Page last updated: 2024-12-11
rotundone
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
rotundone: has a spicy aroma; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 5321003 |
CHEBI ID | 191710 |
SCHEMBL ID | 180456 |
MeSH ID | M0523299 |
Synonyms (17)
Synonym |
---|
rotundone |
CHEBI:191710 |
18374-76-0 |
(3s,5r,8s)-3,8-dimethyl-5-prop-1-en-2-yl-3,4,5,6,7,8-hexahydro-2h-azulen-1-one |
SCHEMBL180456 |
NUWMTBMCSQWPDG-SDDRHHMPSA-N |
guaia-1(5),11-dien-2-one, (-)- |
(-)-rotundone |
(3s,5r,8s)-5-isopropenyl-3,8-dimethyl-3,4,5,6,7,8-hexahydro-1(2h)-azulenone |
u33h52bq0p , |
fema no. 4867 |
3,8-dimethyl-5-prop-1-en-2-yl-3,4,5,6,7,8-hexahydro-2h-azulen-1-one, (3s,5r,8s)- |
unii-u33h52bq0p |
Q15424773 |
rotundone - 90% |
XR175543 |
DTXSID301030485 |
Research Excerpts
Overview
Rotundone is an oxygenated sesquiterpene belonging to the family of guaianes. It gives the 'peppery' aroma to white and black pepper and to red wines.
Effects
Excerpt | Reference | Relevance |
---|---|---|
"Rotundone has an odor activity value in pepper on the order of 50000-250000 and is, on this criterion, by far the most powerful aroma compound yet found in that most important spice." | ( From wine to pepper: rotundone, an obscure sesquiterpene, is a potent spicy aroma compound. Capone, DL; Eggers, M; Elsey, GM; Herderich, MJ; Krammer, G; Meier, M; Parker, M; Pollnitz, AP; Sefton, MA; Siebert, TE; Vössing, T; Widder, S; Wood, C, 2008) | 1.39 |
"Rotundone has an odor activity value in pepper on the order of 50000-250000 and is, on this criterion, by far the most powerful aroma compound yet found in that most important spice." | ( From wine to pepper: rotundone, an obscure sesquiterpene, is a potent spicy aroma compound. Capone, DL; Eggers, M; Elsey, GM; Herderich, MJ; Krammer, G; Meier, M; Parker, M; Pollnitz, AP; Sefton, MA; Siebert, TE; Vössing, T; Widder, S; Wood, C, 2008) | 1.39 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Drug Classes (1)
Class | Description |
---|---|
sesquiterpenoid | Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (20)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (10.00) | 29.6817 |
2010's | 15 (75.00) | 24.3611 |
2020's | 3 (15.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 42.55
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (42.55) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 1 (5.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 19 (95.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |