A sodium- and chloride-dependent betaine transporter that is encoded in the genome of mouse. [OMA:P31651, PRO:DNx]
Na(+)/Cl(-) betaine/GABA transporter;
Sodium- and chloride-dependent GABA transporter 2;
GAT-2;
Solute carrier family 6 member 12
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| beta-alanine | Mus musculus (house mouse) | IC50 | 331.1310 | 1 | 1 |
| guvacine | Mus musculus (house mouse) | IC50 | 744.8895 | 2 | 2 |
| nipecotic acid | Mus musculus (house mouse) | IC50 | 794.3280 | 2 | 2 |
| no 711 | Mus musculus (house mouse) | IC50 | 815.4785 | 2 | 2 |
| nortriptyline | Mus musculus (house mouse) | IC50 | 170.4120 | 1 | 2 |
| 3-aminobutyric acid | Mus musculus (house mouse) | IC50 | 812.8310 | 1 | 1 |
| tiagabine | Mus musculus (house mouse) | IC50 | 150.1350 | 4 | 4 |
| n-(4,4-diphenyl-3-butenyl)nipecotic acid | Mus musculus (house mouse) | IC50 | 371.5350 | 2 | 2 |
| n-(1-benzyl-4-piperidinyl)-2,4-dichlorobenzamide | Mus musculus (house mouse) | IC50 | 31.8114 | 1 | 2 |
| nipecotic acid | Mus musculus (house mouse) | IC50 | 49,647.8020 | 5 | 7 |
| nipecotic acid, (s)-isomer | Mus musculus (house mouse) | IC50 | 758.5780 | 2 | 2 |
| nnc 05-2090 | Mus musculus (house mouse) | IC50 | 1.4000 | 1 | 1 |
| nnc 05-2090 | Mus musculus (house mouse) | Ki | 1.4000 | 1 | 1 |
| snap 5114 | Mus musculus (house mouse) | IC50 | 350.9677 | 3 | 3 |