Proteins > Type-1 angiotensin II receptor
Page last updated: 2024-08-07 13:49:01
Type-1 angiotensin II receptor
[no definition available]
Synonyms
Angiotensin II type-1 receptor;
AT1
Research
Bioassay Publications (4)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (4)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| losartan | Cavia porcellus (domestic guinea pig) | IC50 | 0.0180 | 1 | 1 |
| exp7711 | Cavia porcellus (domestic guinea pig) | IC50 | 0.4300 | 1 | 1 |
| ici d8731 | Cavia porcellus (domestic guinea pig) | IC50 | 0.0307 | 3 | 3 |
| losartan potassium | Cavia porcellus (domestic guinea pig) | IC50 | 0.0180 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| losartan | Cavia porcellus (domestic guinea pig) | Kd | 0.0126 | 1 | 1 |
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.Bioorganic & medicinal chemistry, , Dec-15, Volume: 18, Issue:24, 2010
New nonpeptide angiotensin II receptor antagonists. 3. Synthesis, biological properties, and structure-activity relationships of 2-alkyl-4-(biphenylylmethoxy)pyridine derivatives.Journal of medicinal chemistry, , Apr-30, Volume: 36, Issue:9, 1993
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.Journal of medicinal chemistry, , Feb-02, Volume: 39, Issue:3, 1996
New nonpeptide angiotensin II receptor antagonists. 3. Synthesis, biological properties, and structure-activity relationships of 2-alkyl-4-(biphenylylmethoxy)pyridine derivatives.Journal of medicinal chemistry, , Apr-30, Volume: 36, Issue:9, 1993
New nonpeptide angiotensin II receptor antagonists. 2. Synthesis, biological properties, and structure-activity relationships of 2-alkyl-4-(biphenylylmethoxy)quinoline derivatives.Journal of medicinal chemistry, , Oct-30, Volume: 35, Issue:22, 1992