glyburide has been researched along with Sensitivity and Specificity in 42 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydrogen sulfide (H(2)S) is an endogenous gaseous mediator of mucosal defense with antiinflammatory effects that promote ulcer healing." | 5.35 | Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats. ( Dicay, M; Martin, GR; McKnight, W; Vong, L; Wallace, JL, 2009) |
| " We examined KATP channel modulation in renal ischemia-reperfusion injury (IRI), using an isolated perfused rat kidney (IPRK) model, in control, IRI, IRI+200 microM diazoxide (a KATP opener), IRI + 10 microM glibenclamide (a KATP blocker) and IRI + 200 microM diazoxide + 10 microM glibenclamide groups." | 3.72 | ATP-dependent K+ channels in renal ischemia reperfusion injury. ( Endre, ZH; Gobé, GC; Rahgozar, M; Willgoss, DA, 2003) |
| "Metformin was the antidiabetic drug at the highest concentration in wastewater and surface water (up to 253 ng L(-1) and 104 ng L(-1), respectively)." | 1.38 | High-performance liquid chromatography quadrupole time-of-flight mass spectrometry method for the analysis of antidiabetic drugs in aqueous environmental samples. ( Alonso, E; Aparicio, I; Buchberger, W; Martín, J; Santos, JL, 2012) |
| " Thus, the proposed method is simple and suitable for the simultaneous analysis of active ingredients in dosage forms and human serum." | 1.37 | Simultaneous determination of gliquidone, pioglitazone hydrochloride, and verapamil in formulation and human serum by RP-HPLC. ( Arayne, MS; Mirza, AZ; Sultana, N, 2011) |
| "Hydrogen sulfide (H(2)S) is an endogenous gaseous mediator of mucosal defense with antiinflammatory effects that promote ulcer healing." | 1.35 | Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats. ( Dicay, M; Martin, GR; McKnight, W; Vong, L; Wallace, JL, 2009) |
| "Glyburide was detected at 254 nm, with a total run time of 7 min per sample." | 1.35 | A simple and rapid HPLC method for the detection of glyburide in plasma original research communication (analytical). ( Aleksa, K; Gedeon, C; Kapur, B; Koren, G, 2008) |
| " The simultaneous determination of these analytes is important for the routine monitoring of diabetic patients who take combination medications and for studying the pharmacokinetics of the combined dosage forms." | 1.33 | The development and validation of liquid chromatography method for the simultaneous determination of metformin and glipizide, gliclazide, glibenclamide or glimperide in plasma. ( Aburuz, S; McElnay, J; Millership, J, 2005) |
| "Hypoglycemia was defined as blood glucose (BG) concentration < 60 mg/dl." | 1.30 | Prospective multicenter study of sulfonylurea ingestion in children. ( Anderson, BD; Anderson, DL; Fenn, J; Gorman, SE; Krenzelok, EP; Muir, SJ; Rodgers, GC; Rose, SR; Spiller, HA; Villalobos, D, 1997) |
| "Treatment with glyburide, pinacidil or hydralazine did not alter L-type calcium channels, assessed by [3H]PN 200 110 binding, in cardiac and brain membranes or small size Ca(2+)-activated K+ channels in brain assessed by [125I]apamin binding." | 1.28 | Regulation of ATP-sensitive K+ channels by chronic glyburide and pinacidil administration. ( Gopalakrishnan, M; Triggle, DJ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (42.86) | 18.2507 |
| 2000's | 19 (45.24) | 29.6817 |
| 2010's | 5 (11.90) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Zhang, X | 1 |
| Wang, X | 1 |
| Vernikovskaya, DI | 1 |
| Fokina, VM | 1 |
| Nanovskaya, TN | 1 |
| Hankins, GD | 1 |
| Ahmed, MS | 1 |
| Wallace, JL | 1 |
| Vong, L | 1 |
| McKnight, W | 1 |
| Dicay, M | 1 |
| Martin, GR | 1 |
| Hehir, MP | 1 |
| Moynihan, AT | 1 |
| Morrison, JJ | 1 |
| Arayne, MS | 1 |
| Sultana, N | 1 |
| Mirza, AZ | 1 |
| Valdivieso, ÁG | 1 |
| Marín, MC | 1 |
| Clauzure, M | 1 |
| Santa-Coloma, TA | 1 |
| Martín, J | 1 |
| Buchberger, W | 1 |
| Santos, JL | 1 |
| Alonso, E | 1 |
| Aparicio, I | 1 |
| Zhao, KS | 1 |
| Huang, X | 1 |
| Liu, J | 1 |
| Huang, Q | 1 |
| Jin, C | 1 |
| Jiang, Y | 1 |
| Jin, J | 1 |
| Zhao, G | 1 |
| Reddy, MM | 1 |
| Quinton, PM | 1 |
| Hamilton, KL | 1 |
| Butt, AG | 1 |
| Cheng, S | 1 |
| Carter, DJ | 1 |
| Ribalet, B | 1 |
| John, SA | 1 |
| Weiss, JN | 1 |
| Rahgozar, M | 1 |
| Willgoss, DA | 1 |
| Gobé, GC | 1 |
| Endre, ZH | 1 |
| Radi, A | 1 |
| Aburuz, S | 1 |
| Millership, J | 1 |
| McElnay, J | 1 |
| Lai, EP | 1 |
| Feng, SY | 1 |
| Albu, F | 2 |
| Georgiţă, C | 2 |
| David, V | 2 |
| Medvedovici, A | 2 |
| Mistri, HN | 1 |
| Jangid, AG | 1 |
| Shrivastav, PS | 1 |
| Chakradhar, L | 1 |
| Kallem, R | 1 |
| Karthik, A | 1 |
| Sundari, BT | 1 |
| Ramesh, S | 1 |
| Mullangi, R | 1 |
| Srinivas, NR | 1 |
| Naraharisetti, SB | 1 |
| Kirby, BJ | 1 |
| Hebert, MF | 1 |
| Easterling, TR | 1 |
| Unadkat, JD | 1 |
| Gedeon, C | 1 |
| Kapur, B | 1 |
| Aleksa, K | 1 |
| Koren, G | 1 |
| Asano, M | 1 |
| Masuzawa-Ito, K | 1 |
| Matsuda, T | 1 |
| Suzuki, Y | 1 |
| Oyama, H | 1 |
| Shibuya, M | 1 |
| Sugita, K | 1 |
| Sener, A | 1 |
| Akkan, AG | 1 |
| Malaisse, WJ | 1 |
| Lorrain, J | 1 |
| Angel, I | 1 |
| Eon, MT | 1 |
| Oblin, A | 1 |
| Langer, SZ | 1 |
| Guillemare, E | 1 |
| Lazdunski, M | 1 |
| Honoré, E | 1 |
| Fozard, JR | 1 |
| Carruthers, AM | 1 |
| Findlay, I | 1 |
| Hong, KW | 1 |
| Park, MG | 1 |
| Shin, YW | 1 |
| Rhim, BY | 1 |
| Ko, KH | 1 |
| Simonsen, U | 1 |
| Prieto, D | 1 |
| Sánez de Tejada, I | 1 |
| García-Sacristán, A | 1 |
| Hide, EJ | 1 |
| Piper, J | 1 |
| Thiemermann, C | 1 |
| Yamanouchi, T | 1 |
| Ogata, N | 1 |
| Tagaya, T | 1 |
| Kawasaki, T | 1 |
| Sekino, N | 1 |
| Funato, H | 1 |
| Akaoka, L | 1 |
| Miyashita, H | 1 |
| Zhang, HL | 1 |
| Bolton, TB | 1 |
| Valdes Santurio, JR | 1 |
| González Porto, E | 1 |
| Spiller, HA | 1 |
| Villalobos, D | 1 |
| Krenzelok, EP | 1 |
| Anderson, BD | 1 |
| Gorman, SE | 1 |
| Rose, SR | 1 |
| Fenn, J | 1 |
| Anderson, DL | 1 |
| Muir, SJ | 1 |
| Rodgers, GC | 1 |
| Boels, PJ | 1 |
| Gao, B | 1 |
| Deutsch, J | 1 |
| Haworth, SG | 1 |
| Nishiyama, M | 1 |
| Okamoto, H | 1 |
| Watanabe, T | 1 |
| Hori, T | 1 |
| Sasaki, T | 1 |
| Kirino, T | 1 |
| Shimizu, T | 1 |
| Taverna, MJ | 1 |
| Pacher, N | 1 |
| Bruzzo, F | 1 |
| Slama, G | 1 |
| Selam, JL | 1 |
| Hsieh, S | 1 |
| Selinger, K | 1 |
| Fukuse, T | 1 |
| Hirata, T | 1 |
| Omasa, M | 1 |
| Wada, H | 1 |
| Judd, RL | 1 |
| Kunjathoor, VV | 1 |
| Pillai, UA | 1 |
| Ferguson, PW | 1 |
| Medon, PJ | 1 |
| Holzmann, S | 1 |
| Kukovetz, WR | 1 |
| Braida, C | 1 |
| Pöch, G | 1 |
| Gopalakrishnan, M | 1 |
| Triggle, DJ | 1 |
2 trials available for glyburide and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous assay of metformin and glibenclamide in human plasma based on extraction-less sample preparation procedure and LC/(APCI)MS.
Topics: Adult; Chromatography, Liquid; Female; Glyburide; Humans; Hypoglycemic Agents; Male; Mass Spectromet | 2007 |
Clinical usefulness of serum 1,5-anhydroglucitol in monitoring glycaemic control.
Topics: Biomarkers; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Type 2; Drug Administration Schedule; Ev | 1996 |
40 other studies available for glyburide and Sensitivity and Specificity
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Quantitative determination of metformin, glyburide and its metabolites in plasma and urine of pregnant patients by LC-MS/MS.
Topics: Adult; Chromatography, High Pressure Liquid; Diabetes, Gestational; Female; Glyburide; Humans; Hypog | 2015 |
Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats.
Topics: Analysis of Variance; Animals; Biomarkers; Biopsy, Needle; Colitis; Cyclooxygenase 1; Cyclooxygenase | 2009 |
Relaxant effect of Levosimendan on human uterine contractility in vitro.
Topics: Case-Control Studies; Dose-Response Relationship, Drug; Female; Glyburide; Humans; Hydrazones; In Vi | 2010 |
Simultaneous determination of gliquidone, pioglitazone hydrochloride, and verapamil in formulation and human serum by RP-HPLC.
Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Glyburide; Humans; Linear Model | 2011 |
Measurement of cystic fibrosis transmembrane conductance regulator activity using fluorescence spectrophotometry.
Topics: Cells, Cultured; Chloride Channels; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regul | 2011 |
High-performance liquid chromatography quadrupole time-of-flight mass spectrometry method for the analysis of antidiabetic drugs in aqueous environmental samples.
Topics: Chromatography, High Pressure Liquid; Drinking Water; Glyburide; Hydrogen-Ion Concentration; Hypogly | 2012 |
New approach to treatment of shock--restitution of vasoreactivity.
Topics: Animals; Blood Pressure; Dimethyl Sulfoxide; Disease Models, Animal; Dopamine; Glyburide; Hemodynami | 2002 |
Effect of anion transport blockers on CFTR in the human sweat duct.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo | 2002 |
Methoxsalen stimulates electrogenic Cl- secretion in the mouse jejunum.
Topics: Animals; Barium; Bumetanide; Chlorine; Colforsin; Dose-Response Relationship, Drug; Glyburide; In Vi | 2002 |
Molecular basis for Kir6.2 channel inhibition by adenine nucleotides.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Amino Acids; Dose-Response Relationship, Drug; Glyburid | 2003 |
ATP-dependent K+ channels in renal ischemia reperfusion injury.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Cromakalim; Diazoxide; Disease Models, Animal; | 2003 |
Voltammetric study of glibenclamide at carbon paste and Sephadex-modified carbon paste electrodes.
Topics: Calibration; Carbon; Electrochemistry; Glyburide; Hypoglycemic Agents; Reproducibility of Results; S | 2004 |
The development and validation of liquid chromatography method for the simultaneous determination of metformin and glipizide, gliclazide, glibenclamide or glimperide in plasma.
Topics: Chromatography, High Pressure Liquid; Gliclazide; Glipizide; Glyburide; Humans; Hypoglycemic Agents; | 2005 |
Solid phase extraction--non-aqueous capillary electrophoresis for determination of metformin, phenformin and glyburide in human plasma.
Topics: Electrophoresis, Capillary; Glyburide; Humans; Hypoglycemic Agents; Metformin; Phenformin; Reference | 2006 |
Determination of glibenclamide in human plasma by liquid chromatography and atmospheric pressure chemical ionization/MS-MS detection.
Topics: Atmospheric Pressure; Glyburide; Humans; Hypoglycemic Agents; Mass Spectrometry; Reference Standards | 2007 |
Liquid chromatography tandem mass spectrometry method for simultaneous determination of antidiabetic drugs metformin and glyburide in human plasma.
Topics: Chromatography, High Pressure Liquid; Glyburide; Humans; Hypoglycemic Agents; Male; Metformin; Repro | 2007 |
A rapid and highly sensitive method for the determination of glimepiride in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry: application to a pre-clinical pharmacokinetic study.
Topics: Acetates; Acetonitriles; Administration, Oral; Animals; Chemical Fractionation; Chromatography, High | 2008 |
Validation of a sensitive LC-MS assay for quantification of glyburide and its metabolite 4-transhydroxy glyburide in plasma and urine: an OPRU Network study.
Topics: Chromatography, High Pressure Liquid; Diabetes, Gestational; Female; Glucuronidase; Glyburide; Human | 2007 |
A simple and rapid HPLC method for the detection of glyburide in plasma original research communication (analytical).
Topics: Chemical Fractionation; Chromatography, High Pressure Liquid; Diabetes, Gestational; Drug Monitoring | 2008 |
Functional role of charybdotoxin-sensitive K+ channels in the resting state of cerebral, coronary and mesenteric arteries of the dog.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Standardized procedure for the assay and identification of hypoglycemic sulfonylureas in human plasma.
Topics: Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Drug Monitoring; Forensic Medicine; | 1995 |
Inhibition of insulin release induced by galanin in the dog is not exclusively mediated by activation of ATP-sensitive K+ channels.
Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Diazoxide; Dioxa | 1993 |
Glibenclamide opens ATP-sensitive potassium channels in Xenopus oocyte follicular cells during metabolic stress.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Dinitrophenols; Drug Interactions; Electrophysiolo | 1995 |
The cardiovascular effects of selective adenosine A1 and A2 receptor agonists in the pithed rat: no role for glibenclamide-sensitive potassium channels.
Topics: Adenosine; Adrenergic alpha-Agonists; Angiotensin II; Animals; Benzopyrans; Blood Pressure; Cardiova | 1993 |
Sulphonylurea drugs no longer inhibit ATP-sensitive K+ channels during metabolic stress in cardiac muscle.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Ce | 1993 |
Effect of ouabain on relaxation induced by cromakalim in human and canine mesenteric arteries.
Topics: Adult; Animals; Benzopyrans; Cromakalim; Dogs; Female; Glyburide; Humans; Male; Mesenteric Arteries; | 1993 |
Involvement of nitric oxide in the non-adrenergic non-cholinergic neurotransmission of horse deep penile arteries: role of charybdotoxin-sensitive K(+)-channels.
Topics: Adrenergic Fibers; Animals; Arginine; Charybdotoxin; Cholinergic Fibers; Electric Stimulation; Endot | 1995 |
Endothelin-1-induced reduction of myocardial infarct size by activation of ATP-sensitive potassium channels in a rabbit model of myocardial ischaemia and reperfusion.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arterial Occlusive Diseases; Blood Pressure | 1995 |
Two types of ATP-sensitive potassium channels in rat portal vein smooth muscle cells.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cells, Cultured; Cromakalim; Glyburide; Guanidines; Ma | 1996 |
Determination of glibenclamide in human plasma by solid-phase extraction and high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Glyburide; Humans; Hypoglycemic Agents; Reference Standards; S | 1996 |
Prospective multicenter study of sulfonylurea ingestion in children.
Topics: Accidents; Administration, Oral; Blood Glucose; Body Weight; Child; Child, Preschool; Confidence Int | 1997 |
ATP-dependent K+ channel activation in isolated normal and hypertensive newborn and adult porcine pulmonary vessels.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Antihypertensive Agents; Cromakalim; Cyclooxygena | 1997 |
Endothelium is required for 12-hydroperoxyeicosatetraenoic acid-induced vasoconstriction.
Topics: Animals; Basilar Artery; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Glyb | 1998 |
Beta-cell function evaluated by HOMA as a predictor of secondary sulphonylurea failure in Type 2 diabetes.
Topics: Biomarkers; Blood Glucose; Calibration; Diabetes Mellitus, Type 2; Female; Glyburide; Glycated Hemog | 2001 |
High-throughput bioanalytical method using automated sample preparation and liquid chromatography-atmospheric pressure ionspray mass spectrometry for quantitative determination of glybenclamide in human serum.
Topics: Atmospheric Pressure; Automation; Chromatography, Liquid; Glyburide; Humans; Hypoglycemic Agents; Re | 2002 |
Effect of adenosine triphosphate-sensitive potassium channel openers on lung preservation.
Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Glyburide; Hypertension, Pulmonary; Lung; P | 2002 |
Effect of tolbutamide and glyburide on pyruvate kinase flux in isolated rat hepatocytes.
Topics: Animals; Bicarbonates; Carbon Radioisotopes; Glucose; Glyburide; Lactates; Liver; Male; Pyruvate Kin | 1992 |
Pharmacological interaction experiments differentiate between glibenclamide-sensitive K+ channels and cyclic GMP as components of vasodilation by nicorandil.
Topics: Animals; Benzopyrans; Cattle; Coronary Vessels; Cromakalim; Cyclic GMP; Drug Interactions; Glyburide | 1992 |
Regulation of ATP-sensitive K+ channels by chronic glyburide and pinacidil administration.
Topics: Adenosine Triphosphate; Animals; Apamin; Brain; Calcium; Calcium Channels; Glyburide; Guanidines; He | 1992 |