Page last updated: 2024-08-07 10:15:21
G2/mitotic-specific cyclin-B
[no definition available]
Synonyms
Research
Bioassay Publications (19)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 17 (89.47) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (31)
Drugs with Inhibition Measurements
N2-substituted O6-cyclohexylmethylguanine derivatives: potent inhibitors of cyclin-dependent kinases 1 and 2.Journal of medicinal chemistry, , Jul-15, Volume: 47, Issue:15, 2004
Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives.Journal of medicinal chemistry, , Aug-01, Volume: 45, Issue:16, 2002
Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles.Journal of medicinal chemistry, , Jul-27, Volume: 43, Issue:15, 2000
N2-substituted O6-cyclohexylmethylguanine derivatives: potent inhibitors of cyclin-dependent kinases 1 and 2.Journal of medicinal chemistry, , Jul-15, Volume: 47, Issue:15, 2004
Structure-based design of 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinases 1 and 2.Bioorganic & medicinal chemistry letters, , Sep-15, Volume: 13, Issue:18, 2003
Pyrazolo[3,4-c]pyridazines as novel and selective inhibitors of cyclin-dependent kinases.Journal of medicinal chemistry, , Nov-03, Volume: 48, Issue:22, 2005
Docking-based development of purine-like inhibitors of cyclin-dependent kinase-2.Journal of medicinal chemistry, , Jun-29, Volume: 43, Issue:13, 2000
Cyclin-dependent kinase inhibition by new C-2 alkynylated purine derivatives and molecular structure of a CDK2-inhibitor complex.Journal of medicinal chemistry, , Apr-06, Volume: 43, Issue:7, 2000
Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors.Bioorganic & medicinal chemistry, , Volume: 7, Issue:7, 1999
Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases.Bioorganic & medicinal chemistry letters, , Apr-07, Volume: 8, Issue:7, 1998
Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives.The Journal of biological chemistry, , Sep-02, Volume: 280, Issue:35, 2005
Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors.Bioorganic & medicinal chemistry, , Volume: 7, Issue:7, 1999
Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases.Bioorganic & medicinal chemistry letters, , Apr-07, Volume: 8, Issue:7, 1998
Structure-based design of 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinases 1 and 2.Bioorganic & medicinal chemistry letters, , Sep-15, Volume: 13, Issue:18, 2003
Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles.Journal of medicinal chemistry, , Jul-27, Volume: 43, Issue:15, 2000
Pyrazolo[3,4-c]pyridazines as novel and selective inhibitors of cyclin-dependent kinases.Journal of medicinal chemistry, , Nov-03, Volume: 48, Issue:22, 2005
Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin.Journal of medicinal chemistry, , Feb-10, Volume: 48, Issue:3, 2005
Structure-based design and synthesis of 2-benzylidene-benzofuran-3-ones as flavopiridol mimics.Journal of medicinal chemistry, , Apr-25, Volume: 45, Issue:9, 2002