[no definition available]
Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle;
Voltage-gated calcium channel subunit alpha Cav1.2
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| phenytoin | Cavia porcellus (domestic guinea pig) | IC50 | 125.0000 | 1 | 1 |
| amiodarone | Cavia porcellus (domestic guinea pig) | IC50 | 0.2700 | 1 | 3 |
| amlodipine | Cavia porcellus (domestic guinea pig) | IC50 | 1.2000 | 1 | 3 |
| bepridil | Cavia porcellus (domestic guinea pig) | IC50 | 1.4000 | 1 | 1 |
| verapamil | Cavia porcellus (domestic guinea pig) | IC50 | 41.5000 | 1 | 1 |
| clotrimazole | Cavia porcellus (domestic guinea pig) | IC50 | 0.5900 | 1 | 2 |
| haloperidol | Cavia porcellus (domestic guinea pig) | IC50 | 1.7000 | 1 | 1 |
| imipramine | Cavia porcellus (domestic guinea pig) | IC50 | 8.3000 | 1 | 2 |
| nicardipine | Cavia porcellus (domestic guinea pig) | IC50 | 24.1000 | 1 | 3 |
| nifedipine | Cavia porcellus (domestic guinea pig) | IC50 | 0.0429 | 3 | 9 |
| nimodipine | Cavia porcellus (domestic guinea pig) | IC50 | 0.1100 | 1 | 1 |
| nitrendipine | Cavia porcellus (domestic guinea pig) | IC50 | 36.0000 | 1 | 1 |
| propranolol | Cavia porcellus (domestic guinea pig) | IC50 | 21.0000 | 1 | 4 |
| thioridazine | Cavia porcellus (domestic guinea pig) | IC50 | 1.3200 | 1 | 3 |
| diltiazem | Cavia porcellus (domestic guinea pig) | IC50 | 0.4500 | 1 | 3 |
| pinaverium | Cavia porcellus (domestic guinea pig) | IC50 | 1.7500 | 1 | 2 |
| sertindole | Cavia porcellus (domestic guinea pig) | IC50 | 8.9000 | 1 | 1 |
| mibefradil | Cavia porcellus (domestic guinea pig) | IC50 | 0.1560 | 1 | 1 |
| uk 68798 | Cavia porcellus (domestic guinea pig) | IC50 | 1,023.0000 | 1 | 1 |
| paliperidone | Cavia porcellus (domestic guinea pig) | IC50 | 398.1070 | 1 | 1 |
| moxifloxacin | Cavia porcellus (domestic guinea pig) | IC50 | 168.9000 | 1 | 3 |
| solifenacin | Cavia porcellus (domestic guinea pig) | IC50 | 6.3096 | 1 | 1 |
| quinidine | Cavia porcellus (domestic guinea pig) | IC50 | 16.6000 | 1 | 1 |
| mepirodipine | Cavia porcellus (domestic guinea pig) | IC50 | 1.8333 | 2 | 3 |
| cilnidipine | Cavia porcellus (domestic guinea pig) | IC50 | 5.3000 | 1 | 1 |