Proteins > caspase-1 isoform alpha precursor
Page last updated: 2024-08-07 12:40:10

caspase-1 isoform alpha precursor

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (252)

Drugs with Potency Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
4-aminophenolHomo sapiens (human)Potency31.622810
4-amino-1,8-naphthalimideHomo sapiens (human)Potency7.943310
p-chloromercuribenzoic acidHomo sapiens (human)Potency7.506020
amsacrineHomo sapiens (human)Potency15.848910
bithionolHomo sapiens (human)Potency39.810710
clofoctolHomo sapiens (human)Potency25.118910
dephostatinHomo sapiens (human)Potency31.622810
dichlorophenHomo sapiens (human)Potency39.810710
dipyridamoleHomo sapiens (human)Potency4.496510
ellipticineHomo sapiens (human)Potency12.589310
gossypolHomo sapiens (human)Potency18.854120
harmalineHomo sapiens (human)Potency12.589310
harmalolHomo sapiens (human)Potency15.848910
amrinoneHomo sapiens (human)Potency29.881610
jugloneHomo sapiens (human)Potency19.952610
mesalamineHomo sapiens (human)Potency9.449410
piromidic acidHomo sapiens (human)Potency25.118910
propidiumHomo sapiens (human)Potency2.511910
triamtereneHomo sapiens (human)Potency16.989310
reserpineHomo sapiens (human)Potency7.943310
2,4-dichlorobenzoic acidHomo sapiens (human)Potency39.810710
9,10-dimethyl-1,2-benzanthraceneHomo sapiens (human)Potency31.622810
primaquine phosphateHomo sapiens (human)Potency31.622810
colchicineHomo sapiens (human)Potency39.810710
quinacrine monohydrochlorideHomo sapiens (human)Potency5.011910
trichloroethyleneHomo sapiens (human)Potency39.810710
tetrabromobisphenol aHomo sapiens (human)Potency39.810710
benzanthroneHomo sapiens (human)Potency15.848910
7,8-dimethyl-10-[(2R,3R,4S)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4-dioneHomo sapiens (human)Potency10.000010
acriflavine chlorideHomo sapiens (human)Potency3.981110
aminacrineHomo sapiens (human)Potency15.848910
xanthoneHomo sapiens (human)Potency25.118910
uvitex swnHomo sapiens (human)Potency12.589310
1,2-diaminobenzeneHomo sapiens (human)Potency39.810710
2,4-diaminotolueneHomo sapiens (human)Potency31.622810
cyclohexanone oximeHomo sapiens (human)Potency39.810710
3-phenylenediamineHomo sapiens (human)Potency39.810710
suramin sodiumHomo sapiens (human)Potency39.810710
pyrazolanthroneHomo sapiens (human)Potency3.981110
amprolium hydrochlorideHomo sapiens (human)Potency39.810710
benzo(b)fluorantheneHomo sapiens (human)Potency31.622810
benzo(k)fluorantheneHomo sapiens (human)Potency12.589310
rheinHomo sapiens (human)Potency35.716820
plumbaginHomo sapiens (human)Potency22.106010
ninhydrinHomo sapiens (human)Potency39.810710
6-aminoquinolineHomo sapiens (human)Potency25.118910
2-anthramineHomo sapiens (human)Potency31.622810
methyl isocyanateHomo sapiens (human)Potency39.810710
ethidium bromideHomo sapiens (human)Potency6.477610
popopHomo sapiens (human)Potency6.309610
4-amino-2-hydroxytolueneHomo sapiens (human)Potency39.810710
coralyneHomo sapiens (human)Potency3.162310
flupirtineHomo sapiens (human)Potency12.589310
topotecan hydrochlorideHomo sapiens (human)Potency6.581210
toxoflavinHomo sapiens (human)Potency7.292320
nonoxynol-9Homo sapiens (human)Potency31.622810
1-ethyl-2-benzo[cd]indoloneHomo sapiens (human)Potency25.118910
7-amino-4-methylcoumarinHomo sapiens (human)Potency25.118910
coumarin 7Homo sapiens (human)Potency0.158510
harmol hydrochlorideHomo sapiens (human)Potency25.118910
quercetin 5,7,3',4'-tetramethyl etherHomo sapiens (human)Potency31.622810
10-hydroxycamptothecinHomo sapiens (human)Potency15.848910
oxoglaucineHomo sapiens (human)Potency39.810710
7-amino-4-trifluoromethylcoumarinHomo sapiens (human)Potency3.981110
6-(6-methoxy-1,3-benzodioxol-5-yl)-7-furo[3,2-g][1]benzopyranoneHomo sapiens (human)Potency31.622810
methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylateHomo sapiens (human)Potency19.952610
2,2'-pyridylisatogen tosylateHomo sapiens (human)Potency31.622810
furamidineHomo sapiens (human)Potency3.981110
methotrexateHomo sapiens (human)Potency15.848910
isoteolinHomo sapiens (human)Potency31.622820
harmalol hydrochlorideHomo sapiens (human)Potency3.981110
raubasineHomo sapiens (human)Potency25.118910
nsc 95397Homo sapiens (human)Potency15.848910
3-amino-4,6-dimethyl-2-thieno[2,3-b]pyridinecarboxylic acid ethyl esterHomo sapiens (human)Potency39.810710
nsc 663284Homo sapiens (human)Potency4.410820
nsc668394Homo sapiens (human)Potency5.011910
1-methyl-6-methoxy-dihydro-beta-carbolineHomo sapiens (human)Potency15.848910
nsc354961Homo sapiens (human)Potency3.162310
arachidonic acidHomo sapiens (human)Potency31.622810
dactinomycinHomo sapiens (human)Potency31.622810
riboflavinHomo sapiens (human)Potency31.622810
2-Methylindole-3-acetic acidHomo sapiens (human)Potency31.622810
2-amino-3-cyano-5,6,7,8-tetrahydroquinoline-4-carboxylic acid methyl esterHomo sapiens (human)Potency25.118910
6-amino-2-methyl-8-phenyl-1,6,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrileHomo sapiens (human)Potency15.848910
3-[(1-cyclopentyl-5-tetrazolyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methyl]-7-methoxy-1H-quinolin-2-oneHomo sapiens (human)Potency25.118910
2-imino-N,8-dimethyl-5-oxo-1-propan-2-yl-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarboxamideHomo sapiens (human)Potency1.258910
LSM-19079Homo sapiens (human)Potency12.589310
3-amino-N-cyclopentyl-6-thiophen-2-yl-2-thieno[2,3-b]pyridinecarboxamideHomo sapiens (human)Potency15.848910
5-(1,3-benzodioxol-5-yl)-N-(2-furanylmethyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamideHomo sapiens (human)Potency31.622810
5-(diethylsulfamoyl)-3-hydroxy-2-naphthalenecarboxylic acidHomo sapiens (human)Potency25.118910
3-[[1,3-benzodioxol-5-ylmethyl-[(1-cyclopentyl-5-tetrazolyl)methyl]amino]methyl]-6-ethyl-1H-quinolin-2-oneHomo sapiens (human)Potency31.622810
11-[2-(4-morpholinyl)ethylamino]-7,8,9,10-tetrahydrobenzimidazolo[1,2-b]isoquinoline-6-carbonitrileHomo sapiens (human)Potency10.000010
3-[[[1-[1-(2-furanylmethyl)-5-tetrazolyl]-2-methylpropyl]-(2-oxolanylmethyl)amino]methyl]-8-methyl-1H-quinolin-2-oneHomo sapiens (human)Potency25.118910
3-(benzenesulfonyl)-2-imino-1-(2-oxolanylmethyl)-5-dipyrido[1,2-d-3',4'-f]pyrimidinoneHomo sapiens (human)Potency12.589310
6-ethoxy-3-[[2-oxolanylmethyl-[[1-(2-phenylethyl)-5-tetrazolyl]methyl]amino]methyl]-1H-quinolin-2-oneHomo sapiens (human)Potency31.622810
3-[1-azepanyl-[1-(phenylmethyl)-5-tetrazolyl]methyl]-7-methoxy-1H-quinolin-2-oneHomo sapiens (human)Potency25.118910
3-[[[1-(2-furanylmethyl)-5-tetrazolyl]methyl-[(2-methoxyphenyl)methyl]amino]methyl]-6-methyl-1H-quinolin-2-oneHomo sapiens (human)Potency31.622810
7-[[1-(2-oxolanylmethyl)-5-tetrazolyl]-(1-pyrrolidinyl)methyl]-5H-[1,3]dioxolo[4,5-g]quinolin-6-oneHomo sapiens (human)Potency31.622810
N-[2,5-dimethoxy-4-[[oxo(thiophen-2-yl)methyl]amino]phenyl]-2-furancarboxamideHomo sapiens (human)Potency31.622810
9,10-dimethoxy-2,4,6,7-tetrahydro-[1,3]oxazino[4,3-a]isoquinoline-1-carbonitrileHomo sapiens (human)Potency31.622810
6-methyl-2-[4-[oxo(thiophen-2-yl)methyl]-1-piperazinyl]-3-quinolinecarbonitrileHomo sapiens (human)Potency31.622810
[5-(2-furanyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinyl]-[4-(2-pyridinyl)-1-piperazinyl]methanoneHomo sapiens (human)Potency31.622810
5,7-dimethyl-2-(1-pyrrolidinyl)-3-quinolinecarbonitrileHomo sapiens (human)Potency25.118910
3-[[[1-[(4-fluorophenyl)methyl]-5-tetrazolyl]methyl-(2-hydroxyethyl)amino]methyl]-7-methyl-1H-quinolin-2-oneHomo sapiens (human)Potency31.622810
2-[[2-(1-azepanyl)-2-oxoethyl]thio]-6-methoxy-3-quinolinecarbonitrileHomo sapiens (human)Potency25.118910
3-(2,5-dimethyl-1-pyrrolyl)-4-methylanilineHomo sapiens (human)Potency25.118910
8-[2-(4-methoxyphenyl)-5-phenyl-7-pyrazolo[1,5-a]pyrimidinyl]-1,4-dioxa-8-azaspiro[4.5]decaneHomo sapiens (human)Potency25.118910
6-methoxy-3-[[[1-(2-methoxyethyl)-5-tetrazolyl]methyl-(3-pyridinylmethyl)amino]methyl]-1H-quinolin-2-oneHomo sapiens (human)Potency31.622810
1-(3-cyano-7-methoxy-2-quinolinyl)-4-piperidinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
3-[3,4-dihydro-1H-isoquinolin-2-yl-[1-(2-methylbutan-2-yl)-5-tetrazolyl]methyl]-7-methoxy-1H-quinolin-2-oneHomo sapiens (human)Potency12.589310
4-[3-(1,3-dioxo-2-isoindolyl)propylamino]-2-methylisoindole-1,3-dioneHomo sapiens (human)Potency25.118910
N-[(1,3-dimethyl-4-pyrazolyl)methyl]-5-(2-furanyl)-N-methyl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamideHomo sapiens (human)Potency31.622810
3-[3,4-dihydro-1H-isoquinolin-2-yl-[1-(2-oxolanylmethyl)-5-tetrazolyl]methyl]-6-methyl-1H-quinolin-2-oneHomo sapiens (human)Potency39.810710
5-(4-fluorophenyl)-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxylic acid methyl esterHomo sapiens (human)Potency39.810710
6-methoxy-3-[[2-oxolanylmethyl-[[1-(phenylmethyl)-5-tetrazolyl]methyl]amino]methyl]-1H-quinolin-2-oneHomo sapiens (human)Potency25.118910
3-[[cyclopentyl-[[1-[(4-methoxyphenyl)methyl]-5-tetrazolyl]methyl]amino]methyl]-7-methyl-1H-quinolin-2-oneHomo sapiens (human)Potency39.810710
5,8-dimethoxy-4-(4-methyl-1-piperazinyl)-2-(trifluoromethyl)quinolineHomo sapiens (human)Potency25.118910
N-(2,1,3-benzothiadiazol-4-yl)-3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarboxamideHomo sapiens (human)Potency25.118910
5-amino-2-(4-methylphenyl)isoindole-1,3-dioneHomo sapiens (human)Potency25.118910
4-amino-N5-[1-(2-furanyl)-2-(3-methylbutylamino)-2-oxoethyl]-N5-(2-methoxyphenyl)isothiazole-3,5-dicarboxamideHomo sapiens (human)Potency39.810710
(6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-[5-(2-furanyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinyl]methanoneHomo sapiens (human)Potency25.118910
6-methoxy-3-[[[1-(2-oxolanylmethyl)-5-tetrazolyl]methyl-(2-phenylethyl)amino]methyl]-1H-quinolin-2-oneHomo sapiens (human)Potency25.118910
4-chloro-N-[(7-oxo-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-8-yl)methyl]-N-(2-oxolanylmethyl)benzenesulfonamideHomo sapiens (human)Potency25.118910
2-[(7-methyl-4-oxo-3-phenyl-6,8-dihydro-5H-pyrido[2,3]thieno[2,4-b]pyrimidin-2-yl)thio]acetic acid methyl esterHomo sapiens (human)Potency10.000010
2-cyano-N-(2-furanylmethyl)-2-[3-(4-morpholinyl)-2-quinoxalinyl]acetamideHomo sapiens (human)Potency19.952610
LSM-27020Homo sapiens (human)Potency25.118910
2-cyano-2-[3-[4-(phenylmethyl)-1-piperazinyl]-2-quinoxalinyl]acetic acid 2-methoxyethyl esterHomo sapiens (human)Potency15.848910
N-ethyl-2-imino-10-methyl-1-[(4-methylphenyl)methyl]-5-oxo-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamideHomo sapiens (human)Potency1.258910
5-(2,4-dimethoxyphenyl)-7-(3,4-dimethoxyphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidineHomo sapiens (human)Potency25.118910
3-methyl-N-(1-propyl-3-pyrazolo[3,4-b]quinolinyl)butanamideHomo sapiens (human)Potency19.952610
LSM-32147Homo sapiens (human)Potency31.622810
2-cyano-2-[3-(4-morpholinyl)-2-quinoxalinyl]acetic acid hexyl esterHomo sapiens (human)Potency25.118910
2-[2-(dimethylamino)ethylthio]-6,6-dimethyl-5,8-dihydropyrano[4,5]thieno[1,2-c]pyrimidin-4-amineHomo sapiens (human)Potency19.952610
3-[[2-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-1-oxoethyl]amino]-6-methyl-1H-indole-2-carboxylic acid methyl esterHomo sapiens (human)Potency39.810710
N-(1,8-dimethyl-3-pyrazolo[3,4-b]quinolinyl)propanamideHomo sapiens (human)Potency12.589310
2-(3-methylphenyl)sulfonyl-2-[3-(1-pyrrolidinyl)-2-quinoxalinyl]acetonitrileHomo sapiens (human)Potency15.848910
N-(1-ethyl-7-methyl-3-pyrazolo[3,4-b]quinolinyl)-2-furancarboxamideHomo sapiens (human)Potency15.848910
1-(thiophen-2-ylmethyl)-3-thiophen-2-ylsulfonyl-2-pyrrolo[3,2-b]quinoxalinamineHomo sapiens (human)Potency19.952610
N-(1,7-dimethyl-3-pyrazolo[3,4-b]quinolinyl)acetamideHomo sapiens (human)Potency15.848910
LSM-32980Homo sapiens (human)Potency15.848910
7-methyl-3-(3-methylbutylamino)-1-(1-pyrrolidinyl)-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrileHomo sapiens (human)Potency19.952610
5-(3-methoxyphenyl)-N-(2-oxolanylmethyl)-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxamideHomo sapiens (human)Potency25.118910
6-amino-1-(4-fluorophenyl)-3-methyl-4-thiophen-2-yl-5-pyrazolo[3,4-b]pyridinecarbonitrileHomo sapiens (human)Potency31.622810
1-(4-methylphenyl)spiro[1,3-diazinane-5,4'-2,3,3a,5-tetrahydro-1H-pyrrolo[1,2-a]quinoline]-2,4,6-trioneHomo sapiens (human)Potency31.622810
8-[[4-(4-fluorophenyl)-1-piperazinyl]methyl]-1,3-dimethyl-7-[2-(4-morpholinyl)ethyl]purine-2,6-dioneHomo sapiens (human)Potency15.848910
5-(4-methoxyphenyl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylic acidHomo sapiens (human)Potency31.622810
chlorprothixeneHomo sapiens (human)Potency25.118910
2-[(3-methyl-6-oxo-7,8,9,10-tetrahydrobenzo[c][1]benzopyran-1-yl)oxy]acetic acid propan-2-yl esterHomo sapiens (human)Potency1.258910
N,N-diethyl-2-oxo-1H-benzo[cd]indole-6-sulfonamideHomo sapiens (human)Potency25.118910
6-methyl-4-(trifluoromethyl)-7,8,9,10-tetrahydropyrano[2,3-f]quinolin-2-oneHomo sapiens (human)Potency0.501210
N-[3-chloro-4-(1-pyrrolidinyl)phenyl]-2-furancarboxamideHomo sapiens (human)Potency31.622810
4-[(6-methoxy-2-naphthalenyl)sulfonyl]morpholineHomo sapiens (human)Potency39.810710
6-(4-morpholinyl)naphthalene-2,3-dicarbonitrileHomo sapiens (human)Potency25.118910
3-(5-methoxy-2,2-dimethyl-1-benzopyran-8-yl)-3-oxopropanoic acidHomo sapiens (human)Potency25.118910
1-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-2-benzo[cd]indoloneHomo sapiens (human)Potency31.622810
5-[2-(6-hydroxy-3-methyl-2-benzofuranyl)-2-oxoethyl]-2-furancarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
2-[[oxo(thiophen-2-yl)methyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid propan-2-yl esterHomo sapiens (human)Potency25.118910
4-(1,3-benzothiazol-2-yl)-N-phenyl-1-piperazinecarboxamideHomo sapiens (human)Potency31.622810
N-(2-ethylphenyl)-2-methoxy-5-methylbenzenesulfonamideHomo sapiens (human)Potency15.848910
curcuminHomo sapiens (human)Potency23.735810
4-[[[2,3-bis(2-pyridinyl)-6-quinoxalinyl]amino]-oxomethyl]-1-piperazinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
2-fluoro-N-[4-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]phenyl]benzamideHomo sapiens (human)Potency39.810710
N-[4-[4-[(2-methylphenyl)-oxomethyl]-1-piperazinyl]phenyl]propanamideHomo sapiens (human)Potency25.118910
7-(difluoromethyl)-N-(5-methyl-3-isoxazolyl)-5-(4-methylphenyl)-3-pyrazolo[1,5-a]pyrimidinecarboxamideHomo sapiens (human)Potency19.952610
1-methyl-2-oxo-N-(2-pyridinyl)-6-benzo[cd]indolesulfonamideHomo sapiens (human)Potency31.622810
N-(2-furanylmethyl)-5-(4-methoxyphenyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamideHomo sapiens (human)Potency25.118910
N-(2-furanylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamideHomo sapiens (human)Potency25.118910
ym-90709Homo sapiens (human)Potency31.622810
3,5-dimethyl-N-[2-(methylthio)phenyl]-4-isoxazolecarboxamideHomo sapiens (human)Potency12.589310
2-[[2-(3,4-dimethylanilino)-2-oxoethyl]thio]acetamideHomo sapiens (human)Potency15.848910
N-(2-furanylmethyl)-2-imino-5-oxo-1-(2-phenylethyl)-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarboxamideHomo sapiens (human)Potency10.000010
3-phenyl-5-[[[4-phenyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]-1,2,4-oxadiazoleHomo sapiens (human)Potency25.118910
4-[[2-[(4-methyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)thio]-1-oxoethyl]amino]benzoic acid ethyl esterHomo sapiens (human)Potency25.118910
N-(6-ethoxy-1,3-benzothiazol-2-yl)-1,3-dimethyl-2-oxo-5-benzimidazolesulfonamideHomo sapiens (human)Potency12.589310
2-[[4-cyano-6,6,7-trimethyl-1-(4-morpholinyl)-5,8-dihydro-2,7-naphthyridin-3-yl]thio]acetic acid methyl esterHomo sapiens (human)Potency3.981110
4-(dimethylsulfamoyl)-N-(1-ethyl-2-oxo-6-benzo[cd]indolyl)benzamideHomo sapiens (human)Potency31.622810
zucapsaicinHomo sapiens (human)Potency15.848910
1-ethyl-N-[3-(4-morpholinyl)propyl]-2-oxo-6-benzo[cd]indolesulfonamideHomo sapiens (human)Potency15.848910
1-[2-(2-amino-3-cyano-1-pyrrolo[3,2-b]quinoxalinyl)ethyl]-3-phenylureaHomo sapiens (human)Potency15.848910
2-(2-furanyl)-5-methyl-6-(phenylmethyl)-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-oneHomo sapiens (human)Potency31.622810
4-(3,4-dimethoxyphenyl)-1-(2-methoxyethyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl esterHomo sapiens (human)Potency19.952610
3-methyl-6-thiophen-2-yl-4-isoxazolo[5,4-b]pyridinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
3-[1-(3-methoxypropyl)-5-thiophen-2-yl-2-pyrrolyl]propanoic acidHomo sapiens (human)Potency15.848910
1,4-dioxa-8-azaspiro[4.5]decan-8-yl-(5,7-diphenyl-2-pyrazolo[1,5-a]pyrimidinyl)methanoneHomo sapiens (human)Potency25.118910
4-amino-2-[[4-(1-azepanylsulfonyl)phenyl]-oxomethyl]isoindole-1,3-dioneHomo sapiens (human)Potency7.943310
3-[5-(2,5-dimethyl-1-phenyl-3-pyrrolyl)-1,3,4-oxadiazol-2-yl]-1-benzopyran-2-oneHomo sapiens (human)Potency15.848910
6-amino-4-(1,3-benzodioxol-5-yl)-5-cyano-2-methyl-4H-pyran-3-carboxylic acid 2-methoxyethyl esterHomo sapiens (human)Potency39.810710
N-(3-chloro-4-methylphenyl)-2-(3-oxo-2,4-dihydro-1H-quinoxalin-2-yl)acetamideHomo sapiens (human)Potency25.118910
2-(2-oxo-1-benzo[cd]indolyl)-N-(2-oxolanylmethyl)acetamideHomo sapiens (human)Potency25.118910
2-(2,5-dioxo-4-imidazolidinyl)-N-(1-naphthalenyl)acetamideHomo sapiens (human)Potency15.848910
N-[1-(4-chlorophenyl)sulfonyl-2-pyrrolidinyl]-4-methyl-1-piperazinecarboxamideHomo sapiens (human)Potency31.622810
2-cyano-N-(phenylmethyl)-2-[3-(1-pyrrolidinyl)-2-quinoxalinyl]acetamideHomo sapiens (human)Potency25.118910
2-(3,4-dimethoxyphenyl)-4-quinolinecarboxylic acid (2-oxo-3-oxolanyl) esterHomo sapiens (human)Potency31.622810
3-(4-methylphenyl)sulfonyl-1-(3-oxolanylmethyl)-2-pyrrolo[3,2-b]quinoxalinamineHomo sapiens (human)Potency19.952610
1,4-dimethoxy-10H-acridine-9-thioneHomo sapiens (human)Potency31.622810
7-(2-methoxyphenyl)-5-phenyl-1,7-dihydrotetrazolo[1,5-a]pyrimidineHomo sapiens (human)Potency39.810710
9-chloro-6-methylindolo[3,2-b]quinoxalineHomo sapiens (human)Potency31.622810
3-[2-[butyl(methyl)amino]ethyl]-6-(4-morpholinyl)-2-sulfanylidene-1H-quinazolin-4-oneHomo sapiens (human)Potency25.118910
4-[2-[(1'-acetyl-4-oxo-6-spiro[3,4-dihydro-2H-1-benzopyran-2,4'-piperidine]yl)oxy]-1-oxoethyl]-1-piperazinecarboxylic acid ethyl esterHomo sapiens (human)Potency31.622810
9-(4-methoxyphenyl)-3,3,6,6-tetramethyl-10-[2-(4-morpholinyl)ethyl]-4,5,7,9-tetrahydro-2H-acridine-1,8-dioneHomo sapiens (human)Potency15.848910
1-[[1-(2-methoxyanilino)-4-isoquinolinyl]-oxomethyl]-4-piperidinecarboxamideHomo sapiens (human)Potency31.622810
LSM-18934Homo sapiens (human)Potency25.118910
3-(2,5-dioxo-1-pyrrolidinyl)-N-(1-ethyl-2-oxo-6-benzo[cd]indolyl)benzamideHomo sapiens (human)Potency25.118910
2-amino-4-[5-methyl-2-(methylthio)-3-thiophenyl]-5-oxo-1-(3-pyridinyl)-4,6,7,8-tetrahydroquinoline-3-carbonitrileHomo sapiens (human)Potency31.622810
N-butyl-2-[[6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]acetamideHomo sapiens (human)Potency25.118910
2-chloro-6-[4-morpholinyl(oxo)methyl]-11-pyrido[2,1-b]quinazolinoneHomo sapiens (human)Potency15.848910
N-[2-(3,4-diethoxyphenyl)ethyl]-1-[6-(4-morpholinyl)-3-pyridazinyl]-4-piperidinecarboxamideHomo sapiens (human)Potency25.118910
5-(1-ethyl-3-methyl-4-pyrazolyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxylic acidHomo sapiens (human)Potency31.622810
4-[[7-[(4-fluorophenyl)methyl]-1,3-dimethyl-2,6-dioxo-8-purinyl]methyl]-1-piperazinecarboxylic acid ethyl esterHomo sapiens (human)Potency39.810710
sto 609Homo sapiens (human)Potency3.162310
1,3-dimethyl-8-[[methyl-(phenylmethyl)amino]methyl]-7-(2-methylpropyl)purine-2,6-dioneHomo sapiens (human)Potency39.810710
N-(2-furanylmethyl)-2-[[5-[(2-methyl-1H-indol-3-yl)methyl]-1,3,4-oxadiazol-2-yl]thio]acetamideHomo sapiens (human)Potency19.952610
2-methyl-5-[(4-phenyl-1-piperazinyl)-(3,4,5-trimethoxyphenyl)methyl]-6-thiazolo[3,2-b][1,2,4]triazololHomo sapiens (human)Potency39.810710
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acidHomo sapiens (human)Potency31.622810
fraxetinHomo sapiens (human)Potency23.735810
bilirubinHomo sapiens (human)Potency25.118910
scopoletinHomo sapiens (human)Potency3.662810
hymecromoneHomo sapiens (human)Potency12.589310
esculetinHomo sapiens (human)Potency7.506010
7-hydroxycoumarinHomo sapiens (human)Potency19.952610
yangoninHomo sapiens (human)Potency39.810710
3,7,4'-trihydroxyflavoneHomo sapiens (human)Potency15.848910
fisetinHomo sapiens (human)Potency20.483910
morinHomo sapiens (human)Potency39.810710
blebbistatinHomo sapiens (human)Potency31.622810
3-(3,4-dimethoxyphenyl)-5,7-dihydroxy-2-methyl-1-benzopyran-4-oneHomo sapiens (human)Potency25.118910
4-methyl-2,3-dihydro-1,4-benzothiazine-6-carboxylic acid methyl esterHomo sapiens (human)Potency31.622810
8-(diethylaminomethyl)-7-hydroxy-4-phenyl-1-benzopyran-2-oneHomo sapiens (human)Potency25.118910
irl 2500Homo sapiens (human)Potency31.622810
ly 320135Homo sapiens (human)Potency25.118910
6,7-dihydroxyflavoneHomo sapiens (human)Potency19.952610
5,7-dihydroxy-4-methylcoumarinHomo sapiens (human)Potency31.622810
7-hydroxy-4-phenyl-8-(1-piperidinylmethyl)-1-benzopyran-2-oneHomo sapiens (human)Potency3.162310
norstictic acidHomo sapiens (human)Potency6.309610
2-(5,7-dihydroxy-4-methyl-2-oxo-1-benzopyran-3-yl)acetic acid ethyl esterHomo sapiens (human)Potency15.848910
6-ethyl-7-hydroxy-4-[[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-1-benzopyran-2-oneHomo sapiens (human)Potency12.589310
7-hydroxy-6-(4-morpholinylmethyl)-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-4-oneHomo sapiens (human)Potency25.118910
3-(1-benzimidazolyl)-6-ethyl-7-hydroxy-1-benzopyran-4-oneHomo sapiens (human)Potency25.118910
3,7-dihydroxyflavoneHomo sapiens (human)Potency25.118910
papaverolineHomo sapiens (human)Potency3.981110
n'-((1e)-(4-(diethylamino)phenyl)methylene)-4-hydroxybenzohydrazideHomo sapiens (human)Potency31.622810
7-hydroxy-2-n,n-dipropylaminotetralin, (r)-isomerHomo sapiens (human)Potency39.810710
bvt.948Homo sapiens (human)Potency8.285220
LSM-6455Homo sapiens (human)Potency25.118910
phenylmercuric acetateHomo sapiens (human)Potency3.162310
(3S)-3-[[[(2S)-1-[(2S)-2-[[(4-amino-3-chlorophenyl)-oxomethyl]amino]-3,3-dimethyl-1-oxobutyl]-2-pyrrolidinyl]-oxomethyl]amino]-3-cyanopropanoic acidHomo sapiens (human)Potency0.000310
antimycinHomo sapiens (human)Potency39.810710
sepiapterinHomo sapiens (human)Potency15.848910
hemateinHomo sapiens (human)Potency39.810710
7-hydroxyquinolineHomo sapiens (human)Potency15.848910

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
perhexiline maleateHomo sapiens (human)IC5015.900010
dithiazanine iodideHomo sapiens (human)IC50100.000010