carisoprodol has been researched along with Sensitivity and Specificity in 6 studies
Carisoprodol: A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1202)
carisoprodol : A carbamate ester that is the mono-N-isopropyl derivative of meprobamate (which is a significant metabolite). Carisoprodol interrupts neuronal communication within the reticular formation and spinal cord, resulting in sedation and alteration in pain perception. It is used as a muscle relaxant in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carisoprodol was detected in positive ion mode, whereas aspirin was detected in negative ion mode." | 1.39 | Simultaneous determination of carisoprodol and aspirin in human plasma using liquid chromatography-tandem mass spectrometry in polarity switch mode: application to a human pharmacokinetic study. ( Babu, RV; Krishnaiah, A; Kumar, IJ; Pilli, NR; Ramesh, M; Sreenivasulu, V, 2013) |
| " During this time period, different pharmacodynamic measurements were made." | 1.33 | The CYP2C19 genotype and the use of oral contraceptives influence the pharmacokinetics of carisoprodol in healthy human subjects. ( Bramness, JG; Breilid, H; Gulliksen, M; Mørland, J; Skurtveit, S; Steen, VM, 2005) |
| "Meprobamate was also found as the metabolite of carisoprodol in both urine and plasma." | 1.32 | Simultaneous determination of carisoprodol and acetaminophen in an attempted suicide by liquid chromatography-mass spectrometry with positive electrospray ionization. ( Aoki, M; Maeno, Y; Matsumoto, T; Matsuoka, T; Nagao, M; Sano, T, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Hansen, RJ | 1 |
| Samber, BJ | 1 |
| Gustafson, DL | 1 |
| Sreenivasulu, V | 1 |
| Ramesh, M | 1 |
| Kumar, IJ | 1 |
| Babu, RV | 1 |
| Pilli, NR | 1 |
| Krishnaiah, A | 1 |
| Essler, S | 1 |
| Bruns, K | 1 |
| Frontz, M | 1 |
| McCutcheon, JR | 1 |
| Matsumoto, T | 1 |
| Sano, T | 1 |
| Matsuoka, T | 1 |
| Aoki, M | 1 |
| Maeno, Y | 1 |
| Nagao, M | 1 |
| Bramness, JG | 1 |
| Skurtveit, S | 1 |
| Gulliksen, M | 1 |
| Breilid, H | 1 |
| Steen, VM | 1 |
| Mørland, J | 1 |
6 other studies available for carisoprodol and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Rapid and sensitive LC-MS/MS method for determination of felbamate in mouse plasma and tissues and human plasma.
Topics: Animals; Anticonvulsants; Brain Chemistry; Carisoprodol; Chromatography, Liquid; Felbamate; Humans; | 2010 |
Simultaneous determination of carisoprodol and aspirin in human plasma using liquid chromatography-tandem mass spectrometry in polarity switch mode: application to a human pharmacokinetic study.
Topics: Aspirin; Carisoprodol; Chromatography, High Pressure Liquid; Drug Stability; Humans; Least-Squares A | 2013 |
A rapid quantitative method of carisoprodol and meprobamate by liquid chromatography-tandem mass spectrometry.
Topics: Carisoprodol; Chromatography, High Pressure Liquid; Drug Stability; Female; Forensic Toxicology; Hum | 2012 |
Simultaneous determination of carisoprodol and acetaminophen in an attempted suicide by liquid chromatography-mass spectrometry with positive electrospray ionization.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Carisoprodol; Chromatography, Liquid; Drug Combinati | 2003 |
The CYP2C19 genotype and the use of oral contraceptives influence the pharmacokinetics of carisoprodol in healthy human subjects.
Topics: Area Under Curve; Aryl Hydrocarbon Hydroxylases; Carisoprodol; Chromatography, Liquid; Contraceptive | 2005 |