Page last updated: 2024-08-07 22:41:53

Gag-Pol polyprotein

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate RF/HAT3). [PRO:DAN, UniProtKB:P05959]

Synonyms

Pr160Gag-Pol

Research

Bioassay Publications (1)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Compounds (7)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
nelfinavirHuman immunodeficiency virus type 1 (RF/HAT ISOLATE)Ki0.028516
amprenavirHuman immunodeficiency virus type 1 (RF/HAT ISOLATE)Ki0.004816
lopinavirHuman immunodeficiency virus type 1 (RF/HAT ISOLATE)Ki0.001716
atazanavirHuman immunodeficiency virus type 1 (RF/HAT ISOLATE)Ki0.000616
ritonavirHuman immunodeficiency virus type 1 (RF/HAT ISOLATE)Ki0.006916
saquinavirHuman immunodeficiency virus type 1 (RF/HAT ISOLATE)Ki0.012716
indinavir sulfateHuman immunodeficiency virus type 1 (RF/HAT ISOLATE)Ki0.298016