Page last updated: 2024-08-07 22:36:48
DNA ligase
A protein that is a translation product of the 30 gene in Tequatrovirus T4. [PRO:DNx, UniProtKB:P00970]
Synonyms
EC 6.5.1.1;
Polydeoxyribonucleotide synthase [ATP]
Research
Bioassay Publications (3)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| chloroquine | Tequatrovirus T4 | IC50 | 823.0000 | 2 | 4 |
| camptothecin | Tequatrovirus T4 | IC50 | 300.0000 | 1 | 1 |
NAD+-dependent DNA ligase (Rv3014c) from Mycobacterium tuberculosis: novel structure-function relationship and identification of a specific inhibitor.Proteins, , Oct-01, Volume: 69, Issue:1, 2007
NAD+-dependent DNA Ligase (Rv3014c) from Mycobacterium tuberculosis. Crystal structure of the adenylation domain and identification of novel inhibitors.The Journal of biological chemistry, , Aug-26, Volume: 280, Issue:34, 2005