Page last updated: 2024-12-04

platinum tetrachloride

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

platinum tetrachloride: see also platinum chloride [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

platinum chloride: RN given refers to cpd with unspecified MF; structure in first source: K2PtCl; see also platinum tetrachloride [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

platinum dichloride : A platinum coordination entity consisting of platinum(II) bound to two chlorine atoms. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID26031
MeSH IDM0101935
PubMed CID2770
CHEBI ID49801
MeSH IDM0101935

Synonyms (88)

Synonym
platinate(2-), dipotassium
AC-18114
cl4pt
13454-96-1
platinate(2-), diammonium
platinate(2-), diammonium, (sp-4-1)-
nsc-271964
nsc271964
nsc271963
platinate(2-), disodium, (sp-4-1)-
einecs 236-645-1
platinum (iv) chloride
tetrachloroplatinum
hsdb 6346
platinum tetrachloride
platinum(iv) chloride
platinum(iv) chloride, >=99.9% trace metals basis
wln: ka2 pt-g4
platinate(2-), dipotassium, (sp-4-1)-
nsc175496
potassium platinum(ii) tetrachloride k2[ptcl4]
platinum(iv) chloride, 96%
platinum(iv) chloride, >=99.99% trace metals basis
unii-w3yug71tu2
AKOS015904096
FBEIPJNQGITEBL-UHFFFAOYSA-J
platinum(iv) chloride, premion?
platinum(iv) chloride (99.9%-pt)
mfcd00011182
ptcl4
platinum(iv)chloride
FT-0700580
Q426312
platinum( cento) tetrachloride
CS-0082414
platinum(iv) chloride, 99%
sodium tetrachloroplatinate(ii) solution
AC-18115
DIVK1C_000890
KBIO1_000890
SPECTRUM_001531
NCGC00178241-01
SPECTRUM5_001168
IDI1_000890
einecs 233-034-1
platinous chloride
platinum dichloride
hsdb 6340
platinum(ii) chloride
muriate of platinum
platinum chloride
platinum(ii) di-chloride
platinum(ii) chloride, >=99.9% trace metals basis
platinum(ii) chloride, 99.99% trace metals basis
platinum(ii) chloride, 98%
KBIOSS_002367
KBIO2_004579
KBIO3_002647
KBIO2_002011
KBIO2_007147
KBIOSS_002011
KBIOGR_001443
NINDS_000890
SPECTRUM4_000842
SPBIO_000718
SPECTRUM2_000899
SPECTRUM3_001504
BSPBIO_003147
dichloroplatinum
platinium dichloride
CHEBI:49801 ,
10025-65-7
platinum(2+) dichloride
unii-896sq4tdhw
AKOS015903723
cl2pt
CLSUSRZJUQMOHH-UHFFFAOYSA-L
DTXSID6064901
AB01562953_01
mfcd00011181
platinum(ii) chloride, premion?
platinchlorid
platinum(ii) chlor
Q420989
CS-0040180
C71024
platinum( cento)chloride
SY011160

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" The present study investigated the bioavailability of platinum chloride for the zebrafish (Danio rerio) and the ramshorn snail (Marisa cornuarietis) and determined the bioaccumulation rate of platinum."( Uptake of platinum by zebrafish (Danio rerio) and ramshorn snail (Marisa cornuarietis) and resulting effects on early embryogenesis.
Haus, N; Köhler, HR; Osterauer, R; Sures, B, 2009
)
0.35
" Despite the bioavailability of these metals to plants and animals, studies determining the effects of PGMs on organisms are extremely rare."( Histopathological alterations and induction of hsp70 in ramshorn snail (Marisa cornuarietis) and zebrafish (Danio rerio) embryos after exposure to PtCl(2).
Köhler, HR; Osterauer, R; Triebskorn, R, 2010
)
0.36

Dosage Studied

ExcerptRelevanceReference
"In experiments with rats dose-response relationships of alimentary PtCl2 and PtCl4 were investigated."( Dose-response relationships of alimentary PtCl2 and PtCl4 in growing rats.
Bader, R; Kirchgessner, M; Reichlmayr-Lais, AM, 1992
)
0.28
"In experiments with rats dose-response relationships of alimentary PtCl2 and PtCl4 were investigated."( Dose-response relationships of alimentary PtCl2 and PtCl4 in growing rats.
Bader, R; Kirchgessner, M; Reichlmayr-Lais, AM, 1992
)
0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
reagentA substance used in a chemical reaction to detect, measure, examine, or produce other substances.
catalystA substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
platinum coordination entity
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (1)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
hypothetical protein, conservedTrypanosoma bruceiPotency10.00000.223911.245135.4813AID624173
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (88)

TimeframeStudies, This Drug (%)All Drugs %
pre-199012 (13.64)18.7374
1990's7 (7.95)18.2507
2000's36 (40.91)29.6817
2010's30 (34.09)24.3611
2020's3 (3.41)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 25.29

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index25.29 (24.57)
Research Supply Index4.30 (2.92)
Research Growth Index4.92 (4.65)
Search Engine Demand Index29.35 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (25.29)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Case Studies2 (2.74%)4.05%
Observational0 (0.00%)0.25%
Observational0 (0.00%)0.25%
Other18 (100.00%)84.16%
Other71 (97.26%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]