Page last updated: 2024-08-07 11:21:07
Alpha-mannosidase
[no definition available]
Synonyms
JBM;
Jbalpha-man;
EC 3.2.1.24
Research
Bioassay Publications (7)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 5 (71.43) | 2.80 |
Compounds (7)
Drugs with Inhibition Measurements
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| miglitol | Canavalia ensiformis (jack bean) | Kd | 105.1300 | 1 | 1 |
Multivalent glucosidase inhibitors based on perylene bisimide and iminosugar conjugates.European journal of medicinal chemistry, , Nov-05, Volume: 241, 2022
Positional Isomeric Effects on the Optical Properties, Multivalent Glycosidase Inhibition Effect, and Hypoglycemic Effect of Perylene Bisimide-deoxynojirimycin Conjugates.Journal of medicinal chemistry, , 05-13, Volume: 64, Issue:9, 2021
Polyhydroxylated azetidine iminosugars: Synthesis, glycosidase inhibitory activity and molecular docking studies.Bioorganic & medicinal chemistry letters, , 12-01, Volume: 27, Issue:23, 2017
trans, trans-2-C-Aryl-3,4-dihydroxypyrrolidines as potent and selective β-glucosidase inhibitors: Pharmacological chaperones for Gaucher disease.European journal of medicinal chemistry, , Aug-05, Volume: 238, 2022
Design, synthesis and glycosidase inhibition of C-4 branched LAB and DAB derivatives.European journal of medicinal chemistry, , Apr-05, Volume: 233, 2022