medium10benzenes;
monocarboxylic acid amide;
tertiary amino compound		anti-arrhythmia drug;
drug allergen;
environmental contaminant;
local anaesthetic;
xenobiotic
ethylmaleimide[no description available]medium10maleimidesanticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor
nomifensine[no description available]medium10isoquinolinesdopamine uptake inhibitor
1-(2-(diphenylmethoxy)ethyl)-4-(3-phenyl-2-propenyl)piperazine[no description available]medium10
phosphorus[no description available]medium10monoatomic phosphorus;
nonmetal atom;
pnictogen		macronutrient
reserpine[no description available]medium10alkaloid ester;
methyl ester;
yohimban alkaloid		adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic
oxoamide[no description available]low00aromatic ketone
4-oxo-4-(3-pyridyl)butanoic acid[no description available]low00aromatic ketone;
monocarboxylic acid;
pyridines
bw 306u[no description available]low00aromatic ketone
kynurenine[no description available]low00aromatic ketone;
non-proteinogenic alpha-amino acid;
substituted aniline		human metabolite
ro 48-8071[no description available]low00aromatic ether;
aromatic ketone;
bromobenzenes;
monofluorobenzenes;
olefinic compound;
tertiary amino compound		antineoplastic agent;
EC 5.4.99.7 (lanosterol synthase) inhibitor
amiodarone[no description available]low001-benzofurans;
aromatic ketone;
organoiodine compound;
tertiary amino compound		cardiovascular drug
anisindione[no description available]low00aromatic ketone;
beta-diketone		anticoagulant;
vitamin K antagonist
acetovanillone[no description available]low00acetophenones;
aromatic ketone;
methyl ketone		antirheumatic drug;
EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug;
plant metabolite
benzbromarone[no description available]low001-benzofurans;
aromatic ketone		uricosuric drug
bromperidol[no description available]low00aromatic ketone
buflomedil[no description available]low00aromatic ketone
celiprolol[no description available]low00aromatic ketone
droperidol[no description available]low00aromatic ketone;
benzimidazoles;
organofluorine compound		anaesthesia adjuvant;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic
dyclonine[no description available]low00aromatic ketone;
piperidines		topical anaesthetic
eperisone[no description available]low00aromatic ketone;
piperidines
eprazinone[no description available]low00aromatic ketone;
ether;
N-alkylpiperazine		mucolytic
ethacrynic acid[no description available]low00aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid		EC 2.5.1.18 (glutathione transferase) inhibitor;
ion transport inhibitor;
loop diuretic
haloperidol[no description available]low00aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
ketanserin[no description available]low00aromatic ketone;
organofluorine compound;
piperidines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
cardiovascular drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
ketorolac[no description available]low00amino acid;
aromatic ketone;
monocarboxylic acid;
pyrrolizines;
racemate		analgesic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
lofepramine[no description available]low00aromatic ketone;
dibenzoazepine;
monochlorobenzenes;
tertiary amino compound		antidepressant
mebendazole[no description available]low00aromatic ketone;
benzimidazoles;
carbamate ester		antinematodal drug;
microtubule-destabilising agent;
tubulin modulator
nocodazole[no description available]low00aromatic ketone;
benzimidazoles;
carbamate ester;
thiophenes		antimitotic;
antineoplastic agent;
microtubule-destabilising agent;
tubulin modulator
metyrapone[no description available]low00aromatic ketoneantimetabolite;
diagnostic agent;
EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor
moperone[no description available]low00aromatic ketone
phenindione[no description available]low00aromatic ketone;
beta-diketone		anticoagulant
pifithrin[no description available]low00aromatic ketone
pipamperone[no description available]low00aromatic ketone;
bipiperidines;
monocarboxylic acid amide;
organofluorine compound;
tertiary amino compound		dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
pirenperone[no description available]low00aromatic ketone
propafenone[no description available]low00aromatic ketone;
secondary alcohol;
secondary amino compound		anti-arrhythmia drug
propiomazine[no description available]low00aromatic ketone;
phenothiazines;
tertiary amino compound		dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
sedative;
serotonergic antagonist
raloxifene[no description available]low001-benzothiophenes;
aromatic ketone;
N-oxyethylpiperidine;
phenols		bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
spiperone[no description available]low00aromatic ketone;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound		alpha-adrenergic antagonist;
antipsychotic agent;
dopaminergic antagonist;
psychotropic drug;
serotonergic antagonist
suprofen[no description available]low00aromatic ketone;
monocarboxylic acid;
thiophenes		antirheumatic drug;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug
tiaprofenic acid[no description available]low00aromatic ketone;
monocarboxylic acid;
thiophenes		drug allergen;
non-steroidal anti-inflammatory drug
tolmetin[no description available]low00aromatic ketone;
monocarboxylic acid;
pyrroles		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
tolperisone[no description available]low00aromatic ketone
trifluperidol[no description available]low00aromatic ketone
zomepirac[no description available]low00aromatic ketone;
monocarboxylic acid;
monochlorobenzenes;
pyrroles		cardiovascular drug;
non-steroidal anti-inflammatory drug
acepromazine[no description available]low00aromatic ketone;
methyl ketone;
phenothiazines;
tertiary amino compound		phenothiazine antipsychotic drug
benziodarone[no description available]low00aromatic ketone
musk ketone[no description available]low00aromatic ketone
quinophthalone[no description available]low00aromatic ketone;
beta-diketone;
quinolines		dye
2-acetylthiophene[no description available]low00aromatic ketone
adrenalone[no description available]low00aromatic ketone
dibenzoylmethane[no description available]low00aromatic ketone;
beta-diketone		antimutagen;
antineoplastic agent;
metabolite
pyrazolanthrone[no description available]low00anthrapyrazole;
aromatic ketone;
cyclic ketone		antineoplastic agent;
c-Jun N-terminal kinase inhibitor;
geroprotector
benzil[no description available]low00alpha-diketone;
aromatic ketone
4'-(chloroacetyl)acetanilide[no description available]low00acetamides;
alpha-chloroketone;
aromatic ketone
3-acetylpyridine[no description available]low00aromatic ketone
ninhydrin[no description available]low00aromatic ketone;
beta-diketone;
indanones;
ketone hydrate		colour indicator;
human metabolite
capillin[no description available]low00aromatic ketone;
ynone
gallacetophenone[no description available]low00aromatic ketone
1-phenyl-1,2-propanedione[no description available]low00alpha-diketone;
aromatic ketone		plant metabolite
1,3-indandione[no description available]low00aromatic ketone;
beta-diketone;
indanones
phenacylamine[no description available]low00aromatic ketone
2-acetylpyrrole[no description available]low00aromatic ketone;
methyl ketone;
pyrroles
2-acetylpyridine[no description available]low00aromatic ketone
2-acetylfuran[no description available]low00aromatic ketone;
furans;
methyl ketone
sapropterin[no description available]low00aromatic ketone
fluanisone[no description available]low00aromatic ketone
3-Acetyl-2,4-dimethylpyrrole[no description available]low00aromatic ketone
metylperon[no description available]low00aromatic ketone
azaperone[no description available]low00aminopyridine;
aromatic ketone;
monofluorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
tertiary amino compound		antipsychotic agent;
dopaminergic antagonist
Propioveratrone[no description available]low00aromatic ketone
benperidol[no description available]low00aromatic ketone
2,4-diacetylphloroglucinol[no description available]low00aromatic ketone;
benzenetriol;
diketone;
methyl ketone		antifungal agent;
bacterial metabolite
4-benzoylpyridine[no description available]low00aromatic ketone
pyoluteorin[no description available]low00aromatic ketone;
beta-hydroxy ketone;
diol;
organochlorine compound;
organochlorine pesticide;
polyketide;
pyrroles;
resorcinols		antibacterial agent;
antifungal agent;
apoptosis inducer;
bacterial metabolite;
marine metabolite
flubendazole[no description available]low00aromatic ketone;
benzimidazoles;
carbamate ester;
organofluorine compound		antinematodal drug;
teratogenic agent
4-ipomeanol[no description available]low00aromatic ketone
ticrynafen[no description available]low00aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid;
thiophenes		antihypertensive agent;
hepatotoxic agent;
loop diuretic
celiprolol hydrochloride[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-(1-imidazolyl)ethanone[no description available]low00aromatic ketone
enoximone[no description available]low00aromatic ketone
bupropion hydrochloride[no description available]low00aromatic ketone
3-oxo-3-phenylpropanenitrile[no description available]low00aromatic ketone;
beta-ketonitrile
fenofibric acid[no description available]low00aromatic ketone;
chlorobenzophenone;
monocarboxylic acid		drug metabolite;
marine xenobiotic metabolite
inaperisone[no description available]low00aromatic ketone
valerophenone[no description available]low00aromatic ketoneplant metabolite;
volatile oil component
2,4,6-trihydroxyacetophenone[no description available]low00aromatic ketone;
benzenetriol;
methyl ketone		MALDI matrix material;
plant metabolite
perilla ketone[no description available]low00aromatic ketone
butofilolol[no description available]low00aromatic ketone
2,6-dihydroxyacetophenone[no description available]low00aromatic ketone
2',4'-Dimethoxypropiophenone[no description available]low00aromatic ketone
propipocaine[no description available]low00aromatic ketone
hp 873[no description available]low001,2-benzoxazoles;
aromatic ether;
aromatic ketone;
methyl ketone;
monoamine;
organofluorine compound;
piperidines;
tertiary amino compound		dopaminergic antagonist;
second generation antipsychotic;
serotonergic antagonist
prifelone[no description available]low00aromatic ketone
metamfepramone[no description available]low00aromatic ketone
1-(2,4-dihydroxyphenyl)-1-hexanone[no description available]low00aromatic ketone
1-(2,4-Dihydroxyphenyl)-1-butanone[no description available]low00aromatic ketone
isoxaflutole[no description available]low00(trifluoromethyl)benzenes;
aromatic ketone;
cyclopropanes;
isoxazoles;
sulfone		agrochemical;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
proherbicide
sulcotrione[no description available]low00aromatic ketone;
beta-triketone;
cyclohexanones;
sulfone		carotenoid biosynthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic
tolperisone hydrochloride[no description available]low00aromatic ketone
beta-(4-fluorobenzoyl)propionic acid[no description available]low00aromatic ketone
lobeline[no description available]low00aromatic ketone;
piperidine alkaloid;
tertiary amine		nicotinic acetylcholine receptor agonist
aflatoxin q1[no description available]low00aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human xenobiotic metabolite
desethylamiodarone[no description available]low00aromatic ketone
ly 117018[no description available]low001-benzothiophenes;
aromatic ketone;
N-alkylpyrrolidine;
phenols		bone density conservation agent;
estrogen receptor antagonist;
estrogen receptor modulator
fpl 55712[no description available]low00aromatic ketone
(6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide[no description available]low00aromatic ketone
4-hydoxy-1-(3-pyridyl)-1-butanone[no description available]low00aromatic ketone
1-[4-[2-hydroxy-3-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]propoxy]phenyl]-1-propanone[no description available]low00aromatic ketone
3-(1-piperidinyl)-1-(4-propan-2-yloxyphenyl)-1-propanone[no description available]low00aromatic ketone
3-n-methylspiperone[no description available]low00aromatic ketone
ly 255283[no description available]low00aromatic ketone
eperisone[no description available]low00aromatic ketone
n-(4-aminophenethyl)spiroperidol[no description available]low00aromatic ketone
esonarimod[no description available]low00aromatic ketone
oxoline[no description available]low00aromatic ketone;
tetralins		geroprotector
n-acetyl-n-formyl-5-methoxykynurenamine[no description available]low00aromatic ketone
4(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridine[no description available]low00aromatic ketone
mesotrione[no description available]low00aromatic ketone;
beta-triketone;
C-nitro compound;
sulfone		carotenoid biosynthesis inhibitor;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
environmental contaminant;
herbicide;
xenobiotic
rs 67333[no description available]low00aromatic ketone
aflatoxin b1[no description available]low00aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human metabolite
dronedarone[no description available]low001-benzofurans;
aromatic ether;
aromatic ketone;
sulfonamide;
tertiary amino compound		anti-arrhythmia drug;
environmental contaminant;
xenobiotic
(1-tert-butyl-5-phenyl-3-pyrrolyl)-phenylmethanone[no description available]low00aromatic ketone
veratrone[no description available]low00aromatic ketone;
dimethoxybenzene;
primary alcohol
7-benzoyl-3-chloroindolizine-1,2-dicarboxylic acid dimethyl ester[no description available]low00aromatic ketone
bromodeoxytopsentin[no description available]low00aromatic ketone;
bromoindole;
imidazoles;
indole alkaloid		antibacterial agent;
EC 2.7.1.40 (pyruvate kinase) inhibitor;
marine metabolite
amiodarone hydrochloride[no description available]low00aromatic ketone
knipholone[no description available]low00aromatic ketone;
dihydroxyanthraquinone;
methoxybenzenes;
methyl ketone;
polyphenol;
resorcinols		antineoplastic agent;
antioxidant;
antiplasmodial drug;
leukotriene antagonist;
metabolite
alpha bitter acid[no description available]low00aromatic ketone;
cyclic ketone;
diketone;
tertiary alpha-hydroxy ketone;
triol		antibacterial drug;
antioxidant;
cyclooxygenase 2 inhibitor;
metabolite
2-Acetylthiazole[no description available]low00aromatic ketone
1-[3-acetyl-5-[(4-bromophenyl)-oxomethyl]-1,3,7-triazabicyclo[3.3.1]nonan-7-yl]ethanone[no description available]low00aromatic ketone
LSM-42773[no description available]low00aromatic ketone
1-(4-methylphenyl)-2-(1H-1,2,4-triazol-5-ylthio)ethanone[no description available]low00aromatic ketone
3-(4-fluoroanilino)-1-(3-nitrophenyl)-1-propanone[no description available]low00aromatic ketone
(5-methoxy-3-benzofuranyl)-phenylmethanone[no description available]low00aromatic ketone
3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone[no description available]low00aromatic ketone
(2-amino-5-methyl-3-thiophenyl)-thiophen-2-ylmethanone[no description available]low00aromatic ketone;
thiophenes
1-(2,5-dimethoxyphenyl)-2-[[5-(2-furanyl)-4-propyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(1,3-benzodioxol-5-ylmethyl)-3-hydroxy-3-[2-(4-methylphenyl)-2-oxoethyl]-2-indolone[no description available]low00aromatic ketone
2-[(5-amino-1-phenacyl-1,2,4-triazol-3-yl)thio]-N-(3-cyano-4,5-dimethyl-2-thiophenyl)acetamide[no description available]low00aromatic ketone
2-[[1-(2-methoxyethyl)-5-tetrazolyl]thio]-1-phenylethanone[no description available]low00aromatic ketone
1-(4-methoxyphenyl)-2-(5-thiophen-2-yl-2-tetrazolyl)ethanone[no description available]low00aromatic ketone
1-(3-methoxyphenyl)-2-[[4-methyl-5-[[(4-phenyl-2-thiazolyl)amino]methyl]-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(5-chloro-2-methoxyphenyl)-2-[(4,6-diamino-2-pyrimidinyl)thio]ethanone[no description available]low00aromatic ketone
2-[(5-methyl-1H-1,2,4-triazol-3-yl)thio]-1-phenylethanone[no description available]low00aromatic ketone
1-(4-chlorophenyl)-2-[[4-ethyl-5-(2-methyl-3-furanyl)-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(3,4-dichlorophenyl)-2-[[4-(2-furanylmethyl)-5-(3-pyridinyl)-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
(4-chloro-5-hydroxy-3-benzofuranyl)-phenylmethanone[no description available]low00aromatic ketone
3-(3-benzoyl-6-chloro-4,5-dihydroxy-7-benzofuranyl)pentane-2,4-dione[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(2-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(4-fluorophenyl)-2-[[4-(2-furanylmethyl)-5-(phenoxymethyl)-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
N-(4-acetylphenyl)-2-thiophen-2-ylacetamide[no description available]low00aromatic ketone
4-thiomorpholinecarbodithioic acid [2-(4-chlorophenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
1-[4-[(2-methyl-4-quinolinyl)amino]phenyl]ethanone[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[(4,6-dimethyl-2-pyrimidinyl)thio]ethanone[no description available]low00aromatic ketone
1-(4-Chlorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)thio]ethan-1-one[no description available]low00aromatic ketone
4-(4-ethoxyphenyl)-4-oxobutanoic acid[no description available]low00aromatic ketone
4-bromo-N-phenacylbenzamide[no description available]low00aromatic ketone
N1-[2-(4-chlorophenyl)-2-oxoethyl]-4-chlorobenzamide[no description available]low00aromatic ketone
1-[4-[(4,6-dimethyl-2-pyrimidinyl)amino]phenyl]ethanone[no description available]low00aromatic ketone
4-amino-2-(phenacylthio)-5-pyrimidinecarboxylic acid ethyl ester[no description available]low00aromatic ketone
(3-hydroxy-5,6,7,8-tetrahydro-4H-cyclohepta[d]imidazol-2-yl)-phenylmethanone[no description available]low00aromatic ketone
2-fluoro-N-phenacylbenzamide[no description available]low00aromatic ketone
2-(Benzotriazol-1-yl)-1-(4-bromophenyl)ethanone[no description available]low00aromatic ketoneanticoronaviral agent
2-(4-methylanilino)-1-(4-nitrophenyl)ethanone[no description available]low00aromatic ketone
1-(3-((2',4'-Dimethyl-[4,5'-bithiazol]-2-yl)amino)phenyl)ethanone[no description available]low00aromatic ketone
1-[4-(1-azepanyl)-3-fluorophenyl]-1-propanone[no description available]low00aromatic ketone
2-(8-quinolinylthio)acetic acid phenacyl ester[no description available]low00aromatic ketone
2-(4-ethoxyanilino)-1-(4-methylphenyl)ethanone[no description available]low00aromatic ketone
1-[4-[[6-methyl-2-(methylthio)-5-prop-2-enyl-4-pyrimidinyl]amino]phenyl]ethanone[no description available]low00aromatic ketone
(4-methoxyphenyl)-(3-methyl-2-propyl-4-imidazolyl)methanone[no description available]low00aromatic ketone
5-[(5-acetyl-2-propan-2-yloxyphenyl)methyl]-6-hydroxy-2-sulfanylidene-1H-pyrimidin-4-one[no description available]low00aromatic ketone
N-(5-benzoyl-4-phenyl-2-thiazolyl)carbamic acid methyl ester[no description available]low00aromatic ketone
2-chloro-N-[5-ethyl-3-[(4-methylphenyl)-oxomethyl]-2-thiophenyl]acetamide[no description available]low00aromatic ketone
1-(4-fluorophenyl)-2-(2-pyridinylthio)ethanone[no description available]low00aromatic ketone
N-(3-acetylphenyl)-2-thiophen-2-ylacetamide[no description available]low00aromatic ketone
3-(4-bromoanilino)-1-(3-nitrophenyl)-1-propanone[no description available]low00aromatic ketone
3-anilino-1-(3-nitrophenyl)-1-propanone[no description available]low00aromatic ketone
1-(5-ethyl-2,4-dihydroxyphenyl)-2-(2-fluorophenoxy)ethanone[no description available]low00aromatic ketone
3-[1-(4-acetylphenyl)-5-thiophen-2-yl-2-pyrrolyl]propanoic acid[no description available]low00aromatic ketone
(7-methoxy-2-benzofuranyl)-(4-nitrophenyl)methanone[no description available]low00aromatic ketone
4-[2-(3-methoxyphenyl)-2-oxoethoxy]benzoic acid methyl ester[no description available]low00aromatic ketone
4-phenacyloxybenzoic acid methyl ester[no description available]low00aromatic ketone
1-(2-hydroxyphenyl)-2-(2H-tetrazol-5-yl)ethanone[no description available]low00aromatic ketone
2-(methylamino)benzoic acid [2-(4-fluorophenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-[(4-methyl-2-pyrimidinyl)thio]-1-(3-nitrophenyl)ethanone[no description available]low00aromatic ketone
3-[[(3-acetylanilino)-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester[no description available]low00aromatic ketone
1-(3-acetylphenyl)-3-(2-pyridinylmethyl)urea[no description available]low00aromatic ketone
1-(4-acetylphenyl)-3-[2-(4-fluorophenyl)ethyl]thiourea[no description available]low00aromatic ketone
1-phenyl-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)ethanone[no description available]low00aromatic ketone
3-tert-butyl-7-[[2-(4-methylphenyl)-2-oxoethyl]thio]-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one[no description available]low00aromatic ketone
LSM-4563[no description available]low00aromatic ketone
1-[4-[3-[5-(2-furanyl)-1H-pyrazol-3-yl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]phenyl]ethanone[no description available]low00aromatic ketone
1,3-diphenyl-4-pyrazolecarboxylic acid [2-(4-methyl-3-nitrophenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
Silica aerogel[no description available]low00aromatic ketone
2-[[5-(1-benzotriazolylmethyl)-4-methyl-1,2,4-triazol-3-yl]thio]-1-(2-fluorophenyl)ethanone[no description available]low00aromatic ketone
N-(4-acetylphenyl)-2-[[1-(3,5-dimethoxyphenyl)-5-tetrazolyl]thio]acetamide[no description available]low00aromatic ketone
3,4-dimethoxybenzoic acid [2-(3,4-dimethoxyphenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-[2-[2-(4-chlorophenyl)-2-oxoethoxy]phenyl]isoindole-1,3-dione[no description available]low00aromatic ketone
2-[[5-(7-methoxy-2-benzofuranyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-1-(4-methoxyphenyl)ethanone[no description available]low00aromatic ketone
2-[[4,6-bis(1-piperidinyl)-1,3,5-triazin-2-yl]thio]-1-phenylethanone[no description available]low00aromatic ketone
1-(2,5-dimethylphenyl)-2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]ethanone[no description available]low00aromatic ketone
3-methyl-1,5-dithiophen-2-ylpentane-1,5-dione[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(4-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
2-[[5-(3-chlorophenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanone[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(3-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(4-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(3-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
(4-chlorophenyl)-(5-hydroxy-2-methyl-4,6-dinitro-3-benzofuranyl)methanone[no description available]low00aromatic ketone
1-(3,4-dimethylphenyl)-2-[[5-[[2-(4-ethoxyanilino)-4-thiazolyl]methyl]-1,3,4-oxadiazol-2-yl]thio]ethanone[no description available]low00aromatic ketone
1-(4-fluorophenyl)-2-[(2-propyl-4-quinazolinyl)thio]ethanone[no description available]low00aromatic ketone
(5-chloro-2-hydroxyphenyl)-[2-ethyl-3-(4-fluorophenyl)-6-pyrazolo[1,5-a]pyrimidinyl]methanone[no description available]low00aromatic ketone
N,N-dimethylcarbamothioic acid O-[4-[2-[(4-chlorophenyl)thio]-1-oxoethyl]-2,6-dimethylphenyl] ester[no description available]low00aromatic ketone
4-[(4-tert-butylphenyl)-oxomethyl]-N-[2-(2-pyridinyl)ethyl]-1H-pyrrole-2-carboxamide[no description available]low00aromatic ketone
(4-chlorophenyl)-[5-(4-morpholinyl)-4-(2-pyridinyl)-2-thiophenyl]methanone[no description available]low00aromatic ketone
N,N-dimethylcarbamic acid [4-[2-(benzenesulfonyl)-1-oxoethyl]-2,6-dimethylphenyl] ester[no description available]low00aromatic ketone
N,N-dimethylcarbamic acid [4-[2-(4-fluorophenyl)sulfonyl-1-oxoethyl]-2,6-dimethylphenyl] ester[no description available]low00aromatic ketone
2-chloro-1-[1-(2-furanylmethyl)-2,5-dimethyl-3-pyrrolyl]ethanone[no description available]low00aromatic ketone
N-[(phenacylamino)-sulfanylidenemethyl]-2-furancarboxamide[no description available]low00aromatic ketone
3-phenylpropionylglycine[no description available]low00aromatic ketone
4-amino-5-[(4-methylphenyl)-oxomethyl]-2-(prop-2-enylamino)-3-thiophenecarbonitrile[no description available]low00aromatic ketone
2-amino-4-[[2-(4-bromophenyl)-2-oxoethyl]thio]-3-azaspiro[5.5]undeca-1,4-diene-1,5-dicarbonitrile[no description available]low00aromatic ketone
2-[[4-ethyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]-1-(4-methylphenyl)ethanone[no description available]low00aromatic ketone
7-amino-9-(phenacylthio)-8-azaspiro[4.5]deca-6,9-diene-6,10-dicarbonitrile[no description available]low00aromatic ketone
6-(bromomethyl)-1,3-dimethyl-5-[(4-nitrophenyl)-oxomethyl]pyrimidine-2,4-dione[no description available]low00aromatic ketone
1-(2,4-dimethylphenyl)-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)ethanone[no description available]low00aromatic ketone
4-(4-acetylphenoxy)butanoic acid [5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]methyl ester[no description available]low00aromatic ketone
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-ethyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanone[no description available]low00aromatic ketone
2-chloro-1-[2,5-dimethyl-1-(5-methyl-3-isoxazolyl)-3-pyrrolyl]ethanone[no description available]low00aromatic ketone
2-[2-[[5-cyano-1-(3-methoxypropyl)-6-oxo-3-pyridinyl]-oxomethyl]-4-methoxyphenoxy]-N-(5-methyl-3-isoxazolyl)acetamide[no description available]low00aromatic ketone
1-[2-[2,5-dimethyl-1-(phenylmethyl)-3-pyrrolyl]-2-oxoethyl]pyrrolidine-2,5-dione[no description available]low00aromatic ketone
3,5-dimethyl-4-isoxazolecarboxylic acid [2-(4-amino-1-methyl-2,6-dioxo-3-propyl-5-pyrimidinyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-[3-[(4-chlorophenyl)-oxomethyl]-6-methoxy-4-oxo-1-quinolinyl]-N-(4-fluorophenyl)acetamide[no description available]low00aromatic ketone;
quinolines
1-[4-[(2-amino-5-thiazolyl)methyl]phenyl]ethanone[no description available]low00aromatic ketone
[9-(4-ethoxyphenyl)sulfonyl-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanone[no description available]low00aromatic ketone;
quinolines
4-chloro-N-[(phenacylamino)-sulfanylidenemethyl]benzamide[no description available]low00aromatic ketone
N-[(phenacylamino)-sulfanylidenemethyl]cyclohexanecarboxamide[no description available]low00aromatic ketone
4-(4-chlorophenyl)-4-oxobutanoic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester[no description available]low00aromatic ketone
1-(2-chlorophenyl)-2-(3,5-dimethyl-4-nitro-1-pyrazolyl)ethanone[no description available]low00aromatic ketone
[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-[4-(1-piperidinylsulfonyl)phenyl]methanone[no description available]low00aromatic ketone
4-(dimethylamino)benzoic acid [2-(2-methoxyphenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-chloro-3-pyridinecarboxylic acid [2-(4-fluorophenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
3-(1,3-benzothiazol-2-yl)propanoic acid phenacyl ester[no description available]low00aromatic ketone
5-[(2-hydroxy-5-methylphenyl)-oxomethyl]-N,1-bis[2-(4-methoxyphenyl)ethyl]-2-oxo-3-pyridinecarboxamide[no description available]low00aromatic ketone
2-[(1-oxido-2-pyridin-1-iumyl)thio]-1-(4-phenylphenyl)ethanone[no description available]low00aromatic ketone
2-(1H-benzimidazol-2-yl)-1-(3-nitrophenyl)ethanone[no description available]low00aromatic ketone
2-[[2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl]thio]-3-pyridinecarboxylic acid[no description available]low00aromatic ketone
2-[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]-1-(2-methoxyphenyl)ethanone[no description available]low00aromatic ketone
2-chloro-1-[1-[2-(4-chlorophenyl)ethyl]-2,5-dimethyl-3-pyrrolyl]ethanone[no description available]low00aromatic ketone
2-chloro-3-pyridinecarboxylic acid [2-(4-ethylphenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
3-(4-acetylphenyl)-1-(phenylmethyl)-1-propylthiourea[no description available]low00aromatic ketone
2-anilinobenzoic acid [2-(4-acetylanilino)-2-oxoethyl] ester[no description available]low00aromatic ketone
N-(2-acetylphenyl)-2-(2-oxo-1-quinoxalinyl)acetamide[no description available]low00aromatic ketone
2-[[5-(5-bromo-2-furanyl)-4-(phenylmethyl)-1,2,4-triazol-3-yl]thio]-1-(2-fluorophenyl)ethanone[no description available]low00aromatic ketone
4,5-dichloro-2-[2-[2,5-dimethyl-1-(2,2,2-trifluoroethyl)-3-pyrrolyl]-2-oxoethyl]-3-pyridazinone[no description available]low00aromatic ketone
7-[(4-acetylphenoxy)methyl]-5-thiazolo[3,2-a]pyrimidinone[no description available]low00aromatic ketone
(3-amino-4,6-dimethyl-2-thieno[2,3-b]pyridinyl)-(2-chlorophenyl)methanone[no description available]low00aromatic ketone
1-[4-[(2-bromophenyl)-oxomethyl]-1H-pyrrol-2-yl]-2,2,2-trichloroethanone[no description available]low00aromatic ketone
2-(4-hydroxy-1,3-thiazol-2-yl)-1-phenylethan-1-one[no description available]low00aromatic ketone
N-[1-(4-methyl-6-oxo-1-pyrimidinyl)-2-oxo-2-phenylethyl]benzamide[no description available]low00aromatic ketone
N-[5-ethyl-3-[(4-methoxyphenyl)-oxomethyl]-2-thiophenyl]-2-(4-methyl-1-piperazinyl)acetamide[no description available]low00aromatic ketone
4-[[5-ethyl-3-[(4-methoxyphenyl)-oxomethyl]-2-thiophenyl]amino]-4-oxobutanoic acid[no description available]low00aromatic ketone
(2-anilino-4-methyl-1,3-thiazol-5-yl)(4-methoxyphenyl)methanone[no description available]low00aromatic ketone
(4-chlorophenyl)-[6,7-dichloro-4-[(dimethylamino)methyl]-5-hydroxy-2-methyl-3-benzofuranyl]methanone[no description available]low00aromatic ketone
cid 2858522[no description available]low00aromatic ketone
1-(3-nitrophenyl)-2-(1H-1,2,4-triazol-5-ylthio)ethanone[no description available]low00aromatic ketone
2-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]-1-phenylethanone[no description available]low00aromatic ketone
(3-amino-5-nitro-2-benzofuranyl)-phenylmethanone[no description available]low00aromatic ketone
2-nitrobenzoic acid [1-(4-methylphenyl)-1-oxopropan-2-yl] ester[no description available]low00aromatic ketone
3-hydroxy-3-[2-oxo-2-[4-(1-pyrrolyl)phenyl]ethyl]-1H-indol-2-one[no description available]low00aromatic ketone
1-[4-[3-[4-(4-fluorophenyl)-1-piperazinyl]-2-hydroxypropoxy]phenyl]-1-propanone[no description available]low00aromatic ketone
1-[4-[4-[[6-bromo-2-(3-pyridinyl)-4-quinolinyl]-oxomethyl]-1-piperazinyl]phenyl]ethanone[no description available]low00aromatic ketone
N-[4-[(3-acetylphenyl)sulfamoyl]phenyl]-1-piperidinecarboxamide[no description available]low00aromatic ketone
(2,5-dimethylphenyl)-(6-methyl-5-imidazo[2,1-b]thiazolyl)methanone[no description available]low00aromatic ketone
3-hydroxy-1-adamantanecarboxylic acid [2-[1-(2-methoxyethyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] ester[no description available]low00aromatic ketone
[2-[(2,6-dimethyl-4-morpholinyl)-oxomethyl]phenyl]-(1H-imidazol-2-yl)methanone[no description available]low00aromatic ketone
3-(2-furanyl)-3-oxo-2-(2-pyridinyl)propanenitrile[no description available]low00aromatic ketone
1-[4-ethoxy-3-[[[4-(2-oxolanylmethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]thio]methyl]phenyl]ethanone[no description available]low00aromatic ketone
timiperone[no description available]low00aromatic ketone
adefovir[no description available]low00aromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
organooxygen heterocyclic antibiotic;
polyphenol		antimalarial;
Aspergillus metabolite;
marine metabolite
phenyl-(2-thiophen-2-yl-5,10b-dihydro-1H-pyrazolo[1,5-c][1,3]benzoxazin-5-yl)methanone[no description available]low00aromatic ketone
N-[3-[(4-chlorophenyl)-oxomethyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-3-pyridinecarboxamide[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[(4-methyl-1,2,4-triazol-3-yl)thio]ethanone[no description available]low00aromatic ketone
2-quinolinecarboxylic acid (1-oxo-1-phenylpropan-2-yl) ester[no description available]low00aromatic ketone
N-(3-acetylphenyl)-3-(1-ethyl-3-methyl-4-pyrazolyl)-4,5-dihydroisoxazole-5-carboxamide[no description available]low00aromatic ketone
1-[4-[4-[[1-(4-chlorophenyl)sulfonylcyclopropyl]-oxomethyl]-1-piperazinyl]phenyl]ethanone[no description available]low00aromatic ketone
1-[2-(4-bromophenyl)-2-oxoethyl]-3-(2-furanylmethyl)-6,7-dimethoxyquinazoline-2,4-dione[no description available]low00aromatic ketone
N-(3-acetylphenyl)-3,5-dimethyl-4-isoxazolesulfonamide[no description available]low00aromatic ketone
3-[4-[2-(3,4-dimethoxyphenyl)-2-oxoethyl]-3-oxo-[1,2,4]triazino[2,3-a]benzimidazol-2-yl]propanoic acid[no description available]low00aromatic ketone
3-[(3-fluorophenyl)methyl]-8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one[no description available]low00aromatic ketone
4-[(4-acetyl-2-methoxyphenyl)methoxy]-3-methoxybenzoic acid [1-(carbamoylamino)-1-oxopropan-2-yl] ester[no description available]low00aromatic ketone
N-(2-chloro-3-pyridinyl)-3-oxo-3-phenylpropanamide[no description available]low00aromatic ketone
5-[2-(4-bromophenyl)-2-oxoethyl]-1,3-diphenyl-2-sulfanylidene-4-imidazolidinone[no description available]low00aromatic ketone
2-(thiophen-2-ylsulfonylamino)benzoic acid [2-(3-acetylanilino)-2-oxo-1-phenylethyl] ester[no description available]low00aromatic ketone
4-(4-chlorophenyl)-N-[3-[(4-methoxyphenyl)sulfamoyl]phenyl]-4-oxobutanamide[no description available]low00aromatic ketone
2-[4-[oxo(thiophen-2-yl)methyl]phenyl]propanoic acid methyl ester[no description available]low00aromatic ketone
N-[3-[(3-chlorophenyl)sulfamoyl]-4-methylphenyl]-3-(4-nitrophenyl)-3-oxopropanamide[no description available]low00aromatic ketone
rs 102221[no description available]low00aromatic ketone
N-[2-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-4-oxo-3-quinazolinyl]benzamide[no description available]low00aromatic ketone
3-methyl-2-methylene-1,5-diphenylpentane-1,5-dione[no description available]low00aromatic ketone
2-[1-(2-methylphenyl)-3-oxo-3-thiophen-2-ylpropyl]propanedinitrile[no description available]low00aromatic ketone
(4-chlorophenyl)-(7-methyl-3-imidazo[1,2-a]pyridinyl)methanone[no description available]low00aromatic ketone
2-[(4-hydroxy-3-nitrophenyl)sulfonylamino]benzoic acid [2-(4-methoxyphenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
4-benzoyl-2-heptyl-5-methyl-4H-pyrazol-3-one[no description available]low00aromatic ketone
(4-benzoyl-1-methyl-3-pyrrolidinyl)-phenylmethanone[no description available]low00aromatic ketone
6-benzoyl-2-phenyl-5-(trifluoromethyl)-3-pyridazinone[no description available]low00aromatic ketone
LY-310762[no description available]low00aromatic ketone;
monofluorobenzenes;
oxindoles;
piperidines;
tertiary amino compound		receptor modulator;
serotonergic antagonist
1-(4-methylphenyl)-2-[(1-phenyl-2-imidazolyl)thio]ethanone[no description available]low00aromatic ketone
gr 103691[no description available]low00aromatic ketone
4-(1,3-dioxo-2-benzo[de]isoquinolinyl)butanoic acid [2-(2-acetylanilino)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-chloro-N-(2,6-dimethylphenyl)-3-oxo-3-phenylpropanamide[no description available]low00aromatic ketone
1-(4-chlorophenyl)-2-[[3-(3-methylphenyl)-1,2,4-thiadiazol-5-yl]thio]ethanone[no description available]low00aromatic ketone
N-(3-acetylphenyl)-2-[[6-chloro-3-(2-hydroxypropyl)-4-methyl-2-oxo-1-benzopyran-7-yl]oxy]acetamide[no description available]low00aromatic ketone
4-[4-(4-acetylphenyl)-1-piperazinyl]-N-[3-(dimethylamino)propyl]-3-nitrobenzenesulfonamide[no description available]low00aromatic ketone
2-chloro-1-[1-(3-isoxazolyl)-2,5-dimethyl-3-pyrrolyl]ethanone[no description available]low00aromatic ketone
5-[(5-bromo-2-hydroxyphenyl)-oxomethyl]-1-cyclohexyl-2-oxo-3-pyridinecarbonitrile[no description available]low00aromatic ketone
2-[(5-ethyl-2-thiophenyl)-oxomethyl]benzoic acid[no description available]low00aromatic ketone
3-[4-(4-morpholinylsulfonyl)phenyl]propanoic acid [2-(4-acetylanilino)-2-oxoethyl] ester[no description available]low00aromatic ketone
rottlerin[no description available]low00aromatic ketone;
benzenetriol;
chromenol;
enone;
methyl ketone		anti-allergic agent;
antihypertensive agent;
antineoplastic agent;
apoptosis inducer;
K-ATP channel agonist;
metabolite
isoegomaketone[no description available]low00aromatic ketone
palbociclib[no description available]low00aminopyridine;
aromatic ketone;
cyclopentanes;
piperidines;
pyridopyrimidine;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
radicinin[no description available]low00aromatic ketone
oxyfedrine[no description available]low00aromatic ketone
3-(dimethylamino)-1-(5-methyl-3-phenyl-4-isoxazolyl)-2-propen-1-one[no description available]low00aromatic ketone
2-[[5,6-bis(2-furanyl)-1,2,4-triazin-3-yl]thio]-1-(4-methoxyphenyl)ethanone[no description available]low00aromatic ketone
buflomedil hydrochloride[no description available]low00aromatic ketone
ciproxifan[no description available]low00aromatic ketone
4'-methyl-alpha-pyrrolidinopropiophenone[no description available]low00aromatic ketone
l-165041[no description available]low00aromatic ketone
N-(4-acetylphenyl)-2-[[3-(2-pyridinyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]thio]acetamide[no description available]low00aromatic ketone
N-[4-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]phenyl]acetamide[no description available]low00aromatic ketone
6-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]-3,4-dihydro-1H-quinolin-2-one[no description available]low00aromatic ketone
2-(2-benzoyl-1-pyrrolyl)-N-methyl-N-(phenylmethyl)acetamide[no description available]low00aromatic ketone
ic 86621[no description available]low00aromatic ketone
scio-469[no description available]low00aromatic amide;
aromatic ketone;
chloroindole;
dicarboxylic acid diamide;
indolecarboxamide;
monofluorobenzenes;
N-acylpiperazine;
N-alkylpiperazine		antineoplastic agent;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
am 694[no description available]low00aromatic ketone;
indoles;
organofluorine compound;
organoiodine compound;
synthetic cannabinoid		cannabinoid receptor agonist
fonsecinone a[no description available]low00aromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
polyphenol		antibacterial agent;
Aspergillus metabolite
e 5555[no description available]low00aromatic ketone
cytosporone b[no description available]low00aromatic ketone
benzobicyclon[no description available]low00aromatic ketone;
carbobicyclic compound;
cyclic ketone;
monochlorobenzenes;
organic sulfide;
sulfone
tembotrione[no description available]low00aromatic ketone;
beta-triketone;
cyclic ketone;
ether;
monochlorobenzenes;
organofluorine compound;
sulfone		agrochemical;
carotenoid biosynthesis inhibitor;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
herbicide
y134 compound[no description available]low00aromatic ketone
N-[2-(3,4-dimethoxyphenyl)ethyl]-4-(4-ethoxyphenyl)-2,4-dioxobutanamide[no description available]low00aromatic ketone
[9-(benzenesulfonyl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanone[no description available]low00aromatic ketone;
quinolines
alpha(-(cyclopropylcarbonyl)-2-(methyvlsulfonyl)-beta-oxo-4-(trifluromethyl)benzenepropanenitrile)[no description available]low00(trifluoromethyl)benzenes;
aromatic ketone;
beta-diketone;
cyclopropanes;
nitrile;
sulfone		agrochemical;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
herbicide
aflatoxin m1[no description available]low00aflatoxin;
aromatic ether;
aromatic ketone;
tertiary alcohol		Aspergillus metabolite;
human xenobiotic metabolite;
mammalian metabolite
acetic acid [4-[[(3aS,4R,9aS,9bR)-2-(2-naphthalenyl)-1,3-dioxo-3a,4,9a,9b-tetrahydropyrrolo[1,2]pyrrolo[3,5-b]pyridazin-4-yl]-oxomethyl]phenyl] ester[no description available]low00aromatic ketone
(3R,3aR,7aR)-3-[4-(4-acetylphenyl)-2-fluorophenyl]-7a-methyl-2-(phenylmethyl)-3,3a,6,7-tetrahydroisoindol-1-one[no description available]low00aromatic ketone
(3-propan-2-yloxyphenyl)-[1-[(1-propan-2-yl-4-pyrazolyl)methyl]-3-piperidinyl]methanone[no description available]low00aromatic ketone
[2-(methylthio)phenyl]-[1-[oxo(4-thiadiazolyl)methyl]-3-piperidinyl]methanone[no description available]low00aromatic ketone
2-(3,5-dimethyl-1-pyrazolyl)-1-[3-[oxo-(3-propan-2-yloxyphenyl)methyl]-1-piperidinyl]ethanone[no description available]low00aromatic ketone
[1-[(5-methyl-1-propyl-4-pyrazolyl)methyl]-3-piperidinyl]-(3-propan-2-yloxyphenyl)methanone[no description available]low00aromatic ketone
[1-[[1-(5-chloro-2-pyridinyl)-2-pyrrolyl]methyl]-3-piperidinyl]-(2,4-dimethoxyphenyl)methanone[no description available]low00aromatic ketone
2-(2-acetyl-3,5-dihydroxyphenyl)acetic acid[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone[no description available]low00aromatic ketone;
catechols;
thiocyanates
(3R,3aS,7R,7aS)-3-[3-(4-acetylphenyl)-4-fluorophenyl]-7-methyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one[no description available]low00aromatic ketone
N-(3-acetylphenyl)-5-(3-methyl-5-isoxazolyl)-2-thiophenesulfonamide[no description available]low00aromatic ketone
5-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]-1,3-dihydroindol-2-one[no description available]low00aromatic ketone
plx 4720[no description available]low00aromatic ketone;
difluorobenzene;
organochlorine compound;
pyrrolopyridine;
sulfonamide		antineoplastic agent;
B-Raf inhibitor
lcl161[no description available]low001,3-thiazoles;
aromatic ketone;
L-alanine derivative;
monofluorobenzenes;
N-acylpyrrolidine		antineoplastic agent;
apoptosis inducer
a-922500[no description available]low00aromatic ketone
marinopyrrole a[no description available]low00aromatic ketone;
organochlorine compound;
phenols;
pyrroles		antibacterial agent;
antimicrobial agent;
antineoplastic agent;
bacterial metabolite;
marine metabolite
plx4032[no description available]low00aromatic ketone;
difluorobenzene;
monochlorobenzenes;
pyrrolopyridine;
sulfonamide		antineoplastic agent;
B-Raf inhibitor
1-[2-[4-[(1-methyl-5-tetrazolyl)thio]-5-thieno[2,3-d]pyrimidinyl]phenyl]ethanone[no description available]low00aromatic ketone;
thienopyrimidine
cblc137[no description available]low00aromatic ketone;
carbazoles;
methyl ketone;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
NF-kappaB inhibitor;
p53 activator
myrtucommulone a[no description available]low00aromatic ketone
(3,4-dimethoxyphenyl)-[1-(2-phenylethyl)-3-piperidinyl]methanone[no description available]low00aromatic ketone
[1-(cyclohexylmethyl)-3-piperidinyl]-(3,4-dimethoxyphenyl)methanone[no description available]low00aromatic ketone
yk 4-279[no description available]low00aromatic ketone
1-[3-[4-[(1-methyl-5-tetrazolyl)thio]-5-thieno[2,3-d]pyrimidinyl]phenyl]ethanone[no description available]low00aromatic ketone;
thienopyrimidine
5-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]-3,3-dichloro-1H-indol-2-one[no description available]low00aromatic ketone
alectinib[no description available]low00aromatic ketone;
morpholines;
nitrile;
organic heterotetracyclic compound;
piperidines		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
4-methylethcathinone[no description available]low00aromatic ketone
3,4-dimethylmethcathinone[no description available]low00aromatic ketone
pogostone[no description available]low00aromatic ketone
ilicicolin h[no description available]low00aromatic ketone;
carbobicyclic compound;
ilicicolin;
monohydroxypyridine;
octahydronaphthalenes;
phenols;
pyridone		antimicrobial agent;
mitochondrial respiratory-chain inhibitor
[4-amino-2-[2-methoxy-4-(4-methyl-1-piperazinyl)anilino]-5-thiazolyl]-(2,6-dichlorophenyl)methanone[no description available]low00aromatic ketone
biliatresone[no description available]low00aromatic ether;
aromatic ketone;
benzodioxoles;
enone;
phenols		plant metabolite;
toxin
myxopyronin b[no description available]low00aromatic ketone
N-(4-acetylphenyl)-2-[(4-oxo-1H-quinazolin-2-yl)thio]butanamide[no description available]low00aromatic ketone
6-amino-2-[[2-(3,4-dimethylphenyl)-2-oxoethyl]thio]-1H-pyrimidin-4-one[no description available]low00aromatic ketone
3-(4-oxo-1H-quinazolin-2-yl)propanoic acid [1-(4-bromophenyl)-1-oxopropan-2-yl] ester[no description available]low00aromatic ketone
nbi 31772[no description available]low00aromatic ketone;
benzenediols;
hydroxy monocarboxylic acid;
isoquinolines;
tetrol		insulin-like growth factor-binding protein inhibitor
ConditionIndicatedRelationship StrengthStudiesTrials
Absence Seizure0low10
Absence Seizures0low10
Angel Dust Abuse0low10
Asystole0low10
Atonic Absence Seizure0low10
Atonic Absence Seizures0low10
Atonic Seizure0low10
Atonic Seizures0low10
Breast Cancer0medium11
Breast Carcinoma0medium11
Breast Neoplasms0medium11
Breast Tumors0medium11
Cancer of Breast0medium11
Cancer of the Breast0medium11
Cardiac Arrest0low10
Cardiopulmonary Arrest0low10
Chemical Dependence0low30
Chest Pain0low10
Clonic Seizure0low10
Clonic Seizures0low10
Complex Partial Seizure0low10
Complex Partial Seizures0low10
Convulsion0low10
Convulsion, Non-Epileptic0low10
Convulsions0low10
Convulsive Seizure0low10
Convulsive Seizures0low10
Drug Abuse0low30
Drug Addiction0low30
Drug Dependence0low30
Drug Habituation0low30
Drug Use Disorders0low30
Epileptic Seizure0low10
Epileptic Seizures0low10
Generalized Absence Seizure0low10
Generalized Absence Seizures0low10
Generalized Tonic-Clonic Seizures0low10
Hallucination of Body Sensation0low10
Hallucinations0low10
Hallucinations, Auditory0low10
Hallucinations, Dissociative0low10
Hallucinations, Elementary0low10
Hallucinations, Formed, of People0low10
Hallucinations, Gustatory0low10
Hallucinations, Hypnagogic0low10
Hallucinations, Hypnapompic0low10
Hallucinations, Internal Body Sensation0low10
Hallucinations, Kinesthetic0low10
Hallucinations, Mood Congruent0low10
Hallucinations, Mood Incongruent0low10
Hallucinations, Olfactory0low10
Hallucinations, Organic0low10
Hallucinations, Reflex0low10
Hallucinations, Sensory0low10
Hallucinations, Somatic0low10
Hallucinations, Tactile0low10
Hallucinations, Verbal Auditory0low10
Hallucinations, Visual0low10
Hallucinations, Visual, Formed0low10
Hallucinations, Visual, Unformed0low10
Heart Arrest0low10
Human Mammary Carcinoma0medium11
Jacksonian Seizure0low10
Malignant Neoplasm of Breast0medium11
Malignant Tumor of Breast0medium11
Mammary Cancer0medium11
Mammary Carcinoma, Human0medium11
Mammary Neoplasm, Human0medium11
Mammary Neoplasms, Human0medium11
Metastase0medium11
Metastases, Neoplasm0medium11
Metastasis0medium11
Metastasis, Neoplasm0medium11
Myoclonic Seizure0low10
Myoclonic Seizures0low10
Neoplasm Metastases0medium11
Neoplasm Metastasis0medium11
Neoplasms, Breast0medium11
Non-Epileptic Seizure0low10
Non-Epileptic Seizures0low10
Nonepileptic Seizure0low10
Nonepileptic Seizures0low10
Organic Mental Disorders, Substance-Induced0low30
Partial Seizure0low10
Partial Seizures0low10
PCP Abuse0low10
Petit Mal Convulsion0low10
Phencyclidine Abuse0low10
Phencyclidine-Related Disorders0low10
Precordial Catch0low10
Precordial Catch Syndrome0low10
Prescription Drug Abuse0low30
Psychoses, Drug0low20
Psychoses, Substance-Induced0low20
Psychoses, Toxic0low20
Seizure0low10
Seizures0low10
Seizures, Auditory0low10
Seizures, Clonic0low10
Seizures, Convulsive0low10
Seizures, Epileptic0low10
Seizures, Focal0low10
Seizures, Generalized0low10
Seizures, Gustatory0low10
Seizures, Motor0low10
Seizures, Olfactory0low10
Seizures, Sensory0low10
Seizures, Somatosensory0low10
Seizures, Tonic0low10
Seizures, Tonic-Clonic0low10
Seizures, Vertiginous0low10
Seizures, Vestibular0low10
Seizures, Visual0low10
Sensitivity and Specificity0low20
Serotonin Syndrome0low10
Single Seizure0low10
Substance Abuse0low30
Substance Addiction0low30
Substance Dependence0low30
Substance Use0low30
Substance Use Disorders0low30
Substance-Induced Psychoses0low20
Substance-Related Disorders0low30
Texidor's Twinge0low10
Tonic Clonic Seizure0low10
Tonic Seizure0low10
Tonic Seizures0low10
Tonic-Clonic Seizure0low10
Tonic-Clonic Seizures0low10
Toxic Psychoses0low20
Tumors, Breast0medium11

Research Highlights

Safety/Toxicity (1)

ArticleYear
Cytotoxicity of α-Pyrrolidinophenones: an Impact of α-Aliphatic Side-chain Length and Changes in the Plasma Membrane Fluidity.
Neurotoxicity research, Volume: 34, Issue: 3		2018
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Interactions (2)

ArticleYear
Pyrotinib or Lapatinib Combined With Capecitabine in HER2-Positive Metastatic Breast Cancer With Prior Taxanes, Anthracyclines, and/or Trastuzumab: A Randomized, Phase II Study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 10-10, Volume: 37, Issue: 29		2019
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]