A UDP-glucose 4-epimerase that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q14376]
EC 5.1.3.2;
Galactowaldenase;
UDP-N-acetylgalactosamine 4-epimerase;
UDP-GalNAc 4-epimerase;
UDP-N-acetylglucosamine 4-epimerase;
UDP-GlcNAc 4-epimerase;
5.1.3.7;
UDP-galactose 4-epimerase
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| ebselen | Homo sapiens (human) | IC50 | 0.0140 | 1 | 1 |
| ethacrynic acid | Homo sapiens (human) | IC50 | 14.0000 | 1 | 1 |
| haloprogin | Homo sapiens (human) | IC50 | 0.5000 | 1 | 1 |
| diethylstilbestrol | Homo sapiens (human) | IC50 | 75.0000 | 1 | 1 |
| psammaplin a | Homo sapiens (human) | IC50 | 3.6000 | 1 | 1 |
This protein enables 4 target(s):
| Target | Category | Definition |
|---|---|---|
| UDP-N-acetylglucosamine 4-epimerase activity | molecular function | Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine. [EC:5.1.3.7] |
| UDP-glucose 4-epimerase activity | molecular function | Catalysis of the reaction: UDP-glucose = UDP-galactose. [EC:5.1.3.2] |
| identical protein binding | molecular function | Binding to an identical protein or proteins. [GOC:jl] |
| protein homodimerization activity | molecular function | Binding to an identical protein to form a homodimer. [GOC:jl] |
This protein is located in 1 target(s):
| Target | Category | Definition |
|---|---|---|
| cytosol | cellular component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
This protein is active in 1 target(s):
| Target | Category | Definition |
|---|---|---|
| cytosol | cellular component | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl] |
This protein is involved in 2 target(s):
| Target | Category | Definition |
|---|---|---|
| galactose catabolic process | biological process | The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose. [ISBN:0198506732] |
| galactose catabolic process via UDP-galactose | biological process | The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose. [GOC:mah, MetaCyc:PWY-3821] |