tris(2-aminoethyl)amine profile

Tris(2-aminoethyl)amine, also known as TREN, is a tripodal tetramine ligand. It is commonly used in coordination chemistry due to its ability to form stable complexes with various metal ions. TREN has been extensively studied for its potential applications in various fields, including catalysis, medicine, and materials science. The synthesis of TREN typically involves the reaction of diethylenetriamine with formaldehyde and ammonia. In terms of effects, TREN complexes have shown promising activity in areas such as anticancer therapy, antimicrobial activity, and enzyme inhibition. The importance of TREN lies in its versatility as a ligand, enabling the formation of complexes with diverse properties. Its ability to bind metal ions with high affinity and selectivity has led to its use in a wide range of applications, including drug delivery, bioimaging, and sensing. The study of TREN is driven by its potential to address critical challenges in various fields, such as developing novel therapies, improving diagnostic techniques, and creating advanced materials.'

tris(2-aminoethyl)amine: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	77731
CHEMBL ID	19823
CHEBI ID	30631
SCHEMBL ID	33394
MeSH ID	M0261257

Synonym
3gy3qsg6h5 ,
1,2-ethanediamine, n1,n1-bis(2-aminoethyl)-
diethylenetriamine, 4-(2-aminoethyl)-
unii-3gy3qsg6h5
4-(2-aminoethyl)diethylene triamine
nitrilotris(ethylamine)
4-(2-aminoethyl)diethylenetriamine
n,n-bis(2-aminoethyl)ethylenediamine
beta,beta',beta''-triaminotriethylamine
tren hp
2,2',2''-triaminotris(ethylamine)
einecs 223-857-4
1,2-ethanediamine, n,n-bis(2-aminoethyl)-
tris(aminoethyl)amine
2,2',2''-nitrilotris(ethylamine)
tri(2-aminoethyl)amine
tren
tris(2-aminoethyl)amine
2,2',2''-triaminotriethylamine
CHEBI:30631 ,
n,n-bis(2-aminoethyl)ethane-1,2-diamine
n,n-bis(2-aminoethyl)-1,2-ethanediamine
4097-89-6
14350-52-8
1, 2-ethanediamine, n,n-bis(2-aminoethyl)-, trihydrochloride
diethylenetriamine, 4-(2-aminoethyl)-, trihydrochloride
n',n'-bis(2-aminoethyl)ethane-1,2-diamine
n~1~,n~1~-bis(2-aminoethyl)-1,2-ethanediamine
nsc100649
tris(2-aminoethyl)amine, 96%
NCIOPEN2_006762
CHEMBL19823
mbylvokeddqjdy-uhfffaoysa-
inchi=1/c6h18n4/c7-1-4-10(5-2-8)6-3-9/h1-9h2
2,2',2''-nitrilotriethylamine
taea
T1243
n',n'-bis(2-azanylethyl)ethane-1,2-diamine
A825374
AKOS006221191
nsc 100649
n(1),n(1)-bis(2-aminoethyl)-1,2-ethanediamine
BP-20437
FT-0635124
tris(2-aminoethyl)-amine
tris (2-aminoethyl)amine
tris-(2-aminoethyl)-amine
tris-(2-aminoethyl)amine
tris-(aminoethyl)amine
SCHEMBL33394
2,2',2'-nitrilotriethylamine
DTXSID4063296
tris (2-aminoethyl) amine
tris[2-aminoethyl]amine
tris(2-aminoethyl)amine, technical, >=90% (gc)
2,2',2'-triaminotriethylamine
mfcd00008177
n1,n1-bis(2-aminoethyl)ethane-1,2-diamine
E70306
Q7843931
STR10055
CS-W016352
n,n-bis-(2-amino-ethyl)-ethane-1,2-diamine
n,n,n-tris(2-aminoethyl)amine
n1,n1-bis(2-aminoethyl)-1,2-ethanediamine
nitrilotriethylamine
EN300-203190

Class	Description
tetramine	Any polyamine that contains four amino groups.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Assay ID	Title	Year	Journal	Article
AID197832	Binding constant for spermine binding to Ribonuclease S (RNA ase) by saturation curve method	1999	Bioorganic & medicinal chemistry letters, May-03, Volume: 9, Issue:9	Design and semisynthesis of spermine-sensitive Ribonuclease S'.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	5 (8.20)	18.2507
2000's	20 (32.79)	29.6817
2010's	32 (52.46)	24.3611
2020's	4 (6.56)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (1.64%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	60 (98.36%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
ammonium hydroxide azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2.	2.04	1	azane; gas molecular entity; mononuclear parent hydride	EC 3.5.1.4 (amidase) inhibitor; metabolite; mouse metabolite; neurotoxin; NMR chemical shift reference compound; nucleophilic reagent; refrigerant
bromide Bromides: Salts of hydrobromic acid, HBr, with the bromine atom in the 1- oxidation state. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)	2.08	1	halide anion; monoatomic bromine
chlorine chloride : A halide anion formed when chlorine picks up an electron to form an an anion.	3.3	6	halide anion; monoatomic chlorine	cofactor; Escherichia coli metabolite; human metabolite
glycine [no description available]	2.03	1	alpha-amino acid; amino acid zwitterion; proteinogenic amino acid; serine family amino acid	EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor; fundamental metabolite; hepatoprotective agent; micronutrient; neurotransmitter; NMDA receptor agonist; nutraceutical
glycerol Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.	7.11	1	alditol; triol	algal metabolite; detergent; Escherichia coli metabolite; geroprotector; human metabolite; mouse metabolite; osmolyte; Saccharomyces cerevisiae metabolite; solvent
hydrogen carbonate Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.. hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.	2.05	1	carbon oxoanion	cofactor; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
hydrogen Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.. dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.	2.49	2	elemental hydrogen; elemental molecule; gas molecular entity	antioxidant; electron donor; food packaging gas; fuel; human metabolite
nickel Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.. nickel ion : A nickel atom having a net electric charge.. nickel atom : Chemical element (nickel group element atom) with atomic number 28.	2.73	3	metal allergen; nickel group element atom	epitope; micronutrient
nitrates Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.	2.04	1	monovalent inorganic anion; nitrogen oxoanion; reactive nitrogen species
spermidine [no description available]	2	1	polyazaalkane; triamine	autophagy inducer; fundamental metabolite; geroprotector
spermine [no description available]	2.4	2	polyazaalkane; tetramine	antioxidant; fundamental metabolite; immunosuppressive agent
urea pseudourea: clinical use; structure. isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.	9.06	4	isourea; monocarboxylic acid amide; one-carbon compound	Daphnia magna metabolite; Escherichia coli metabolite; fertilizer; flour treatment agent; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
oxyquinoline Oxyquinoline: An antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics.. quinolin-8-ol : A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes.	2.13	1	monohydroxyquinoline	antibacterial agent; antifungal agrochemical; antiseptic drug; iron chelator
acetohydroxamic acid acetohydroxamic acid: urease inhibitor. oxime : Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes.. N-hydroxyacetimidic acid : A carbohydroximic acid consisting of acetimidic acid having a hydroxy group attached to the imide nitrogen.. acetohydroxamic acid : A member of the class of acetohydroxamic acids that is acetamide in which one of the amino hydrogens has been replaced by a hydroxy group.	2.13	1	acetohydroxamic acids; carbohydroximic acid	algal metabolite; EC 3.5.1.5 (urease) inhibitor
fluorouracil Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.. 5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.	2.25	1	nucleobase analogue; organofluorine compound	antimetabolite; antineoplastic agent; environmental contaminant; immunosuppressive agent; radiosensitizing agent; xenobiotic
guanidine Guanidine: A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.. guanidine : An aminocarboxamidine, the parent compound of the guanidines.	2.41	2	carboxamidine; guanidines; one-carbon compound
n-methyl-d-glucamine dithiocarbamate N-methyl-D-glucamine dithiocarbamate: antidote for cadmium intoxication; repeated administration can result in reduction in cadmium levels of kidney & liver; structure given in first source	1.99	1
trientine Trientine: An ethylenediamine derivative used as stabilizer for EPOXY RESINS, as ampholyte for ISOELECTRIC FOCUSING and as chelating agent for copper in HEPATOLENTICULAR DEGENERATION.. TETA : An azamacrocyle in which four nitrogen atoms at positions 1, 4, 8 and 11 of a fouteen-membered ring are each substituted with a carboxymethyl group.. 2,2,2-tetramine : A polyazaalkane that is decane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogens.	2.4	2	polyazaalkane; tetramine	copper chelator
sorbitol D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).	1.99	1	glucitol	cathartic; Escherichia coli metabolite; food humectant; human metabolite; laxative; metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite; sweetening agent
lysine Lysine: An essential amino acid. It is often added to animal feed.. lysine : A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6.. L-lysine : An L-alpha-amino acid; the L-isomer of lysine.	2.11	1	aspartate family amino acid; L-alpha-amino acid zwitterion; L-alpha-amino acid; lysine; organic molecular entity; proteinogenic amino acid	algal metabolite; anticonvulsant; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite
tyrosine Tyrosine: A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.. tyrosine : An alpha-amino acid that is phenylalanine bearing a hydroxy substituent at position 4 on the phenyl ring.	2.04	1	amino acid zwitterion; erythrose 4-phosphate/phosphoenolpyruvate family amino acid; L-alpha-amino acid; proteinogenic amino acid; tyrosine	EC 1.3.1.43 (arogenate dehydrogenase) inhibitor; fundamental metabolite; micronutrient; nutraceutical
adenosine monophosphate Adenosine Monophosphate: Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.	2.01	1	adenosine 5'-phosphate; purine ribonucleoside 5'-monophosphate	adenosine A1 receptor agonist; cofactor; EC 3.1.3.1 (alkaline phosphatase) inhibitor; EC 3.1.3.11 (fructose-bisphosphatase) inhibitor; fundamental metabolite; micronutrient; nutraceutical
trifluoroacetic acid Trifluoroacetic Acid: A very strong halogenated derivative of acetic acid. It is used in acid catalyzed reactions, especially those where an ester is cleaved in peptide synthesis.. trifluoroacetic acid : A monocarboxylic acid that is the trifluoro derivative of acetic acid.	1.99	1	fluoroalkanoic acid	human xenobiotic metabolite; NMR chemical shift reference compound; reagent
3-mercaptopropionic acid 3-Mercaptopropionic Acid: An inhibitor of glutamate decarboxylase. It decreases the GAMMA-AMINOBUTYRIC ACID concentration in the brain, thereby causing convulsions.. 3-mercaptopropanoic acid : A mercaptopropanoic acid that is propanoic acid carrying a sulfanyl group at position 3.	2.05	1	mercaptopropanoic acid	algal metabolite
benzoyl chloride benzoyl chloride: potential carcinogens in manufacturing process. benzoyl chloride : An acyl chloride consisting of benzene in which a hydrogen is replaced by an acyl chloride group. It is an important chemical intermediate for the manufacture of other chemicals, dyes, perfumes, herbicides and pharmaceuticals.	2.11	1	acyl chloride; benzenes	carcinogenic agent
epichlorohydrin Epichlorohydrin: A chlorinated epoxy compound used as an industrial solvent. It is a strong skin irritant and carcinogen.. epichlorohydrin : An epoxide that is 1,2-epoxypropene in which one of the methyl hydrogens is substituted by chlorine.	2.08	1	epoxide; organochlorine compound
tetraethylenepentamine [no description available]	2.42	2	polyazaalkane	copper chelator
nitrilotriacetic acid Nitrilotriacetic Acid: A derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.)	2.13	1	NTA; tricarboxylic acid	carcinogenic agent; nephrotoxic agent
iminodiacetic acid iminodiacetic acid: used as hepatobiliary imaging agent when labeled with Tc; RN given refers to parent cpd; structure. iminodiacetic acid : An amino dicarboxylic acid that is glycine in which one of the hydrogens attached to the nitrogen is substituted by a carboxymethyl group.	2.46	2	amino dicarboxylic acid; glycine derivative; non-proteinogenic alpha-amino acid	chelator
pyrimidine pyrimidine : The parent compound of the pyrimidines; a diazine having the two nitrogens at the 1- and 3-positions.	2.05	1	diazine; pyrimidines	Daphnia magna metabolite
indole-3-carbaldehyde indole-3-carbaldehyde: metabolite of tryptophan; structure. indole-3-carbaldehyde : A heteroarenecarbaldehyde that is indole in which the hydrogen at position 3 has been replaced by a formyl group.	2.03	1	heteroarenecarbaldehyde; indole alkaloid; indoles	bacterial metabolite; human xenobiotic metabolite; marine metabolite; plant metabolite
malondialdehyde Malondialdehyde: The dialdehyde of malonic acid.. malonaldehyde : A dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists in vivo mainly in the enol form.	2.05	1	dialdehyde	biomarker
rhodamine 6g rhodamine 6G: RN given refers to HCl	2.15	1
pyridine-2-carboxaldehyde pyridine-2-carboxaldehyde: structure in first source. 2-formylpyridine : A pyridinecarbaldehyde that is pyridine in which the hydrogen at position 2 is replaced by a formyl group.	2.1	1	pyridinecarbaldehyde
pentaethylenehexamine [no description available]	1.99	1
manganese Manganese: A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035). manganese(4+) : A manganese cation that is monoatomic and has a formal charge of +4.	2.48	2	elemental manganese; manganese group element atom	Escherichia coli metabolite; micronutrient
mercury Mercury: A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.. mercury(0) : Elemental mercury of oxidation state zero.	7.04	1	elemental mercury; zinc group element atom	neurotoxin
ruthenium Ruthenium: A hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM.	7.04	1	iron group element atom; platinum group metal atom
terbium Terbium: An element of the rare earth family of metals. It has the atomic symbol Tb, atomic number 65, and atomic weight 158.92.	2.03	1	f-block element atom; lanthanoid atom
cadmium Cadmium: An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.. elemental cadmium : An element in the zinc group of the periodic table with atomic number 48, atomic mass 112, M.P. 321degreeC, and B.P. 765degreeC). An odourless, tasteless, and highly poisonous soft, ductile, lustrous metal with electropositive properties. It has eight stable isotopes: (106)Cd, (108)Cd,(110)Cd, (111)Cd, (112)Cd, (113)Cd, (114)Cd and (116)Cd, with (112)Cd and (114)Cd being the most common.	2.68	3	cadmium molecular entity; zinc group element atom
chromium Chromium: A trace element that plays a role in glucose metabolism. It has the atomic symbol Cr, atomic number 24, and atomic weight 52. According to the Fourth Annual Report on Carcinogens (NTP85-002,1985), chromium and some of its compounds have been listed as known carcinogens.. chromium ion : An chromium atom having a net electric charge.. chromium atom : A chromium group element atom that has atomic number 24.	1.99	1	chromium group element atom; metal allergen	micronutrient
gadolinium Gadolinium: An element of the rare earth family of metals. It has the atomic symbol Gd, atomic number 64, and atomic weight 157.25. Its oxide is used in the control rods of some nuclear reactors.	2.42	2	f-block element atom; lanthanoid atom
gold Gold: A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.	7.51	2	copper group element atom; elemental gold
chromates Chromates: Salts of chromic acid containing the CrO(2-)4 radical.. chromate(2-) : A chromium oxoanion resulting from the removal of two protons from chromic acid.	2.05	1	chromium oxoanion; divalent inorganic anion	oxidising agent
lead nitrate lead nitrate: RN given refers to unspecified lead nitrate	2.04	1	inorganic nitrate salt; lead coordination entity
cadmium nitrate cadmium nitrate: RN given refers to parent cpd. cadmium nitrate : An inorganic nitrate salt having Cd(2+) as the counterion.	2.04	1	cadmium salt; inorganic nitrate salt	carcinogenic agent; genotoxin; hepatotoxic agent
hexafluorosilicate hexafluorosilicate: structure	2.06	1	silicon coordination entity
fluorides [no description available]	2.06	1	halide anion; monoatomic fluorine
transferrin Transferrin: An iron-binding beta1-globulin that is synthesized in the LIVER and secreted into the blood. It plays a central role in the transport of IRON throughout the circulation. A variety of transferrin isoforms exist in humans, including some that are considered markers for specific disease states.	2.06	1
3-chloropropyltrimethoxysilane [no description available]	2.05	1
cyclen cyclen: macrocyclic polyamine metal-complexing agent. 1,4,7,10-tetraazacyclododecane : An azacycloalkane that is cyclododecane in which the carbon atoms at positions 1, 4, 7 and 10 are replaced by nitrogen atoms.	2.44	2	azacycloalkane; crown amine; saturated organic heteromonocyclic parent
cyclam cyclam: RN given refers to parent cpd; structure given in first source	2.01	1	azacycloalkane; crown amine; saturated organic heteromonocyclic parent
trioctyl phosphine oxide [no description available]	2.05	1
triazoles Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.	2.05	1	1,2,3-triazole
cryptand 2.2 cryptand 2.2: a macrocyclic diaza-crown ether; structure given in first source	2.05	1
cobalt Cobalt: A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.. cobalt(1+) : A monovalent inorganic cation obtained from cobalt.. cobalt atom : A cobalt group element atom that has atomic number 27.	3.01	4	cobalt group element atom; metal allergen	micronutrient
beta-lipotropin, gln(9)- corynebactin: a triscatechol derivative of a cyclic triserine lactone; siderophore synthesized by Corynebacterium diphtheriae. corynebactin : A crown compound that is enterobactin in which the pro-R hydrogens at positions 2, 6 and 10 of the trilactone backbone are replaced by methyl groups, and in which a glycine spacer separates the trilactone backbone from each of the catecholamide arms. It is the endogenous siderophore of Bacillus subtilis, used for the acquisition of iron.	2.03	1	catechols; crown compound; macrocyclic lactone	bacterial metabolite; metabolite
4-(3-trifluoromethyldiazirino)benzoic acid [no description available]	2	1
tris(2-pyridylmethyl)amine tris(2-pyridylmethyl)amine: structure in first source	2.13	1
trithiocyanuric acid trithiocyanuric acid: rubber curative; RN given refers to parent cpd	2.1	1
thiourea Thiourea: A photographic fixative used also in the manufacture of resins. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance may reasonably be anticipated to be a carcinogen (Merck Index, 9th ed). Many of its derivatives are ANTITHYROID AGENTS and/or FREE RADICAL SCAVENGERS.. thiourea : The simplest member of the thiourea class, consisting of urea with the oxygen atom substituted by sulfur.	7.81	3	one-carbon compound; thioureas; ureas	antioxidant; chromophore
D-fructopyranose [no description available]	2	1	cyclic hemiketal; D-fructose; fructopyranose	sweetening agent
3,4-diaminocyclobut-3-ene-1,2-dione 3,4-diaminocyclobut-3-ene-1,2-dione: structure in first source	2.17	1
quinine [no description available]	2.17	1	cinchona alkaloid	antimalarial; muscle relaxant; non-narcotic analgesic
lead Lead: A soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.2, symbol Pb.	2.73	3	carbon group element atom; elemental lead; metal atom	neurotoxin
cysteine Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3.	2.25	1	cysteinium	fundamental metabolite
trimethoxysilane [no description available]	2.05	1
oxalates Oxalates: Derivatives of OXALIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that are derived from the ethanedioic acid structure.	2.08	1
1-palmitoyl-2-oleoylphosphatidylcholine 1-palmitoyl-2-oleoylphosphatidylcholine: RN given refers to (Z)-isomer	2.1	1
bis(2-pyridyl)methylamine bis(2-pyridyl)methylamine: structure in first source	2.13	1
phosphatidylcholines Phosphatidylcholines: Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.	2.1	1	1,2-diacyl-sn-glycero-3-phosphocholine
chitosan [no description available]	7.04	1
guanosine monophosphate Guanosine Monophosphate: A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.. guanosine 5'-monophosphate : A purine ribonucleoside 5'-monophosphate having guanine as the nucleobase.	2.01	1	guanosine 5'-phosphate; purine ribonucleoside 5'-monophosphate	biomarker; Escherichia coli metabolite; metabolite; mouse metabolite

Condition	Relationship Strength	Studies
Cancer of Liver [description not available]	2.43	2
Liver Neoplasms Tumors or cancer of the LIVER.	2.43	2
Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)	2.4	2
Experimental Hepatoma [description not available]	2	1

tris(2-aminoethyl)amine

Description

Cross-References

Synonyms (67)

Drug Classes (1)

Bioassays (1)

Research

Studies (61)

Market Indicators

Research Demand Index: 45.24

Study Types