Page last updated: 2024-11-04

tetracaine and Sensitivity and Specificity

tetracaine has been researched along with Sensitivity and Specificity in 12 studies

Tetracaine: A potent local anesthetic of the ester type used for surface and spinal anesthesia.
tetracaine : A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"Tetracaine was extracted from tape with 100% methanol, which was then diluted to 50% with water for injection."1.40Development of HPLC-UV method for rapid and sensitive analysis of topically applied tetracaine: its comparison with a CZE method. ( Al-Otaibi, F; Ghazaly, E; Johnston, A; Perrett, D, 2014)
"Procaine was the internal standard."1.35Rapid analysis of tetracaine for a tape stripping pharmacokinetic study using short-end capillary electrophoresis. ( Al-Otaibi, F; Johnston, A; Perrett, D; Tucker, AT, 2009)
"Tetracaine was analyzed without derivatization, and the metabolite was analyzed after tert-butylolimethylsilyl derivatization."1.31Sensitive and selective determination of tetracaine and its metabolite in human samples by gas chromatography-mass spectrometry. ( Hino, Y; Ikeda, N; Kudo, K; Tsuji, A, 2000)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's2 (16.67)18.2507
2000's6 (50.00)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al-Otaibi, F2
Ghazaly, E1
Johnston, A2
Perrett, D2
del Mar LópezGuerrero, M1
Hernández-Mesa, M1
Cruces-Blanco, C1
García-Campaña, AM1
Fidani, M1
Gamberini, MC1
Pasello, E1
Palazzoli, F1
Dimasi, T1
Montana, M1
COWAN, TW1
Qin, M1
Liu, S1
Liu, Z1
Hu, X1
Tucker, AT1
Qin, WW1
Jiao, Z1
Zhong, MK1
Shi, XJ1
Zhang, J1
Li, ZD1
Cui, XY1
White, BJ1
Legako, JA1
Harmon, HJ1
Abe, E1
Delamoye, M1
Mathieu, B1
Durigon, M1
de Mazancourt, P1
Advenier, C1
Alvarez, JC1
Ben-David, B1
Vaida, S1
Gaitini, L1
Terada, M1
Islam, MN1
Tun, Z1
Honda, K1
Wakasugi, C1
Shinozuka, T1
Yanagida, J1
Yamamoto, T1
Kuroiwa, Y1
Hino, Y1
Ikeda, N1
Kudo, K1
Tsuji, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Caudal Anesthesia Block on Perioperative Pain Control and Reduction of the Anesthetic Agent in Pediatric Infra-umbilical Surgery: A Prospective Randomized Trial Study[NCT05581940]72 participants (Actual)Observational [Patient Registry]2020-01-05Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for tetracaine and Sensitivity and Specificity

ArticleYear
The influence of high spinal anesthesia on sensitivity to midazolam sedation.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:3

    Topics: Adult; Anesthesia, Spinal; Drug Interactions; Female; Humans; Hysterectomy; Injections, Intravenous;

1995

Other Studies

11 other studies available for tetracaine and Sensitivity and Specificity

ArticleYear
Development of HPLC-UV method for rapid and sensitive analysis of topically applied tetracaine: its comparison with a CZE method.
    Biomedical chromatography : BMC, 2014, Volume: 28, Issue:6

    Topics: Anesthetics, Local; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Sensitivity an

2014
On-line preconcentration strategy for the simultaneous quantification of three local anesthetics in human urine using CZE.
    Electrophoresis, 2015, Volume: 36, Issue:23

    Topics: Anesthetics, Local; Bupivacaine; Electrophoresis, Capillary; Female; Humans; Lidocaine; Limit of Det

2015
Development of a liquid chromatography-tandem mass spectrometry method for an euthanasic veterinarian drug: Tanax.
    Journal of pharmaceutical and biomedical analysis, 2008, Nov-04, Volume: 48, Issue:3

    Topics: Amides; Animals; Chromatography, Liquid; Cyclohexanes; Drug Combinations; Drug Stability; Euthanasia

2008
A case of a sensitivity of 0.5 percent pontacaine instilled locally.
    Proceedings of the staff meetings. Honolulu. Clinic, 1948, Volume: 14, Issue:6

    Topics: Humans; Sensitivity and Specificity; Tetracaine

1948
Resonance Rayleigh scattering spectra, non-linear scattering spectra of tetracaine hydrochloride-erythrosin system and its analytical application.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2009, Volume: 71, Issue:5

    Topics: Anesthetics, Local; Chemistry Techniques, Analytical; Diagnostic Techniques and Procedures; Drug Sta

2009
Rapid analysis of tetracaine for a tape stripping pharmacokinetic study using short-end capillary electrophoresis.
    Biomedical chromatography : BMC, 2009, Volume: 23, Issue:5

    Topics: Anesthetics, Local; Electrophoresis, Capillary; Humans; Procaine; Reference Standards; Reproducibili

2009
Simultaneous determination of procaine, lidocaine, ropivacaine, tetracaine and bupivacaine in human plasma by high-performance liquid chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, May-01, Volume: 878, Issue:15-16

    Topics: Amides; Bupivacaine; Chromatography, High Pressure Liquid; Drug Stability; Humans; Least-Squares Ana

2010
Extended lifetime of reagentless detector for multiple inhibitors of acetylcholinesterase.
    Biosensors & bioelectronics, 2003, Volume: 18, Issue:5-6

    Topics: Acetylcholinesterase; Binding, Competitive; Biosensing Techniques; Cholinesterase Inhibitors; Diazin

2003
A rapid and sensitive high-performance liquid chromatography method for determination of embutramide (a Tanax or T61 component) in human blood with photodiode-array UV detection.
    Journal of analytical toxicology, 2004, Volume: 28, Issue:2

    Topics: Adult; Amides; Chromatography, High Pressure Liquid; Drug Combinations; Forensic Medicine; Gas Chrom

2004
Determination of ester-type local anesthetic drugs (procaine, tetracaine, and T-caine) in human serum by wide-bore capillary gas chromatography with nitrogen-phosphorus detection.
    Journal of analytical toxicology, 1996, Volume: 20, Issue:5

    Topics: 4-Aminobenzoic Acid; Anesthetics, Local; Humans; Nitrogen; para-Aminobenzoates; Phosphorus; Procaine

1996
Sensitive and selective determination of tetracaine and its metabolite in human samples by gas chromatography-mass spectrometry.
    Journal of analytical toxicology, 2000, Volume: 24, Issue:3

    Topics: 4-Aminobenzoic Acid; Adipose Tissue; Anesthetics, Local; Brain Chemistry; Dibucaine; Gas Chromatogra

2000