Page last updated: 2024-08-07 19:43:04
Beta-lactamase SHV-1
[no definition available]
Synonyms
EC 3.5.2.6;
PIT-2
Research
Bioassay Publications (5)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (17)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| tazobactam | Klebsiella pneumoniae | IC50 | 0.1100 | 1 | 1 |
| tazobactam | Klebsiella pneumoniae | Ki | 0.2200 | 1 | 1 |
| sulbactam | Klebsiella pneumoniae | Ki | 1.5000 | 1 | 1 |
| clavulanic acid | Klebsiella pneumoniae | IC50 | 0.1700 | 2 | 2 |
| clavulanic acid | Klebsiella pneumoniae | Ki | 2.0000 | 1 | 1 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| cephaloridine | Klebsiella pneumoniae | Km | 160.0000 | 2 | 2 |
| penicillin g | Klebsiella pneumoniae | Km | 19.5000 | 4 | 4 |
| cephalothin | Klebsiella pneumoniae | Km | 40.0000 | 2 | 2 |
| amoxicillin | Klebsiella pneumoniae | Km | 31.0000 | 2 | 2 |
| ticarcillin | Klebsiella pneumoniae | Km | 11.0000 | 2 | 2 |
| piperacillin | Klebsiella pneumoniae | Km | 24.0000 | 2 | 2 |
| doripenem | Klebsiella pneumoniae | Km | 4.3000 | 1 | 1 |
| imipenem, anhydrous | Klebsiella pneumoniae | Km | 23.0000 | 1 | 1 |
| meropenem | Klebsiella pneumoniae | Km | 4.2000 | 1 | 1 |
| cefuroxime | Klebsiella pneumoniae | Km | 80.0000 | 1 | 1 |
| cefepime | Klebsiella pneumoniae | Km | 115.0000 | 2 | 2 |
| ceftazidime | Klebsiella pneumoniae | Km | 380.6667 | 3 | 3 |
| cefotaxime | Klebsiella pneumoniae | Km | 257.0000 | 1 | 1 |
| ceftobiprole | Klebsiella pneumoniae | Km | 130.0000 | 1 | 1 |