zopiclone has been researched along with Sensitivity and Specificity in 13 studies
zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007
zopiclone : A pyrrolo[3,4-b]pyrazine compound having a 4-methylpiperazine-1-carboxyl group at the 5-position, a 5-chloropyridin-2-yl group at the 6-position and an oxo-substituent at the 7-position.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eszopiclone use was associated with a cost of $US497." | 2.73 | Cost effectiveness of long-term treatment with eszopiclone for primary insomnia in adults: a decision analytical model. ( Botteman, MF; Foley, DJ; Ozminkowski, RJ; Pashos, CL; Schaefer, K; Wang, S, 2007) |
| " The validated method was successfully employed for a comparative bioavailability study after oral administration of 7." | 2.73 | HPLC-ESI-MS/MS validated method for simultaneous quantification of zopiclone and its metabolites, N-desmethyl zopiclone and zopiclone-N-oxide in human plasma. ( Jangid, AG; Mistri, HN; Pudage, A; Shrivastav, P, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nordström, P | 1 |
| Nordström, A | 1 |
| Eliassen, E | 1 |
| Kristoffersen, L | 1 |
| Hjelmeland, K | 1 |
| Gustavsen, I | 1 |
| Bernard, JP | 1 |
| Mørland, J | 1 |
| Naguib, IA | 1 |
| Abdelrahman, MM | 1 |
| El Ghobashy, MR | 1 |
| Ali, NA | 1 |
| Salomone, A | 1 |
| Gerace, E | 1 |
| Brizio, P | 1 |
| Gennaro, MC | 1 |
| Vincenti, M | 1 |
| Nirogi, RV | 1 |
| Kandikere, VN | 1 |
| Mudigonda, K | 1 |
| Gunnar, T | 1 |
| Ariniemi, K | 1 |
| Lillsunde, P | 1 |
| Botteman, MF | 1 |
| Ozminkowski, RJ | 1 |
| Wang, S | 1 |
| Pashos, CL | 1 |
| Schaefer, K | 1 |
| Foley, DJ | 1 |
| Mistri, HN | 1 |
| Jangid, AG | 1 |
| Pudage, A | 1 |
| Shrivastav, P | 1 |
| Foster, RT | 1 |
| Caillé, G | 1 |
| Ngoc, AH | 1 |
| Lemko, CH | 1 |
| Kherani, R | 1 |
| Pasutto, FM | 1 |
| Mannaert, E | 2 |
| Daenens, P | 2 |
| Hempel, G | 1 |
| Blaschke, G | 1 |
| Tytgat, J | 1 |
3 trials available for zopiclone and Sensitivity and Specificity
| Article | Year |
|---|---|
Can a simple clinical test detect impairment of zopiclone and alcohol? - A randomized controlled trial.
Topics: Azabicyclo Compounds; Blood Alcohol Content; Double-Blind Method; Driving Under the Influence; Foren | 2015 |
Cost effectiveness of long-term treatment with eszopiclone for primary insomnia in adults: a decision analytical model.
Topics: Adult; Aged; Azabicyclo Compounds; Costs and Cost Analysis; Female; Humans; Hypnotics and Sedatives; | 2007 |
HPLC-ESI-MS/MS validated method for simultaneous quantification of zopiclone and its metabolites, N-desmethyl zopiclone and zopiclone-N-oxide in human plasma.
Topics: Azabicyclo Compounds; Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; | 2008 |
10 other studies available for zopiclone and Sensitivity and Specificity
| Article | Year |
|---|---|
Use of short-acting and long-acting hypnotics and the risk of fracture: a critical analysis of associations in a nationwide cohort.
Topics: Acetamides; Aged; Aged, 80 and over; Azabicyclo Compounds; Case-Control Studies; Cohort Studies; Fem | 2019 |
Quantitative determination of zopiclone and zolpidem in whole blood by liquid-liquid extraction and UHPLC-MS/MS.
Topics: Autopsy; Azabicyclo Compounds; Chromatography, High Pressure Liquid; Forensic Medicine; Humans; Hypn | 2014 |
HPTLC Method for Quantitative Determination of Zopiclone and Its Impurity.
Topics: Azabicyclo Compounds; Chromatography, Thin Layer; Drug Contamination; Linear Models; Piperazines; Py | 2015 |
A fast liquid chromatography-tandem mass spectrometry method for determining benzodiazepines and analogues in urine. Validation and application to real cases of forensic interest.
Topics: Azabicyclo Compounds; Benzodiazepines; Chromatography, Liquid; Forensic Medicine; Humans; Hydrolysis | 2011 |
Quantitation of zopiclone and desmethylzopiclone in human plasma by high-performance liquid chromatography using fluorescence detection.
Topics: Azabicyclo Compounds; Chromatography, High Pressure Liquid; Drug Stability; Fluorescence; Humans; Pi | 2006 |
Fast gas chromatography-negative-ion chemical ionization mass spectrometry with microscale volume sample preparation for the determination of benzodiazepines and alpha-hydroxy metabolites, zaleplon and zopiclone in whole blood.
Topics: Acetamides; Azabicyclo Compounds; Benzodiazepines; Blood Chemical Analysis; Gas Chromatography-Mass | 2006 |
Stereospecific high-performance liquid chromatographic assay of zopiclone in human plasma.
Topics: Azabicyclo Compounds; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Hypn | 1994 |
Development of a radioimmunoassay for the determination of N-desmethylzopiclone in urine.
Topics: Animals; Antibody Specificity; Azabicyclo Compounds; Emergencies; Forensic Medicine; Humans; Hypnoti | 1994 |
Enantioselective determination of zopiclone and its metabolites in urine by capillary electrophoresis.
Topics: Azabicyclo Compounds; Electrophoresis, Capillary; Humans; Hypnotics and Sedatives; Piperazines; Repr | 1996 |
Development of a stereospecific radioimmunoassay for the analysis of zopiclone and metabolites in urine.
Topics: Animals; Antibody Specificity; Azabicyclo Compounds; Cross Reactions; Humans; Hypnotics and Sedative | 1996 |