Transient receptor potential cation channel subfamily V member 4

A transient receptor potential cation channel TRPV4 that is encoded in the genome of mouse. [OMA:Q9EPK8, PRO:DNx]

Synonyms

TrpV4;
Osm-9-like TRP channel 4;
OTRPC4;
Transient receptor potential protein 12;
TRP12;
Vanilloid receptor-like channel 2;
Vanilloid receptor-like protein 2;
Vanilloid receptor-related osmotically-activated channel;
VR-OA

Research

Bioassay Publications (5)

Timeframe	Studies on this Protein(%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	2 (40.00)	24.3611
2020's	2 (40.00)	2.80

Compounds (7)

Drugs with Inhibition Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
clemizole	Mus musculus (house mouse)	IC50	20.0000	1	1
hc-067047	Mus musculus (house mouse)	IC50	0.0170	2	2
rn 1734	Mus musculus (house mouse)	IC50	5.9000	2	2

Drugs with Activation Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
phorbol 12,13-dibutyrate	Mus musculus (house mouse)	EC50	22.4700	1	1
phorbol-12,13-didecanoate, (1ar-(1aalpha,1bbeta,4aalpha,7aalpha,7balpha,8alpha,9beta,9aalpha))-isomer	Mus musculus (house mouse)	EC50	2.6720	5	5
rn 1747	Mus musculus (house mouse)	EC50	0.7700	1	1
5,6-epoxy-8,11,14-eicosatrienoic acid	Mus musculus (house mouse)	EC50	0.1500	1	1