gentamicin has been researched along with Sensitivity and Specificity in 82 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate whether transient-evoked and distortion-product (DP) otoacoustic emissions (OAEs) are more sensitive than pure-tone audiometry (PTA) in revealing gentamicin-induced ototoxicity in children with cystic fibrosis (CF)." | 5.10 | Otoacoustic emissions for monitoring aminoglycoside-induced ototoxicity in children with cystic fibrosis. ( Adamopoulos, G; Apostolopoulos, N; Dinopoulou, D; Doudounakis, S; Stavroulaki, P; Vossinakis, IC, 2002) |
| " Recently, our studies have shown that ICC for drugs is extremely useful for such studies by utilizing easy and safe techniques, and gives direct evidence of drug localization." | 2.47 | [Distribution and accumulation of antibiotics in cells and tissues and toxicity studies by immunocytochemistry]. ( Fujiwara, K, 2011) |
| " Stabilizing matrices placed on the round window membrane for sustained passive delivery of compounds offer more controlled dosing profiles than transtympanic injections." | 2.44 | State-of-the-art mechanisms of intracochlear drug delivery. ( Borkholder, DA, 2008) |
| "To determine the lowest concentration of amphotericin B supplementation in Optisol-GS that will eliminate fungal contaminants effectively without resulting in toxic effects to the cornea and to determine what role light exposure plays in the efficacy and safety of amphotericin B supplementation." | 1.43 | The Effect of Light Exposure on the Efficacy and Safety of Amphotericin B in Corneal Storage Media. ( Duncan, K; Hoover, C; Jeng, BH; Parker, J, 2016) |
| "Then gentamicin was bound directly to citrate functionalised GNPs and the complex was stabilised by polyethylene glycol." | 1.43 | Gentamicin-gold nanoparticles conjugate: a contrast agent for X-ray imaging of infectious foci due to Staphylococcus aureus. ( Ahangari, A; Saghatchi, F; Salouti, M, 2016) |
| "Gentamicin is a commonly used aminoglycoside antibiotic, whose ototoxicity remains a major problem in clinical use." | 1.42 | The effect of radiotherapy on gentamicin ototoxicity: an animal model. ( Bezdjian, A; Daniel, SJ; Devic, S; Mujica-Mota, MA, 2015) |
| "Gentamicin was quantified with FTIR only (1045-1169cm(-1) and 2715-2850cm(-1)) due to interferences in UV domain of parabens, preservatives present in the commercial brand used to prepare locks." | 1.40 | Development of a Fourier transform infrared spectroscopy coupled to UV-Visible analysis technique for aminosides and glycopeptides quantitation in antibiotic locks. ( Ben Reguiga, M; Sayet, G; Sinegre, M, 2014) |
| " The dogma of gentamicin ototoxicity theorizes that (1) the toxic effects of the drug are cumulative and dose dependent, despite clinical observations of ototoxicity after a single dose, and (2) gentamicin's ototoxic effects are irreversible, although clinicians have observed improvement in hearing over time." | 1.35 | Ototoxic effects of single-dose versus 19-day daily-dose gentamicin. ( Blakley, BW; Blakley, L; Gooi, A; Hochman, J; Wellman, M, 2008) |
| " Although cell culture detects infectious virus and is a sensitive method, there are major difficulties in using this method due to the toxic effect of semen on the cells." | 1.33 | Elimination of toxicity and enhanced detection of lumpy skin disease virus on cell culture from experimentally infected bovine semen samples. ( Annandale, CH; Bagla, VP; Irons, PC; Osuagwuh, UI; Venter, EH, 2006) |
| "Gentamicin is an antibiotic added to bone cement to treat or prevent infection in arthroplasty." | 1.32 | Fatigue strength of PMMA bone cement mixed with gentamicin and barium sulphate vs pure PMMA. ( Baleani, M; Cristofolini, L; Minari, C; Toni, A, 2003) |
| "3H-thymidine incorporation was also decreased (p < 0." | 1.32 | Gentamicin may have an adverse effect on osteogenesis. ( Isefuku, S; Joyner, CJ; Simpson, AH, 2003) |
| "Gentamicin was found in native hospital wastewater in a concentration range between 0." | 1.32 | Analytical method for the determination of the aminoglycoside gentamicin in hospital wastewater via liquid chromatography-electrospray-tandem mass spectrometry. ( Löffler, D; Ternes, TA, 2003) |
| " Patients with nephrotoxicity had statistically longer treatment periods, increased cumulative dose, and more dosing predictions (P < 0." | 1.32 | The use of a change in gentamicin clearance as an early predictor of gentamicin-induced nephrotoxicity. ( Begg, EJ; Duffull, SB; Frampton, C; Kirkpatrick, CM, 2003) |
| "Anti-gentamicin antibody was immobilized in a mesoporous sol-gel material using tetramethoxysilane as a precursor and poly(ethylene glycol) as a template." | 1.31 | Flow injection fluorescence immunoassay for gentamicin using sol-gel-derived mesoporous biomaterial. ( Chen, XL; Ding, MT; Qu, HY; Xu, JG; Yang, HH; Zhu, QZ, 2002) |
| " Arbekacin may prove useful when used in combination with vancomycin in treating infections caused by gentamicin-resistant MRSA." | 1.31 | In-vitro activity of arbekacin alone and in combination with vancomycin against gentamicin- and methicillin-resistant Staphylococcus aureus. ( Chow, JW; Kariyama, R; Kumon, H; You, I; Zervos, MJ, 2000) |
| "Gentamicin is a broad-spectrum aminoglycoside antibiotic widely used in veterinary medicine for the treatment of serious infections." | 1.31 | Determination of gentamicin in swine and calf tissues by high-performance liquid chromatography combined with electrospray ionization mass spectrometry. ( Backer, PD; Baere, SD; Cherlet, M, 2000) |
| "The objective of this study is to determine the safety and efficacy of an extended interval aminoglycoside dosing guideline implemented in our neonatal intensive care unit (NICU)." | 1.31 | Use of higher dose extended interval aminoglycosides in a neonatal intensive care unit. ( Fuller, L; Menke, JA; Ohler, KH, 2000) |
| "Gentamicin was separated by RP-HPLC and detected at 365 nm after pre-column derivatization with 1-fluoro-2,4-dinitrobenzene." | 1.31 | Quantification of gentamicin in Mueller-Hinton agar by high-performance liquid chromatography. ( Arcelloni, C; Comuzzi, B; Paroni, R; Vaiani, R, 2001) |
| " In the present study, data including age, sex, height, weight, serum creatinine concentration, dose, dosing interval, and time of measurement were collected from 240 patients with various diseases being treated with gentamicin in a general hospital setting." | 1.30 | Application of a neural network for gentamicin concentration prediction in a general hospital population. ( Corrigan, BW; Jamali, F; Mayo, PR, 1997) |
| "A patient had Crohn's disease in relapse with multiple small bowel fistulae and mesenteric abscesses." | 1.30 | Relative sensitivity of Tc-99m WBC versus In-111 WBC in a patient with Crohn's disease on steroids. ( Broekelschen, P; Challa, S; Lyons, KP; Milne, N, 1997) |
| "Milk gentamicin levels were detected at post injection hours up to 120 hr in each of the two dairy cattle." | 1.29 | Dot-ELISA for the rapid detection of gentamicin in milk. ( Ara, J; Gans, Z; Sweeney, R; Wolf, B, 1995) |
| "Gentamicin was extracted from the biological matrix with high efficiency using carboxypropyl (CBA)-bonded silica." | 1.29 | Sensitive fluorimetric determination of gentamicin sulfate in biological matrices using solid-phase extraction, pre-column derivatization with 9-fluorenylmethyl chloroformate and reversed-phase high-performance liquid chromatography. ( Richards, RM; Stead, DA, 1996) |
| "gentamicin therapy were randomly selected and monitored for possible ADRs." | 1.27 | Sensitivity and specificity of three methods of detecting adverse drug reactions. ( Berry, LL; Fudge, KA; Segal, R; Sherrin, TP, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.22) | 18.7374 |
| 1990's | 22 (26.83) | 18.2507 |
| 2000's | 40 (48.78) | 29.6817 |
| 2010's | 19 (23.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, Q | 1 |
| Huang, J | 1 |
| Sun, Y | 1 |
| Deng, R | 1 |
| Teng, M | 1 |
| Li, Q | 1 |
| Yang, Y | 1 |
| Hu, X | 1 |
| Zhang, Z | 1 |
| Zhang, G | 1 |
| Webb, JC | 1 |
| Gbejuade, H | 1 |
| Lovering, A | 1 |
| Spencer, R | 1 |
| Sayet, G | 1 |
| Sinegre, M | 1 |
| Ben Reguiga, M | 1 |
| Bijleveld, Y | 1 |
| de Haan, TR | 1 |
| Toersche, J | 1 |
| Jorjani, S | 1 |
| van der Lee, J | 1 |
| Groenendaal, F | 1 |
| Dijk, P | 1 |
| van Heijst, A | 1 |
| Gavilanes, AWD | 1 |
| de Jonge, R | 1 |
| Dijkman, KP | 1 |
| van Straaten, H | 1 |
| Rijken, M | 1 |
| Zonnenberg, I | 1 |
| Cools, F | 1 |
| Nuytemans, D | 1 |
| Mathôt, R | 1 |
| Bezdjian, A | 1 |
| Mujica-Mota, MA | 1 |
| Devic, S | 1 |
| Daniel, SJ | 1 |
| Kamiya, C | 1 |
| Kimura, K | 1 |
| Doyama, Y | 1 |
| Miyazaki, A | 1 |
| Morimoto, M | 1 |
| Banno, H | 1 |
| Nagano, N | 1 |
| Jin, W | 1 |
| Wachino, J | 1 |
| Yamada, K | 1 |
| Arakawa, Y | 1 |
| Duncan, K | 1 |
| Parker, J | 1 |
| Hoover, C | 1 |
| Jeng, BH | 1 |
| Ahangari, A | 1 |
| Salouti, M | 1 |
| Saghatchi, F | 1 |
| Liu, H | 1 |
| Zhang, T | 1 |
| Wu, Q | 1 |
| Zhang, Y | 1 |
| Dai, C | 1 |
| Rebe Raz, S | 1 |
| Bremer, MG | 1 |
| Giesbers, M | 1 |
| Norde, W | 1 |
| Kühn, KD | 1 |
| Weber, C | 1 |
| Kreis, S | 1 |
| Holzgrabe, U | 1 |
| Borkholder, DA | 1 |
| Liippo, J | 1 |
| Lammintausta, K | 1 |
| Gooi, A | 1 |
| Hochman, J | 1 |
| Wellman, M | 1 |
| Blakley, L | 1 |
| Blakley, BW | 1 |
| MacDougall, HG | 1 |
| Weber, KP | 1 |
| McGarvie, LA | 1 |
| Halmagyi, GM | 1 |
| Curthoys, IS | 1 |
| Espandiari, P | 1 |
| Rosenzweig, B | 1 |
| Zhang, J | 1 |
| Zhou, Y | 1 |
| Schnackenberg, L | 1 |
| Vaidya, VS | 1 |
| Goering, PL | 1 |
| Brown, RP | 1 |
| Bonventre, JV | 1 |
| Mahjoob, K | 1 |
| Holland, RD | 1 |
| Beger, RD | 1 |
| Thompson, K | 1 |
| Hanig, J | 1 |
| Sadrieh, N | 1 |
| Sanchez-Ferrandiz, N | 1 |
| Fernandez-Gonzalez, S | 1 |
| Guillen-Grima, F | 1 |
| Perez-Fernandez, N | 1 |
| Fujiwara, K | 1 |
| Vučićević-Prčetić, K | 1 |
| Cservenák, R | 1 |
| Radulović, N | 1 |
| Sasaki, D | 1 |
| Yamada, A | 1 |
| Umeno, H | 1 |
| Kurihara, H | 1 |
| Nakatsuji, S | 1 |
| Fujihira, S | 1 |
| Tsubota, K | 1 |
| Ono, M | 1 |
| Moriguchi, A | 1 |
| Watanabe, K | 1 |
| Seki, J | 1 |
| Meyer, J | 1 |
| Piller, G | 1 |
| Spiegel, CA | 1 |
| Hetzel, S | 1 |
| Squire, M | 1 |
| Hosohata, K | 1 |
| Ando, H | 1 |
| Fujimura, A | 1 |
| Nagib, EM | 1 |
| El-Sayed, MH | 1 |
| Ahmed, MA | 1 |
| Youssef, MH | 1 |
| Kłodzińska, E | 1 |
| Jaworski, M | 1 |
| Kupczyk, W | 1 |
| Jackowski, M | 1 |
| Buszewski, B | 1 |
| Cekmen, M | 1 |
| Otunctemur, A | 1 |
| Ozbek, E | 1 |
| Cakir, SS | 1 |
| Dursun, M | 1 |
| Polat, EC | 1 |
| Somay, A | 1 |
| Ozbay, N | 1 |
| Yang, HH | 2 |
| Zhu, QZ | 1 |
| Qu, HY | 1 |
| Chen, XL | 2 |
| Ding, MT | 1 |
| Xu, JG | 2 |
| Burgess, DS | 1 |
| Nathisuwan, S | 1 |
| Baleani, M | 1 |
| Cristofolini, L | 1 |
| Minari, C | 1 |
| Toni, A | 1 |
| Isefuku, S | 1 |
| Joyner, CJ | 1 |
| Simpson, AH | 1 |
| Löffler, D | 1 |
| Ternes, TA | 1 |
| Kaczmarska, L | 1 |
| Jakoniuk, P | 1 |
| Rhomberg, PR | 1 |
| Jones, RN | 1 |
| Kirkpatrick, CM | 1 |
| Duffull, SB | 1 |
| Begg, EJ | 1 |
| Frampton, C | 1 |
| Witzmann, FA | 1 |
| Li, J | 1 |
| Ziai, SA | 1 |
| Salehian, P | 1 |
| Mahmoudian, M | 1 |
| Vlasova, II | 1 |
| Asrieli, TV | 1 |
| Gavrilova, EM | 1 |
| Danilov, VS | 1 |
| Zhang, SQ | 1 |
| Zhuang, ZX | 1 |
| Wang, XR | 1 |
| Hunfeld, KP | 1 |
| Bittner, T | 1 |
| Rödel, R | 1 |
| Brade, V | 1 |
| Cinatl, J | 1 |
| Megoulas, NC | 1 |
| Koupparis, MA | 1 |
| Kiyatake, I | 1 |
| Nakamura, T | 1 |
| Koide, H | 1 |
| Yuan, L | 1 |
| Wei, H | 1 |
| Li, SF | 1 |
| Doss, VA | 1 |
| Parvathi, S | 1 |
| Raju, BA | 1 |
| Devi, NA | 1 |
| Li, B | 1 |
| Adams, E | 1 |
| Van Schepdael, A | 3 |
| Hoogmartens, J | 3 |
| Lecároz, C | 1 |
| Campanero, MA | 1 |
| Gamazo, C | 1 |
| Blanco-Prieto, MJ | 1 |
| Bagla, VP | 1 |
| Osuagwuh, UI | 1 |
| Annandale, CH | 1 |
| Irons, PC | 1 |
| Venter, EH | 1 |
| Curiel, H | 1 |
| Vanderaerden, W | 1 |
| Velez, H | 1 |
| Park, JW | 1 |
| Hong, JS | 1 |
| Parajuli, N | 1 |
| Koh, HS | 1 |
| Park, SR | 1 |
| Lee, MO | 1 |
| Lim, SK | 1 |
| Yoon, YJ | 1 |
| Yean, CY | 1 |
| Yin, LS | 1 |
| Lalitha, P | 1 |
| Ravichandran, M | 1 |
| Giardina, WJ | 1 |
| Wismer, CT | 1 |
| Heimler, R | 1 |
| Nelin, LD | 1 |
| Billman, DO | 1 |
| Sasidharan, P | 1 |
| Vargas, J | 1 |
| Lozano, MC | 1 |
| Parras, P | 1 |
| Martín, E | 1 |
| Ara, J | 1 |
| Gans, Z | 1 |
| Sweeney, R | 1 |
| Wolf, B | 1 |
| Stead, DA | 1 |
| Richards, RM | 1 |
| Clarke, AJ | 1 |
| Francis, D | 1 |
| Keenleyside, WJ | 1 |
| Corrigan, BW | 1 |
| Mayo, PR | 1 |
| Jamali, F | 1 |
| Lyons, KP | 2 |
| Challa, S | 2 |
| Broekelschen, P | 2 |
| Milne, N | 2 |
| Bhogte, CP | 1 |
| Patravale, VB | 1 |
| Devarajan, PV | 1 |
| Sachetelli, S | 1 |
| Beaulac, C | 1 |
| Lagacé, J | 1 |
| Reljic, M | 1 |
| Gorisek, B | 1 |
| Kolosova, AIu | 1 |
| Blintsov, AN | 1 |
| Samsonova, ZhV | 1 |
| Egorov, AM | 2 |
| Dunne, WM | 1 |
| Holland-Staley, CA | 1 |
| Hirvonen, TP | 1 |
| Pyykkö, I | 1 |
| Aalto, H | 1 |
| Silverstein, H | 1 |
| Wan, QH | 1 |
| Le, XC | 1 |
| Yusuf, A | 1 |
| Al-Rawithi, S | 1 |
| Raines, D | 1 |
| Frayha, H | 1 |
| Toonsi, TA | 1 |
| Al-Mohsen, I | 1 |
| E1-Yazigi, A | 1 |
| Frutos, P | 1 |
| Torrado, S | 1 |
| Perez-Lorenzo, ME | 1 |
| Frutos, G | 1 |
| You, I | 1 |
| Kariyama, R | 1 |
| Zervos, MJ | 1 |
| Kumon, H | 1 |
| Chow, JW | 1 |
| Kaale, E | 1 |
| Leonard, S | 1 |
| Roets, E | 1 |
| Cherlet, M | 1 |
| Baere, SD | 1 |
| Backer, PD | 1 |
| Ohler, KH | 1 |
| Menke, JA | 1 |
| Fuller, L | 1 |
| Vogel, R | 1 |
| DeFillipo, K | 1 |
| Reif, V | 1 |
| Musella, M | 1 |
| Guido, A | 1 |
| Musella, S | 1 |
| Arcelloni, C | 1 |
| Comuzzi, B | 1 |
| Vaiani, R | 1 |
| Paroni, R | 1 |
| Brun, S | 1 |
| Bouchara, JP | 1 |
| Bocquel, A | 1 |
| Basile, AM | 1 |
| Contet-Audonneau, N | 1 |
| Chabasse, D | 1 |
| Leverstein-van Hall, MA | 1 |
| Fluit, AC | 1 |
| Blok, HE | 1 |
| Box, AT | 1 |
| Peters, ED | 1 |
| Weersink, AJ | 1 |
| Verhoef, J | 1 |
| Stavroulaki, P | 1 |
| Vossinakis, IC | 1 |
| Dinopoulou, D | 1 |
| Doudounakis, S | 1 |
| Adamopoulos, G | 1 |
| Apostolopoulos, N | 1 |
| Klein, J | 1 |
| Koren, G | 1 |
| MacLeod, SM | 1 |
| Gavrilov, VB | 1 |
| Eremin, SA | 1 |
| Brakstad, OG | 1 |
| Aasbakk, K | 1 |
| Maeland, JA | 1 |
| Weissmann, D | 1 |
| Spargo, J | 1 |
| Wennersten, C | 1 |
| Ferraro, MJ | 1 |
| Berry, LL | 1 |
| Segal, R | 1 |
| Sherrin, TP | 1 |
| Fudge, KA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-masked, Placebo-controlled Study of the Safety of Amphotericin 0.255 μg/mL in Optisol-GS[NCT04018417] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2019-07-03 | Withdrawn (stopped due to Reconsidered significance in light of newly published in vitro data.) | ||
| Feasibility and Safety of a Telemedically Performed Three-Component Oculomotor Testing Battery (HINTS) in Healthy Adults[NCT02938221] | 30 participants (Actual) | Interventional | 2016-10-31 | Completed | |||
| Randomized Control Trial of Vancomycin Powder Following Posterior Instrumented Spinal Surgery for Trauma[NCT01977989] | Phase 4 | 140 participants (Anticipated) | Interventional | 2013-10-31 | Enrolling by invitation | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for gentamicin and Sensitivity and Specificity
| Article | Year |
|---|---|
State-of-the-art mechanisms of intracochlear drug delivery.
Topics: Adrenal Cortex Hormones; Animals; Cochlea; Dose-Response Relationship, Drug; Drug Administration Sch | 2008 |
[Distribution and accumulation of antibiotics in cells and tissues and toxicity studies by immunocytochemistry].
Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Cells; Gentamicins; Hair Follicle; Immunohistochemistry | 2011 |
Proteomics and nephrotoxicity.
Topics: Drug-Related Side Effects and Adverse Reactions; Electrophoresis, Gel, Two-Dimensional; Gentamicins; | 2004 |
Use of a new device, the MicroWick, to deliver medication to the inner ear.
Topics: Anti-Bacterial Agents; Autoimmune Diseases; Dexamethasone; Drug Delivery Systems; Ear Diseases; Ear, | 1999 |
4 trials available for gentamicin and Sensitivity and Specificity
| Article | Year |
|---|---|
Identification of sepsis in neonates following maternal antibiotic therapy.
Topics: Ampicillin; Female; Gentamicins; Humans; Infant, Newborn; Labor, Obstetric; Latex Fixation Tests; Le | 1995 |
C-reactive protein and the treatment of pelvic inflammatory disease.
Topics: Abscess; Adult; Blood Sedimentation; Body Temperature; C-Reactive Protein; Ceftriaxone; Clindamycin; | 1998 |
Collagen tampons as aminoglycoside carriers to reduce postoperative infection rate in prosthetic repair of groin hernias.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Collagen; Drug Carriers; Femal | 2001 |
Otoacoustic emissions for monitoring aminoglycoside-induced ototoxicity in children with cystic fibrosis.
Topics: Adolescent; Anti-Bacterial Agents; Audiometry, Evoked Response; Audiometry, Pure-Tone; Case-Control | 2002 |
74 other studies available for gentamicin and Sensitivity and Specificity
| Article | Year |
|---|---|
A SERS-based multiple immuno-nanoprobe for ultrasensitive detection of neomycin and quinolone antibiotics via a lateral flow assay.
Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Biological Assay; Biosensing Techniques; Contrast Med | 2018 |
Characterisation of in vivo release of gentamicin from polymethyl methacrylate cement using a novel method.
Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Biocompatible Materials; Biomarkers; Bone Cem | 2013 |
Development of a Fourier transform infrared spectroscopy coupled to UV-Visible analysis technique for aminosides and glycopeptides quantitation in antibiotic locks.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Calibration; Catheter-Related Infections; Catheter | 2014 |
A simple quantitative method analysing amikacin, gentamicin, and vancomycin levels in human newborn plasma using ion-pair liquid chromatography/tandem mass spectrometry and its applicability to a clinical study.
Topics: Amikacin; Chromatography, Liquid; Drug Stability; Gentamicins; Humans; Infant, Newborn; Reproducibil | 2014 |
The effect of radiotherapy on gentamicin ototoxicity: an animal model.
Topics: Animals; Biopsy, Needle; Cochlea; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Res | 2015 |
Ceftibuten-containing agar plate for detecting group B streptococci with reduced penicillin susceptibility (PRGBS).
Topics: Agar; Anti-Bacterial Agents; Bacteriological Techniques; Ceftibuten; Cephalosporins; Culture Media; | 2015 |
The Effect of Light Exposure on the Efficacy and Safety of Amphotericin B in Corneal Storage Media.
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Cell Survival; Chondroitin Sulfates; Colony Cou | 2016 |
Gentamicin-gold nanoparticles conjugate: a contrast agent for X-ray imaging of infectious foci due to Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Contrast Media; Gentamicins; Gold; Metal Nanoparticles; Mice; Mice, | 2016 |
End-point indicators of low-dose intra-tympanic gentamicin in management of Ménière's disease.
Topics: Adult; Aged; Female; Gentamicins; Head Impulse Test; Humans; Injection, Intratympanic; Male; Meniere | 2017 |
Development of a biosensor microarray towards food screening, using imaging surface plasmon resonance.
Topics: Biosensing Techniques; Equipment Design; Equipment Failure Analysis; Food Analysis; Food Contaminati | 2008 |
Evaluation of the stability of gentamicin in different antibiotic carriers using a validated MEKC method.
Topics: Anti-Bacterial Agents; beta-Cyclodextrins; Borates; Chromatography, Micellar Electrokinetic Capillar | 2008 |
Positive patch test reactions to gentamicin show sensitization to aminoglycosides from topical therapies, bone cements, and from systemic medication.
Topics: Administration, Topical; Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Aminoglycosid | 2008 |
Ototoxic effects of single-dose versus 19-day daily-dose gentamicin.
Topics: Animals; Auditory Threshold; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administ | 2008 |
The video head impulse test: diagnostic accuracy in peripheral vestibulopathy.
Topics: Adult; Anti-Bacterial Agents; Case-Control Studies; Female; Fixation, Ocular; Gentamicins; Head Move | 2009 |
Age-related differences in susceptibility to cisplatin-induced renal toxicity.
Topics: Age Factors; Aging; Animals; Biomarkers; Child; Cisplatin; Disease Susceptibility; Gentamicins; Huma | 2010 |
Intractable Ménière's disease. Modelling of the treatment by means of statistical analysis.
Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Diagnosis, Differential; Disability Evaluatio | 2010 |
Development and validation of liquid chromatography tandem mass spectrometry methods for the determination of gentamicin, lincomycin, and spectinomycin in the presence of their impurities in pharmaceutical formulations.
Topics: Aminoglycosides; Calibration; Chromatography, Liquid; Drug Contamination; Gentamicins; Humans; Linco | 2011 |
Comparison of the course of biomarker changes and kidney injury in a rat model of drug-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; beta 2-Microglobulin; Biomarkers; Blood Urea Nitrogen; Calbindins; Cel | 2011 |
Vacuum-mixing significantly changes antibiotic elution characteristics of commercially available antibiotic-impregnated bone cements.
Topics: Anti-Bacterial Agents; Arthroplasty, Replacement; Bone Cements; Drug Delivery Systems; Evidence-Base | 2011 |
Urinary vanin-1 as a novel biomarker for early detection of drug-induced acute kidney injury.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Amidohydrolases; Animals; beta-N-Acetyl-Galactosaminidase | 2012 |
Intestinal motility in acute uremia and effects of erythropoietin.
Topics: Acute Disease; Animals; Colon; Creatinine; Disease Models, Animal; Duodenum; Erythropoietin; Female; | 2012 |
A study of interactions between bacteria and antibiotics by capillary electrophoresis.
Topics: Anti-Bacterial Agents; Bacteria; Bacteriological Techniques; Bacteriuria; Electrophoresis, Capillary | 2012 |
Pomegranate extract attenuates gentamicin-induced nephrotoxicity in rats by reducing oxidative stress.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Biopsy, Needle; Chi-Square Distribution; Disease | 2013 |
Flow injection fluorescence immunoassay for gentamicin using sol-gel-derived mesoporous biomaterial.
Topics: Adsorption; Antibodies, Monoclonal; Binding, Competitive; Biocompatible Materials; Calibration; Chro | 2002 |
Cefepime, piperacillin/tazobactam, gentamicin, ciprofloxacin, and levofloxacin alone and in combination against Pseudomonas aeruginosa.
Topics: Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Drug Therapy, Combination; Gent | 2002 |
Fatigue strength of PMMA bone cement mixed with gentamicin and barium sulphate vs pure PMMA.
Topics: Anti-Bacterial Agents; Barium Sulfate; Bone Cements; Cementation; Contrast Media; Gentamicins; Mater | 2003 |
Gentamicin may have an adverse effect on osteogenesis.
Topics: Aged; Alkaline Phosphatase; Cell Division; Cells, Cultured; Culture Media, Conditioned; DNA; Dose-Re | 2003 |
Analytical method for the determination of the aminoglycoside gentamicin in hospital wastewater via liquid chromatography-electrospray-tandem mass spectrometry.
Topics: Anti-Bacterial Agents; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Gentamicins; Hos | 2003 |
[Therapeutic effect of some antibiotics on experimental staphylococcal infection and its correlation with in vitro activity of antibiotics in sub-inhibitory concentration against Staphylococcus aureus strains].
Topics: Animals; Anti-Bacterial Agents; Cloxacillin; Drug Administration Schedule; Gentamicins; Leukocytes; | 2003 |
Antimicrobial spectrum of activity for meropenem and nine broad spectrum antimicrobials: report from the MYSTIC Program (2002) in North America.
Topics: Anti-Bacterial Agents; Aztreonam; Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Bacteria | 2003 |
The use of a change in gentamicin clearance as an early predictor of gentamicin-induced nephrotoxicity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Creatinine; Female; Gentamicins; Humans; Kidney; Male; M | 2003 |
Study of serum and tissues angiotensin converting enzyme (ACE) activity in rat with gentamicin induced renal toxicity.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Biomarkers; Biopsy, Needle; Chromatography, High | 2003 |
New approach for specific determination of antibiotics by use of luminescent Escherichia coli and immune serum.
Topics: Anti-Bacterial Agents; Escherichia coli; Gentamicins; Humans; Immune Sera; Luminescent Measurements; | 2004 |
Magnetite-containing spherical silica nanoparticles for biocatalysis and bioseparations.
Topics: Adsorption; Calibration; Catalysis; Chemistry Techniques, Analytical; Emulsions; Enzyme Stability; F | 2004 |
New real-time PCR-based method for in vitro susceptibility testing of Anaplasma phagocytophilum against antimicrobial agents.
Topics: Ampicillin; Anaplasma phagocytophilum; Anti-Bacterial Agents; Aza Compounds; Azithromycin; DNA, Bact | 2004 |
Development and validation of a novel LC/ELSD method for the quantitation of gentamicin sulfate components in pharmaceuticals.
Topics: Chromatography, Liquid; Gentamicins; Pharmaceutical Preparations; Quality Control; Reference Standar | 2004 |
Urinary guanidinoacetic acid excretion as an indicator of gentamicin nephrotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Biomarkers; Early Diagnosis; Gentamicins; Glycine; Kidney Diseases; | 2004 |
Direct determination of gentamicin components by capillary electrophoresis with potential gradient detection.
Topics: Electrophoresis, Capillary; Gentamicins; Molecular Structure; Sensitivity and Specificity | 2005 |
Evaluation on the use of beta-lactamase and aminoglycoside modifying enzyme gene sequences as markers for the early detection of antibiotic resistance profile of Pseudomonas aeruginosa.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactamases; Biomarkers | 2004 |
Analysis of unknown compounds in gentamicin bulk samples with liquid chromatography coupled with ion trap mass spectrometry.
Topics: Anti-Bacterial Agents; Chromatography, Liquid; Drug Contamination; Gentamicins; Mass Spectrometry; M | 2006 |
Determination of gentamicin in different matrices by a new sensitive high-performance liquid chromatography-mass spectrometric method.
Topics: Animals; Anti-Bacterial Agents; Biological Assay; Calibration; Chemistry Techniques, Analytical; Chr | 2006 |
Elimination of toxicity and enhanced detection of lumpy skin disease virus on cell culture from experimentally infected bovine semen samples.
Topics: Animals; Cattle; Centrifugation; Epithelial Cells; Filtration; Gentamicins; Kaolin; Lumpy Skin Disea | 2006 |
Analysis of underivatized gentamicin by capillary electrophoresis with UV detection.
Topics: Anti-Bacterial Agents; Cetrimonium; Cetrimonium Compounds; Diphosphates; Electrolytes; Electrophores | 2007 |
Analytical profiling of biosynthetic intermediates involved in the gentamicin pathway of Micromonospora echinospora by high-performance liquid chromatography using electrospray ionization mass spectrometric detection.
Topics: Aminoglycosides; Anti-Bacterial Agents; Cells, Cultured; Chromatography, High Pressure Liquid; Genta | 2007 |
A nanoplex PCR assay for the rapid detection of vancomycin and bifunctional aminoglycoside resistance genes in Enterococcus species.
Topics: Aminoglycosides; Anti-Bacterial Agents; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Ent | 2007 |
The rat-pull test procedure: a method for assessing the strength of rats.
Topics: Acrylamide; Acrylamides; Animals; Diazepam; Ergometry; Evaluation Studies as Topic; Gentamicins; Mal | 1995 |
[Comparison of ATB STREP, AMS-Vitek GPS-TA, and disk diffusion for the detection of a high level of aminoglycoside resistance in Enterococcus spp].
Topics: Diffusion; Drug Resistance, Microbial; Drug Synergism; Enterococcus; Gentamicins; Humans; Microbial | 1993 |
Dot-ELISA for the rapid detection of gentamicin in milk.
Topics: Animals; Anti-Bacterial Agents; Antibody Specificity; Cattle; Cross Reactions; Enzyme-Linked Immunos | 1995 |
Sensitive fluorimetric determination of gentamicin sulfate in biological matrices using solid-phase extraction, pre-column derivatization with 9-fluorenylmethyl chloroformate and reversed-phase high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Fluorenes; Gentamicins; Hydrogen-Ion Concentration; Reproducib | 1996 |
The prevalence of gentamicin 2'-N-acetyltransferase in the Proteeae and its role in the O-acetylation of peptidoglycan.
Topics: Acetylation; Acetyltransferases; Anti-Bacterial Agents; Blotting, Southern; Escherichia coli; Gene E | 1996 |
Application of a neural network for gentamicin concentration prediction in a general hospital population.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Child; Child, Preschool; Female; | 1997 |
Relative sensitivity of Tc-99m WBC versus In-111 WBC in a patient with Crohn's disease on steroids.
Topics: Abdominal Abscess; Adult; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammator | 1997 |
Fluorodensitometric evaluation of gentamicin from plasma and urine by high-performance thin-layer chromatography.
Topics: Anti-Bacterial Agents; Chromatography, Thin Layer; Gentamicins; Humans; Reproducibility of Results; | 1997 |
Relative sensitivity of Tc-99m WBC versus In-111 WBC in a patient with Crohn disease and steroid use.
Topics: Abdominal Abscess; Adult; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammator | 1997 |
Aminoglycoside detection using a universal ELISA binding procedure onto polystyrene microtiter plates in comparison with HPLC analysis and microbiological agar-diffusion assay.
Topics: Agar; Alcian Blue; Aminoglycosides; Antibodies; Calibration; Chromatography, High Pressure Liquid; C | 1998 |
[Development of a solid-phase immunoenzyme analysis of gentamicin in human blood serum].
Topics: Anti-Bacterial Agents; Calibration; Drug Stability; Gentamicins; Humans; Immunoenzyme Techniques; Li | 1998 |
Comparison of NNA agar culture and selective broth culture for detection of group B streptococcal colonization in women.
Topics: Carrier State; Cervix Uteri; Colony Count, Microbial; Culture Media; Enterococcus faecalis; Female; | 1998 |
A head autorotation test for patients with Menière's disease.
Topics: Adult; Aged; Aged, 80 and over; Caloric Tests; Combined Modality Therapy; Ear, Inner; Female; Gentam | 1998 |
Capillary electrophoretic immunoassays for digoxin and gentamicin with laser-induced fluorescence polarization detection.
Topics: Anti-Arrhythmia Agents; Binding, Competitive; Buffers; Digoxin; Electrophoresis, Capillary; Fluoresc | 1999 |
Simplified high-performance liquid chromatographic method for the determination of gentamicin sulfate in a microsample of plasma: comparison with fluorescence polarization immunoassay.
Topics: Chromatography, High Pressure Liquid; Cross Reactions; Fluorenes; Fluorescence; Fluorescence Polariz | 1999 |
A validated quantitative colorimetric assay for gentamicin.
Topics: Colorimetry; Gentamicins; Hydrogen-Ion Concentration; Kinetics; Ninhydrin; Reproducibility of Result | 2000 |
In-vitro activity of arbekacin alone and in combination with vancomycin against gentamicin- and methicillin-resistant Staphylococcus aureus.
Topics: Aminoglycosides; Anti-Bacterial Agents; Base Sequence; Dibekacin; DNA, Bacterial; Drug Interactions; | 2000 |
Capillary electrophoresis analysis of gentamicin sulphate with UV detection after pre-capillary derivatization with 1,2-phthalic dicarboxaldehyde and mercaptoacetic acid.
Topics: Electrophoresis, Capillary; Gentamicins; Methanol; Phthalic Acids; Sensitivity and Specificity; Spec | 2000 |
Determination of gentamicin in swine and calf tissues by high-performance liquid chromatography combined with electrospray ionization mass spectrometry.
Topics: Animals; Anti-Bacterial Agents; Calibration; Cattle; Chromatography, High Pressure Liquid; Gentamici | 2000 |
Use of higher dose extended interval aminoglycosides in a neonatal intensive care unit.
Topics: Anti-Bacterial Agents; Bacterial Infections; Dose-Response Relationship, Drug; Drug Administration S | 2000 |
Determination of isepamicin sulfate and related compounds by high performance liquid chromatography using evaporative light scattering detection.
Topics: Anti-Bacterial Agents; Carbohydrate Conformation; Carbohydrate Sequence; Chromatography, High Pressu | 2001 |
Quantification of gentamicin in Mueller-Hinton agar by high-performance liquid chromatography.
Topics: Agar; Chromatography, High Pressure Liquid; Diffusion; Gentamicins; Kinetics; Pseudomonas aeruginosa | 2001 |
Evaluation of five commercial Sabouraud gentamicin-chloramphenicol agar media.
Topics: Agar; Chloramphenicol; Culture Media, Conditioned; Fungi; Gentamicins; Glucose; Humans; Sensitivity | 2001 |
Control of nosocomial multiresistant Enterobacteriaceae using a temporary restrictive antibiotic agent policy.
Topics: Cross Infection; Drug Resistance, Multiple; Enterobacteriaceae; Enterobacteriaceae Infections; Genta | 2001 |
Comparison of methods for prediction of nephrotoxicity during development.
Topics: Aging; Amikacin; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Ge | 1992 |
[A comparative analysis of the immunochemical determination of gentamycin by fluorescence polarization and quenching].
Topics: Drug Monitoring; Evaluation Studies as Topic; Fluorescence Polarization Immunoassay; Gentamicins; Hu | 1992 |
Detection of Staphylococcus aureus by polymerase chain reaction amplification of the nuc gene.
Topics: Base Sequence; Body Fluids; Cloxacillin; Genes, Bacterial; Gentamicins; Humans; Molecular Sequence D | 1992 |
Detection of enterococcal high-level aminoglycoside resistance with MicroScan freeze-dried panels containing newly modified medium and Vitek Gram-Positive Susceptibility cards.
Topics: Aminoglycosides; Drug Resistance, Microbial; Enterococcus faecalis; Evaluation Studies as Topic; Gen | 1991 |
Sensitivity and specificity of three methods of detecting adverse drug reactions.
Topics: Algorithms; Computers; Data Collection; Digoxin; Drug-Related Side Effects and Adverse Reactions; Ge | 1988 |