| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
carbamates
[no description available] | 2.05 | 1 | 0 | amino-acid anion | |
mannitol
[no description available] | 2 | 1 | 0 | mannitol | allergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent |
ketene
ketene: structure. ketene : Carbonyl compounds where the C=O bond is conjugated to an alkylidene group. | 2.05 | 1 | 0 | ketene | |
cyanates
Cyanates: Organic salts of cyanic acid containing the -OCN radical.. cyanates : Salts and esters of cyanic acid, HOC#N; compounds carrying the cyanate functional group -O-C#N.. isocyanates : Organonitrogen compounds that are derivatives of isocyanic acid; compounds containing the isocyanate functional group -N=C=O (as opposed to the cyanate group, -O-C#N). | 2.05 | 1 | 0 | | |
pederin
pederin: isolated from beetles, Paederus fuscipes; minor descriptor (75-84); on-line & Index Medicus search PYRANS (75-84); RN given refers to (2S-(2alpha(R*(R*(2S*,5S*,6S*))),4beta,6beta(R*)))-isomer. pederin : A polyketide and carboxamide produced by a (Pseudomonas) bacterial endosymbiont of certain rove beetles (genus Paederus). Pederin is the agent responsible for the vesicant effects (linear or Paederus dermatitis) when the beetle is crushed against the skin. It is a powerful inhibitor of protein biosynthesis and mitosis and a potent antitumour agent. | 3.55 | 2 | 0 | cyclic ketal;
diol;
oxanes;
polyketide;
secondary alcohol;
secondary carboxamide | antimitotic;
antineoplastic agent;
bacterial metabolite;
vesicant |
onnamide
onnamide: structure given in first source; isolated from marine sponges | 1.97 | 1 | 0 | | |
psymberin
psymberin: from the Indo-Pacific marine sponge Ircinia ramosa; structure in first source | 3.55 | 2 | 0 | hydroxybenzoic acid | |
mycalamide a
mycalamide A: structure given in first source; RN given refers to (2R-(2alpha,2(S*(S*)),5beta,6beta))-isomer; isolated from marine sponges | 4.36 | 6 | 0 | disaccharide | |
warfarin
Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group. | 3.55 | 2 | 0 | benzenes;
hydroxycoumarin;
methyl ketone | |