dantrolene has been researched along with Sensitivity and Specificity in 3 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bifunctional dantrolene derivatives have been synthesized as probes for radioisotope-free photoaffinity labeling with the aim of elucidating the molecular mechanism of skeletal muscle contraction." | 3.73 | Design of dantrolene-derived probes for radioisotope-free photoaffinity labeling of proteins involved in the physiological Ca2+ release from sarcoplasmic reticulum of skeletal muscle. ( Aoyama, H; Endo, M; Hiramatsu, T; Hosoya, T; Ikemoto, T; Ohmae, T; Suzuki, M, 2005) |
| "The association of malignant hyperthermia-like reactions with other neuromuscular disorders requires the collaboration of several clinical disciplines to achieve a timely recognition of this still life-threatening disorder." | 2.42 | [Malignant hyperthermia]. ( Kress, HG; Zeitlhofer, J; Zimprich, F, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ragab, MA | 1 |
| Korany, MA | 1 |
| Galal, SM | 1 |
| Ahmed, AR | 1 |
| Zimprich, F | 1 |
| Kress, HG | 1 |
| Zeitlhofer, J | 1 |
| Hosoya, T | 1 |
| Hiramatsu, T | 1 |
| Ikemoto, T | 1 |
| Aoyama, H | 1 |
| Ohmae, T | 1 |
| Endo, M | 1 |
| Suzuki, M | 1 |
1 review available for dantrolene and Sensitivity and Specificity
| Article | Year |
|---|---|
[Malignant hyperthermia].
Topics: Adult; Biopsy; Child; Dantrolene; Humans; Injections, Intravenous; Malignant Hyperthermia; Muscle Co | 2003 |
2 other studies available for dantrolene and Sensitivity and Specificity
| Article | Year |
|---|---|
Voltammetric analysis of dantrolene and its active metabolite with indomethacin in rat plasma.
Topics: Animals; Calibration; Dantrolene; Electrochemistry; Electrodes; Indomethacin; Male; Polarography; Ra | 2019 |
Design of dantrolene-derived probes for radioisotope-free photoaffinity labeling of proteins involved in the physiological Ca2+ release from sarcoplasmic reticulum of skeletal muscle.
Topics: Animals; Calcium; Dantrolene; Drug Design; In Vitro Techniques; Mice; Molecular Structure; Muscle Co | 2005 |