Ampicillin: Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
ampicillin : A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 6249 |
| CHEMBL ID | 174 |
| CHEBI ID | 28971 |
| CHEBI ID | 53713 |
| SCHEMBL ID | 3526 |
| MeSH ID | M0001025 |
| Synonym |
|---|
| BIDD:GT0184 |
| MLS001074168 |
| d-(-)-ampicillin |
| duphacillin |
| ultrabron |
| texcillin |
| ab-pc |
| totalciclina |
| pen ampil |
| orbicilina |
| supen |
| amfipen v |
| ampivax |
| morepen |
| servicillin |
| acillin |
| penicline |
| ampicillin a |
| guicitrina |
| ampivet |
| wy-5103 |
| ampimed |
| ampikel |
| aminobenzylpenicillin |
| nsc-528986 |
| sk-ampicillin |
| amplital |
| ampicil |
| britacil |
| ponecil |
| ampichel |
| ampicillin acid |
| ro-ampen |
| amplacilina |
| ampifarm |
| lifeampil |
| amfipen |
| brl 1341 |
| ay 6108 |
| norobrittin |
| princillin |
| totapen |
| bonapicillin |
| sq 17382 |
| ampi-co |
| pen a |
| ampicin |
| qidamp |
| ampicillin anhydrate |
| amplin |
| d-cillin |
| amplipenyl |
| sumipanto |
| vampen |
| penimic |
| penbrock |
| divercillin |
| cimex |
| hi 63 |
| rosampline |
| semicillin |
| trifacilina |
| binotal |
| penbritin paediatric |
| penbristol |
| ab-pc sol |
| ampi-tab |
| penicillin, (aminophenylmethyl)- |
| racenacillin |
| semicillin r |
| ampiscel |
| nuvapen |
| amplisom |
| amblosin |
| delcillin |
| ultrabion |
| pentrex |
| d-ampicillin |
| doktacillin |
| pensyn |
| viccillin |
| novo-ampicillin |
| KBIO1_000466 |
| DIVK1C_000466 |
| (2s,5r,6r)-6-{[(2r)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| ampicillin (usp/inn) |
| abpc |
| omnipen (tn) |
| anhydrous ampicillin (jp17) |
| D00204 |
| SPECTRUM_000050 |
| SPECTRUM5_000814 |
| BSPBIO_000128 |
| BPBIO1_000142 |
| IDI1_000466 |
| SMP1_000211 |
| PRESTWICK2_000114 |
| (2s,5r,6r)-6-{[(2r)-2-amino-2-phenylethanoyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| penicillin, aminobenzyl |
| ks-r1 |
| ukapen |
| pfizerpen-a |
| vidopen |
| ampicillin |
| C06574 |
| anhydrous ampicillin |
| 69-53-4 |
| tokiocillin |
| principen |
| omnipen |
| nsc528986 |
| brl-1341 |
| p-50 |
| totacillin (sodium) |
| ay-6108 |
| synpenin |
| (2s,5r,6r)-6-[[(2r)-2-amino-2-phenyl-acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| (2s,5r,6r)-6-[(r)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| amcill |
| ampicillin, anhydrous, 96.0-100.5% (anhydrous basis) |
| d-(-)-6-(alpha-aminophenylacetamido)penicillanic acid |
| NCGC00023282-05 |
| 1H8S |
| ampicillin, anhydrous |
| DB00415 |
| ampicillin (anhydrous) |
| ampicillin anhydrous |
| c16h19n3o4s |
| ampy-penyl |
| d-(-)-alpha-aminobenzylpenicillin |
| pentrexl |
| ampi-bol |
| campicillin |
| ampisyn |
| 6-(d-(2-amino-2-phenylacetamido))-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid |
| einecs 200-709-7 |
| amipenix s |
| roscillin |
| hsdb 3009 |
| adobacillin |
| ampicilline [inn-french] |
| 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-, d-(-)- |
| ampipenin |
| olin kid |
| pentrexyl |
| 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, (2s-(2alpha,5alpha,6beta(s*)))- |
| bayer 5427 |
| ba 7305 |
| d-(-)-alpha-aminopenicillin |
| pfizerpen a |
| ampicillinum [inn-latin] |
| ampicilina [inn-spanish] |
| 6-(d(-)-alpha-aminophenylacetamido)penicillanic acid |
| grampenil |
| ampicillina [dcit] |
| (2s,5r,6r)-6-((r)-2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid |
| tolomol |
| nsc 528986 |
| copharcilin |
| MLS000028405 , |
| smr000058352 |
| KBIO2_000430 |
| KBIO2_005566 |
| KBIOGR_000598 |
| KBIO3_001362 |
| KBIOSS_000430 |
| KBIO2_002998 |
| SPBIO_000818 |
| NINDS_000466 |
| SPECTRUM3_000301 |
| PRESTWICK1_000114 |
| SPBIO_002067 |
| SPECTRUM2_000769 |
| SPECTRUM4_000149 |
| PRESTWICK0_000114 |
| BSPBIO_001862 |
| PRESTWICK3_000114 |
| NCGC00023282-06 |
| 6beta-[(2r)-2-amino-2-phenylacetamido]-2,2-dimethylpenam-3alpha-carboxylic acid |
| ampicillinum |
| ampicilline |
| CHEBI:28971 , |
| aminobenzyl penicillin |
| ampicilina |
| HMS2090I11 |
| CHEMBL174 |
| wy 5103 |
| redicilin |
| alpha-aminobenzylpenicillin |
| ampicillanyl |
| CHEBI:53713 , |
| (2s,5r,6r)-6-[[(2r)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| NCGC00248937-01 |
| dtxsid4022602 , |
| cas-69-53-4 |
| dtxcid202602 |
| NCGC00255127-01 |
| tox21_301416 |
| tox21_113049 |
| ampicillin base |
| ampicillin [usan:ban:inn:jan] |
| ampicillina |
| bdbm50350465 |
| HMS2233H23 |
| unii-7c782967rd |
| 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((2r)-aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, (2s,5r,6r)- |
| 7c782967rd , |
| ampicillin [usan:usp:inn:ban:jan] |
| ay 6108 |
| ec 200-709-7 |
| EPITOPE ID:115008 |
| EPITOPE ID:116057 |
| AKOS015888156 |
| ampicillin [mi] |
| piperacillin sodium impurity a [ep impurity] |
| ampicillin [who-dd] |
| ampicillin [iarc] |
| ampicillin [mart.] |
| ampicillin [usan] |
| anhydrous ampicillin [jan] |
| 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, (2s-(2.alpha.,5.alpha.,6.beta.(s*)))- |
| ampicillin [usp monograph] |
| ampicillin [inn] |
| ampicillin [vandf] |
| ampicillinum [who-ip latin] |
| ampicillin [usp-rs] |
| sultamicillin impurity c [ep impurity] |
| ampicillin anhydrous [green book] |
| ampicillin anhydrous [who-ip] |
| ampicillin [who-ip] |
| ampicillin [hsdb] |
| ampicillin [ep monograph] |
| HY-B0522 |
| SCHEMBL3526 |
| NCGC00178944-03 |
| tox21_113049_1 |
| ampicillin anhydrous, pharmaceutical grade |
| OPERA_ID_1630 |
| (2s,5r,6r)-6-[(2r)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| ampicillin, anhydrous, european pharmacopoeia (ep) reference standard |
| d-(-)-a-aminobenzylpenicillin |
| AC-8805 |
| ampicillin, analytical standard |
| ampicillin, united states pharmacopeia (usp) reference standard |
| SBI-0051283.P003 |
| d-a-aminobenzylpenicillin |
| 6-(a-aminophenylacetamido)penicillanic acid |
| vidocillin |
| 6-d(-)-alpha-aminophenylacetamido-penicillanic acid |
| marcillin |
| pentritin |
| 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 9ci |
| anhydrous ampicillin, british pharmacopoeia (bp) reference standard |
| ampicillin acid; principen; amcill |
| (2s,5r,6r)-6-((r)-2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| (2s,5r,6r)-6-{[(2r)-2-amino-2-phenylethanoyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic |
| ampicillin,(s) |
| Q244150 |
| BRD-K68432770-001-08-0 |
| NCGC00023282-21 |
| gtpl10896 |
| A936108 |
| (2s,5r,6r)-6-(((r,e)-2-amino-1-hydroxy-2-phenylethylidene)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2r)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-, trihydrate,(2s,5r,6r)- |
| (2s,5r,6r)-6-[(r)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid |
| 6-[d(-)-a-aminophenylacetamido]penicillanic acid |
| ampicillin 1000 microg/ml in acetonitrile:methanol |
| d-(-)--aminobenzylpenicillin |
| BA166034 |
| EN300-127654 |
| sultamicillin impurity c (ep impurity) |
| ampicillin (ep monograph) |
| s01aa19 |
| (2s,5r,6r)-6-(((2r)-2-amino-2-phenylethanoyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid |
| j01ca01 |
| ampicillin (usp monograph) |
| (2s,5r,6r)-6-((2r)-2-amino-2-phenylacetylamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid |
| ampicillin (iarc) |
| vicillin s |
| ampicillin (mart.) |
| 6beta-((2r)-2-amino-2-phenylacetamido)-2,2-dimethylpenam-3alpha-carboxylic acid |
| (2s,5r,6r)-6-(((2r)-2-amino-2-phenylacetyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid |
| Z1603854590 |
Ampicillin (AMP) is a penicillin-class beta-lactam antibiotic widely used to treat infections caused by bacteria. Ampicillin-sulbactam is a first-line therapy for pneumonia and is mainly excreted by the kidney.
Apicillin has a single carboxyl group (-C(O)OH) within its structure which is suitable for forming ester compounds. Ampicillin-sulbactam has a wide range of antibacterial activity.
Ampicillin-sulbactam has a wide range of antibacterial activity that includes Gram-positive and Gram-negative aerobic and anaerobic bacteria. Ampicillin resistance has changed the epidemiology of neonatal sepsis.
Apicillin can cause peripheral nerve damage when injected perineurally. Ampicillin may act to lower plasma levels of oestrone sulphate by reducing the growth of bacteria in the gut.
Ampicillin treatment in the last trimester of pregnancy had no significant effect on the levels of estradiol, estriol, or cortisol in maternal plasma. Ampicillin was associated with a significant increase in urinary strains resistant to ampicillin and to mecillinam.
Ampicillin/Sulbactan is as safe and efficient as Amoxicillin/Clavulanate in the empiric treatment of upper respiratory infections in adults. Adverse drug reactions due to bacampicillin at all dose levels were less frequent than those of other anti-microbials.
The pharmacokinetic properties of lenampicillin (KBT-1585), a new ampicillin ester, were investigated in 41 healthy volunteers. The kinetics of sulbactam in postpartem women and in surgical patients were similar to the kinetics in young men. The half-life of sul bactam was altered in the elderly, during labor, in neonates and in patients with renal impairment.
| Excerpt | Reference | Relevance |
|---|---|---|
| " Data were interpreted in terms of a 3-compartment pharmacokinetic open model." | ( Antibacterial activity and pharmacokinetics of bacampicillin and ampicillin. Klastersky, J; Rozencweig, M; Staquet, M, 1976) | 0.51 |
| " In order to calculate the pharmacokinetic parameters, plasma levels were analyzed using an one-compartment open model, as well as area under the plasma concentration curve (AUC) and urinary excretion." | ( [Talampicillin hydrochloride: Comparison with amoxicillin and ampicillin in the antibacterial activity and pharmacokinetics (author's transl)]. Komiya, M; Naito, S; Ohtani, K; Shimizu, C; Tachibana, A; Yano, K, 1978) | 0.82 |
| " month pregnancy, women in labor and health controll persons) the serum levels of the mothers were analysed according to the pharmacokinetic parameter half-life of elimination." | ( [Clinical studies on the effect of pregnancy and labor on the pharmacokinetics of ampicillin]. Meinhold, P; Nöschel, H; Schröder, S; Voigt, R; Zenner, I, 1978) | 0.48 |
| " Peak serum values increased proportionally to the increase in dose; the serum half-life was similar in the three dose groups studied." | ( Pharmacokinetics of intravenous amoxicillin in pediatric patients. Goto, N; Pettit, D; Rudoy, RC; Uemura, H, 1979) | 0.26 |
| " The biological half-life of DKB was prolonged in pretreatment with ABPC and that of ABPC was shortened in pretreatment with DKB." | ( [Fundamental studies of combination of antibiotics, especially on pharmacokinetics. III. Combination of ampicillin and dibekacin (author's transl)]. Aratani, H; Nakatsuka, M, 1979) | 0.47 |
| " Area under the curve values and serum half-life values were similar in fasting and nonfasting patients." | ( Comparative pharmacokinetics of amoxicillin and ampicillin in infants and children. Clahsen, J; Ginsburg, CM; McCracken, GH; Thomas, ML, 1979) | 0.52 |
| " The pharmacokinetic analysis was made according to a two-compartment open model." | ( Pharmacokinetics of ampicillin and its prodrugs bacampicillin and pivampicillin in man. Boréus, LO; Ehrnebo, M; Nilsson, SO, 1979) | 0.58 |
| " Base and hydrochloride of pivampicillin are equivalent with respect to pharmacokinetic behaviour." | ( [Studies on the pharmacokinetic equivalence of pivampicillin base and hydrochloride in capsules and tablets (author's transl)]. Bozler, G; Fedorcak, V; Mielenz, H, 1977) | 0.8 |
| " The paper describes mathematical, laboratory and clinical aspects which must be examined in designing a protocol for pharmacokinetic experiments." | ( Pharmacokinetics--uses and abuses. Fell, PJ; Stevens, MT, 1975) | 0.25 |
| " The variations of these pharmacokinetic parameters were then examined using the three-way analysis of variance and linear regression equations." | ( Pharmacokinetics of amoxicillin: dose dependence after intravenous, oral, and intramuscular administration. O'Brien, WM; Rugloski, RJ; Spyker, DA; Vann, RL, 1977) | 0.26 |
| " Pharmacokinetic parameter values were consistent with urinary excretion characteristics." | ( Pharmacokinetics of ampicillin and methoxymethyl ester of hetacillin in dogs. Kjaer, TB; Madsen, PO; Welling, PG, 1977) | 0.58 |
| "The time course of ampicillin concentrations in the sera of three newborn infants during and upon termination of intravenous infusion at a constant rate can be described by a two-compartment pharmacokinetic model." | ( Pharmacokinetic model for serum concentrations of ampicillin in the newborn infant. Colburn, WA; Gilbaldi, M; Riley, HD; Takimoto, M; Yoshioka, H, 1976) | 0.84 |
| " The pharmacokinetic behavior of pirbenicillin and the other penicillins was analyzed by the two-compartment open model." | ( Pirbenicillin: pharmacokinetic parameters in mice. English, AR; Girard, D; Retsema, JA, 1976) | 0.26 |
| " Despite its in vitro and pharmacokinetic advantages, co-trimoxazole was not any more efficient than any other durg or no therapy in the treatment of salmonella gastroenteritis; it seems to have a role, however, in the treatment of typhoid fever and may be life-saving in patients infected with ampicillin- and chloramphenical-resistant strains." | ( Pharmacokinetics and efficacy of trimethoprim-sulfamethoxazole in the treatment of gastroenteritis in children. Marks, MI, 1975) | 0.43 |
| " injection were analysed according to a one and a two-compartment pharmacokinetic model." | ( Pharmacokinetic analysis of ampicillin concentration in neonates: comparison of two pharmacokinetic models and of two numerical methods. Driessen, O; Hermans, J; Sorgedrager, N; Spoor, M, 1975) | 0.55 |
| " Results indicate that changes in urine pH over a range encountered in clinically normal horses are unlikely to affect plasma pharmacokinetic variables of ampicillin sodium after IV administration of the drug." | ( Effect of changes in urine pH on plasma pharmacokinetic variables of ampicillin sodium in horses. Horspool, LJ; McKellar, QA; Sarasola, P, 1992) | 0.72 |
| " There was analytical relationship between the ampicillin half-life and efficiency of the renal function." | ( [Mathematical modeling of ampicillin pharmacokinetics in patients with altered excretory function of the kidneys]. Manuĭlov, KK, 1991) | 0.84 |
| "The pharmacokinetics of gentamicin in postpartum women with endomyometritis were characterized and models for predicting patient pharmacokinetic parameters were developed using multiple regression analysis." | ( Gentamicin pharmacokinetics in postpartum women with endomyometritis. Gibson, GA; Lawson, LA; Munar, MY; Samuels, P, 1991) | 0.28 |
| " Several serum pharmacokinetic parameters were similar for the two drugs after three intravenous doses were given to patients following surgery." | ( Pharmacokinetics of ampicillin and sulbactam in patients undergoing heart surgery. Müller, V; Sonntag, HG; Springsklee, M; Wildfeuer, A, 1991) | 0.6 |
| " A significant increase in elimination half-life (around 180 per cent), volume of distribution (130 per cent) and mean residence time (154 to 170 per cent) was observed in sheep infected by the parasite for four to 12 weeks." | ( Pharmacokinetics of ampicillin and pentobarbital in the course of subclinical fascioliasis in sheep. Alvinerie, M; Galtier, P; Houin, G; Larrieu, G; Tufenkji, AE, 1991) | 0.6 |
| " The pharmacodynamic activity of this drug was also determined by use of mean bactericidal titers against selected bacterial strains." | ( Ampicillin and sulbactam pharmacokinetics and pharmacodynamics in continuous ambulatory peritoneal dialysis (CAPD). Blackwell, BG; Craig, WA; Johnson, CA; Leggett, JE; Zimmerman, SW, 1990) | 1.72 |
| " The pharmacokinetic characteristics of sulbactam was similar to ampicillin after a single intravenous injection of 200 mg/kg in mice with a half-life of approximately 50 min." | ( Pharmacokinetics of sulbactam and ampicillin in mice and in dogs. Liu, CX; Lu, YL; Wang, JR, 1990) | 0.8 |
| "A pharmacokinetic study of ampicillin (6 mg/kg intravenous) revealed that the peak concentrations of 17." | ( Pharmacokinetics and distribution of ampicillin in plasma, milk and uterine fluid of female buffaloes. Banerjee, NC; Jayachandran, C; Singh, MK, 1990) | 0.85 |
| "We investigated the pharmacokinetic properties of sulbactam/ampicillin (S/A), after intravenous (0." | ( Pharmacokinetics of sulbactam/ampicillin in humans after intravenous and intramuscular injection. Ferrante, L; Prenna, M; Ripa, S, 1990) | 0.81 |
| "Clinical and pharmacokinetic studies on aztreonam (AZT) were performed in neonates." | ( [Clinical and pharmacokinetic studies on aztreonam in neonates]. Abe, T; Fujii, R; Hashira, S; Meguro, H; Tajima, T, 1990) | 0.28 |
| " The geriatric subjects had higher serum concentration and elimination half-life of the drug." | ( Ampicillin pharmacokinetics in Indian geriatric subjects. Adithan, C; Bapna, JS; Krishnan, M; Raveendran, R; Sriram, G, 1990) | 1.72 |
| " The pharmacokinetic parameters for both ampicillin and sulbactam were calculated by computer-based two-compartment nonlinear model." | ( Single-dose pharmacokinetics of intravenous ampicillin plus sulbactam in healthy elderly and young adult subjects. Bawdon, RE; Castle, S; Jones, A; Norman, DC; Rho, JP; Smith, K; Woo, M, 1989) | 0.8 |
| "Over the past 5 yr, we have conducted two clinical and two pharmacokinetic investigations of cefotaxime (CTX) and desacetylcefotaxime (dCTX) in neonates, infants, and children." | ( Cefotaxime and desacetylcefotaxime in neonates and children: a review of microbiologic, pharmacokinetic, and clinical experience. Jacobs, RF; Kearns, GL, ) | 0.13 |
| " The pharmacokinetic parameters of the two components are similar, both being eliminated primarily by renal excretion." | ( The pharmacokinetics of sultamicillin. Bruckner, G; Hampel, B; Koeppe, P; Lode, H, 1989) | 0.28 |
| " For pharmacokinetic investigation, SBT/ABPC at 30 or 60 mg/kg was administered by intravenous drip infusion over 30 minutes." | ( [Pharmacokinetic and clinical studies on sulbactam/ampicillin in the pediatric field]. Imamura, H; Nakayama, N; Tsuji, Y; Yanagi, T; Yanagishima, M; Yanai, M, 1989) | 0.53 |
| " The most rapid Tmax and the highest Cmax were achieved with lenampicillin." | ( Comparative pharmacokinetic study between lenampicillin, bacampicillin and amoxycillin. Jepson, AP; Sefton, AM; Sum, ZM; Williams, JD, 1989) | 0.78 |
| " In hemodialysis patients, the ampicillin half-life was 17." | ( Pharmacokinetics of ampicillin (2.0 grams) and sulbactam (1.0 gram) coadministered to subjects with normal and abnormal renal function and with end-stage renal disease on hemodialysis. Blum, RA; Harrison, NJ; Kohli, RK; Schentag, JJ, 1989) | 0.89 |
| " Although the kinetics of sulbactam in postpartem women and in surgical patients were similar to the kinetics in young men, the half-life of sulbactam (like that of ampicillin) was altered in the elderly, during labor, in neonates, and in patients with renal impairment." | ( Pharmacokinetics of sulbactam/ampicillin in humans: a review. Foulds, G, ) | 0.62 |
| " The basic pharmacokinetic characteristics of sulbactam after parenteral administration are similar to those of ampicillin." | ( Sulbactam/ampicillin. A review of its antibacterial activity, pharmacokinetic properties, and therapeutic use. Brogden, RN; Campoli-Richards, DM, 1987) | 0.89 |
| "An exact mathematical solution was derived to a pharmacodynamic model which illustrates bacterial survival in the presence of antibiotics." | ( A pharmacodynamic model for the activity of antibiotics against microorganisms under nonsaturable conditions. Nightingale, CH; Quintiliani, R; Zhi, J, 1986) | 0.27 |
| "Tissue penetration may be an important pharmacokinetic determinant to achieve the chemotherapeutic efficacy of antimicrobial agents." | ( A mouse model for simultaneous pharmacokinetic and efficacy studies of antibiotics at sites of infection. Renneberg, J; Walder, M, 1988) | 0.27 |
| " The two drugs showed a similar pharmacokinetic profile in humans." | ( Pharmacokinetics of sulbactam and ampicillin intravenously applied in combination to healthy volunteers and patients. Determination of the ratio of the two drugs in serum and in various tissues. Engel, K; Lenders, H; Potempa, J; Schilling, A; Schwiersch, U; von Castell, E; Wildfeuer, A, 1988) | 0.55 |
| "In this study, the pharmacokinetic parameters of 2 different beta-lactamase inhibitors (sulbactam and clavulanic acid) in combination with 2 different aminobenzylpenicillins (ampicillin and amoxycillin) were compared." | ( Comparative pharmacokinetics of sulbactam/ampicillin and clavulanic acid/amoxycillin in human volunteers. Bruckner, G; Hampel, B; Koeppe, P; Lode, H, 1988) | 0.73 |
| " A study has been performed to evaluate pharmacokinetic properties and clinical usefulness of SBTPC fine granules in the treatment of pediatric infections." | ( [Clinical and pharmacokinetic studies on sultamicillin fine granules in pediatrics]. Matsumoto, K; Nakanishi, Y; Nakazawa, S; Narita, A; Niino, K; Sato, H; Suzuki, H, 1988) | 0.27 |
| " Pharmacokinetic studies were done in 2 subjects (a male and a female) following single oral administrations of 5 mg/kg and 10 mg/kg SBTPC fine granules after meal." | ( [A study on pharmacokinetics, antimicrobial activity and clinical efficacy of sultamicillin in children]. Higashino, H; Hirabayashi, Y; Kitamura, N; Kobayashi, Y; Okazaki, H, 1988) | 0.27 |
| " Pharmacokinetic and clinical studies using SBTPC 10% fine granules were performed in pediatric patients with a variety of infections." | ( [Pharmacokinetic and clinical studies of sultamicillin fine granules in children]. Hayashi, K; Imamura, H; Nakayama, N; Tsuji, Y; Yanagi, T; Yanagishima, M; Yanai, M, 1988) | 0.27 |
| " The pharmacokinetic parameters of the antibiotics given separately were not altered by concurrent administration." | ( Effect of induced synovial inflammation on pharmacokinetics and synovial concentration of sodium ampicillin and kanamycin sulfate after systemic administration in ponies. Firth, EC; Klein, WR; Nouws, JF; Wensing, T, 1988) | 0.49 |
| " The pharmacokinetic analysis was carried out by applying a single-compartment kinetic model with zero-order absorption." | ( Pharmacokinetics of bacampicillin using a compartment model with zero-order absorption. Ecari, U; Ferrante, L; Mignini, F; Ripa, S; Ruffilli, MP, 1988) | 0.59 |
| "The pharmacokinetic properties of lenampicillin (KBT-1585), a new ampicillin ester, were investigated in 41 healthy volunteers." | ( Pharmacokinetic study of lenampicillin (KBT-1585) in healthy volunteers. Nakashima, M; Saito, A, 1986) | 0.84 |
| " Pharmacokinetic interaction between combination ampicillin sodium-gentamicin sulfate was not observed int he serum or synovia." | ( Prediction of pharmacokinetic profiles of ampicillin sodium, gentamicin sulfate, and combination ampicillin sodium-gentamicin sulfate in serum and synovia of healthy horses. Bowman, KF; Dix, LP; Riond, JL; Riviere, JE, 1986) | 0.79 |
| "Experimental studies with broiler birds revealed that medicated feed (flavophospholipol, vitamyacin A, and the A-149 antibiotic in stimulative doses), offered in the course of two weeks, led to changes in the pharmacokinetic parameters of ampicillin administered i/v (in the form of ampicillin-Na) and via the crop (in the form of ampicillin-trihydrate at 30 mg/kg)." | ( [Effect of feed antibiotics on ampicillin pharmacokinetics in chickens]. Mutafchieva, R; Pashov, D, 1986) | 0.74 |
| " Pharmacokinetic studies were carried out after slow (3 mn) intravenous administration of a single dose of 20 or 30 mg/kg in five categories of infants: premature, dysmature, full term newborn up to 8 days of age, infant aged 8 days to 1 month and infant beyond 1 month." | ( [Pharmacokinetics of apalcillin in pediatrics]. Akbaraly, JP; Heinzel, G; Martin, C; Peyraud, J; Sarlangue, J; Sautarel, M, 1985) | 0.27 |
| "The purpose of this study was to investigate the disposition of two aminopenicillins and their intra- and inter-individual variation in pharmacokinetic parameters in healthy, elderly volunteers." | ( Intra- and inter-individual variation in pharmacokinetics of intravenously infused amoxycillin and ampicillin to elderly volunteers. Alván, G; Huitfeldt, B; Sjövall, J, 1986) | 0.49 |
| " The pharmacokinetic parameters were estimated in a one-compartmental model by computer The ampicillin levels in the blood and urine of the patients did not practically differ at all the investigation periods (0." | ( [Ampicillin pharmacokinetics in pregnant women with acute pyelonephritis]. Akhtamova, ZM; Dorokhov, VV; Gurtovoĭ, BL; Kholodov, LE, 1985) | 1.4 |
| " At the terminal stage of chronic renal insufficiency the half-life of the drug and the area under the pharmacokinetic curve markedly increased and the plasma clearance decreased." | ( [Pharmacokinetics of ampicillin in patients with chronic renal insufficiency during hemodialysis and hemosorption]. Cherniakov, VL; Iakovlev, VP; Shcherbakov, VA; Shuster, AM; Skala, LZ, 1985) | 0.59 |
| "In this paper pharmacokinetic data of ampicillin in 9 pregnant women with H-gestosis are compared with those from 8 healthy pregnant women in the last trimenon." | ( [The pharmacokinetics of ampicillin in pregnant women with H-gestosis in the last trimester of pregnancy]. Müller, B; Peiker, G; Schröder, S, 1985) | 0.84 |
| " The single- and multiple-dose pharmacokinetic studies were performed on six healthy male volunteers." | ( Single- and multiple-dose pharmacokinetics of lenampicillin (KBT-1585) in healthy human subjects: comparative studies with amoxicillin. Acar, JF; Guibert, J; Kitzis, MD; Yamabe, S, 1985) | 0.52 |
| " The half-life of BL-P1654 (2." | ( Human pharmacokinetics of BL-P1654 compared with ampicillin. Clarke, JT; Kirby, WM; Libke, RD; Luthy, RP; Ralph, ED, 1974) | 0.51 |
| " In rabbit CSF, moxalactam had the greatest concentration and penetration, but rocephin had the longest half-life and duration of bactericidal activity." | ( Pharmacokinetics and bacteriologic efficacy of moxalactam, cefotaxime, cefoperazone, and rocephin in experimental bacterial meningitis. Loock, CA; McCracken, GH; Schaad, UB; Thomas, ML, 1981) | 0.26 |
| " By a combination of gentamicin plus ampicillin pharmacokinetic parameters are not influenced; while if gentamicin is combined with cefotaxim the apparent elimination halflife of gentamicin (beta-slope) is significantly reduced." | ( [Pharmacokinetics of combined antibiotic therapy in the newborn infant]. Bergt, U; Heimann, G; Schug, S, 1983) | 0.54 |
| "Sulbactam, a new beta-lactamase inhibitor, has pharmacokinetic characteristics in humans similar to those of ampicillin and amoxicillin." | ( Pharmacokinetics of sulbactam in humans. Foulds, G; Hayes, SL; Marshall, DC; McMahon, FG; O'Brien, MM; Stankewich, JP; Weidler, DJ, 1983) | 0.48 |
| " Chloramphenicol is mainly excreted after biotransformation and large differences in pharmacokinetic parameters are to be found, not only between birds and mammals, but also between avian species." | ( Pharmacokinetic aspects of penicillins, aminoglycosides and chloramphenicol in birds compared to mammals. A review. Dorrestein, GM; Rinzema, JD; van Gogh, H, 1984) | 0.27 |
| " The ultimate half-life t 1/2 of mezlocillin (46." | ( [Pharmacokinetics of mezlocillin. Comparison with ampicillin and influence of probenecid (author's transl)]. de Schepper, PJ; Tjandramaga, TB; Verbesselt, R; Verbist, L, 1982) | 0.52 |
| "A pharmacokinetic study of apalcillin was performed in 12 patients in an intensive-care unit." | ( Pharmacokinetics of apalcillin in intensive-care patients: study of penetration into the respiratory tract. Akbaraly, JP; Bergogne-Berezin, E; Chastre, J; Gibert, C; Heinzel, G; Pierre, J, 1984) | 0.27 |
| " Pharmacokinetic parameters were calculated according to a two-compartment open model." | ( Comparative pharmacokinetics of apalcillin and piperacillin. Borner, K; Elvers, A; Koeppe, P; Lode, H, 1984) | 0.27 |
| " The linearity study of the pharmacokinetic was carried out on 26 subjects who were given increasing doses (500, 1 000, 2 000, 3 000 mg) of apalcillin by the venous route." | ( [Pharmacokinetics of apalcillin. Study of linearity]. Akbaraly, JP; Auzerie, J; Bebear, C; Brachet-Liermain, A; Coux, C; Guyot, M; Heinzel, G; Quentin, C, 1984) | 0.27 |
| " The mean serum half-life of the drug (6." | ( Pharmacokinetic comparison of intravenous and oral chloramphenicol in patients with Haemophilus influenzae meningitis. Kolling, WM; Williams, T; Yogev, R, 1981) | 0.26 |
| " The pharmacokinetic parameters were computed according to the two-compartment open model." | ( Pharmacokinetics of potassium ampicillin. Kaumeier, S; Kisslinger, E; Neiss, A, 1980) | 0.55 |
| " Various simulations following rapid injection or continuous infusion are presented to demonstrate the general behavior of such a pharmacokinetic model." | ( Two-compartment pharmacokinetic models: computer simulations of their characteristics and clinical consequences. Abramson, FP, 1981) | 0.26 |
| " The rate of penetration of ampicillin into the blister fluid was lower than the rate of gastrointestinal absorption of bacampicillin, and the elimination of ampicillin from the blister fluid was slower than from serum; the half-life in blister fluid was approximately twice that in serum." | ( Pharmacokinetics of ampicillin in serum and in dermal suction blisters after oral administration of bacampicillin. Bergan, T; Digranes, A; Hellum, KB; Schreiner, A, ) | 0.75 |
| " Cmax in CSF was obtained at 15 minutes for carbenicillin and 30 minutes for ampicillin." | ( Comparative pharmacokinetics of ampicillin and carbenicillin in the cerebrospinal fluid of rabbits with staphylococcal meningitis with reference to half-lives and areas under the curve. Morikawa, Y, 1981) | 0.78 |
| " Up to five pharmacokinetic equations, which are voluntarily defined by the user, are simultaneously fitted to observed time courses." | ( A pharmacokinetic analysis program (multi) for microcomputer. Nakagawa, T; Tanigawara, Y; Uno, T; Yamaoka, K, 1981) | 0.26 |
| "A study protocol is described by means of which useful and pertinent information on possible alterations of pharmacokinetic parameters due to pregnancy can be investigated." | ( A protocol design for studying alterations of pharmacokinetic parameters due to pregnancy. Philipson, A, 1980) | 0.26 |
| "To compare the pharmacokinetic and pharmacodynamic activity of three drug regimens: cefotaxime plus metronidazole, cefoxitin, and ampicillin-sulbactam against two organisms frequently isolated in intraabdominal infection, Escherichia coli and Bacteroides fragilis." | ( Comparison of the pharmacodynamic activity of cefotaxime plus metronidazole with cefoxitin and ampicillin plus sulbactam. Nightingale, CH; Quintiliani, R; Sullivan, MC; Sweeney, KR, ) | 0.55 |
| "KINFIT is a nonlinear least-squares computer program designed to allow pharmacokinetic modeling of experimental data and to obtain pertinent parameter estimates based on the derived values." | ( KINFIT: a non linear least-squares computer program for the estimation of pharmacokinetic parameters after intravenous administration. Kaltenbach, ML; Vistelle, R, ) | 0.13 |
| " For the control of the model adequacy, the published pharmacokinetic data on the distribution of ceftazidime and ampicillin in serum and "skin blister" fluid were used." | ( [Analysis of ceftazidime and ampicillin tissue distribution using physiologic models of pharmacokinetics]. Manuĭlov, KK, 1993) | 0.79 |
| "To evaluate the pharmacodynamic antibacterial activity of ticarcillin-clavulanic acid (T-C) and ampicillin-sulbactam (A-S) combinations against reference bacterial strains in patients with end-stage renal disease maintained on long-term hemodialysis." | ( Comparison of ampicillin-sulbactam and ticarcillin-clavulanic acid in patients with chronic renal failure: effects of differential pharmacokinetics on serum bactericidal activity. Butler, SC; Hardin, TC; Jorgensen, JH; Ross, S; Wakeford, JH, ) | 0.71 |
| "This study evaluated the effects pregnancy had on pharmacokinetic parameters of ampicillin and sulbactam." | ( Pharmacokinetics of ampicillin and sulbactam in pregnancy. Bawdon, R; Chamberlain, A; Larsen, B; Thomas, S; White, S, 1993) | 0.84 |
| " Pharmacokinetic parameters were determined by fitting data (serum concentrations versus time) to a single-compartment model that provided elimination rate constants, beta-intercept (calculated concentration at 0 minutes), area under the time-versus-concentration curve, half-life of the drug, total body clearance, and volume of distribution." | ( Pharmacokinetics of ampicillin and sulbactam in pregnancy. Bawdon, R; Chamberlain, A; Larsen, B; Thomas, S; White, S, 1993) | 0.61 |
| " The plasma concentrations obtained over the infusion period correlated very well with predicted calculations based on pharmacokinetic parameters." | ( Pharmacokinetics and applications of ampicillin sodium as an intravenous infusion in the horse. McKellar, QA; Sarasola, P, 1993) | 0.56 |
| " The mean elimination half-life (t1/2 beta), the area-derived volume of distribution (Varea) and the total body clearance (ClB) values after the intravenous and intraosseous treatment were 86." | ( Pharmacokinetics of ampicillin administered intravenously and intraosseously to kittens. Bark, H; Glickman, A; Goldstein, R; Lavy, E; Shem-Tov, M; Ziv, G, 1995) | 0.61 |
| "The pharmacokinetic behaviour of an ampicillin/sulbactam (2:1) combination was studied after intramuscular administration of a single dose (20 mg/kg body weight: 13." | ( Comparative pharmacokinetics of an ampicillin/sulbactam combination administered intramuscularly in lactating sheep and goats. Cárceles, CM; Escudero, E; Espuny, A; Vicente, MS, 1996) | 0.85 |
| "The pharmacokinetic behaviour of a combination of ampicillin and sulbactam (2:1) in six sheep and six goats after single intravenous doses of 20 mg kg body weight-1 (13." | ( Single-dose pharmacokinetics of ampicillin/sulbactam (2:1) combination after intravenous administration to sheep and goats. Carceles, CM; Diaz, MS; Escudero, E; Espuny, A; Vicente, MS, 1996) | 0.83 |
| "An in vitro pharmacokinetic model (IVPM) and a mouse model of lethal bacteremia were used to compare the pharmacodynamics of ampicillin-sulbactam when the two components were dosed simultaneously and in sequence against TEM-1-producing Escherichia coli." | ( Efficacy of ampicillin-sulbactam is not dependent upon maintenance of a critical ratio between components: sulbactam pharmacokinetics in pharmacodynamic interactions. Alexov, M; Lister, PD; Sanders, CC, 1996) | 0.88 |
| "Some pharmacokinetic parameters of an ampicillin/sulbactam (2:1) combination were studied in six goats, after intravenous and intramuscular injection at a single dosage of 20 mg/kg bodyweight (13." | ( Some pharmacokinetic parameters of ampicillin/sulbactam combination after intravenous and intramuscular administration to goats. Carceles, CM; Escudero, E; Espuny, A; Vicente, MS, 1996) | 0.84 |
| " Pharmacokinetic parameters obtained with free drug were not significantly different between genders." | ( Pharmacokinetic evaluation of liposomal encapsulated ampicillin in male and female rats. Pardue, RL; White, CA, 1997) | 0.55 |
| " Studies in animals, in vitro models, and pharmacokinetic considerations indicate that a change in the MIC breakpoint for ampicillin/sulbactam should be considered." | ( Microbiologic and pharmacodynamic principals applied to the antimicrobial susceptibility testing of ampicillin/sulbactam: analysis of the correlations between in vitro test results and clinical response. Dudley, MN; Jones, RN, 1997) | 0.72 |
| " The three beta-lactams were rapidly distributed into the different tissues and their pharmacokinetic profiles were found to be very similar." | ( Pharmacokinetics of ampicillin, sulbactam and cefotiam in patients undergoing orthopedic surgery. Dahmen, G; Göbel, C; Gotthardt, H; Gruber, H; Hille, E; Mallwitz, J; Pfaff, G; Wildfeuer, A, ) | 0.45 |
| " The pharmacokinetic parameters were described by a two-compartment open model." | ( Comparative pharmacokinetics of ampicillin trihydrate, gentamicin sulphate and oxytetracycline hydrochloride in Nubian goats and desert sheep. Ali, BH; Elsheikh, HA; Osman, IA, 1997) | 0.58 |
| " The half-life of SDM was increased from 15." | ( Pharmacokinetics of ampicillin and sulfadimidine in pigs infected experimentally with Streptococcus suum. Miao, XQ; Yin, YH; Yuan, ZH, 1997) | 0.62 |
| "5 per cent loss in bodyweight, produced no significant effects on the pharmacokinetic parameters of the drug." | ( Pharmacokinetics of ampicillin trihydrate following intravenous administration to water deprived Nubian goats. Abdullah, AS; Elsheikh, HA; Osman Intisar, AM, ) | 0.45 |
| " Both drugs had a similar pharmacokinetic behavior after intramuscular administration in sheep." | ( Pharmacokinetics of an ampicillin-sulbactam combination after intravenous and intramuscular administration to sheep. Cárceles, CM; Escudero, E; Espuny, A; Vicente, S, 1999) | 0.61 |
| "We compared the pharmacodynamic activities of vancomycin and ampicillin with or without gentamicin once daily or thrice daily in an in vitro infection model with fibrin-platelet clots (FPCs) infected with Enterococcus faecalis." | ( Pharmacodynamics of vancomycin and ampicillin alone and in combination with gentamicin once daily or thrice daily against Enterococcus faecalis in an in vitro infection model. Houlihan, HH; Rybak, MJ; Stokes, DP, 2000) | 0.83 |
| " No changes in elimination half-life relative to a normal population occurred with cefuroxime, cefotiam, and ampicillin." | ( Pharmacokinetics of antibiotic prophylaxis in major orthopedic surgery and blood-saving techniques. Dehne, MG; Hempelmann, G; Mühling, J; Nopens, H; Sablotzki, A, 2001) | 0.52 |
| " The plasma concentration-time curves were analysed by compartmental pharmacokinetic and noncompartmental methods." | ( Pharmacokinetics of an ampicillin/sulbactam (2:1) combination in rabbits. Cárceles, CM; Escudero, E; Serrano, JM; Vicente, MS, 2002) | 0.63 |
| " This work examines the mechanism involved in intestinal elimination of ABZSO and their pharmacokinetic consequences in rat and sheep." | ( Intestinal elimination of albendazole sulfoxide: pharmacokinetic effects of inhibitors. Alvarez, AI; García, JL; Merino, G; Molina, AJ; Prieto, JG; Pulido, MM, 2003) | 0.32 |
| "To investigate the feasibility of using multivariate cluster analysis to meta-analyze pharmacokinetic data obtained from studies of pharmacokinetics of ampicillin trihydrate in cattle and identify factors that could account for variability in pharmacokinetic parameters among studies." | ( Multivariate meta-analysis of pharmacokinetic studies of ampicillin trihydrate in cattle. Baynes, RE; Craigmill, AL; Gehring, R; Pierce, AN; Riviere, JE; van der Merwe, D, 2005) | 0.77 |
| " Noncompartmental pharmacokinetic analyses were performed, and values of pharmacokinetic parameters were clustered by use of multivariate cluster analysis." | ( Multivariate meta-analysis of pharmacokinetic studies of ampicillin trihydrate in cattle. Baynes, RE; Craigmill, AL; Gehring, R; Pierce, AN; Riviere, JE; van der Merwe, D, 2005) | 0.57 |
| "Meta-analysis was successful in detecting a potential subpopulation of cattle for which factors that explained differences in pharmacokinetic parameters could be identified." | ( Multivariate meta-analysis of pharmacokinetic studies of ampicillin trihydrate in cattle. Baynes, RE; Craigmill, AL; Gehring, R; Pierce, AN; Riviere, JE; van der Merwe, D, 2005) | 0.57 |
| "Using an in vitro pharmacodynamic model, a multidrug-resistant strain of Acinetobacter baumannii was exposed to colistin methanesulfonate alone and in combination with ceftazidime." | ( Colistin methanesulfonate against multidrug-resistant Acinetobacter baumannii in an in vitro pharmacodynamic model. Hovde, LB; Kroeger, LA; Mitropoulos, IF; Rotschafer, JC; Schafer, J, 2007) | 0.34 |
| " The pharmacokinetics of penicillin G were best described by a two-compartment pharmacokinetic model." | ( Pharmacokinetics of penicillin G in infants with a gestational age of less than 32 weeks. Bult, Y; Danhof, M; DeJongh, J; Goessens, WH; Mouton, JW; Muller, AE; van den Anker, JN, 2007) | 0.34 |
| " pharmacokinetic data on 670 drugs representing, to our knowledge, the largest publicly available set of human clinical pharmacokinetic data." | ( Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Lombardo, F; Obach, RS; Waters, NJ, 2008) | 0.35 |
| "The aim of this study was to assess and compare the pharmacokinetic (PK) properties, bioavailability, and bioequivalence of a newly developed dispersible tablet formulation (test) of ampicillin/ probenecid with those of an established branded capsule formulation (reference) in healthy Chinese male volunteers." | ( Pharmacokinetic properties and bioequivalence of two compound formulations of 1500 mg ampicillin (1167 mg)/probenecid (333 mg): a randomized-sequence, single-dose, open-label, two-period crossover study in healthy Chinese male volunteers. Feng, W; Liu, M; Wang, S; Wei, M; Wu, H; Yao, W; Zhao, H, 2010) | 0.78 |
| " The efficacies of simulated pharmacokinetic profiles for human 10-day clinical regimens of ampicillin, meropenem, moxifloxacin, ciprofloxacin, and gentamicin were compared with the gold standard, streptomycin, for killing of Yersinia pestis in an in vitro pharmacodynamic model." | ( Comparative efficacies of candidate antibiotics against Yersinia pestis in an in vitro pharmacodynamic model. Brown, D; Drusano, GL; Heine, HS; Kulawy, R; Liu, W; Louie, A; Vanscoy, B, 2011) | 0.59 |
| "Twelve critically ill patients with anuric AKI being treated with ED were enrolled in a prospective, open-label, observational pharmacokinetic study." | ( Pharmacokinetics of ampicillin/sulbactam in critically ill patients with acute kidney injury undergoing extended dialysis. Broll, M; Burhenne, H; Burkhardt, O; Clajus, C; Hafer, C; Kaever, V; Kielstein, JT; Knitsch, W; Lorenzen, JM, 2012) | 0.7 |
| " Plasma concentrations of ampicillin were simulated with the pharmacokinetic parameters obtained." | ( Pharmacokinetics of ampicillin-sulbactam and the renal function-based optimization of dosing regimens for prophylaxis in patients undergoing cardiovascular surgery. Iguro, Y; Ikawa, K; Imoto, Y; Ishida, S; Matsumoto, K; Morikawa, N; Okano, Y; Shimodozono, Y; Takeda, Y; Watanabe, E; Yamada, K; Yamamoto, H; Yokoyama, Y, 2012) | 1 |
| " baumannii using an in vitro pharmacodynamic model." | ( In vitro pharmacodynamics of human-simulated exposures of ampicillin/sulbactam, doripenem and tigecycline alone and in combination against multidrug-resistant Acinetobacter baumannii. Hagihara, M; Housman, ST; Kuti, JL; Nicolau, DP, 2013) | 0.63 |
| "The aims of this study were to develop a population pharmacokinetic (PK) model of ampicillin and sulbactam, to identify patient characteristics influencing the PK, and to explore the relationship between dose regimen and degree of renal impairment with exposure and time above minimum inhibitory concentration (MIC)." | ( Population pharmacokinetics of ampicillin and sulbactam in patients with community-acquired pneumonia: evaluation of the impact of renal impairment. Marshall, S; Muto, C; Shoji, S; Soto, E; Tomono, Y, 2014) | 0.91 |
| "Although ampicillin is the most commonly used drug in neonates, developmental pharmacokinetic (PK) data to guide dosing are lacking." | ( Characterization of the population pharmacokinetics of ampicillin in neonates using an opportunistic study design. Benjamin, DK; Capparelli, EV; Cohen-Wolkowiez, M; Delmore, P; Gao, J; Ian-U Chong, S; Laughon, M; Le, J; Melloni, C; Poindexter, B; Salgado, A; Sullivan, JE; Tremoulet, A, 2014) | 1.07 |
| " The peak concentration of serum ABPC was 83." | ( Enterococcal endocarditis complicated with ruptured infected-intracranial aneurysm: with pharmacokinetic-pharmacodynamic documentation in proof of the successful antimicrobial treatment. Aoki, Y; Hamada, Y; Magarihuchi, H; Urakami, T; Yamakuchi, H, 2014) | 0.4 |
| " Drug exposure was expressed as the ratio of the area under the concentration-time curve for the free, unbound fraction of the drug to the MIC (fAUC/MIC) (VAN) or the time in a 24-h period that the drug concentration for the free, unbound fraction exceeded the MIC under steady-state pharmacokinetic conditions (fT(>MIC)) (SAM and TZP) and linked to the change in log10 CFU/thigh." | ( An optimized mouse thigh infection model for enterococci and its impact on antimicrobial pharmacodynamics. Agudelo, M; Gonzalez, JM; Rodriguez, CA; Vesga, O; Zuluaga, AF, 2015) | 0.42 |
| " An increasing number of dairy farms are milking 3 times per day (instead of the traditional 2 times per day) and very little pharmacokinetic data exists on the use of intramammary drugs in a 3×system." | ( Short communication: Pharmacokinetics of intramammary hetacillin in dairy cattle milked 3 times per day. Baynes, RE; Lindquist, DA; Smith, GW, 2015) | 0.42 |
| " Pharmacokinetic parameters were estimated and used to predict the free plasma concentrations of ampicillin." | ( Pharmacokinetics of Prophylactic Ampicillin-Sulbactam and Dosing Optimization in Patients Undergoing Cardiovascular Surgery with Cardiopulmonary Bypass. Ikawa, K; Imoto, Y; Matsumoto, K; Morikawa, N; Takeda, Y; Watanabe, E; Yamamoto, H; Yokoyama, Y, 2015) | 0.92 |
| " Pharmacokinetic parameters were estimated and used to predict the free plasma concentrations of ampicillin and sulbactam." | ( The pharmacokinetics of ampicillin-sulbactam in anuric patients: dosing optimization for prophylaxis during cardiovascular surgery. Ikawa, K; Imoto, Y; Matsumoto, K; Morikawa, N; Takeda, Y; Watanabe, E; Yamamoto, H; Yokoyama, Y, 2016) | 0.96 |
| " Modern pediatric pharmacokinetic study protocols frequently favor opportunistic, "scavenged" sampling." | ( Development of a Novel Multipenicillin Assay and Assessment of the Impact of Analyte Degradation: Lessons for Scavenged Sampling in Antimicrobial Pharmacokinetic Study Design. Barker, CIS; Johnston, A; Kipper, K; Sharland, M; Standing, JF, 2018) | 0.48 |
| "Dried blood spot (DBS) is a practical sampling strategy for pharmacokinetic studies in neonates." | ( Comparative Analysis of Ampicillin Plasma and Dried Blood Spot Pharmacokinetics in Neonates. Benjamin, DK; Blackford, M; Boakye-Agyeman, F; Cohen-Wolkowiez, M; Delmore, P; Harper, B; James, LP; Laughon, M; Le, J; Melloni, C; Mitchell, J; Poindexter, B; Sullivan, JE; Yogev, R, 2018) | 0.79 |
| "We identified infants <28 days of age with Escherichia coli, Enterococcus or Streptococcus agalactiae (group B streptococcus) bloodstream infections from 1997 to 2012 and previously included in an ampicillin pharmacokinetic (PK) modeling study." | ( Paradoxical Antibiotic Effect of Ampicillin: Use of a Population Pharmacokinetic Model to Evaluate a Clinical Correlate of the Eagle Effect in Infants With Bacteremia. Benjamin, DK; Clark, RH; Cohen-Wolkowiez, M; Ericson, JE; Greenberg, RG; Hornik, CP; Le, J; Smith, PB; Tremoulet, AH, 2020) | 1.03 |
| " The optimized mouse infection model allowed to obtain the complete dose-response curve of AMP+CRO and to define its interaction based on pharmacodynamic parameter changes." | ( A new pharmacodynamic approach to study antibiotic combinations against enterococci in vivo: Application to ampicillin plus ceftriaxone. Jimenez-Toro, I; Otalvaro, JD; Rodriguez, CA; Vesga, O; Zuluaga, AF, 2020) | 0.77 |
| " Blood samples were obtained at timed intervals (just before administration, 1, 2, 4, 12, and 24 hours), analyzed using high-pressure liquid chromatography followed by pharmacokinetic analysis of the plasma drug concentrations." | ( Ampicillin pharmacokinetics in azotemic and healthy dogs. Labato, MA; Monaghan, KN; Papich, MG, 2021) | 2.06 |
| " Noncompartmental anaysis (NCA) and population pharmacokinetic (pop-PK) modeling were performed and probability of therapeutic target attainment was simulated." | ( Ampicillin Pharmacokinetics During First Week of Life in Preterm and Term Neonates. Hallik, M; Herodes, K; Ilmoja, ML; Kipper, K; Lutsar, I; Metsvaht, T; Oselin, K; Padari, H; Soeorg, H; Tasa, T, 2021) | 2.06 |
| "We aimed to develop population pharmacokinetic (PK) models of ampicillin and sulbactam using pooled data analysis and to optimize dosing regimens of ampicillin-sulbactam (combination ratio of 2:1) in pediatric patients." | ( Pharmacodynamic Evaluation of Ampicillin-sulbactam in Pediatric Patients Using Plasma and Urine Data. Ikawa, K; Ishihara, N; Morikawa, N; Naora, K; Onita, T; Tamaki, H; Yano, T, 2022) | 1.25 |
| " Based on these models, we estimated the probability of attaining a pharmacodynamic (PD) target [50% of time that free drug concentrations above the minimum inhibitory concentration, 50% fT > minimum inhibitory concentration (MIC)] against MIC90 [MIC that blocked the growth of 90% of the strains] of common bacteria in community-acquired pneumonia." | ( Pharmacodynamic Evaluation of Ampicillin-sulbactam in Pediatric Patients Using Plasma and Urine Data. Ikawa, K; Ishihara, N; Morikawa, N; Naora, K; Onita, T; Tamaki, H; Yano, T, 2022) | 1.01 |
| "The aim of this pharmacokinetic study was to describe and quantify population pharmacokinetics of three antibiotics, cefazolin, ampicillin, and ciprofloxacin, used as antibacterial prophylaxis during cardiovascular surgery with the use of extracorporeal circulation (ECC)." | ( Population pharmacokinetics of three alternative prophylactic antibiotics during cardiac surgery with extracorporeal circulation. Kubickova, V; Santavy, P; Sima, M; Urbanek, K, 2023) | 1.12 |
| "Adult patients undergoing cardiac surgery with ECC were enrolled to this prospective, pharmacokinetic study." | ( Population pharmacokinetics of three alternative prophylactic antibiotics during cardiac surgery with extracorporeal circulation. Kubickova, V; Santavy, P; Sima, M; Urbanek, K, 2023) | 0.91 |
| " For all antibiotics, population pharmacokinetic models have been successfully developed." | ( Population pharmacokinetics of three alternative prophylactic antibiotics during cardiac surgery with extracorporeal circulation. Kubickova, V; Santavy, P; Sima, M; Urbanek, K, 2023) | 0.91 |
| " Pharmacokinetic data to guide ampicillin dosing in neonates and during the intrapartum period are limited." | ( Foetal and neonatal exposure prediction and dosing evaluation for ampicillin using a physiologically-based pharmacokinetic modelling approach. Li, S; Xie, F, 2023) | 1.43 |
| "The pharmacokinetic variability of ampicillin-sulbactam in adults has not been extensively described, particularly in patients with a reduced renal function (i." | ( Population Pharmacokinetics and Dosing Simulations of Ampicillin and Sulbactam in Hospitalised Adult Patients. Abdul-Aziz, MH; Cotta, MO; Lukas, DL; Parker, S; Roberts, JA; Setiawan, E; Sosilya, H; Wallis, SC; Widjanarko, D, 2023) | 1.44 |
| " While ampicillin is the preferred agent for the treatment of susceptible Enterococcus faecalis infections, there are no in vivo pharmacokinetic studies regarding ampicillin dosing in patients receiving ECMO." | ( Pharmacokinetics of ampicillin during venovenous extracorporeal membrane oxygenation: A case report. Drummond, W; Elbarbry, F; Footer, BW; Kim, S; Stucky, NL, 2023) | 1.69 |
This investigation used checkerboard and time-kill assays to evaluate the in vitro activity of RPR 106972. It was found that the use of these nanoparticles in combination with a magnetic field accelerated wound healing and reduced the titer of microorganisms.
| Excerpt | Reference | Relevance |
|---|---|---|
| " The combination of ampicillin or cefazolin with mecillinam leads to bactericidal acceleration; the effects are comparable to those of the combination with gentamycin." | ( [Effects of ampicillin and cefazolin combined with mecillinam (author's transl)]. Bischof-Léger, E; Helm, EB; Stille, W, 1978) | 0.96 |
| "5 g orally) in combination with 1 g of probenecid (instant therapy)." | ( Treatment of urogenital/rectal gonorrhoea in males and females with epicillin in combination with probenecid. de Koning, GA; Michel, MF; Schuller, JL; Stolz, E, 1978) | 0.26 |
| "05 mg/g) alone or in combination with one dose of dexamethasone (0." | ( Effect of dexamethasone or HWA-138 in combination with antibiotics in experimental Haemophilus influenzae type b infection. Hawkins, EP; Kaplan, SL; Mason, EO; Rodriguez, AF, 1991) | 0.28 |
| "Fifteen strains of Enterococcus faecalis, all clinical blood culture isolates from patients with endocarditis, were studied by kill-kinetic experiments using penicillin G, ampicillin and amoxicillin alone and in combination with tobramycin." | ( Bactericidal effect of penicillin, ampicillin, and amoxicillin alone and in combination with tobramycin against Enterococcus faecalis as determined by kill-kinetic studies. Frimodt-Møller, N; Gutschik, E; Westh, H, ) | 0.6 |
| " Preclinical research provides additional evidence that viruses and chemicals may interact and produce illnesses in animals." | ( Adverse virus-drug interactions. Amsel, Z; Drotman, DP; Haverkos, HW, ) | 0.13 |
| "IPM in combination with ABPC produced synergistic effects against MRSA." | ( [Antibacterial activity of imipenem in combination with ampicillin against methicillin-resistant strains of Staphylococcus aureus]. Inoue, K; Kobayashi, I; Miyake, N; Saionji, K; Shitara, M, 1990) | 0.53 |
| "Efficacy of the ceftazidime monotherapy in 120 febrile children with neoplastic diseases and granulocytopenia was compared with that of tobramycin combined with amoxycillin/ampicillin." | ( [Assessment of the efficacy of treating infections in hematopoietic proliferative diseases: Monotherapy with ceftazidime and tobramycin combined with amoxycillin/ampicillin]. Bubała, H; Janik-Moszant, A; Koehler, M; Kuder, K; Sońta-Jakimczyk, D; Wieczorek, M, ) | 0.52 |
| " In comparison with the antibiotic alone, the most marked reductions in the number of resistant strains on combination with sulbactam were as follows (the percentage of reduction is shown in brackets): for SUL + AMP and Acine-tobacter spp." | ( In vitro activity against clinically important gram-positive and gram-negative bacteria of sulbactam, alone and in combination with ampicillin, cefotaxime, mezlocillin, and piperacillin. Schmalreck, AF; Wildfeuer, A, 1990) | 0.48 |
| " With lysozyme used in combination with the antibiotic the immunomorphological zones of the lymph nodes appeared to be preserved and the volumetric proportion of macrophages increased." | ( [Increasing the effectiveness of ampicillin in combination with lysozyme]. Kruglova, IS; Larin, BA; Rastunova, GA; Shcherbakova, EG; Zhuravleva, TP, 1990) | 0.56 |
| " The bactericidal effect obtained with daptomycin in combination with aminoglycosides suggest that further evaluation of these combinations in enterococcal endocarditis could have a clinical interest if this bactericidal effect was confirmed by in vivo studies." | ( [Bactericidal activity of daptomycin and vancomycin alone or in combination with tobramycin, netilmicin or ampicillin against enterococcus]. Cordin, X; Duez, JM; Kazmierczak, A; Péchinot, A; Siébor, E, 1989) | 0.49 |
| " An investigation was therefore carried out to determine whether aztreonam, a synthetic monocyclic beta-lactam antibiotic, can safely be combined with cyclosporin." | ( Aztreonam can safely be used in combination with cyclosporin without aggravating nephrotoxicity. Hoitsma, AJ; Koene, RA; Rietbroek, RC, 1989) | 0.28 |
| "A study was done on cefodizime (THR-221, CDZM) in combination with ampicillin (ABPC) for its transferability to cerebrospinal fluid (CSF) of rabbits with experimental meningitis caused by Staphylococcus aureus." | ( [Experimental study on transferability to cerebrospinal fluid of cefodizime in combination with ampicillin]. Haruta, T; Kobayashi, Y; Okura, K, 1989) | 0.73 |
| "Seven strains of Streptococcus faecalis, of which two possessed high-level resistance to streptomycin (MIC greater than or equal to 2000 mcg/ml), and two strains of Streptococcus faecium were evaluated with respect to killing-effect and duration of post-antibiotic effect (PAE) of ampicillin and vancomycin in combination with streptomycin, gentamicin, tobramycin and netilmicin." | ( Evaluation of the combination effects of ampicillin or vancomycin combined with streptomycin, gentamicin, tobramycin or netilmicin against enterococci. Fuursted, K, 1989) | 0.72 |
| "The in vitro synergistic activities of the beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam, combined with ampicillin, ticarcillin, mezlocillin, azlocillin, piperacillin, and apalcillin, were determined against 34 strains of members of the Enterobacteriaceae family, Pseudomonas aeruginosa, Aeromonas hydrophila, and Haemophilus influenzae with characterized plasmid or chromosomal beta-lactamases or both." | ( Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam combined with ampicillin and broad-spectrum penicillins against defined beta-lactamase-producing aerobic gram-negative bacilli. Aronoff, SC; Jacobs, MR; Johenning, S; Shlaes, DM; Yamabe, S, 1986) | 0.69 |
| "The in-vitro synergistic activity of YTR 830, a new beta-lactamase inhibitor, combined with four extended-spectrum penicillins (ticarcillin, piperacillin, mezlocillin and apalcillin) against ticarcillin-resistant clinical isolates of Gram-negative enteric bacilli was compared with that of clavulanate and sulbactam." | ( Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate and sulbactam combined with extended-spectrum penicillins against ticarcillin-resistant Enterobacteriaceae and pseudomonads. Aronoff, SC; Jacobs, MR; Johenning, S; Yamabe, S, 1986) | 0.27 |
| "The in-vitro activity of a beta-lactamase inhibitor (clavulanic acid, sulbactam, BL-P2013 or BL-P2090) in combination with ampicillin against 13 isolates of Mycobacterium tuberculosis was determined by broth dilution." | ( Comparison of four beta-lactamase inhibitors in combination with ampicillin against Mycobacterium tuberculosis. Cynamon, MH; Sorg, TB, 1987) | 0.72 |
| "The antibacterial activity of ampicillin against Enterobacteriaceae strongly increased when combined with 6 beta-bromopenicillanic acid (BPA) or clavulanic acid (CA)." | ( In vitro activity of ampicillin alone and in combination with different concentrations of 6 beta-bromopenicillanic acid, clavulanic acid and mecillinam. Houben, AW; Stobberingh, EE; van Boven, CP, 1987) | 0.88 |
| "Several in vitro parameters of sulbactam combined with ampicillin (Sbt/Amp) were studied in order to evaluate and compare its microbiological properties with those of beta-lactamase stable beta-lactams (ceftriaxone, cefamandole, cefoxitin)." | ( Microbiological properties of sulbactam combined with ampicillin. Barba, D; Esposito, S; Galante, D; Ruffilli, MP, 1987) | 0.77 |
| "Imipenem was evaluated for its in vitro and in vivo activities alone and in combination with gentamicin against a clinical isolate of Listeria monocytogenes, and the results were compared with the activities of ampicillin with and without gentamicin." | ( In vitro and in vivo studies of imipenem-cilastatin alone and in combination with gentamicin against Listeria monocytogenes. Kim, KS, 1986) | 0.46 |
| "Amdinocillin alone and in combination with other beta-lactam antibiotics was tested for in vitro activity against aminoglycoside-susceptible and resistant gram-negative bacteria." | ( In vitro activity of amdinocillin in combination with other beta-lactam antibiotics against aminoglycoside-susceptible and resistant gram-negative bacteria. Gibson, G; Nachamkin, I; Samel, C; Sawyer, K; Skalina, D, 1988) | 0.27 |
| " The findings indicate that antibiotic disks used routinely in the clinical laboratory can be used in a simple elution test to determine susceptibility of organisms to beta-lactam antibiotics alone and in combination with amdinocillin." | ( Collaborative clinical laboratory study of a broth-disk test for determination of bacterial susceptibility to beta-lactams in combination with amdinocillin. Barry, AL; Beskid, G; Cleeland, R; Fallat, V; Isenberg, HD; Murray, PR; Pierson, C; Squires, E; Tilton, RC, 1987) | 0.27 |
| "Penicillinate sulphone beta-lactamase inhibitors, sulbactam, and BL-P2013, were very effective alone and in combination with ampicillin-like penicillins against 34 strains of Legionellae." | ( The in vitro activity of sulphones alone and in combination with ampicillin or amoxicillin against Legionella pneumophila and other Legionella spp. including beta-lactamase studies. Jones, RN; McDougal, LK; Thornsberry, C; Wilson, HW, 1985) | 0.71 |
| " At achievable serum concentrations, ampicillin alone killed 60% of strains, whereas combination with streptomycin increased this to 90% and with gentamicin to 100%." | ( In vitro activity of ampicillin or vancomycin combined with gentamicin or streptomycin against enterococci. Guze, LB; Harwick, HJ; Kalmanson, GM, 1973) | 0.84 |
| "Fifty out of 100 patients with typhoid fever, matched for age, stage of illness, and degree of fever, were treated with chloramphenicol and the other 50 were treated with chloramphenicol combined with ampicillin." | ( Chloramphenicol combined with ampicillin in treatment of typhoid. De Ritis, F; Giammanco, G; Manzillo, G, 1972) | 0.73 |
| " Combined with amoxicillin, YTR 830 is a potentially useful agent for therapy of many bacterial infections." | ( Comparative activities of the beta-lactamase inhibitors YTR 830, sodium clavulanate, and sulbactam combined with amoxicillin or ampicillin. Aronoff, SC; Jacobs, MR; Johenning, S; Yamabe, S, 1984) | 0.47 |
| " Killing curves showed that vancomycin and teicoplanin were bacteriostatic and that synergy was achieved when each was combined with gentamicin." | ( The activity of vancomycin and teicoplanin alone and in combination with gentamicin or ampicillin against Streptococcus faecalis. Chen, HY; Williams, JD, 1984) | 0.49 |
| "The activities of moxalactam and cefotaxime, alone and combined with ampicillin or penicillin, against 40 isolates of group B streptococci were assessed by using the microtiter broth dilution, checkerboard, and time-kill techniques." | ( Activity of moxalactam and cefotaxime alone and in combination with ampicillin or penicillin against group B streptococci. Cherubin, CE; Corrado, ML; Landesman, SH; Sierra, MF, 1981) | 0.73 |
| "The results of three separate studies aimed at evaluating the efficacy of long-term, low-dose treatment with pivmecillinam alone, and in combination with pivampicillin, in patients prone to recurrent bacteriuria, are presented." | ( Long-term, low-dose treatment with pivmecillinam alone and in combination with pivampicillin in patients prone to recurrent bacteriuria. Barclay, RP; Mejlhede, A; Nilsson, LB, 1982) | 0.69 |
| " This observation suggests that a new and extremely active cephalosporin is as effective in vivo when used alone as when given in combination with an aminoglucoside and provides rationale for testing the use of single antibiotic therapy for clinical situations for which combinations of antibiotics are currently recommended." | ( Treatment of experimental ascending Escherichia coli pyelonephritis with ceftriaxone alone and in combination with gentamicin. Glauser, MP, 1982) | 0.26 |
| "3 patients with salmonella infections who continued to excrete salmonella in fecal samples for more than 6 months were treated with pivmecillinam alone or in combination with pivampicillin." | ( Treatment of Salmonella carriers with pivmecillinam alone or in combination with pivampicillin: experience with three patients. Bruun, JN; Bøe, J; Digranes, A; Maeland, A, 1983) | 0.68 |
| "The in vitro and in vivo activities of mezlocillin and ampicillin, alone and in combination with gentamicin, against Streptococcus faecalis were compared." | ( Comparative efficacies of mezlocillin and ampicillin alone or in combination with gentamicin in the treatment of Streptococcus faecalis endocarditis in rabbits. Fass, RJ; Wright, CA, 1984) | 0.78 |
| " Patients in Group 1 received either a single intravenous dose of 1500 mg metronidazole or this dose was combined with a single, intravenous dose of 6 g ampicillin." | ( Prophylactic regimens in colorectal surgery. Comparison between metronidazole used alone or in combination with either ampicillin or doxycycline. Andenaes, K; Bergan, T; Bjerkeset, T; Brabrand, G; Erichsen, H; Flørenes, T; Garberg, O; Glauer, H; Holter, O; Roland, M, 1984) | 0.67 |
| "Since the optimal antimicrobial therapy for infections caused by Listeria monocytogenes, particularly in patients allergic to penicillin, is uncertain, we investigated the in vitro effects of erythromycin, alone and in combination with other antibiotics, on listeriae." | ( Effects of erythromycin in combination with penicillin, ampicillin, or gentamicin on the growth of Listeria monocytogenes. Penn, RL; Steigbigel, RT; Ward, TT, 1982) | 0.51 |
| "The phosphonopeptide alafosfalin (L-alanyl-L-1-aminoethylphosphonic acid) exhibited synergy in vitro and in animal studies against a range of bacterial genera when combined with cephalexin." | ( Antibacterial properties of alafosfalin combined with cephalexin. Atherton, FR; Hall, MJ; Hassall, CH; Holmes, SW; Lambert, RW; Lloyd, WJ; Nisbet, LJ; Ringrose, PS; Westmacott, D, 1981) | 0.26 |
| "The activity of piperacillin/tazobactam, ampicillin/sulbactam, imipenem and nafcillin alone and in combination with vancomycin was compared with vancomycin monotherapy against MRSA in test-tube time-kill studies and in infected fibrin clots." | ( An evaluation of the bactericidal activity of ampicillin/sulbactam, piperacillin/tazobactam, imipenem or nafcillin alone and in combination with vancomycin against methicillin-resistant Staphylococcus aureus (MRSA) in time-kill curves with infected fibrin Palmer, SM; Rybak, MJ, 1997) | 0.82 |
| "Using a checkerboard assay, ampicillin, vancomycin, and RP 59500, each in combination with chloramphenicol, were tested for synergy against 23 isolates of vancomycin-resistant enterococci." | ( In vitro activity of chloramphenicol alone and in combination with vancomycin, ampicillin, or RP 59500 (quinupristin/dalfopristin) against vancomycin-resistant enterococci. Messick, CR; Pendland, SL, 1997) | 0.82 |
| "This investigation used checkerboard and time-kill assays to evaluate the in vitro activity of RPR 106972 (45% pristinamycin IB and 55% pristinamycin IIB) alone and in combination with vancomycin or ampicillin +/- gentamicin against multidrug-resistant enterococci." | ( In vitro activity of RPR 106972 alone and in combination with vancomycin, ampicillin, and gentamicin against multidrug-resistant enterococci. Messick, CR; Pendland, SL; Woodward, J, 1998) | 0.72 |
| "This in vitro study evaluated the activities of vancomycin, LY333328, and teicoplanin alone and in combination with gentamicin, rifampin, and RP59500 against Staphylococcus aureus isolates with intermediate susceptibilities to vancomycin." | ( Evaluation of bactericidal activities of LY333328, vancomycin, teicoplanin, ampicillin-sulbactam, trovafloxacin, and RP59500 alone or in combination with rifampin or gentamicin against different strains of vancomycin-intermediate Staphylococcus aureus by Aeschlimann, JR; Hershberger, E; Moldovan, T; Rybak, MJ, 1999) | 0.53 |
| " Our data suggest that once-daily gentamicin in combination with ampicillin or vancomycin demonstrates equivalent bacterial reductions to combination therapy with thrice-daily gentamicin." | ( Pharmacodynamics of vancomycin and ampicillin alone and in combination with gentamicin once daily or thrice daily against Enterococcus faecalis in an in vitro infection model. Houlihan, HH; Rybak, MJ; Stokes, DP, 2000) | 0.82 |
| "This study tests the usefulness of ceftriaxone combined with ampicillin as an alternative to ampicillin plus gentamicin for the treatment of experimental endocarditis due to Enterococcus faecalis without high-level resistance to aminoglycosides." | ( Efficacy of ampicillin combined with ceftriaxone and gentamicin in the treatment of experimental endocarditis due to Enterococcus faecalis with no high-level resistance to aminoglycosides. Crespo, M; Gavaldá, J; Gómez, MT; Gomis, X; Len, O; Onrubia, PL; Pahissa, A; Ramírez, JL; Rodríguez, D; Ruíz, I, 2003) | 0.94 |
| " faecalis and were treated for 3 days with ampicillin 2 g every 4 h administered as 'human-like' (H-L) pharmacokinetics, plus gentamicin 1 mg/kg every 8 h H-L, or ceftriaxone 2 g every 12 h H-L alone or combined with gentamicin 6 mg/kg every 24 h administered subcutaneously." | ( Efficacy of ampicillin combined with ceftriaxone and gentamicin in the treatment of experimental endocarditis due to Enterococcus faecalis with no high-level resistance to aminoglycosides. Crespo, M; Gavaldá, J; Gómez, MT; Gomis, X; Len, O; Onrubia, PL; Pahissa, A; Ramírez, JL; Rodríguez, D; Ruíz, I, 2003) | 0.96 |
| "The in vitro antibacterial activity against antibiotic-resistant Propionibacterium acnes of kaempferol isolated from the Impatiens balsamina alone and in combination with erythromycin or clindamycin antibiotics was investigated." | ( In vitro activity of kaempferol isolated from the Impatiens balsamina alone and in combination with erythromycin or clindamycin against Propionibacterium acnes. Kim, IH; Lim, YH; Seo, JJ, 2007) | 0.34 |
| "A new method orthogonal projection to latent structures (O-PLS) combined with artificial neural networks is investigated for non-destructive determination of Ampicillin powder via near-infrared (NIR) spectroscopy." | ( Orthogonal projection to latent structures combined with artificial neural networks in non-destructive analysis of Ampicillin powder. Fei, Q; Liu, G; Ren, Y; Wang, B; Zuo, Y, 2009) | 0.76 |
| " aureus (four MRSA and two GISA) and four strains of enterococci (two Enterococcus faecalis and two Enterococcus faecium) were serially exposed in broth to two-fold stepwise increasing concentrations of daptomycin alone or in combination with a fixed concentration [0." | ( In vitro prevention of the emergence of daptomycin resistance in Staphylococcus aureus and enterococci following combination with amoxicillin/clavulanic acid or ampicillin. Entenza, JM; Giddey, M; Moreillon, P; Vouillamoz, J, 2010) | 0.56 |
| " From those results we performed the checkerboard test to determine the synergism of EM in combination with ampicillin (AM) or oxacillin (OX) against all strains." | ( Synergistic effect of emodin in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus. Choi, JG; Jeong, GS; Kang, OH; Keum, JH; Kim, SB; Kim, YC; Kwon, DY; Lee, YS; Oh, YC; Shin, DW, 2010) | 0.83 |
| " In the present study, we firstly found that artesunate in combination with oxacillin was capable of protecting mice challenged with live MRSA WHO-2 (WHO-2) and the protection was related to the reduced TNF-α and IL-6 levels and decreased bacterial load." | ( Artesunate in combination with oxacillin protect sepsis model mice challenged with lethal live methicillin-resistant Staphylococcus aureus (MRSA) via its inhibition on proinflammatory cytokines release and enhancement on antibacterial activity of oxacilli Cao, H; Cen, Y; Jiang, W; Li, B; Li, J; Liu, X; Pan, X; Zheng, J; Zheng, X; Zhou, H, 2011) | 0.37 |
| "We report a case of postsurgical meningitis caused by multiresistant Acinetobacter baumannii successfully treated with high doses of ampicillin/sulbactam combined with rifampicin and fosfomycin." | ( Postsurgical meningitis due to multiresistant Acinetobacter baumannii successfully treated with high doses of ampicillin/sulbactam combined with rifampicin and fosfomycin. Clec'h, C; Cohen, Y; Jauréguy, F; Mellon, G; Picard, B, 2012) | 0.79 |
| "The in vitro activity of mastoparan-AF, an amphipathic antimicrobial peptide isolated from the hornet venom of Vespa affinis, alone and in combination with various clinically used antibiotics, was investigated against 21 Escherichia coli isolates/strains." | ( In vitro activity of mastoparan-AF alone and in combination with clinically used antibiotics against multiple-antibiotic-resistant Escherichia coli isolates from animals. Hou, RF; Lin, CF; Lin, CH; Shia, WY; Shyu, CL; Tu, WC, 2012) | 0.38 |
| "Effects of ampicillin (Amp) in combination with riboflavin on septic arthritis in mice infected with Staphylococcus aureus have been reported." | ( Ampicillin alone and in combination with riboflavin modulates Staphylococcus aureus infection induced septic arthritis in mice. Bandyopadhyay, D; Bishayi, B; Dutta, K; Ghosh, D; Mal, P, 2012) | 2.21 |
| "5-4) results against the bacterium in combination with ampicillin, ciprofloxacin, tetracycline or metronidazole." | ( In vitro effects of N-acetyl cysteine alone and in combination with antibiotics on Prevotella intermedia. Jang, EY; Lee, JY; Moon, JH; Shim, KS, 2015) | 0.66 |
| " This study systematically evaluated by in vitro time-kill studies the effect of daptomycin in combination with ampicillin, cefazolin, ceftriaxone, ceftaroline, ertapenem, gentamicin, tigecycline, and rifampin, for a collection of 9 daptomycin-NS enterococci that exhibited a broad range of MICs and different resistance-conferring mutations." | ( In vitro activity of daptomycin in combination with β-lactams, gentamicin, rifampin, and tigecycline against daptomycin-nonsusceptible enterococci. Carvalho, M; Charlton, CL; Hindler, JA; Humphries, R; Kelesidis, T; Miller, SA; Nizet, V; Nonejuie, P; Pogliano, J; Sakoulas, G; Wong-Beringer, A, 2015) | 0.63 |
| " In this study, the possibility of drug-drug interactions between amlodipine and coadministered antibiotics (ampicillin) was investigated in rats; thus, changes in the metabolic activities of gut microflora and the consequent pharmacokinetic pattern of amlodipine following ampicillin treatment were characterized." | ( Effects of orally administered antibiotics on the bioavailability of amlodipine: gut microbiota-mediated drug interaction. Kim, DH; Kim, IS; Yoo, DH; Yoo, HH, 2016) | 0.65 |
| " Killing kinetics were determined at 2-h intervals from 0 to 6 h after exposure to ampicillin (AMP) or cefotaxime (CTX) combined with GM." | ( Enhancement of bactericidal activity against group B streptococci with reduced penicillin susceptibility by uptake of gentamicin into cells resulting from combination with β-lactam antibiotics. Ebara, Y; Iwata, S; Moritoki, N; Morozumi, M; Murata, M; Sato, M; Takata, M; Toyofuku, M; Ubukata, K, 2017) | 0.68 |
| " It was found that the use of these nanoparticles in combination with a magnetic field accelerated wound healing and reduced the titer of microorganisms in comparison with the corresponding parameters in the untreated animals and animals treated with nanoparticles or ampicillin alone." | ( Efficiency of Ampicillin-Associated Biogenic Ferrihydrite Nanoparticles in Combination with a Magnetic Field for Local Treatment of Burns. Boldyreva, AV; Dobretsov, KG; Inzhevatkin, EV; Kolenchukova, OA; Ladygina, VP; Stolyar, SV, 2020) | 1.1 |
| " faecium with monotherapy or its combination with daptomycin by time-killing assay." | ( In vitro activities of thiazolidione derivatives combined with daptomycin against clinical Enterococcus faecium strains. Chen, J; Chen, Z; Deng, Q; Qu, D; Tang, Y; Wu, Y; Xiong, Y; Yu, Z; Zhao, Y; Zheng, J, 2022) | 0.72 |
| "The lack of rationality evaluation method for drug combination has long restricted its clinical application." | ( [Rationality evaluation of Shuanghuanglian Injection combined with Ampicillin Sodium for Injection based on sequential analysis]. Huang, MY; Li, JL; Liu, S; Liu, XW; Wang, AT; Wang, ZZ; Xu, Y; Yan, D, 2022) | 0.96 |
| "Evaluate the in vivo efficacy and resistance prevention of cefiderocol in combination with ceftazidime/avibactam, ampicillin/sulbactam and meropenem using human-simulated regimens (HSR) in the murine infection model." | ( In vivo efficacy & resistance prevention of cefiderocol in combination with ceftazidime/avibactam, ampicillin/sulbactam or meropenem using human-simulated regimens versus Acinetobacter baumannii. Echols, R; Gill, CM; Longshaw, C; Nicolau, DP; Santini, D; Takemura, M; Yamano, Y, 2023) | 1.34 |
The relative bioavailability of two injectable formulations of ampicillin trihydrate (PolyflexR, a water-based suspension, and Ampi-kel 10R) was examined in calves, sheep and swine. The use of prodrugs commands the need for further investigation.
| Excerpt | Reference | Relevance |
|---|---|---|
| " Intestinal absorption of bacampicillin was found to be faster and more complete than that of ampicillin, yielding an increase in bioavailability of 30% to 40% as measured by the area under serum levels curve, the urinary excretion and absorption rate constants." | ( Antibacterial activity and pharmacokinetics of bacampicillin and ampicillin. Klastersky, J; Rozencweig, M; Staquet, M, 1976) | 0.8 |
| " The results obtained showed that talampicillin hydrochloride was well absorbed from the gastro-intestinal tract." | ( [Talampicillin hydrochloride: Comparison with amoxicillin and ampicillin in the antibacterial activity and pharmacokinetics (author's transl)]. Komiya, M; Naito, S; Ohtani, K; Shimizu, C; Tachibana, A; Yano, K, 1978) | 1.09 |
| " The bioavailability and urine concentration were also greater." | ( Ampicillin and pivampicillin in the treatment of urinary tract infection in children. Eng, J; Meberg, A; Moe, OJ, 1977) | 1.7 |
| "The influence of various test meals and fluid volume on the relative bioavailability of ampicillin and amoxicillin was studied in healthy human subjects." | ( Bioavailability of ampicillin and amoxicillin in fasted and nonfasted subjects. Craig, WA; Huang, H; Koch, PA; Madsen, PO; Welling, PG, 1977) | 0.81 |
| "7 microgram/ml-h after ampicillin, reflecting the superior bioavailability of the ester form." | ( Oral absorption of pivampicillin and ampicillin in young children: cross-over study using equimolar doses of a suspension. Pedersen-Bjergaard, L; Petersen, KE, ) | 0.76 |
| " It is well absorbed from the gastro-intestinal tract resulting in a greater bioavailiability of ampicillin than can be achieved with equivalent doses of ampicillin itself." | ( Bioavailability and metabolism of talampicillin. Jones, KH; Langley, PF; Lees, LJ, 1978) | 0.75 |
| " It is concluded that our knowledge of the intestinal and especially, the mucosal metabolism of steroids is scanty and further studies are needed to clarify the role of the intestine and enterohepatic circulation in determining the bioavailability of natural and synthetic steroids." | ( Steroid absorption and enterohepatic recycling. Adlercreutz, H; Fotsis, T; Järvenpää, P; Martin, F, 1979) | 0.26 |
| " Knowlege of bioavailability of natural and synthetic hormones in terms of their metabolism in the intestine and enterohepatic circulation is scanty." | ( Steroid absorption and enterohepatic recycling. Adlercreutz, H; Fotsis, T; Järvenpää, P; Martin, F, 1979) | 0.26 |
| "Magnapen is a combination of two well-proven semi-snythetic penicillins which together offer the theoretical advantages of a broad spectrum of activity, good bioavailability and a low incidence of side-effects." | ( Magnapen treatment of infections in the elderly. Middleton, RS; Sinha, HK, 1979) | 0.26 |
| " These findings suggest that 3g amoxycillin plus 1g probenecid provide better bioavailability than 3g amoxycillin alone." | ( Clinical pharmacological studies of amoxycillin: effect of probenecid. Barbhaiya, R; Thin, RN; Turner, P; Wadsworth, J, 1979) | 0.26 |
| " It was found that ampicillin administered intramuscularly to such patients at early postoperative periods was well absorbed not only to the blood but also to the lymph, reaching in parallel its maximum levels in an hour." | ( [Ampicillin pharmacokinetics in the lymph and blood in acute inflammatory diseases of the abdominal cavity organs]. Iarema, IV; Makarenkov, IS; Marshak, AM; Panchenkov, RT; Urtaev, BM, 1979) | 1.5 |
| " The bioavailability of amoxicillin was twice that of ampicillin." | ( Comparative pharmacokinetics of amoxicillin and ampicillin in infants and children. Clahsen, J; Ginsburg, CM; McCracken, GH; Thomas, ML, 1979) | 0.76 |
| " The bioavailability of the esters bacampicillin (86 +/- 11%) and pivampicillin (92 +/- 18%) was significantly greater than that of ampicillin (62 +/- 17%); however, the difference between the esters was not statistically significant." | ( Pharmacokinetics of ampicillin and its prodrugs bacampicillin and pivampicillin in man. Boréus, LO; Ehrnebo, M; Nilsson, SO, 1979) | 0.85 |
| " Ampicillin seemed to be poorly absorbed from the gastrointestinal tract of fowls." | ( Effects of probenecid on blood levels and tissue distribution of ampicillin in fowls and turkeys. Fridman, J; Meshorer, A; Neumann, J; Singer, N; Ziv, E; Ziv, G, ) | 1.28 |
| " A bioavailability study with five brands of ampicillin revealed variations in the serum concentration at 3 hr." | ( Determination and bioavailability of ampicillin. Ahmad, K; Islam, A; Sattar, A, 1977) | 0.79 |
| " Furthermore, bacampicillin had a higher absorption rate than all the other drugs, although there were statistically significant differences only versus ampicillin." | ( Pharmacokinetics of bacampicillin compared with those of ampicillin, pivampicillin, and amoxycillin. Bergan, T; Magni, L; Sjövall, J, 1978) | 0.91 |
| " and oral administration absorption rate of Bacampicillin which is hydrolysed rapidly to Ampicillin in the body was determined as 95%." | ( [Clinical pharmacology of Bacampicillin in comparison to Ampicillin (author's transl)]. Klaus, M; Malerczyk, V; Simon, C, 1978) | 0.81 |
| " Bioavailability was 87% for bacampicillin, compared to 71% for ampicillin." | ( Pharmacokinetic comparison of oral bacampicillin and parenteral ampicillin. Bergan, T, 1978) | 0.81 |
| " The objective of this study was to compare the bioavailability of bacampicillin, a new prodrug of ampicillin which is nearly completely absorbed, to that of high doses of oral ampicillin." | ( Comparative clinical pharmacology of bacampicillin and high oral doses of ampicillin. Magni, L; Sjövall, J; Syvälahti, E, 1978) | 0.76 |
| " The rate of absorption and serum concentrations after giving ampicillin and pivampicillin depend on the type of diet." | ( [Ampicillin concentrations in serum and bile after oral administration of ampicillin and pivampicillin]. Ansorg, R; Burkhardt, K; Peitsch, W, 1975) | 1.4 |
| "The rates at which ampicillin, amoxycillin, metampicillin, hetacillin, and pivampicillin are absorbed from the bovine udder were compared, with the absorption rate of (14C)urea as reference." | ( Absorption of ampicillin derivatives from the bovine udder. Ziv, G, 1976) | 0.94 |
| "The bioavailability of single lots of 250-mg ampicillin capsules, available from 17 distributors and/or manufactures, was determined." | ( Bioavailability of 17 ampicillin products. Melikian, AP; Meyer, MC; Slywka, GW; Whyatt, PL, 1976) | 0.83 |
| " The drug is well absorbed in children with gastroenteritis due to a variety of causes and is distributed, excreted and metabolized in a manner similar to that seen in normal adult volunteers." | ( Pharmacokinetics and efficacy of trimethoprim-sulfamethoxazole in the treatment of gastroenteritis in children. Marks, MI, 1975) | 0.25 |
| "Ampicillin pharmacokinetics was studied in 9 cirrhotic patients and in 8 healthy subjects to assess liver disease-related differences in distribution, elimination, and bioavailability of ampicillin." | ( Pharmacokinetics of ampicillin in cirrhosis. Jusko, WJ; Lewis, GP, 1975) | 2.02 |
| " However, absorption during labour, as reflected by maternal blood levels at delivery and cord blood levels, suggests that amoxycillin is poorly absorbed and may not reach adequate therapeutic levels in the fetus." | ( Gastro-intestinal absorption and transplacental transfer of amoxycillin during labour and the influence of metoclopramide. Buckingham, M; Elstein, M; Miller, JF; Welply, G, 1975) | 0.25 |
| "Bacampicillin (proposed international nonproprietary name), 1'-ethoxycarbonyloxyethyl 6-(d-alpha-aminophenylacetamido)penicillanate, is a new orally well-absorbed penicillin, highly active in vivo due to rapid transformation into ampicillin." | ( Bacampicillin: a new orally well-absorbed derivative of ampicillin. Bodin, NO; Ekström, B; Forsgren, U; Jalar, LP; Magni, L; Ramsay, CH; Sjöberg, B, 1975) | 1.5 |
| " The (absolute) bioavailability of pivampicillin administered orally was 30." | ( Bioavailability of oral penicillins in the horse: a comparison of pivampicillin and amoxicillin. Ensink, JM; Klarenbeek, A; Klein, WR; Mevius, DJ; Vulto, AG, 1992) | 0.79 |
| " administration of ampicillin sodium (20 mg/kg), ampicillin concentrations were systematically higher after a 3-day period of water deprivation than during the control period but the muscular absorption rate was not modified." | ( Effect of water deprivation on absorption (oral, intramuscular) and disposition of ampicillin in sheep. Oukessou, M; Toutain, PL, 1992) | 0.84 |
| "The toxicity and the bioavailability of new ampicillin derivatives with glyoxylic acid benzhydrazones as site chain depend on the hydrophobic properties of the site chain." | ( [Relationship between chemical structure and toxicologic-pharmacokinetic properties of new ampicillin derivatives]. Eckardt, K; Hanschke, KG; Heinisch, L; Horn, U; Möllmann, U; Stengel, K; Willitzer, H, 1992) | 0.77 |
| "Intestinal absorption rate constants of amoxicillin, ampicillin, epicillin, cyclacillin and azidocillin, by means of a static in situ intestinal perfusion method has been estimated." | ( Intestinal absorption kinetics of a series of aminopenicillins and azidocillin. A comparative study in the rat. Margarit, F; Moreno-Dalmau, J; Obach, R; Peraire, C; Plá-Delfina, JM, 1991) | 0.53 |
| " These changes in mefloquine disposition after antibiotic treatment may be due both to an increase in fractional bioavailability and a reduction in the enterohepatic recycling of mefloquine." | ( Effect of ampicillin on mefloquine pharmacokinetics in Thai males. Back, DJ; Bunnag, D; Karbwang, J; Na Bangchang, K, 1991) | 0.68 |
| "Influence of the injection site on bioavailability in dogs was investigated for injections with ampicillin anhydrate or amoxycillin trihydrate suspensions." | ( The influence of the injection site on the bioavailability of ampicillin and amoxycillin in beagles. Broeze, J; Hartman, EG; ten Voorde, G; van Gogh, H, 1990) | 0.74 |
| " Taking this into account the same increase of the bioavailability of AP was obtained in the presence of DS as after application of BAP using the in vitro absorption model system." | ( Ion pair approach of ampicillin using in vitro methods. Dittrich, T; Neubert, R, 1990) | 0.6 |
| "Oral bioavailability of ampicillin when bound to sulbactam (sultamicillin) compared with ampicillin alone and that of amoxycillin with a ligand of clavulanic acid versus amoxycillin alone were assessed in 16 healthy subjects using an open label, multiple crossover study." | ( Oral bioavailability of ampicillin and amoxycillin alone and bound in fixed proportions to sulbactam and clavulanic acid. Costermans, J; Desager, JP; Harvengt, C; Van Nieuwenhuyze, Y, ) | 0.75 |
| " Hypoacidity as such does not reduce the bioavailability of amoxycillin or bacampicillin." | ( No effect of omeprazole-induced hypoacidity on the bioavailability of amoxycillin or bacampicillin. Höglund, P; Paulsen, O; Walder, M, 1989) | 0.73 |
| " We conclude that until bioavailability studies are performed these three antibiotics should not be coadministered with nicardipine HCl." | ( The compatibility of nicardipine hydrochloride injection with various ICU medications during simulated Y-site injection. Alicea, M; Colucci, RD; Greenstein, R; Halpern, NA, 1989) | 0.28 |
| " However, these absorptions were improved enormously by the addition of surface-active agents, that is, an excellent prolonged absorption and high bioavailability were obtained." | ( Studies on sustained-release suppositories. I. Effect of alginic acid addition on rectal absorption of bacampicillin in rabbits. Fujiwara, H; Kawashima, S; Nishiura, N; Noguchi, T, 1989) | 0.49 |
| "Rectal absorption of bacampicillin hydrochloride (BAPC) was found to show the best bioavailability with Witepsol H-15 as suppository base among various Witepsol bases." | ( Studies on sustained-release suppositories. II. Evaluation of polymer electrolyte containing acidic groups for prolonged rectal absorption of bacampicillin in rabbits. Fujiwara, H; Kawashima, S; Noguchi, T; Sugimura, M, 1989) | 0.78 |
| " Sulbactam is poorly absorbed after oral administration and sulbactam/ampicillin is therefore administered parenterally, although another linked sulbactam-ampicillin compound, sultamicillin, has been developed which is well absorbed after oral administration." | ( Sulbactam/ampicillin. A review of its antibacterial activity, pharmacokinetic properties, and therapeutic use. Brogden, RN; Campoli-Richards, DM, 1987) | 0.91 |
| " It is suggested that, if minimal impairment of bioavailability by ingesta is desired, then the penicillins commonly administered by mouth (amoxycillin, ampicillin, penicillin V, phenethicillin, cloxacillin) should be given to dogs that are fasting." | ( Effect of ingesta on systemic availability of penicillins administered orally in dogs. Egerton, JR; Emslie, DR; Martin, IC; Watson, AD, 1986) | 0.47 |
| " The bioavailability after intramuscular injection of the sodium salts was especially low for ampicillin (26 per cent, as against 57 per cent for amoxycillin)." | ( Comparative study of ampicillin and amoxycillin after intravenous, intramuscular and oral administration in homing pigeons (Columba livia). Buitelaar, MN; Dorrestein, GM; Rinzema, JD; Van Gogh, H, 1987) | 0.81 |
| " Test results showed that the addition of sulbactam significantly increases the bioavailability of oral ampicillin when the 2 drugs are administered in the form of the prodrug sultamicillin." | ( Comparative pharmacokinetics of sulbactam/ampicillin and clavulanic acid/amoxycillin in human volunteers. Bruckner, G; Hampel, B; Koeppe, P; Lode, H, 1988) | 0.75 |
| " We assessed the effect of simultaneous oral administration of NAC on the bioavailability of two antibiotics in ten healthy volunteers." | ( No effect of oral N-acetylcysteine on the bioavailability of erythromycin and bacampicillin. Borgström, L; Kågedal, B; Paulsen, O; Walder, M, 1988) | 0.5 |
| "16 M decanoate considerably increased ampicillin bioavailability, to 79 +/- 30%, whereas the absorption rate was not significantly affected." | ( Rectal absorption enhancement of rate-controlled delivered ampicillin sodium by sodium decanoate in conscious rats. Breimer, DD; De Boer, AG; Van Hoogdalem, EJ, 1988) | 0.79 |
| "The influence of time and different ethnic diets on relative bioavailability and pharmacokinetics of orally administered ampicillin was studied in healthy Pakistani subjects." | ( Influence of ethnic diets on ampicillin bioavailability and pharmacokinetics in healthy Pakistani subjects. Beg, AE; Hamid, S, ) | 0.63 |
| "Using the microbiological assay method, the bioavailability of ampicillin in healthy human volunteers has been examined." | ( Bioequivalence studies of five brands of ampicillin trihydrate capsules. Beg, AE; Hamid, S, 1987) | 0.78 |
| " It seems that success in sustained release of a drug depended on the magnitude of the gastric-emptying and intestinal-transit rate constant (kgi) of microcapsules, in the case of a drug with a small absorption rate constant (ka) as observed with ampicillin." | ( In vivo evaluation of ethyl cellulose microcapsules containing ampicillin using rabbits, beagle dogs and humans. Goto, S; Kawata, M; Uchida, T, 1986) | 0.69 |
| " The systematic bioavailability of ampicillin-trihydrate rose with the use of A-149, and dropped with the use of vitamycin A, and to a lower extent--with the use of flavophospholipol." | ( [Effect of feed antibiotics on ampicillin pharmacokinetics in chickens]. Mutafchieva, R; Pashov, D, 1986) | 0.83 |
| " The objective of the study was to compare the in vitro release and bioavailability of bacampicillin hydrochloride from microcapsules coated with two principally different polymers: a water-insoluble polymer, ethylcellulose, and an acid-soluble polymer, Eudragit E 100." | ( In vitro-in vivo evaluation of bacampicillin hydrochloride from microcapsules of water-insoluble and an acid-soluble polymer. Nyqvist, H; Sjöqvist, R; Sjövall, J; Westerlund, D, ) | 0.63 |
| " Consequently, differences in the relative bioavailability were based on urinary recoveries assuming constant non-renal clearance." | ( Oral cyclacillin interacts with the absorption of oral ampicillin, amoxycillin, and bacampicillin. Alván, G; Sjövall, J; Westerlund, D, 1985) | 0.52 |
| "Ampicillin bioavailability was examined using the urinary excretion method, in healthy subjects and patients with: viral hepatitis, primary hepatocellular carcinoma and hepatosplenic schistosomiasis." | ( Investigations on the influence of liver diseases on ampicillin body levels in man. Ali, HM; Hassan, IE; Homeida, MM, 1985) | 1.96 |
| "Ampicillin bioavailability was examined in seven healthy adult male volunteers after oral coadministration with chloroquine using the urinary excretion method." | ( Reduced ampicillin bioavailability following oral coadministration with chloroquine. Ali, HM, 1985) | 2.15 |
| " The bioavailability study was carried out in nine healthy volunteers given one capsule (250 mg) of ampicillin in a completely randomized cross-over design." | ( Comparative bioavailability studies on some brands of ampicillin capsules. Akanni, AO; Ogunbona, FA, 1985) | 0.73 |
| " Since the bioavailability of oral ampicillin is known to be affected by food and fluid volume, a study to evaluate the influence of a lactobacillus product on ampicillin bioavailability was performed." | ( Effect of a lactobacillus preparation on the absorption of oral ampicillin. Gotz, VP; Yost, RL, 1985) | 0.78 |
| "The relative bioavailability of three commercial ampicillin products was examined in 12 human subjects using a crossover experimental design." | ( Relative bioavailability of commercial ampicillin formulations in man. Endrenyi, L; Mayersohn, M, 1973) | 0.78 |
| " Product bioavailability was not related to the in vitro dissolution time of the capsules." | ( Comparative bioavailability of three brands of ampicillin. Caron, M; Davies, RO; MacLeod, C; Rabin, H; Ruedy, J; Zarowny, D, 1972) | 0.51 |
| "The present study was designed to investigate the effect of food and of a raised intragastric pH on the bioavailability of two prodrug beta-lactam, antibiotics, namely bacampicillin and cefuroxime axetil." | ( Influence of food and reduced gastric acidity on the bioavailability of bacampicillin and cefuroxime axetil. Moncrieff, J; Schoeman, HS; Sommers, DK; van Wyk, M, 1984) | 0.69 |
| " There is no change in the rate of absorption of the release sulphapyridine." | ( Azo reduction of sulphasalazine in healthy volunteers. Day, J; Houston, JB; Walker, J, 1982) | 0.26 |
| " First-pass hydrolysis of this prodrug liberates equimolar proportions of sulbactam in plasma, saliva and urine is described and was used to determine the absolute bioavailability of sulbactam and ampicillin from sultamicillin in six normal male volunteers who each received a single 750 mg oral dose of sultamicillin or an iv dose of the equivalent amounts of ampicillin (441 mg) and sulbactam (294 mg)." | ( Pharmacokinetics and bioavailability of sultamicillin estimated by high performance liquid chromatography. Bradbrook, ID; Cox, DA; Lees, LJ; Morrison, PJ; ROgers, HJ; Spector, RG, 1983) | 0.45 |
| "5 times greater total bioavailability for ampicillin and sulbactam than when each was used individually." | ( Pharmacokinetics of sultamicillin in mice, rats, and dogs. English, AR; Girard, D; Haskell, SL, 1984) | 0.53 |
| " There were no significant differences between these three treatments in respect of the serum and bronchial secretion concentrations at the time of bronchoscopy, nor were there any significant differences in the peak serum level or total bioavailability of each regimen." | ( Penetration of ampicillin ('Pondocillin') and amoxycillin ('Imacillin') into bronchial secretions. Hagstad, H, 1984) | 0.62 |
| " This was verified by comparing the predicted plasma response values with the values obtained in a bioavailability study in healthy volunteers." | ( Linear systems analysis and moment analysis in the evaluation of bacampicillin bioavailability from microcapsule suspensions. Ellström, K; Nicklasson, M; Sjöqvist, R; Sjövall, J, 1984) | 0.5 |
| " The relative bioavailability of KS-R1, calculated on the basis of AUC and urinary recovery after intramuscular administration of ABPC sodium, was 23." | ( [Absorption and excretion of an ampicillin suppository (KS-R1) in dogs]. Kakeya, N; Kitao, K; Nishimura, K; Nozaki, Y; Yoshimi, A, 1983) | 0.55 |
| " The relative bioavailability of KS-R1, calculated on the basis of urinary recovery after intravenous administration of ABPC, was about 40%." | ( [Experimental study of an ampicillin suppository (KS-R1) in adults and children]. Fujimoto, T; Ishimoto, K; Koga, T; Kuda, N; Motohiro, T; Nishiyama, T; Sakata, Y; Shimada, Y; Tanaka, K; Tomita, N, 1983) | 0.57 |
| " The bioavailability as measured by urinary recovery of cefuroxime was 40 to 50% if the drug was taken after food and 30% if the drug was taken after overnight fasting." | ( Pharmacology of Cefuroxime as the 1-acetoxyethyl ester in volunteers. Ayrton, J; Harding, SM; Williams, PE, 1984) | 0.27 |
| "The relative bioavailability of microencapsulated bacampicillin hydrochloride in suspension was correlated with the in vitro dissolution half-lives of the microcapsules." | ( Correlation between the bioavailability of microencapsulated bacampicillin hydrochloride in suspension and in vitro microcapsule dissolution. Huitfeldt, B; Nyqvist, H; Sjöqvist, R; Sjövall, J, 1984) | 0.76 |
| "The relative bioavailability of sarpicillin (the methoxymethyl ester of hetacillin) from three different oral dosage forms was compared in humans employing a three-way crossover study design." | ( Evaluation of the bioavailability of sarpicillin, the methoxymethyl ester of hetacillin, in humans. Hottendorf, GH; Martin, A; Newburger, J; Pearlman, RS; Schneider, LW; Smyth, RD; Stavchansky, S; Van Harken, DR, 1984) | 0.27 |
| " The bioavailability of propylthiouracil (about 80%) was unchanged by the surgical procedure but the fraction of ampicillin (given as pivampicillin) absorbed decreased from a preoperative value of 109 +/- 44% to 44 +/- 30% 12 months after the bypass operation." | ( Ampicillin and propylthiouracil pharmacokinetics in intestinal bypass patients followed up to a year after operation. Kampmann, JP; Klein, H; Lumholtz, B; Mølholm Hansen, JE, ) | 1.78 |
| " Pharmacokinetics were studied in 8 volunteers (CAE versus ampicillin), relative bioavailability and tolerance were studied in 100 volunteers (CAE versus pivmecillinam and CAE versus pivampicillin), and tolerance alone was studied in 50 volunteers (CAE versus ampicillin)." | ( Pharmacokinetics and tolerance of cefuroxime axetil in volunteers during repeated dosing. Harding, SM; Sommers, DK; Van Wyk, M; Williams, PE, 1984) | 0.51 |
| "The relative bioavailability of bacampicillin hydrochloride, a pro-drug of ampicillin, was compared after rectal and oral administration." | ( Rectal bioavailability of bacampicillin hydrochloride in man as determined by reversed-phase liquid chromatography. Alván, G; Magni, L; Nord, CE; Sjövall, J; Sörstad, J; Westerlund, D, 1984) | 0.84 |
| " After a single oral dose of 100 mg atenolol combined with 1 gm ampicillin, the bioavailability of atenolol was reduced to 36 +/- 5% compared to 60 +/- 8% after monotherapy." | ( Atenolol interaction with aspirin, allopurinol, and ampicillin. Axthelm, T; Kirch, W; Köhler, H; Mutschler, E; Schäfer-Korting, M, 1983) | 0.76 |
| " During fever, induced with Escherichia coli endotoxin, the rate of absorption of ampicillin from shivering muscles was faster, resulting in significantly higher serum concentrations of the antibiotic than in control non-febrile goats." | ( Factors affecting the absorption of ampicillin administered intramuscularly in dwarf goats. Groothuis, DG; van Duin, CT; van Miert, AS; Werdler, ME, 1980) | 0.76 |
| " Bioavailability and bioequivalence are discussed in terms of the zero and first moments." | ( Moment analysis for the separation of mean in vivo disintegration, dissolution, absorption, and disposition time of ampicillin products. Nakagawa, T; Tanigawara, Y; Uno, T; Yamaoka, K, 1982) | 0.47 |
| " The bioavailability of bacampicillin was two-to threefold greater than that of ampicillin." | ( Comparative pharmacokinetics of bacampicillin and ampicillin suspensions in infants and children. Clahsen, J; Ginsburg, CM; McCracken, GH; Zweighaft, T, ) | 0.71 |
| " It differs from ampicillin in having an ethoxycarbonyloxyethyl group attached to the carboxyl group in C3 of the penicillin nucleus, thus forming an ester with higher bioavailability than ampicillin." | ( Clinical pharmacokinetic evaluation of bacampicillin. Braga, PC; Ceccarelli, G; Fraschini, F; Scaglione, F; Scarpazza, G, 1981) | 0.87 |
| "A 200-mg amount of bacampicillin showed a significantly higher relative extent of bioavailability than did a 250-mg amount of talampicillin, possibly due to their different stability in the digestive juices." | ( Bioavailability of bacampicillin and talampicillin, two oral prodrugs of ampicillin. Magni, L; Sjövall, J; Vinnars, E, 1981) | 0.89 |
| " A two compartment-open model was used to characterise the plasma concentration-time data for the intravenous study, and a one compartment-open model incorporating an absorption lag time and a first-order absorption rate constant for the oral data." | ( Absorption and disposition of ampicillin in the elderly. Johnson, JM; Learoyd, B; Triggs, EJ, 1980) | 0.55 |
| "For the evaluation of the bioavailability of drugs administered through a minimal jejunostomy catheter (MJC) postoperatively, ampicillin and metronidazol were administered via this route." | ( [The bioavailability of drugs administered via a minimal jejunostomy catheter. A clinico-experimental study]. Alarcó, A; Bordallo, AJ; Evora, C; González Hermoso, F; Llabrés, M; Meneses, MM, ) | 0.34 |
| " The bioavailability of ampicillin from two intramuscular products, which had been found to be different in calves, were compared in a two-way crossover design." | ( Rabbit model for estimating relative bioavailability, residues and tissue tolerance of intramuscular products: comparison of two ampicillin products. Boink, AB; Olling, M; Rauws, AG; van Twillert, K; Wester, P, 1995) | 0.8 |
| " When bacampicillin and pivampicillin (two ampicillin prodrugs) were administered to horses, high oral bioavailability was obtained, and the use of prodrugs commands the need for further investigation." | ( Ampicillin and its congener prodrugs in the horse. McKellar, QA; Sarasola, P, ) | 1.99 |
| "5 mg/kg of body weight to ponies and horses, and was highly bioavailable (F = 41." | ( Pharmacokinetics of bacampicillin in equids. McKellar, QA; Sarasola, P, 1995) | 0.6 |
| " On the other hand, assessment of bioavailability in human subjects depicted highly significant increase in both the rate and extent of absorption of the drug." | ( Improvement of some pharmaceutical properties of drugs by cyclodextrin complexation. Part 6: Ampicillin. Ammar, HO; el-Nahhas, SA; Ghorab, MM, 1996) | 0.51 |
| "Absolute oral bioavailability was 31, 39, 23, and 2% for pivampicillin, bacampicillin, talampicillin, and ampicillin sodium, respectively." | ( Oral bioavailability and in vitro stability of pivampicillin, bacampicillin, talampicillin, and ampicillin in horses. Ensink, JM; Fluitman, MA; Tukker, JJ; van Miert, AS; Vulto, AG; Winkel, MB, 1996) | 0.79 |
| " Ampicillin, which binds to feedstuffs to a lesser extent, has a lower bioavailability than pivampicillin." | ( Bioavailability of pivampicillin and ampicillin trihydrate administered as an oral paste in horses. Ensink, JM; Moi, A; Tukker, JJ; Vulto, AG, 1996) | 1.52 |
| " The bioavailability after intramuscular injection was high and similar for both drugs (98." | ( Some pharmacokinetic parameters of ampicillin/sulbactam combination after intravenous and intramuscular administration to goats. Carceles, CM; Escudero, E; Espuny, A; Vicente, MS, 1996) | 0.57 |
| "The study examined the effect of Khat chewing on ampicillin and amoxycillin bioavailability following the administration of a 500 mg single dose of each antibiotic at different times relative to Khat chewing." | ( Effect of Khat chewing on the bioavailability of ampicillin and amoxycillin. Ali, AA; Ali, HM; Attef, OA, 1997) | 0.81 |
| " The overestimated plasma profile of propranolol suggests that the low bioavailability of propranolol is a result of first-pass metabolism by the intestine wall and the liver, because the calculated absolute absorption is almost perfect." | ( Prediction of the plasma concentration profiles of orally administered drugs in rats on the basis of gastrointestinal transit kinetics and absorbability. Haruta, S; Higaki, K; Kimura, T; Kurosaki, Y; Sawamoto, T, 1997) | 0.3 |
| " However, the extent of bioavailability was not changed in theophylline and cephalexin." | ( Absorption behavior of orally administered drugs in rats treated with propantheline. Haruta, S; Higaki, K; Iwasaki, N; Kimura, T; Ogawara, K, 1998) | 0.3 |
| " The bioavailability after intramuscular injection was high and similar in both drugs (72." | ( Pharmacokinetics of an ampicillin-sulbactam combination after intravenous and intramuscular administration to sheep. Cárceles, CM; Escudero, E; Espuny, A; Vicente, S, 1999) | 0.61 |
| "To examine the validity of extrapolating parenteral product bioequivalence determinations across target animal species, the relative bioavailability of two injectable formulations of ampicillin trihydrate (PolyflexR, a water-based suspension, and Ampi-kel 10R, an oil-based suspension) was examined in calves, sheep and swine." | ( Feasibility of interspecies extrapolation in determining the bioequivalence of animal products intended for intramuscular administration. Cullison, R; Jackson, JD; Martinez, MN; Pedersoli, WM; Ravis, WR, 2001) | 0.5 |
| " The bioavailability after intramuscular injection was high and similar in both drugs (73." | ( Pharmacokinetics of an ampicillin/sulbactam (2:1) combination in rabbits. Cárceles, CM; Escudero, E; Serrano, JM; Vicente, MS, 2002) | 0.63 |
| "The in vivo bioavailability and in vitro drug-release studies of ampicillin trihydrate in different oily and aqueous suspensions have been investigated." | ( Effects of oils and pharmaceutical excipients on the bioavailability of ampicillin orally administered, different oily and aqueous suspensions in rabbit. Alhamami, OM, 2003) | 0.79 |
| " This ester compound of ampicillin showed zero violations of the 'Rule of 5', which indicates good bioavailability and good bioactivity." | ( Synthesis, structural analysis and antibacterial activity of a butyl ester derivative of ampicillin. Bartzatt, R; Malesa, C, 2003) | 0.85 |
| " Favorable values for parameters such as TPSA, log P, log BB, and zero violations of the 'Rule of 5' suggest good bioavailability and good bioactivity." | ( Synthesis, structural analysis and antibacterial activity of a butyl ester derivative of ampicillin. Bartzatt, R; Malesa, C, 2003) | 0.54 |
| " The pharmaceutical quality of the products and a sample from a batch produced by a local manufacturer was evaluated and five of the capsule samples were employed in an in vivo bioavailability study." | ( Quality and bioavailability of ampicillin capsules dispensed in a Nigerian semi-urban community. Lamikanra, A; Okeke, IN, ) | 0.42 |
| " The aim of the present studies, performed in two different groups of volunteers, was to compare the bioavailability of 750 mg sultamicillin tablets (Duobaktam 750 mg tablets, study 1) and sultamicillin 250 mg/5mL suspensions (Duobaktam 250 mg/5mL, study 2)." | ( Effect of the formulation on the bioequivalence of sultamicillin: tablets and suspension. Alpan, RS; Erenmemisoglu, A; Koytchev, R; Kunter, U; Ozalp, Y, 2004) | 0.32 |
| "To investigate the disposition kinetics of ampicillin and sulbactam after IV and IM administration of an ampicillin-sulbactam (2:1) preparation and determine the bioavailability of the combined preparation after IM administration in turkeys." | ( Pharmacokinetics of a combination preparation of ampicillin and sulbactam in turkeys. Cárceles, CM; Escudero, E; Espuny, A; Fernández-Varón, E; Marín, P, 2004) | 0.84 |
| " Bioavailability after IM injection was 58." | ( Pharmacokinetics of a combination preparation of ampicillin and sulbactam in turkeys. Cárceles, CM; Escudero, E; Espuny, A; Fernández-Varón, E; Marín, P, 2004) | 0.58 |
| "Pivampicillin (PIVA), an acyloxymethylester of ampicillin, is thought to enhance the oral bioavailability of ampicillin because of its greater lipophilicity compared to that of ampicillin." | ( Accumulation and oriented transport of ampicillin in Caco-2 cells from its pivaloyloxymethylester prodrug, pivampicillin. Chanteux, H; Mingeot-Leclercq, MP; Tulkens, PM; Van Bambeke, F, 2005) | 1.22 |
| "The utilization of the membrane transport protein PEPT1 as a drug delivery system is a promising strategy to enhance the oral bioavailability of drugs." | ( Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1. Biegel, A; Brandsch, M; Gebauer, S; Hartrodt, B; Neubert, K; Thondorf, I, 2005) | 0.33 |
| " The corresponding mean absolute oral bioavailability figures were 36, 32, 39, 42 and 32% for ampicillin and 76, 74, 85, 73 and 74% for antipyrine, respectively." | ( Excipient effects on gastrointestinal transit and drug absorption in beagle dogs. Basit, AW; Coffin, MD; Parsons, GE; Peters, EE; Schulze, JD; Staton, JS; Vickers, AW, 2005) | 0.55 |
| " The selectivity of PTC124 for premature termination codons, its well characterized activity profile, oral bioavailability and pharmacological properties indicate that this drug may have broad clinical potential for the treatment of a large group of genetic disorders with limited or no therapeutic options." | ( PTC124 targets genetic disorders caused by nonsense mutations. Almstead, NG; Babiak, J; Barton, ER; Branstrom, AA; Campbell, JA; Chen, G; Colacino, JM; Conn, MM; Corson, D; Feng, H; Friesen, WJ; He, F; Hedrick, J; Hirawat, S; Hwang, S; Jacobson, A; Jones, S; Ju, WD; Karp, G; Kawana, M; Khan, A; Miller, LL; Mollin, A; Moon, YC; Northcutt, VJ; Patel, M; Paushkin, S; Peltz, SW; Ren, H; Risher, N; Spatrick, P; Sweeney, HL; Takasugi, J; Tomizawa, Y; Trifillis, P; Trotta, CR; Turpoff, AA; Weetall, M; Welch, EM; Wilde, RG; Yeh, S; Zhuo, J, 2007) | 0.34 |
| " The present study was performed to investigate the relative bioavailability and to assess the bioequivalence of two different sultamicillin suspensions (Devasid 250 mg/5 ml as test preparation and 375 mg/7." | ( Bioequivalence study of sultamicillin suspensions. Arnold, P; Erenmemişoğlu, A; Hincal, AA; Kanzik, I; Martin, W; Sailer, R; Tamur, U, 2007) | 0.34 |
| "The beta-lactam antibiotic ampicillin has a relatively poor oral bioavailability in animals and man (30-40%), and its widespread agricultural use in livestock may be contributing to the emergence of antibiotic resistance in the environment." | ( Oral absorption of ampicillin: role of paracellular route vs. PepT1 transporter. Arellano, C; Bousquet-Mélou, A; Dupouy, V; Gandia, P; Houin, G; Lafforgue, G; Philibert, C; Vachoux, C; Woodley, J, 2008) | 0.97 |
| "Oral bioavailability (F) is a product of fraction absorbed (Fa), fraction escaping gut-wall elimination (Fg), and fraction escaping hepatic elimination (Fh)." | ( Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV, 2010) | 0.36 |
| " Pivampicillin was absorbed well in non-fasted horses with an oral bioavailability of 36%." | ( Pharmacokinetics in pulmonary epithelial lining fluid and plasma of ampicillin and pivampicillin administered to horses. Baptiste, KE; Friis, C; Winther, L, 2012) | 1.17 |
| " A good correlation was obtained between the theoretical predictions of bioavailability using Lipinski's rule-of-five and experimental verification." | ( Synthesis, biopharmaceutical characterization, antimicrobial and antioxidant activities of 1-(4'-O-β-D-glucopyranosyloxy-2'-hydroxyphenyl)-3-aryl-propane-1,3-diones. Ben Hadda, T; Chohan, Z; Ingle, V; Juneja, H; Parvez, A; Sheikh, J; Youssoufi, M, 2011) | 0.37 |
| "In order to overcome the problems associated with low water solubility, and consequently low bioavailability of active pharmaceutical ingredients (APIs), herein we explore a modular ionic liquid synthetic strategy for improved APIs." | ( Evaluation of solubility and partition properties of ampicillin-based ionic liquids. Alves, F; Araújo, JM; Branco, L; Ferraz, R; Florindo, C; Marrucho, IM; Matos, C; Noronha, JP; Petrovski, Ž; Prudêncio, C; Rebelo, LP, 2013) | 0.64 |
| "These results showed that antibiotic intake might increase the bioavailability of amlodipine by suppressing gut microbial metabolic activities, which could be followed by changes in therapeutic potency." | ( Effects of orally administered antibiotics on the bioavailability of amlodipine: gut microbiota-mediated drug interaction. Kim, DH; Kim, IS; Yoo, DH; Yoo, HH, 2016) | 0.43 |
| " Our findings reveal that an orally bioavailable TLR-7 ligand that stimulates innate antiviral immune pathways in the intestine restores colonization resistance against a highly antibiotic-resistant bacterial pathogen." | ( TLR-7 activation enhances IL-22-mediated colonization resistance against vancomycin-resistant enterococcus. Abt, MC; Artis, D; Becattini, S; Buffie, CG; Carter, RA; Keith, JW; Leiner, I; Osborne, LC; Pamer, EG; Sušac, B, 2016) | 0.43 |
| "Quinine therefore, reduced the bioavailability and the antimicrobial activity of ampicillin-cloxacillin upon co-administration, which may have therapeutic implications." | ( Significant Pharmacokinetic Interactions Between Quinine and Ampicillin-Cloxacillin Combination. Babalola, CP; Ezeasor, C; Falade, OB; Falusi, AG; Kwasi, DA; Olaniyi, AA, 2016) | 0.9 |
| "The pharmaceutical excipient, polyethylene glycol 400 (PEG 400), unexpectedly alters the bioavailability of the BCS class III drug ranitidine in a sex-dependent manner." | ( Excipient-mediated alteration in drug bioavailability in the rat depends on the sex of the animal. Afonso-Pereira, F; Basit, AW; Mai, Y; Murdan, S, 2017) | 0.46 |
| "The bioavailability of metals can be influenced not only by soil properties but also by other species living at polluted sites." | ( The effect of the earthworm Lumbricus rubellus on the bioavailability of cadmium and lead to the springtail Folsomia candida in metal-polluted field soils. Ardestani, MM; Giska, I; van Gestel, CAM, 2019) | 0.51 |
| "The ATP-binding cassette transporter P-glycoprotein (P-gp) is known to limit both brain penetration and oral bioavailability of many chemotherapy drugs." | ( A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Ambudkar, SV; Brimacombe, KR; Chen, L; Gottesman, MM; Guha, R; Hall, MD; Klumpp-Thomas, C; Lee, OW; Lee, TD; Lusvarghi, S; Robey, RW; Shen, M; Tebase, BG, 2019) | 0.51 |
| " An increasing number of studies have revealed that the traditionally regarded "inert" excipients can, however, influence the bioavailability of drugs." | ( Sex-specific and concentration-dependent influence of Cremophor RH 40 on ampicillin absorption via its effect on intestinal membrane transporters in rats. Deng, W; Liu, J; Qin, Y; Shao, H; Yin, H, 2022) | 0.95 |
| " These impacts are a result of alterations in API bioavailability: pH regulates the bioavailability of many ionizable APIs via chemical speciation, whereas DOC interacts with several APIs to inhibit the APIs from traversing the membrane system of organisms." | ( The influence of pH and dissolved organic carbon on the ecotoxicity of ampicillin and clarithromycin. De Schamphelaere, KAC; Demeestere, K; Zhang, Q, 2023) | 1.14 |
Ultrasound reduced the dosage of ampicillin required to impair bacterial viability. The dosing interval for horses may be increased from between six and eight hours to 12 hours when probenecid is administered in conjunction with the ampicisin.
| Excerpt | Relevance | Reference |
|---|---|---|
| " At moderate and high dosage levels, PC 904'S efficacy was comparable to carbenicillin's but much less than gentamicin's." | ( In vitro and in vivo effect of PC 904, a new broad-spectrum penicillin, on ocular strains of Pseudomonas aeruginosa. Dy-Liacco, J; Mintsioulis, G; Ohno, S; Okumoto, M; Smolin, G, 1978) | 0.26 |
| "These recommendations specify appropriate treatment, including dosage of antibiotics for uncomplicated gonococcal infections in adults, infections with penicillinase-producing Neisseria gonorrhoeae, acute salpingitis, acute epididymitis, disseminated gonococcal infections, and gonococcal infections in pediatric patients (including neonatal infections)." | ( Gonorrhea. Center for Disease Control recommended treatment schedules, 1979. , 1979) | 0.26 |
| " calcoaceticus in mice, minocycline was, in general, more active than gentamicin or polymyxin on a dosage basis and significantly more active on a blood-level basis." | ( In vitro and in vivo activities of minocycline and other antibiotics against Acinetobacter (Herellea-Mima). Kuck, NA, 1976) | 0.26 |
| " Erythromycin in a dosage of 40--50 mg/kg/day was significantly more effective than amoxycillin in a dosage of 25--30 mg/kg/day." | ( Effect of erythromycin and amoxycillin on Bordetella pertussis in the nasopharynx. Trollfors, B, 1978) | 0.26 |
| " Despite the fact that pivampicillin was administered in half of the dosage of ampicillin the resulting peak serum concentration was 65% higher and was achieved more rapidly." | ( Ampicillin and pivampicillin in the treatment of urinary tract infection in children. Eng, J; Meberg, A; Moe, OJ, 1977) | 2 |
| "The pharmacological and clinical properties of bacampicillin in three dosage groups were studied in 66 hospitalized patients with unilateral acute peritonsillitis in a comparison with ampicillin." | ( Pharmacological and clinical study of bacampicillin in acute peritonsillitis--a comparison with ampicillin. Flodström, A; Hallander, HO; Sjövall, J, 1977) | 0.78 |
| " Food ingested immediately before dosing reduced serum levels and urinary excretion of both antibiotics to a similar extent." | ( Bioavailability of ampicillin and amoxicillin in fasted and nonfasted subjects. Craig, WA; Huang, H; Koch, PA; Madsen, PO; Welling, PG, 1977) | 0.59 |
| " The daily dosage of penicillin G ranged from 110,000 to 165,000 U/kg (50,000-75,000 U/lb), and the dosage of ampicillin varied from 77 to 110 mg/kg (35-50 mg/lb)." | ( Penicillin G or ampicillin for oral treatment of canine urinary tract infections. Gilmore, CJ; Ling, GV, 1977) | 0.81 |
| " A gene dosage effect was found for strains homozygous for ampA+ ampC+ or ampA1 ampC+." | ( Resistance of Escherichia coli to penicillins: fine-structure mapping and dominance of chromosomal beta-lactamase mutations. Burman, LG; Normark, S, 1977) | 0.26 |
| " Dosing of ampicillin after food has been shown to adversely affect the total bioavailability of ampicillin." | ( Bioavailability and metabolism of talampicillin. Jones, KH; Langley, PF; Lees, LJ, 1978) | 0.92 |
| "A randomized clinical trial in sixty-two adult patients suffering from typhoid fever, proved by blood and marrow culture, showed that amoxycillin in a dosage schedule of 1 g 8-hourly orally for fourteen days was better than chloramphenicol with regard to clinical and temperature response and in respect of carriers and relapse rates." | ( Comparative clinical trial of amoxycillin and chloramphenicol in the treatment of typhoid in adults. Abengowe, CU, 1979) | 0.26 |
| "In a systematic study of dose-response relationship 883 patients with uncomplicated gonorrhoea were given single oral doses of 400, 800 or 1600 mg bacampicillin, with 1 g probenecid." | ( A dose response study with bacampicillin in uncomplicated gonorrhoea. Bengtsson, S; Eriksson, G; Kallings, LO; Sandström, E; Wallin, J; Wallmark, G, 1979) | 0.75 |
| " Patients with acute urinary tract infections given 400 mg bacampicillin and patients with chronic infections given double that dosage showed equally good results." | ( Elimination of bacteria during antibacterial chemotherapy--a neglected parameter of chemotherapy. Helm, EB; Munk, I; Shah, PM; Stille, W, 1979) | 0.5 |
| " Amoxycillin Trihydrate appears to be a safe and effective drug as there were no side effects or toxic manifestation even with the high dosage schedule." | ( Amoxycillin trihydrate (Ibeamox) in the treatment of pyogenic meningitis-a preliminary report. Channa, NM; Farooq, S; Haquani, AH, 1977) | 0.26 |
| " We present a dosage nomogram for making appropriate adjustments to loading dose based on patient weight and maintenance dose based on corrected creatinine clearance." | ( Pharmacokinetics of amoxicillin: Dosage nomogram for patients with impaired renal function. Fillastre, JP; Humbert, G; Leroy, A; Spyker, DA, 1979) | 0.26 |
| " We present a dosage schedule for intravenous amoxicillin in patients with reduced renal function who are undergoing hemodialysis." | ( Kinetics of intravenous amoxicillin in patients on long-term dialysis. Appel, GB; Francke, EL; Neu, HC, 1979) | 0.26 |
| " 10 tablets (possibly even less) are thus the minimal inhibitory dosage for the disease." | ( [Minimal effective dose of bacampicillin in urinary tract infections (author's transl)]. Fröhner, H; Höffler, D, 1979) | 0.55 |
| " But with amoxycillin and the ampicillin esters the absorbed amount (AUC) is a linear function of the dose in the dosage range investigated." | ( Dose dependence in human absorption of aminopenicillins. Sjövall, J, 1979) | 0.55 |
| " The high concentration of ampicillin in middle ear effusions after twelve hours suggests that a twice daily dosage of bacampicillin should be given in acute otitis media." | ( Ampicillin concentrations in middle ear effusions in acute otitis media after administration of bacampicillin. Lahikainen, EA; Virtanen, S, 1979) | 2 |
| "3 micrograms/ml of urethral secretion one and two hours, respectively, after the same dosage as above." | ( Penetration of ampicillin into urethral and cervical secretions after oral administration of bacampicillin. Eriksson, G; Hoffner, S; Kallings, LO; Linse, UB, 1979) | 0.61 |
| " The use of a high daily dosage of 3 g per day was neither a cause of more frequent nor more severe side-effects than the usually smaller posology used in other studies published in the literature." | ( [Current aspects of clinical bronchopulmonary and cardiovascular clinical pharmacology. Talampicillin in acute bronchopulmonary diseases in mine workers]. Bruninx, M; Minette, A, 1979) | 0.48 |
| " Nine of ten patients who were able to take the full amoxicillin regimen were cured; among five patients treated with a lower daily amoxicillin dosage because of gastrointestinal (GI) side effects, only two were cured (P less than ." | ( Treatment of typhoid carriers with amoxicillin. Correlates of successful therapy. Nolan, CM; White, PC, 1978) | 0.26 |
| " Based on the above results, it was concluded that clinical effect of broadcillin 'Banyu' by an intravenous administration is comparable to its intramuscular route and that safety of intravenous usage seems to be verified as long as the above described dosage is followed." | ( [Clinical evaluation of intravenous administration of ampicillin-oxacillin (Broadcillin 'Banyu') in bacterial infections in children (author's transl)]. Fujiwara, T; Haruta, T; Honke, K; Kobayashi, Y; Konishi, I; Maruyama, S; Morikawa, Y; Nakamura, K; Nanba, I; Tomizawa, T; Yamamoto, I, 1978) | 0.51 |
| " The pattern of radiometabolites was very similar in extracts of the urines of radiometabolites was very similar in extracts of the urines of rat, dog and man dosed orally with [phthalidyl-14C]talampicillin." | ( The metabolism of talampicillin in rat, dog and man. Jeffery, DJ; Jones, KH; Langley, PF, 1978) | 0.77 |
| " 1) PC-904 was intravenously administered at the daily dosage of 20 approximately 120 mg/kg to 13 children; urinary tract infection (10 cases), acute pneumonia (1 case), sepsis (1 case) and purulent meningitis (1 case)." | ( [A clinical study of PC-904 in pediatric field (author's transl)]. Aoyama, R; Izumi, Y; Kudo, M; Nagata, K; Sato, S, 1978) | 0.26 |
| " The satisfactory results were also obtained by the treatment of almost the same dosage in the patients with acute bronchitis, bronchopneumonia and measles pneumonia." | ( [Fundamental and clinical studies in pediatrics on PC-904, a penicillin with broad spectrum newly developed in Japan (author's transl)]. Chikaoka, H; Fujii, N; Hirama, Y; Irino, Y; Kojima, S; Nakazawa, S; Narita, A; Niino, K; Oka, S; Sato, H; Tanaka, E, 1978) | 0.26 |
| " The daily dosage varied from 30 to 49 mg/kg in 3 cases and from 50 to 70 mg/kg in 3 cases, and was 227 mg/kg in 1 case." | ( [Clinical study of PC-904 in pediatrics (author's transl)]. Hachimori, K; Minamitani, M, 1978) | 0.26 |
| " The results obtained in this fundamental study led to the suggestion that the proper dosage in bacterial infections would be 50 approximately 100 mg/kg intravenously in 3 approximately 4 divided doses daily." | ( [A clinical study of PC-904 in pediatrics (author's transl)]. Hashimoto, F; Hori, M; Kono, S, 1978) | 0.26 |
| " Daily dosage was 100 approximately 150 mg/kg and intravenous infusions were carried out in 2 or 3 divided doses." | ( [Clinical studies of PC 904 in pediatrics (author's transl)]. Kawamura, M; Maki, T; Takashima, Y; Tauchi, N; Uozumi, K, 1978) | 0.26 |
| " The daily dosage varied from 60 to 223." | ( [Clinical studies of PC-904 in pediatrics (author's transl)]. Ishimoto, K; Motohiro, T; Nakajima, T; Nishiyama, T; Sakata, Y; Tominaga, K; Yamashita, F; Yokochi, K, 1978) | 0.26 |
| " In addition, it was found that predictable blood levels of cephazolin could be obtained in patients with renal failure when dosage was regulated according to a nomogram calculated from the patient's serum half-life based on clearance of creatinine." | ( Cephazolin: a comparison to ampicillin in respiratory and urinary infections with dosage regulation by a nomogram. Benner, EJ; Bush, WG; Kranhold, JF, 1976) | 0.55 |
| " The lethality has in fact decreased during the period of observation, but the prognosis of pneumococcal meningitis has not been decisively improved by high dosage therapy with penicillin or ampicillin." | ( [The effect of modern therapy on the course of purulent meningitides (author's transl)]. Kunst, H, 1976) | 0.45 |
| " These results indicate that it is necessary to monitor gentamicin therapy by laboratory assay to ensure adequate dosage and that peak serum concentrations of 8 mug/ml or more are significantly correlated with successful treatment of pneumonia caused by coliforms and Ps." | ( Pneumonia caused by coliforms and Pseudomonas aeruginosa. Noone, P; Rogers, BT, 1976) | 0.26 |
| " The ratios of ampicillin in prostatic fluid relative to plasma levels were higher after dosing with the hetacillin ester." | ( Pharmacokinetics of ampicillin and methoxymethyl ester of hetacillin in dogs. Kjaer, TB; Madsen, PO; Welling, PG, 1977) | 0.93 |
| " Ampicillin in this dosage was well tolerated except in three children in whom severe urticarial rashes developed and two who had significant diarrhea." | ( Typhoid outbreak in Kingston, Ont: experience with high-dose oral ampicillin. Chadwick, P; Hardy, G; Padfield, CJ; Partington, MW, 1977) | 1.4 |
| " No correlation was observed between the risk of diarrhea and the duration of treatment, total dosage of drug, route of administration, or type of underlying disease." | ( Diarrhea associated with clindamycin and ampicillin therapy: preliminary results of a cooperative study. Gurwith, MJ; Love, K; Rabin, HR, 1977) | 0.52 |
| " The tendency to develop diarrhea was positively correlated with serious illness, abdominal or pelvic sepsis, and total dosage of clindamycin." | ( Gastrointestinal side effects of clindamycin and ampicillin therapy. Bodendorfer, T; Devine, BJ; Fekety, FR; Kawanishi, H; Korff, L; Lusk, RH; Nakauchi, D; Rogers, S; Silva, J; Siskin, SB, 1977) | 0.51 |
| " Dosage and therapeutical results are presented." | ( [Amoxicillin and its excretion into bronchial secretion (author's transl)]. Baum, W; Brömme, W; Patsch, R; Richter, I; Thiemann, HH; Vorwald, U; Weingärtner, L, 1977) | 0.26 |
| " Bacampicillin was given in a dosage regimen of 400 mg or 800 mg three times daily." | ( Lower respiratory tract infections treated with bacampicillin: a dose comparison. Sjövall, J, 1977) | 1.07 |
| "Holstein bull calves received ampicillin sodium by the intravenous, intramuscular and subcutaneous routes and ampicillin trihydrate by the intramuscular route, at a dosage of 5 mg/kg." | ( Serum ampicillin levels in the calf: influence of dosage, route of administration and dosage form. Black, WD, 1976) | 1.03 |
| " Its cure rate has been relative, and because cure rates are not as good as one would wish, an additional increase in dosage has been advised." | ( Treatment of uncomplicated gonorrhea with Polycillin-PRB. Hall, SW; Hartford, TJ; Kleris, GS, 1976) | 0.26 |
| "Thirty subjects, free of any heart, kidney or liver disease, were given the same dosage of amoxycillin--100 mg/kg/24 hr." | ( Pharmacokinetics of amoxycillin according to administration schedule. Aubertin, JM; Lacut, JY; Leng, BM, 1976) | 0.26 |
| " Bacillus subtilis is used as test germ for dosage of ampicillin and Sarcina lutea for the dosage of erythromycin." | ( [Passage into normal salivary, lacrimal and nasal secretions of ampicillin and erythromycin administered intramuscularly]. Melon, J; Reginster, M, 1976) | 0.74 |
| " The drugs were given in routine oral dosage for eight days to two patient groups each consisting of 50 patients." | ( A comparison of dicloxacillin and ampicillin in the antibiotic prophylaxis of total hip replacement. Antila, P; Laurent, LE; Visuri, T, 1976) | 0.53 |
| " In the rat these same dosage levels produced urinary inhibitory activity equivalent to 16 to 140 fold that required for 90 per cent urease inhibition." | ( Benurestat, a urease inhibitor for the therapy of infected ureolysis. Andersen, JA, 1975) | 0.25 |
| "Prophylactic (preventive) antibiotic therapy initiated preoperatively, with antibiotics administered in moderately high dosage for short periods, is recommended on the basis of experimental and prospective, randomized clinical trials for patients who require surgery that is likely to expose tissue planes to contamination." | ( Prophylactic antibiotic therapy in surgery. MacLean, LD, 1975) | 0.25 |
| " Amoxycillin was also significantly more active than ampicillin in the treatment of infection by intraperitoneal dosing as a result of greater bactericidal activity in infected mice together with the production of higher antibiotic blood levels." | ( Comparative effects of amoxycillin and ampicillin in the treatment of experimental mouse infections. Comber, KR; Osborne, CD; Sutherland, R, 1975) | 0.77 |
| " In a second series of 27 orthotopic liver transplantations in tissue-typed littermate dogs and littermate pigs the standard surgical technique and aftercare were changed with regard to four factors: an end-to-end common bile duct anastomosis was made instead of a gallbladder to duodenum anastomosis; the continuous postoperative bacteriostatic antibiotic therapy was changed to a single 2-day course of bactericidal antibiotics; preoperative selective bowel decontamination combined with postoperative protective isolation was introduced; the dosage of azathioprine used for immunosuppression was reduced." | ( Orthotopic liver transplantation: an experimental study on the prevention of infections with Gram-negative organisms. Hendriks, WD; Jerusalem, C; Krom, RA; Popescu, DT; Schalm, SW; Terpstra, JL; Van Der Waay, D, 1975) | 0.25 |
| " If it is used a high dosage is necessary because the bone levels which we investigated were very low." | ( [Gentamicin in orthopedic surgery]. Krämer, J; Maassen, H; Rosin, H, 1975) | 0.25 |
| " On the other hand, reduction in dosage may be called for when there is renal impairment." | ( Pharmacokinetics of ampicillin in cirrhosis. Jusko, WJ; Lewis, GP, 1975) | 0.58 |
| " Controls over a 15-weeks period showed that this dosage did prevent the development of syphilitic orchitis and reactivity to the quantitative FTA-ABS-test." | ( [The effect of pivampicillin and probenecid on experimental syphilis in rabbits]. Petzoldt, D, 1975) | 0.59 |
| " The drugs were given in routine oral dosage for eight days to two patient groups each consisting of 50 patients." | ( A comparison of dicloxacillin and ampicillin in the antibiotic prophylaxis of total hip replacement. Antila, P; Laurent, LE; Visuri, T, 1976) | 0.53 |
| "Talampicillin hydrochloride, the phthalidyl ester of ampicillin, when given in a dosage containing the equivalent of 125 mg of ampicillin four times daily for six days to general practice patients, has proved to be as effective, both clinically and bacteriologically, as 250 mg of ampicillin given four times daily for six days." | ( A comparative study of talampicillin and ampicillin in general practice. Jaffé, G; Murphy, JE; Robinson, OP, 1976) | 1.18 |
| " Animals infected with strain SF-195 received 5 days of no therapy, ampicillin, ampicillin-gentamicin, vancomycin, or daptomycin (all at the dosage regimens described above)." | ( Comparison of daptomycin, vancomycin, and ampicillin-gentamicin for treatment of experimental endocarditis caused by penicillin-resistant enterococci. Bayer, AS; Eliopoulos, GM; Grayson, ML; Ramos, MC, 1992) | 0.78 |
| "Twenty full term neonates with suspected bacterial infection were randomly assigned to a once daily or a twice daily dosage regimen with gentamicin (4 mg/kg/day)." | ( Pharmacokinetics and antibacterial activity of daily gentamicin. Heimann, G; Nies, B; Skopnik, H; Tröster, K; Wallraf, R, 1992) | 0.28 |
| " The ampicillin concentrations observed suggest that the dosing interval for horses may be increased from between six and eight hours to 12 hours when probenecid is administered in conjunction with the ampicillin." | ( Effect of probenecid on disposition kinetics of ampicillin in horses. McKellar, QA; Sarasola, P, 1992) | 1.05 |
| " The daily dosage of Unasyn was 3-12 g/die administered in three to four divided doses, and was determined by the severity of infection, the antibiotic susceptibility of the causative organism(s) and the condition of the patient." | ( [Sulbactam-ampicillin in surgery. Our experience]. Casiraghi, S; Caspani, P; Germiniani, R; Pace, M; Trabucchi, E, 1992) | 0.67 |
| " The therapeutic relevance of the results are discussed for a better definition of dosage regimens for sheep reared in arid environments." | ( Effect of water deprivation on absorption (oral, intramuscular) and disposition of ampicillin in sheep. Oukessou, M; Toutain, PL, 1992) | 0.51 |
| " All antibiotics were given by intravenous bolus injection in a number of dosing regimens." | ( Use of ampicillin-sulbactam for treatment of experimental meningitis caused by a beta-lactamase-producing strain of Escherichia coli K-1. Fournier, MA; Guerra-Romero, L; Kennedy, SL; Täuber, MG; Tureen, JH, 1991) | 0.74 |
| " The dramatic response of our patients to cyclophosphamide, which is known to inhibit cell-mediated cytotoxicity by inhibiting both the recognition and lethal hit stages, together with the rapid regrowth of the epidermis within 4 days to a week in patients who received adequate dosage of the drug, supports the preceding concepts." | ( Efficacy of cyclophosphamide in toxic epidermal necrolysis. Clinical and pathophysiologic aspects. Allen, SG; Heng, MC, 1991) | 0.28 |
| "A total of 124 patients with lower respiratory tract (44) or urinary tract infections (80) were enrolled in an open, multicenter study to evaluate the efficacy and tolerability of sulbactam/ampicillin, administered at the dosage of 3 g/die by intramuscular route." | ( Clinical results of a multicenter study with sulbactam/ampicillin for the treatment of patients with lower respiratory and urinary tract infections. Chiodo, F; De Simone, C; Delia, S; Gargiulo, M; Paoloni, M; Pastore, G; Scalise, G; Sorice, F; Tonietti, G; Zanussi, C, 1991) | 0.72 |
| " There were no significant differences between the two dosage regimens regarding efficacy and safety." | ( Efficacy and safety of amikacin in systemic infections when given as a single daily dose or in two divided doses. Scandinavian Amikacin Once Daily Study Group. Ahrne, H; Eilard, T; Eriksson, I; Lausen, I; Maller, R, 1991) | 0.28 |
| " The unnecessary use of antibiotics was the single most common type of misuse in both groups, but errors in dosing collectively accounted for nearly one-half of antibiotic misuse." | ( Antibiotic misuse in two clinical situations: positive blood culture and administration of aminoglycosides. Casabar, E; Dunagan, WC; Gray, JL; Lawrenz, C; Medoff, G; Smith, MD; Spitznagel, E; Woodward, RS, ) | 0.13 |
| " It was concluded that both drugs could be administered concomitantly without any dosage adjustment of theophylline." | ( Influence of sulbactam plus ampicillin on theophylline clearance. Caputi, M; Cazzola, M; Girbino, G; Guidetti, E; Mattina, R; Santangelo, G, 1991) | 0.58 |
| " The dosage was considered appropriate in 88% of the patients." | ( Use of ampicillin-sulbactam before and after formulary inclusion. Koch, KE; Taylor, MR, 1991) | 0.74 |
| " The oral dosing of P-GHA significantly inhibited the elevation of the urinary ammonia level of rats having the urinary tract infection with Proteus mirabilis." | ( Evaluation of effects of novel urease inhibitor, N-(pivaloyl)glycinohydroxamic acid on the formation of an infection bladder stone using a newly designed urolithiasis model in rats. Kobashi, K; Munakata, K; Satoh, M; Takebe, S; Takeuchi, H; Yoshida, O, 1991) | 0.28 |
| " The treatment was continued for at least 7 days for 24 patients at the dosage of 3 g sulbactam/ampicillin twice daily, for a further 24 patients at the dosage of 6 g piperacillin twice daily and for two patients at the dosage of 8 g piperacillin twice daily." | ( Sulbactam/ampicillin combination in the treatment of acute and chronic lower respiratory infections. Bisetti, A; Grassi, L; Putti, P; Scacciacillani, E, 1991) | 0.9 |
| "Serum levels achieved within 90 minutes of equivalent intraosseous (IO) and IV bolus dosing of ceftriaxone, cefotaxime, and a combination of ampicillin and gentamicin were compared in the weanling pig." | ( Intraosseous administration of antibiotics: same-dose comparison with intravenous administration in the weanling pig. Parks, BR; Pender, ES; Pollack, CV; Woodall, BN, 1991) | 0.48 |
| " Serum levels of ceftriaxone after IO administration paralleled those after IV dosing but remained significantly lower at all time intervals." | ( Intraosseous administration of antibiotics: same-dose comparison with intravenous administration in the weanling pig. Parks, BR; Pender, ES; Pollack, CV; Woodall, BN, 1991) | 0.28 |
| " The mean peak ampicillin and sulbactam serum concentrations following intravenous dosing were 170." | ( Ampicillin and sulbactam pharmacokinetics and pharmacodynamics in continuous ambulatory peritoneal dialysis (CAPD). Blackwell, BG; Craig, WA; Johnson, CA; Leggett, JE; Zimmerman, SW, 1990) | 2.07 |
| " Single oral dosing of 20 mg/kg of either ofloxacin or ciprofloxacin showed that ofloxacin achieves approximately a four-fold higher peak serum or liver concentration than ciprofloxacin, which may contribute to its better efficacy in this infection model." | ( In-vivo evaluation of ofloxacin in Salmonella typhimurium infection in mice. Fu, KP; Hilliard, J; Isaacson, D; McGuire, JL; Rosenthale, ME; Tobia, AJ, 1990) | 0.28 |
| " Blood and sputum samples were collected at timed intervals following dosing and the concentrations of the two antibiotics present in the samples were determined by HPLC analysis." | ( The pharmacokinetics and sputum penetration of ampicillin and amoxycillin following simultaneous i.v. administration. Harvey, JE; Lovering, AM; Pycock, CJ; Reeves, DS, 1990) | 0.54 |
| " Serum levels of AZT examined were the highest at 30 minutes after dosage (the first sampling) and were 106." | ( [Pharmacokinetic and clinical evaluation of aztreonam in neonates and premature infants]. Kawamura, K; Nakamura, H; Seo, K; Sugita, M; Toyonaga, Y, 1990) | 0.28 |
| " The mean serum level at 6 hours after dosage was 13." | ( [Pharmacokinetic and clinical studies on aztreonam in neonates]. Nishimura, T; Tabuki, K, 1990) | 0.28 |
| " Average daily dosage of AZT 46." | ( [Pharmacokinetic and clinical evaluations of aztreonam monotherapy and aztreonam and ampicillin combination therapy in neonates and premature infants]. Aramaki, M; Kawakami, A; Koga, T; Motohiro, T; Oda, K; Sakata, Y; Shimada, Y; Tanaka, K; Tominaga, K; Tomita, S, 1990) | 0.5 |
| " Therefore, development of dosage regimens providing the drug efficient concentrations in tissues and organs of the urinary tract should be based on ampicillin kinetics in the blood." | ( [Ampicillin pharmacokinetics in prostatic adenoma patients]. Iakovlev, VP; Lur'e, LA; Nekhorosheva, AG; Skala, LZ; Slobodskoĭ, RA, 1987) | 1.38 |
| " The fractional urinary excretion of ampicillin in the first 8 hours after dosing was less than 1 per cent of the dose by all three routes." | ( Bioavailability, disposition kinetics and renal clearance of ampicillin following three routes of administration in sheep. Hafeez, M; Iqbal, T; Khan, FH; Nawaz, M; Nawaz, R, 1989) | 0.79 |
| " For combined ampicillin/sulbactam dosage forms the ratios of 1:1 to 2:1 should be recommended." | ( [Kinetics of the antibacterial effect of ampicillin and sulbactam combinations in dynamic and static conditions]. Chernykh, VM; Firsov, AA; Nazarov, AD; Samoĭlova, LN; Treskina, OS, 1989) | 0.9 |
| " Indirect effects examined include colonization of the gastrointestinal tract, competition with the resident microbiota, and translocation of the dosed microorganisms to other organs." | ( Effect of ampicillin-induced alterations in murine intestinal microbiota on the survival and competition of environmentally released pseudomonads. Claxton, LD; George, SE; Stead, AG; Walsh, DB, 1989) | 0.68 |
| ", either dosed once 30 h before marrow preparation, or dosed twice 48 and 24 h before marrow preparation)." | ( In vitro and in vivo cytogenetic studies of three beta-lactam antibiotics (penicillin VK, ampicillin and carbenicillin). Gatehouse, D; Pascoe, S; Stemp, G, 1989) | 0.5 |
| " No adverse side-effects were reported and dosage adjustment was not required in the elderly." | ( Clinical efficacy of sulbactam/ampicillin in the treatment of moderately severe bacterial infections. Boey, ML; Feng, PH; Fong, KY; Howe, HS, 1989) | 0.56 |
| " PGF-2 alpha treatment lasted 2-26 days and dosage varied from 26." | ( A retrospective study of 40 cases of canine pyometra-metritis treated with prostaglandin F-2 alpha and broad-spectrum antibacterial drugs. Gilbert, RO; Nöthling, JO; Oettle, EE, 1989) | 0.28 |
| " The daily dosage was about 40 mg/kg body weight in each case and the duration of treatment was 10 days." | ( Clinical efficacy and tolerance of bacampicillin and amoxycillin suspensions in children with acute otitis media. Bondesson, G; Haapaniemi, J; Puhakka, HJ; Tuohimaa, P, ) | 0.4 |
| " When administering combinations of antibiotics non-simultaneous dosing is superior to simultaneous administration." | ( [The kinetics of bacterial killing by fluctuating concentrations of antibiotics]. Allerberger, F; Bonatti, H; Dierich, MP; Guggenbichler, JP; Semenitz, E, 1989) | 0.28 |
| " Several factors support such usage: 1) the superiority of sultamicillin compared with the ampicillin commercial dosage form as a delivery system for ampicillin; 2) the possible occurrence at the infection site of beta-lactamase-producing organisms, not themselves pathogens, which nevertheless impair the activity of the beta-lactam antibiotic against sensitive pathogens; 3) the complementary binding of penicillin-binding proteins by ampicillin and sulbactam in ampicillin-sensitive organisms; 4) the lack of resistance development following repeated exposure of strains sensitive to sulbactam/ampicillin suggested by in vitro studies; and 5) the inability of sulbactam to induce beta-lactamase production." | ( Worldwide clinical experience with sultamicillin. Gilbert, GS; Knirsch, AK; Noguchi, Y; Pitts, NE, 1989) | 0.5 |
| " The most common dosage regimen was 375 mg three times daily." | ( Sultamicillin in the treatment of urinary tract infections. Kawada, Y, 1989) | 0.28 |
| " Further studies in larger groups of patients are needed to clarify the therapeutic efficacy and safety of sultamicillin in comparison with other antibacterial regimens, and to determine the optimum single dosage for the treatment of gonorrhoea." | ( Sultamicillin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Campoli-Richards, DM; Friedel, HA; Goa, KL, 1989) | 0.28 |
| " SBT/ABPC was administered to 14 patients with bronchopneumonia, 4 patients with tonsillitis, a patient each with acute upper respiratory infection, with submandibular lymphadenitis, with phlegmon, with enterocolitis, with pyelonephritis and with cystitis at a daily dosage of 88." | ( [Clinical evaluation of sulbactam/ampicillin in children]. Ito, M; Ito, S; Mayumi, M; Mikawa, H, 1989) | 0.56 |
| " The dosage used was 101." | ( [Pharmacokinetic, bacteriological and clinical studies of sulbactam/ampicillin in pediatric patients]. Aramaki, M; Fujimoto, T; Koga, T; Motohiro, T; Oda, K; Sakamoto, H; Sakata, Y; Shimada, Y; Tanaka, K; Yamashita, F, 1989) | 0.51 |
| " Sulbactam/ampicillin was given by intravenous bolus in a dosage range of 75-450 mg/kg/day in four divided doses for variable periods of time depending on the type and severity of the infection." | ( Intravenous sulbactam/ampicillin in the treatment of pediatric infections. Chen, CM; Chu, ML; Hsu, CY; Huang, LM; Lee, CY; Lee, MJ; Lin, TY, ) | 0.84 |
| " Nine out of every 10 prophylactic administrations of A/A were abnormal owing to incorrect indication (77%), dosage (10%), oral route (62%) or excessive duration (82%)." | ( [Use of aminopenicillins: first cause of error in the prescription of antimicrobial agents at a hospital]. Cartón, JA; Maradona, JA, 1989) | 0.28 |
| " dosage regimen would be appropriate." | ( [Clinical evaluation of sulbactam/ampicillin in the pediatric infections]. Abe, T; Arimasu, O; Fujii, R; Hiruma, F; Mashiko, J; Meguro, H; Nagao, Y; Okamoto, Y; Shiraishi, H; Sugamata, K, 1989) | 0.56 |
| " Twenty pediatric patients with infection were treated with SBT/ABPC and an intravenous dosage of 27." | ( [Bacteriological, pharmacokinetic and clinical studies of sulbactam/ampicillin in the pediatric field]. Haruta, T; Hashimoto, H; Kobayashi, Y; Kuroki, S; Okura, K; Yamaoka, K; Yoshioka, N, 1989) | 0.51 |
| " It was found that piperazine-2,5-dione was also excreted in the urine of a volunteer dosed with ampicillin." | ( A sensitive high performance liquid chromatographic assay of a new metabolite of ampicillin in man. Haginaka, J; Wakai, J, 1986) | 0.72 |
| " In most cases a dosage of 400 mg X 2 was used but in severe cases 800 mg X 2 was used." | ( A multicentre trial with bacampicillin (Penglobe) in the treatment of respiratory tract infections in general practice. Detiège, JJ; Pauwels, R, 1986) | 0.57 |
| " typhimurium illness in immunocompromised mice after long-term oral chemotherapy for 26 days at a dosage of 100 mg/kg twice a day." | ( Oral ciprofloxacin treatment for Salmonella typhimurium infection of normal and immunocompromised mice. Brunner, H; Zeiler, HJ, 1988) | 0.27 |
| " The aims were to determine an appropriate dosage regimen and to study the pharmacokinetics." | ( Pharmacokinetic study of sulbactam and ampicillin administered concomitantly by intraarterial or intravenous infusion in the newborn. Cockburn, F; McAllister, TA; Sutton, AM; Turner, TL, ) | 0.4 |
| " Sulbactam/ampicillin was administered im or iv at a dosage of 3-9 g/day depending on the site and severity of the infection." | ( Clinical efficacy and safety of sulbactam/ampicillin in patients suffering from chronic liver disease. Barba, D; Esposito, S; Galante, D; Ruffilli, MP, 1987) | 0.93 |
| " Due to the nature of the pathogen (in vivo bactericidal concentrations of antibiotics are often not attainable; intracellular growth) a high dosage of ampicillin is recommended." | ( Listeria monocytogenes infections--therapeutic possibilities and problems. Marget, W; Seeliger, HP, 1988) | 0.47 |
| " The optimal multiple dosing time and the minimum critical concentration to achieve antimicrobial action can be readily calculated from the developed model." | ( A pharmacodynamic model for the activity of antibiotics against microorganisms under nonsaturable conditions. Nightingale, CH; Quintiliani, R; Zhi, J, 1986) | 0.27 |
| " The proportion of each species among the enterococcal population changed with time in birds not dosed with antibiotics." | ( The effect of ampicillin and tylosin on the faecal enterococci of healthy young chickens. Hinton, M; Kaukas, A; Linton, AH, 1987) | 0.63 |
| " These results suggest that lower dosage of streptomycin in the therapy of enterococcal infections will probably result in a higher relapse rate." | ( Synergistic effect of ampicillin or vancomycin in combination with decreasing concentrations of streptomycin against enterococci. Fuursted, K, 1988) | 0.59 |
| " The pivampicillin dosage was 700 mg twice a day and the erythromycin dosage 500 mg twice a day for seven days." | ( Pivampicillin compared with erythromycin for treating women with genital Chlamydia trachomatis infection. Cramers, M; From, E; Kaspersen, P; Møller, BR, 1988) | 1.33 |
| " SBTPC fine granules were administered orally to 1 patient with bronchitis, 9 patients with bronchopneumonia, 7 patients with tonsillitis, 4 patients with scarlet fever, 1 patient each with pharyngitis, otitis media, purulent parotitis, and urinary tract infection and 6 patients with skin and soft tissue infections at daily dosage levels of 26." | ( [Clinical evaluation of sultamicillin fine granules in pediatric patients]. Ito, S; Mayumi, M; Mikawa, H, 1988) | 0.27 |
| " The patients included 9 boys and 10 girls from 11 months to 13 years old and they were given orally a dosage of 15." | ( [Clinical study of sultamicillin fine granules]. Kawakami, K; Okada, K; Takeda, E, 1988) | 0.27 |
| " The dosage was 10-30 mg/kg daily." | ( [Efficacy of sultamicillin fine granules in pyoderma, particularly in impetigo contagiosa]. Inoue, Y; Kawashima, T; Tokuda, Y, 1988) | 0.27 |
| " The dosage of this antibiotic had to be changed frequently." | ( Comparison of serum concentrations of ceftazidime and tobramycin in newborn infants. Brorson, JE; Tessin, I; Thiringer, K; Trollfors, B, 1988) | 0.27 |
| " Different types of Pakistani diets ingested immediately before dosing reduced plasma levels to an almost similar extent, while different results were found upon changing the time of drug administration with respect to the food intake." | ( Influence of ethnic diets on ampicillin bioavailability and pharmacokinetics in healthy Pakistani subjects. Beg, AE; Hamid, S, ) | 0.42 |
| " The aim was to evaluate the efficacy and safety of bacampicillin in a twice daily dosage, compared with three times daily dosages of bacampicillin, ampicillin, amoxycillin and a twice daily dosage of co-trimoxazole." | ( The clinical efficacy and safety of bacampicillin twice daily in comparative studies. Blomqvist, M; Hedström, SA, ) | 0.65 |
| " References to indication and dosage of several chemotherapeutics are given on the basis of recent knowledge of liquor metabolism as well as clinical and experimental findings." | ( [Acute bacterial meningitis in adults--a therapeutic problem]. Bernasowski, A; Kunze, M, 1986) | 0.27 |
| " To control the development of aminoglycoside resistance in hospitals, it may be necessary to restrict the use of more than the one drug to which resistance is developing; to use the antibiotic at the right dosage and, when necessary, in a combination that may prevent the emergence of resistant organisms and plasmids; and to develop measures to control bacterial and R factor transmission." | ( Strategies in aminoglycoside use and impact upon resistance. Acar, JF; Bleriot, JP; Goldstein, FW; Menard, R, 1986) | 0.27 |
| " Since serum and tissue concentrations of Mb-12 after 200 mg administration in humans have been reported to be 1-2 micrograms/ml, it can be presumed that the causative bacteria would be eradicated by a usual dosage of MOM used in the present study." | ( [Midecamycin acetate-susceptibility of clinical isolates from dental and oral surgical infections]. Deguchi, K; Fukayama, S; Ikegami, R; Matsumoto, Y; Nishimura, Y; Oda, S; Sato, K; Tanaka, S; Yokota, N; Yoshihara, H, 1986) | 0.27 |
| " However, significant body weight reduction and mortality occurred with the two higher dosage regimens." | ( An evaluation of ampicillin pharmacokinetics and toxicity in guinea pigs. Hurst, WJ; Lang, CM; White, WJ; Young, JD, 1987) | 0.61 |
| "The dose-response relationship between the frequencies or concentration of exposure to powdered drug allergens and drug induced allergic onsets was studied in a pharmaceutical plant for 15 years from 1974 to 1984." | ( [A study on dose-response relationship of occupational allergy in a pharmaceutical plant]. Chida, T, 1986) | 0.27 |
| " On the base of the changes established in the pharmacokinetic parameters ampicillin-trihydrate was dosed for use via the drinking water as follows: 196 mg/l simultaneously with flavophospholipol in the feed, 156 mg/l--with the use of vitamycin A, 148 mg/l--when used with the A-149 antibiotic, and 216 mg/l--when administered at no medication via the feed." | ( [Effect of feed antibiotics on ampicillin pharmacokinetics in chickens]. Mutafchieva, R; Pashov, D, 1986) | 0.79 |
| " A total daily dosage of 300 mg/kg or 9 gm/m2 given in four to six divided dosages should produce peak concentrations of approximately 150 micrograms/ml, and concentrations greater than 16 micrograms/ml for at least 2 hours after each administration." | ( Clinical pharmacology of extended-spectrum penicillins in infants and children. Koup, JR; Wilson, CB, 1985) | 0.27 |
| " From these results the recommended dosage is: 20 mg/kg twice daily for premature, dysmature and full term neonates up to 8 days, 30 mg/kg twice daily for infants from 8 days to one month of age, and 30 mg/kg three or four times a day for infants above one month of age." | ( [Pharmacokinetics of apalcillin in pediatrics]. Akbaraly, JP; Heinzel, G; Martin, C; Peyraud, J; Sarlangue, J; Sautarel, M, 1985) | 0.27 |
| " A dosage of 200 mg/kg/day should allow the treatment of meningitis due to sensitive bacteria and in particular due to Pseudomonas aeruginosa." | ( Meningeal penetration of apalcillin in man. Akbaraly, R; Auzerie, J; Bedjaoui, A; Casanova, P; Gallias, H; Raoult, D, 1985) | 0.27 |
| "Escherichia coli ATCC 12407 was exposed in an in-vitro kinetic model to multiple dose ampicillin regimens differing in simulated drug elimination half-life but with equal dosage intervals and similar dose levels." | ( Influence of ampicillin elimination half-life on in-vitro bactericidal effect. Toothaker, RD; White, CA, 1985) | 0.86 |
| " It was confirmed that a large number of microcapsules still remained in the stomach and each microcapsules still contained ampicillin at 24 h after dosing from the experiment using gastric-emptying-controlled rabbits." | ( Preparation and biopharmaceutical evaluation of microcapsules of ampicillin. Aoyama, T; Goto, S; Uchida, T, 1985) | 0.71 |
| "Clinical evaluation of newly developed oral ampicillin prodrug lenampicillin (LAPC, KBT-1585) applied to patients with superficial purulent infection at a dosage of 750 approximately 1,500 mg daily was conducted." | ( [Clinical studies on lenampicillin in the therapy of skin and soft tissue infections]. Fujita, K; Horie, N; Katsumata, M; Kubota, Y; Kukita, A; Miura, Y; Nonami, E; Takahashi, H; Takeshima, M; Watanabe, S, 1985) | 0.84 |
| " On the other hand, high levels of acetoin were found out in portal plasma for early period after dosing of LAPC." | ( [Metabolism of lenampicillin hydrochloride. II. Metabolism of promoiety]. Aoyama, T; Awata, N; Noumi, K; Takaki, A; Uemura, Y, 1985) | 0.6 |
| " The cerebrospinal fluid bactericidal titers obtained 16 to 24 h after ceftriaxone dosing were usually 1:512 to greater than 1:2,048 even late in the treatment course, compared with values of 1:8 to 1:32 in patients receiving ampicillin plus chloramphenicol." | ( Comparison of ceftriaxone and ampicillin plus chloramphenicol for the therapy of acute bacterial meningitis. Bryan, JP; da Silva, HR; Rocha, H; Sande, MA; Scheld, WM; Taveres, A, 1985) | 0.74 |
| " A study has been made of serum, mixed and parotid salivary levels attained in normal volunteers following oral dosage of 500 mg phenoxymethylpenicillin tablets, 500 mg crushed phenoxymethylpenicillin tablets in capsules, 500 mg ampicillin, 500 mg cloxacillin and 500 mg cephalexin." | ( Comparison of human serum, parotid and mixed saliva levels of phenoxymethylpenicillin, ampicillin, cloxacillin and cephalexin. Speirs, CF; Stenhouse, D; Stephen, KW; Wallace, ET, 1971) | 0.66 |
| " Peritoneal dialysis does not alter these dosage requirements." | ( The effects of peritoneal dialysis on the physiological disposition of oxacillin, ampicillin and tetracycline in patients with renal disease. Ruedy, J, 1966) | 0.47 |
| " All volunteers were dosed with both bacampicillin and cefuroxime axetil under the above regimens." | ( Influence of food and reduced gastric acidity on the bioavailability of bacampicillin and cefuroxime axetil. Moncrieff, J; Schoeman, HS; Sommers, DK; van Wyk, M, 1984) | 0.77 |
| " Two dosage schedules were investigated, both resulting in the same total daily dosage (1500 mg sultamicillin)." | ( Sultamicillin (CP-49, 952): evaluation of two dosage schedules in urinary infection. Ball, AP; Fox, C; Ghosh, D, 1984) | 0.27 |
| " These results differ from earlier findings that the concentration of ampicillin in the CSF of rabbits was significantly lower in animals concomitantly dosed with latamoxef (moxalactam) and ampicillin than in a group dosed only with ampicillin." | ( Cerebrospinal fluid penetration after combined administration of cefotaxime and ampicillin to rabbits with staphylococcal meningitis. Haruta, T; Kobayashi, Y; Okura, K, 1984) | 0.73 |
| " Ampicillin has been administered intravenously at the dosage of 1-6 g daily." | ( Rashes associated with intravenous administration of ampicillin. Esposito, S; Galante, D; Lettieri, G; Scioli, C, 1983) | 1.43 |
| " This work holds considerable promise for the study of dosage adjustments in patients with renal disease." | ( Quantitative investigation of renal handling of drugs in dogs with renal insufficiency. Hori, R; Kamiya, A; Okumura, K, 1984) | 0.27 |
| " But in some patients a dosage of 5-7 mg/kg/d of gentamicin is too low, while others show concentrations near to the toxic levels." | ( [Pharmacokinetics of combined antibiotic therapy in the newborn infant]. Bergt, U; Heimann, G; Schug, S, 1983) | 0.27 |
| " The dosage of pivamdinocillin in adults was 400 to 800 mg, every 6 hours, for 10 to 16 days; dosage in children was half this amount for 11 to 15 days." | ( Management of enteric fever with amdinocillin. Ball, AP; Geddes, AM, 1983) | 0.27 |
| " One patient in each dosage group discontinued the medication because of severe diarrhoea." | ( Clinical, bacteriological and pharmacokinetic results from an open trial of sultamicillin in patients with acute exacerbations of chronic bronchitis. Davies, BI; Maesen, FP; van Noord, JA, 1984) | 0.27 |
| " In their concluding remarks the authors state that in addition to being effective in the morbid condition selected for trial, cotrimazine offers some advantages over similar combinations of TMP and other sulfonamides, both because of the intrinsic physicochemical and pharmacological properties of SDZ and because of its lower dosage in this combination." | ( A clinical trial of co-trimazine (sulfadiazine + trimethoprim) in flare-ups of chronic bronchitis. Lanza, R; Leone, G; Paoletti, V; Parlapiano, C; Vincentelli, GM, 1984) | 0.27 |
| "The evaluation of a 10-day 3 x 800 mg dosage regimen was equivalent for bacampicillin to oral ampicillin therapy (using 3 or 4 g respectively per day) in patients with primary UTI (n = 50) in clinical and bacteriological respect." | ( [Bacampicillin in urinary tract infections tolerance in patients with impaired kidney and liver function]. Ezold, R; Kleint, V; Tauchnitz, C, 1984) | 1.06 |
| " Serum gentamicin concentration should be assayed about three half-lives after start of infusion and the dosage adjusted for values outside 3-5 micrograms/ml." | ( Kinetics and dose calculations of ampicillin and gentamicin given as continuous intravenous infusion during parenteral nutrition in 88 newborn infants. Bentzon, MW; Colding, H; Møller, S, 1983) | 0.54 |
| " to 36 newborn infants using a dosage schedule and the results were compared with those obtained in an earlier study including 88 infants who received individually calculated dosages." | ( Continuous intravenous infusion of ampicillin and gentamicin during parenteral nutrition to 36 newborn infants using a dosage schedule. Andersen, GE; Colding, H; Møller, S, 1984) | 0.54 |
| " A procedure was developed for investigation of the penicillins either in the pure state or in dosage forms." | ( Polarographic behaviour and determination of some penicillins after bromometric oxidation. Abou-Ouf, AA; Belal, F; Rizk, M; Walash, MI, 1984) | 0.27 |
| " Dosage regimens were allocated randomly." | ( Prophylactic regimens in colorectal surgery. Comparison between metronidazole used alone or in combination with either ampicillin or doxycycline. Andenaes, K; Bergan, T; Bjerkeset, T; Brabrand, G; Erichsen, H; Flørenes, T; Garberg, O; Glauer, H; Holter, O; Roland, M, 1984) | 0.48 |
| " Our results indicate that dosage adjustment based on creatinine clearance is not appropriate for patients receiving drugs requiring active tubular secretion for urinary excretion." | ( Ampicillin and cephalexin in renal insufficiency. Hori, R; Kamiya, A; Nakano, H; Nihira, H; Okumura, K, 1983) | 1.71 |
| "6%, without the influence of patients ages and dosage level." | ( [Experimental and clinical evaluation of an ampicillin suppository (KS-R1) in children]. Fujimoto, T; Ishimoto, K; Koga, T; Kuda, N; Motohiro, T; Nishiyama, T; Sakata, Y; Shimada, Y; Tanaka, K; Tomita, N, 1983) | 0.53 |
| " The kinetic behavior of cefuroxime axetil and ampicillin was not influenced by repeated dosing at 250 mg." | ( Pharmacology of Cefuroxime as the 1-acetoxyethyl ester in volunteers. Ayrton, J; Harding, SM; Williams, PE, 1984) | 0.52 |
| "The relative bioavailability of sarpicillin (the methoxymethyl ester of hetacillin) from three different oral dosage forms was compared in humans employing a three-way crossover study design." | ( Evaluation of the bioavailability of sarpicillin, the methoxymethyl ester of hetacillin, in humans. Hottendorf, GH; Martin, A; Newburger, J; Pearlman, RS; Schneider, LW; Smyth, RD; Stavchansky, S; Van Harken, DR, 1984) | 0.27 |
| "Pharmacokinetics of dicloxacillin and ampicillin dosed individually and in combination were investigated by means of moment analyses of urinary excretions of intact forms and metabolic products of parent penicillins." | ( Comparative pharmacokinetics of dicloxacillin and ampicillin between individual and combined doses. Murai, Y; Nakagawa, T; Uno, T; Yamaoka, K, 1984) | 0.79 |
| " This allows recommending anhydrous ampicillin for preparation of oral dosage forms." | ( [Kinetics of ampicillin breakdown in the solid state]. Nacheva, RN; Ovcharova, GD, 1984) | 0.91 |
| " The results obtained show that increasing the dosage has no effect on apalcillin pharmacokinetics, which appear linear." | ( [Pharmacokinetics of apalcillin. Study of linearity]. Akbaraly, JP; Auzerie, J; Bebear, C; Brachet-Liermain, A; Coux, C; Guyot, M; Heinzel, G; Quentin, C, 1984) | 0.27 |
| " Twice daily dosing (pulse dosing) with bacampicillin has been shown in numerous clinical trials to be of equivalent efficacy to ampicillin given four times daily or amoxicillin given three times daily in the treatment of infections of the upper respiratory tract, lower respiratory tract, skin and soft tissues, and urinary tract." | ( Bacampicillin hydrochloride: chemistry, pharmacology, and clinical use. Neu, HC; Scheife, RT, ) | 1.02 |
| " Intensive dosing schedules were employed to achieve maximal therapeutic benefits with short-term treatment." | ( Comparison of cefamandole, cephalothin, ampicillin, and chloramphenicol in experimental Escherichia coli meningitis. Allen, JC; Beam, TR, 1980) | 0.53 |
| " Of the 493 women in the study, 254 received dosed of 2 million IU of penicillin G intermuscularly 1/2 hour before and 3 hours after the procedure, followed by 350 mg of pivampicillin 3 times daily for 4 days, and 239 women received corresponding doses of placebo." | ( Prophylactic antibiotics in first-trimester abortions: a clinical, controlled trial. Andersen, JT; Dyring-Andersen, K; Hebjøorn, S; Heisterberg, L; Hejl, BL; Sonne-Holm, S, 1981) | 0.46 |
| "The safety and clinical efficacy of dosing twice a day with bacampicillin was evaluated in clinical trials conducted at various locations in Latin America, Switzerland, and Scandinavia, Bacampicillin (200, 400, 600, or 800 mg) given twice a day was compared with bacampicillin (400 mg) or ampicillin (500 or 556 mg) administered three times a day in eight double-blind and six open randomized trials involving 750 patients with respiratory and urinary tract infections." | ( Worldwide experience with bacampicillin administered twice a day. Craig, WA; Gerber, AU, ) | 0.66 |
| " Parenteral aminoglycoside antibiotics in usual dosage did not change the pharyngeal flora." | ( Changes in aerobic pharyngeal flora related to antibiotic use and the emergence of gram-negative bacilli. Fujita, K; Maruyama, S; Oka, R; Yoshioka, H, 1982) | 0.26 |
| " A smaller dosage of talampicillin than ampicillin is required, the drug is better tolerated by the patient, and the time of nursing staff is saved." | ( Treatment of uncomplicated gonorrhoea in women with talampicillin in a single oral 1.5 g dose. Mohanty, KC; Roy, RB, 1982) | 0.82 |
| "Six adult mares were given a single dose of ampicillin trihydrate (250 mg/ml) intramuscularly at a dosage of 20 mg/kg body weight." | ( Body fluid concentrations of ampicillin trihydrate in 6 horses after a single intramuscular dose. Brown, MP; Farver, TB; Kelly, RH; Stover, SM, 1982) | 0.82 |
| " The model was used to study the effects of a multiple intravenous bolus dosage regimen of ampicillin on Escherichia coli ATCC 12407." | ( An in vitro model for the study of antibacterial dosage regimen design. Craig, WA; Toothaker, RD; Welling, PG, 1982) | 0.48 |
| " The mean residence time (MRT), mean absorption time (MAT), mean dissolution time (MDT), and mean disintegration time (MDIT) are calculated for several dosage forms of ampicillin." | ( Moment analysis for the separation of mean in vivo disintegration, dissolution, absorption, and disposition time of ampicillin products. Nakagawa, T; Tanigawara, Y; Uno, T; Yamaoka, K, 1982) | 0.67 |
| " With this data it was possible to calculate the reduced loading and maintenance dose for a certain creatinine clearance and a certain dosage interval to avoid accumulation." | ( [A dosage regimen for epicillin in renal impairment (author's transl)]. Humair, L; Kienel, G; Modde, H, 1981) | 0.26 |
| "The efficacy and tolerance of two different dosage regimens of pivampicillin was compared in 155 patients with acute sinusitis and in 56 patients with otitis media." | ( Treatment of sinusitis and otitis media with pivampicillin. Christensen, CH; Hartmann, E, 1980) | 0.75 |
| "The purpose of the study was to select the minimum effective dose of bacampicillin in a systematic dose-response study in hospitalised patients with acute exacerbations of chronic bronchitis." | ( Bacampicillin twice daily: a dose-response study in acute exacerbations of chronic bronchitis. Davies, BI; Maesen, FP; Sjövall, J, 1981) | 1.12 |
| "Bioavailability of various ampicillin dosage forms was studied." | ( [Bioavailability of ampicillin preparations for internal use]. Batuashvili, TA; Shchedrin, VI; Zak, AF, 1980) | 0.88 |
| " The dosage of antibiotics was 100 mg/kg/day in four equally divided doses given for five days." | ( Treatment of Salmonella gastroenteritis with ampicillin, amoxicillin, or placebo. Jackson, LH; Kusmiesz, H; Nelson, JD; Woodman, E, 1980) | 0.52 |
| " To obtain the same ratio between ampicillin serum levels and MIC (minimum inhibitory concentration) in the pregnant as in the non-pregnant subject, a double dosage should be used." | ( Study of ampicillin levels in maternal serum, umbilical cord serum and amniotic fluid following administration of pivampicillin. Hagen, AG; Jordheim, O, 1980) | 0.96 |
| " Duration of treatment with appropriate dosage should be at least 10 days." | ( [The therapy of urinary tract infections in sows]. Sobestiansky, J; Wendt, M, 1995) | 0.29 |
| "Increasing the dosing interval for T-C in patients with end-stage renal disease may lead to periods of insufficient clavulanic acid to protect ticarcillin from beta-lactamase degradation." | ( Comparison of ampicillin-sulbactam and ticarcillin-clavulanic acid in patients with chronic renal failure: effects of differential pharmacokinetics on serum bactericidal activity. Butler, SC; Hardin, TC; Jorgensen, JH; Ross, S; Wakeford, JH, ) | 0.49 |
| "Ampicillin was embedded in a chitosan matrix to develop an oral release dosage form." | ( Chitosan matrix for oral sustained delivery of ampicillin. Chandy, T; Sharma, CP, 1993) | 1.99 |
| "Because pregnancy is associated with more rapid elimination of beta-lactam drugs, physicians treating infections in pregnant or newly parturient women should consider using shorter intervals between antibiotic doses when a range of dosage intervals is under consideration." | ( Pharmacokinetics of ampicillin and sulbactam in pregnancy. Bawdon, R; Chamberlain, A; Larsen, B; Thomas, S; White, S, 1993) | 0.61 |
| " Against the borderline oxacillin-susceptible strain BOSSA-1, increasing the sulbactam dosage from 500 to 2,000 mg/kg/day while maintaining a fixed dose of ampicillin (1,000 mg/kg/day) by continuous infusion resulted in lower bacterial counts (4." | ( Activity of ampicillin-sulbactam and oxacillin in experimental endocarditis caused by beta-lactamase-hyperproducing Staphylococcus aureus. Eliopoulos, GM; Moellering, RC; Pefanis, A; Thauvin-Eliopoulos, C, 1993) | 0.86 |
| " Subsequent dosing with 5-FU induced lethal septicaemia caused by the inoculated strains in most of these mice, whereas CY did not regularly induce septicaemia." | ( Experimental endogenous septicaemia caused by Klebsiella pneumoniae and Escherichia coli in mice. Furuya, N; Hirakata, Y; Matsumoto, T; Tateda, K; Yamaguchi, K, 1996) | 0.29 |
| " Dosing of LEA at 2400, when the animals were active, resulted in a 50% decrease in mean residence time (MRT) and a 20% increase in systemic clearance (Cltotal)." | ( Chronokinetics of liposomal encapsulated ampicillin in fasting and nonfasting rats. Pardue, RL; White, CA, 1996) | 0.56 |
| "Ampicillin trihydrate or amoxicillin trihydrate was administered at an extra-label dosage of 22 mg/kg of body weight, IM, once to each of 6 cows/drug." | ( Ampicillin and amoxicillin residue detection in milk, using microbial receptor assay (Charm II) and liquid chromatography methods, after extra-label administration of the drugs to lactating cows. Anderson, KL; Moats, WA; Papich, MG; Rushing, JE; Wesen, DP, 1996) | 3.18 |
| "Even at an extra-label dosage of 22 mg/kg, IM, milk residues > 10 ppb (the FDA tolerance value) were not detected beyond the label milk withholding times for ampicillin (48 hours) and amoxicillin (96 hours)." | ( Ampicillin and amoxicillin residue detection in milk, using microbial receptor assay (Charm II) and liquid chromatography methods, after extra-label administration of the drugs to lactating cows. Anderson, KL; Moats, WA; Papich, MG; Rushing, JE; Wesen, DP, 1996) | 1.93 |
| " It was concluded that the similarity in the disposition and elimination of both drugs in sheep and goats indicated that the combination preparation could be administered at the same dosing rate in both species." | ( Comparative pharmacokinetics of an ampicillin/sulbactam combination administered intramuscularly in lactating sheep and goats. Cárceles, CM; Escudero, E; Espuny, A; Vicente, MS, 1996) | 0.57 |
| " The dosing interval of gentamicin did not significantly affect (q." | ( Treatment of experimental endocarditis due to Enterococcus faecalis using once-daily dosing regimen of gentamicin plus simulated profiles of ampicillin in human serum. Almirante, B; Capdevila, JA; Cardona, PJ; Crespo, E; Gavaldà, J; Laguarda, M; Pahissa, A; Pigrau, C; Pou, L, 1996) | 0.5 |
| "The drugs were administered intragastrically to the horses at a dosage equimolar to 15 mg of ampicillin/kg of body weight." | ( Oral bioavailability and in vitro stability of pivampicillin, bacampicillin, talampicillin, and ampicillin in horses. Ensink, JM; Fluitman, MA; Tukker, JJ; van Miert, AS; Vulto, AG; Winkel, MB, 1996) | 0.77 |
| "An in vitro pharmacokinetic model (IVPM) and a mouse model of lethal bacteremia were used to compare the pharmacodynamics of ampicillin-sulbactam when the two components were dosed simultaneously and in sequence against TEM-1-producing Escherichia coli." | ( Efficacy of ampicillin-sulbactam is not dependent upon maintenance of a critical ratio between components: sulbactam pharmacokinetics in pharmacodynamic interactions. Alexov, M; Lister, PD; Sanders, CC, 1996) | 0.88 |
| " bolus dosing were determined by reverse phase HPLC." | ( The disposition of five therapeutically important antimicrobial agents in llamas. Christensen, JM; Hollingshead, N; Murdane, SB; Smith, BB, 1996) | 0.29 |
| " Concentrations in TCF remained above the minimum inhibitory concentration of Streptococcus zooepidemicus for the proposed dosing intervals of 8, 12 and 24 h for ampicillin sodium, pivampicillin and procaine penicillin G respectively." | ( Distribution of penicillins into subcutaneous tissue chambers in ponies. Barneveld, A; Ensink, JM; Klein, WR; Tukker, JJ; Van Miert, AS; Vulto, AG, 1996) | 0.49 |
| "Some pharmacokinetic parameters of an ampicillin/sulbactam (2:1) combination were studied in six goats, after intravenous and intramuscular injection at a single dosage of 20 mg/kg bodyweight (13." | ( Some pharmacokinetic parameters of ampicillin/sulbactam combination after intravenous and intramuscular administration to goats. Carceles, CM; Escudero, E; Espuny, A; Vicente, MS, 1996) | 0.84 |
| " Although the use of steroids as adjunctive therapy for bacterial meningitis has been found to be beneficial, the dosage of dexamethasone administered in our cases may not be enough to suppress the synthesis and release of the cytokines." | ( [Two cases of severe bacterial meningitis with paranasal sinusitis followed by cerebrovascular disease--pathophysiology and treatment of cerebrovascular disease]. Matsukura, S; Miyazato, M; Nagata, N; Ohi, T; Sugimoto, S, 1996) | 0.29 |
| " Serum bactericidal titers were determined and used to calculate the duration of measurable bactericidal activity over the dosing interval of each of the regimens against two clinical isolates of Bacillus fragilis, Escherichia coli, Enterococcus faecalis, and Pseudomonas aeruginosa." | ( Comparison of the bactericidal activities of piperacillin-tazobactam, ticarcillin-clavulanate, and ampicillin-sulbactam against clinical isolates of Bacteroides fragilis, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa. Klepser, ME; Marangos, MN; Nicolau, DP; Nightingale, CH; Quintiliani, R; Zhu, Z, 1997) | 0.51 |
| " To test these possibilities, 24 hens were dosed for either 1, 2, or 3 d with ampicillin, and the content and pattern of residues in laid eggs were evaluated during and after dosing." | ( Modeling drug residue uptake by eggs: yolks contain ampicillin residues even after drug withdrawal and nondetectability in the plasma. Donoghue, AM; Donoghue, DJ; Gaines, S; Hairston, H; Henderson, M; McDonald, M, 1997) | 0.78 |
| " This method would cause a delay in ampicillin dosing in the treatment of serious bacterial infections and unnecessarily complicate nursing procedures." | ( Effect of time and temperature on inactivation of aminoglycosides by ampicillin at neonatal dosages. Bednarek, FJ; Daly, JS; Dodge, RA; Glew, RH; Keroack, MA; Whalen, M, ) | 0.64 |
| " The findings of this study, provide strong support for ampicillin-liposome formulations as valid dosage forms for this drug that are worthy of further experimental evaluations." | ( Liposome-encapsulated ampicillin: physicochemical and antibacterial properties. Margalit, R; Schumacher, I, 1997) | 0.86 |
| " The response of our patient and the reported in vivo data have implications for future treatment of this pathogen, and may necessitate a reevaluation of susceptibility interpretation guidelines by clinical laboratories, and therapeutic drug dosing by clinicians." | ( Successful treatment of persistent bacteremia due to vancomycin-resistant, ampicillin-resistant Enterococcus faecium. Hacek, DM; Mekonen, ET; Noskin, GA; Peterson, LR, 1995) | 0.52 |
| "Disposition profile of ampicillin (ABPC) among honeybees, larvae, honey and royal jelly in a hive after oral dosing to adult bees was studied." | ( Disposition of ampicillin in honeybees and hives. Hayama, T; Nakajima, C; Nakamura, A; Okayama, A; Sakogawa, T, 1997) | 0.96 |
| " The dosage of beta-lactamase during the exponential growth phase has revealed that the strain BS3 produces a maximal amount of this enzyme." | ( [Thermophilic bacteria resistant to antibiotics in traditional public baths]. Filali, FR; Frere, JM; Zaid, A; Zekhnini, Z, 1997) | 0.3 |
| "Direct current and differential pulse polarography DPP were used for the determination of three penicillins, namely, ampicillin, benzylpenicillin and carbenicillin, in pure form and in their dosage forms." | ( Polarographic determination of some penicillins through nitrosation. Belal, F; Eid, M; Rizk, MS, 1998) | 0.51 |
| " Dosage intervals between the usual doses of ampicillin can be increased in dehydrated goats and concentrations which were high enough to kill susceptible microorganisms could still be achieved." | ( Pharmacokinetics of ampicillin trihydrate following intravenous administration to water deprived Nubian goats. Abdullah, AS; Elsheikh, HA; Osman Intisar, AM, ) | 0.71 |
| " Standard antibiotic dosing regimens which simulated the pharmacokinetic profile observed in humans were used." | ( Pharmacodynamic comparisons of levofloxacin, ciprofloxacin, and ampicillin against Streptococcus pneumoniae in an in vitro model of infection. Lacy, MK; Lu, W; Nicolau, DP; Nightingale, CH; Quintiliani, R; Tessier, PR; Xu, X, 1999) | 0.54 |
| " The data on the PAE of Unasyn may be of clinical relevance in determining dosage regimens of the drug." | ( Postantibiotic effect of ampicillin/sulbactam against mycobacteria. Harris, EB; Prabhakaran, K; Randhawa, B, 1999) | 0.61 |
| " The interindividual response to omeprazole in intragastric pH elevation under the study dosage had insignificant variations to alter the success of eradication." | ( A three-day course of intravenous omeprazole plus antibiotics for H. pylori-positive bleeding duodenal ulcer. Chi, CH; Jen, CM; Lin, XZ; Sheu, BS; Yang, HB, ) | 0.13 |
| " These findings validate the current NCCLS guideline for predicting synergistic activity against enterococci in strains with usual susceptibility to ampicillin, and suggest that a therapeutic level less than maximal recommended dosing is sufficient when using gentamicin in this setting." | ( Synergistic effect of gentamicin plus ampicillin on enterococci with differing sensitivity to gentamicin: a phenotypic assessment of NCCLS guidelines. Boschman, CR; Dressel, DC; Noskin, GA; Peterson, LR; Postelnick, MJ; Stosor, V; Tornatore-Reuscher, MA; Zembower, T, 1999) | 0.77 |
| " The present observation may improve the efficacy of the protein antigens and DNA vaccines carried in live-attenuated bacteria, and further experiments should be carried out to determine the best antibiotics and dosage regimen to be used, as well as the best carrier system for individual protein antigens and DNA vaccines." | ( Enhancement by ampicillin of antibody responses induced by a protein antigen and a DNA vaccine carried by live-attenuated Salmonella enterica serovar Typhi. Chan, E; Leung, HC; Tsoi, HW; Wong, LP; Wong, SS; Woo, PC; Yuen, KY, 2000) | 0.66 |
| " The proposed method was applied to commercial dosage forms and the results obtained were in good agreement with those given by USP method." | ( Kinetic spectrophotometric determination of ampicillin and amoxicillin in dosage forms. Belal, F; El-Ashry, SM; El-Kerdawy, MM; El-Wasseef, DR, ) | 0.39 |
| " The method is applicable for the assay of the four drugs under investigation in different dosage forms and the results are in good agreement with those obtained by the official method." | ( Spectrophotometric determination of ampicillin, dicluxacillin, flucloxacillin and amoxicillin antibiotic drugs: ion-pair formation with molybdenum and thiocyanate. Mohamed, GG, 2001) | 0.59 |
| " Ampicillin 2 g-sulbactam 1 g every 3 hours was administered based on history of therapeutic failure of traditional dosing in our thermal injury population." | ( Nontraditional dosing of ampicillin-sulbactam for multidrug-resistant Acinetobacter baumannii meningitis. Ackerman, BH; Cawley, MJ; Lee, S; Suh, C, 2002) | 1.53 |
| " The dose-response curves were bell shaped, indicating toxic effects for the sensor strain at high concentrations of beta-lactams." | ( A luminescent Escherichia coli biosensor for the high throughput detection of beta-lactams. Karp, MT; Kurittu, JS; Valtonen, SJ, 2002) | 0.31 |
| " The dosage and duration of treatment were correct in only 6% of cases." | ( Drugs in the parallel market for the treatment of urethral discharge in Dakar: epidemiologic investigation and physicochemical tests. Ba, C; Badiane, M; Gueye, TS; Sow, PS; Sy, E; Toure, L, 2002) | 0.31 |
| "The pharmacokinetics of a 2:1 ampicillin-sulbactam combination in six rabbits, after intravenous and intramuscular injection at a single dosage of 20 mg/kg bodyweight (13." | ( Pharmacokinetics of an ampicillin/sulbactam (2:1) combination in rabbits. Cárceles, CM; Escudero, E; Serrano, JM; Vicente, MS, 2002) | 0.91 |
| " A dose-response effect of TRBL on ampicillin concentrations in the jejunal samples could be observed." | ( Enzymic degradation of a beta-lactam antibiotic, ampicillin, in the gut: a novel treatment modality. Harmoinen, J; Koski, P; Laitinen, O; Lindevall, K; Syrjänen, K; Vaali, K; Westermarck, E, 2003) | 0.85 |
| " The existence of a correlation between the in vitro drug-release rate (t50%) and viscosity and the lack of a correlation between in vivo and in vitro parameters support the above suggestion and indicate that traditional dissolution rate tests, such as flask-stirrer method, are unsatisfactory as bioavailability indicators when applied to dosage forms that caused marked changes in physiological factors like GER and biliary excretion." | ( Effects of oils and pharmaceutical excipients on the bioavailability of ampicillin orally administered, different oily and aqueous suspensions in rabbit. Alhamami, OM, 2003) | 0.55 |
| " Mice intraperitoneally administered FQ-1 (10 mg/kg) 4, 8, 24, and 48 hours after infection had survival rates as high as 80%, comparable to those of mice treated with norfloxacin at the same dosage and dosing schedule." | ( In vitro and in vivo antipseudomonal activity, acute toxicity, and mode of action of a newly synthesized fluoroquinolonyl ampicillin derivative. Chen, CH; Ji, DD; Lin, WP; Liu, YT; Shiau, CY; Tang, ST; Tsou, TL; Yang, TC; Yang, YW, 2003) | 0.53 |
| ") administered ampicillin sodium were examined in horses in order to design adequate dosing strategies." | ( Intramuscular dosing strategy for ampicillin sodium in horses, based on its distribution into tissue chambers before and after induction of inflammation. Dobretsberger, M; Ensink, JM; Hierweck, B; Meijer, LA; van den Hoven, R, 2003) | 0.95 |
| "The aim of this study was to validate a simplified high-dosage, extended-interval netilmicin dosage regimen for infants." | ( Validation of a simplified netilmicin dosage regimen in infants. Flaegstad, T; Klingenberg, C; Lier, T; Småbrekke, L, 2004) | 0.32 |
| " Results of the study indicated that polymyxin-E (colistin) has an anti-endotoxic effect and is safe for the dogs with endotoxemia at the dosage used in this study." | ( Evaluation of the anti-endotoxic effects of polymyxin-E (colistin) in dogs with naturally occurred endotoxic shock. Sentürk, S, 2005) | 0.33 |
| " Dosage of Nitric oxide, count of eosinophil, lymphocytes, monocytes, and neutrophils in blood and peritoneal exsudte were done." | ( [Therapeutical and inflammatory response in rats with secondary peritonitis and topical use of ampicilin/sulbactam]. Aguiar, JL; Castro, CM; Kreimer, F; Lacerda, CM; Lisboa Júnior, F; Reis, T, 2005) | 0.33 |
| " Bacterial resistance to common disinfectants was so high that the strains could be killed by big dosage disinfectants." | ( [Molecular epidemilogy, antimicrobial and disinfectant resistance of Escherichia coli 0175:H7 in Shichuan]. Liu, HC; Luan, RS; Zhang, B; Zhang, CW, 2005) | 0.33 |
| " The counts of viable bacteria in the spleen and liver of mice treated with MccJ25 at a total dosage of 3 mg/mouse during either 24 h (0." | ( Efficacy of microcin J25 in biomatrices and in a mouse model of Salmonella infection. Farías, RN; Lopez, FE; Salomón, RA; Vincent, PA; Zenoff, AM, 2007) | 0.34 |
| " Severe obese patients need higher dosage of antibiotics." | ( [Use of antibiotics in colorectal surgery in Denmark]. Frimodt-Møller, N; Jensen, TG; Madsen, H; Pedersen, C; Qvist, N; Salomon, S, 2007) | 0.34 |
| "The aim of this study was to assess the impact of three ampicillin dosage regimens on ampicillin resistance among Enterobacteriaceae recovered from swine feces by use of phenotypic and genotypic approaches." | ( Impact of three ampicillin dosage regimens on selection of ampicillin resistance in Enterobacteriaceae and excretion of blaTEM genes in swine feces. Bibbal, D; Bousquet-Mélou, A; Dupouy, V; Fayet, O; Ferré, JP; Prère, MF; Toutain, PL, 2007) | 0.93 |
| " Therefore the power of this study was not sufficient to definitively prove or disprove bioequivalence and additional studies to describe appropriate dosage regimens for ampicillin trihydrate when administered by NF injection to pigs are warranted." | ( Ampicillin pharmacokinetics in swine following needle-free, intramuscular, and intravenous administration. Apley, MD; Coetzee, JF; Gehring, R; Imerman, PM; Karriker, LA, 2007) | 1.98 |
| " We report a child presenting with ileus, hypothermia and lethargy after receiving supratherapeutic dosing of phenytoin after a concentration miscalculation." | ( Unusual presentation of iatrogenic phenytoin toxicity in a newborn. DeGreeff, J; Lowry, JA; Scalzo, AJ; Vandover, JC, 2005) | 0.33 |
| " Physicians must be aware of inaccuracies in reference manuals that may result in dosing errors." | ( Unusual presentation of iatrogenic phenytoin toxicity in a newborn. DeGreeff, J; Lowry, JA; Scalzo, AJ; Vandover, JC, 2005) | 0.33 |
| " Regardless of the response to penicillin skin testing, patients received the usual 1-day dosage of penicillin and amoxicillin, on 2 separate occasions." | ( Skin testing and oral penicillin challenge in patients with a history of remote penicillin allergy. Confino-Cohen, R; Goldberg, A, 2008) | 0.35 |
| " Dosage was adjusted according to creatinine clearance." | ( Efficacy and safety of high-dose ampicillin/sulbactam vs. colistin as monotherapy for the treatment of multidrug resistant Acinetobacter baumannii ventilator-associated pneumonia. Betrosian, AP; Douzinas, EE; Frantzeskaki, F; Xanthaki, A, 2008) | 0.63 |
| " The proposed method was successfully applied to the determination of ampicillin sodium and amoxicillin in some pharmaceutical dosage forms." | ( Study of the enhancement of a new chemiluminescence reaction and its application to determination of beta-lactam antibiotics. Imani-Nabiyyi, A; Iranifam, M; Sorouraddin, MH, ) | 0.37 |
| " So more attention should be paid to reducing the frequency, times and dosage of antimicrobials, especially third or fourth cephalosporins." | ( Transconjugation and genotyping of the plasmid-mediated AmpC beta-lactamase and extended-spectrum beta-lactamase genes in Klebsiella pneumoniae. Qin, JP; Shi, WF; Zhou, J, 2009) | 0.35 |
| " By reducing the antibiotic dosage to 50%, the side effects produced by antibiotics can be minimized." | ( Preparation, characterization and evaluation of a biopolymeric gold nanocomposite with antimicrobial activity. Chamundeeswari, M; Devi, MP; Jacob, JP; Kumar, MG; Mandal, AB; Sastry, TP; Sobhana, SS, 2010) | 0.36 |
| " Unlike aspirin, the inhibition induced by ampicillin involves both reversible and irreversible mechanisms and is not observed immediately after initial dosing (generally requiring approximately 24 h)." | ( Effect of ampicillin on the bleeding time of neonatal intensive care unit patients. Christensen, RD; Henry, E; Lambert, DK; Sheffield, MJ, 2010) | 1.03 |
| " The method is reproducible, quick, inexpensive, and particularly helpful in determining the drug content in commercial dosage forms." | ( Spectrophotometric determination of penicillins in pure and pharmaceutical formulations using Folin-Ciocalteu reagent. Maheshwari, G; Singh, DK, 2010) | 0.36 |
| " Ampicillin was dosed at every 12 h intravenously, but decisions about discontinuation were made by the responsible clinician, independent of this study." | ( Effect of ampicillin on bleeding time in very low birth-weight neonates during the first week after birth. Baer, VL; Butler, A; Christensen, RD; Henry, E; Lambert, DK; Sheffield, MJ; Snow, GL, 2011) | 1.68 |
| " In all, 10 had ampicillin dosing stopped after a shorter course (4 to 7 doses) and 10 had it continued for a longer course (10 to 15 doses)." | ( Effect of ampicillin on bleeding time in very low birth-weight neonates during the first week after birth. Baer, VL; Butler, A; Christensen, RD; Henry, E; Lambert, DK; Sheffield, MJ; Snow, GL, 2011) | 1.12 |
| " For this reason, the dosage of [corrected] these drugs should be carefully evaluated [corrected] to minimize side effects." | ( Effects of some drugs on human cord blood erythrocyte carbonic anhydrases I and II: an in vitro study. Aktas, M; Cankaya, M; Coban, TA; Gül, İ; Kuzucu, M, 2012) | 0.38 |
| " Recent evidence supports daily rather than three-times-daily dosing of gentamicin for greater efficacy and decreased fetal toxicity." | ( Evidence for the clinical management of chorioamnionitis. Fishman, SG; Gelber, SE, 2012) | 0.38 |
| " Despite its frequent use in intensive care units, there are no available dosing recommendations for patients with AKI undergoing renal replacement therapy." | ( Pharmacokinetics of ampicillin/sulbactam in critically ill patients with acute kidney injury undergoing extended dialysis. Broll, M; Burhenne, H; Burkhardt, O; Clajus, C; Hafer, C; Kaever, V; Kielstein, JT; Knitsch, W; Lorenzen, JM, 2012) | 0.7 |
| " There was no significant accumulation using a twice-daily dosage of 2 g/1 g ampicillin/sulbactam." | ( Pharmacokinetics of ampicillin/sulbactam in critically ill patients with acute kidney injury undergoing extended dialysis. Broll, M; Burhenne, H; Burkhardt, O; Clajus, C; Hafer, C; Kaever, V; Kielstein, JT; Knitsch, W; Lorenzen, JM, 2012) | 0.93 |
| "3 m(2); blood and dialysate flow, 160 ml/min; treatment time, 480 minutes), a twice-daily dosing schedule of at least 2 g/1 g ampicillin/sulbactam, with one dose given after ED, should be used to avoid underdosing." | ( Pharmacokinetics of ampicillin/sulbactam in critically ill patients with acute kidney injury undergoing extended dialysis. Broll, M; Burhenne, H; Burkhardt, O; Clajus, C; Hafer, C; Kaever, V; Kielstein, JT; Knitsch, W; Lorenzen, JM, 2012) | 0.91 |
| " This study aimed to use renal function to determine the most appropriate timing for intraoperative repeated dosing of ampicillin-sulbactam, a commonly used prophylactic antibiotic, to maintain adequate concentrations throughout the course of surgery." | ( Pharmacokinetics of ampicillin-sulbactam and the renal function-based optimization of dosing regimens for prophylaxis in patients undergoing cardiovascular surgery. Iguro, Y; Ikawa, K; Imoto, Y; Ishida, S; Matsumoto, K; Morikawa, N; Okano, Y; Shimodozono, Y; Takeda, Y; Watanabe, E; Yamada, K; Yamamoto, H; Yokoyama, Y, 2012) | 0.91 |
| " In our patient, intraperitoneal dosing of polymyxin B was determined based on limited published pharmacokinetic and pharmacodynamic data." | ( Successful treatment of extensively drug-resistant Acinetobacter baumannii peritoneal dialysis peritonitis with intraperitoneal polymyxin B and ampicillin-sulbactam. Esterly, JS; Fitzpatrick, MA; Postelnick, MJ; Sutton, SH, ) | 0.33 |
| " Results of the part I (internal) and part II (independent laboratory) dose-response studies employing spiked samples were in close agreement." | ( Validation study of the BetaStar plus lateral flow assay for detection of beta-lactam antibiotics in milk. Abouzied, M; Ankrapp, D; Driksna, D; Klein, F; Mozola, M; Rice, J; Sarzynski, M; Walsh, A; Walsh, C, ) | 0.13 |
| " In elderly patients without renal impairment and/or in severe infection with less susceptible pathogens, more frequent dosing of ampicillin 2 g/sulbactam 1 g can be necessary to avoid the risk of underdosing in CAP." | ( Ampicillin/sulbactam in elderly patients with community-acquired pneumonia. Drewelow, B; Frimmel, S; Klammt, S; Loebermann, M; Majcher-Peszynska, J; Mundkowski, RG; Reisinger, EC; Welte, T, 2014) | 2.05 |
| " The therapeutic challenges for ensuring achievement of optimal dosing of SAM result partly from bacterial susceptibility but also from the pharmacokinetic (PK) alterations common to β-lactam agents in critical illness." | ( Ampicillin/sulbactam: its potential use in treating infections in critically ill patients. Adnan, S; Lipman, J; Paterson, DL; Roberts, JA, 2013) | 1.83 |
| " Simulations were performed to investigate the effects of different dosing intervals on exposure and time above MIC in various degrees of renal impairment." | ( Population pharmacokinetics of ampicillin and sulbactam in patients with community-acquired pneumonia: evaluation of the impact of renal impairment. Marshall, S; Muto, C; Shoji, S; Soto, E; Tomono, Y, 2014) | 0.69 |
| " These findings provide useful information and augment evidence for the established dosage regimens in patients with various degrees of renal impairment." | ( Population pharmacokinetics of ampicillin and sulbactam in patients with community-acquired pneumonia: evaluation of the impact of renal impairment. Marshall, S; Muto, C; Shoji, S; Soto, E; Tomono, Y, 2014) | 0.69 |
| "Although ampicillin is the most commonly used drug in neonates, developmental pharmacokinetic (PK) data to guide dosing are lacking." | ( Characterization of the population pharmacokinetics of ampicillin in neonates using an opportunistic study design. Benjamin, DK; Capparelli, EV; Cohen-Wolkowiez, M; Delmore, P; Gao, J; Ian-U Chong, S; Laughon, M; Le, J; Melloni, C; Poindexter, B; Salgado, A; Sullivan, JE; Tremoulet, A, 2014) | 1.07 |
| " There was no significant effect of dosing interval (every 12 vs." | ( Disposition of ampicillin trihydrate in plasma, uterine tissue, lochial fluid, and milk of postpartum dairy cattle. Credille, BC; DiPietro, RO; Ensley, DT; Fishman, HJ; Giguère, S; Jones, AL; Mason, ME; Vickroy, TW, 2015) | 0.77 |
| " Based on this study, milk ampicillin concentrations exceed the minimum inhibitory concentration required to inhibit the growth of 90% of organisms (MIC90) for at least 65% of the dosing interval, which is sufficient for once-daily dosing with most cases of gram-positive mastitis." | ( Short communication: Pharmacokinetics of intramammary hetacillin in dairy cattle milked 3 times per day. Baynes, RE; Lindquist, DA; Smith, GW, 2015) | 0.71 |
| " However, dosing regimens are often extrapolated from data in adults and older children, increasing the risk for drug toxicity and lack of clinical efficacy because they fail to account for developmental changes in infant physiology." | ( New antibiotic dosing in infants. Pineda, LC; Watt, KM, 2015) | 0.42 |
| "A residue depletion study of ampicillin (AMP) was performed after oral dosing (60." | ( Residue depletion of ampicillin in eggs. Dai, GJ; Guo, HS; Li, AH; Wang, JY; Xie, KZ; Xie, X; Zhang, GX; Zhao, M, 2015) | 1.03 |
| " The device provides a new opportunity for on-site therapeutic drug monitoring, which should enable quick and accurate dosing and may save lives in such critical conditions." | ( Electrokinetic Size and Mobility Traps for On-site Therapeutic Drug Monitoring. Breadmore, MC; Guijt, RM; Shallan, AI, 2015) | 0.42 |
| " ABPC residue concentrations in eggs before, during and after 7 days of medicated feeding of maximum dosage (40 mg kg(-1) body weight day(-1)) of ABPC were determined with the LC-MS/MS method." | ( Measurement of ampicillin residue levels in chicken eggs during and after medicated feed administration by LC-MS/MS. Akama, R; Hamamoto, K; Mizuno, Y, 2015) | 0.77 |
| " Animal dosing schedules, the comet assay processing and analysis, and statistical analysis were conducted in accordance with the standard protocol." | ( Use of a standardized JaCVAM in vivo rat comet assay protocol to assess the genotoxicity of three coded test compounds; ampicillin trihydrate, 1,2-dimethylhydrazine dihydrochloride, and N-nitrosodimethylamine. Bellier, PV; McNamee, JP, 2015) | 0.63 |
| " This study aimed to determine the most appropriate timing for intraoperative repeated dosing of ampicillin-sulbactam, a commonly used antibiotic prophylaxis regimen, to maintain adequate concentrations throughout the course of cardiovascular surgery with cardiopulmonary bypass (CPB)." | ( Pharmacokinetics of Prophylactic Ampicillin-Sulbactam and Dosing Optimization in Patients Undergoing Cardiovascular Surgery with Cardiopulmonary Bypass. Ikawa, K; Imoto, Y; Matsumoto, K; Morikawa, N; Takeda, Y; Watanabe, E; Yamamoto, H; Yokoyama, Y, 2015) | 0.92 |
| " The method A was successfully applied to the determination of ampicillin in commercial dosage forms containing equivalent amount of cloxacillin." | ( Circular dichroism spectroscopy: An efficient approach for the quantitation of ampicillin in presence of cloxacillin. Khan, S; Rahman, N, 2016) | 0.9 |
| " Predictions made from the study could be used to redesign multidrug treatment strategies not only for intramuscular treatment in pigs, but also for other dosing routes." | ( Multistrain models predict sequential multidrug treatment strategies to result in less antimicrobial resistance than combination treatment. Ahmad, A; Christiansen, LE; Græsbøll, K; Matthews, L; Nielsen, SS; Olsen, JE; Toft, N; Zachariasen, C, 2016) | 0.43 |
| " Representative results using this protocol are provided by assessing the fitness effects of all single amino acid mutations in TEM-1 at a clinically relevant dosage of ampicillin." | ( A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing. Ranganathan, R; Salinas, VH; Stiffler, MA; Subramanian, SK, 2016) | 0.63 |
| " The results showed that compound 11 exhibited good antibacterial activity against Serratia marcescens compared to the positive control ampicillin at a dosage of 100 μg/disk." | ( Halogenated Sesquiterpenoids from the Red Alga Laurencia tristicha Collected in Taiwan. Chen, JY; Chiou, SF; Huang, CY; Hwang, TL; Lin, YS; Sheu, JH; Wang, WL, 2016) | 0.64 |
| " In specific, by applying various ampicillin concentrations, the lowest effective ampicillin dosage is investigated to secure plasmid stability while lowering adverse ecological effects." | ( Testing plasmid stability of Escherichia coli using the Continuously Operated Shaken BIOreactor System. Ann Chin, L; Büchs, J; Fuchs, S; Müller, C; Regestein, L; Sieben, M; Steinhorn, G, 2016) | 0.71 |
| "This study evaluated how dosing regimen for intramuscularly-administered ampicillin, composition of Escherichia coli strains with regard to ampicillin susceptibility, and excretion of bacteria from the intestine affected the level of resistance among Escherichia coli strains in the intestine of nursery pigs." | ( Modeling the growth dynamics of multiple Escherichia coli strains in the pig intestine following intramuscular ampicillin treatment. Ahmad, A; Christiansen, LE; Græsbøll, K; Matthews, L; Nielsen, SS; Olsen, JE; Toft, N; Zachariasen, C, 2016) | 0.88 |
| " The modeling revealed that short treatment duration resulted in lower levels of resistance and that dosing frequency did not substantially influence the growth of resistant strains." | ( Modeling the growth dynamics of multiple Escherichia coli strains in the pig intestine following intramuscular ampicillin treatment. Ahmad, A; Christiansen, LE; Græsbøll, K; Matthews, L; Nielsen, SS; Olsen, JE; Toft, N; Zachariasen, C, 2016) | 0.65 |
| " Besides dosing factors, epidemiological factors (such as number of competing strains and bacterial excretion) influenced resistance development and need to be considered further in relation to optimal treatment strategies." | ( Modeling the growth dynamics of multiple Escherichia coli strains in the pig intestine following intramuscular ampicillin treatment. Ahmad, A; Christiansen, LE; Græsbøll, K; Matthews, L; Nielsen, SS; Olsen, JE; Toft, N; Zachariasen, C, 2016) | 0.65 |
| "The aim of the study was to assess the effect of 1 g ampicillin prophylactic dosage whether it is as effective as the dosage of 2 g to prevent maternal and neonatal morbidity in a randomized manner." | ( Comparison of two different antibiotic regimens for the prophylaxisis of cases with preterm premature rupture of membranes: a randomized clinical trial. Baktiroglu, M; Baydogan, S; Ilhan, O; Kahramanoglu, I; Kahramanoglu, O; Ozkaya, E; Senol, T; Verit, FF; Yucel, O, 2016) | 0.68 |
| " We studied the conductance signal as a function of both antibiotic treatment time and dosage and demonstrated susceptibility testing within 60 min." | ( Droplet-based non-faradaic impedance sensors for assessment of susceptibility of Escherichia coli to ampicillin in 60 min. Alam, MA; Ebrahimi, A, 2017) | 0.67 |
| " ZMUs may be introduced if an intermediate zone is not appropriate for pharmacokinetic/pharmacodynamic or drug dosing reasons." | ( MASTER: a model to improve and standardize clinical breakpoints for antimicrobial susceptibility testing using forecast probabilities. Blöchliger, N; Böttger, EC; Hombach, M; Keller, PM, 2017) | 0.46 |
| " Beta-lactam chemical instability in plasma can cause misleading pharmacokinetic modeling results, which could impact upon model-based dosing recommendations and the forthcoming era of beta-lactam therapeutic drug monitoring." | ( Development of a Novel Multipenicillin Assay and Assessment of the Impact of Analyte Degradation: Lessons for Scavenged Sampling in Antimicrobial Pharmacokinetic Study Design. Barker, CIS; Johnston, A; Kipper, K; Sharland, M; Standing, JF, 2018) | 0.48 |
| " The β-lactams showed a U-shape dose-response relationship in biofilm prevention." | ( In vitro synergism and anti-biofilm activity of ampicillin, gentamicin, ceftaroline and ceftriaxone against Enterococcus faecalis. Hartung, A; Klinger-Strobel, M; Makarewicz, O; Pletz, MW; Stein, C; Thieme, L, 2018) | 0.74 |
| " Ultrasound reduced the dosage of ampicillin required to impair bacterial viability." | ( Ultrasound affects minimal inhibitory concentration of ampicillin against methicillin resistant Staphylococcus aureus USA300. Artini, M; Barbato, G; Papa, R; Scoarughi, GL; Selan, L; Vrenna, G, 2019) | 1.04 |
| "The objective of the study was to evaluate whether there are differences in the latency from preterm premature rupture of membranes to delivery in patients treated with different dosing regimens of azithromycin vs erythromycin." | ( Azithromycin vs erythromycin for the management of preterm premature rupture of membranes. Bachilova, S; Berghella, V; Heidari, P; Hoffman, MK; Navathe, R; Roman, A; Schoen, CN; Smith, S; Tepper, J; Visintainer, P; Ward, A, 2019) | 0.51 |
| "There was no difference in latency to delivery, incidence of chorioamnionitis, or neonatal outcomes when comparing different dosing regimens of the azithromycin with erythromycin, with the exception of respiratory distress syndrome being more common in the 5 day azithromycin group." | ( Azithromycin vs erythromycin for the management of preterm premature rupture of membranes. Bachilova, S; Berghella, V; Heidari, P; Hoffman, MK; Navathe, R; Roman, A; Schoen, CN; Smith, S; Tepper, J; Visintainer, P; Ward, A, 2019) | 0.51 |
| " AAD model was established using Balb/c mice by gavage with ampicillin for 5 days, followed by a 10-day administration of low, medium, and high dosage of Chinese yam, containing allantoin (4." | ( Chinese yam (Dioscorea opposita Thunb.) alleviates antibiotic-associated diarrhea, modifies intestinal microbiota, and increases the level of short-chain fatty acids in mice. Jin, Q; Jing, P; Liang, T; Shen, C; Zhang, N; Zhang, Y, 2019) | 0.76 |
| " By combining parallel experimental evolution with high-throughput dose-response measurements, we measure phenotypic profiles of collateral sensitivity and resistance for a total of 900 mutant-drug combinations." | ( Pervasive and diverse collateral sensitivity profiles inform optimal strategies to limit antibiotic resistance. Maltas, J; Wood, KB, 2019) | 0.51 |
| " The HFIM system could potentially be used to identify clinically relevant combination dosing regimens for use in a clinical trial evaluating the appearance of resistance to antibacterial drugs." | ( Effect of drug combinations on the kinetics of antibiotic resistance emergence in Escherichia coli CFT073 using an in vitro hollow-fibre infection model. Bekele, A; Gandhi, A; Garimella, N; Hartman, N; Li, X; Sacks, L; Stone, H; Weaver, JL; Zere, T, 2020) | 0.56 |
| "Among 1272 infants meeting inclusion criteria, odds of death 7 or 30 days after the positive blood culture were not consistent with a paradoxical effect across any of the dosing regimens or PK parameters evaluated." | ( Paradoxical Antibiotic Effect of Ampicillin: Use of a Population Pharmacokinetic Model to Evaluate a Clinical Correlate of the Eagle Effect in Infants With Bacteremia. Benjamin, DK; Clark, RH; Cohen-Wolkowiez, M; Ericson, JE; Greenberg, RG; Hornik, CP; Le, J; Smith, PB; Tremoulet, AH, 2020) | 0.84 |
| " Single and multiple dosing schemes based on the half-life of ampicillin were applied." | ( In vivo synergism of ampicillin, gentamicin, ceftaroline and ceftriaxone against Enterococcus faecalis assessed in the Galleria mellonella infection model. Hartung, A; Makarewicz, O; Pletz, MW; Thieme, L, 2020) | 1.12 |
| "Ampicillin and ceftriaxone exhibited strain-specific synergistic interactions in the larvae under both dosing regimens, while the other two combinations showed additive effects." | ( In vivo synergism of ampicillin, gentamicin, ceftaroline and ceftriaxone against Enterococcus faecalis assessed in the Galleria mellonella infection model. Hartung, A; Makarewicz, O; Pletz, MW; Thieme, L, 2020) | 2.32 |
| " This is the first study to develop a scheme for differentiation between additive and synergistic effects in larvae and apply a multiple-antibiotic dosing scheme based on the pharmacokinetics of ampicillin." | ( In vivo synergism of ampicillin, gentamicin, ceftaroline and ceftriaxone against Enterococcus faecalis assessed in the Galleria mellonella infection model. Hartung, A; Makarewicz, O; Pletz, MW; Thieme, L, 2020) | 1.07 |
| " In accordance with the results of resistance tests, the patient was treated with intravenous ampicillin at a dosage of 6 g twice daily." | ( Intraperitoneal ampicillin treatment for peritoneal dialysis- related peritonitis with Listeria monocytogenes - a case report. Boss, K; Dolff, S; Dziobaka, J; Kribben, A; Wiegard-Szramek, I, 2020) | 1.12 |
| " In 2019, the American Academy of Pediatrics (AAP) published guidelines for GBS which included updated dosing recommendations for ampicillin for bacteremia and provided specific dosing recommendations for meningitis." | ( Ampicillin Dose for Early and Late-Onset Group B Streptococcal Disease in Neonates. Lim, SY; Miller, JL, 2022) | 2.37 |
| " faecium in an optimized mouse thigh infection model that yields high bacterial growth and allows to define the complete dose-response relationship." | ( A new pharmacodynamic approach to study antibiotic combinations against enterococci in vivo: Application to ampicillin plus ceftriaxone. Jimenez-Toro, I; Otalvaro, JD; Rodriguez, CA; Vesga, O; Zuluaga, AF, 2020) | 0.77 |
| "Increased drug concentrations and slower clearance of ampicillin in azotemic dogs could have clinical importance in contributing to antibiotic associated morbidity requiring indicating the need to adjust ampicillin dosing in dogs with decreased kidney function." | ( Ampicillin pharmacokinetics in azotemic and healthy dogs. Labato, MA; Monaghan, KN; Papich, MG, 2021) | 2.31 |
| "We recommend ampicillin dosage 50 mg/kg q 12 hours for neonates with gestational age ≥32 weeks during the first week of life." | ( Ampicillin Pharmacokinetics During First Week of Life in Preterm and Term Neonates. Hallik, M; Herodes, K; Ilmoja, ML; Kipper, K; Lutsar, I; Metsvaht, T; Oselin, K; Padari, H; Soeorg, H; Tasa, T, 2021) | 2.43 |
| "This study sought to investigate whether dosing frequency (the number of doses per day) affects the antimicrobial efficacy and safety of ampicillin/sulbactam (ABPC/SBT) in Japanese elderly pneumonia patients treated with ABPC/SBT at 6 g/day." | ( Effects of dosing frequency on the clinical efficacy of ampicillin/sulbactam in Japanese elderly patients with pneumonia: A single-center retrospective observational study. Nozawa, K; Sato, H; Sato, VH; Sugiyama, E; Suzuki, H; Suzuki, T; Tajima, M; Takahashi, K; Yoshii, M, 2021) | 1.07 |
| " It is important to optimize the dose and dosing interval of ampicillin-sulbactam because in patients with decreased renal function and low skeletal muscle mass, such as the elderly, excess drug may burden renal function." | ( Dosing Optimization of Ampicillin-Sulbactam Based on Cystatin C in Elderly Patients with Pneumonia. Enoki, Y; Ikawa, K; Matsubara, K; Matsumoto, K; Morikawa, N; Ohshige, T; Shigemi, A; Takeda, Y; Terazono, H; Watanabe, E; Yokoyama, Y, 2021) | 1.17 |
| " Pharmacokinetic/pharmacodynamic (PKPD) modelling and simulations were used to compare single-agent (EUCAST MIC) and combination (chequerboard MIC) target attainment with standard dosing regimens." | ( Simultaneous pharmacokinetic/pharmacodynamic (PKPD) assessment of ampicillin and gentamicin in the treatment of neonatal sepsis. Berkley, JA; Correia, E; Ellis, S; Gastine, S; Kane, Z; Kipper, K; Murunga, S; Nyaoke, B; Obiero, C; Readman, J; Sharland, M; Standing, JF; Thitiri, J; van den Anker, J; Williams, P, 2022) | 0.96 |
| " Simulations showed that feasible dosing strategies would be insufficient to cover resistant strains." | ( Simultaneous pharmacokinetic/pharmacodynamic (PKPD) assessment of ampicillin and gentamicin in the treatment of neonatal sepsis. Berkley, JA; Correia, E; Ellis, S; Gastine, S; Kane, Z; Kipper, K; Murunga, S; Nyaoke, B; Obiero, C; Readman, J; Sharland, M; Standing, JF; Thitiri, J; van den Anker, J; Williams, P, 2022) | 0.96 |
| "We aimed to develop population pharmacokinetic (PK) models of ampicillin and sulbactam using pooled data analysis and to optimize dosing regimens of ampicillin-sulbactam (combination ratio of 2:1) in pediatric patients." | ( Pharmacodynamic Evaluation of Ampicillin-sulbactam in Pediatric Patients Using Plasma and Urine Data. Ikawa, K; Ishihara, N; Morikawa, N; Naora, K; Onita, T; Tamaki, H; Yano, T, 2022) | 1.25 |
| " (Food and Drug Administration-approved maximum dosage in United States) might be better than 45 mg/kg 3 times daily (within approved dosage in Japan) to cover many pathogens." | ( Pharmacodynamic Evaluation of Ampicillin-sulbactam in Pediatric Patients Using Plasma and Urine Data. Ikawa, K; Ishihara, N; Morikawa, N; Naora, K; Onita, T; Tamaki, H; Yano, T, 2022) | 1.01 |
| "Define optimal ampicillin dosing for empiric early-onset sepsis (EOS) therapy in preterm neonates." | ( Ampicillin dosing in premature infants for early-onset sepsis: exposure-driven efficacy, safety, and stewardship. Benjamin, DK; Clark, RH; Cohen-Wolkowiez, M; Greenberg, RG; Le, J; Wade, KC; Yoo, Y; Zimmerman, KO, 2022) | 2.52 |
| " Therefore, selecting suitable excipients for dosage form is an important step in formulation development." | ( Sex-specific and concentration-dependent influence of Cremophor RH 40 on ampicillin absorption via its effect on intestinal membrane transporters in rats. Deng, W; Liu, J; Qin, Y; Shao, H; Yin, H, 2022) | 0.95 |
| " Ampicillin's inconvenient dosing schedule, drug instability, allergy potential, along with ceftriaxone's high risk for Clostridioides difficile infection and its promotion of vancomycin-resistant enterococci (VRE), led our team to explore alternative options." | ( Meropenem plus Ceftaroline Is Active against Enterococcus faecalis in an Cusumano, JA; Daffinee, KE; Desbonnet, C; García-Solache, M; LaPlante, KL; Piehl, EC; Rice, LB, 2022) | 1.63 |
| " Pharmacokinetic data to guide ampicillin dosing in neonates and during the intrapartum period are limited." | ( Foetal and neonatal exposure prediction and dosing evaluation for ampicillin using a physiologically-based pharmacokinetic modelling approach. Li, S; Xie, F, 2023) | 1.43 |
| "A PBPK model was developed to characterize ampicillin's disposition in neonates, pregnant women, and foetuses, and the model supported optimal dosing evaluation in these vulnerable populations." | ( Foetal and neonatal exposure prediction and dosing evaluation for ampicillin using a physiologically-based pharmacokinetic modelling approach. Li, S; Xie, F, 2023) | 1.41 |
| " Only 7 studies reported dosing advice, 4 of which were for amoxicillin." | ( Pharmacokinetics and Target Attainment of Antimicrobial Drugs Throughout Pregnancy: Part I-Penicillins. Hesse, MR; Hooge, MNL; Kosterink, JGW; Mian, P; Prins, JR; Touw, DJ; Winter, HLJ, 2023) | 0.91 |
| "The larger Vd and higher CL in second and third trimester pregnant women might warrant a higher dosage or shortening of the dosing interval of penicillins to increase target attainment." | ( Pharmacokinetics and Target Attainment of Antimicrobial Drugs Throughout Pregnancy: Part I-Penicillins. Hesse, MR; Hooge, MNL; Kosterink, JGW; Mian, P; Prins, JR; Touw, DJ; Winter, HLJ, 2023) | 0.91 |
| "This study investigated the population pharmacokinetics of ampicillin and sulbactam in patients with a wide range of renal functions and sought to define dosing approaches that have a high likelihood for optimising drug exposure." | ( Population Pharmacokinetics and Dosing Simulations of Ampicillin and Sulbactam in Hospitalised Adult Patients. Abdul-Aziz, MH; Cotta, MO; Lukas, DL; Parker, S; Roberts, JA; Setiawan, E; Sosilya, H; Wallis, SC; Widjanarko, D, 2023) | 1.4 |
| " Approved dosing regimens of ampicillin-sulbactam were sufficient against MICs ≤ 8 and ≤ 4 mg/L, respectively." | ( Population Pharmacokinetics and Dosing Simulations of Ampicillin and Sulbactam in Hospitalised Adult Patients. Abdul-Aziz, MH; Cotta, MO; Lukas, DL; Parker, S; Roberts, JA; Setiawan, E; Sosilya, H; Wallis, SC; Widjanarko, D, 2023) | 1.45 |
| "The described dosing regimen for ampicillin/sulbactam is safe with respect to the defined MIC breakpoints for ampicillin, and continuous subtherapeutic concentration is unlikely." | ( Evaluation of continuous ampicillin/sulbactam infusion in critically ill patients. Baehner, T; Passon, SG; Schmidt, AR; Velten, M; Wittmann, M, 2023) | 1.49 |
| " While ampicillin is the preferred agent for the treatment of susceptible Enterococcus faecalis infections, there are no in vivo pharmacokinetic studies regarding ampicillin dosing in patients receiving ECMO." | ( Pharmacokinetics of ampicillin during venovenous extracorporeal membrane oxygenation: A case report. Drummond, W; Elbarbry, F; Footer, BW; Kim, S; Stucky, NL, 2023) | 1.69 |
| Role | Description |
|---|---|
| antibacterial drug | A drug used to treat or prevent bacterial infections. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| beta-lactam antibiotic | An organonitrogen heterocyclic antibiotic that contains a beta-lactam ring. |
| penicillin | Any member of the group of substituted penams containing two methyl substituents at position 2, a carboxylate substituent at position 3 and a carboxamido group at position 6. |
| penicillin allergen | Any penicillin which causes the onset of an allergic reaction. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Pathway | Proteins | Compounds |
|---|---|---|
| Integrated breast cancer pathway | 98 | 18 |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 10.0000 | 0.0032 | 45.4673 | 12,589.2998 | AID2517 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 0.5623 | 0.0447 | 17.8581 | 100.0000 | AID485294; AID485341 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 28.1838 | 0.1778 | 14.3909 | 39.8107 | AID2147 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 19.9526 | 0.1259 | 19.1169 | 125.8920 | AID2549 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 31.6228 | 0.0020 | 14.6779 | 39.8107 | AID1476 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 70.7946 | 14.1254 | 24.0613 | 39.8107 | AID504937 |
| GLS protein | Homo sapiens (human) | Potency | 10.0000 | 0.3548 | 7.9355 | 39.8107 | AID624170 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 36.3799 | 0.0007 | 14.5928 | 83.7951 | AID1259369; AID1259392 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 2.8184 | 0.7079 | 12.1943 | 39.8107 | AID720542 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 72.7742 | 0.0030 | 41.6115 | 22,387.1992 | AID1159552; AID1159555 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 0.8412 | 0.3758 | 27.4851 | 61.6524 | AID743220 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 2.6365 | 0.0355 | 20.9770 | 89.1251 | AID504332 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 0.0018 | 15.6638 | 39.8107 | AID894 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 89.1251 | 0.0060 | 26.1688 | 89.1251 | AID540317 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 33.4915 | 0.0003 | 23.4451 | 159.6830 | AID743065 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 19.9526 | 0.0224 | 21.0102 | 89.1251 | AID485314 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 0.1000 | 28.9256 | 213.3130 | AID588591 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 28.1838 | 0.0501 | 27.0736 | 89.1251 | AID588590 |
| geminin | Homo sapiens (human) | Potency | 1.2589 | 0.0046 | 11.3741 | 33.4983 | AID624297 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 22.3872 | 0.0316 | 22.3146 | 100.0000 | AID588579 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 17.7828 | 0.0096 | 10.5250 | 35.4813 | AID1479145 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 9.5283 | 0.0601 | 10.7453 | 37.9330 | AID485367 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 83.0000 | 0.0000 | 1.3726 | 10.0000 | AID1803130 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 83.0000 | 0.0000 | 0.7236 | 9.9200 | AID1803130 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 (µMol) | 100.0000 | 0.1700 | 4.5590 | 10.0000 | AID1423480 |
| Solute carrier family 15 member 1 | Homo sapiens (human) | IC50 (µMol) | 10,000.0000 | 0.1800 | 0.1900 | 0.2000 | AID679007 |
| Solute carrier family 15 member 1 | Homo sapiens (human) | Ki | 14,750.0000 | 0.1800 | 3.3933 | 9.8000 | AID238858; AID681115 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 (µMol) | 100.0000 | 0.1700 | 4.5590 | 10.0000 | AID1423480 |
| Solute carrier family 15 member 2 | Homo sapiens (human) | Ki | 1,294.1250 | 0.7943 | 4.2210 | 8.0000 | AID612540 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 (µMol) | 100.0000 | 0.0600 | 3.9631 | 9.7000 | AID1423472 |
| 60 kDa chaperonin | Escherichia coli | IC50 (µMol) | 100.0000 | 0.0390 | 3.5552 | 9.8000 | AID1423469; AID1423470 |
| Solute carrier family 15 member 2 | Rattus norvegicus (Norway rat) | Ki | 984.5000 | 3.0000 | 6.4778 | 8.5000 | AID681114; AID681347 |
| 10 kDa chaperonin | Escherichia coli | IC50 (µMol) | 100.0000 | 0.0390 | 3.5552 | 9.8000 | AID1423469; AID1423470 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Chain A, Mutant Al2 6e7p9g | Mus musculus (house mouse) | Kd | 1.5400 | 1.5400 | 1.5400 | 1.5400 | AID977611 |
| Angiopoietin-1 receptor | Homo sapiens (human) | Kd | 82.0000 | 0.0031 | 1.3464 | 6.7000 | AID653693 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Beta-lactamase | Citrobacter freundii | Km | 38.0000 | 5.0000 | 7.0000 | 9.0000 | AID405084 |
| Beta-lactamase | Acinetobacter baumannii | Km | 9.0000 | 3.0000 | 5.6667 | 9.0000 | AID567279 |
| Beta-lactamase | Burkholderia cenocepacia | Km | 100.0000 | 10.0000 | 10.0000 | 10.0000 | AID541022 |
| Metallo-beta-lactamase type 2 | Klebsiella pneumoniae | Km | 22.0000 | 8.0000 | 9.3333 | 10.0000 | AID563972 |
| Metallo-beta-lactamase VIM-11 | Pseudomonas aeruginosa | Km | 109.0000 | 4.5000 | 7.0000 | 9.4000 | AID520385 |
| Metallo-beta-lactamase VIM-2 | Pseudomonas aeruginosa | Km | 136.0000 | 5.5000 | 7.8750 | 9.9000 | AID520386 |
| Beta-lactamase | Aeromonas allosaccharophila | Km | 20.0000 | 1.5000 | 6.3000 | 10.0000 | AID584846 |
| Metallo-beta-lactamase | Stutzerimonas stutzeri | Km | 110.0000 | 3.5000 | 4.7500 | 6.0000 | AID518728 |
| Beta-lactamase | Acinetobacter baumannii | Km | 7.0000 | 6.0000 | 7.6667 | 10.0000 | AID567280 |
| Beta-lactamase | Acinetobacter pittii | Km | 0.1200 | 0.0200 | 2.1814 | 6.7300 | AID555223 |
| Beta-lactamase | Acinetobacter pittii | Km | 1.0300 | 0.1800 | 1.3683 | 3.8500 | AID555225 |
| Beta-lactamase | Acinetobacter pittii | Km | 1.5000 | 0.1300 | 1.5250 | 4.5400 | AID555227 |
| Efflux transporter | Salmonella enterica subsp. enterica serovar Newport | Km | 0.1000 | 0.1000 | 3.8750 | 10.0000 | AID540966 |
| Beta-lactamase | Klebsiella pneumoniae | Km | 0.1000 | 0.1000 | 3.0250 | 7.3000 | AID540967 |
| Metallo-beta-lactamase | Escherichia coli | Km | 106.2500 | 2.0000 | 6.8571 | 10.0000 | AID583083; AID583084; AID583085; AID583094 |
| Beta-lactamase | Klebsiella pneumoniae | Km | 150.0000 | 1.0000 | 4.4500 | 7.9000 | AID1320835 |
| Carbapenem-hydrolyzing beta-lactamase KPC | Klebsiella pneumoniae | Km | 130.0000 | 1.6000 | 3.8000 | 6.0000 | AID374025 |
| Beta-lactamase class B VIM-2 | Pseudomonas aeruginosa | Km | 90.0000 | 2.0000 | 6.6500 | 9.4000 | AID531315 |
| Beta-lactamase VIM-1 | Pseudomonas aeruginosa | Km | 1,737.0000 | 4.0000 | 4.0000 | 4.0000 | AID530340 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1436942 | Antibacterial activity against Bacillus subtilis ATCC 23857 after 12 hrs | 2017 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 27, Issue:4 | Quinolidene based monocarbonyl curcumin analogues as promising antimycobacterial agents: Synthesis and molecular docking study. |
| AID324305 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoBR mutant assessed as cell count in stationary phase at 100 ug/ml after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID529625 | Antibacterial activity against Beta-lactamase negative Haemophilus influenzae harboring fst1 mutant gene assessed as susceptible isolates after 20 to 24 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID1105400 | Antibacterial activity against Klebsiella pneumoniae MTCC 7028 assessed as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID1114821 | Antibacterial activity against Pseudomonas aeruginosa ATCC 43288 after 18 to 24 hr by double microdilution method | 2013 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, Aug, Volume: 22, Issue:8 | |
| AID1908125 | Antibacterial activity against vancomycin-resistant Enterococcus faecium clinical isolate assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID324997 | Antibacterial activity against Haemophilus segnis ATCC 33393 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID510156 | Antimicrobial activity against Staphylococcus aureus ATCC 35218 by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID278563 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium longum ATCC 15707 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID600680 | Bactericidal activity against Bacillus cereus clinical isolate after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID1593643 | Antibacterial activity against Escherichia coli NBRC 3301 after 17 hrs by broth microdilution method | 2019 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 29, Issue:11 | Synthesis, antibacterial and cytotoxic evaluation of flavipucine and its derivatives. |
| AID289238 | Antimicrobial activity against Bacillus subtilis | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18 | Utility of 6-amino-2-thiouracil as a precursor for the synthesis of bioactive pyrimidine derivatives. |
| AID1265693 | Antibiofilm activity against Paracoccus sp. 4M6 assessed as microbial adhesion at 200 uM after 15 hrs by Syto61 based-fluorescence analysis relative to control | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Click-based synthesis of bromotyrosine alkaloid analogs as potential anti-biofilm leads for SAR studies. |
| AID1424742 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 after 24 hrs by two-fold serial dilution method | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | New pyrazolopyridine analogs: Synthesis, antimicrobial, antiquorum-sensing and antitumor screening. |
| AID324992 | Antibacterial activity against Haemophilus haemolyticus MSC07286 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID562595 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecalis clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID382704 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 at 572.4 uM by disc-diffusion method | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives. |
| AID533130 | Antimicrobial activity against Bacteroides distasonis assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID572231 | Antibacterial activity against Ruminococcus obeum by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID574178 | Antibacterial activity against Escherichia coli MG1655 grown as biofilms assessed as inhibition of bacterial biofilms formation at 5 to 500 ug/ml | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID442402 | Antimicrobial activity against Staphylococcus aureus at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1286503 | Ratio of MBC for methicillin-sensitive Staphylococcus aureus ATCC 49775 to MIC90 for methicillin-sensitive Staphylococcus aureus ATCC 49775 | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID471913 | Antibacterial activity against Pseudomonas putida MTCC 1072 at 128 ug/ml after 16 hrs by disc diffusion method | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | A facile one-pot green synthesis and antibacterial activity of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes. |
| AID496591 | Antimicrobial activity against Escherichia coli DH10B harboring beta lactamase KPC-2 by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase. |
| AID585450 | Antimicrobial activity against ampD, ampDh2, ampDh3 and ampG deficient Pseudomonas aeruginosa PAO1 harboring pUCP24 conferring resistance to gentamycin after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1265694 | Antibiofilm activity against Paracoccus sp. 4M6 assessed as reduction in adhesion after 15 hrs by Syto61 based-fluorescence analysis relative to control | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Click-based synthesis of bromotyrosine alkaloid analogs as potential anti-biofilm leads for SAR studies. |
| AID727797 | Antimicrobial activity against Escherichia coli DH10B expressing wild type Beta-lactamase SHV-1 by CLSI agar dilution method | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3 | Design and exploration of novel boronic acid inhibitors reveals important interactions with a clavulanic acid-resistant sulfhydryl-variable (SHV) β-lactamase. |
| AID548943 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after18 to 20 hrs by broth dilution method | 2010 | European journal of medicinal chemistry, Dec, Volume: 45, Issue:12 | Synthesis and antimicrobial evaluation of some fused heterocyclic [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives. |
| AID318719 | Antimicrobial activity against Candida tropicalis ATCC 1369 upto 100 ug/ml by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID533420 | Antimicrobial activity against Micromonas micros assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID567457 | Antimicrobial activity against Salmonella enterica serovar Typhi isolate 080049Ty by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Plasmid-mediated resistance to cephalosporins in Salmonella enterica serovar Typhi. |
| AID1496308 | Antibacterial activity against vancomycin-susceptible Enterococcus faecalis ATCC 29212 after 24 hrs | 2018 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 28, Issue:12 | In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci. |
| AID530219 | Antimicrobial activity against Mycobacterium bovis BCG ML1053 carrying transposon IS1096::Km inserted at +271bp of bcg2326c gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID563967 | Antibacterial activity against Escherichia coli TOP10 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. |
| AID1769952 | Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC 62202 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID583090 | Activity of Escherichia coli XL1-Blue IMP-1 W64A mutant beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID585846 | Antimicrobial activity against Pseudomonas aeruginosa isolate 3 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID534947 | Antimicrobial activity against Fusobacterium varium by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID542735 | Antimicrobial activity against Klebsiella pneumoniae D10 expressing aac(6')-Ib-cr, qnrB4, CTX-M-1G and DHA-1 genes by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID1491153 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate shhs-A1 by CLSI method | 2017 | Journal of natural products, 05-26, Volume: 80, Issue:5 | Antimicrobial Spirotetronate Metabolites from Marine-Derived Micromonospora harpali SCSIO GJ089. |
| AID557458 | Antimicrobial activity in Prevotella nigrescens by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID289239 | Antimicrobial activity against Staphylococcus aureus | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18 | Utility of 6-amino-2-thiouracil as a precursor for the synthesis of bioactive pyrimidine derivatives. |
| AID373677 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 after 24 hrs by broth microdilution method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID1225289 | Antibacterial activity against Kocuria rhizophila NBRC 12708 incubated for 12 hrs at 37 degC | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Pentacyclic antibiotics from a tidal mud flat-derived actinomycete. |
| AID562593 | Antimicrobial activity against Enterococcus faecalis expressing VanA gene clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID532029 | Antimicrobial activity against Escherichia coli TOP10F' transformant harboring beta-lactamase CTX-M-78 by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. |
| AID544284 | Antimicrobial activity against Enterococcus faecalis NKH14 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID584328 | Antibacterial activity against gshB deficient Escherichia coli JW2914-1 | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Interplay between drug efflux and antioxidants in Escherichia coli resistance to antibiotics. |
| AID546953 | Antibacterial activity against Shigella flexneri assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1286500 | Bactericidal activity against methicillin-sensitive Staphylococcus aureus ATCC 29213 after 24 and 48 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID1164946 | Antimicrobial activity against Klebsiella pneumoniae ATCC 33495 at >200 ug/ml by microbroth dilution method | 2014 | Journal of medicinal chemistry, Oct-23, Volume: 57, Issue:20 | Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives. |
| AID266675 | Antibacterial activity against Klebsiella pneumoniae | 2006 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 16, Issue:14 | Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives. |
| AID372548 | Antibacterial activity against genetically beta-lactamase-negative ampicillin-resistant Haemophilus influenzae type b with an amino acid substitution in variable mutated locus Asn-526 or Arg-517 of ftsI gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID534717 | Antimicrobial activity against Parabacteroides distasonis by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID565019 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1546173 | Antimicrobial activity against Klebsiella pneumoniae ATCC 700603 assessed as zone of inhibition at 100 ug/ml after 24 hrs by disc diffusion method | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID325487 | Antimicrobial activity against vancomycin B-resistant Enterococcus faecalis TX2484 isolate by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Time-kill and synergism studies of ceftobiprole against Enterococcus faecalis, including beta-lactamase-producing and vancomycin-resistant isolates. |
| AID1322099 | Antimicrobial activity against Bacillus subtilis ATCC 6633 after 24 hrs by broth microdilution assay | 2016 | Bioorganic & medicinal chemistry, 11-01, Volume: 24, Issue:21 | Synthesis, characterization, and evaluation of (E)-methyl 2-((2-oxonaphthalen-1(2H)-ylidene)methylamino)acetate as a biological agent and an anion sensor. |
| AID547170 | Antibacterial activity against Plesiomonas shigelloides by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1287090 | Antimicrobial activity against antibiotic resistant Candida albicans clinical isolate 08030102 after 16 hrs by broth dilution method | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis. |
| AID671477 | Antibacterial activity against Staphylococcus saprophyticus ATCC 15305 after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Aug-01, Volume: 20, Issue:15 | Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. |
| AID534975 | Antimicrobial activity against Clostridium hathewayi by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID74713 | Inhibition of gram negative (resistant) growth. | 1989 | Journal of medicinal chemistry, Jun, Volume: 32, Issue:6 | Synthesis and antimicrobial properties of substituted beta-aminoxypropionyl penicillins and cephalosporins. |
| AID276382 | Antibacterial activity against Staphylococcus aureus by broth microdilution technique | 2006 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 16, Issue:22 | Naphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: synthesis and biological evaluation as potential antibacterial and antifungal agents. |
| AID634990 | Antibacterial activity against drug-sensitive Bacillus cereus ATCC 10876 by broth microdilution method | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1 | Studies on the synthesis and antibacterial activity of 3,6-disubstituted 1,2,4-triazolo[3,4-b]1,3,4-thiadiazoles. |
| AID547782 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237I mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID565439 | Antimicrobial activity against Streptococcus intermedius SI006 biofilm harboring luxS mutant gene assessed as biofilm bacterial count at 0.04 ug/ml (Rvb =310.8 +/- 17.10 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID572241 | Antibacterial activity against Peptoniphilus asaccharolyticus by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1546089 | Antimicrobial activity against Staphylococcus aureus | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID1721979 | Bactericidal activity against Erwinia carotovora | 2020 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 30, Issue:17 | New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. |
| AID1767676 | Antibacterial activity against Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028 assessed as inhibition of bacterial growth incubated for 24 hrs by microdilution assay | 2021 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 47 | Antimicrobial, modulatory, and antibiofilm activity of tt-farnesol on bacterial and fungal strains of importance to human health. |
| AID546936 | Antibacterial activity against Salmonella enterica serovar Choleraesuis by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID535463 | Antimicrobial activity against Propionibacterium propionicum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1399501 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID1185236 | Antimicrobial activity against Bacillis subtilis RCMB 010067 assessed as inhibition zone at 5 mg/ml after 24 hrs | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety. |
| AID655627 | Antibacterial activity against Pseudomonas aeruginosa ATCC 15499 at 20 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID585865 | Antimicrobial activity against Pseudomonas aeruginosa isolate 13 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID360050 | Antimicrobial activity against Enterococcus faecium M512 by agar dilution method after 48 hrs | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID573370 | Antibacterial activity against ceftazidime-susceptible Serratia marcescens by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID324162 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid PhoU after 16 hrs by serial dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID572055 | Antibacterial activity against Bifidobacterium infantis by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1496311 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis 725B after 24 hrs | 2018 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 28, Issue:12 | In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci. |
| AID352573 | Antimicrobial activity against Escherichia coli ATCC 25922 at 10 ug after 18 hrs by agar-well diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Synthesis of some new 1,2,4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities. |
| AID573391 | Antibacterial activity against ceftazidime-susceptible Providencia sp. by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID467608 | Antibacterial activity against Bacillus thuringiensis by twofold serial broth dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new thiazole and thiophene derivatives. |
| AID444053 | Renal clearance in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID528531 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B60 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID442430 | Antimicrobial activity against Salmonella Typhimurium after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID584847 | Ratio of Kcat to Km for Aeromonas allosaccharophila AL-1 beta-lactamase PER6 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | PER-6, an extended-spectrum beta-lactamase from Aeromonas allosaccharophila. |
| AID529897 | Antimicrobial activity against Leptospira interrogans serovar Pyrogenes isolate 5 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID1314114 | Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr in presence of sodium pyrophosphate by fluorescence polarization assay | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16 | Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents. |
| AID535360 | Antimicrobial activity against Haemophilus influenzae clinical isolates by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Antimicrobial resistance among respiratory pathogens in Spain: latest data and changes over 11 years (1996-1997 to 2006-2007). |
| AID546623 | Ratio of MIC for Escherichia coli harboring beta-lactamase VIM-2 to MIC for Escherichia coli harboring beta-lactamase VIM-18 | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). |
| AID510164 | Antimicrobial activity against extended spectrum beta lactamase expressing Escherichia coli by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID535443 | Antimicrobial activity against Lactobacillus acidophilus by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID547182 | Antibacterial activity against Vibrio fluvialis by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID530220 | Antimicrobial activity against Mycobacterium bovis BCG ML1029 carrying transposon IS1096::Km inserted at +524bp of bcg2734c gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID572030 | Antibacterial activity against Clostridium ramosum by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID520873 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus saprophyticus isolate TSU69 isolated from genitourinary tracts of acute cystitis patient after 24 hrs at 35 degC by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Methicillin-resistant Staphylococcus saprophyticus isolates carrying staphylococcal cassette chromosome mec have emerged in urogenital tract infections. |
| AID633494 | Antifungal activity against Candida albicans ATCC 10231 after 24 to 72 hrs by two fold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial activity of brominated resorcinol dimers. |
| AID546949 | Antibacterial activity against Shigella sonnei assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID519012 | Activity of Beta-lactamase TEM-10 | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | E240V substitution increases catalytic efficiency toward ceftazidime in a new natural TEM-type extended-spectrum beta-lactamase, TEM-149, from Enterobacter aerogenes and Serratia marcescens clinical isolates. |
| AID583086 | Ratio of Kcat to Km for Escherichia coli XL1-Blue IMP-1 W64A mutant beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID585442 | Antimicrobial activity against ampGh1 deficient Pseudomonas aeruginosa PAK after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID465613 | Antibacterial activity against Escherichia coli ATCC 25922 | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Discorhabdins from the Korean marine sponge Sceptrella sp. |
| AID1105383 | Antibacterial activity against Erwinia chrysanthemi ITCC B-40 assessed as as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID555211 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 109 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID770908 | Antibacterial activity against Pseudomonas aeruginosa IFO 3448 assessed as growth inhibition at 100 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID1265193 | Antibacterial activity against Escherichia coli ATCC 8739 after 24 hrs by microtiter plate method | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes. |
| AID278231 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21 tolC::Kan | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID278558 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium animalis ATCC 27536 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID529585 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-10 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID567764 | Antimicrobial activity against Bacillus cereus ATCC 10876 after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID465615 | Antibacterial activity against Salmonella Typhimurium ATCC 14028 | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Discorhabdins from the Korean marine sponge Sceptrella sp. |
| AID535237 | Antimicrobial activity against Bifidobacterium infantis by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID585833 | Antimicrobial activity against ampG deficient Pseudomonas aeruginosa PAK harboring pZY0901 conferring resistance to gentamycin after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID537666 | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 18 hrs by agar-well diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Cyclization of some carbothioamide derivatives containing antipyrine and triazole moieties and investigation of their antimicrobial activities. |
| AID534385 | Antibacterial activity against Escherichia coli K-12 W1895 by microdilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate. |
| AID572247 | Antibacterial activity against Parabacteroides distasonis by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID535197 | Antimicrobial activity against Clostridium paraputrificum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID640579 | Antibacterial activity against Escherichia coli ATCC 35270 | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2 | Bioactive lipids from the sponge Spirastrella abata. |
| AID1334267 | Antibacterial activity against Pseudomonas aeruginosa | 2017 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 27, Issue:2 | New bithiazolyl hydrazones: Novel synthesis, characterization and antitubercular evaluation. |
| AID534979 | Antimicrobial activity against Clostridium orbiscindens by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID554989 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 60 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID557394 | Antibacterial activity against Beta-lactamase-negative Neisseria meningitidis assessed as percent resistant isolates by Etest method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antibiotic susceptibility and characteristics of Neisseria meningitidis isolates from the African meningitis belt, 2000 to 2006: phenotypic and genotypic perspectives. |
| AID555240 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 52 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1176778 | Antimicrobial activity against Saccharomyces cerevisiae BY4741 after 24 hrs by broth microdilution method | 2015 | Journal of natural products, Jan-23, Volume: 78, Issue:1 | Structure and antimicrobial activity of phloroglucinol derivatives from Achyrocline satureioides. |
| AID1323298 | Antibacterial activity against Staphylococcus aureus ATCC 6538p after 24 hrs by serial two fold dilution method | 2016 | Journal of natural products, 07-22, Volume: 79, Issue:7 | Actinomadurol, an Antibacterial Norditerpenoid from a Rare Actinomycete, Actinomadura sp. KC 191. |
| AID340887 | Antimicrobial activity against Escherichia coli JM83 harboring pACYC184-ATEM by serial dilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Cytoplasmic-membrane anchoring of a class A beta-lactamase and its capacity in manifesting antibiotic resistance. |
| AID447438 | Antibacterial activity against Escherichia coli ATCC 8739 at 100 ug/ml after 24 hrs by agar cup plate method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and antibacterial activity of 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-pyrazol-4-yl]-5-(substituted-phenyl)-[1,3,4]oxadiazoles. |
| AID1695860 | Antibacterial activity against Micrococcus Luteus ATCC 398 incubated for 24 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID535362 | Antimicrobial activity against Haemophilus influenzae clinical isolates assessed as susceptible isolates by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Antimicrobial resistance among respiratory pathogens in Spain: latest data and changes over 11 years (1996-1997 to 2006-2007). |
| AID1265197 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by microtiter plate method | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes. |
| AID572223 | Antibacterial activity against Catenibacterium mitsuokai by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID255561 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 32.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID334236 | Antimicrobial activity against Epidermophyton floccosum after 10 days by microdilution technique | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4 | Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline. |
| AID463405 | Antimicrobial activity against Escherichia coli at 1000 ug after 24 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines. |
| AID523268 | Activity at Escherichia coli isolate HN1157 AcrAB-TolC efflux transporter | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Kinetic parameters of efflux of penicillins by the multidrug efflux transporter AcrAB-TolC of Escherichia coli. |
| AID1364565 | Antimicrobial activity against Escherichia coli W3110 incubated for 20 hrs by CLSI protocol based method | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | Identification of Pyridinium with Three Indole Moieties as an Antimicrobial Agent. |
| AID519655 | Antimicrobial activity against Escherichia coli GM2995 harboring plasmid pCC1 carrying beta-lactamase CTX-M-3 Ser167 mutant gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID555225 | Activity of Acinetobacter genomosp. 3 isolate 103 ADC-16 | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID534716 | Antimicrobial activity against Bacteroides fragilis by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID372562 | Antibacterial activity against genetically beta-lactamase-positive amoxicillin-clavulanate-resistant Haemophilus influenzae type b with an amino acid substitution in variable mutated locus Asn-526 or Arg-517 of ftsI gene assessed as resistance rate by bro | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID382816 | Antimicrobial activity against Escherichia coli ATCC 25922 | 2008 | European journal of medicinal chemistry, Mar, Volume: 43, Issue:3 | Synthesis and biological evaluation of some thiazolyl and thiadiazolyl derivatives of 1H-pyrazole as anti-inflammatory antimicrobial agents. |
| AID558815 | Antimicrobial activity against Pseudomonas aeruginosa assessed as percent susceptible isolates by CLSI method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007. |
| AID584482 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN12 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID278253 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS3 gyrA+ with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID547769 | Antimicrobial activity against Escherichia coli DH10B harboring plasmid pBC SK(+) carrying wild type beta-lactamase KPC-2 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID425596 | Antibacterial activity against extracellular Escherichia coli isolate HM605 isolated from colonic mucosal biopsies of patient with Crohn's disease at 0.01 to 10 ug/ml after 3 hrs | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID565623 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.06 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =793.3 +/- 42.40 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID1870152 | Antibacterial activity against wild type Staphylococcus aureus 4738/B assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID400379 | Antibacterial activity against Klebsiella pneumoniae at 200 ug/100uL after 24 hrs by agar well diffusion method | 1998 | Journal of natural products, Feb, Volume: 61, Issue:2 | Antibacterial steroidal alkaloids from Sarcococca saligna. |
| AID530517 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype V isolate 3386-05 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID1185774 | Antimicrobial activity against Candida albicans ATCC 10231 assessed as inhibition zone after 24 hrs by agar well diffusion method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Discovery of diethyl 2,5-diaminothiophene-3,4-dicarboxylate derivatives as potent anticancer and antimicrobial agents and screening of anti-diabetic activity: synthesis and in vitro biological evaluation. Part 1. |
| AID514126 | Antibacterial activity against methicillin-resistant Staphylococcus aureus Mu50 assessed as growth inhibition at 1 mg/ml after 16 to 20 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays. |
| AID1887298 | Antibacterial activity against Staphylococcus epidermidis ATCC 51625 assessed as inhibition of bacterial growth incubated for 24 hrs by optical density based analysis | 2022 | Journal of natural products, 09-23, Volume: 85, Issue:9 | Total Syntheses and Antibacterial Evaluations of Neocyclomorusin and Related Flavones. |
| AID535644 | Antimicrobial activity against Group B streptococcus serotype Ib N2 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID752006 | Antibacterial activity against Staphylococcus aureus NCIM 2901 by broth dilution method | 2013 | Bioorganic & medicinal chemistry letters, May-01, Volume: 23, Issue:9 | Green synthesis of tetrahydropyrimidine analogues and evaluation of their antimicrobial activity. |
| AID547763 | Antimicrobial activity against Klebsiella pneumoniae 1534 expressing beta-lactamase KPC-2 by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID557724 | Antimicrobial activity in Fusobacterium varium by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID558804 | Antimicrobial activity against extended spectrum beta-lactamase-deficient Klebsiella oxytoca assessed as percent susceptible isolates by CLSI method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007. |
| AID559900 | Antimicrobial activity against Klebsiella pneumoniae 278 harboring beta-lactamase OXY-1 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | First detection of plasmid-encoded blaOXY beta-lactamase. |
| AID287379 | Antibacterial activity against Pseudomonas aeruginosa after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID655703 | Antibacterial activity against Pseudomonas aeruginosa ATCC 15499 after 24 hrs by serial broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID1694050 | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as diameter of zone inhibition at 5 mg/ml incubated for 24 hrs by agar plate diffusion method | 2021 | Bioorganic & medicinal chemistry, 02-01, Volume: 31 | Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study. |
| AID585443 | Antimicrobial activity against ampG, ampGh1 deficient Pseudomonas aeruginosa PAK after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1399267 | Antimicrobial activity against Stenotrophomonas maltophilia ATCC 700475 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID278561 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium breve ATCC 15700 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID383174 | Antimicrobial activity against Bacillus subtilis ATCC 6633 | 2008 | Journal of natural products, Apr, Volume: 71, Issue:4 | Sesterterpenoids from the sponge Sarcotragus sp. |
| AID1877440 | Antibacterial activity against Legionella pneumophila subsp. pneumophila | 2022 | Bioorganic & medicinal chemistry letters, 01-01, Volume: 55 | New bis- and tetrakis-1,2,3-triazole derivatives: Synthesis, DNA cleavage, molecular docking, antimicrobial, antioxidant activity and acid dissociation constants. |
| AID518729 | Ratio of Kcat to Km for Pseudomonas stutzeri beta-lactamase DIM-1by UV-spectrophotometry | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Characterization of DIM-1, an integron-encoded metallo-beta-lactamase from a Pseudomonas stutzeri clinical isolate in the Netherlands. |
| AID657435 | Antibacterial activity against penicillin-resistant Streptococcus pneumoniae after 16 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9 | Preparation, antibacterial evaluation and preliminary structure-activity relationship (SAR) study of benzothiazol- and benzoxazol-2-amine derivatives. |
| AID531610 | Antimicrobial activity against Klebsiella pneumoniae Kp2792 expressing beta-lactamase SHV-56 by agar dilution method in presence of Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae. |
| AID585449 | Antimicrobial activity against Pseudomonas aeruginosa PAK after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID535744 | Antimicrobial activity against hospital-acquired Klebsiella pneumoniae obtained from patient with intra-abdominal infection assessed as susceptible isolates by EUCAST method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Incidence and antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae with extended-spectrum beta-lactamases in community- and hospital-associated intra-abdominal infections in Europe: results of the 2008 Study for Monitoring Antimicrob |
| AID595439 | Antibacterial activity against Micrococcus luteus IFO 12708 after 24 hrs by by twofold serial dilution method | 2011 | Journal of natural products, Apr-25, Volume: 74, Issue:4 | Scalarane sesterterpenes from the sponge Hyatella sp. |
| AID678544 | Antibacterial activity against Streptococcus pyogenes ATCC 19615 | 2012 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 22, Issue:18 | Design, solvent free synthesis, and antimicrobial evaluation of 1,4 dihydropyridines. |
| AID765557 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 after 18 to 24 hrs by double microdilution method | 2013 | European journal of medicinal chemistry, Sep, Volume: 67 | Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities. |
| AID1774191 | Antibacterial activity against Escherichia coli delta depA delta fiu assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID535449 | Antimicrobial activity against Lactobacillus jensenii by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID562525 | Antimicrobial activity against pbp5 gene-deficient vancomycin-, fusidic acid-, rifampin-resistant Enterococcus faecium D344SRF-C6 expressing hylEfm gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Cotransfer of antibiotic resistance genes and a hylEfm-containing virulence plasmid in Enterococcus faecium. |
| AID1180297 | Antimicrobial activity against Salmonella typhimurium NCIM-3471 after 20 hrs by two fold serial macrodilution technique | 2014 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15 | One pot three components microwave assisted and conventional synthesis of new 3-(4-chloro-2-hydroxyphenyl)-2-(substituted) thiazolidin-4-one as antimicrobial agents. |
| AID1535449 | Anti-biofilm activity against Paracoccus sp. 4M6 assessed as inhibition of bacterial adhesion incubated for 15 hrs at 20 degC by Syto 61 dye based fluorimetric assay | 2019 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 29, Issue:4 | Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds? |
| AID324217 | Antibacterial activity against Escherichia coli K12 containing PhoU mutant assessed as cell count in stationary phase at 100 ug/ml after 1 day | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID533366 | Antimicrobial activity against Bacteroides uniformis by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID1055949 | Antibacterial activity against Escherichia coli ATCC 25922 after 16 hrs | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID572259 | Antibacterial activity against Prevotella corporis by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID735973 | Antimicrobial activity against Botrytis fabae after 48 hrs by microdilution susceptibility test | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Synthesis and antimicrobial activity of some new benzo and naphthonitrile derivatives. |
| AID1411624 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hrs by microdilution method | |||
| AID533374 | Antimicrobial activity against Bacteroides eggerthii by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID555222 | Antibacterial activity against Escherichia coli DH5alpha carrying ampC gene of Acinetobacter genomosp. 3 isolate 195 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID547194 | Antibacterial activity against Campylobacter coli by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID577207 | Antimicrobial activity against Escherichia coli C600::H19B in stationary phase encoding Stx-1 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID634987 | Antibacterial activity against drug-sensitive Staphylococcus aureus ATCC 6538 by broth microdilution method | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1 | Studies on the synthesis and antibacterial activity of 3,6-disubstituted 1,2,4-triazolo[3,4-b]1,3,4-thiadiazoles. |
| AID534987 | Antimicrobial activity against Clostridium bartlettii by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID557410 | Antimicrobial activity in Bacteroides fragilis by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID583092 | Activity of Escherichia coli XL1-Blue VIM-2 A64W mutant beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID546934 | Antibacterial activity against Salmonella enterica serovar Paratyphi assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1185239 | Antimicrobial activity against Staphylococcus epidermidis RCMB 010024 assessed as absence of turbidity after 24 hrs | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety. |
| AID1399270 | Antimicrobial activity against Klebsiella pneumoniae isolate SJ 3 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID1721980 | Bactericidal activity against Xanthomonas campestris | 2020 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 30, Issue:17 | New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. |
| AID533360 | Antimicrobial activity against Bacteroides ovatus assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID546928 | Antibacterial activity against Salmonella enterica serovar Enteritidis assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID565608 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 planktonic cells assessed as bacterial count at 0.12 ug/ml (Rvb =771.7 +/- 35.14 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID1870159 | Antibacterial activity against wild type Staphylococcus aureus 78/CF assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID419828 | Antibacterial activity against Escherichia coli MTCC 722 at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Jun, Volume: 44, Issue:6 | Physicochemical and biological characterization of novel macrocycles derived from o-phthalaldehyde. |
| AID514129 | Antibacterial activity against Escherichia coli 1655 assessed as growth inhibition at 1 mg/ml after 16 to 20 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays. |
| AID585680 | Antimicrobial activity against ampG, ampGh1 deficient Pseudomonas aeruginosa PAK after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID556755 | Bactericidal activity against katG gene-deficient Escherichia coli K-12 3157 after 18 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID519642 | Antimicrobial activity against Escherichia coli EPI300 harboring pCC1 carrying beta-lactamase CTX-M-42 Pro167Thr mutant gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID318666 | Antibacterial activity against Mycoplasma pneumoniae FH Liu by broth microdilution method | 2008 | Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7 | Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens. |
| AID558331 | Antibacterial activity against bla gene-positive and nitrocefin reaction-positive beta-lactamase harboring Campylobacter jejuni isolate P338 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID1499654 | Antimicrobial activity against Streptococcus pneumoniae RCMB 010010 assessed as diameter of zone inhibition at 100 ug/ml after 24 hrs by agar well diffusion assay | 2017 | European journal of medicinal chemistry, Sep-29, Volume: 138 | Design, synthesis and 2D QSAR study of novel pyridine and quinolone hydrazone derivatives as potential antimicrobial and antitubercular agents. |
| AID1695929 | Antibacterial activity against Proteus vulgaris ATCC 3851 incubated for 24 hrs by broth dilution method | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID572268 | Antibacterial activity against Sutterella wadsworthensis by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID535227 | Antimicrobial activity against Atopobium minutum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1359448 | Antibacterial activity against Staphylococcus epidermidis NCIM 5270 after 12 hrs by serial dilution method | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Antibacterial and anti-TB tat-peptidomimetics with improved efficacy and half-life. |
| AID1693215 | Anti-infective activity against Staphylococcus aureus ATCC 6538 assessed as reduction in bacterial growth by microdilution method | 2021 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 32 | 2-Aryl-3-(6-trifluoromethoxy)benzo[d]thiazole-based thiazolidinone hybrids as potential anti-infective agents: Synthesis, biological evaluation and molecular docking studies. |
| AID1278999 | Antibacterial activity against Staphylococcus aureus incubated for 20 hrs by microbroth dilution method | 2016 | Bioorganic & medicinal chemistry, Mar-15, Volume: 24, Issue:6 | Synthesis of fluorinated carbazoles via C-H arylation catalyzed by Pd/Cu bimetal system and their antibacterial activities. |
| AID524969 | Antibacterial activity against vancomycin-susceptible Enterococcus faecium clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Comparative surveillance study of telavancin activity against recently collected gram-positive clinical isolates from across the United States. |
| AID543795 | Antimicrobial activity against Escherichia coli ATCC 25922 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID1055312 | Antibacterial activity against Bacillus cereus at 10 ug after 24 hrs by disk diffusion method | 2013 | European journal of medicinal chemistry, , Volume: 70 | Phosphorus-nitrogen compounds part 27. Syntheses, structural characterizations, antimicrobial and cytotoxic activities, and DNA interactions of new phosphazenes bearing secondary amino and pendant (4-fluorobenzyl)spiro groups. |
| AID303338 | Antibacterial activity against Escherichia coli K12 JM109 overexpressing beta-lactamase | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23 | Optimizing cell permeation of an antibiotic resistance inhibitor for improved efficacy. |
| AID547783 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237I mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID1185238 | Antimicrobial activity against Staphylococcus epidermidis RCMB 010024 assessed as inhibition zone at 5 mg/ml after 24 hrs | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety. |
| AID524824 | Antibacterial activity against erythromycin resistant Campylobacter sp. by agar plate dilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID572252 | Antibacterial activity against Bacteroides vulgatus by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID584764 | Antimicrobial activity against Acinetobacter lwoffii isolate C expressing beta-lactamase OXA-164 isolated from tracheal secretion of patient in presence of Sulbactam by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID1185234 | Antimicrobial activity against Streptococcus pneumoniae RCMB 010010 assessed as inhibition zone at 5 mg/ml after 24 hrs | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety. |
| AID559333 | Antimicrobial activity against Shigella flexneri harboring oxa-5-like gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID572227 | Antibacterial activity against Eggerthella lenta by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID555220 | Antibacterial activity against Escherichia coli DH5alpha carrying ampC gene of Acinetobacter genomosp. 3 isolate 103 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID557970 | Antimicrobial activity in Clostridium sp. by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1585669 | Antibacterial activity against methicillin-resistant Staphylococcus haemolyticus assessed as zone of inhibition at 10 ug/mL after 24 hrs by agar disc diffusion method | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug resistance of bacterial infections. |
| AID1596682 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID85797 | The compound was tested in vivo for antibacterial activity against Haemophilus influenza 351GR1 in mice after oral administration | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21 | Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens. |
| AID509325 | Antibacterial activity against ampicillin-resistant Pseudomonas putida MTCC 1072 at 128 mg/ml after 16 hrs by disk diffusion test | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antiviral and antibacterial agents. |
| AID548034 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237R mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID584771 | Antimicrobial activity against Acinetobacter lwoffii isolate J expressing beta-lactamase OXA-58 isolated from bedsore in presence of Sulbactam by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID759383 | Antibacterial activity against Staphylococcus aureus NCTC 7447 assessed as growth inhibition after 24 hrs by Kirby-Bauer disc diffusion method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis and biological evaluation of some novel thiazole compounds as potential anti-inflammatory agents. |
| AID572250 | Antibacterial activity against Bacteroides ovatus by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID534991 | Antimicrobial activity against Clostridium bifermentans by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID547997 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237C mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID587973 | Ratio of Kcat to Km for Escherichia coli beta-lactamase Toho-1 D240A mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID665056 | Antibacterial activity against Streptococcus pneumoniae MTCC 1936 after 24 hrs by micro-broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 22, Issue:11 | An efficient one-pot synthesis, structure, antimicrobial and antioxidant investigations of some novel quinolyldibenzo[b,e][1,4]diazepinones. |
| AID535207 | Antimicrobial activity against Clostridium sordellii by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID531600 | Antimicrobial activity against Escherichia coli JM109 harboring pE1 plasmid expressing beta-lactamase SHV-11 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae. |
| AID572230 | Antibacterial activity against Ruminococcus gnavus by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID425584 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM605 isolated from colonic mucosal biopsies of patient with Crohn's disease in mouse J774A1 cells assessed as intracellular killing of bacteria at 3.2 ug/ml after 3 h | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID573364 | Antibacterial activity against ceftazidime-susceptible Morganella morganii by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1577950 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 under iron-sufficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID585426 | Antimicrobial activity against oqxAB positive Escherichia coli C600 X1B1-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID572235 | Antibacterial activity against Ruminococcus lactaris by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1265200 | Bactericidal activity against Klebsiella pneumoniae ATCC 43816 after 24 hrs | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes. |
| AID324980 | Antibacterial activity against Haemophilus influenzae MSC07237 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID534389 | Antibacterial activity against Escherichia coli JM109 harboring recombinant pKHM-1 by microdilution method in presence of Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate. |
| AID1114115 | Antibacterial activity against Bacillus cereus ATCC 10876 assessed as growth inhibition by broth microdilution method | 2013 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, May, Volume: 22, Issue:5 | Microbiologically active Mannich bases derived from 1,2,4-triazoles. The effect of C-5 substituent on antibacterial activity. |
| AID565745 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecium clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID534933 | Antimicrobial activity against Desulfovibrio fairfieldensis by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID572243 | Antibacterial activity against Peptostreptococcus micros by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1755803 | Antibacterial activity against Staphylococcus aureus ATCC 6538P incubated for 24 hrs by broth microdilution method | 2021 | European journal of medicinal chemistry, Jan-15, Volume: 210 | Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective. |
| AID534394 | Activity of Beta-lactamase KHM-1 in Escherichia coli JM109 harboring recombinant pKHM-1 assessed as compound hydrolysis by UV-visible spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate. |
| AID1653047 | Antibacterial activity against Staphylococcus aureus | 2019 | European journal of medicinal chemistry, Feb-15, Volume: 164 | Isatin derivatives and their anti-bacterial activities. |
| AID534977 | Antimicrobial activity against Clostridium innocuum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID567760 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID584767 | Antimicrobial activity against Acinetobacter lwoffii isolate F expressing beta-lactamase OXA-164 isolated from tracheostoma of patient in presence of Sulbactam by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID572051 | Antibacterial activity against Bifidobacterium adolescentis by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID557736 | Antimicrobial activity in Peptostreptococcus anaerobius by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID530231 | Antimicrobial activity against Mycobacterium bovis BCG ML1042 carrying transposon IS1096::Km inserted at -509bp of bcg2123c/pe22 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID372558 | Antibacterial activity against genetically beta-lactamase-negative ampicillin-resistant Haemophilus influenzae type b with bla gene but without an amino acid substitution in ftsI gene assessed as susceptibility rate by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID572262 | Antibacterial activity against Prevotella intermedia by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1916833 | Antibacterial activity against Bacillus subtilis NCIM 2079 assessed as reduction in bacterial growth incubated for 8 hrs by absorbance based assay | 2022 | European journal of medicinal chemistry, Aug-05, Volume: 238 | Recent contribution of medicinally active 2-aminothiophenes: A privileged scaffold for drug discovery. |
| AID324233 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 assessed as cell count in stationary phase at 100 ug/ml after 1 week | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1225333 | Antimicrobial activity against Escherichia coli incubated for 24 hrs | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Alkaloidal metabolites from a marine-derived Aspergillus sp. fungus. |
| AID562521 | Antimicrobial activity against erythromycin-, streptomycin-, vancomycin-, gentamicin-resistant Enterococcus faecium TX1330RF-B1 conjugant expressing hylEfm gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Cotransfer of antibiotic resistance genes and a hylEfm-containing virulence plasmid in Enterococcus faecium. |
| AID386970 | Antimicrobial activity Botrytis fabae at 25 ug/mL after 48 hrs by agar diffusion technique | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10 | Synthesis and antimicrobial activity of some new heterocycles incorporating antipyrine moiety. |
| AID529903 | Antimicrobial activity against Leptospira kirschneri serovar Grippotyphosa isolate 13 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID572057 | Antibacterial activity against Bifidobacterium pseudolongum by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1870144 | Antibacterial activity against wild type Staphylococcus aureus 4883/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID535427 | Antimicrobial activity against Eubacterium alactolyticum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID584485 | Antibacterial activity against mecA-negative Staphylococcus lentus ATCC 29070T by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID1592960 | Antibacterial activity against multi-drug resistant Klebsiella pneumoniae NMI 3081/09 assessed as reduction in microbial growth incubated for 20 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. |
| AID524826 | Antibacterial activity against erythromycin resistant Campylobacter sp. assessed as resistance breakpoint by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID671470 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Aug-01, Volume: 20, Issue:15 | Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. |
| AID671476 | Antibacterial activity against Staphylococcus intermedius ATCC 29663 after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Aug-01, Volume: 20, Issue:15 | Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. |
| AID555449 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 243 by Etest method in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1668057 | Inhibition of DHPS in Klebsiella pneumoniae assessed as antibacterial activity by measuring inhibition zone at 5 mg/mL incubated for 24 hrs by disk diffusion method | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9 | New acrylamide-sulfisoxazole conjugates as dihydropteroate synthase inhibitors. |
| AID324234 | Antibacterial activity against Escherichia coli K12 containing PhoU mutant assessed as cell count in log phase at 100 ug/ml after 1 week | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1226731 | Antimicrobial activity against Staphylococcus aureus incubated at 37 degC overnight for 18 hrs | 2015 | ACS medicinal chemistry letters, Apr-09, Volume: 6, Issue:4 | Membrane-Targeting DCAP Analogues with Broad-Spectrum Antibiotic Activity against Pathogenic Bacteria. |
| AID1561472 | Antibacterial activity against wild type Escherichia coli TG1 in Mueller-Hinton broth by CLSI protocol based method | |||
| AID1462723 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 1688 | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20 | Benzothiazole analogues: Synthesis, characterization, MO calculations with PM6 and DFT, in silico studies and in vitro antimalarial as DHFR inhibitors and antimicrobial activities. |
| AID1496320 | Cytotoxicity against human THP1 cells after 24 hrs by LDH release assay | 2018 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 28, Issue:12 | In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci. |
| AID577204 | Antimicrobial activity against Escherichia coli O157:H7 PT-40 in stationary phase encoding Stx-2 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID535235 | Antimicrobial activity against Bifidobacterium dentium by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1329754 | Antibacterial activity against Streptococcus mitis NCIMB 13770 after 24 hrs by broth microdilution method | |||
| AID634989 | Antibacterial activity against drug-sensitive Bacillus subtilis ATCC 6633 by broth microdilution method | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1 | Studies on the synthesis and antibacterial activity of 3,6-disubstituted 1,2,4-triazolo[3,4-b]1,3,4-thiadiazoles. |
| AID1466813 | Antibacterial activity against Staphylococcus aureus ATCC 6538 assessed as diameter of inhibition zone after 24 hrs by agar well diffusion method | 2017 | Bioorganic & medicinal chemistry letters, 06-15, Volume: 27, Issue:12 | Synthesis and in vitro biological evaluation of novel coumarin derivatives containing isoxazole moieties on melanin synthesis in B16 cells and inhibition on bacteria. |
| AID533362 | Antimicrobial activity against Bacteroides thetaiotaomicron by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID318712 | Antimicrobial activity against Streptococcus agalactiae by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID427675 | Antimicrobial activity against Escherichia coli ATCC 6051 after 24 hrs by dilution susceptibility assay | 2009 | Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13 | Synthesis and antimicrobial activity of 4-hydroxy-4-(pyridyl)alk-3-en-2-ones. |
| AID533632 | Antimicrobial activity against Propionibacterium acnes by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID1399491 | Antibacterial activity against Bacillus cereus after 24 hrs by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID306206 | Antimicrobial activity against Escherichia coli | 2007 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 17, Issue:5 | Anti-mycobacterial activity of a bis-sulfonamide. |
| AID534723 | Antimicrobial activity against Bacteroides ovatus by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID324212 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoU mutant assessed as cell count in log phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID426128 | Antimicrobial activity against Staphylococcus aureus ATCC 259233 at 10 ug after 18 hrs by agar-well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities. |
| AID1180295 | Antimicrobial activity against Escherichia coli NCIM-2256 after 20 hrs by two fold serial macrodilution technique | 2014 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15 | One pot three components microwave assisted and conventional synthesis of new 3-(4-chloro-2-hydroxyphenyl)-2-(substituted) thiazolidin-4-one as antimicrobial agents. |
| AID568630 | Antibacterial activity against Staphylococcus aureus CGMCC 1.24465 after 24 hrs | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1 | N-hydroxypyridones, phenylhydrazones, and a quinazolinone from Isaria farinosa. |
| AID582898 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87T mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID574169 | Antibacterial activity against Escherichia coli MG1655 harboring plasmid pBR322 carrying blaTEM-1 and tetA(C) genes grown as planktonic cells after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID568330 | Antimicrobial activity against multidrug-resistant Escherichia coli by broth dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 21, Issue:4 | Design and synthesis of potent Gram-negative specific LpxC inhibitors. |
| AID209402 | Minimum inhibitory concentration against aerobic organisms Streptococcus faecalis strain 2864 | 1982 | Journal of medicinal chemistry, Apr, Volume: 25, Issue:4 | Quaternary heterocyclylamino beta-lactams: a generic alternative to the classical acylamino side chain. |
| AID244827 | Minimal inhibitory concentration against Escherichia coli | 2004 | Bioorganic & medicinal chemistry letters, Dec-06, Volume: 14, Issue:23 | Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: a structure-activity evaluation study. |
| AID535459 | Antimicrobial activity against Propionibacterium acnes by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID565004 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID600679 | Bactericidal activity against Staphylococcus aureus ATCC 6538 after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID535441 | Antimicrobial activity against Holdemania filiformis by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1774186 | Antibacterial activity against wild type Escherichia coli BW25113 assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID544533 | Antimicrobial activity against Escherichia coli DH5[alpha] isolate GC 8130 expressing bla SHV-1 gene by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Pyrosequencing using the single-nucleotide polymorphism protocol for rapid determination of TEM- and SHV-type extended-spectrum beta-lactamases in clinical isolates and identification of the novel beta-lactamase genes blaSHV-48, blaSHV-105, and blaTEM-155 |
| AID572245 | Antibacterial activity against Streptococcus constellatus by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID585853 | Antimicrobial activity against Pseudomonas aeruginosa isolate 7 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID567474 | Antimicrobial activity against gBLPACR-1 Haemophilus influenzae by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | In vitro activity of tebipenem, a new oral carbapenem antibiotic, against beta-lactamase-nonproducing, ampicillin-resistant Haemophilus influenzae. |
| AID325446 | Antibacterial activity against Salmonella enterica serovar Typhimurium LT2 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID304969 | Antibacterial activity against Escherichia coli by broth micro-dilution technique | 2007 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1 | New antifungal flavonoid glycoside from Vitex negundo. |
| AID293862 | Antibacterial activity against methicillin-resistant Staphylococcus aureus CMAH 0515 after 24 hrs by two fold dilution method | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6 | Synthesis of pseudopeptides based L-tryptophan as a potential antimicrobial agent. |
| AID1462724 | Antimicrobial activity against Candida albicans MTCC 227 | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20 | Benzothiazole analogues: Synthesis, characterization, MO calculations with PM6 and DFT, in silico studies and in vitro antimalarial as DHFR inhibitors and antimicrobial activities. |
| AID373675 | Antibacterial activity against Micrococcus luteus ATCC 10240 after 24 hrs by broth microdilution method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID278262 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS14 acrAB::Kan with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID519993 | Antimicrobial activity against vancomycin-resistant Enterococcus faecium nosocomial isolate | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID1359446 | Antibacterial activity against Bacillus subtilis NCIM 2079 after 12 hrs by serial dilution method | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Antibacterial and anti-TB tat-peptidomimetics with improved efficacy and half-life. |
| AID535346 | Antimicrobial activity against Streptococcus pneumoniae clinical isolates assessed as susceptible isolates by PK/PD technique | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Antimicrobial resistance among respiratory pathogens in Spain: latest data and changes over 11 years (1996-1997 to 2006-2007). |
| AID1235346 | Antimicrobial activity against Streptococcus pyogenes 345/1 assessed as zone of inhibition at 2862 uM incubated overnight at 37 degC | 2015 | Journal of natural products, Jul-24, Volume: 78, Issue:7 | Phytochemical Investigation of the Constituents Derived from the Australian Plant Macropidia fuliginosa. |
| AID1364564 | Antimicrobial activity against Candida albicans incubated for 24 hrs by CLSI protocol based method | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | Identification of Pyridinium with Three Indole Moieties as an Antimicrobial Agent. |
| AID685141 | Antibacterial activity against Klebsiella pneumoniae ATCC 27736 after 24 hrs by broth microdilution method | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Micelles catalyzed chemo- and regio-selective one pot and one step synthesis of 2,3,5,6-tetrakis(alkyl and arylsulfanyl)-1,4-benzoquinones and 2,5-diaminosubstituted-1,4-benzoquinones "In-Water" and their biological evaluation as antibacterial and antifun |
| AID587244 | Antimicrobial activity against Pseudomonas aeruginosa DSM 1128 at 1 ug/ul after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID1185311 | Antibacterial activity Bacillus Bacillus subtilis ATCC 6633 assessed as growth inhibition after 24 hrs by twofold serial dilution technique | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis and 3D-QSAR studies of new diphenylamine containing 1,2,4-triazoles as potential antitubercular agents. |
| AID1462722 | Antimicrobial activity against Escherichia coli MTCC 443 | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20 | Benzothiazole analogues: Synthesis, characterization, MO calculations with PM6 and DFT, in silico studies and in vitro antimalarial as DHFR inhibitors and antimicrobial activities. |
| AID614156 | Antimicrobial activity against Escherichia coli ATCC 35270 | 2011 | Journal of natural products, Aug-26, Volume: 74, Issue:8 | Sesterterpenes from the tropical sponge Coscinoderma sp. |
| AID519640 | Antimicrobial activity against Escherichia coli AB14156 harboring beta-lactamase CTX-M-42 Pro167Thr mutant gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID324235 | Antibacterial activity against Escherichia coli K12 containing PhoU mutant assessed as cell count in stationary phase at 100 ug/ml after 1 week | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1774196 | Antibacterial activity against Escherichia coli delta fepB assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID561724 | Antibacterial activity against Enterococcus faecium assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID564893 | Antibacterial activity against wild-type Escherichia coli AG100 harboring marR mutant gene at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID442426 | Antimicrobial activity against Staphylococcus aureus after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID535485 | Antimicrobial activity against Ruminococcus luti by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID586085 | Antimicrobial activity against verocytotoxin-producing Escherichia coli isolate O157 obtained from human assessed as percentage of resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID1424744 | Antimicrobial activity against Escherichia coli ATCC 12435 after 24 hrs by two-fold serial dilution method | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | New pyrazolopyridine analogs: Synthesis, antimicrobial, antiquorum-sensing and antitumor screening. |
| AID278521 | Antimicrobial activity against Bifidobacterium animalis ATCC 27536 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID369441 | Antibacterial activity against vancomycin-susceptible Enterococcus faecium after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID558318 | Antibacterial activity against Campylobacter jejuni by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID70152 | Minimum inhibitory concentration against 30 strains of Escherichia coli | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8 | Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives. |
| AID535211 | Antimicrobial activity against Clostridium spiroforme by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID562592 | Antimicrobial activity against Enterococcus faecalis expressing VanB gene clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1888847 | Antibacterial activity against Staphylococcus aureus 1199 measured after 24 hrs by Muller Hinton broth based MTT assay | 2022 | Bioorganic & medicinal chemistry, 01-15, Volume: 54 | Potentiating the intracellular killing of Staphylococcus aureus by dihydroquinazoline analogues as NorA efflux pump inhibitor. |
| AID252617 | Mean lysis diameter of Enterobacter aerogenes EA289 with D113A mutation by standard disk diffusion method on MH agar | 2005 | Journal of medicinal chemistry, Mar-10, Volume: 48, Issue:5 | Beta-lactam screening by specific residues of the OmpF eyelet. |
| AID535429 | Antimicrobial activity against Eubacterium biforme by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID558332 | Antibacterial activity against Campylobacter jejuni isolate P338 harboring blaOXA-61::cat gene by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID1233736 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as microbial growth inhibition at 1 mg/ml incubated overnight at 37 degC | 2015 | Journal of natural products, Jul-24, Volume: 78, Issue:7 | HPLC-NMR and HPLC-MS Profiling and Bioassay-Guided Identification of Secondary Metabolites from the Australian Plant Haemodorum spicatum. |
| AID520715 | Antibacterial activity against Acinetobacter baumannii CIP7010 by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID565014 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus simulans assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID523890 | Antimicrobial activity against Acinetobacter baumannii ATCC 15151 by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan. |
| AID1079945 | Animal toxicity known. [column 'TOXIC' in source] | |||
| AID293873 | Antimicrobial activity against Micrococcus luteus CMCC(B) 28001 after 24 hrs by two fold dilution method | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6 | Synthesis of pseudopeptides based L-tryptophan as a potential antimicrobial agent. |
| AID382708 | Antimicrobial activity against Staphylococcus epidermidis at 572.4 uM by disc-diffusion method | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives. |
| AID543796 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID295095 | Antibacterial activity against Escherichia coli ATCC 11230 at 10 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID508596 | Antibacterial activity against ciprofloxacin-resistant Salmonella enteritidis 5408 harboring gyrA D87Y mutant, gyrB E466D mutant, parE V461G mutant and ramR G25A mutant gene after 200 passages by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Fitness costs and stability of a high-level ciprofloxacin resistance phenotype in Salmonella enterica serotype enteritidis: reduced infectivity associated with decreased expression of Salmonella pathogenicity island 1 genes. |
| AID565006 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID559697 | Antibacterial activity against Escherichia coli TOP10 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | First report of plasmid-mediated quinolone resistance determinant qnrS1 in an Escherichia coli strain of animal origin in Italy. |
| AID495797 | Activity at Pseudomonas fluorescens PF-1 beta-lactamase BIC-1 expressed in Escherichia coli DH10B carrying pSau1 | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Novel ambler class A carbapenem-hydrolyzing beta-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France. |
| AID1527495 | Antimicrobial activity against multi drug-resistant Escherichia coli assessed as reduction in microbial growth after 24 to 48 hrs by microdilution susceptibility test | 2020 | European journal of medicinal chemistry, Jan-01, Volume: 185 | Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents. |
| AID285201 | Antimicrobial activity against Escherichia coli M104 mutant with AG100 dupIS3 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID548478 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSn mutant gene after 24 hrs by Etest in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID562229 | Antimicrobial activity against Desulfovibrio desulfuricans MB in presence of Sulbactam by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID533418 | Antimicrobial activity against Micromonas micros by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID757696 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 assessed as growth inhibition after 24 to 48 hrs by kirby-bauer disc diffusion method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis, antitumor and antibacterial activities of some novel tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives. |
| AID1286510 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 20 to 24 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID530206 | Antimicrobial activity against Mycobacterium bovis BCG ML1064 carrying transposon IS1096::Km inserted at +569bp of lppB gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID287237 | Antimicrobial activity against Pseudomonas aeruginosa IFO 3448 at 100 ug/disc | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles. |
| AID324288 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoBR mutant assessed as cell count in log phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1491296 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 16 to 20 hrs | 2017 | European journal of medicinal chemistry, Sep-08, Volume: 137 | QSAR-driven design, synthesis and discovery of potent chalcone derivatives with antitubercular activity. |
| AID543431 | Activity at Shigella sonnei UIH-1 beta-lactamase CTX-M-64 by spectrophotometry | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime. |
| AID1114819 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 to 24 hr by double microdilution method | 2013 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, Aug, Volume: 22, Issue:8 | |
| AID1634722 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by microdilution assay | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | 18β-Glycyrrhetinic Acid Derivatives Possessing a Trihydroxylated A Ring Are Potent Gram-Positive Antibacterial Agents. |
| AID1769807 | Antimicrobial activity against Staphylococcus aureus Sau 991 assessed as inhibition of bacterial growth incubated for 16 to 18 hrs by broth micro dilution technique | |||
| AID542773 | Antimicrobial activity against Escherichia coli J53 transformed with pHNPA1 carrying qnrB6 gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID559897 | Antimicrobial activity against Klebsiella oxytoca KO280 harboring beta-lactamase OXY-1 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | First detection of plasmid-encoded blaOXY beta-lactamase. |
| AID535461 | Antimicrobial activity against Propionibacterium avidum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID534995 | Antimicrobial activity against Clostridium butyricum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID546960 | Antibacterial activity against Yersinia enterocolitica by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1143597 | Antibacterial activity against Enterococcus assessed as growth inhibition after 24 hrs by two fold serial dilution method | 2014 | European journal of medicinal chemistry, Jun-23, Volume: 81 | Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-arylethanones: antibacterial, DNA photocleavage, and anticancer activities. |
| AID546969 | Antibacterial activity against Aeromonas caviae by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID512145 | Antibacterial activity against Escherichia coli MTCC 41 after 12 to 16 hrs by turbidity assay | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antiviral and antibacterial agents. |
| AID324292 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoB mutant assessed as cell count in log phase at 100 ug/ml after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID555462 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 67 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID520383 | Antimicrobial activity Escherichia coli DH5alpha expressing metallo-beta-lactamase VIM-11 by agar macrodilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain. |
| AID532675 | Antimicrobial activity against ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. |
| AID535465 | Antimicrobial activity against Anaerococcus prevotii by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID405081 | Antimicrobial activity against Escherichia coli CAG12177 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Biochemical characterization of PER-2 and genetic environment of blaPER-2. |
| AID573363 | Antibacterial activity against ceftazidime-nonsusceptible Klebsiella pneumoniae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID519634 | Ratio of Kcat to Km for beta-lactamase FUS1 assessed as compound hydrolysis by spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442. |
| AID564892 | Antibacterial activity against ompF-deficient Escherichia coli AG100 at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID585842 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID533124 | Antimicrobial activity against Bacteroides distasonis by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID564228 | Activity of Escherichia coli TOP10 beta-lactamase OXA-143 | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | OXA-143, a novel carbapenem-hydrolyzing class D beta-lactamase in Acinetobacter baumannii. |
| AID533390 | Antimicrobial activity against Clostridium perfringens by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID255541 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 2.0 uM/ml in dimethylformamide, + = resistant | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID529572 | Antimicrobial activity against Erwinia carotovora subsp. atroseptica DSM 30184 after 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora. |
| AID634988 | Antibacterial activity against drug-sensitive Staphylococcus epidermidis ATCC 12228 by broth microdilution method | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1 | Studies on the synthesis and antibacterial activity of 3,6-disubstituted 1,2,4-triazolo[3,4-b]1,3,4-thiadiazoles. |
| AID564822 | Bactericidal activity against methicillin-resistant Staphylococcus aureus after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID546957 | Antibacterial activity against Shigella dysenteriae by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1382101 | Antibacterial activity against Escherichia coli ATCC 35218 after 18 to 24 hrs by double microdilution method | 2018 | European journal of medicinal chemistry, Feb-25, Volume: 146 | Ciprofloxacin derivatives and their antibacterial activities. |
| AID1262361 | Antibacterial activity against clinical isolates Proteus vulgaris after 24 hrs by agar diffusion assay | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | PPL catalyzed four-component PASE synthesis of 5-monosubstituted barbiturates: Structure and pharmacological properties. |
| AID360064 | Inhibition of Enterococcus faecium M512 LDtfm transpeptidase activity assessed as tri-aspartate-tri-aspartate-tri-aspartate multimer containing L-Lys3 to D-Asp-L-Lys3 cross links at 8 ug/ml | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID557740 | Antimicrobial activity in Peptoniphilus asaccharolyticus by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1157885 | Antimicrobial activity against Escherichia coli ATCC 35270 after 24 hrs by two-fold broth dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Suvanine sesterterpenes and deacyl irciniasulfonic acids from a tropical Coscinoderma sp. sponge. |
| AID633491 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by two fold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial activity of brominated resorcinol dimers. |
| AID530225 | Antimicrobial activity against Mycobacterium bovis BCG ML1037 carrying transposon IS1096::Km inserted at +1765bp of bcg3693 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1164943 | Antimicrobial activity against Escherichia coli K-12 by microbroth dilution method | 2014 | Journal of medicinal chemistry, Oct-23, Volume: 57, Issue:20 | Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives. |
| AID559327 | Antimicrobial activity against Salmonella enterica serovar Infantis assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID373682 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by broth microdilution method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID555252 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 67 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID425601 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM605 in mouse J774A1 cells isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as intracellular killing of bacteria at 10% compound Cmax a | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID1577944 | Antimicrobial activity against Pseudomonas aeruginosa under iron-sufficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID561726 | Antibacterial activity against Enterococcus faecalis assessed as resistant isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID1287092 | Antimicrobial activity against antibiotic resistant Candida albicans clinical isolate 08030401 after 16 hrs by broth dilution method | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis. |
| AID545427 | Antimicrobial activity against Enterobacter aerogenes obtained from patient with complicated intra-abdominal infection assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID293864 | Antimicrobial activity against Bacillus subtilis after 24 hrs by two fold dilution method | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6 | Synthesis of pseudopeptides based L-tryptophan as a potential antimicrobial agent. |
| AID487479 | Antibacterial activity against Escherichia coli NCIM 2065; ATCC 8739 after 24 hrs by microtitration method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Design, synthesis, characterization, and antibacterial activity of {5-chloro-2-[(3-substitutedphenyl-1,2,4-oxadiazol-5-yl)-methoxy]-phenyl}-(phenyl)-methanones. |
| AID520875 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus saprophyticus isolates isolated from genitourinary tracts of acute cystitis patient after 24 hrs at 35 degC by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Methicillin-resistant Staphylococcus saprophyticus isolates carrying staphylococcal cassette chromosome mec have emerged in urogenital tract infections. |
| AID1159101 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID429266 | Antibacterial activity against Salmonella Typhimurium at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents. |
| AID519122 | Antibacterial activity against Proteus mirabilis NP55 after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID557728 | Antimicrobial activity in Finegoldia magna by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID557454 | Antimicrobial activity in Prevotella intermedia by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID372550 | Antibacterial activity against genetically beta-lactamase-positive amoxicillin-clavulanate-resistant Haemophilus influenzae type b with an amino acid substitution in variable mutated locus Asn-526 or Arg-517 of ftsI gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID546948 | Antibacterial activity against Shigella sonnei by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID561514 | Antibacterial activity against Enterococcus faecalis by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID565008 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID567279 | Activity of Acinetobacter baumannii ADC-33 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Extended-spectrum cephalosporinase in Acinetobacter baumannii. |
| AID1399258 | Antimicrobial activity against Streptococcus pneumoniae R6 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID567585 | Antimicrobial activity against Acinetobacter baumannii by broth dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | In vitro antimicrobial activity and mutant prevention concentration of colistin against Acinetobacter baumannii. |
| AID585836 | Antimicrobial activity against ampD, ampDh2, ampDh3 and ampG deficient Pseudomonas aeruginosa PAO1 harboring pUCP24 conferring resistance to gentamycin after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl- | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID623615 | Antibacterial activity against 10'8 CFU/mL Klebsiella pneumoniae MTCC 109 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID294830 | Antibacterial activity against Staphylococcus aureus after 24 hrs by microdilution broth method | 2007 | Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8 | Identification of antitumour activity of novel derivatives of 8-aryl-2,6,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazine-3,4-dione and 8-aryl-4-imino-2,3,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazin-3(6H)-one. |
| AID373679 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by broth microdilution method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID559325 | Antimicrobial activity against Shigella flexneri assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID1457512 | Antibacterial activity against Bacillus subtilis assessed as inhibition of peptidoglycan synthesis at 2 mg/L after 50 mins by [3H]-N-acetylglucosamine incorporation assay | 2017 | Journal of medicinal chemistry, 07-27, Volume: 60, Issue:14 | Lipophosphonoxins II: Design, Synthesis, and Properties of Novel Broad Spectrum Antibacterial Agents. |
| AID573379 | Antibacterial activity against beta lactamase-negative Haemophilus influenzae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID565060 | Antibacterial activity against wild-type Escherichia coli AG100 harboring IS186 insertion in lon3 gene at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID573337 | Antibacterial activity against ceftazidime-nonsusceptible Enterobacteriaceae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1870156 | Antibacterial activity against wild type Staphylococcus aureus 4515/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID565012 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus simulans after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID777336 | Antibacterial activity against Pseudomonas aeruginosa ATCC BAA427 assessed as growth inhibition after 24 hrs by microbroth dilution method | 2013 | ACS medicinal chemistry letters, Oct-10, Volume: 4, Issue:10 | Identification of 1-[4-Benzyloxyphenyl)-but-3-enyl]-1H-azoles as New Class of Antitubercular and Antimicrobial Agents. |
| AID609457 | Antibacterial activity against Staphylococcus aureus after 24 hrs by broth dilution method | 2011 | Bioorganic & medicinal chemistry, Aug-01, Volume: 19, Issue:15 | Synthesis of some new [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4] thiadiazoles starting from 5-nitro-2-furoic acid and evaluation of their antimicrobial activity. |
| AID536076 | Antimicrobial activity against Staphylococcus aureus IFO 3060 at 100 ug/8 mm disk after 24 hrs by agar disk diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID1157883 | Antimicrobial activity against Salmonella enterica ATCC 14028 after 24 hrs by two-fold broth dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Suvanine sesterterpenes and deacyl irciniasulfonic acids from a tropical Coscinoderma sp. sponge. |
| AID557799 | Antimicrobial activity against Escherichia coli J53 by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. |
| AID584300 | Antibacterial activity against mecA-negative Staphylococcus fleurettii SFMN02 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID585850 | Antimicrobial activity against Pseudomonas aeruginosa isolate 5 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID519252 | Antibacterial activity against Proteus mirabilis M 26 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID520721 | Antibacterial activity against Escherichia coli DH10B harboring pOXA-97 | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID1204969 | Antimicrobial activity against Proteus hauseri NBRC 3851 after 24 hrs by twofold dilution method | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Additional sesterterpenes and a nortriterpene saponin from the sponge Clathria gombawuiensis. |
| AID460802 | Antibacterial activity against Acinetobacter baumannii AB0043 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID555470 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 109 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID524827 | Antibacterial activity against erythromycin susceptible Campylobacter sp. assessed as resistance breakpoint by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID419827 | Antibacterial activity against Staphylococcus aureus MTCC 96 at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Jun, Volume: 44, Issue:6 | Physicochemical and biological characterization of novel macrocycles derived from o-phthalaldehyde. |
| AID572236 | Antibacterial activity against Ruminococcus productus by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1290445 | Antifungal activity against Candida albicans MTCC 227 after 24 to 48 hrs by broth microdilution method | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities. |
| AID64742 | Influence of porins and TonB on antibacterial activity in Escherichia coli (BR158) using agar diffusion assay | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID535467 | Antimicrobial activity against Anaerococcus tetradius by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID584294 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus fleurettii SFMP04 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID333995 | Antibacterial activity against Pseudomonas aeruginosa at 100 ug/100 uL after 24 hrs by tube broth dilution method | 1997 | Journal of natural products, Oct, Volume: 60, Issue:10 | New steroidal alkaloids from Buxus longifolia. |
| AID534955 | Antimicrobial activity against Porphyromonas somerae by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1668056 | Inhibition of DHPS in Proteus vulgaris assessed as antibacterial activity by measuring inhibition zone at 5 mg/mL incubated for 24 hrs by disk diffusion method | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9 | New acrylamide-sulfisoxazole conjugates as dihydropteroate synthase inhibitors. |
| AID662078 | Antibacterial activity against Escherichia coli after 20 hrs by liquid growth inhibition assay | 2012 | Journal of medicinal chemistry, Mar-08, Volume: 55, Issue:5 | From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity. |
| AID509702 | Antibacterial activity against Staphylococcus epidermidis after 24 hrs by tube dilution method | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of some 3-substituted amino-4,5-tetramethylene thieno[2,3-d][ 1,2,3]-triazin-4(3H)-ones as potential antimicrobial agents. |
| AID535358 | Antimicrobial activity against Streptococcus pyogenes clinical isolates assessed as susceptible isolates by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Antimicrobial resistance among respiratory pathogens in Spain: latest data and changes over 11 years (1996-1997 to 2006-2007). |
| AID1265772 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 by two-fold serial dilution method | 2016 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 26, Issue:1 | Discovery of bisindolyl-substituted cycloalkane-anellated indoles as novel class of antibacterial agents against S. aureus and MRSA. |
| AID655628 | Antibacterial activity against Salmonella typhimurium ATCC 23564 at 160 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID425612 | Cytotoxicity against mouse J774A1 cells assessed as release of adenylate kinase at 100 ug/ml after 3 hrs by total cell protein assay relative to control | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID1331872 | Antibacterial activity against vancomycin-resistant Enterococcus | 2017 | Bioorganic & medicinal chemistry, 01-01, Volume: 25, Issue:1 | Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. |
| AID548000 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237N mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID557462 | Antimicrobial activity in Prevotella corporis by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID206069 | IIn vitro inhibitory activity against Streptococci EryR (27);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID426126 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 at 10 ug after 18 hrs by agar-well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities. |
| AID630653 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs | 2011 | Bioorganic & medicinal chemistry, Nov-01, Volume: 19, Issue:21 | Synthesis, molecular modeling and preliminary biological evaluation of a set of 3-acetyl-2,5-disubstituted-2,3-dihydro-1,3,4-oxadiazole as potential antibacterial, anti-Trypanosoma cruzi and antifungal agents. |
| AID546926 | Antibacterial activity against Salmonella enterica serovar Typhimurium assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID519472 | Antimicrobial activity against Stenotrophomonas maltophilia K279a harboring -121 frameshift mutation in ampR gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Induction of L1 and L2 beta-lactamase production in Stenotrophomonas maltophilia is dependent on an AmpR-type regulator. |
| AID477778 | Antimicrobial activity Escherichia coli at 2 mg/mL after 24 hrs by agar diffusion technique | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and study of some new 1,3-isoindoledione derivatives as potential antibacterial agents. |
| AID1163966 | Antibacterial activity against Escherichia coli KCTC-1924 after 24 hrs by twofold dilution method | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Anti-tyrosinase, antioxidant, and antibacterial activities of novel 5-hydroxy-4-acetyl-2,3-dihydronaphtho[1,2-b]furans. |
| AID392752 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate after 18 to 24 hrs by tube dilution method | 2009 | Bioorganic & medicinal chemistry, Feb-15, Volume: 17, Issue:4 | Synthesis and antimicrobial evaluation of some new substituted purine derivatives. |
| AID555259 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 90 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID600682 | Bactericidal activity against Listeria monocytogenes NCTC 7973 after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID1617944 | Antibacterial activity against Escherichia coli ATCC 12435 after 16 to 48 hrs | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12 | Structure Determination, Functional Characterization, and Biosynthetic Implications of Nybomycin Metabolites from a Mining Reclamation Site-Associated |
| AID1439798 | Antibacterial activity against Bacillus subtilis MTCC 121 at 100 ug incubated for 24 hrs under dark condition by agar well diffusion method | 2017 | Bioorganic & medicinal chemistry letters, 04-01, Volume: 27, Issue:7 | Biologically active perspective synthesis of heteroannulated 8-nitroquinolines with green chemistry approach. |
| AID657440 | Antibacterial activity against Escherichia coli clinical isolate after 16 hrs by 2-fold microdilution method | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9 | Preparation, antibacterial evaluation and preliminary structure-activity relationship (SAR) study of benzothiazol- and benzoxazol-2-amine derivatives. |
| AID1159097 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID544585 | Antimicrobial activity against Escherichia coli DH5[alpha] isolate GC 8133 expressing bla TEM-55 gene by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Pyrosequencing using the single-nucleotide polymorphism protocol for rapid determination of TEM- and SHV-type extended-spectrum beta-lactamases in clinical isolates and identification of the novel beta-lactamase genes blaSHV-48, blaSHV-105, and blaTEM-155 |
| AID1183256 | Antimicrobial activity against Bacillus subtilis MTCC 441 assessed as absence of visible growth after 24 to 48 hrs by broth micro dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis and characterization of fluoro substituted novel pyrazolylpyrazolines scaffold and their pharmacological screening. |
| AID534961 | Antimicrobial activity against Prevotella corporis by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID535481 | Antimicrobial activity against Ruminococcus gnavus by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID535487 | Antimicrobial activity against Ruminococcus obeum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID546933 | Antibacterial activity against Salmonella enterica serovar Paratyphi by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID463404 | Antimicrobial activity against Streptococcus pyogenes at 1000 ug after 24 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines. |
| AID587193 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus after 18 hrs by broth microdilution method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Comazaphilones A-F, azaphilone derivatives from the marine sediment-derived fungus Penicillium commune QSD-17. |
| AID324225 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoU mutant assessed as cell count in stationary phase at 100 ug/ml after 3 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID558538 | Antibacterial activity against bla-positive and beta-lactamase-weakly positive Campylobacter coli isolate P1627 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID562938 | Upregulation of cwp84 gene expression in Clostridium difficile 6269 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID572033 | Antibacterial activity against Clostridium beijerinckii by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID535469 | Antimicrobial activity against Finegoldia magna by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID572263 | Antibacterial activity against Prevotella nigrescens by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1399271 | Antimicrobial activity against Klebsiella pneumoniae isolate SJ 4 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID405316 | Antibacterial activity against Haemophilus influenzae group IIc isolates with ftsI gene mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID533402 | Antimicrobial activity against Clostridium subterminale by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID528608 | Ratio of Kcat to Km for Escherichia coli 2138 beta-lactamase KPC-2 by spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France. |
| AID587966 | Activity of Escherichia coli beta-lactamase Toho-1 F160T mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID289622 | Antibacterial activity against Pseudomonas aeruginosa after 24 hrs by micro-broth dilution technique | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, in vitro antibacterial and antifungal evaluations of 2-amino-4-(1-naphthyl)-6-arylpyrimidines. |
| AID572038 | Antibacterial activity against Clostridium glycolicum by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID562939 | Effect on fbp69 gene expression in Clostridium difficile 6425 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID1143594 | Antibacterial activity against Escherichia coli assessed as growth inhibition after 24 hrs by two fold serial dilution method | 2014 | European journal of medicinal chemistry, Jun-23, Volume: 81 | Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-arylethanones: antibacterial, DNA photocleavage, and anticancer activities. |
| AID583091 | Activity of Escherichia coli XL1-Blue wild-type IMP-1 beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID544288 | Antimicrobial activity against Enterococcus faecalis NKH18 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID572233 | Antibacterial activity against Ruminococcus flavefaciens by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1262359 | Antibacterial activity against clinical isolate Gram-positive Bacillus subtilis after 24 hrs by agar diffusion assay | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | PPL catalyzed four-component PASE synthesis of 5-monosubstituted barbiturates: Structure and pharmacological properties. |
| AID1347487 | Antibacterial activity against Staphylococcus epidermidis assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID534997 | Antimicrobial activity against Clostridium cadaveris by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID655616 | Antibacterial activity against Escherichia coli ATCC 35218 at 160 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID535183 | Antimicrobial activity against Clostridium disporicum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID573338 | Antibacterial activity against ceftazidime-nonsusceptible Enterobacteriaceae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1821107 | Antibacterial activity against Enterococcus faecium ATCC 19434 assessed as inhibition of bacterial growth incubated for 24 hr by CLSI based broth microdilution method | |||
| AID1887297 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as inhibition of bacterial growth incubated for 24 hrs by optical density based analysis | 2022 | Journal of natural products, 09-23, Volume: 85, Issue:9 | Total Syntheses and Antibacterial Evaluations of Neocyclomorusin and Related Flavones. |
| AID345810 | Antimicrobial activity against Candida maltosa | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24 | Synthesis and antimicrobial activity of 2-alkenylchroman-4-ones, 2-alkenylthiochroman-4-ones and 2-alkenylquinol-4-ones. |
| AID1399266 | Antimicrobial activity against Proteus mirabilis ATCC 25933 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID582900 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87S mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID546964 | Antibacterial activity against Yersinia pseudotuberculosis assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID534963 | Antimicrobial activity against Prevotella disiens by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID495321 | Antimicrobial activity against beta-lactamase-negative, ampicillin-sensitive Haemophilus influenzae by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID1076000 | Antibacterial activity against Staphylococcus aureus NCIM 2901 by standard agar method | 2014 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 24, Issue:6 | Synthesis, antileishmanial activity and docking study of N'-substitutedbenzylidene-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetohydrazides. |
| AID1896844 | Antibacterial activity against Salmonella typhi CMCC50094 assessed as prevention of visible growth by broth microdilution method | |||
| AID520385 | Activity at Pseudomonas aeruginosa M5109 metallo-beta-lactamase VIM-11 by spectrometry | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain. |
| AID278228 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21 | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID494535 | Antimicrobial activity against Salmonella typhi NCIM 2501 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID494535 | Antimicrobial activity against Salmonella typhi NCIM 2501 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May-06 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID758275 | Antibacterial activity against Bacillus subtilis MTCC 441 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Design and synthesis of biquinolone-isoniazid hybrids as a new class of antitubercular and antimicrobial agents. |
| AID727795 | Antimicrobial activity against Escherichia coli DH10B expressing Beta-lactamase SHV-1 K234A protein mutant by CLSI agar dilution method | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3 | Design and exploration of novel boronic acid inhibitors reveals important interactions with a clavulanic acid-resistant sulfhydryl-variable (SHV) β-lactamase. |
| AID289624 | Antifungal activity against Microsporum gypseum after 7 days | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, in vitro antibacterial and antifungal evaluations of 2-amino-4-(1-naphthyl)-6-arylpyrimidines. |
| AID557418 | Antimicrobial activity in Bacteroides ovatus by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID389388 | Antibacterial activity against Salmonella Typhimurium ATCC 14028 | 2008 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 18, Issue:20 | Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp. |
| AID534993 | Antimicrobial activity against Clostridium bolteae by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID304974 | Antifungal activity against Sporothrix schenckii by broth micro-dilution technique | 2007 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1 | New antifungal flavonoid glycoside from Vitex negundo. |
| AID548529 | Antimicrobial activity against Vancomycin-susceptible Enterococcus faecalis by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID456078 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID572048 | Antibacterial activity against Clostridium tertium by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID633856 | Antibacterial activity against Staphylococcus aureus ATCC 6538 incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID613614 | Antibacterial activity against 10'8 CFU/mL Vibrio cholerae MTCC 3906 by NCCLS M100-S12(M7) broth microdilution method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis and identification of β-aryloxyquinolines and their pyrano[3,2-c]chromene derivatives as a new class of antimicrobial and antituberculosis agents. |
| AID545657 | Antimicrobial activity against Stenotrophomonas maltophilia assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID528719 | Antibacterial activity against vancomycin resistant Enterococcus faecium VanA clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID557950 | Antimicrobial activity in Propionibacterium acnes by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID572052 | Antibacterial activity against Bifidobacterium bifidum by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1493670 | Antimicrobial activity against Staphylococcus epidermidis RCMB 010024 after overnight incubation by macro-tube dilution technique | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Quinoline derivatives bearing pyrazole moiety: Synthesis and biological evaluation as possible antibacterial and antifungal agents. |
| AID1774197 | Antibacterial activity against Escherichia coli delta fepD assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID372552 | Antibacterial activity against genetically beta-lactamase-negative ampicillin-resistant Haemophilus influenzae type b with bla gene but without an amino acid substitution in ftsI gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID584329 | Antibacterial activity against gspS deficient Escherichia coli JW2956-1 | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Interplay between drug efflux and antioxidants in Escherichia coli resistance to antibiotics. |
| AID600672 | Antibacterial activity against Bacillus cereus clinical isolate after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID582918 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61Y mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1382084 | Antibacterial activity against Bacillus cereus 709 Roma after 18 to 24 hrs by double microdilution method | 2018 | European journal of medicinal chemistry, Feb-25, Volume: 146 | Ciprofloxacin derivatives and their antibacterial activities. |
| AID535203 | Antimicrobial activity against Clostridium scindens by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1439801 | Antibacterial activity against Escherichia coli MTCC 1652 incubated for 24 hrs under dark condition by microwell dilution method | 2017 | Bioorganic & medicinal chemistry letters, 04-01, Volume: 27, Issue:7 | Biologically active perspective synthesis of heteroannulated 8-nitroquinolines with green chemistry approach. |
| AID1504236 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by two fold serial dilution method | 2017 | Journal of natural products, 11-22, Volume: 80, Issue:11 | Nicrophorusamides A and B, Antibacterial Chlorinated Cyclic Peptides from a Gut Bacterium of the Carrion Beetle Nicrophorus concolor. |
| AID1372804 | Antimicrobial activity against Staphylococcus aureus ATCC 6538 by two-fold serial dilution assay | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2 | An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold. |
| AID534973 | Antimicrobial activity against Clostridium difficile by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID278543 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium pseudolongum ATCC 25562 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID460799 | Antibacterial activity against Acinetobacter baumannii ATCC 19606 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID1104311 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID587730 | Activity of Pseudomonas aeruginosa strain PS 297 metallo-beta-lactamase IMP-18 expressed in Escherichia coli BL21(DE3) assessed as substrate hydrolysis using 100 uM nitrocefin | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States. |
| AID534957 | Antimicrobial activity against Porphyromonas uenonis by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID557962 | Antimicrobial activity in Clostridium perfringens by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID759381 | Antibacterial activity against Proteus mirabilis NCTC 289 assessed as growth inhibition after 24 hrs by Kirby-Bauer disc diffusion method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis and biological evaluation of some novel thiazole compounds as potential anti-inflammatory agents. |
| AID535435 | Antimicrobial activity against Eubacterium limosum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1585549 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Benzofuran derivatives and their anti-tubercular, anti-bacterial activities. |
| AID587961 | Activity of Escherichia coli wild type beta-lactamase Toho-1 assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID85811 | The compound was tested in vitro for antibacterial activity against 39 strains of Haemophilus influenza AmpR; Value is 1.2/10 | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21 | Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens. |
| AID510750 | Antibacterial activity against Escherichia coli AG102MB harboring pS1328-based acrB gene | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. |
| AID535673 | Antimicrobial activity against beta-lactamase negative, ampicillin-resistant Haemophilus influenzae expressing fst1 mutant gene by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Genotypic versus phenotypic characterization, with respect to beta-lactam susceptibility, of Haemophilus influenzae isolates exhibiting decreased susceptibility to beta-lactam resistance markers. |
| AID572042 | Antibacterial activity against Clostridium paraputrificum by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID534969 | Antimicrobial activity against Prevotella melaninogenica by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID293867 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by two fold dilution method | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6 | Synthesis of pseudopeptides based L-tryptophan as a potential antimicrobial agent. |
| AID535439 | Antimicrobial activity against Eubacterium saburreum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID564833 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus hominis after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID520870 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus saprophyticus isolate TSU47 isolated from genitourinary tracts of acute cystitis patient after 24 hrs at 35 degC by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Methicillin-resistant Staphylococcus saprophyticus isolates carrying staphylococcal cassette chromosome mec have emerged in urogenital tract infections. |
| AID372557 | Antibacterial activity against genetically beta-lactamase-positive amoxicillin-clavulanate-resistant Haemophilus influenzae type b with an amino acid substitution in highly mutated locus Ser-385 of ftsI gene assessed as susceptibility rate by broth microd | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID549337 | Antimicrobial activity against Escherichia coli ATCC 25922 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID565005 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1647638 | Antibacterial activity against Enterococcus faecalis ATCC 19433 assessed as reduction in microbial growth | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Isocadiolides A-H: Polybrominated Aromatics from a |
| AID535193 | Antimicrobial activity against Clostridium leptum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID546963 | Antibacterial activity against Yersinia pseudotuberculosis by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID603040 | Antimicrobial activity against Pseudomonas aeruginosa at 1 ug/mL after 48 hrs by cup plate agar diffusion method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | Synthesis, antitumor and antimicrobial activities of 4-(4-chlorophenyl)-3-cyano-2-(β-O-glycosyloxy)-6-(thien-2-yl)-nicotinonitrile. |
| AID1143595 | Antibacterial activity against Klebsiella pneumoniae assessed as growth inhibition after 24 hrs by two fold serial dilution method | 2014 | European journal of medicinal chemistry, Jun-23, Volume: 81 | Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-arylethanones: antibacterial, DNA photocleavage, and anticancer activities. |
| AID559901 | Antimicrobial activity against Klebsiella pneumoniae 278sp by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | First detection of plasmid-encoded blaOXY beta-lactamase. |
| AID64744 | Influence of siderophore receptor on antibacterial activity in Escherichia coli (H1443) using agar diffusion assay | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID529609 | Antibacterial activity against Beta-lactamase negative Haemophilus influenzae isolate after 20 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID535231 | Antimicrobial activity against Bifidobacterium bifidum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID528527 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B8 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID536082 | Antimicrobial activity against Escherichia coli IFO 3301 at 100 ug/8 mm disk after 24 hrs by agar disk diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID360069 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as tetra-aspartate-tri-aspartate multimer containing D-Ala4 to D-Asp-L-Lys3 cross links at 128 ug/ml by mass spectrometry | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID360854 | Antibacterial activity against Stenotrophomonas maltophilia ATCC 13637 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID495798 | Ratio of Kcat to Km of Pseudomonas fluorescens PF-1 beta-lactamase BIC-1 expressed in Escherichia coli DH10B using nitrocefin hydrolysis | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Novel ambler class A carbapenem-hydrolyzing beta-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France. |
| AID294414 | Antimicrobial activity against Bacillus megaterium at 25 ug/mL by agar diffusion technique | 2007 | European journal of medicinal chemistry, Jul, Volume: 42, Issue:7 | Synthesis and antimicrobial evaluation of some new thiazole, thiazolidinone and thiazoline derivatives starting from 1-chloro-3,4-dihydronaphthalene-2-carboxaldehyde. |
| AID534082 | Antibacterial activity against cefotaxime-resistant Streptococcus pneumoniae isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro activity of ceftaroline against Streptococcus pneumoniae isolates exhibiting resistance to penicillin, amoxicillin, and cefotaxime. |
| AID678539 | Antibacterial activity against Shigella dysenteriae ATCC 32412 | 2012 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 22, Issue:18 | Design, solvent free synthesis, and antimicrobial evaluation of 1,4 dihydropyridines. |
| AID495347 | Antimicrobial activity against Beta-lactamase-positive, ampicillin-cluvulanate-resistant Haemophilus influenzae with Asp350Asn, Ala502Thr, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID299666 | Antibacterial activity against Micrococcus luteus CMCC(B)28001 by broth microdilution method | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Synthesis and evaluation of amphiphilic cationic quinine-derived for antibacterial activity against methicillin-resistant Staphylococcus aureus. |
| AID294963 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID534727 | Antimicrobial activity against Bacteroides caccae by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID547777 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237G mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID562220 | Antimicrobial activity against Desulfovibrio sp. by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID562930 | Antimicrobial activity against Clostridium difficile CD07-259 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID572040 | Antibacterial activity against Clostridium leptum by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID535634 | Antimicrobial activity against Group B streptococcus serotype VI R6 harboring F395L, V405A, R433H, H438Y, A374V and G648A mutations in PBP 2X and T567I mutation in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID1287096 | Antimicrobial activity against antibiotic resistant Candida albicans clinical isolate 08032815 after 16 hrs by broth dilution method | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis. |
| AID1287980 | Antibacterial activity against Bacillus subtilis after 18 hrs by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 26, Issue:7 | Facile synthesis of 1,3-thiazolidin-4-ones as antitubercular agents. |
| AID561938 | Antibacterial activity against blaOXA-24-positive Acinetobacter baumannii isolate VA-566/00 by CLSI broth microdilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Characterization of pABVA01, a plasmid encoding the OXA-24 carbapenemase from Italian isolates of Acinetobacter baumannii. |
| AID533132 | Antimicrobial activity against Bacteroides fragilis by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID324979 | Antibacterial activity against Haemophilus influenzae MSC01855 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID525581 | Activity of Beta-lactamase OXA-1 expressed in Escherichia coli BL21 (DE3) | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Penicillin sulfone inhibitors of class D beta-lactamases. |
| AID1056539 | Antibacterial activity against Acinetobacter baumannii ATCC 19606 by broth microdilution method | 2013 | Journal of natural products, Dec-27, Volume: 76, Issue:12 | Cytotoxic and antibacterial marfuraquinocins from the deep South China Sea-derived Streptomyces niveus SCSIO 3406. |
| AID1139540 | Antibacterial activity against Escherichia coli DH5alpha expressing beta-lactamase TEM-1 by CLSI broth microdilution method | 2014 | Journal of medicinal chemistry, May-08, Volume: 57, Issue:9 | Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. |
| AID1818974 | Antibacterial activity against Escherichia coli ATCC 12701 assessed as bacterial clearance incubated for 6 to 24 hrs by microbroth dilution method | 2022 | Journal of medicinal chemistry, 01-13, Volume: 65, Issue:1 | Discovery of |
| AID519011 | Ratio of Kcat to Km for Beta-lactamase TEM-149 T182M mutant expressed in Escherichia coli HB101 | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | E240V substitution increases catalytic efficiency toward ceftazidime in a new natural TEM-type extended-spectrum beta-lactamase, TEM-149, from Enterobacter aerogenes and Serratia marcescens clinical isolates. |
| AID572249 | Antibacterial activity against Bacteroides fragilis by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1156861 | Antimicrobial activity against vancomycin-resistant Staphylococcus aureus after 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents. |
| AID562813 | Antimicrobial activity against Escherichia coli DH5[alpha] harboring pEK516 plasmid encoding CTX-M extended-spectrum beta-lactamases | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID1868107 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolate 10B assessed as inhibition of visible bacterial growth incubated for 18 hrs by CLSI protocol based assay | 2022 | Journal of natural products, 05-27, Volume: 85, Issue:5 | Enceleamycins A-C, Furo-Naphthoquinones from |
| AID360063 | Inhibition of Enterococcus faecium M512 LDtfm transpeptidase activity assessed as tri-aspartate-penta-aspartate multimer containing L-Lys3 to D-Asp-L-Lys3 cross links at 8 ug/ml | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID1372807 | Bactericidal activity against Escherichia coli NCTC 10418 by two-fold serial dilution assay | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2 | An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold. |
| AID252634 | Bacterial susceptibility induced by D113 mutation in Escherichia coli OmpF | 2005 | Journal of medicinal chemistry, Mar-10, Volume: 48, Issue:5 | Beta-lactam screening by specific residues of the OmpF eyelet. |
| AID572028 | Antibacterial activity against Clostridium innocuum by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1132059 | Cytotoxicity against human HeLa cells by neutral red assay | 1978 | Journal of medicinal chemistry, Jan, Volume: 21, Issue:1 | Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. |
| AID531313 | Activity of Pseudomonas aeruginosa beta-lactamase VIM-7 by spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family. |
| AID590290 | Antifungal activity against Trichophyton rubrum IFO 9185 at 100 ug/ml after 2 weeks | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase. |
| AID557966 | Antimicrobial activity in Clostridium difficile by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID519124 | Antibacterial activity against Proteus mirabilis M 40 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID564820 | Bactericidal activity against methicillin-susceptible Staphylococcus aureus after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID525548 | Antimicrobial activity against ampicillin resistant nontypeable Haemophilus influenzae isolate BB1051 harboring with plasmid pB1000 bearing beta-lactamase ROB-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Haemophilus influenzae clinical isolates with plasmid pB1000 bearing blaROB-1: fitness cost and interspecies dissemination. |
| AID278239 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-2 tolC::Kan with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID531318 | Ratio of Kcat to Km for Escherichia coli beta-lactamase VIM-1 by spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family. |
| AID547177 | Antibacterial activity against Vibrio parahaemolyticus assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID557946 | Antimicrobial activity in Bifidobacterium by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID567473 | Antimicrobial activity against gBLPAR-TEM1 Haemophilus influenzae by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | In vitro activity of tebipenem, a new oral carbapenem antibiotic, against beta-lactamase-nonproducing, ampicillin-resistant Haemophilus influenzae. |
| AID1228007 | Antimicrobial activity against ampicillin-resistant Staphylococcus aureus ATCC 29213 assessed as complete prevention of visible growth after incubation at 37 degC for 18 to 20 hrs | 2015 | Journal of natural products, Apr-24, Volume: 78, Issue:4 | Antibacterial Biphenanthrenes from the Fibrous Roots of Bletilla striata. |
| AID535675 | Antimicrobial activity against beta-lactamase positive Haemophilus influenzae expressing fst1 gene assessed as resistant isolates by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Genotypic versus phenotypic characterization, with respect to beta-lactam susceptibility, of Haemophilus influenzae isolates exhibiting decreased susceptibility to beta-lactam resistance markers. |
| AID559336 | Antimicrobial activity against Shigella flexneri harboring carb-like gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID294191 | Antibacterial activity against Escherichia coli ATCC 25922 at 100 ug/ml by diffusion method | 2007 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 17, Issue:8 | Synthesis and antimicrobial activity of some novel phenyl and benzimidazole substituted benzyl ethers. |
| AID562589 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecium clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID584295 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus fleurettii SFMP05 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID534735 | Antimicrobial activity against Bilophila wadsworthia by Wadsworth agar dilution method in presence of 1% pyruvic acid and beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID547181 | Antibacterial activity against Vibrio alginolyticus assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID276385 | Antibacterial activity against Escherichia coli by broth microdilution technique | 2006 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 16, Issue:22 | Naphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: synthesis and biological evaluation as potential antibacterial and antifungal agents. |
| AID565056 | Antibacterial activity against wild-type Escherichia coli AG100 harboring IS186 insertion in lon3 gene and Tn5 insertion in ycgE gene at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID535640 | Antimicrobial activity against Group B streptococcus serotype Ib C2 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID1323302 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by serial two fold dilution method | 2016 | Journal of natural products, 07-22, Volume: 79, Issue:7 | Actinomadurol, an Antibacterial Norditerpenoid from a Rare Actinomycete, Actinomadura sp. KC 191. |
| AID562331 | Antimicrobial activity against Escherichia coli DH5alpha harboring metallo-beta-lactamase IND-6 after 18 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso. |
| AID546975 | Antibacterial activity against Aeromonas veronii by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID513158 | Inhibition of heme crystallization after 16 hrs | 2006 | Nature chemical biology, Aug, Volume: 2, Issue:8 | A clinical drug library screen identifies astemizole as an antimalarial agent. |
| AID524825 | Antibacterial activity against erythromycin susceptible Campylobacter sp. by agar plate dilution method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID572237 | Antibacterial activity against Ruminococcus torques by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID514128 | Antibacterial activity against clinical isolate of Escherichia coli assessed as growth inhibition at 1 mg/ml after 16 to 20 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays. |
| AID534382 | Antibacterial activity against Escherichia coli K-12 W1895 transconjugant harboring pCF243 by microdilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate. |
| AID340736 | Activity of Chryseobacterium indologenes metallo-beta-lactamase IND-5 expressed in Escherichia coli BL21(DE3) assessed as substrate hydrolysis | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Identification and characterization of a new metallo-beta-lactamase, IND-5, from a clinical isolate of Chryseobacterium indologenes. |
| AID1265689 | Antibiofilm activity against Pseudoalteromonas lipolytica TC8 assessed as microbial adhesion at 200 uM after 15 hrs by Syto61 based-fluorescence analysis relative to control | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Click-based synthesis of bromotyrosine alkaloid analogs as potential anti-biofilm leads for SAR studies. |
| AID318714 | Antimicrobial activity against Streptococcus faecium by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID1075970 | Antifungal activity against Candida albicans NCIM 3100 after 72 hrs by broth micro-dilution method | 2014 | European journal of medicinal chemistry, Mar-21, Volume: 75 | Toward new classes of potent antibiotics: synthesis and antimicrobial activity of novel metallosaldach-imidazolium salts. |
| AID543803 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 assessed as eradication of pre-formed biofilm at 1 to 10 times MIC after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID573359 | Antibacterial activity against ceftazidime-susceptible Klebsiella pneumoniae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1769813 | Antimicrobial activity against Enterococcus faecium ATCC 35682 assessed as inhibition of bacterial growth incubated for 16 to 18 hrs by broth micro dilution technique | |||
| AID395738 | Antimicrobial activity against Haemophilus influenzae Rd transformed with ftsI gene from imipenem-resistant invasive nontypeable Haemophilus influenzae isolate 183 by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | First characterization of heterogeneous resistance to imipenem in invasive nontypeable Haemophilus influenzae isolates. |
| AID420203 | Antimicrobial activity against Bacillus subtilis UFPEDA 16 at 10 ug/disk after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID564825 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID489647 | Antibacterial activity against Enterobacter cloacae ATCC 49141 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID573392 | Antibacterial activity against ceftazidime-susceptible Providencia sp. assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID585418 | Antimicrobial activity against Escherichia coli C600 by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID465610 | Antibacterial activity against Bacillus subtilis ATCC 6633 | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Discorhabdins from the Korean marine sponge Sceptrella sp. |
| AID530204 | Antimicrobial activity against Mycobacterium bovis BCG ML1061 carrying transposon IS1096::Km inserted at +19bp of lppA gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID529582 | Ratio of Kcat to Km for Bradyrhizobium japonicum beta-Lactamase BJP-1 | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora. |
| AID572054 | Antibacterial activity against Bifidobacterium dentium by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID582916 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61H mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID163253 | Not Plasmodium species | 1986 | Journal of medicinal chemistry, Jun, Volume: 29, Issue:6 | The lysine pathway as a target for a new genera of synthetic antibacterial antibiotics? |
| AID530501 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype IA isolate 6649-05 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID289243 | Antimicrobial activity against Pseudomonas aeruginosa | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18 | Utility of 6-amino-2-thiouracil as a precursor for the synthesis of bioactive pyrimidine derivatives. |
| AID546967 | Antibacterial activity against Aeromonas hydrophila assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID287378 | Antibacterial activity against Listeria monocytogenes after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID573351 | Antibacterial activity against ceftazidime-nonsusceptible Enterobacter cloacae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1281306 | Antibacterial activity against Escherichia coli at 50 mM after 16 to 24 hrs by disk diffusion assay | 2016 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 26, Issue:5 | Synthesis and SAR of 4-methyl-5-pentylbenzene-1,3-diol (MPBD), produced by Dictyostelium discoideum. |
| AID278564 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium longum ATCC 15708 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID333990 | Antibacterial activity against Salmonella typhi at 200 ug/100 uL after 24 hrs by tube broth dilution method | 1997 | Journal of natural products, Oct, Volume: 60, Issue:10 | New steroidal alkaloids from Buxus longifolia. |
| AID421841 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 700787 | 2009 | Journal of natural products, Feb-27, Volume: 72, Issue:2 | Glionitrin A, an antibiotic-antitumor metabolite derived from competitive interaction between abandoned mine microbes. |
| AID420223 | Antimicrobial activity against multidrug-resistant Staphylococcus aureus H.C. 20905 isolate after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID295104 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 10 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID1156857 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus after 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents. |
| AID1769815 | Antimicrobial activity against Bacillus thuringiensis BT01 assessed as inhibition of bacterial growth incubated for 16 to 18 hrs by broth micro dilution technique | |||
| AID1908131 | Antibacterial activity against NDM-1 expressing Klebsiella pneumoniae ATCC BAA 2470 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID743656 | Antibacterial activity against Escherichia coli EB2120 conditional lolA strain with lolA deletion and complementing copy placed at araBAD locus at 1 to 256 ug/mL after 18 hrs in presence of 0.00002 to 0.2% of arabinose | 2013 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 23, Issue:8 | Degradation of MAC13243 and studies of the interaction of resulting thiourea compounds with the lipoprotein targeting chaperone LolA. |
| AID369627 | Antimicrobial activity against beta-lactamase negative ampicillin-susceptible Haemophilus influenzae by E-test | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Can the Etest correctly determine the MICs of beta-lactam and cephalosporin antibiotics for beta-lactamase-negative ampicillin-resistant Haemophilus influenzae? |
| AID477749 | Antimicrobial activity against Escherichia coli after 24 hrs | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | An eco-friendly synthesis and antimicrobial activities of dihydro-2H-benzo- and naphtho-1,3-oxazine derivatives. |
| AID112355 | In Vivo evaluation for its effective dose against Haemophilus influenzae (351RD7 AmpR beta (+)) | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID1412924 | Antibacterial activity against Escherichia coli ATCC 35210 by microdilution method | 2018 | MedChemComm, May-01, Volume: 9, Issue:5 | Design, synthesis and antimicrobial activity of usnic acid derivatives. |
| AID324221 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 assessed as cell count in stationary phase at 100 ug/ml after 3 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID573334 | Antibacterial activity against ceftazidime-susceptible Enterobacteriaceae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1585535 | Antibacterial activity against Bacillus subtilis assessed as zone of inhibition at 50 ug/ml after 3 days by filter paper disc method | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Benzofuran derivatives and their anti-tubercular, anti-bacterial activities. |
| AID546945 | Antibacterial activity against Salmonella enterica serovar Heidelberg by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID573339 | Antibacterial activity against ceftazidime-nonsusceptible Enterobacteriaceae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID278546 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium bifidum R0071 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID735981 | Antimicrobial activity against Pseudomonas aeruginosa at 1 mg/mL after 24 hrs by agar disc diffusion method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Synthesis and antimicrobial activity of some new benzo and naphthonitrile derivatives. |
| AID85785 | In vitro inhibitory activity against Haemophilus AmpS (43) | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID544028 | Antimicrobial activity against Acinetobacter lwoffii isolate C141 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID567773 | Antimicrobial activity against Bacillus cereus ATCC 10876 assessed as >99.9 % reduction in CFU after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID1114823 | Antibacterial activity against Escherichia coli ATCC 25922 after 18 to 24 hr by double microdilution method | 2013 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, Aug, Volume: 22, Issue:8 | |
| AID424866 | Antibacterial activity against wild type Salmonella enterica serovar Typhimurium ATCC 14028 by modified twofold broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | The PhoQ-activating potential of antimicrobial peptides contributes to antimicrobial efficacy and is predictive of the induction of bacterial resistance. |
| AID572242 | Antibacterial activity against Peptostreptococcus anaerobius by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID565666 | Antimicrobial activity against beta-lactamase positive (amoxicillin)clavulanate-resistant Haemophilus influenzae by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID1290444 | Antibacterial activity against Escherichia coli MTCC 443 after 24 to 48 hrs by broth microdilution method | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities. |
| AID1466811 | Antifungal activity against Candida albicans ATCC 10231 assessed as diameter of inhibition zone after 24 hrs by agar well diffusion method | 2017 | Bioorganic & medicinal chemistry letters, 06-15, Volume: 27, Issue:12 | Synthesis and in vitro biological evaluation of novel coumarin derivatives containing isoxazole moieties on melanin synthesis in B16 cells and inhibition on bacteria. |
| AID529591 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-10 assessed as bacterial density at 1024 ug/ml after 18 hrs | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID524967 | Antibacterial activity against vancomycin- and teichoplanin-nonsusceptible Enterococcus faecalis clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Comparative surveillance study of telavancin activity against recently collected gram-positive clinical isolates from across the United States. |
| AID671469 | Antibacterial activity against Staphylococcus aureus ATCC 12598 after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Aug-01, Volume: 20, Issue:15 | Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. |
| AID534721 | Antimicrobial activity against Parabacteroides goldsteinii by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID572238 | Antibacterial activity against Anaerococcus prevotii by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID425652 | Total body clearance in human | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15 | Physicochemical determinants of human renal clearance. |
| AID546942 | Antibacterial activity against Salmonella enterica serovar Virchow by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID562386 | Antimicrobial activity against Enterococcus faecalis expressing VanA gene clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1596671 | Bactericidal activity against Micrococcus flavus ATCC 10240 incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID255540 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 1.0 uM/ml in dimethylformamide, + = resistant | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID564811 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1504234 | Antibacterial activity against Enterococcus faecium ATCC 19434 after 24 hrs by two fold serial dilution method | 2017 | Journal of natural products, 11-22, Volume: 80, Issue:11 | Nicrophorusamides A and B, Antibacterial Chlorinated Cyclic Peptides from a Gut Bacterium of the Carrion Beetle Nicrophorus concolor. |
| AID623611 | Antibacterial activity against 10'8 CFU/mL Bacillus subtilis MTCC 441 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID287235 | Antimicrobial activity against Bacillus subtilis IFO 3007 at 100 ug/disc after 24 hrs | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles. |
| AID535241 | Antimicrobial activity against Bifidobacterium pseudocatenulatum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID405315 | Antibacterial activity against Haemophilus influenzae group IIb isolates with ftsI gene mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID585675 | Antimicrobial activity against ampG, ampGh1 deficient Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1079931 | Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum activity 6 times the normal upper limit (N) or alkaline phosphatase serum activity of 1.7 N. Value is number of references indexed. [column 'BIOL' in source] | |||
| AID547188 | Antibacterial activity against Vibrio sp. by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID648407 | Antibacterial activity against Escherichia coli ATTC 25922 at MIC after 3 to 4 days by disc diffusion method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Facile synthesis, characterization and pharmacological activities of 3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 5,6-dihydro-3,6-disubstituted-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles. |
| AID590508 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs | 2011 | European journal of medicinal chemistry, Apr, Volume: 46, Issue:4 | Synthesis, biopharmaceutical characterization, antimicrobial and antioxidant activities of 1-(4'-O-β-D-glucopyranosyloxy-2'-hydroxyphenyl)-3-aryl-propane-1,3-diones. |
| AID614152 | Antimicrobial activity against Bacillus subtilis ATCC 6633 | 2011 | Journal of natural products, Aug-26, Volume: 74, Issue:8 | Sesterterpenes from the tropical sponge Coscinoderma sp. |
| AID1060494 | Antibacterial activity against Klebsiella pneumoniae MTCC 109 by agar streak dilution method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Access to a new class of biologically active quinoline based 1,2,4-triazoles. |
| AID510157 | Antimicrobial activity against cephalosporin-resistant Acinetobacter baumannii by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID555253 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 67 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID340738 | Ratio of Kcat to Km of Chryseobacterium indologenes metallo-beta-lactamase IND-5 expressed in Escherichia coli BL21(DE3) assessed as substrate hydrolysis relative to control | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Identification and characterization of a new metallo-beta-lactamase, IND-5, from a clinical isolate of Chryseobacterium indologenes. |
| AID371353 | Antibacterial activity against Micrococcus luteus IFC 12708 after 24 hrs | 2009 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 19, Issue:3 | Synthesis and antimicrobial activities of halogenated bis(hydroxyphenyl)methanes. |
| AID1700383 | Antibacterial activity against Salmonella enterica subsp.enterica NCTC 13349 assessed as reduction in microbial growth after 18 hrs by agar dilution method | 2020 | Journal of natural products, 11-25, Volume: 83, Issue:11 | Total Syntheses of Prenylated Isoflavones from |
| AID289314 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18 | Synthesis and antimicrobial activity of some new thiazolyl thiazolidine-2,4-dione derivatives. |
| AID567761 | Antimicrobial activity against Staphylococcus aureus ATCC 6538 after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID558002 | Antimicrobial activity in Clostridium clostridioforme by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID534729 | Antimicrobial activity against Bacteroides nordii by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID546970 | Antibacterial activity against Aeromonas caviae assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID632565 | Antifungal activity against Candida albicans at 200 ug/mL after 48 hrs by agar cup diffusion assay | 2011 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 21, Issue:24 | A new antifungal briarane diterpenoid from the gorgonian Junceella juncea Pallas. |
| AID574173 | Antibacterial activity against Escherichia coli OCL62 harboring plasmid pBR322 carrying blaTEM-1 and tetA(C) genes grown as planktonic cells after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID1132046 | Antibacterial activity against Staphylococcus aureus Russel | 1978 | Journal of medicinal chemistry, Jan, Volume: 21, Issue:1 | Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. |
| AID535746 | Antimicrobial activity against hospital-acquired Klebsiella pneumoniae expressing extended spectrum beta-lactamase obtained from patient with intra-abdominal infection assessed as susceptible isolates by EUCAST method in presence of beta-lactamase inhibit | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Incidence and antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae with extended-spectrum beta-lactamases in community- and hospital-associated intra-abdominal infections in Europe: results of the 2008 Study for Monitoring Antimicrob |
| AID655700 | Antibacterial activity against Staphylococcus aureus ATCC 11632 at 20 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID559332 | Antimicrobial activity against Shigella flexneri harboring oxa-2-like gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID324213 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoU mutant assessed as cell count in stationary phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID601599 | Antibacterial activity against Escherichia coli DH5[alpha] at 10 ug/disk after 24 hrs by disc diffusion assay | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Synthesis of 2-aziridinyl phosphonates by modified Gabriel-Cromwell reaction and their antibacterial activities. |
| AID535641 | Antimicrobial activity against Group B streptococcus serotype V C1 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID545460 | Antimicrobial activity against Serratia marcescens assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID535199 | Antimicrobial activity against Clostridium ramosum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID547189 | Antibacterial activity against Vibrio sp. assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID565504 | Antimicrobial activity against beta-lactamase negative ampicillin-resistant -Haemophilus influenzae by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID1433837 | Antibacterial activity against Bacillus subtilis MTCC 441 after 24 to 48 hrs by broth microdilution method | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs. |
| AID533394 | Antimicrobial activity against Clostridium innocuum by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID555686 | Antimicrobial activity against Escherichia coli ATCC 25922 by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg. |
| AID283322 | Antimicrobial activity against Escherichia coli XL10/pSHV-31 | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Detection of a new SHV-type extended-spectrum beta-lactamase, SHV-31, in a Klebsiella pneumoniae strain causing a large nosocomial outbreak in The Netherlands. |
| AID556757 | Bactericidal activity against katG,katE gene-deficient Escherichia coli K-12 3201 after 18 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID1436939 | Antibacterial activity against Escherichia coli ATCC 25292 after 8 hrs | 2017 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 27, Issue:4 | Quinolidene based monocarbonyl curcumin analogues as promising antimycobacterial agents: Synthesis and molecular docking study. |
| AID548254 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID1243995 | Antimicrobial activity against Escherichia coli by agar dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | Design and synthesis of some new pyrazolyl-pyrazolines as potential anti-inflammatory, analgesic and antibacterial agents. |
| AID456077 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID295116 | Antibacterial activity against Listeria monocytogenes ATCC 15313 at 10 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID436779 | Antibacterial activity against Bacillus cereus ATCC 14579 at 25 ug/mL after 24 hrs by agar diffusion assay | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10 | Synthesis, characterization and in vitro antimicrobial activity of novel 2-thioxo-4-thiazolidinones and 4,4'-bis(2-thioxo-4-thiazolidinone-3-yl)diphenylsulfones. |
| AID590289 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase. |
| AID572240 | Antibacterial activity against Finegoldia magna by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1156856 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents. |
| AID1079948 | Times to onset, minimal and maximal, observed in the indexed observations. [column 'DELAI' in source] | |||
| AID252618 | Mean lysis diameter of wild type Enterobacter aerogenes EA289 with OmpF by standard disk diffusion method on MH agar | 2005 | Journal of medicinal chemistry, Mar-10, Volume: 48, Issue:5 | Beta-lactam screening by specific residues of the OmpF eyelet. |
| AID557692 | Antimicrobial activity in Prevotella bergensis by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID419339 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis and evaluation of some new benzimidazole derivatives as potential antimicrobial agents. |
| AID497691 | Antimicrobial activity against colistin-resistant Klebsiella pneumoniae isolated from bacteremia patient by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea. |
| AID1286508 | Antibacterial activity against vancomycin-resistant Enterococcus after 20 to 24 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID1423482 | Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID405819 | Antimicrobial activity against Acinetobacter sp. 5227 isolate harboring bla IMP-1 carrying integron In86 containing aminoglycoside resistance gene aac(6')-3 | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital. |
| AID324163 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid vector after 16 hrs by serial dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID565744 | Antimicrobial activity against Enterococcus faecium expressing VanA gene clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID682286 | TP_TRANSPORTER: inhibition of Carnitine uptake (Carnitine: 0.02 uM, Ampicillin: 2500 uM) in OCTN2-expressing HeLa cells | 2000 | The Journal of biological chemistry, Jan-21, Volume: 275, Issue:3 | beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter. |
| AID419330 | Antibacterial activity against Bacillus subtilis MTCC 121 at 100 ug/ml after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis and evaluation of some new benzimidazole derivatives as potential antimicrobial agents. |
| AID548029 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237K mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID573348 | Antibacterial activity against ceftazidime-susceptible Enterobacter cloacae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1143592 | Antibacterial activity against Enterococcus assessed as diameter of growth inhibition zone after 24 hrs by two fold serial dilution method | 2014 | European journal of medicinal chemistry, Jun-23, Volume: 81 | Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-arylethanones: antibacterial, DNA photocleavage, and anticancer activities. |
| AID529576 | Ratio of Kcat to Km for Erwinia carotovora subsp. atroseptica DSM 30184 beta-Lactamase CAR-1 | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora. |
| AID568674 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 assessed as growth inhibition at 10 ug/ml by agar dilution method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and structure-activity relationship of 2-thiopyrimidine-4-one analogs as antimicrobial and anticancer agents. |
| AID568829 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 at 25 ug/ml by agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis of 4H-chromene, coumarin, 12H-chromeno[2,3-d]pyrimidine derivatives and some of their antimicrobial and cytotoxicity activities. |
| AID535681 | Antimicrobial activity against beta-lactamase negative Haemophilus influenzae expressing fst1 gene by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Genotypic versus phenotypic characterization, with respect to beta-lactam susceptibility, of Haemophilus influenzae isolates exhibiting decreased susceptibility to beta-lactam resistance markers. |
| AID1382083 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 to 24 hrs by double microdilution method | 2018 | European journal of medicinal chemistry, Feb-25, Volume: 146 | Ciprofloxacin derivatives and their antibacterial activities. |
| AID623614 | Antibacterial activity against 10'8 CFU/mL Salmonella typhi MTCC 98 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID573382 | Antibacterial activity against beta lactamase-positive Haemophilus influenzae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1322101 | Antimicrobial activity against Escherichia coli ATCC 35218 after 24 hrs by broth microdilution assay | 2016 | Bioorganic & medicinal chemistry, 11-01, Volume: 24, Issue:21 | Synthesis, characterization, and evaluation of (E)-methyl 2-((2-oxonaphthalen-1(2H)-ylidene)methylamino)acetate as a biological agent and an anion sensor. |
| AID555243 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 56 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID559335 | Antimicrobial activity against Shigella flexneri harboring shv-like gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID736479 | Antibacterial activity against Staphylococcus epidermidis RCMB 010024 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID558812 | Antimicrobial activity against Proteus mirabilis assessed as percent susceptible isolates by CLSI method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007. |
| AID266673 | Antibacterial activity against Staphylococcus aureus | 2006 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 16, Issue:14 | Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives. |
| AID534725 | Antimicrobial activity against Bacteroides thetaiotaomicron by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID633947 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID463414 | Antimicrobial activity against Salmonella Typhimurium after 24 hrs by liquid dilution method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines. |
| AID494165 | Antibacterial activity against Pseudomonas aeruginosa after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, characterization, in vitro and molecular docking studies of new 2,5-dichloro thienyl substituted thiazole derivatives for antimicrobial properties. |
| AID587960 | Activity of Escherichia coli beta-lactamase Toho-1 A237A mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID1399502 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID322313 | Antibacterial activity against CTX-M group 1 enzyme producing Escherichia coli isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal. |
| AID293857 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 25923 after 24 hrs by two fold dilution method | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6 | Synthesis of pseudopeptides based L-tryptophan as a potential antimicrobial agent. |
| AID1868105 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolate 6B assessed as inhibition of visible bacterial growth incubated for 18 hrs by CLSI protocol based assay | 2022 | Journal of natural products, 05-27, Volume: 85, Issue:5 | Enceleamycins A-C, Furo-Naphthoquinones from |
| AID1372805 | Bactericidal activity against Staphylococcus aureus ATCC 6538 by two-fold serial dilution assay | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2 | An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold. |
| AID565007 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus epidermidis after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID548531 | Antimicrobial activity against Vancomycin-susceptible Enterococcus faecium by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID562590 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecium clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1139545 | Antibacterial activity against Escherichia coli DH5alpha expressing beta-lactamase OXA-24/40 by CLSI broth microdilution method | 2014 | Journal of medicinal chemistry, May-08, Volume: 57, Issue:9 | Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. |
| AID1328384 | Antibacterial activity against Mycobacterium smegmatis after 48 hrs by MTT based microdilution assay | 2016 | Journal of natural products, 09-23, Volume: 79, Issue:9 | Total Synthesis of (±)-Isoperbergins and Correction of the Chemical Structure of Perbergin. |
| AID522364 | Antimicrobial activity against PpmrI knockout mutant Proteus mirabilis dIp after 16 to 18 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Proteus mirabilis pmrI, an RppA-regulated gene necessary for polymyxin B resistance, biofilm formation, and urothelial cell invasion. |
| AID324307 | Antibacterial activity against Escherichia coli K12 containing deletion deltahipA mutant assessed as cell count in stationary phase at 100 ug/ml after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID520389 | Ratio of Kcat to Km for Pseudomonas aeruginosa COL-1 metallo-beta lactamase VIM-2 over Kcat to Km for Pseudomonas aeruginosa M5109 metallo-beta-lactamase VIM-11 | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain. |
| AID548532 | Antimicrobial activity against Vancomycin-nonsusceptible Enterococcus faecium by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID528697 | Antibacterial activity against vancomycin resistant Enterococcus faecium VanB clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID386971 | Antimicrobial activity Fusarium oxysporum at 25 ug/mL after 48 hrs by agar diffusion technique | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10 | Synthesis and antimicrobial activity of some new heterocycles incorporating antipyrine moiety. |
| AID574177 | Antibacterial activity against Escherichia coli MG1655 grown as planktonic cells harboring plasmid pBR322 carrying blaTEM-1 and tetA(C) genes assessed as reduction in bacterial biofilms formation | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID723715 | Bactericidal activity against Listeria monocytogenes NCTC 7973 after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID565683 | Antimicrobial activity against beta-lactamase-positive ampicillin-resistant Haemophilus influenzae harboring fst1 mutant gene by broth microdilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID565505 | Antimicrobial activity against beta-lactamase negative ampicillin-resistant Haemophilus influenzae by broth microdilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID1545443 | Antibacterial activity against Bacillus subtilis assessed as zone inhibition at 500 ug/ml by cup plate agar diffusion method | 2019 | Bioorganic & medicinal chemistry, 04-01, Volume: 27, Issue:7 | Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances. |
| AID523274 | Activity at Escherichia coli isolate 7181 beta-lactamase OXA-7 measured per mg of protein | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Kinetic parameters of efflux of penicillins by the multidrug efflux transporter AcrAB-TolC of Escherichia coli. |
| AID551092 | Antibacterial activity against Bacillus subtilis by liquid dilution method | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1 | 3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents. |
| AID601334 | Antibacterial activity against Staphylococcus aureus Col CGMCC 1.2465 after 24 hrs by NCCLS M27-A2 method | 2011 | Journal of natural products, May-27, Volume: 74, Issue:5 | Verrucamides A-D, antibacterial cyclopeptides from Myrothecium verrucaria. |
| AID735976 | Antimicrobial activity against Escherichia coli after 24 hrs by microdilution susceptibility test | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Synthesis and antimicrobial activity of some new benzo and naphthonitrile derivatives. |
| AID429264 | Antibacterial activity against Bacillus subtilis at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents. |
| AID556754 | Bactericidal activity against sodA, sodB gene-deficient Escherichia coli K-12 3156 after 18 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID572251 | Antibacterial activity against Bacteroides thetaiotaomicron by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1337844 | Antifungal activity against Aspergillus flavus NCIM 539 by standard agar method | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Quinolidene-rhodanine conjugates: Facile synthesis and biological evaluation. |
| AID1104308 | Antibacterial activity against Listeria monocytogenes NCTC 7973 at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID533364 | Antimicrobial activity against Bacteroides thetaiotaomicron assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID572228 | Antibacterial activity against Holdemania filiformis by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID524971 | Antibacterial activity against vancomycin-resistant and teichoplanin-susceptible Enterococcus faecium clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Comparative surveillance study of telavancin activity against recently collected gram-positive clinical isolates from across the United States. |
| AID324977 | Antibacterial activity against Haemophilus influenzae MSC01869 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID395737 | Antimicrobial activity against imipenem-susceptible Haemophilus influenzae Rd by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | First characterization of heterogeneous resistance to imipenem in invasive nontypeable Haemophilus influenzae isolates. |
| AID285523 | Antibacterial activity against Moraxella catarrhalis after 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens. |
| AID530518 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype V isolate 4857-03 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID584477 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN07 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID534989 | Antimicrobial activity against Clostridium beijerinckii by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1224736 | Antimicrobial activity against Streptococcus pneumoniae MTCC 1936 by broth microdilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Ultrasound-assisted one-pot four-component synthesis of novel 2-amino-3-cyanopyridine derivatives bearing 5-imidazopyrazole scaffold and their biological broadcast. |
| AID1728306 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as diameter of inhibition zone at 10 mg/ml by disk diffusion assay | 2021 | European journal of medicinal chemistry, Jan-15, Volume: 210 | Preparation of new 1,3-dibenzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. |
| AID585845 | Antimicrobial activity against Pseudomonas aeruginosa isolate 3 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID389007 | Antibacterial activity against Staphylococcus aureus ATCC 6538 by dilution assay | 2008 | Bioorganic & medicinal chemistry, Dec-01, Volume: 16, Issue:23 | Hetero-Diels-Alder reaction of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with arylsulfonylcyanides. Synthesis and antimicrobial activity of 4-hydroxy-2-(arylsulfonyl)pyridines. |
| AID530207 | Antimicrobial activity against Mycobacterium bovis BCG ML1036 carrying transposon IS1096::Km inserted at +277bp of agpS gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1359444 | Antibacterial activity against Pseudomonas aeruginosa NCIM 2036 after 8 hrs by serial dilution method | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Antibacterial and anti-TB tat-peptidomimetics with improved efficacy and half-life. |
| AID545660 | Antimicrobial activity against Acinetobacter sp. assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID555248 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 60 by Etest method in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID534949 | Antimicrobial activity against Fusobacterium sp. by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID495334 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with Asp350Asn, Ser357Asp, Met377Ile, Ser385Thr, Ala502Thr, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID496397 | Antibacterial activity against azide-resistant Escherichia coli J53 SXT2 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID603038 | Antimicrobial activity against Bacillus subtilis at 1 ug/mL after 48 hrs by cup plate agar diffusion method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | Synthesis, antitumor and antimicrobial activities of 4-(4-chlorophenyl)-3-cyano-2-(β-O-glycosyloxy)-6-(thien-2-yl)-nicotinonitrile. |
| AID1545446 | Antibacterial activity against Pseudomonas aeruginosa assessed as zone inhibition at 500 ug/ml by cup plate agar diffusion method | 2019 | Bioorganic & medicinal chemistry, 04-01, Volume: 27, Issue:7 | Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances. |
| AID324170 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid PhoU at 25 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID732564 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs | 2013 | Journal of natural products, Jan-25, Volume: 76, Issue:1 | Arundinols A-C and arundinones A and B from the plant endophytic fungus Microsphaeropsis arundinis. |
| AID355422 | Antibacterial activity against Escherichia coli ATCC 25922 after 18 hrs by broth microdilution method | 2003 | Journal of natural products, Dec, Volume: 66, Issue:12 | New triterpene glycosides from the stems of Anomospermum grandifolium. |
| AID583098 | Antimicrobial activity against Escherichia coli XL1-Blue harboring pLBII-VIM-2 plasmid expressing VIM-2 beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID717347 | Antimicrobial activity against Proteus hauseri NBRC 3851 after 24 hrs | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12 | Brominated aromatic furanones and related esters from the ascidian Synoicum sp. |
| AID574176 | Antibacterial activity against Escherichia coli MG1655 grown as biofilms harboring plasmid pBR322 carrying blaTEM-1 and tetA(C) genes assessed as reduction in bacterial biofilms formation | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID573367 | Antibacterial activity against ceftazidime-susceptible Proteus mirabilis by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID678541 | Antibacterial activity against Staphylococcus aureus ATCC 25923 | 2012 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 22, Issue:18 | Design, solvent free synthesis, and antimicrobial evaluation of 1,4 dihydropyridines. |
| AID1287099 | Antimicrobial activity against Candida albicans ATCC 2002 assessed as inhibition of bacterial growth after 16 hrs by broth dilution method | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis. |
| AID585424 | Antimicrobial activity against oqxAB positive Escherichia coli C600 G062-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID556753 | Bactericidal activity against sodB gene-deficient Escherichia coli K-12 3145 after 18 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID365670 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by twofold serial dilution method | 2008 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 18, Issue:16 | Substituted 3-((Z)-2-(4-nitrophenyl)-2-(1H-tetrazol-5-yl) vinyl)-4H-chromen-4-ones as novel anti-MRSA agents: synthesis, SAR, and in-vitro assessment. |
| AID1499659 | Antimicrobial activity against Streptococcus pneumoniae RCMB 010010 after 24 hrs by serial dilution method | 2017 | European journal of medicinal chemistry, Sep-29, Volume: 138 | Design, synthesis and 2D QSAR study of novel pyridine and quinolone hydrazone derivatives as potential antimicrobial and antitubercular agents. |
| AID1546114 | Antifungal activity against Candida albicans | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID426130 | Antimicrobial activity against Candida tropicalis ATCC 13803 at 5 ug after 18 hrs by agar-well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities. |
| AID530429 | Resistance factor, ratio of MIC for Mycobacterium smegmatis overexpressing rv0194 gene to MIC for wild-type Mycobacterium smegmatis SMR5 | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1769814 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 assessed as inhibition of bacterial growth incubated for 16 to 18 hrs by broth micro dilution technique | |||
| AID1693219 | Anti-infective activity against Escherichia coli ATCC 35210 assessed as reduction in bacterial growth by microdilution method | 2021 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 32 | 2-Aryl-3-(6-trifluoromethoxy)benzo[d]thiazole-based thiazolidinone hybrids as potential anti-infective agents: Synthesis, biological evaluation and molecular docking studies. |
| AID529829 | Antimicrobial activity against Acinetobacter baumannii by microdilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | In vitro activity of tigecycline against multidrug-resistant Acinetobacter baumannii and selection of tigecycline-amikacin synergy. |
| AID1585534 | Antibacterial activity against Staphylococcus aureus assessed as zone of inhibition at 50 ug/ml after 3 days by filter paper disc method | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Benzofuran derivatives and their anti-tubercular, anti-bacterial activities. |
| AID588212 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID625283 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID776459 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 at 10 ug | 2013 | European journal of medicinal chemistry, Nov, Volume: 69 | Design, synthesis and biological activities of some 7-aminocephalosporanic acid derivatives. |
| AID1419477 | Antimicrobial activity against Staphylococcus aureus by two fold serial dilution method | 2017 | European journal of medicinal chemistry, May-05, Volume: 131 | Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents. |
| AID543798 | Antimicrobial activity against Streptococcus pyogenes VT 59 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID318661 | Antibacterial activity against Peptostreptococcus anaerobius GAI 5506 by broth microdilution method | 2008 | Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7 | Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens. |
| AID519659 | Antimicrobial activity against Escherichia coli EPI300 Irk1224 type 3 mutant harboring CTX-M-3 beta-lactamase Lys136 mutant gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID495346 | Antimicrobial activity against Beta-lactamase-positive, ampicillin-cluvulanate-resistant Haemophilus influenzae with Asp350Asn, Ser357Asp, Ala437Ser, Ala502Thr, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID564821 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus hominis after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID558337 | Antibacterial activity against bla gene-positive and nitrocefin reaction-positive beta-lactamase harboring Campylobacter jejuni isolate P1650 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID295098 | Antibacterial activity against Staphylococcus aureus ATCC 6538 at 10 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID567768 | Antimicrobial activity against Proteus mirabilis ATCC 12453 after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID1286490 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 6538 after 20 to 24 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID519009 | Ratio of Kcat to Km for Beta-lactamase TEM-149 expressed in Escherichia coli HB101 | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | E240V substitution increases catalytic efficiency toward ceftazidime in a new natural TEM-type extended-spectrum beta-lactamase, TEM-149, from Enterobacter aerogenes and Serratia marcescens clinical isolates. |
| AID548483 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSn mutant gene after 48 hrs by Etest in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID640493 | Antibacterial activity against Staphylococcus aureus ATCC 6538p | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2 | Bioactive lipids from the sponge Spirastrella abata. |
| AID373681 | Antibacterial activity against Klebsiella pneumoniae NCIMB 9111 after 24 hrs by broth microdilution method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID535225 | Antimicrobial activity against Actinomyces viscosus by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID533134 | Antimicrobial activity against Bacteroides fragilis assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID238858 | Binding affinity against membrane transport protein PEPT1 in human Caco-2 cells | 2005 | Journal of medicinal chemistry, Jun-30, Volume: 48, Issue:13 | Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1. |
| AID520716 | Antibacterial activity against Acinetobacter baumannii CIP7010 by disk diffusion method in presence of 4 ug/ml clavulanic acid | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID1491081 | Antibacterial activity against Proteus hauseri NBRC 3851 after 24 hrs by serial two fold dilution method | 2017 | Journal of natural products, 05-26, Volume: 80, Issue:5 | Manzamine Alkaloids from an Acanthostrongylophora sp. Sponge. |
| AID1657538 | Antibacterial activity against Listeria monocytogenes MB677 assessed as reduction in microbial growth after 20 hrs by microdilution method | 2020 | Journal of natural products, 05-22, Volume: 83, Issue:5 | Genomics-Metabolomics Profiling Disclosed Marine |
| AID530505 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype II isolate 3776-04 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID543411 | Antimicrobial activity against Shigella sonnei UIH-1 expressing beta-lactamase CTX-M-64 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime. |
| AID657437 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis after 16 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9 | Preparation, antibacterial evaluation and preliminary structure-activity relationship (SAR) study of benzothiazol- and benzoxazol-2-amine derivatives. |
| AID555445 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 195 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID717348 | Antimicrobial activity against Salmonella enterica ATCC 14028 after 24 hrs | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12 | Brominated aromatic furanones and related esters from the ascidian Synoicum sp. |
| AID533638 | Antimicrobial activity against Propionibacterium sp. assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID587970 | Ratio of Kcat to Km for Escherichia coli beta-lactamase Toho-1 N104D mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID534965 | Antimicrobial activity against Prevotella intermedia by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1730945 | Antibacterial activity against Staphylococcus aureus MTCC 96 assessed as bacterial growth inhibition | 2021 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 36 | Structure based design, synthesis, and biological evaluation of imidazole derivatives targeting dihydropteroate synthase enzyme. |
| AID736481 | Antibacterial activity against Proteus vulgaris RCMB 010085 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID1551812 | Antibacterial activity against Bacillus anthracis incubated for 18 hrs post 30 mins pre-diffusion by disk diffusion method | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID1419475 | Antimicrobial activity against Escherichia coli by two fold serial dilution method | 2017 | European journal of medicinal chemistry, May-05, Volume: 131 | Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents. |
| AID64748 | Influence of siderophore receptor on antibacterial activity in Escherichia coli (H1876) using agar diffusion assay | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID572043 | Antibacterial activity against Clostridium scindens by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID405302 | Antibacterial activity against beta-lactamase positive ampicillin resistant Haemophilus influenzae isolate by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID373669 | Antibacterial activity against Bacillus subtilis ATCC 6633 at 10 ug/disk after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID535431 | Antimicrobial activity against Eubacterium callanderi by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID285521 | Antibacterial activity against Pseudomonas aeruginosa after 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens. |
| AID541023 | Ratio of Kcat to Km for Burkholderia cenocepacia 07-34 beta-lactamase PenB1 expressed in Escherichia coli Top10 | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Naturally occurring Class A ss-lactamases from the Burkholderia cepacia complex. |
| AID1769957 | Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC49025 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID548530 | Antimicrobial activity against Vancomycin-nonsusceptible Enterococcus faecalis by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID572267 | Antibacterial activity against Prevotella oris by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1126671 | Antibacterial activity against Vibrio cholerae MTCC 3906 assessed as growth inhibition after 24 to 48 hrs by broth microdilution method | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Synthesis, characterization and pharmacological screening of some novel 5-imidazopyrazole incorporated polyhydroquinoline derivatives. |
| AID1287100 | Antimicrobial activity against Bacillus subtilis assessed as inhibition of bacterial growth after 16 hrs by broth dilution method | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis. |
| AID563972 | Activity of Klebsiella pneumoniae 05-560 beta-lactamase NDM-1 by spectrophotometry | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. |
| AID1868109 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 assessed as inhibition of visible bacterial growth incubated for 18 hrs by CLSI protocol based assay | 2022 | Journal of natural products, 05-27, Volume: 85, Issue:5 | Enceleamycins A-C, Furo-Naphthoquinones from |
| AID1071719 | Antimicrobial activity against Bacillus subtilis at 250 ug/disc after 48 hrs by well diffusion method | 2014 | European journal of medicinal chemistry, Mar-03, Volume: 74 | Synthesis and biological evaluation of 2-oxonicotinonitriles and 2-oxonicotinonitrile based nucleoside analogues. |
| AID572239 | Antibacterial activity against Anaerococcus tetradius by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID495337 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with Asp350Asn, Ser357Asp, Met377Ile, Ser385Thr, Leu389Phe, substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID536635 | Antimicrobial activity against Staphylococcus aureus NCTC 7447 by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis of new pyrrolo[2,3-d]pyrimidine derivatives as antibacterial and antifungal agents. |
| AID1143588 | Antibacterial activity against Pseudomonas aeruginosa assessed as diameter of growth inhibition zone after 24 hrs by two fold serial dilution method | 2014 | European journal of medicinal chemistry, Jun-23, Volume: 81 | Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-arylethanones: antibacterial, DNA photocleavage, and anticancer activities. |
| AID564831 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus sciuri assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID478778 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5 | Synthesis, spectroscopic and biological studies on the new symmetric Schiff base derived from 2,6-diformyl-4-methylphenol with N-aminopyrimidine. |
| AID532983 | Antibacterial activity against Escherichia coli W3110 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID609458 | Antibacterial activity against Escherichia coli after 24 hrs by broth dilution method | 2011 | Bioorganic & medicinal chemistry, Aug-01, Volume: 19, Issue:15 | Synthesis of some new [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4] thiadiazoles starting from 5-nitro-2-furoic acid and evaluation of their antimicrobial activity. |
| AID396026 | Antibacterial activity against drug-resistant Enterobacter cloacae EcDC64 isolate expressing AcrAB-TolC efflux pump by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID536237 | Antimicrobial activity against Streptococcus pyogenes MTCC 443 after 24 hrs by serial dilution method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Design, synthesis and in vitro evaluation of antitubercular and antimicrobial activity of some novel pyranopyrimidines. |
| AID405310 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae isolate assessed as percent resistant isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID528698 | Antibacterial activity against vancomycin resistant Enterococcus faecium VanA clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID535209 | Antimicrobial activity against Clostridium sp. by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID583085 | Activity of Escherichia coli BL21(DE3) wild-type VIM-2 beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID530213 | Antimicrobial activity against Mycobacterium bovis BCG ML1009 carrying transposon IS1096::Km inserted at +368bp of cyp121 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID324216 | Antibacterial activity against Escherichia coli K12 containing PhoU mutant assessed as cell count in log phase at 100 ug/ml after 1 day | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1164947 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 at >200 ug/ml by microbroth dilution method | 2014 | Journal of medicinal chemistry, Oct-23, Volume: 57, Issue:20 | Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives. |
| AID521323 | Antimicrobial activity against rifampin-resistant Haemophilus influenzae Rd clone by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Comparison of the efficacies of oral beta-lactams in selection of Haemophilus influenzae transformants with mutated ftsI genes. |
| AID548041 | Antimicrobial activity against Escherichia coli DH10B harboring plasmid pBK SK(+) by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID1228010 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 assessed as complete prevention of visible growth after incubation at 37 degC for 18 to 20 hrs | 2015 | Journal of natural products, Apr-24, Volume: 78, Issue:4 | Antibacterial Biphenanthrenes from the Fibrous Roots of Bletilla striata. |
| AID1185314 | Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis and 3D-QSAR studies of new diphenylamine containing 1,2,4-triazoles as potential antitubercular agents. |
| AID244834 | Minimal inhibitory concentration against Bacillus subtilis | 2004 | Bioorganic & medicinal chemistry letters, Dec-06, Volume: 14, Issue:23 | Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: a structure-activity evaluation study. |
| AID564806 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID564889 | Antibacterial activity against ompF-deficient Escherichia coli AG100 harboring IS186 insertion in lon3 gene and Tn5 insertion in ycgE gene at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID294186 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by macro-broth dilution assay | 2007 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 17, Issue:8 | Synthesis and antimicrobial activity of some novel phenyl and benzimidazole substituted benzyl ethers. |
| AID529623 | Antibacterial activity against Beta-lactamase negative Haemophilus influenzae harboring fst1 mutant gene assessed as resistant isolates after 20 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID548010 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237Q mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID1916813 | Antibacterial activity against Escherichia coli NCIM 2688 assessed as bacterial growth inhibition incubated for 8 hrs by absorbance based assay | 2022 | European journal of medicinal chemistry, Aug-05, Volume: 238 | Recent contribution of medicinally active 2-aminothiophenes: A privileged scaffold for drug discovery. |
| AID588211 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID293860 | Antibacterial activity against methicillin-resistant Staphylococcus aureus CMAH 0504 after 24 hrs by two fold dilution method | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6 | Synthesis of pseudopeptides based L-tryptophan as a potential antimicrobial agent. |
| AID1359443 | Antibacterial activity against Escherichia coli NCIM 2688 after 8 hrs by serial dilution method | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Antibacterial and anti-TB tat-peptidomimetics with improved efficacy and half-life. |
| AID405331 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae group IIc isolates with acrR TTA>TGA mutation at 425 position by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID557990 | Antimicrobial activity in Clostridium innocuum by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID693578 | Antibacterial activity against Pseudomonas aeruginosa MTCC 424 after 24 hrs by tube dilution method | 2012 | European journal of medicinal chemistry, Dec, Volume: 58 | Synthesis pharmacological evaluation and docking studies of pyrimidine derivatives. |
| AID584476 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN06 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID655623 | Antibacterial activity against Burkholderia pseudomallei NTCC 10274 at 20 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID1491080 | Antibacterial activity against Salmonella enterica ATCC 14028 after 24 hrs by serial two fold dilution method | 2017 | Journal of natural products, 05-26, Volume: 80, Issue:5 | Manzamine Alkaloids from an Acanthostrongylophora sp. Sponge. |
| AID549013 | Antimicrobial activity against Vancomycin-nonsusceptible Enterococcus faecium assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID425583 | Antibacterial activity against Escherichia coli isolate HM605 isolated from colonic mucosal biopsies of patient with Crohn's disease | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID495753 | Antimicrobial activity against Escherichia coli J5 transconjugants expressing beta lactamase CTX-M-9 isolated from human flora associated C3H rat infected with Salmonella enterica serotype Virchow and treated with Cefixime-cluvulanic acid by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID534098 | Antibacterial activity against Acinetobacter baumannii PFGE type A isolate by microdilution method in presence of Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | A plasmid-borne blaOXA-58 gene confers imipenem resistance to Acinetobacter baumannii isolates from a Lebanese hospital. |
| AID1176791 | Inhibition of biofilm formation in Staphylococcus aureus AH133 transformed with GFP assessed as zone of inhibition at 16 mg/ml after 24 hrs by confocal laser scanning microscopy | 2015 | Journal of natural products, Jan-23, Volume: 78, Issue:1 | Teucrium polium phenylethanol and iridoid glycoside characterization and flavonoid inhibition of biofilm-forming Staphylococcus aureus. |
| AID1183259 | Antimicrobial activity against Salmonella typhi MTCC 98 assessed as absence of visible growth after 24 to 48 hrs by broth micro dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis and characterization of fluoro substituted novel pyrazolylpyrazolines scaffold and their pharmacological screening. |
| AID395355 | Antibacterial activity against Mycobacterium smegmatis CCM 2067 at 1 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID535479 | Antimicrobial activity against Ruminococcus flavefaciens by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID533378 | Antimicrobial activity against Bacteroides merdae by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID572050 | Antibacterial activity against Actinomyces naeslundii by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID534084 | Antibacterial activity against erythromycin-resistant Streptococcus pneumoniae isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro activity of ceftaroline against Streptococcus pneumoniae isolates exhibiting resistance to penicillin, amoxicillin, and cefotaxime. |
| AID565011 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID278548 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium bifidum BB12 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID587964 | Activity of Escherichia coli beta-lactamase Toho-1 D240A mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID1471039 | Growth inhibition of Staphylococcus aureus NCIM 2602 at 30 ug/ml measured after 12 hrs relative to control | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID487475 | Antibacterial activity against Escherichia coli NCIM 2065; ATCC 8739 at 100 mg/ml after 24 hrs by agar cup plate method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Design, synthesis, characterization, and antibacterial activity of {5-chloro-2-[(3-substitutedphenyl-1,2,4-oxadiazol-5-yl)-methoxy]-phenyl}-(phenyl)-methanones. |
| AID547176 | Antibacterial activity against Vibrio parahaemolyticus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID585837 | Antimicrobial activity against ampD, ampDh2, ampDh3 and ampG deficient Pseudomonas aeruginosa PAO1 harboring pZY0901 conferring resistance to gentamycin after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID487477 | Antibacterial activity against Bacillus subtilis NCIM 2063; ATCC 6633 after 24 hrs by microtitration method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Design, synthesis, characterization, and antibacterial activity of {5-chloro-2-[(3-substitutedphenyl-1,2,4-oxadiazol-5-yl)-methoxy]-phenyl}-(phenyl)-methanones. |
| AID529194 | Antibacterial activity against AmpC-producing Escherichia coli isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Comparison of antimicrobial resistance profiles among extended-spectrum-beta-lactamase-producing and acquired AmpC beta-lactamase-producing Escherichia coli isolates from Canadian intensive care units. |
| AID584473 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN03 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID660264 | Ratio of MIC for wild type Escherichia coli HS414 to MIC for acrB-deficient Escherichia coli HS832 by agar dilution method | 2012 | European journal of medicinal chemistry, Jun, Volume: 52 | Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics. |
| AID279564 | Antimicrobial activity against Haemophilus influenzae BLPACR strains | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Diversity of ampicillin resistance genes and antimicrobial susceptibility patterns in Haemophilus influenzae strains isolated in Korea. |
| AID555257 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 69 by Etest method in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID255542 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 4.0 uM/ml in dimethylformamide, + = resistant | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID1504235 | Antibacterial activity against Salmonella enterica ATCC 14028 after 24 hrs by two fold serial dilution method | 2017 | Journal of natural products, 11-22, Volume: 80, Issue:11 | Nicrophorusamides A and B, Antibacterial Chlorinated Cyclic Peptides from a Gut Bacterium of the Carrion Beetle Nicrophorus concolor. |
| AID1399257 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus NRS70 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID436288 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by twofold dilution method | 2008 | Journal of natural products, Nov, Volume: 71, Issue:11 | Scalarane sesterterpenes from the sponge Smenospongia sp. |
| AID1320835 | Activity of native signal containing Klebsiella pneumoniae OXA-48 by Michaelis-Menten kinetics assay | 2016 | Journal of medicinal chemistry, 06-09, Volume: 59, Issue:11 | Screening and Design of Inhibitor Scaffolds for the Antibiotic Resistance Oxacillinase-48 (OXA-48) through Surface Plasmon Resonance Screening. |
| AID293876 | Antifungal activity against Candida albicans CMAH 0501 after 48 to 72 hrs by broth microdilution method | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6 | Synthesis of pseudopeptides based L-tryptophan as a potential antimicrobial agent. |
| AID487473 | Antibacterial activity against Bacillus subtilis NCIM 2063; ATCC 6633 at 100 mg/ml after 24 hrs by agar cup plate method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Design, synthesis, characterization, and antibacterial activity of {5-chloro-2-[(3-substitutedphenyl-1,2,4-oxadiazol-5-yl)-methoxy]-phenyl}-(phenyl)-methanones. |
| AID572226 | Antibacterial activity against Coriobacteriumecies by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1071718 | Antimicrobial activity against Escherichia coli at 250 ug/disc after 48 hrs by well diffusion method | 2014 | European journal of medicinal chemistry, Mar-03, Volume: 74 | Synthesis and biological evaluation of 2-oxonicotinonitriles and 2-oxonicotinonitrile based nucleoside analogues. |
| AID444051 | Total clearance in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID557732 | Antimicrobial activity in Micromonas micros by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1868099 | Antibacterial activity against Bacillus cereus ATCC 11778 assessed as inhibition of visible bacterial growth incubated for 18 hrs by CLSI protocol based assay | 2022 | Journal of natural products, 05-27, Volume: 85, Issue:5 | Enceleamycins A-C, Furo-Naphthoquinones from |
| AID324167 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid vector at 100 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1163975 | Antibacterial activity against Staphylococcus aureus KCTC-1916 after 24 hrs by twofold dilution method | 2014 | European journal of medicinal chemistry, Oct-30, Volume: 86 | Anti-tyrosinase, antioxidant, and antibacterial activities of novel 5-hydroxy-4-acetyl-2,3-dihydronaphtho[1,2-b]furans. |
| AID471909 | Antibacterial activity against Escherichia coli MTCC 41 at 64 ug/ml after 16 hrs by disc diffusion method | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | A facile one-pot green synthesis and antibacterial activity of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes. |
| AID519123 | Antibacterial activity against Proteus mirabilis M 35 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID565454 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 planktonic cells assessed as bacterial count at 0.06 ug/ml (Rvb =771.7 +/- 35.14 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID442429 | Antimicrobial activity against Enterobacter cloacae after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID555447 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 243 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID534983 | Antimicrobial activity against Clostridium acetobutylicum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1698867 | Antimicrobial activity against Staphylococcus epidermidis ATCC 14990 assessed as zone of inhibition at 2 mg/ml after 24 hrs by agar well diffusion method | 2020 | Journal of natural products, 10-23, Volume: 83, Issue:10 | Synthesis of Natural and Unnatural Quinolones Inhibiting the Growth and Motility of Bacteria. |
| AID289621 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by micro-broth dilution technique | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, in vitro antibacterial and antifungal evaluations of 2-amino-4-(1-naphthyl)-6-arylpyrimidines. |
| AID420205 | Antimicrobial activity against Enterococcus faecalis UFPEDA 138 at 10 ug/disk after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID496592 | Antimicrobial activity against Escherichia coli DH10B by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase. |
| AID585676 | Antimicrobial activity against ampG deficient Pseudomonas aeruginosa PAO1 harboring pUCP24 conferring resistance to gentamycin after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID781326 | pKa (acid-base dissociation constant) as determined by Avdeef ref: DOI: 10.1002/047145026X | 2014 | Pharmaceutical research, Apr, Volume: 31, Issue:4 | Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. |
| AID584469 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus vitulinus SVMP05 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID330987 | Antimicrobial activity against Enterococcus faecalis 29212 | 2007 | Nature, May-03, Volume: 447, Issue:7140 | PTC124 targets genetic disorders caused by nonsense mutations. |
| AID255536 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 2.0 uM/ml in dimethylformamide, + = resistant | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID574171 | Antibacterial activity against Escherichia coli OCL62 grown as planktonic cells after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID1168632 | Antimicrobial activity against Bacillus cereus NRRL-B-3711 at 10 ug after 18 hrs by agar well diffusion assay | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Phosphorus-nitrogen compounds. Part 29. Syntheses, crystal structures, spectroscopic and stereogenic properties, electrochemical investigations, antituberculosis, antimicrobial and cytotoxic activities and DNA interactions of ansa-spiro-ansa cyclotetrapho |
| AID565675 | Antimicrobial activity against beta-lactamase negative ampicillin-susceptible Haemophilus influenzae harboring fst1 mutant gene by broth microdilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID625286 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatitis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID1434052 | Antibacterial activity against Staphylococcus aureus NCIM 2901 by standard agar method | 2017 | Bioorganic & medicinal chemistry letters, 02-01, Volume: 27, Issue:3 | Antileishmanial evaluation of clubbed bis(indolyl)-pyridine derivatives: One-pot synthesis, in vitro biological evaluations and in silico ADME prediction. |
| AID1870139 | Antibacterial activity against wild type methicillin resistant Staphylococcus aureus 5017/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID595276 | Antimicrobial activity against Staphylococcus aureus at 1 mg/ml after 24 hrs by agar well diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Applications of 2-arylhydrazononitriles in synthesis: preparation of new indole containing 1,2,3-triazole, pyrazole and pyrazolo[1,5-a]pyrimidine derivatives and evaluation of their antimicrobial activities. |
| AID1382082 | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 18 to 24 hrs by double microdilution method | 2018 | European journal of medicinal chemistry, Feb-25, Volume: 146 | Ciprofloxacin derivatives and their antibacterial activities. |
| AID324231 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoU mutant assessed as cell count in stationary phase at 100 ug/ml after 5 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID562223 | Antimicrobial activity against Desulfovibrio desulfuricans MB by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID460801 | Antibacterial activity against Acinetobacter baumannii 3304 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID572266 | Antibacterial activity against Prevotella oralis by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID584848 | Ratio of Kcat to Km for Aeromonas allosaccharophila AL-1 beta-lactamase PER2 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | PER-6, an extended-spectrum beta-lactamase from Aeromonas allosaccharophila. |
| AID561729 | Antibacterial activity against Enterococcus faecalis assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID1159098 | Antimicrobial activity against Klebsiella pneumoniae ATCC 13882 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID405317 | Antibacterial activity against Haemophilus influenzae group IId isolates with ftsI gene mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID535749 | Antimicrobial activity against community-acquired Escherichia coli expressing extended spectrum beta-lactamase obtained from patient with intra-abdominal infection assessed as susceptible isolates by EUCAST method in presence of beta-lactamase inhibitor S | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Incidence and antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae with extended-spectrum beta-lactamases in community- and hospital-associated intra-abdominal infections in Europe: results of the 2008 Study for Monitoring Antimicrob |
| AID544584 | Antimicrobial activity against Escherichia coli ATCC 25922 by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Pyrosequencing using the single-nucleotide polymorphism protocol for rapid determination of TEM- and SHV-type extended-spectrum beta-lactamases in clinical isolates and identification of the novel beta-lactamase genes blaSHV-48, blaSHV-105, and blaTEM-155 |
| AID662987 | Antibacterial activity against Streptococcus pneumoniae MTCC 1936 by macrobroth dilution assay | 2012 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 22, Issue:12 | An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidines. |
| AID278267 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS18 tolC::Kan with GyrA S38F mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1399493 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hrs by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID1907031 | Antibacterial activity against Escherichia coli acraB strain assessed as inhibition of bacterial growth incubated for 8 hrs by CLSI protocol based microdilution assay | 2022 | Journal of medicinal chemistry, 04-14, Volume: 65, Issue:7 | Design, Synthesis, and Proof-of-Concept of Triple-Site Inhibitors against Aminoacyl-tRNA Synthetases. |
| AID295101 | Antibacterial activity against Klebsiella pneumoniae UC57 at 10 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID544274 | Antimicrobial activity against Enterococcus faecalis NKH4 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID396033 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pBGS18 plasmid by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID757699 | Antibacterial activity against Bacillus subtilis ATCC 6051 assessed as growth inhibition after 24 to 48 hrs by kirby-bauer disc diffusion method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis, antitumor and antibacterial activities of some novel tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives. |
| AID533416 | Antimicrobial activity against Peptoniphilus asaccharolyticus assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID519643 | Antimicrobial activity against Escherichia coli EPI300 transformant harboring pCC1 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID382712 | Antimicrobial activity against Streptococcus pyogenes at 572.4 uM by disc-diffusion method | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives. |
| AID535213 | Antimicrobial activity against Clostridium sporogenes by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1908126 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID1323306 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by serial two fold dilution method | 2016 | Journal of natural products, 07-22, Volume: 79, Issue:7 | Actinomadurol, an Antibacterial Norditerpenoid from a Rare Actinomycete, Actinomadura sp. KC 191. |
| AID1762803 | Antibacterial activity against Escherichia coli 01 assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | 2021 | Bioorganic & medicinal chemistry, 05-15, Volume: 38 | Dipyridyl-substituted thiosemicarbazone as a potent broad-spectrum inhibitor of metallo-β-lactamases. |
| AID521432 | Antibacterial activity against Stenotrophomonas maltophilia isolate KJ deficient in L1 beta lactamase gene at 50 ug/ml | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Induction of L1 and L2 beta-lactamases of Stenotrophomonas maltophilia. |
| AID535473 | Antimicrobial activity against Peptoniphilus harei by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1256873 | Antibacterial activity against Escherichia coli after 48 hrs | 2015 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 25, Issue:22 | Synthesis and evaluation of antibacterial activity of (R)-2-methylheptyl isonicotinate, a putative naturally occurring bioactive agent. |
| AID529619 | Antibacterial activity against Beta-lactamase positive Haemophilus influenzae assessed as susceptible isolates after 20 to 24 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID665058 | Antibacterial activity against Bacillus subtilis MTCC 441 after 24 hrs by micro-broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 22, Issue:11 | An efficient one-pot synthesis, structure, antimicrobial and antioxidant investigations of some novel quinolyldibenzo[b,e][1,4]diazepinones. |
| AID442403 | Antimicrobial activity against Escherichia coli at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID565674 | Antimicrobial activity against beta-lactamase negative ampicillin-susceptible Haemophilus influenzae harboring fst1 mutant gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID1075999 | Antibacterial activity against Bacillus subtilis NCIM 2063 by standard agar method | 2014 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 24, Issue:6 | Synthesis, antileishmanial activity and docking study of N'-substitutedbenzylidene-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetohydrazides. |
| AID535455 | Antimicrobial activity against Lactobacillus rhamnosus by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID535635 | Antimicrobial activity against Group B streptococcus serotype VI R5 harboring F395L, V405A, R433H, H438Y, and G648A mutations in PBP 2X and T567I mutation in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID369439 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecalis after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID529583 | Antibacterial activity against Escherichia coli TP1 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID536091 | Antimicrobial activity against Pseudomonas aeruginosa IFO 3448 after 24 hrs | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID1331876 | Antibacterial activity against Klebsiella pneumoniae ATCC 27736 | 2017 | Bioorganic & medicinal chemistry, 01-01, Volume: 25, Issue:1 | Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. |
| AID565752 | Antimicrobial activity against Enterococcus faecalis clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID529627 | Antibacterial activity against Beta-lactamase positive Haemophilus influenzae isolate harboring fst1 mutant gene after 20 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID572253 | Antibacterial activity against Bacteroides splanchnicus by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1304322 | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 SF8300 assessed as zone of inhibition at 10 ug after 18 hrs by disk diffusion method | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | Caged xanthones: Potent inhibitors of global predominant MRSA USA300. |
| AID477031 | Antifungal activity against Botrytis fabae at 2 mg/ml after 7 days by agar diffusion assay | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activities of some new thiazole and pyrazole derivatives based on 4,5,6,7-tetrahydrobenzothiophene moiety. |
| AID520991 | Antimicrobial activity against Brucella abortus 2308 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Novel antimicrobial peptides that exhibit activity against select agents and other drug resistant bacteria. |
| AID555219 | Antibacterial activity against Escherichia coli DH5alpha carrying ampC gene of Acinetobacter genomosp. 3 isolate 69 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID573357 | Antibacterial activity against ceftazidime-nonsusceptible Escherichia coli assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID535189 | Antimicrobial activity against Clostridium hastiforme by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID546619 | Antimicrobial activity against Escherichia coli harboring beta-lactamase VIM-18 by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). |
| AID389005 | Antibacterial activity against Escherichia coli ATCC 11229 assessed as diameter of the inhibition zone at 1 uM/disk after 4 hrs by disk diffusion method | 2008 | Bioorganic & medicinal chemistry, Dec-01, Volume: 16, Issue:23 | Hetero-Diels-Alder reaction of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with arylsulfonylcyanides. Synthesis and antimicrobial activity of 4-hydroxy-2-(arylsulfonyl)pyridines. |
| AID763998 | Antibacterial activity against Staphylococcus aureus ATCC 6538P assessed as diameter of inhibition zone at 1 mg/ml after 24 hrs by cup diffusion method (Rvb = 15 mm) | 2013 | European journal of medicinal chemistry, Aug, Volume: 66 | Synthesis, biological evaluation and molecular docking studies of some pyrimidine derivatives. |
| AID1594838 | Bactericidal activity against Micrococcus flavus ATCC 10240 by microdilution method | 2019 | Journal of natural products, 06-28, Volume: 82, Issue:6 | Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. |
| AID324242 | Antibacterial activity against Escherichia coli K12 containing deletion deltaPhoU mutant assessed as cell count in log phase at 100 ug/ml after 10 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID444056 | Fraction escaping gut-wall elimination in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID665059 | Antibacterial activity against Salmonella typhi MTCC 98 after 24 hrs by micro-broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 22, Issue:11 | An efficient one-pot synthesis, structure, antimicrobial and antioxidant investigations of some novel quinolyldibenzo[b,e][1,4]diazepinones. |
| AID278559 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium bifidum R0071 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID557438 | Antimicrobial activity in Prevotella bivia by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID283560 | Antibacterial activity against Escherichia coli HNCE4 after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. |
| AID585395 | Activity at Bradyrhizobium japonicum metallo-beta-lactamase BJP-1 | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides. |
| AID543807 | Bactericidal activity against Haemophilus influenzae VT450-2006 assessed as eradication of pre-formed biofilm at 50 times MIC after 24 hrs by serial dilution | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID1627297 | Antibacterial activity against Escherichia coli ATCC 25922 by broth microdilution method | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16 | New antibacterial agents: Hybrid bioisoster derivatives as potential E. coli FabH inhibitors. |
| AID543805 | Bactericidal activity against Streptococcus pyogenes VT 59 assessed as eradication of pre-formed biofilm at 1 to 10 times MIC after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID535239 | Antimicrobial activity against Bifidobacterium longum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID622561 | Antimicrobial activity against Vibrio cholerae MTCC 3906 for 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 21, Issue:20 | Microwave assisted synthesis and antimicrobial evaluation of new fused pyran derivatives bearing 2-morpholinoquinoline nucleus. |
| AID1372806 | Antimicrobial activity against Escherichia coli NCTC 10418 by two-fold serial dilution assay | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2 | An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold. |
| AID565448 | Antimicrobial activity against Streptococcus intermedius SI006 biofilm harboring luxS mutant gene assessed as biofilm bacterial count at 0.06 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =413.7 +/- 24.47 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID625282 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID255537 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 4.0 uM/ml in dimethylformamide, + = resistant | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID1436577 | Antibacterial activity against Vibrio cholerae MTCC 3906 by broth microdilution assay method | 2017 | Bioorganic & medicinal chemistry letters, 02-01, Volume: 27, Issue:3 | Synthesis, identification and in vitro biological evaluation of some novel quinoline incorporated 1,3-thiazinan-4-one derivatives. |
| AID1721977 | Bactericidal activity against Pseudomonas fluorescens | 2020 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 30, Issue:17 | New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. |
| AID318711 | Antimicrobial activity against Staphylococcus haemolyticus by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID717351 | Antimicrobial activity against Staphylococcus aureus ATCC 6538p after 24 hrs | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12 | Brominated aromatic furanones and related esters from the ascidian Synoicum sp. |
| AID405818 | Antimicrobial activity against Acinetobacter sp. 5248 isolate harboring bla IMP-1 carrying integron In86 containing aminoglycoside resistance gene aac(6')-3 | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital. |
| AID572037 | Antibacterial activity against Clostridium disporicum by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1114118 | Antibacterial activity against Staphylococcus aureus 14001 assessed as growth inhibition by broth microdilution method | 2013 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, May, Volume: 22, Issue:5 | Microbiologically active Mannich bases derived from 1,2,4-triazoles. The effect of C-5 substituent on antibacterial activity. |
| AID535477 | Antimicrobial activity against Peptostreptococcus micros by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID600681 | Bactericidal activity against Micrococcus flavus ATCC 10240 after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID565743 | Antimicrobial activity against Enterococcus faecium expressing VanB gene clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID587194 | Antimicrobial activity against Pseudomonas aeruginosa after 18 hrs by broth microdilution method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Comazaphilones A-F, azaphilone derivatives from the marine sediment-derived fungus Penicillium commune QSD-17. |
| AID1378891 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as diameter of inhibition zone at 100 uM after 24 hrs by cup diffusion method | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Synthesis, antimicrobial, DNA cleavage and antioxidant activities of tricyclic sultams derived from saccharin. |
| AID757698 | Antibacterial activity against Staphylococcus aureus ATCC 12600 assessed as growth inhibition after 24 to 48 hrs by kirby-bauer disc diffusion method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis, antitumor and antibacterial activities of some novel tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives. |
| AID1471211 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by spectrophotometric method | 2017 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 27, Issue:13 | Diversity-oriented sustainable synthesis of antimicrobial spiropyrrolidine/thiapyrrolizidine oxindole derivatives: New ligands for a metallo-β-lactamase from Klebsiella pneumonia. |
| AID572032 | Antibacterial activity against Clostridium bartlettii by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID396029 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate in presence of 20 ug/ml efflux pump inhibitor Phe-Arg-beta-naphthylamide by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID535471 | Antimicrobial activity against Peptoniphilus asaccharolyticus by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID287240 | Antimicrobial activity against Bacillus subtilis IFO 3007 after 24 hrs | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles. |
| AID429267 | Antibacterial activity against Escherichia coli at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents. |
| AID562931 | Antimicrobial activity against Clostridium difficile 6269 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID442428 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID558537 | Antibacterial activity against bla gene-positive and nitrocefin reaction-positive beta-lactamase harboring Campylobacter coli isolate P321 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID360060 | Inhibition of Enterococcus faecium M512 LDtfm transpeptidase activity assessed as tri-aspartate-tetra multimer containing L-Lys3 to D-Asp-L-Lys3 cross links at 8 ug/ml | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID386969 | Antimicrobial activity Klebsiella pneumoniae at 25 ug/mL after 24 hrs by agar diffusion technique | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10 | Synthesis and antimicrobial activity of some new heterocycles incorporating antipyrine moiety. |
| AID535247 | Antimicrobial activity against Colinsella aerofaciens by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1594841 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 by microdilution method | 2019 | Journal of natural products, 06-28, Volume: 82, Issue:6 | Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. |
| AID255539 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 0.5 uM/ml in dimethylformamide, + = resistant | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID662083 | Antibacterial activity against Vibrio alginolyticus after 20 hrs by liquid growth inhibition assay | 2012 | Journal of medicinal chemistry, Mar-08, Volume: 55, Issue:5 | From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity. |
| AID278270 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS38 acrAB::Kan with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID405314 | Antibacterial activity against Haemophilus influenzae group IIa isolates with ftsI gene mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID561445 | Antibacterial activity against Escherichia coli DH10B harboring plasmid BCSK carrying beta-lactamase CMY-44 gene by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Reduced susceptibility to cefepime among Escherichia coli clinical isolates producing novel variants of CMY-2 beta-lactamase. |
| AID1821094 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as inhibition of bacterial growth incubated for 24 hr by CLSI based broth microdilution method | |||
| AID1577960 | Antimicrobial activity against Klebsiella pneumoniae ATCC 8303 under iron-deficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID400384 | Antibacterial activity against Salmonella typhi at 200 ug/100uL after 24 hrs by agar well diffusion method | 1998 | Journal of natural products, Feb, Volume: 61, Issue:2 | Antibacterial steroidal alkaloids from Sarcococca saligna. |
| AID314288 | Effect on disruption of membrane integrity using 1-palmitolyl-2-oleoyl-sn-glycero-3-[phospho-rac-(1-glycerol)] lipid vesicle at 70 uM by calcein dye leakage assay | 2008 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 18, Issue:4 | Synthesis and biological evaluation of novel 1,3,5-triazine derivatives as antimicrobial agents. |
| AID534731 | Antimicrobial activity against Bacteroides stercoris by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID536089 | Antimicrobial activity against Micrococcus luteus IFO 3232 after 24 hrs | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID585872 | Antimicrobial activity against Pseudomonas aeruginosa isolate 16 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1733175 | Antibacterial activity against Staphylococcus aureus assessed as bacterial growth inhibition measured after 24 hrs by broth dilution assay | 2021 | Bioorganic & medicinal chemistry letters, 05-01, Volume: 39 | Synthesis and antibacterial activities of marine natural product ianthelliformisamines and subereamine synthetic analogues. |
| AID1668060 | Inhibition of DHPS in Staphylococcus epidermidis assessed as antibacterial activity by measuring inhibition of bacterial growth incubated for 24 hrs by microbroth dilution method | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9 | New acrylamide-sulfisoxazole conjugates as dihydropteroate synthase inhibitors. |
| AID318659 | Antibacterial activity against Atopobium parvulum GAI 5542 by broth microdilution method | 2008 | Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7 | Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens. |
| AID467966 | Antimicrobial activity against Enterococcus faecalis ATCC 19433 after 18 to 24 hrs by liquid broth method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. |
| AID564809 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID584846 | Activity at Aeromonas allosaccharophila AL-1 beta-lactamase PER6 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | PER-6, an extended-spectrum beta-lactamase from Aeromonas allosaccharophila. |
| AID1591740 | Antibacterial activity against Bacillus subtilis MTCC 441 after 24 hrs by serial dilution method | 2019 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 29, Issue:16 | Rational design, molecular docking and synthesis of novel homopiperazine linked imidazo[1,2-a]pyrimidine derivatives as potent cytotoxic and antimicrobial agents. |
| AID595441 | Antibacterial activity against Staphylococcus aureus ATCC 6538p after 24 hrs by by twofold serial dilution method | 2011 | Journal of natural products, Apr-25, Volume: 74, Issue:4 | Scalarane sesterterpenes from the sponge Hyatella sp. |
| AID1762802 | Antibacterial activity against methicillin-resistant Staphylococcus aureus assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | 2021 | Bioorganic & medicinal chemistry, 05-15, Volume: 38 | Dipyridyl-substituted thiosemicarbazone as a potent broad-spectrum inhibitor of metallo-β-lactamases. |
| AID278527 | Antimicrobial activity against Bifidobacterium longum ATCC 15707 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1379745 | Antimicrobial activity against Bacillus cereus incubated for 24 hrs by disc diffusion assay | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of cyclopenta(hepta)[b]thiophene and fused cyclohepta[b]thiophene analogs. |
| AID1535456 | Effect on cell viability of Pseudoalteromonas ulvae TC14 at 5 uM measured after 6 hrs by resazurin dye based fluorescence assay | 2019 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 29, Issue:4 | Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds? |
| AID1648088 | Antibacterial activity against Salmonella enterica ATCC 14028 assessed as reduction in microbial growth after 24 hrs by two-fold serial dilution method | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Absolute Configuration and Antibiotic Activity of Piceamycin. |
| AID372566 | Antibacterial activity against beta-lactamase-negative ampicillin-resistant Haemophilus influenzae with mutation in AcrAB repressor gene arcR | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID547762 | Antimicrobial activity against Klebsiella pneumoniae 1534 expressing beta-lactamase KPc-2 by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID585398 | Ratio of Kcat to Km for Stenotrophomonas maltophilia 1SML metallo-beta-lactamase L1 | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides. |
| AID555250 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 65 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1870153 | Antibacterial activity against wild type Staphylococcus aureus 4461/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID360067 | Inhibition of Enterococcus faecium M512 LDtfm transpeptidase activity assessed as tri-aspartate-tri-aspartate-penta-aspartate multimer containing L-Lys3 to D-Asp-L-Lys3 cross links at 8 ug/ml | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID405328 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae group IIc isolates with acrR mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID520710 | Antibacterial activity against Acinetobacter baumannii MAD by disk diffusion method in presence of 4 ug/ml clavulanic acid | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID396030 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pAP2 plasmid containing Enterobacter cloacae acrA gene by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID584480 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN10 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID572045 | Antibacterial activity against Clostridium spiroforme by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID564810 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID745302 | Antifungal activity against Aspergillus fumigatus MTCC 3008 assessed as growth inhibition after overnight incubation by NCCLS broth microdilution method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Synthesis and identification of β-aryloxyquinoline based diversely fluorine substituted N-aryl quinolone derivatives as a new class of antimicrobial, antituberculosis and antioxidant agents. |
| AID585876 | Antimicrobial activity against Pseudomonas aeruginosa isolate 18 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID519656 | Antimicrobial activity against Escherichia coli Irk1224 type 1 mutant harboring beta-lactamase CTX-M-3 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID1399494 | Bactericidal activity against Listeria monocytogenes NCTC 7973 by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID548741 | Antimicrobial activity against Vancomycin-susceptible Enterococcus faecalis assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID1264893 | Antimicrobial activity against Bacillus subtilis ATCC 6051 for 17 to 48 hrs by MTT assay | 2015 | Journal of natural products, Nov-25, Volume: 78, Issue:11 | Identification of Elaiophylin Skeletal Variants from the Indonesian Streptomyces sp. ICBB 9297. |
| AID549336 | Antimicrobial activity against Escherichia coli isolate 49 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID1471047 | Antibacterial activity against Staphylococcus aureus NCIM 2602 measured after 12 hrs | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID776458 | Antimicrobial activity against Bacillus cereus 702 Roma at 10 ug | 2013 | European journal of medicinal chemistry, Nov, Volume: 69 | Design, synthesis and biological activities of some 7-aminocephalosporanic acid derivatives. |
| AID1141102 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 after 24 to 48 hrs by two-fold broth microdilution method | 2014 | Bioorganic & medicinal chemistry, May-15, Volume: 22, Issue:10 | Exploring 5-nitrofuran derivatives against nosocomial pathogens: synthesis, antimicrobial activity and chemometric analysis. |
| AID474367 | Antibacterial activity against Staphylococcus aureus | 2010 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 20, Issue:8 | Antimicrobial selaginellin derivatives from Selaginella pulvinata. |
| AID564828 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus simulans after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1225332 | Antimicrobial activity against Proteus hauseri incubated for 24 hrs | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Alkaloidal metabolites from a marine-derived Aspergillus sp. fungus. |
| AID535743 | Antimicrobial activity against community-acquired Klebsiella pneumoniae obtained from patient with intra-abdominal infection assessed as susceptible isolates by EUCAST method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Incidence and antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae with extended-spectrum beta-lactamases in community- and hospital-associated intra-abdominal infections in Europe: results of the 2008 Study for Monitoring Antimicrob |
| AID543799 | Bactericidal activity against Acinetobacter baumannii VT 126 assessed as eradication of pre-formed biofilm at 1 to 10 times MIC after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID1769964 | Antibacterial activity against Enterococcus faecalis ATCC29212 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID535491 | Antimicrobial activity against Ruminococcus torques by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID535453 | Antimicrobial activity against Lactobacillus reuteri by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID533426 | Antimicrobial activity against Peptostreptococcus sp. by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID389387 | Antibacterial activity against Proteus vulgaris ATCC 3851 | 2008 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 18, Issue:20 | Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp. |
| AID494532 | Antimicrobial activity against Bacillus subtilis NCIM 2718 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID494532 | Antimicrobial activity against Bacillus subtilis NCIM 2718 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May-06 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID278246 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-4 acrAB::Kan with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID436467 | Antibacterial activity against Escherichia coli ATCC 25922 after 20 hrs by two fold dilution method | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10 | Synthesis, physicochemical properties and antimicrobial activity of some new benzimidazole derivatives. |
| AID1721972 | Antibacterial activity against Pseudomonas fluorescens by microdilution method | 2020 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 30, Issue:17 | New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. |
| AID551094 | Antibacterial activity against Streptococcus pyogenes by liquid dilution method | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1 | 3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents. |
| AID757694 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis, antitumor and antibacterial activities of some novel tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives. |
| AID287243 | Antimicrobial activity against Candida albicans IFO 0583 after 48 hrs | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles. |
| AID535445 | Antimicrobial activity against Lactobacillus catenaformis by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1286497 | Bactericidal activity against methicillin-sensitive Staphylococcus aureus ATCC 25923 after 24 and 48 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID1596673 | Bactericidal activity against Staphylococcus aureus ATCC 6538 incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID374023 | Activity of Enterobacter cloacae IMI1 beta lactamase expressed in Escherichia coli DH5alpha by SDS-PAGE | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase. |
| AID529900 | Antimicrobial activity against Leptospira interrogans serovar Icterohaemorrhagiae isolate 9 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID533398 | Antimicrobial activity against Clostridium paraputrificum by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID547191 | Antibacterial activity against Campylobacter jejuni by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID295110 | Antibacterial activity against Bacillus cereus ATCC 7064 at 10 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID510748 | Antibacterial activity against Escherichia coli AG102MB harboring naive acrB gene | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. |
| AID678540 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 | 2012 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 22, Issue:18 | Design, solvent free synthesis, and antimicrobial evaluation of 1,4 dihydropyridines. |
| AID64890 | Influence of porins and TonB on antibacterial activity in Escherichia coli (PLB268) using agar diffusion assay | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID547766 | Antimicrobial activity against Escherichia coli DH10B harboring plasmid pBR322-catI carrying beta-lactamase KPC-2 by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID1591743 | Antibacterial activity against Pseudomonas sp. 2496 after 24 hrs by serial dilution method | 2019 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 29, Issue:16 | Rational design, molecular docking and synthesis of novel homopiperazine linked imidazo[1,2-a]pyrimidine derivatives as potent cytotoxic and antimicrobial agents. |
| AID533386 | Antimicrobial activity against Clostridium difficile by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID463412 | Antimicrobial activity against Bacillus subtilis after 24 hrs by liquid dilution method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines. |
| AID1721978 | Bactericidal activity against Erwinia amylovora | 2020 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 30, Issue:17 | New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. |
| AID278229 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21 gyrA+ | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID372561 | Antibacterial activity against genetically beta-lactamase-negative ampicillin-resistant Haemophilus influenzae type b with an amino acid substitution in highly mutated locus Ser-385 of ftsI gene assessed as resistance rate by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID1272238 | Antibacterial activity against Streptococcus pyogenes by broth micro-dilution method | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3 | Efficiently functionalized oxacalix[4]arenes: Synthesis, characterization and exploration of their biological profile as novel HDAC inhibitors. |
| AID1424101 | Antibacterial activity against Bacillus subtilis CMCC63501 | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | Antibacterial Compounds from Marine Bacteria, 2010-2015. |
| AID1471209 | Antibacterial activity against Escherichia coli ATCC 9637 by spectrophotometric method | 2017 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 27, Issue:13 | Diversity-oriented sustainable synthesis of antimicrobial spiropyrrolidine/thiapyrrolizidine oxindole derivatives: New ligands for a metallo-β-lactamase from Klebsiella pneumonia. |
| AID1193890 | Antimicrobial activity against Bacillus subtilis MTCC 441 assessed as zone of inhibition at 5 mg/ml after 24 hrs by agar well diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Rapid 'one-pot' synthesis of a novel benzimidazole-5-carboxylate and its hydrazone derivatives as potential anti-inflammatory and antimicrobial agents. |
| AID1436574 | Antibacterial activity against Clostridium tetani MTCC 449 by broth microdilution assay method | 2017 | Bioorganic & medicinal chemistry letters, 02-01, Volume: 27, Issue:3 | Synthesis, identification and in vitro biological evaluation of some novel quinoline incorporated 1,3-thiazinan-4-one derivatives. |
| AID510559 | Antibacterial activity against Escherichia coli AG102MB | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. |
| AID539559 | Antimicrobial activity against Proteus vulgaris ATCC 3851 | 2010 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 20, Issue:23 | Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase. |
| AID441925 | Antibacterial activity against Micrococcus luteus WT after 24 hrs by NCCLS method | 2009 | Journal of medicinal chemistry, Nov-12, Volume: 52, Issue:21 | Coordination chemistry based approach to lipophilic inhibitors of 1-deoxy-D-xylulose-5-phosphate reductoisomerase. |
| AID600686 | Bactericidal activity against Enterococcus faecalis isolate obtained from human after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID546209 | Antimicrobial activity against Staphylococcus aureus 2171 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Identification of the novel dfrK-carrying transposon Tn559 in a porcine methicillin-susceptible Staphylococcus aureus ST398 strain. |
| AID1228013 | Antimicrobial activity against Proteus vulgaris CMCC 49027 assessed as complete prevention of visible growth after incubation at 37 degC for 18 to 20 hrs | 2015 | Journal of natural products, Apr-24, Volume: 78, Issue:4 | Antibacterial Biphenanthrenes from the Fibrous Roots of Bletilla striata. |
| AID564812 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus haemolyticus after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID572257 | Antibacterial activity against Prevotella bivia by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID395814 | Antibacterial activity against Streptomyces chartreusis NRRL 11407 at 300 ug/disk after 24 hrs by paper disk diffusion test | 2008 | European journal of medicinal chemistry, Nov, Volume: 43, Issue:11 | Synthesis and biological evaluation of diversely substituted indolin-2-ones. |
| AID546955 | Antibacterial activity against Shigella boydii assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1204382 | Antimicrobial activity against Staphylococcus aureus assessed as diameter of inhibition zone after 2 days by agar diffusion assay | 2015 | European journal of medicinal chemistry, Jun-05, Volume: 97 | Organoselenocyanates and symmetrical diselenides redox modulators: Design, synthesis and biological evaluation. |
| AID409950 | Inhibition of human brain MAOA | 2008 | Journal of medicinal chemistry, Nov-13, Volume: 51, Issue:21 | Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. |
| AID528718 | Antibacterial activity against vancomycin resistant Enterococcus faecium VanB clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID405308 | Antibacterial activity against beta-lactamase positive ampicillin resistant Haemophilus influenzae isolate assessed as percent resistant isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID585851 | Antimicrobial activity against Pseudomonas aeruginosa isolate 6 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1439796 | Antibacterial activity against Staphylococcus aureus MTCC 96 at 100 ug incubated for 24 hrs under dark condition by agar well diffusion method | 2017 | Bioorganic & medicinal chemistry letters, 04-01, Volume: 27, Issue:7 | Biologically active perspective synthesis of heteroannulated 8-nitroquinolines with green chemistry approach. |
| AID1329751 | Antibacterial activity against Salmonella typhimurium ATCC 13311 after 24 hrs by broth microdilution method | |||
| AID279559 | Antimicrobial activity against Haemophilus influenzae strains causing clinical infections | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Diversity of ampicillin resistance genes and antimicrobial susceptibility patterns in Haemophilus influenzae strains isolated in Korea. |
| AID557982 | Antimicrobial activity in Clostridium cadaveris by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID565746 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecium clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID421840 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 | 2009 | Journal of natural products, Feb-27, Volume: 72, Issue:2 | Glionitrin A, an antibiotic-antitumor metabolite derived from competitive interaction between abandoned mine microbes. |
| AID405319 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae group IIa isolates with acrR aminoacid substitution mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID1854169 | Antimicrobial activity against Pseudomonas aeruginosa MCCB 0035 | 2022 | European journal of medicinal chemistry, Aug-05, Volume: 238 | Cascade synthetic strategies opening access to medicinal-relevant aliphatic 3- and 4-membered N-heterocyclic scaffolds. |
| AID382696 | Antimicrobial activity against Klebsiella pneumoniae at 572.4 uM by disc-diffusion method | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives. |
| AID471914 | Antibacterial activity against Pseudomonas putida MTCC 1072 at 64 ug/ml after 16 hrs by disc diffusion method | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | A facile one-pot green synthesis and antibacterial activity of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes. |
| AID334000 | Antibacterial activity against Escherichia coli assessed per 100 uL of nutrient broth after 24 hrs by tube broth dilution method | 1997 | Journal of natural products, Oct, Volume: 60, Issue:10 | New steroidal alkaloids from Buxus longifolia. |
| AID540865 | Antimicrobial activity against Salmonella enterica serovar enteritidis isolate 104-cip harboring gyrA D87Y,S83F mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID324175 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid vector at 6 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID572029 | Antibacterial activity against Clostridium perfringens by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID436784 | Antifungal activity against Penicillium chrysogenum Thom AUCC 530 at 25 ug/mL after 24 hrs by agar diffusion assay | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10 | Synthesis, characterization and in vitro antimicrobial activity of novel 2-thioxo-4-thiazolidinones and 4,4'-bis(2-thioxo-4-thiazolidinone-3-yl)diphenylsulfones. |
| AID530520 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype V isolate 9171-03 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID1593645 | Bactericidal activity against Bacillus subtilis NBRC 3134 incubated for 18 hrs followed by inoculums transfer to MHA plate and further incubated for 24 hrs | 2019 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 29, Issue:11 | Synthesis, antibacterial and cytotoxic evaluation of flavipucine and its derivatives. |
| AID1697866 | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as zone of inhibition at 4 mg/ml incubated for 24 hrs by agar well diffusion method | |||
| AID360072 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as tetra -aspartate-tetra-aspartate multimer containing D-Ala4 to D-Asp-L-Lys3 cross links at 128 ug/ml by mass spectrometry | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID564823 | Antimicrobial activity against methicillin-susceptible Staphylococcus aureus assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID283321 | Antimicrobial activity against Escherichia coli XL10/vector | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Detection of a new SHV-type extended-spectrum beta-lactamase, SHV-31, in a Klebsiella pneumoniae strain causing a large nosocomial outbreak in The Netherlands. |
| AID528526 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B7 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID613613 | Antibacterial activity against 10'8 CFU/mL Salmonella typhi MTCC 98 by NCCLS M100-S12(M7) broth microdilution method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis and identification of β-aryloxyquinolines and their pyrano[3,2-c]chromene derivatives as a new class of antimicrobial and antituberculosis agents. |
| AID285199 | Antimicrobial activity against Escherichia coli M093 mutant with AG100 lon3::IS186 acrR::IS1 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID540826 | Antimicrobial activity against ramA::aph-deficient ciprofloxacin-resistant Salmonella enterica serovar enteritidis isolate 5408-cip harboring gyrA D87Y, gyrB E466D, parE V461G mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID1194189 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs by two fold serial microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 25, Issue:8 | Studies on antimicrobial effects of four ligands and their transition metal complexes with 8-mercaptoquinoline and pyridine terminal groups. |
| AID405325 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae group IIc isolates with acrR base A insertion behind nucleotide 361 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID1754160 | Antibacterial activity against Staphylococcus aureus measured by broth microdilution method | 2021 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 43 | Synthesis and biological evaluation of novel benzo[a]pyridazino[3,4-c]phenazine derivatives. |
| AID324989 | Antibacterial activity against rifampin-resistant Haemophilus influenzae RdRIF by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID442406 | Antimicrobial activity against Salmonella Typhimurium at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID557430 | Antimicrobial activity in Bacteroides uniformis by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID573355 | Antibacterial activity against ceftazidime-nonsusceptible Escherichia coli by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1320836 | Activity of native signal containing Klebsiella pneumoniae OXA-48 assessed as ratio of Kcat to Km by Michaelis-Menten kinetics assay | 2016 | Journal of medicinal chemistry, 06-09, Volume: 59, Issue:11 | Screening and Design of Inhibitor Scaffolds for the Antibiotic Resistance Oxacillinase-48 (OXA-48) through Surface Plasmon Resonance Screening. |
| AID504050 | Antimicrobial activity against Bacillus subtilis MTCC 441 by broth microdilution technique | 2010 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 20, Issue:18 | Synthesis and antimicrobial activity of novel fluorine containing 4-(substituted-2-hydroxybenzoyl)-1H-pyrazoles and pyrazolyl benzo[d]oxazoles. |
| AID1228008 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as complete prevention of visible growth after incubation at 37 degC for 18 to 20 hrs | 2015 | Journal of natural products, Apr-24, Volume: 78, Issue:4 | Antibacterial Biphenanthrenes from the Fibrous Roots of Bletilla striata. |
| AID564817 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus hominis after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1185700 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 10145 after 24 hrs by agar dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | New thiophene-1,2,4-triazole-5(3)-ones: highly bioactive thiosemicarbazides, structures of Schiff bases and triazole-thiols. |
| AID1668059 | Inhibition of DHPS in Bacillus subtilis assessed as antibacterial activity by measuring inhibition of bacterial growth incubated for 24 hrs by microbroth dilution method | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9 | New acrylamide-sulfisoxazole conjugates as dihydropteroate synthase inhibitors. |
| AID1079947 | Comments (NB not yet translated). [column 'COMMENTAIRES' in source] | |||
| AID1157881 | Antimicrobial activity against Bacillus subtilis ATCC 6633 after 24 hrs by two-fold broth dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Suvanine sesterterpenes and deacyl irciniasulfonic acids from a tropical Coscinoderma sp. sponge. |
| AID1439799 | Antibacterial activity against Bacillus subtilis MTCC 121 incubated for 24 hrs under dark condition by microwell dilution method | 2017 | Bioorganic & medicinal chemistry letters, 04-01, Volume: 27, Issue:7 | Biologically active perspective synthesis of heteroannulated 8-nitroquinolines with green chemistry approach. |
| AID666962 | Antibacterial activity against Salmonella typhi MTCC 98 by broth microdilution method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | New N-arylamino biquinoline derivatives: synthesis, antimicrobial, antituberculosis, and antimalarial evaluation. |
| AID1201597 | Antibacterial activity against Streptomyces scabiei CGMCC4.7610246 assessed as growth inhibition after 36 hrs by turbidimetric analysis | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Pentacyclic triterpene derivatives possessing polyhydroxyl ring A inhibit gram-positive bacteria growth by regulating metabolism and virulence genes expression. |
| AID1411631 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 incubated for 24 hrs followed by serial sub-cultivation and measured after 24 hrs by microdilution method | |||
| AID583094 | Activity of Escherichia coli XL1-Blue wild-type VIM-2 beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID287696 | Antibacterial activity against Enterococcus faecalis ATCC 29212 by broth microdilution method | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6 | Synthesis and structure-antibacterial activity relationship investigation of isomeric 2,3,5-substituted perhydropyrrolo[3,4-d]isoxazole-4,6-diones. |
| AID1194193 | Antimicrobial activity against Saccharomyces cerevisiae after 48 hrs by two fold serial microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 25, Issue:8 | Studies on antimicrobial effects of four ligands and their transition metal complexes with 8-mercaptoquinoline and pyridine terminal groups. |
| AID623613 | Antibacterial activity against 10'8 CFU/mL Staphylococcus aureus MTCC 96 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID519109 | Antibacterial activity against Proteus mirabilis M 48 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID318709 | Antimicrobial activity against penicillin-resistant Staphylococcus epidermidis ATCC 12228 by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID287377 | Antibacterial activity against Mycobacterium smegmatis after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID520384 | Antimicrobial activity Escherichia coli DH5alpha expressing beta lactamase VIM-2 by agar macrodilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain. |
| AID542737 | Antimicrobial activity against Klebsiella pneumoniae D24 expressing aac(6')-Ib-cr and CTX-M-9G genes by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID535229 | Antimicrobial activity against Bifidobacterium adolescentis by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID405303 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae isolate by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID283320 | Antimicrobial activity against Klebsiella pneumoniae KPN15-NL | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Detection of a new SHV-type extended-spectrum beta-lactamase, SHV-31, in a Klebsiella pneumoniae strain causing a large nosocomial outbreak in The Netherlands. |
| AID322318 | Antibacterial activity against CTX-M group 9 enzyme producing Escherichia coli isolates assessed as percent nonsusceptible isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal. |
| AID530217 | Antimicrobial activity against Mycobacterium bovis BCG ML1048 carrying transposon IS1096::Km inserted at +519bp of bcg1567c gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1114114 | Antibacterial activity against Micrococcus luteus ATCC 10240 assessed as growth inhibition by broth microdilution method | 2013 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, May, Volume: 22, Issue:5 | Microbiologically active Mannich bases derived from 1,2,4-triazoles. The effect of C-5 substituent on antibacterial activity. |
| AID1323303 | Antibacterial activity against Kocuria rhizophila NBRC 12708 after 24 hrs by serial two fold dilution method | 2016 | Journal of natural products, 07-22, Volume: 79, Issue:7 | Actinomadurol, an Antibacterial Norditerpenoid from a Rare Actinomycete, Actinomadura sp. KC 191. |
| AID405091 | Antimicrobial activity against non-integron carrying Enterobacteriaceae assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Enterobacteriaceae bloodstream infections: presence of integrons, risk factors, and outcome. |
| AID1491155 | Antibacterial activity against Enterococcus faecalis ATCC 29212 by CLSI method | 2017 | Journal of natural products, 05-26, Volume: 80, Issue:5 | Antimicrobial Spirotetronate Metabolites from Marine-Derived Micromonospora harpali SCSIO GJ089. |
| AID1634721 | Antibacterial activity against Streptomyces scabiei CGMCC4.7610246 by microdilution assay | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | 18β-Glycyrrhetinic Acid Derivatives Possessing a Trihydroxylated A Ring Are Potent Gram-Positive Antibacterial Agents. |
| AID1105399 | Antibacterial activity against Staphylococcus aureus MTCC 3160 assessed as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID278530 | Antimicrobial activity against Bifidobacterium longum P/N 601377 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1706153 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as reduction in bacterial growth incubated for 18 hrs by CLSI based broth microdilution assay | |||
| AID1486828 | Antimicrobial activity against Staphylococcus aureus MTCC 96 incubated for overnight by broth micro dilution method | 2017 | Bioorganic & medicinal chemistry, 08-01, Volume: 25, Issue:15 | 1,2,4-Triazole and 1,3,4-oxadiazole analogues: Synthesis, MO studies, in silico molecular docking studies, antimalarial as DHFR inhibitor and antimicrobial activities. |
| AID1286515 | Ratio of MBC for methicillin-resistant Staphylococcus aureus clinical isolate to MIC90 for methicillin-resistant Staphylococcus aureus clinical isolate | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID691425 | Antibacterial activity against Staphylococcus aureus | 2012 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 22, Issue:20 | Zizimauritic acids A-C, three novel nortriterpenes from Ziziphus mauritiana. |
| AID322314 | Antibacterial activity against CTX-M group 1 enzyme producing Escherichia coli isolates assessed as percent resistant isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal. |
| AID557446 | Antimicrobial activity in Prevotella melaninogenica by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID495340 | Antimicrobial activity against Beta-lactamase-positive, ampicillin-cluvulanate-resistant Haemophilus influenzae with Asp350Asn, Met377Ile, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID1231414 | Antibacterial activity against Bacillus cereus ATCC 14579 assessed as growth inhibition at 20 ug after 24 hrs by disc agar diffusion method in presence of sulbactam | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and biological evaluation of caracasine acid derivatives. |
| AID585430 | Antimicrobial activity against oqxAB positive Escherichia coli C600 SP8-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID436469 | Antibacterial activity against Salmonella typhi MTCC 733 after 20 hrs by two fold dilution method | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10 | Synthesis, physicochemical properties and antimicrobial activity of some new benzimidazole derivatives. |
| AID535251 | Antimicrobial activity against Eggerthella lenta by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID634986 | Antibacterial activity against drug-sensitive Staphylococcus aureus ATCC 25923 by broth microdilution method | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1 | Studies on the synthesis and antibacterial activity of 3,6-disubstituted 1,2,4-triazolo[3,4-b]1,3,4-thiadiazoles. |
| AID655699 | Antibacterial activity against Staphylococcus aureus ATCC 11632 at 40 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID1157884 | Antimicrobial activity against Proteus hauseri NBRC 3851 after 24 hrs by two-fold broth dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Suvanine sesterterpenes and deacyl irciniasulfonic acids from a tropical Coscinoderma sp. sponge. |
| AID1114818 | Antibacterial activity against Bacillus cereus 702 Roma after 18 to 24 hr by double microdilution method | 2013 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, Aug, Volume: 22, Issue:8 | |
| AID467609 | Antibacterial activity against Escherichia coli at 2 mg/ml by agar diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new thiazole and thiophene derivatives. |
| AID1471033 | Growth inhibition of Escherichia coli NCIM 2576 at 30 ug/ml measured after 8 hrs relative to control | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID530232 | Antimicrobial activity against Mycobacterium bovis BCG ML1051 carrying transposon IS1096::Km inserted at -420bp of bcg2965 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID542719 | Antimicrobial activity against ESBL-producing Klebsiella pneumoniae clinical isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Widespread dissemination of aminoglycoside resistance genes armA and rmtB in Klebsiella pneumoniae isolates in Taiwan producing CTX-M-type extended-spectrum beta-lactamases. |
| AID325444 | Antibacterial activity against Escherichia coli K12 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID324161 | Antibacterial activity against Escherichia coli K12 mutant JHU313 after 16 hrs by serial dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID304967 | Antibacterial activity against Streptococcus faecalis by broth micro-dilution technique | 2007 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1 | New antifungal flavonoid glycoside from Vitex negundo. |
| AID299665 | Antibacterial activity against Bacillus subtilis ATCC 6633 by broth microdilution method | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Synthesis and evaluation of amphiphilic cationic quinine-derived for antibacterial activity against methicillin-resistant Staphylococcus aureus. |
| AID405304 | Antibacterial activity against beta-lactamase producing amoxicillin-clavulanic acid-resistant Haemophilus influenzae isolate by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID530223 | Antimicrobial activity against Mycobacterium bovis BCG ML1052 carrying transposon IS1096::Km inserted at +78bp of bcg2824 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID535219 | Antimicrobial activity against Clostridium tertium by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID318658 | Antibacterial activity against Streptococcus intermedius GAI 7416 by broth microdilution method | 2008 | Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7 | Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens. |
| AID519117 | Antibacterial activity against Proteus mirabilis M 29 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID1596676 | Antibacterial activity against Enterobacter cloacae clinical isolate after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID1204380 | Antimicrobial activity against Escherichia coli assessed as diameter of inhibition zone after 2 days by agar diffusion assay | 2015 | European journal of medicinal chemistry, Jun-05, Volume: 97 | Organoselenocyanates and symmetrical diselenides redox modulators: Design, synthesis and biological evaluation. |
| AID395733 | Antimicrobial activity against imipenem-susceptible invasive nontypeable Haemophilus influenzae isolate 244 by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | First characterization of heterogeneous resistance to imipenem in invasive nontypeable Haemophilus influenzae isolates. |
| AID64732 | Influence of siderophore receptor on antibacterial activity in Escherichia coli (1875) using agar diffusion assay | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID1347489 | Antibacterial activity against Serratia marcescens assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID535483 | Antimicrobial activity against Ruminococcus lactaris by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1060495 | Antibacterial activity against Pseudomonas aeruginosa MTCC 741 by agar streak dilution method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Access to a new class of biologically active quinoline based 1,2,4-triazoles. |
| AID369442 | Antibacterial activity against vancomycin-resistant Enterococcus faecium after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID352577 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 at 10 ug after 18 hrs by agar-well diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Synthesis of some new 1,2,4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities. |
| AID333998 | Antibacterial activity against Escherichia coli at 100 ug/100 uL after 24 hrs by tube broth dilution method | 1997 | Journal of natural products, Oct, Volume: 60, Issue:10 | New steroidal alkaloids from Buxus longifolia. |
| AID565747 | Antimicrobial activity against Enterococcus faecium clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID584304 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus vitulinus SVMP01 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID278238 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-2 acrAB::Kan with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID530236 | Resistance factor, ratio of MIC for Mycobacterium bovis BCG ML1034 to MIC for wild-type Mycobacterium bovis BCG | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1303896 | Antibacterial activity against multidrug resistant Enterobacter cloacae subsp. cloacae CDC 442-68 (ATCC 13047) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID1411619 | Bactericidal activity against Bacillus cereus incubated for 24 hrs followed by serial sub-cultivation and measured after 24 hrs by microdilution method | |||
| AID559347 | Antimicrobial activity against Salmonella spp. harboring oxa-2-like gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID300202 | Antibacterial activity against Escherichia coli ATCC 25922 at 200 mg/mL after 24 hrs by disc diffusion method | 2007 | Bioorganic & medicinal chemistry, Aug-15, Volume: 15, Issue:16 | Identification of antibacterial and antiviral activities of novel fused 1,2,4-triazine esters. |
| AID1596669 | Bactericidal activity against Bacillus cereus clinical isolate incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID1693216 | Anti-infective activity against Listeria monocytogenes NCTC 7973 assessed as reduction in bacterial growth by microdilution method | 2021 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 32 | 2-Aryl-3-(6-trifluoromethoxy)benzo[d]thiazole-based thiazolidinone hybrids as potential anti-infective agents: Synthesis, biological evaluation and molecular docking studies. |
| AID533422 | Antimicrobial activity against Anaerococcus prevotii by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID534939 | Antimicrobial activity against Desulfovibrio sp. by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID535215 | Antimicrobial activity against Clostridium subterminale by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID278271 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS38 tolC::Kan with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID585437 | Antimicrobial activity against ampG deficient Pseudomonas aeruginosa PAO1 harboring pZY0901 conferring resistance to gentamycin after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID529160 | Antibacterial activity against Pseudomonas aeruginosa 100609 after 20 hrs by broth microdilution assay in presence of 250 ug/ml polyethylenimine | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa. |
| AID1877439 | Antibacterial activity against Enterococcus hirae | 2022 | Bioorganic & medicinal chemistry letters, 01-01, Volume: 55 | New bis- and tetrakis-1,2,3-triazole derivatives: Synthesis, DNA cleavage, molecular docking, antimicrobial, antioxidant activity and acid dissociation constants. |
| AID521427 | Antibacterial activity against Stenotrophomonas maltophilia isolate KJ deficient in L2 beta lactamase gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Induction of L1 and L2 beta-lactamases of Stenotrophomonas maltophilia. |
| AID562812 | Antimicrobial activity against Escherichia coli DH5[alpha] | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID1060498 | Antibacterial activity against Staphylococcus aureus MTCC 96 by agar streak dilution method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Access to a new class of biologically active quinoline based 1,2,4-triazoles. |
| AID1769809 | Antimicrobial activity against Staphylococcus aureus Sau 745524 assessed as inhibition of bacterial growth incubated for 16 to 18 hrs by broth micro dilution technique | |||
| AID1408110 | Antifungal activity against Aspergillus flavus 3375 after 48 hrs by two-fold serial dilution method | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157 | Design, synthesis, antimicrobial, antiquorum-sensing and antitumor evaluation of new series of pyrazolopyridine derivatives. |
| AID324993 | Antibacterial activity against Haemophilus haemolyticus ATCC 33390 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID625290 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver fatty | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID1379751 | Antimicrobial activity against Bacillus cereus incubated for 24 hrs by serial dilution method | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of cyclopenta(hepta)[b]thiophene and fused cyclohepta[b]thiophene analogs. |
| AID65369 | In vitro antibacterial activity against ATCC 25922 strain of Escherichia coli | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID1368641 | Effect on cell viability of Pseudoalteromonas ulvae TC14 at 100 uM measured every hr during 6 hrs by resazurin based assay | 2018 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 28, Issue:2 | Towards smart biocide-free anti-biofilm strategies: Click-based synthesis of cinnamide analogues as anti-biofilm compounds against marine bacteria. |
| AID1143650 | Antibacterial activity against Enterococcus sp. ATCC 6589 assessed as growth inhibition by measuring turbidity of medium at 25 to 400 ug/mL measured over 10 hrs by microplate reader analysis | 2014 | European journal of medicinal chemistry, Jun-23, Volume: 81 | Synthesis of symmetrically substituted 3,3-dibenzyl-4-hydroxy-3,4-dihydro-1H-quinolin-2-ones, as novel quinoline derivatives with antibacterial activity. |
| AID565446 | Antimicrobial activity against Streptococcus intermedius SI006 biofilm harboring luxS mutant gene assessed as biofilm bacterial count at 0.02 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =413.7 +/- 24.47 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID1265201 | Bactericidal activity against Proteus vulgaris ATCC 13315 after 24 hrs | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes. |
| AID546959 | Antibacterial activity against Shigella dysenteriae assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1896848 | Antibacterial activity against Staphylococcus aureus ATCC25923 assessed as prevention of visible growth by broth microdilution method | |||
| AID557978 | Antimicrobial activity in Clostridium ramosum by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID559896 | Antimicrobial activity against Klebsiella oxytoca KO279 harboring beta-lactamase OXY-1 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | First detection of plasmid-encoded blaOXY beta-lactamase. |
| AID405301 | Antibacterial activity against beta-lactamase nonproducing ampicillin susceptible Haemophilus influenzae isolate by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID1132058 | Antiviral activity against Coxsackievirus B1 infected in human HeLa cells by agar diffusion assay | 1978 | Journal of medicinal chemistry, Jan, Volume: 21, Issue:1 | Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. |
| AID522367 | Antimicrobial activity against PpmrI knockout mutant Proteus mirabilis dIpc complemented with PPmrI gene after 16 to 18 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Proteus mirabilis pmrI, an RppA-regulated gene necessary for polymyxin B resistance, biofilm formation, and urothelial cell invasion. |
| AID547994 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237Y mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID1774182 | Antibacterial activity against Acinetobacter baumannii DSM30007 assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID572025 | Antibacterial activity against Clostridium clostridioforme by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID203441 | In vitro inhibitory activity against Staphylococci EryRc (23);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID351196 | Volume of distribution in neonates | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Pharmacokinetics of penicillin G in infants with a gestational age of less than 32 weeks. |
| AID1347491 | Antibacterial activity against Escherichia coli assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID633851 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID1279000 | Antibacterial activity against Escherichia coli incubated for 20 hrs by microbroth dilution method | 2016 | Bioorganic & medicinal chemistry, Mar-15, Volume: 24, Issue:6 | Synthesis of fluorinated carbazoles via C-H arylation catalyzed by Pd/Cu bimetal system and their antibacterial activities. |
| AID519114 | Antibacterial activity against Proteus mirabilis M 23 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID299667 | Antibacterial activity against Escherichia coli ATCC 25922 by broth microdilution method | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Synthesis and evaluation of amphiphilic cationic quinine-derived for antibacterial activity against methicillin-resistant Staphylococcus aureus. |
| AID573345 | Antibacterial activity against ceftazidime-nonsusceptible Citrobacter freundii assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1486832 | Antifungal activity against Aspergillus clavatus MTCC 1323 incubated for overnight by broth micro dilution method | 2017 | Bioorganic & medicinal chemistry, 08-01, Volume: 25, Issue:15 | 1,2,4-Triazole and 1,3,4-oxadiazole analogues: Synthesis, MO studies, in silico molecular docking studies, antimalarial as DHFR inhibitor and antimicrobial activities. |
| AID565013 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus simulans assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID572232 | Antibacterial activity against Ruminococcus albus by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID395730 | Antimicrobial activity against imipenem-resistant invasive nontypeable Haemophilus influenzae isolate 183 by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | First characterization of heterogeneous resistance to imipenem in invasive nontypeable Haemophilus influenzae isolates. |
| AID759380 | Antibacterial activity against Serratia marcescens IMRU 70 assessed as growth inhibition after 24 hrs by Kirby-Bauer disc diffusion method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis and biological evaluation of some novel thiazole compounds as potential anti-inflammatory agents. |
| AID644166 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID534945 | Antimicrobial activity against Fusobacterium necrophorum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID420212 | Antimicrobial activity against Staphylococcus aureus UFPEDA 01 after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID572254 | Antibacterial activity against Bilophila wadsworthia by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID665061 | Antibacterial activity against Escherichia coli MTCC 443 after 24 hrs by micro-broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 22, Issue:11 | An efficient one-pot synthesis, structure, antimicrobial and antioxidant investigations of some novel quinolyldibenzo[b,e][1,4]diazepinones. |
| AID1159103 | Antimicrobial activity against Bacillus subtilis ATCC 6633 assessed as zone of inhibition at 10 mg by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID534942 | Antimicrobial activity against Fusobacterium mortiferum by Wadsworth agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID666963 | Antibacterial activity against Vibrio cholerae MTCC 3906 by broth microdilution method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | New N-arylamino biquinoline derivatives: synthesis, antimicrobial, antituberculosis, and antimalarial evaluation. |
| AID528720 | Antibacterial activity against vancomycin resistant Enterococcus faecalis VanB clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID522388 | Activity of Aeromonas enteropelogenes Beta-lactamase TRU1 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Genetic and biochemical characterization of TRU-1, the endogenous class C beta-lactamase from Aeromonas enteropelogenes. |
| AID564824 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID555228 | Ratio of Kcat to Km for Acinetobacter genomosp. 3 isolate 195 ADC-18 | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID207967 | Minimum inhibitory concentration of Ampicillin required for growth inhibition of Beta lactamase producing bacteria Staphylococcus aureus (S-54K) | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8 | Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives. |
| AID555460 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 65 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1286498 | Bactericidal activity against methicillin-sensitive Staphylococcus aureus ATCC 6538 after 24 and 48 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID405309 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae isolate assessed as percent susceptible isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID573349 | Antibacterial activity against ceftazidime-nonsusceptible Enterobacter cloacae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID678545 | Antibacterial activity against ampicillin-resistant Escherichia coli clinical isolate | 2012 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 22, Issue:18 | Design, solvent free synthesis, and antimicrobial evaluation of 1,4 dihydropyridines. |
| AID543811 | Bactericidal activity against Staphylococcus aureus ATCC 29213 assessed as eradication of pre-formed biofilm at 50 times MIC after 24 hrs by serial dilution | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID1604668 | Antibacterial activity against Enterococcus faecalis ATCC 29212 by visual method | |||
| AID379648 | Antibacterial activity against Micrococcus flavus SBUG 16 after 18 hrs by broth microdilution method | 2000 | Journal of natural products, Mar, Volume: 63, Issue:3 | Ganomycins A and B, new antimicrobial farnesyl hydroquinones from the basidiomycete Ganoderma pfeifferi. |
| AID1323305 | Antibacterial activity against Salmonella enterica ATCC 14028 after 24 hrs by serial two fold dilution method | 2016 | Journal of natural products, 07-22, Volume: 79, Issue:7 | Actinomadurol, an Antibacterial Norditerpenoid from a Rare Actinomycete, Actinomadura sp. KC 191. |
| AID70153 | Minimum inhibitory concentration against 30 strains of Escherichia coli | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8 | Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives. |
| AID535223 | Antimicrobial activity against Actinomyces odontolyticus by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID533880 | Antibacterial activity against cefotaxime-intermediate Streptococcus pneumoniae isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro activity of ceftaroline against Streptococcus pneumoniae isolates exhibiting resistance to penicillin, amoxicillin, and cefotaxime. |
| AID534379 | Antibacterial activity against Citrobacter freundii KHM243 clinical isolate by microdilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate. |
| AID429365 | Antibacterial activity against Staphylococcus aureus after 24 hrs by liquid dilution method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents. |
| AID572039 | Antibacterial activity against Clostridium hypermegas by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID471908 | Antibacterial activity against Escherichia coli MTCC 41 at 128 ug/ml after 16 hrs by disc diffusion method | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | A facile one-pot green synthesis and antibacterial activity of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes. |
| AID584762 | Antimicrobial activity against Acinetobacter lwoffii isolate A expressing beta-lactamase OXA-164 isolated from tracheal secretion of patient in presence of Sulbactam by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID559580 | Antimicrobial activity against Chlamydia trachomatis infected in Vero cells | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic susceptibility of Waddlia chondrophila in Acanthamoeba castellanii amoebae. |
| AID572264 | Antibacterial activity against Prevotella loescheii by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1331875 | Antibacterial activity against Escherichia coli MC1061 | 2017 | Bioorganic & medicinal chemistry, 01-01, Volume: 25, Issue:1 | Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. |
| AID1411629 | Bactericidal activity against Enterobacter cloacae incubated for 24 hrs followed by serial sub-cultivation and measured after 24 hrs by microdilution method | |||
| AID564829 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus sciuri after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID255531 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 16.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID278251 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS1 tolC::Kan with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID425603 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM580 in mouse J774A1 cells isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as intracellular killing of bacteria at 10% compound Cmax a | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID448154 | Antimicrobial activity against Candida tropicalis ATCC 13803 at 10 ug after 18 hrs by well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis of some new 1,2,4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities. |
| AID372549 | Antibacterial activity against genetically beta-lactamase-negative ampicillin-resistant Haemophilus influenzae type b with an amino acid substitution in highly mutated locus Ser-385 of ftsI gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID563975 | Ratio of Kcat to Km for Klebsiella pneumoniae 05-560 beta-lactamase IMP1 | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. |
| AID324982 | Antibacterial activity against Haemophilus influenzae MSC02149 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID533634 | Antimicrobial activity against Propionibacterium acnes assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID278258 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS9 acrAB::Kan with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1225331 | Antimicrobial activity against Salmonella typhimurium incubated for 24 hrs | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Alkaloidal metabolites from a marine-derived Aspergillus sp. fungus. |
| AID1596668 | Antibacterial activity against Bacillus cereus clinical isolate after 24 hrs by iodonitrotetrazolium chloride dye based microdilution assay | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID562810 | Antimicrobial activity against Escherichia coli J53 harboring pEK499 plasmid encoding CTX-M extended-spectrum beta-lactamases | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID567472 | Antimicrobial activity against gBLNAR Haemophilus influenzae by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | In vitro activity of tebipenem, a new oral carbapenem antibiotic, against beta-lactamase-nonproducing, ampicillin-resistant Haemophilus influenzae. |
| AID324228 | Antibacterial activity against Escherichia coli K12 containing PhoU mutant assessed as cell count in log phase at 100 ug/ml after 5 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID495348 | Antimicrobial activity against Beta-lactamase-positive, ampicillin-cluvulanate-resistant Haemophilus influenzae with Ile449Val, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID529574 | Antimicrobial activity against Escherichia coli DH5alpha harboring plasmid BC-SK after 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora. |
| AID625288 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for jaundice | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID561937 | Antibacterial activity against blaOXA-24-positive Acinetobacter baumannii isolate N50 by CLSI broth microdilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Characterization of pABVA01, a plasmid encoding the OXA-24 carbapenemase from Italian isolates of Acinetobacter baumannii. |
| AID529611 | Antibacterial activity against Beta-lactamase negative Haemophilus influenzae assessed as resistant isolates after 20 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID529159 | Antibacterial activity against Pseudomonas aeruginosa 100609 after 20 hrs by broth microdilution assay | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa. |
| AID511060 | Antibacterial activity against Staphylococcus aureus MTCC 96 by broth microdilution method | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Pharmacological evaluation and characterizations of newly synthesized 1,2,4-triazoles. |
| AID1457522 | Antibacterial activity against Bacillus subtilis assessed as inhibition of protein synthesis at 2 mg/L after 50 mins by [35S]-methionine incorporation assay | 2017 | Journal of medicinal chemistry, 07-27, Volume: 60, Issue:14 | Lipophosphonoxins II: Design, Synthesis, and Properties of Novel Broad Spectrum Antibacterial Agents. |
| AID1433839 | Antibacterial activity against Vibrio cholerae MTCC 3906 after 24 to 48 hrs by broth microdilution method | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs. |
| AID584302 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus sciuri subsp. sciuri ATCC 29062T by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID557752 | Antimicrobial activity in Lactobacillus by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID511059 | Antibacterial activity against Streptococcus pyogenes MTCC 442 by broth microdilution method | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Pharmacological evaluation and characterizations of newly synthesized 1,2,4-triazoles. |
| AID1399273 | Antimicrobial activity against Escherichia coli isolate SJ 1 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID520709 | Antibacterial activity against Acinetobacter baumannii MAD by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID573369 | Antibacterial activity against ceftazidime-susceptible Proteus mirabilis assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1382102 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 after 18 to 24 hrs by double microdilution method | 2018 | European journal of medicinal chemistry, Feb-25, Volume: 146 | Ciprofloxacin derivatives and their antibacterial activities. |
| AID1322098 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 after 24 hrs by broth microdilution assay | 2016 | Bioorganic & medicinal chemistry, 11-01, Volume: 24, Issue:21 | Synthesis, characterization, and evaluation of (E)-methyl 2-((2-oxonaphthalen-1(2H)-ylidene)methylamino)acetate as a biological agent and an anion sensor. |
| AID585396 | Ratio of Kcat to Km for Bradyrhizobium japonicum metallo-beta-lactamase BJP-1 | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides. |
| AID1617940 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 16 to 48 hrs | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12 | Structure Determination, Functional Characterization, and Biosynthetic Implications of Nybomycin Metabolites from a Mining Reclamation Site-Associated |
| AID529573 | Antimicrobial activity against Escherichia coli DH5alpha harboring plasmid pLBII carrying beta-lactamase CAR-1 gene after 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora. |
| AID546927 | Antibacterial activity against Salmonella enterica serovar Enteritidis by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID324994 | Antibacterial activity against Haemophilus parainfluenzae ATCC 33392 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID448151 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 at 10 ug after 18 hrs by well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis of some new 1,2,4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities. |
| AID1272235 | Antibacterial activity against Escherichia coli by broth micro-dilution method | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3 | Efficiently functionalized oxacalix[4]arenes: Synthesis, characterization and exploration of their biological profile as novel HDAC inhibitors. |
| AID514125 | Antibacterial activity against clinical isolate of Staphylococcus aureus assessed as growth inhibition at 1 mg/ml after 16 to 20 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays. |
| AID519990 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecalis nosocomial isolate | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID535205 | Antimicrobial activity against Clostridium septicum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID555223 | Activity of Acinetobacter genomosp. 3 isolate 65 ADC-14 | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID557716 | Antimicrobial activity in Fusobacterium necrophorum by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID495323 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID1591744 | Antifungal activity against Candida albicans MTCC 227 after 72 hrs by serial dilution method | 2019 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 29, Issue:16 | Rational design, molecular docking and synthesis of novel homopiperazine linked imidazo[1,2-a]pyrimidine derivatives as potent cytotoxic and antimicrobial agents. |
| AID585835 | Antimicrobial activity against ampD, ampDh2, ampDh3 and ampGh1 deficient Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID324226 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 assessed as cell count in log phase at 100 ug/ml after 5 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID573383 | Antibacterial activity against beta lactamase-positive Haemophilus influenzae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID655697 | Antibacterial activity against Staphylococcus aureus ATCC 11632 at 160 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID1870155 | Antibacterial activity against wild type Staphylococcus aureus 4502/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID289619 | Antibacterial activity against Staphylococcus aureus after 24 hrs by micro-broth dilution technique | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, in vitro antibacterial and antifungal evaluations of 2-amino-4-(1-naphthyl)-6-arylpyrimidines. |
| AID1224743 | Antimicrobial activity against Aspergillus fumigatus MTCC 3008 by broth microdilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Ultrasound-assisted one-pot four-component synthesis of novel 2-amino-3-cyanopyridine derivatives bearing 5-imidazopyrazole scaffold and their biological broadcast. |
| AID1870149 | Antibacterial activity against wild type Staphylococcus aureus 4504/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID456086 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID318665 | Antibacterial activity against Propionibacterium granulosum GAI 7414 by broth microdilution method | 2008 | Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7 | Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens. |
| AID575170 | Inhibition of acrAB AcrAB-TolC-mediated Nile Red efflux in Escherichia coli K-12 3-AG100 overexpressing acrAB AcrAB-TolC assessed as time needed for 50% efflux after energization with 50 mM glucose at 200 uM by spectrofluorometric assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. |
| AID546958 | Antibacterial activity against Shigella dysenteriae assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1382085 | Antibacterial activity against Mycobacterium smegmatis ATCC 607 after 48 to 72 hrs by double microdilution method | 2018 | European journal of medicinal chemistry, Feb-25, Volume: 146 | Ciprofloxacin derivatives and their antibacterial activities. |
| AID1286511 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolate after 20 to 24 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID564885 | Antibacterial activity against wild-type Escherichia coli AG100 harboring IS186 insertion in lon3 gene, Tn5 insertion in ycgE gene, plasmid pET21b carrying ompF gene and pACT7SP at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID1225330 | Antimicrobial activity against Micrococcus luteus incubated for 24 hrs | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Alkaloidal metabolites from a marine-derived Aspergillus sp. fungus. |
| AID324224 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoU mutant assessed as cell count in log phase at 100 ug/ml after 3 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID546954 | Antibacterial activity against Shigella boydii by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID534392 | Antibacterial activity against Escherichia coli JM109 by microdilution method in presence of Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate. |
| AID1334268 | Antibacterial activity against Staphylococcus aureus | 2017 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 27, Issue:2 | New bithiazolyl hydrazones: Novel synthesis, characterization and antitubercular evaluation. |
| AID567771 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 assessed as >99.9 % reduction in CFU after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID1504824 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 6358 after 24 hrs by broth microdilution method | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12 | Sulfur-Containing Aristoloxazines and Other Constituents of the Roots of Aristolochia orbicularis. |
| AID585431 | Antimicrobial activity against oqxAB positive Escherichia coli C600 D83-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1139538 | Antibacterial activity against Escherichia coli DH5alpha expressing beta-lactamase SHV-5 by CLSI broth microdilution method | 2014 | Journal of medicinal chemistry, May-08, Volume: 57, Issue:9 | Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. |
| AID1185701 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by agar dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | New thiophene-1,2,4-triazole-5(3)-ones: highly bioactive thiosemicarbazides, structures of Schiff bases and triazole-thiols. |
| AID1577947 | Antimicrobial activity against Pseudomonas aeruginosa KW799 under iron-deficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID352615 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 by tube dilution method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Synthesis and in vitro antimicrobial activity of some novel substituted benzimidazole derivatives having potent activity against MRSA. |
| AID1496310 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis 368 after 24 hrs | 2018 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 28, Issue:12 | In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci. |
| AID330985 | Antimicrobial activity against Staphylococcus epidermis | 2007 | Nature, May-03, Volume: 447, Issue:7140 | PTC124 targets genetic disorders caused by nonsense mutations. |
| AID519113 | Antibacterial activity against Proteus mirabilis M 21 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID1627301 | Antifungal activity against Candida albicans ATCC 10231 by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16 | New antibacterial agents: Hybrid bioisoster derivatives as potential E. coli FabH inhibitors. |
| AID447437 | Antibacterial activity against Klebsiella pneumoniae ATCC 11298 at 100 ug/ml after 24 hrs by agar cup plate method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and antibacterial activity of 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-pyrazol-4-yl]-5-(substituted-phenyl)-[1,3,4]oxadiazoles. |
| AID532981 | Antibacterial activity against Escherichia coli DH5alpha | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID278531 | Antimicrobial activity against Bifidobacterium pseudolongum ATCC 25562 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID421838 | Antibacterial activity against Proteus vulgaris ATCC 3851 | 2009 | Journal of natural products, Feb-27, Volume: 72, Issue:2 | Glionitrin A, an antibiotic-antitumor metabolite derived from competitive interaction between abandoned mine microbes. |
| AID383173 | Antimicrobial activity against Staphylococcus aureus ATCC 65389 | 2008 | Journal of natural products, Apr, Volume: 71, Issue:4 | Sesterterpenoids from the sponge Sarcotragus sp. |
| AID543808 | Bactericidal activity against Klebsiella pneumoniae VT 1367 assessed as eradication of pre-formed biofilm at 50 times MIC after 24 hrs by serial dilution | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID565427 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 assessed as biofilm formation at 0.04 to 0.10 ug/ml | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID325445 | Antibacterial activity against Escherichia coli C921-61 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID546944 | Antibacterial activity against Salmonella enterica serovar Virchow assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID532676 | Antimicrobial activity against ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates assessed as susceptible isolates by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. |
| AID1527492 | Antimicrobial activity against multi drug-resistant Klebsiella pneumoniae assessed as reduction in microbial growth by two-fold serial dilution method | 2020 | European journal of medicinal chemistry, Jan-01, Volume: 185 | Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents. |
| AID1585547 | Antibacterial activity against Escherichia coli assessed as zone of inhibition at 1 mg/ml after 32 hrs by agar-well diffusion method | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Benzofuran derivatives and their anti-tubercular, anti-bacterial activities. |
| AID1694057 | Antibacterial activity against Bacillus cereus UW85 assessed as reduction in bacterial growth incubated for 18 hrs by two-fold serial dilution method | 2021 | Bioorganic & medicinal chemistry, 02-01, Volume: 31 | Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study. |
| AID477751 | Antimicrobial activity against Staphylococcus aureus after 24 hrs | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | An eco-friendly synthesis and antimicrobial activities of dihydro-2H-benzo- and naphtho-1,3-oxazine derivatives. |
| AID559334 | Antimicrobial activity against Shigella flexneri harboring tem-like gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID632562 | Antibacterial activity against Proteus vulgaris at 200 ug/mL after 24 hrs by agar cup diffusion method | 2011 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 21, Issue:24 | A new antifungal briarane diterpenoid from the gorgonian Junceella juncea Pallas. |
| AID544282 | Antimicrobial activity against Enterococcus faecalis NKH12 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID546923 | Antibacterial activity against Escherichia coli assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID555270 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 195 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID585848 | Antimicrobial activity against Pseudomonas aeruginosa isolate 4 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID276386 | Antibacterial activity against Pseudomonas aeruginosa by broth microdilution technique | 2006 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 16, Issue:22 | Naphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: synthesis and biological evaluation as potential antibacterial and antifungal agents. |
| AID255560 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 16.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID528740 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae ATCC BAA-611 harboring PBP-2X Q557E mutant gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID622562 | Antimicrobial activity against Escherichia coli MTCC 443 for 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 21, Issue:20 | Microwave assisted synthesis and antimicrobial evaluation of new fused pyran derivatives bearing 2-morpholinoquinoline nucleus. |
| AID542766 | Antimicrobial activity against Escherichia coli PA11 expressing aac(6')-Ib-cr, qnrS1 and qepA genes by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID1535455 | Growth inhibition of Paracoccus sp. 4M6 at 5 uM measured every hr for 6 hrs by turbidimetric method | 2019 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 29, Issue:4 | Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds? |
| AID447062 | Antibacterial activity against Escherichia coli ATCC 11230 at 10 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID533129 | Antimicrobial activity against Bacteroides caccae by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID535243 | Antimicrobial activity against Bifidobacterium pseudolongum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID547178 | Antibacterial activity against Vibrio parahaemolyticus assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID530288 | Antimicrobial activity against PR-39-resistant Salmonella enterica serovar Typhimurium LT2 DA6192 by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2. |
| AID655705 | Antibacterial activity against Staphylococcus aureus ATCC 11632 after 24 hrs by serial broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID1896846 | Antibacterial activity against methicillin-resistant Staphylococcus aureus R3708 assessed as prevention of visible growth by broth microdilution method | |||
| AID533388 | Antimicrobial activity against Clostridium difficile assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID1331870 | Antibacterial activity against Listeria monocytogenes ATCC 19115 | 2017 | Bioorganic & medicinal chemistry, 01-01, Volume: 25, Issue:1 | Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. |
| AID318667 | Antibacterial activity against Mycoplasma pneumoniae Mac by broth microdilution method | 2008 | Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7 | Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens. |
| AID1306202 | Antibacterial activity against Escherichia coli ATCC 25922 after 18 hrs by microbroth dilution assay | 2016 | Bioorganic & medicinal chemistry, 07-15, Volume: 24, Issue:14 | The influence of halogen substituents on the biological properties of sulfur-containing flavonoids. |
| AID1693214 | Anti-infective activity against Pseudomonas aeruginosa ATCC 27853 assessed as reduction in bacterial growth by microdilution method | 2021 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 32 | 2-Aryl-3-(6-trifluoromethoxy)benzo[d]thiazole-based thiazolidinone hybrids as potential anti-infective agents: Synthesis, biological evaluation and molecular docking studies. |
| AID539560 | Antimicrobial activity against Micrococcus luteus IFC 12708 | 2010 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 20, Issue:23 | Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase. |
| AID1591741 | Antibacterial activity against Bacillus megaterium MTCC 428 after 24 hrs by serial dilution method | 2019 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 29, Issue:16 | Rational design, molecular docking and synthesis of novel homopiperazine linked imidazo[1,2-a]pyrimidine derivatives as potent cytotoxic and antimicrobial agents. |
| AID535747 | Antimicrobial activity against community-acquired Escherichia coli obtained from patient with intra-abdominal infection assessed as susceptible isolates by EUCAST method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Incidence and antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae with extended-spectrum beta-lactamases in community- and hospital-associated intra-abdominal infections in Europe: results of the 2008 Study for Monitoring Antimicrob |
| AID544283 | Antimicrobial activity against Enterococcus faecalis NKH13 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID521436 | Ratio of induction of xylE gene expression in Stenotrophomonas maltophilia isolate KJ deficient in L1 beta lactamase gene to induction of xylE gene expression in Stenotrophomonas maltophilia isolate KJ deficient in L2 beta lactamase gene assessed as catec | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Induction of L1 and L2 beta-lactamases of Stenotrophomonas maltophilia. |
| AID555478 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 14 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1156858 | Antimicrobial activity against Klebsiella pneumoniae ATCC 27736 after 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents. |
| AID1493669 | Antimicrobial activity against Staphylococcus aureus RCMB 010027 after overnight incubation by macro-tube dilution technique | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Quinoline derivatives bearing pyrazole moiety: Synthesis and biological evaluation as possible antibacterial and antifungal agents. |
| AID494536 | Antimicrobial activity against Proteus vulgaris NCIM 2813 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID494536 | Antimicrobial activity against Proteus vulgaris NCIM 2813 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May-06 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID655698 | Antibacterial activity against Staphylococcus aureus ATCC 11632 at 80 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID1604671 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 by visual method | |||
| AID1652707 | Induction of Escherichia coli K12 MG1655 lexA promotor measured at 30 mins interval for 20 hrs by fluorescence assay relative to control | |||
| AID519992 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecium nosocomial isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID558536 | Antibacterial activity against bla gene-negative and nitrocefin reaction-positive beta-lactamase harboring Campylobacter jejuni isolate P854 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID685140 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by broth microdilution method | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Micelles catalyzed chemo- and regio-selective one pot and one step synthesis of 2,3,5,6-tetrakis(alkyl and arylsulfanyl)-1,4-benzoquinones and 2,5-diaminosubstituted-1,4-benzoquinones "In-Water" and their biological evaluation as antibacterial and antifun |
| AID563969 | Antibacterial activity against Escherichia coli J53 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. |
| AID1412921 | Antibacterial activity against Bacillus cereus clinical isolate by microdilution method | 2018 | MedChemComm, May-01, Volume: 9, Issue:5 | Design, synthesis and antimicrobial activity of usnic acid derivatives. |
| AID546962 | Antibacterial activity against Yersinia enterocolitica assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID561936 | Antibacterial activity against blaOXA-24-positive Acinetobacter baumannii isolate RUH134 by CLSI broth microdilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Characterization of pABVA01, a plasmid encoding the OXA-24 carbapenemase from Italian isolates of Acinetobacter baumannii. |
| AID565667 | Antimicrobial activity against beta-lactamase positive (amoxicillin)clavulanate-resistant Haemophilus influenzae by broth microdilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID1287513 | Antibacterial activity against Escherichia coli NCIM 2688 after 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 26, Issue:7 | Synthesis, biological evaluation and molecular docking study of some novel indole and pyridine based 1,3,4-oxadiazole derivatives as potential antitubercular agents. |
| AID555241 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 52 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID633857 | Antibacterial activity against clinical isolate of Bacillus cereus incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID285522 | Antibacterial activity against Haemophilus influenzae after 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens. |
| AID419338 | Antibacterial activity against Escherichia coli ATCC 25922 at 500 ug/ml after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis and evaluation of some new benzimidazole derivatives as potential antimicrobial agents. |
| AID557708 | Antimicrobial activity in Porphyromonas asaccharolytica by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1139537 | Antibacterial activity against Escherichia coli DH5alpha harboring pUCP26 empty vector by CLSI broth microdilution method | 2014 | Journal of medicinal chemistry, May-08, Volume: 57, Issue:9 | Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. |
| AID1385486 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolate shhs-A1 by two-fold serial dilution method | 2018 | Journal of natural products, 08-24, Volume: 81, Issue:8 | Abyssomicin Monomers and Dimers from the Marine-Derived Streptomyces koyangensis SCSIO 5802. |
| AID372556 | Antibacterial activity against genetically beta-lactamase-positive amoxicillin-clavulanate-resistant Haemophilus influenzae type b with an amino acid substitution in variable mutated locus Asn-526 or Arg-517 of ftsI gene assessed as susceptibility rate by | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID245375 | Minimum inhibitory concentration required for antibacterial activity against Staphylococcus aureus ATCC 2943; gram positive | 2004 | Bioorganic & medicinal chemistry letters, Aug-16, Volume: 14, Issue:16 | Synthesis and QSAR studies of pyrimido[4,5-d]pyrimidine-2,5-dione derivatives as potential antimicrobial agents. |
| AID1185699 | Antimicrobial activity against Yersinia pseudotuberculosis ATCC 911 after 24 hrs by agar dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | New thiophene-1,2,4-triazole-5(3)-ones: highly bioactive thiosemicarbazides, structures of Schiff bases and triazole-thiols. |
| AID334244 | Antimicrobial activity against Bacillus subtilis NCTC 10073 after 24 hrs by microdilution technique | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4 | Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline. |
| AID770911 | Antibacterial activity against Escherichia coli IFO 3301 assessed as growth inhibition at 100 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID526302 | Antimicrobial activity against Staphylococcus aureus by agar plate disk diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Bernthsen synthesis, antimicrobial activities and cytotoxicity of acridine derivatives. |
| AID731205 | Antibacterial activity against Clostridium tetani MTCC 449 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles. |
| AID448155 | Antimicrobial activity against Candida albicans ATCC 60193 at 10 ug after 18 hrs by well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis of some new 1,2,4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities. |
| AID1399259 | Antimicrobial activity against Streptococcus pyogenes ATCC 700294 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID318720 | Antimicrobial activity against Aspergillus niger ATCC 6275 upto 100 ug/ml by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID625287 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatomegaly | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID363844 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs by macro broth dilution assay | 2008 | European journal of medicinal chemistry, Jul, Volume: 43, Issue:7 | Synthesis, potent anti-staphylococcal activity and QSARs of some novel 2-anilinobenzazoles. |
| AID1907032 | Antibacterial activity against Pseudomonas aeruginosa ATCC27853 strain assessed as inhibition of bacterial growth incubated for 8 hrs by CLSI protocol based microdilution assay | 2022 | Journal of medicinal chemistry, 04-14, Volume: 65, Issue:7 | Design, Synthesis, and Proof-of-Concept of Triple-Site Inhibitors against Aminoacyl-tRNA Synthetases. |
| AID420217 | Antimicrobial activity against Candida albicans UFPEDA 1007 after 48 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID555221 | Antibacterial activity against Escherichia coli DH5alpha carrying ampC gene of Acinetobacter genomosp. 3 isolate 109 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1546105 | Antimicrobial activity against Bacillus subtilis | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID203443 | In vitro inhibitory activity against Staphylococci EryRi (65);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID424706 | Antibacterial activity against Escherichia coli at 1 ug/disk | 2009 | Journal of natural products, Apr, Volume: 72, Issue:4 | Limazepines A-F, pyrrolo[1,4]benzodiazepine Antibiotics from an Indonesian Micrococcus sp. |
| AID545436 | Antimicrobial activity against extended-spectrum beta-lactamase-positive Escherichia coli obtained from patient with complicated intra-abdominal infection assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhib | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID1733174 | Antibacterial activity against Escherichia coli assessed as bacterial growth inhibition measured after 24 hrs by broth dilution assay | 2021 | Bioorganic & medicinal chemistry letters, 05-01, Volume: 39 | Synthesis and antibacterial activities of marine natural product ianthelliformisamines and subereamine synthetic analogues. |
| AID1235343 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as zone of inhibition at 2862 uM incubated overnight at 37 degC | 2015 | Journal of natural products, Jul-24, Volume: 78, Issue:7 | Phytochemical Investigation of the Constituents Derived from the Australian Plant Macropidia fuliginosa. |
| AID555456 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 56 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID567776 | Antimicrobial activity against Klebsiella pneumoniae ATCC 13883 assessed as >99.9 % reduction in CFU after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID585856 | Antimicrobial activity against Pseudomonas aeruginosa isolate 8 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID582908 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87Y mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID717346 | Antimicrobial activity against Escherichia coli ATCC 35270 after 24 hrs | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12 | Brominated aromatic furanones and related esters from the ascidian Synoicum sp. |
| AID372777 | Antibacterial activity against genetically beta-lactamase-positive amoxicillin-clavulanate-resistant Haemophilus influenzae type b with an amino acid substitution in highly mutated locus Ser-385 of ftsI gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID558336 | Antibacterial activity against bla gene-positive and nitrocefin reaction-positive beta-lactamase harboring Campylobacter jejuni isolate P1618 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID559578 | Antimicrobial activity against Waddlia chondrophila ATCC VR-1470 infected in Vero cells | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic susceptibility of Waddlia chondrophila in Acanthamoeba castellanii amoebae. |
| AID601602 | Antibacterial activity against Kocuria sp. isolate Fs24 at 10 ug/disk after 24 hrs by disc diffusion assay | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Synthesis of 2-aziridinyl phosphonates by modified Gabriel-Cromwell reaction and their antibacterial activities. |
| AID1868101 | Antibacterial activity against Micrococcus luteus ATCC 9341 assessed as inhibition of visible bacterial growth incubated for 18 hrs by CLSI protocol based assay | 2022 | Journal of natural products, 05-27, Volume: 85, Issue:5 | Enceleamycins A-C, Furo-Naphthoquinones from |
| AID527633 | Antimicrobial activity against Salmonella Typhimurium ATCC 14028 after 24 hrs by broth dilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Bromophenols as Candida albicans isocitrate lyase inhibitors. |
| AID289623 | Antifungal activity against Trichophyton tonsurans after 7 days | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, in vitro antibacterial and antifungal evaluations of 2-amino-4-(1-naphthyl)-6-arylpyrimidines. |
| AID544277 | Antimicrobial activity against Enterococcus faecalis NKH7 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1331878 | Antibacterial activity against Salmonella enterica ATCC 14028 | 2017 | Bioorganic & medicinal chemistry, 01-01, Volume: 25, Issue:1 | Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. |
| AID555666 | Antimicrobial activity against Escherichia coli DH10B harboring natural plasmid pWES-1 carrying CTX-M-53 gene by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg. |
| AID572248 | Antibacterial activity against Parabacteroides merdae by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1693220 | Anti-infective activity against Salmonella typhimurium ATCC 13311 assessed as reduction in bacterial growth by microdilution method | 2021 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 32 | 2-Aryl-3-(6-trifluoromethoxy)benzo[d]thiazole-based thiazolidinone hybrids as potential anti-infective agents: Synthesis, biological evaluation and molecular docking studies. |
| AID534951 | Antimicrobial activity against Porphyromonas sp. by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID568343 | Antimicrobial activity against wild type Stenotrophomonas maltophilia by broth dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 21, Issue:4 | Design and synthesis of potent Gram-negative specific LpxC inhibitors. |
| AID622557 | Antimicrobial activity against Streptococcus pneumoniae MTCC 1936 for 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 21, Issue:20 | Microwave assisted synthesis and antimicrobial evaluation of new fused pyran derivatives bearing 2-morpholinoquinoline nucleus. |
| AID555226 | Ratio of Kcat to Km for Acinetobacter genomosp. 3 isolate 103 ADC-16 | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID775964 | Antibacterial activity against Bacillus subtilis ATCC 6633 assessed as growth inhibition at 100 ug/mL after 18 to 24 hrs by microdilution assay | 2013 | European journal of medicinal chemistry, Nov, Volume: 69 | Synthesis, antibacterial and antioxidant activities of new 1-alkyl-4-(1-alkyl-4-oxo-1,4-dihydroquinolin-2-yl)pyridinium bromides. |
| AID585441 | Antimicrobial activity against ampG deficient Pseudomonas aeruginosa PAK after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID287242 | Antimicrobial activity against Pseudomonas aeruginosa IFO 3448 at 200 ug/disc | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles. |
| AID1577957 | Antimicrobial activity against Escherichia coli ATCC 25922 under iron-deficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID509323 | Antibacterial activity against Staphylococcus aureus MTCC 1144 at 64 mg/ml after 16 hrs by disk diffusion test | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antiviral and antibacterial agents. |
| AID529898 | Antimicrobial activity against Leptospira weilii isolate 6 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID1228009 | Antimicrobial activity against Staphylococcus epidermidis CMCC 26069 assessed as complete prevention of visible growth after incubation at 37 degC for 18 to 20 hrs | 2015 | Journal of natural products, Apr-24, Volume: 78, Issue:4 | Antibacterial Biphenanthrenes from the Fibrous Roots of Bletilla striata. |
| AID545145 | Ratio of Kcat to Km of CMY-2 by spectrophotometry | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids. |
| AID1774190 | Antibacterial activity against Escherichia coli delta fepA delta cirA assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID1907018 | Antibacterial activity against Escherichia coli ATCC 25922 strain assessed as inhibition of bacterial growth incubated for 8 hrs by CLSI protocol based microdilution assay | 2022 | Journal of medicinal chemistry, 04-14, Volume: 65, Issue:7 | Design, Synthesis, and Proof-of-Concept of Triple-Site Inhibitors against Aminoacyl-tRNA Synthetases. |
| AID583084 | Activity of Escherichia coli BL21(DE3) VIM-2 W87F mutant beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID775559 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus 63718 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21 | New derivatives of salicylamides: Preparation and antimicrobial activity against various bacterial species. |
| AID324160 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 after 16 hrs by serial dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1433836 | Antibacterial activity against Clostridium tetani MTCC 449 after 24 to 48 hrs by broth microdilution method | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs. |
| AID551093 | Antibacterial activity against Staphylococcus aureus by liquid dilution method | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1 | 3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents. |
| AID585849 | Antimicrobial activity against Pseudomonas aeruginosa isolate 5 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID252619 | Mean lysis diameter was measured against Enterobacter aerogenes EA289 with D121A mutation by standard disk diffusion method on MH agar | 2005 | Journal of medicinal chemistry, Mar-10, Volume: 48, Issue:5 | Beta-lactam screening by specific residues of the OmpF eyelet. |
| AID533414 | Antimicrobial activity against Peptoniphilus asaccharolyticus by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID1491152 | Antibacterial activity against Bacillus thuringiensis BT01 by CLSI method | 2017 | Journal of natural products, 05-26, Volume: 80, Issue:5 | Antimicrobial Spirotetronate Metabolites from Marine-Derived Micromonospora harpali SCSIO GJ089. |
| AID442410 | Antimicrobial activity against Staphylococcus aureus at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID509704 | Antibacterial activity against Salmonella typhi after 24 hrs by tube dilution method | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of some 3-substituted amino-4,5-tetramethylene thieno[2,3-d][ 1,2,3]-triazin-4(3H)-ones as potential antimicrobial agents. |
| AID1870157 | Antibacterial activity against wild type Staphylococcus aureus 5079/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID582922 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61V mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID573346 | Antibacterial activity against ceftazidime-susceptible Enterobacter cloacae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID533404 | Antimicrobial activity against Clostridium subterminale assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID1769808 | Antimicrobial activity against Staphylococcus aureus Sau 718306 assessed as inhibition of bacterial growth incubated for 16 to 18 hrs by broth micro dilution technique | |||
| AID633855 | Antibacterial activity against Enterococcus faecalis isolated from human after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID638580 | Antibacterial activity against Xanthomonas oryzae pv. oryzae XKK.12 assessed as growth inhibition at 5.7 X 10'-3 M measured after 1 to 2 days | 2011 | Journal of natural products, Dec-27, Volume: 74, Issue:12 | In vitro antibacterial activity of sphaeropsidins and chemical derivatives toward Xanthomonas oryzae pv. oryzae, the causal agent of rice bacterial blight. |
| AID66556 | In vitro inhibitory activity against enterococci EryRi (19);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID736394 | Antibacterial activity against Escherichia coli 6r3 by paper disk diffusion method | 2013 | Journal of natural products, Jan-25, Volume: 76, Issue:1 | Antibacterial and antiplasmodial constituents of Beilschmiedia cryptocaryoides. |
| AID1303894 | Antibacterial activity against multidrug resistant Acinetobacter baumannii 2208 (ATCC 19606) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID543427 | Antimicrobial activity against Escherichia coli XL-1 Blue harboring plasmid CL1920 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime. |
| AID371356 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs | 2009 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 19, Issue:3 | Synthesis and antimicrobial activities of halogenated bis(hydroxyphenyl)methanes. |
| AID529615 | Antibacterial activity against Beta-lactamase positive Haemophilus influenzae isolate after 20 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID436283 | Antibacterial activity against Staphylococcus aureus ATCC 65389 after 24 hrs by twofold dilution method | 2008 | Journal of natural products, Nov, Volume: 71, Issue:11 | Scalarane sesterterpenes from the sponge Smenospongia sp. |
| AID368421 | Antimicrobial activity against Escherichia coli KAM32 pSTV28 containing chloramphenicol-resistant vector by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID1159095 | Antimicrobial activity against Micrococcus luteus ATCC 9341 assessed as zone of inhibition at 10 mg for 24 hrs at 30 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID587959 | Activity of Escherichia coli beta-lactamase Toho-1 N104D mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID529830 | Antimicrobial activity against Acinetobacter baumannii assessed as susceptible isolates by microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | In vitro activity of tigecycline against multidrug-resistant Acinetobacter baumannii and selection of tigecycline-amikacin synergy. |
| AID460800 | Antibacterial activity against Acinetobacter baumannii UH8407 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID585864 | Antimicrobial activity against Pseudomonas aeruginosa isolate 12 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID69331 | Minimum inhibitory concentration of Ampicillin required for growth inhibition of Beta lactamase producing bacteria Clinically isolated Escherichia coli (TH-13) | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8 | Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives. |
| AID1577955 | Antimicrobial activity against Pseudomonas aeruginosa PA6 under iron-deficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID1769961 | Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC48706 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID546966 | Antibacterial activity against Aeromonas hydrophila by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1193888 | Antimicrobial activity against Klebsiella pneumoniae MTCC 3384 after 24 hrs by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Rapid 'one-pot' synthesis of a novel benzimidazole-5-carboxylate and its hydrazone derivatives as potential anti-inflammatory and antimicrobial agents. |
| AID558323 | Antibacterial activity against Campylobacter jejuni isolate P270 harboring blaOXA-61::cat gene by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID633458 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by two fold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial activity of brominated resorcinol dimers. |
| AID420229 | Antimicrobial activity against coagulase-negative Staphylococcus H.A.M. 338 isolate after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID1159104 | Antimicrobial activity against Bacillus thuringiensis assessed as zone of inhibition at 10 mg for 24 hrs at 30 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID1825298 | Antibacterial activity against Helicobacter pylori G27 assessed as bacterial growth inhibition | |||
| AID585858 | Antimicrobial activity against Pseudomonas aeruginosa isolate 9 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID677750 | Antibacterial activity against Salmonella typhimurium after 18 hrs | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17 | Two novel bioactive glucosinolates from Broccoli (Brassica oleracea L. var. italica) florets. |
| AID1585545 | Antibacterial activity against Klebsiella pneumoniae assessed as zone of inhibition at 1 mg/ml after 32 hrs by agar-well diffusion method | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Benzofuran derivatives and their anti-tubercular, anti-bacterial activities. |
| AID585017 | Antibacterial activity against Mycobacterium smegmatis MC2 155 ATCC | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Inhibition of bacterial multidrug resistance by celecoxib, a cyclooxygenase-2 inhibitor. |
| AID1114820 | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 18 to 24 hr by double microdilution method | 2013 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, Aug, Volume: 22, Issue:8 | |
| AID587968 | Ratio of Kcat to Km for Escherichia coli wild type beta-lactamase Toho-1 assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID1827138 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as inhibition of bacterial growth after 18 hrs by CLSI protocol based broth microdilution assay | 2022 | ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3 | Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA. |
| AID535457 | Antimicrobial activity against Lactobacillus sp. by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1759339 | Antibacterial activity against Escherichia coli MTCC 443 assessed as bacterial growth inhibition by microdilution method | 2021 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 41 | Design and synthesis, biological evaluation of bis-(1,2,3- and 1,2,4)-triazole derivatives as potential antimicrobial and antifungal agents. |
| AID572256 | Antibacterial activity against Fusobacterium varium by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID368419 | Antimicrobial activity against Escherichia coli KAM32 expressing deltaacrB ydhE hsd gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID405090 | Antimicrobial activity against integron carrying Enterobacteriaceae assessed as percent resistant isolates | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Enterobacteriaceae bloodstream infections: presence of integrons, risk factors, and outcome. |
| AID562222 | Antimicrobial activity against Desulfovibrio desulfuricans Essex 6 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID529743 | Antibacterial activity against Beta-lactamase positive Haemophilus influenzae isolate harboring fst1 mutant gene after 20 to 24 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID557958 | Antimicrobial activity in Eggerthella lenta by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID547179 | Antibacterial activity against Vibrio alginolyticus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1544801 | Antimicrobial activity against Pseudomonas aeruginosa assessed as zone of inhibition at 25 ug/disk after 24 hrs by disk diffusion method | 2019 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 29, Issue:13 | Synthesis and biological evaluation of 2-chloro-3-[(thiazol-2-yl)amino]-1,4-naphthoquinones. |
| AID564813 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID548485 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm, graRm mutant gene after 48 hrs by Etest in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID572047 | Antibacterial activity against Clostridium sporosphaeroides by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID557422 | Antimicrobial activity in Bacteroides vulgatus by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID535249 | Antimicrobial activity against Coprobacillus cateniformis by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID543819 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 assessed as eradication of pre-formed biofilm at 50 times MIC after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID1504825 | Antibacterial activity against beta-lactamase producing methicillin-resistant Staphylococcus aureus ATCC 11632 after 24 hrs by broth microdilution method | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12 | Sulfur-Containing Aristoloxazines and Other Constituents of the Roots of Aristolochia orbicularis. |
| AID613612 | Antibacterial activity against 10'8 CFU/mL Escherichia coli MTCC 443 by NCCLS M100-S12(M7) broth microdilution method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis and identification of β-aryloxyquinolines and their pyrano[3,2-c]chromene derivatives as a new class of antimicrobial and antituberculosis agents. |
| AID1364562 | Antimicrobial activity against Bacillus cereus incubated for 20 hrs by CLSI protocol based method | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | Identification of Pyridinium with Three Indole Moieties as an Antimicrobial Agent. |
| AID1908118 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC BAA-1720 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID456082 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID1365603 | Antibacterial activity against Bacillus subtilis MTCC 441 by broth microdilution method | 2017 | Bioorganic & medicinal chemistry, 11-01, Volume: 25, Issue:21 | Recently reported biological activities of pyrazole compounds. |
| AID533428 | Antimicrobial activity against Peptostreptococcus sp. assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID543423 | Antimicrobial activity against Escherichia coli XL-1 Blue transconjugant harboring beta-lactamase CTX-M-64 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime. |
| AID736477 | Antibacterial activity against Bacillus subtilis RCMB 010063 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID392754 | Antibacterial activity against Bacillus subtilis 6633 after 18 to 24 hrs by tube dilution method | 2009 | Bioorganic & medicinal chemistry, Feb-15, Volume: 17, Issue:4 | Synthesis and antimicrobial evaluation of some new substituted purine derivatives. |
| AID1204967 | Antimicrobial activity against Kocuria rhizophila NBRC 12708 after 24 hrs by twofold dilution method | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Additional sesterterpenes and a nortriterpene saponin from the sponge Clathria gombawuiensis. |
| AID1231416 | Antibacterial activity against Escherichia coli ATCC 35218 assessed as growth inhibition at 20 ug after 24 hrs by disc agar diffusion method in presence of sulbactam | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and biological evaluation of caracasine acid derivatives. |
| AID1759336 | Antibacterial activity against Staphylococcus aureus MTCC 96 assessed as bacterial growth inhibition by microdilution method | 2021 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 41 | Design and synthesis, biological evaluation of bis-(1,2,3- and 1,2,4)-triazole derivatives as potential antimicrobial and antifungal agents. |
| AID1079942 | Steatosis, proven histopathologically. Value is number of references indexed. [column 'STEAT' in source] | |||
| AID1114116 | Antibacterial activity against Bacillus subtilis ATCC 6633 assessed as growth inhibition by broth microdilution method | 2013 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, May, Volume: 22, Issue:5 | Microbiologically active Mannich bases derived from 1,2,4-triazoles. The effect of C-5 substituent on antibacterial activity. |
| AID530254 | Antimicrobial activity against ygfA deficient Escherichia coli K-12 BW-25113 assessed as decrease in persistence at 100 ug/ml after 3 hrs by time kill analysis | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. |
| AID1496309 | Antibacterial activity against vancomycin-resistant Enterococcus faecalis 342B after 24 hrs | 2018 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 28, Issue:12 | In vitro activity of salicylamide derivatives against vancomycin-resistant enterococci. |
| AID368422 | Antimicrobial activity against Escherichia coli KAM32 pSTVqepA containing qepA gene ligated to pSTV28 plasmid by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID587196 | Antimicrobial activity against Bacillus subtilis after 18 hrs by broth microdilution method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Comazaphilones A-F, azaphilone derivatives from the marine sediment-derived fungus Penicillium commune QSD-17. |
| AID278260 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS14 with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID198326 | In vitro testing for minimum inhibitory concentration against Salmonella Typhimurium LT2 168 | 1987 | Journal of medicinal chemistry, Dec, Volume: 30, Issue:12 | Design and synthesis of peptide derivatives of a 3-deoxy-D-manno-2-octulosonic acid (KDO) analogue as novel antibacterial agents acting upon lipopolysaccharide biosynthesis. |
| AID587962 | Activity of Escherichia coli beta-lactamase Toho-1 N104A mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID1176780 | Antimicrobial activity against Candida glabrata ATCC 9984 after 24 hrs by broth microdilution method | 2015 | Journal of natural products, Jan-23, Volume: 78, Issue:1 | Structure and antimicrobial activity of phloroglucinol derivatives from Achyrocline satureioides. |
| AID1868097 | Antibacterial activity against Staphylococcus aureus ATCC 9144 assessed as inhibition of visible bacterial growth incubated for 18 hrs by CLSI protocol based assay | 2022 | Journal of natural products, 05-27, Volume: 85, Issue:5 | Enceleamycins A-C, Furo-Naphthoquinones from |
| AID519651 | Antimicrobial activity against Escherichia coli Irk1224 type 2 mutant harboring beta-lactamase CTX-M-3 Ser167 mutant gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID723725 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID535245 | Antimicrobial activity against Catenibacterium mitsuokai by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID318707 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID442411 | Antimicrobial activity against Escherichia coli at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID555450 | Antibacterial activity against Escherichia coli DH5alpha by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID555244 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 56 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID601600 | Antibacterial activity against Gordonia sp. isolate Fs48 at 10 ug/disk after 24 hrs by disc diffusion assay | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Synthesis of 2-aziridinyl phosphonates by modified Gabriel-Cromwell reaction and their antibacterial activities. |
| AID1546172 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as zone of inhibition at 100 ug/ml after 24 hrs by disc diffusion method | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID555267 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 128 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID587965 | Activity of Escherichia coli beta-lactamase Toho-1 C69A mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID1546161 | Antifungal activity against Aspergillus niger | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID547992 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237Y mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID85795 | The compound was tested in vivo for antibacterial activity against AmpR beta(+) Haemophilus influenza 351RD7 in mice after oral administration | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21 | Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens. |
| AID555476 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 243 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1156859 | Antimicrobial activity against Escherichia coli ATCC 9637 after 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents. |
| AID1436940 | Antibacterial activity against Pseudomonas fluorescens ATCC 13525 after 8 hrs | 2017 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 27, Issue:4 | Quinolidene based monocarbonyl curcumin analogues as promising antimycobacterial agents: Synthesis and molecular docking study. |
| AID324303 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoR mutant assessed as cell count in stationary phase at 100 ug/ml after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID530511 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype III isolate 7507-03 expressing pbp2x Q557E mutant and multilocus sequence type ST19 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID572026 | Antibacterial activity against Clostridium difficile by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID528606 | Activity of Escherichia coli 2138 beta-lactamase KPC-2 by spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France. |
| AID373678 | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 24 hrs by broth microdilution method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID471910 | Antibacterial activity against Staphylococcus aureus MTCC 1144 after 12 to 16 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | A facile one-pot green synthesis and antibacterial activity of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes. |
| AID1546104 | Antimicrobial activity against Bacillus cereus | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID285512 | Antibacterial activity against Escherichia coli after 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens. |
| AID365668 | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 24 hrs by twofold serial dilution method | 2008 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 18, Issue:16 | Substituted 3-((Z)-2-(4-nitrophenyl)-2-(1H-tetrazol-5-yl) vinyl)-4H-chromen-4-ones as novel anti-MRSA agents: synthesis, SAR, and in-vitro assessment. |
| AID546925 | Antibacterial activity against Salmonella enterica serovar Typhimurium assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID535489 | Antimicrobial activity against Ruminococcus productus by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID289315 | Antibacterial activity against Escherichia coli ATCC 23556 after 24 hrs | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18 | Synthesis and antimicrobial activity of some new thiazolyl thiazolidine-2,4-dione derivatives. |
| AID362534 | Antibacterial activity against Bacillus subtilis assessed as zone of inhibition at 0.25 mg/mL by agar well diffusion method | 2008 | Journal of natural products, Aug, Volume: 71, Issue:8 | Bioactive 5alpha-pregnane-type steroidal alkaloids from Sarcococca hookeriana. |
| AID648405 | Antibacterial activity against Staphylococcus aureus ATTC 25923 at MIC after 3 to 4 days by disc diffusion method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Facile synthesis, characterization and pharmacological activities of 3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 5,6-dihydro-3,6-disubstituted-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles. |
| AID1762806 | Antibacterial activity against Escherichia coli 08 assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | 2021 | Bioorganic & medicinal chemistry, 05-15, Volume: 38 | Dipyridyl-substituted thiosemicarbazone as a potent broad-spectrum inhibitor of metallo-β-lactamases. |
| AID1471036 | Growth inhibition of Pseudomonas fluorescens NCIM 2059 at 30 ug/ml measured after 8 hrs relative to control | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID362539 | Antibacterial activity against Micrococcus luteus by agar well diffusion method | 2008 | Journal of natural products, Aug, Volume: 71, Issue:8 | Bioactive 5alpha-pregnane-type steroidal alkaloids from Sarcococca hookeriana. |
| AID534935 | Antimicrobial activity against Desulfovibrio piger by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1657466 | Antibacterial activity against Micrococcus luteus SCSIO ML01 by CLSI based susceptibility test method | 2020 | Journal of natural products, 04-24, Volume: 83, Issue:4 | Proximicins F and G and Diproximicin A: Aminofurans from the Marine-Derived |
| AID278557 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium thermophilum ATCC 25866 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID565003 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus hominis after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID547996 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237C mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID279562 | Antimicrobial activity against Haemophilus influenzae BLPAR strains | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Diversity of ampicillin resistance genes and antimicrobial susceptibility patterns in Haemophilus influenzae strains isolated in Korea. |
| AID324174 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid PhoU at 6 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID565751 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecalis clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID456084 | Antibacterial activity against Proteus mirabilis after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID535433 | Antimicrobial activity against Eubacterium cylindroides by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID561446 | Antibacterial activity against Escherichia coli DH10B harboring plasmid BCSK carrying beta-lactamase CMY-2 gene by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Reduced susceptibility to cefepime among Escherichia coli clinical isolates producing novel variants of CMY-2 beta-lactamase. |
| AID670273 | Antibacterial activity against Proteus vulgaris ATCC 3851 after 24 hrs | 2012 | Bioorganic & medicinal chemistry, Jul-01, Volume: 20, Issue:13 | Beta-carboline alkaloids derived from the ascidian Synoicum sp. |
| AID85794 | The compound was tested for minimal inhibitory concentration against Haemophilus ducreyi | 2002 | Bioorganic & medicinal chemistry letters, Sep-02, Volume: 12, Issue:17 | The activity of p-methoxybenzylisothiocyanate against Neisseria gonorrhoeae, Haemophilus ducreyi, and other microorganisms. |
| AID421839 | Antibacterial activity against Salmonella Typhimurium ATCC 14028 | 2009 | Journal of natural products, Feb-27, Volume: 72, Issue:2 | Glionitrin A, an antibiotic-antitumor metabolite derived from competitive interaction between abandoned mine microbes. |
| AID585841 | Antimicrobial activity against Pseudomonas aeruginosa isolate 1 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID555264 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 109 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID278554 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium longum R0175 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID590507 | Antibacterial activity against Escherichia coli ATCC 27853 after 24 hrs | 2011 | European journal of medicinal chemistry, Apr, Volume: 46, Issue:4 | Synthesis, biopharmaceutical characterization, antimicrobial and antioxidant activities of 1-(4'-O-β-D-glucopyranosyloxy-2'-hydroxyphenyl)-3-aryl-propane-1,3-diones. |
| AID1423473 | Inhibition of refolded MDH (unknown origin) preincubated with Escherichia coli GroEL/GroES for 45 mins in absence of compound followed by compound addition and measured for 20 to 35 mins by spectrometric analysis | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID1818975 | Antibacterial activity against Staphylococcus aureus ATCC 6538 assessed as bacterial clearance incubated for 6 to 24 hrs by microbroth dilution method | 2022 | Journal of medicinal chemistry, 01-13, Volume: 65, Issue:1 | Discovery of |
| AID534719 | Antimicrobial activity against Parabacteroides merdae by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID543804 | Bactericidal activity against Staphylococcus aureus ATCC 29213 assessed as eradication of pre-formed biofilm at 1 to 10 times MIC after 24 hrs by serial dilution | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID775556 | Antimicrobial activity against Clostridium perfringens CNCTC 5770 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21 | New derivatives of salicylamides: Preparation and antimicrobial activity against various bacterial species. |
| AID401599 | Antibacterial activity against Staphylococcus aureus ATCC 29213 at 10 ug/disk after 48 hrs by standard paper sensitivity disk-agar plate method | 2004 | Journal of natural products, May, Volume: 67, Issue:5 | 5-methylcoumaranones from Mutisia friesiana and their bioactivity. |
| AID572246 | Antibacterial activity against Streptococcus intermedius by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID585642 | Antimicrobial activity against ampD, ampDh1, ampDh2 deficient Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID736476 | Antibacterial activity against Enterococcus faecalis RCMB 010068 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID304968 | Antibacterial activity against Klebsiella pneumoniae by broth micro-dilution technique | 2007 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1 | New antifungal flavonoid glycoside from Vitex negundo. |
| AID533874 | Antibacterial activity against penicillin-nonsusceptible Streptococcus pneumoniae isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro activity of ceftaroline against Streptococcus pneumoniae isolates exhibiting resistance to penicillin, amoxicillin, and cefotaxime. |
| AID1159099 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 35032 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID203328 | Minimum inhibitory concentration of Ampicillin required for growth inhibition of Beta lactamase producing bacteria Serratia marcescens | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8 | Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives. |
| AID666961 | Antibacterial activity against Escherichia coli MTCC 443 by broth microdilution method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | New N-arylamino biquinoline derivatives: synthesis, antimicrobial, antituberculosis, and antimalarial evaluation. |
| AID324286 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoR mutant assessed as cell count in log phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID530512 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype III isolate 8607-03 expressing pbp2x Q557E mutant and multilocus sequence type ST19 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID1546116 | Antifungal activity against Candida tropicalis | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID471906 | Antibacterial activity against Pseudomonas putida MTCC 1072 after 12 to 16 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | A facile one-pot green synthesis and antibacterial activity of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes. |
| AID693580 | Antibacterial activity against Staphylococcus aureus MTCC 3160 after 24 hrs by tube dilution method | 2012 | European journal of medicinal chemistry, Dec, Volume: 58 | Synthesis pharmacological evaluation and docking studies of pyrimidine derivatives. |
| AID777334 | Antibacterial activity against Klebsiella pneumoniae ATCC 27736 assessed as growth inhibition after 24 hrs by microbroth dilution method | 2013 | ACS medicinal chemistry letters, Oct-10, Volume: 4, Issue:10 | Identification of 1-[4-Benzyloxyphenyl)-but-3-enyl]-1H-azoles as New Class of Antitubercular and Antimicrobial Agents. |
| AID429268 | Antibacterial activity against Klebsiella pneumoniae at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents. |
| AID399621 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 at 0.1 mg/disk by disk diffusion assay | |||
| AID547787 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237L mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID549330 | Antimicrobial activity against Escherichia coli isolate 16 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID278263 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS14 tolC::Kan with GyrA D87G mutant | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID405084 | Activity of Citrobacter freundii PER2 beta lactamase | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Biochemical characterization of PER-2 and genetic environment of blaPER-2. |
| AID536088 | Antimicrobial activity against Bacillus subtilis IFO 3007 after 24 hrs | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID736475 | Antibacterial activity against Neisseria gonorrhoeae RCMB 010076 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID299671 | Antibacterial activity against Staphylococcus aureus by disk diffusion method | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Synthesis and evaluation of amphiphilic cationic quinine-derived for antibacterial activity against methicillin-resistant Staphylococcus aureus. |
| AID369440 | Antimicrobial activity against vancomycin-resistant Enterococcus faecalis after 20 to 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe. |
| AID524966 | Antibacterial activity against vancomycin-susceptible Enterococcus faecalis clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Comparative surveillance study of telavancin activity against recently collected gram-positive clinical isolates from across the United States. |
| AID322316 | Antibacterial activity against CTX-M group 9 enzyme producing Escherichia coli isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal. |
| AID1677486 | Antimicrobial activity against Staphylococcus aureus ATCC 6538p | 2020 | Journal of natural products, 10-23, Volume: 83, Issue:10 | Sortase A-Inhibitory Coumarins from the Folk Medicinal Plant |
| AID1411623 | Bactericidal activity against Staphylococcus aureus ATCC 6538 incubated for 24 hrs followed by serial sub-cultivation and measured after 24 hrs by microdilution method | |||
| AID322317 | Antibacterial activity against CTX-M group 9 enzyme producing Escherichia coli isolates assessed as percent resistant isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal. |
| AID573340 | Antibacterial activity against ceftazidime-susceptible Citrobacter freundii by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID530051 | Antimicrobial activity against Staphylococcus aureus 286607-R1 harboring wild type gyrB by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. |
| AID585193 | Antimicrobial activity against Escherichia coli DH5[alpha] transformed with pAC-ges1 plasmid encoding Beta-lactamase GES-1 E104, G170 mutant by Etest method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases. |
| AID1159102 | Antimicrobial activity against Bacillus cereus ATCC 11778 assessed as zone of inhibition at 10 mg for 24 hrs at 30 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID546941 | Antibacterial activity against Salmonella enterica serovar Newport assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID278248 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS1 with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1423481 | Cytotoxicity against human THLE3 cells assessed as reduction in cell viability after 48 hrs by Alamar Blue reporter assay | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID278528 | Antimicrobial activity against Bifidobacterium longum ATCC 15708 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1907030 | Antibacterial activity against Salmonella enterica 87 strain assessed as inhibition of bacterial growth incubated for 8 hrs by CLSI protocol based microdilution assay | 2022 | Journal of medicinal chemistry, 04-14, Volume: 65, Issue:7 | Design, Synthesis, and Proof-of-Concept of Triple-Site Inhibitors against Aminoacyl-tRNA Synthetases. |
| AID278269 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS38 gyrA+ with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID535475 | Antimicrobial activity against Peptostreptococcus anaerobius by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID572234 | Antibacterial activity against Ruminococcus luti by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID529885 | Antibacterial activity against Staphylococcus aureus RN4220 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. |
| AID334237 | Antimicrobial activity against Trichophyton tonsurans EQ 4329 after 10 days by microdilution technique | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4 | Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline. |
| AID585452 | Antimicrobial activity against ampD, ampDh2, ampDh3 and ampG deficient Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID520994 | Antimicrobial activity against Francisella tularensis SCHU-S4 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Novel antimicrobial peptides that exhibit activity against select agents and other drug resistant bacteria. |
| AID529161 | FIC index, ratio of MIC for Pseudomonas aeruginosa 100609 in presence of 250 ug/ml polyethylenimine to MIC for Pseudomonas aeruginosa 100609 | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa. |
| AID547187 | Antibacterial activity against Vibrio vulnificus assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID255518 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 1.0 uM/ml in dimethylformamide, + = resistant | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID422493 | Antimicrobial activity against Carnobacterium divergens BM4490 expressing beta-lactamase CAD1 at 3 McFarland inoculum size by E-test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens. |
| AID572260 | Antibacterial activity against Prevotella denticola by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID655625 | Antibacterial activity against Pseudomonas aeruginosa ATCC 15499 at 80 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID727796 | Antimicrobial activity against Escherichia coli DH10B expressing Beta-lactamase SHV-1 K234R protein mutant by CLSI agar dilution method | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3 | Design and exploration of novel boronic acid inhibitors reveals important interactions with a clavulanic acid-resistant sulfhydryl-variable (SHV) β-lactamase. |
| AID532678 | Antimicrobial activity against ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates assessed as resistant isolates by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. |
| AID674907 | Antibacterial activity against Escherichia coli MTCC 443 | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17 | Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives. |
| AID529196 | Antibacterial activity against ESBL-producing Escherichia coli isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Comparison of antimicrobial resistance profiles among extended-spectrum-beta-lactamase-producing and acquired AmpC beta-lactamase-producing Escherichia coli isolates from Canadian intensive care units. |
| AID1399262 | Antimicrobial activity against Escherichia coli BW25113 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID535356 | Antimicrobial activity against Streptococcus pyogenes clinical isolates by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Antimicrobial resistance among respiratory pathogens in Spain: latest data and changes over 11 years (1996-1997 to 2006-2007). |
| AID537665 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs by agar-well diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Cyclization of some carbothioamide derivatives containing antipyrine and triazole moieties and investigation of their antimicrobial activities. |
| AID521967 | Antibacterial activity against Campylobacter coli assessed as resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID429263 | Antibacterial activity against Staphylococcus aureus at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents. |
| AID735975 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs by microdilution susceptibility test | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Synthesis and antimicrobial activity of some new benzo and naphthonitrile derivatives. |
| AID1695859 | Antibacterial activity against Staphylococcus aureus ATCC 29737 incubated for 24 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID279560 | Antimicrobial activity against Haemophilus influenzae strains that are normal flora | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Diversity of ampicillin resistance genes and antimicrobial susceptibility patterns in Haemophilus influenzae strains isolated in Korea. |
| AID534971 | Antimicrobial activity against Clostridium clostridioforme by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1423476 | Antibacterial activity against Klebsiella pneumoniae ATCC 13883 after 6 to 8 hrs by bacterial proliferation assay | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID600671 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID456083 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID555245 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 56 by Etest method in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID294966 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID548021 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237E mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID731206 | Antibacterial activity against Bacillus subtilis MTCC 441 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles. |
| AID372553 | Antibacterial activity against genetically beta-lactamase-negative ampicillin-susceptible Haemophilus influenzae type b without amino acid substitutions in ftsI gene and bla gene assessed as susceptibility rate by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID1337846 | Antifungal activity against Aspergillus niger NCIM 1196 by standard agar method | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Quinolidene-rhodanine conjugates: Facile synthesis and biological evaluation. |
| AID1228011 | Antimicrobial activity against Bacillus subtilis CGMCC 1.1470 assessed as complete prevention of visible growth after incubation at 37 degC for 18 to 20 hrs | 2015 | Journal of natural products, Apr-24, Volume: 78, Issue:4 | Antibacterial Biphenanthrenes from the Fibrous Roots of Bletilla striata. |
| AID1870160 | Antibacterial activity against wild type Staphylococcus aureus 77/CF assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID523266 | Activity at Escherichia coli isolate 7181 beta-lactamase OXA-7 | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Kinetic parameters of efflux of penicillins by the multidrug efflux transporter AcrAB-TolC of Escherichia coli. |
| AID285194 | Antimicrobial activity against Escherichia coli M064 mutant with AG100 lon1::IS186 acrR::IS genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID85790 | In vitro inhibitory activity against Haemophilus AmpR (37) | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID373676 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by broth microdilution method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID387670 | Antibacterial activity against Salmonella typhi AE 14612 after 48 hrs by disc diffusion method | 2008 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 18, Issue:19 | Design and synthesis of 3-pyrazolyl-thiophene, thieno[2,3-d]pyrimidines as new bioactive and pharmacological activities. |
| AID529606 | Ratio of Kcat to Km for Escherichia coli Beta-Lactamase TEM-1 | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID1870150 | Antibacterial activity against wild type Staphylococcus aureus 4740/B assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID531314 | Ratio of Kcat to Km for Pseudomonas aeruginosa beta-lactamase VIM-7 by spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family. |
| AID585198 | Antimicrobial activity against Escherichia coli DH5[alpha] by Etest method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases. |
| AID1668055 | Inhibition of DHPS in Escherichia coli assessed as antibacterial activity by measuring inhibition zone at 5 mg/mL incubated for 24 hrs by disk diffusion method | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9 | New acrylamide-sulfisoxazole conjugates as dihydropteroate synthase inhibitors. |
| AID1853151 | Antibacterial activity against Macrolide resistant Streptococcus pyogenes clinical isolate B0545 assessed as inhibition of bacterial growth incubated for 20 to 22 hrs by broth microdilution method | 2022 | RSC medicinal chemistry, Dec-14, Volume: 13, Issue:12 | Novel tetrahydropyrimidinyl-substituted benzimidazoles and benzothiazoles: synthesis, antibacterial activity, DNA interactions and ADME profiling. |
| AID436284 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by twofold dilution method | 2008 | Journal of natural products, Nov, Volume: 71, Issue:11 | Scalarane sesterterpenes from the sponge Smenospongia sp. |
| AID543810 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 assessed as eradication of pre-formed biofilm at 50 times MIC after 24 hrs by serial dilution | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID1596678 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID573373 | Antibacterial activity against multidrug-resistant Acinetobacter by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID582764 | Antimicrobial activity against eaeA negative verocytotoxin-producing non-O157 Escherichia coli isolates obtained from human assessed as percentage of resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID287241 | Antimicrobial activity against Escherichia coli IFO 3301 after 24 hrs | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles. |
| AID532980 | Antibacterial activity against Escherichia coli DH5alpha in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID1491343 | Antifungal activity against Aspergillus fumigatus 293 after 48 hrs by two-fold serial dilution method | 2017 | European journal of medicinal chemistry, Sep-08, Volume: 137 | Synthesis, antimicrobial, antiquorum-sensing and antitumor activities of new benzimidazole analogs. |
| AID529575 | Activity of Erwinia carotovora subsp. atroseptica DSM 30184 beta-lactamase CAR-1 | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora. |
| AID568675 | Antimicrobial activity against Streptococcus pyogenes assessed as growth inhibition at 10 ug/ml by agar dilution method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and structure-activity relationship of 2-thiopyrimidine-4-one analogs as antimicrobial and anticancer agents. |
| AID405324 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae group IIc isolates with acrR aminoacid substitution mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID600677 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID1264891 | Antimicrobial activity against Staphylococcus aureus ATCC 12600 for 17 to 48 hrs by MTT assay | 2015 | Journal of natural products, Nov-25, Volume: 78, Issue:11 | Identification of Elaiophylin Skeletal Variants from the Indonesian Streptomyces sp. ICBB 9297. |
| AID478781 | Antibacterial activity against Micrococcus luteus ATCC 9345 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5 | Synthesis, spectroscopic and biological studies on the new symmetric Schiff base derived from 2,6-diformyl-4-methylphenol with N-aminopyrimidine. |
| AID573361 | Antibacterial activity against ceftazidime-nonsusceptible Klebsiella pneumoniae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID294416 | Antifungal activity against Aspergillus niger at 25 ug/mL by agar diffusion technique | 2007 | European journal of medicinal chemistry, Jul, Volume: 42, Issue:7 | Synthesis and antimicrobial evaluation of some new thiazole, thiazolidinone and thiazoline derivatives starting from 1-chloro-3,4-dihydronaphthalene-2-carboxaldehyde. |
| AID360049 | Antimicrobial activity against Enterococcus faecium D344S by agar dilution method after 48 hrs | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID573341 | Antibacterial activity against ceftazidime-susceptible Citrobacter freundii assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID655629 | Antibacterial activity against Salmonella typhimurium ATCC 23564 at 80 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID519653 | Antimicrobial activity against Escherichia coli GM2995 harboring plasmid pCC1 carrying beta-lactamase CTX-M-3 gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID1272237 | Antibacterial activity against Staphylococcus aureus by broth micro-dilution method | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3 | Efficiently functionalized oxacalix[4]arenes: Synthesis, characterization and exploration of their biological profile as novel HDAC inhibitors. |
| AID504047 | Antimicrobial activity against Escherichia coli MTCC 443 by broth microdilution technique | 2010 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 20, Issue:18 | Synthesis and antimicrobial activity of novel fluorine containing 4-(substituted-2-hydroxybenzoyl)-1H-pyrazoles and pyrazolyl benzo[d]oxazoles. |
| AID745303 | Antibacterial activity against Vibrio cholerae MTCC 3906 assessed as growth inhibition after overnight incubation by NCCLS broth microdilution method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Synthesis and identification of β-aryloxyquinoline based diversely fluorine substituted N-aryl quinolone derivatives as a new class of antimicrobial, antituberculosis and antioxidant agents. |
| AID544586 | Antimicrobial activity against Escherichia coli DH5[alpha] isolate GC 8128 expressing bla SHV-105 gene by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Pyrosequencing using the single-nucleotide polymorphism protocol for rapid determination of TEM- and SHV-type extended-spectrum beta-lactamases in clinical isolates and identification of the novel beta-lactamase genes blaSHV-48, blaSHV-105, and blaTEM-155 |
| AID655620 | Antibacterial activity against Burkholderia pseudomallei NTCC 10274 at 160 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID572224 | Antibacterial activity against Colinsella aerofaciens by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1056541 | Antibacterial activity against Escherichia coli ATCC 25922 by broth microdilution method | 2013 | Journal of natural products, Dec-27, Volume: 76, Issue:12 | Cytotoxic and antibacterial marfuraquinocins from the deep South China Sea-derived Streptomyces niveus SCSIO 3406. |
| AID325485 | Antimicrobial activity against beta-lactamase producing Enterococcus faecalis TX0630 isolate by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Time-kill and synergism studies of ceftobiprole against Enterococcus faecalis, including beta-lactamase-producing and vancomycin-resistant isolates. |
| AID693579 | Antibacterial activity against Bacillus subtilis MTCC 441 after 24 hrs by tube dilution method | 2012 | European journal of medicinal chemistry, Dec, Volume: 58 | Synthesis pharmacological evaluation and docking studies of pyrimidine derivatives. |
| AID1762804 | Antibacterial activity against against Escherichia coli 04 assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | 2021 | Bioorganic & medicinal chemistry, 05-15, Volume: 38 | Dipyridyl-substituted thiosemicarbazone as a potent broad-spectrum inhibitor of metallo-β-lactamases. |
| AID276383 | Antibacterial activity against Streptococcus faecalis by broth microdilution technique | 2006 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 16, Issue:22 | Naphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: synthesis and biological evaluation as potential antibacterial and antifungal agents. |
| AID681347 | TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cells | 1997 | The American journal of physiology, 11, Volume: 273, Issue:5 | Recognition of beta-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells. |
| AID557744 | Antimicrobial activity in Anaerococcus tetradius by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1286499 | Bactericidal activity against methicillin-sensitive Staphylococcus aureus ATCC 49775 after 24 and 48 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID405318 | Antibacterial activity against Haemophilus influenzae group III-like isolates with ftsI gene mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID679007 | TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 25000 uM) in PEPT1-expressing CHO cells | 1996 | Pharmaceutical research, Nov, Volume: 13, Issue:11 | Human dipeptide transporter, hPEPT1, stably transfected into Chinese hamster ovary cells. |
| AID325443 | Antibacterial activity against Escherichia coli K10 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID448252 | Antibacterial activity against Escherichia coli at 2 mg/ml after 24 hrs by agar diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new heterocycles incorporating phthalazine. |
| AID662074 | Antibacterial activity against Bacillus megaterium after 20 hrs by liquid growth inhibition assay | 2012 | Journal of medicinal chemistry, Mar-08, Volume: 55, Issue:5 | From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity. |
| AID565663 | Antimicrobial activity against beta-lactamase negative ampicillin-resistant Haemophilus influenzae assessed as susceptible isolates by broth microdilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID587967 | Activity of Escherichia coli beta-lactamase Toho-1 G232A mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID1139547 | Antibacterial activity against Escherichia coli DH5alpha expressing beta-lactamase KPC-3 by CLSI broth microdilution method | 2014 | Journal of medicinal chemistry, May-08, Volume: 57, Issue:9 | Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. |
| AID1870140 | Antibacterial activity against wild type Staphylococcus aureus 4557/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID444055 | Fraction absorbed in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID1266799 | Antibacterial activity against Proteus hauseri NBRC 3851 after 24 hrs at 37 degC by broth dilution method | 2015 | Journal of natural products, Nov-25, Volume: 78, Issue:11 | Meroterpenoids from a Tropical Dysidea sp. Sponge. |
| AID1648085 | Antibacterial activity against Enterococcus faecium ATCC 19434 assessed as reduction in microbial growth after 24 hrs by two-fold serial dilution method | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Absolute Configuration and Antibiotic Activity of Piceamycin. |
| AID1854170 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 | 2022 | European journal of medicinal chemistry, Aug-05, Volume: 238 | Cascade synthetic strategies opening access to medicinal-relevant aliphatic 3- and 4-membered N-heterocyclic scaffolds. |
| AID510168 | Antimicrobial activity against extended spectrum beta lactamase expressing Klebsiella pneumoniae by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID529621 | Antibacterial activity against Beta-lactamase negative Haemophilus influenzae isolate harboring fst1 mutant gene after 20 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID572229 | Antibacterial activity against Propionibacterium propionicus by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1402053 | Antibacterial activity against ESBL positive Klebsiella pneumoniae ATCC 700603 after 18 to 20 hrs by spectrophotometry based microdilution method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid. |
| AID585444 | Antimicrobial activity against ampG deficient Pseudomonas aeruginosa PAO1 harboring pUCP24 conferring resistance to gentamycin after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID546968 | Antibacterial activity against Aeromonas hydrophila assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1382079 | Antibacterial activity against Escherichia coli ATCC 25922 after 18 to 24 hrs by double microdilution method | 2018 | European journal of medicinal chemistry, Feb-25, Volume: 146 | Ciprofloxacin derivatives and their antibacterial activities. |
| AID653696 | Displacement of angiopoietin 1 from human recombinant Tie2 at 50 to 100 uM | 2012 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 22, Issue:7 | Discovery of loperamide as an antagonist of angiopoietin1 and angiopoietin2 by virtual screening. |
| AID520718 | Antibacterial activity against Acinetobacter baumannii CIP7010 harboring pOXA-97 by disk diffusion method in presence of 4 ug/ml clavulanic acid | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID601598 | Antibacterial activity against Bacillus subtilis assessed as diameter of zone of inhibition at 10 ug/disk after 24 hrs by disc diffusion assay | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Synthesis of 2-aziridinyl phosphonates by modified Gabriel-Cromwell reaction and their antibacterial activities. |
| AID770914 | Antibacterial activity against Micrococcus luteus IFO 3232 assessed as growth inhibition at 100 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID1617683 | Antibacterial activity against Bacillus thuringiensis BT01 by CLSI based two-fold serial dilution method | |||
| AID520995 | Antimicrobial activity against Burkholderia mallei ATCC 23444 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Novel antimicrobial peptides that exhibit activity against select agents and other drug resistant bacteria. |
| AID577190 | Increase in Stx2 gene expression in Escherichia coli O157:H7 185 cocultured with Stx-phage susceptible Escherichia coli isolate CMUC-170 at 0.015 ug/ml by luciferase assay relative to untreated control | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID1594839 | Antibacterial activity against Listeria monocytogenes NCTC 7973 by microdilution method | 2019 | Journal of natural products, 06-28, Volume: 82, Issue:6 | Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. |
| AID545454 | Antimicrobial activity against extended-spectrum beta-lactamase-positive Proteus mirabilis assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID1314115 | Antibacterial activity against Escherichia coli K-12 in M9 minimal media by turbidometric method | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16 | Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents. |
| AID670274 | Antibacterial activity against Escherichia coli ATCC 35270 after 24 hrs | 2012 | Bioorganic & medicinal chemistry, Jul-01, Volume: 20, Issue:13 | Beta-carboline alkaloids derived from the ascidian Synoicum sp. |
| AID1908121 | Antibacterial activity against Bacillus subtilis CMCC (B) 63501 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID555671 | Antimicrobial activity against Escherichia coli DH5[alpha] harboring recombinant plasmid carrying CTX-M-53 gene by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg. |
| AID558801 | Antimicrobial activity against extended spectrum beta-lactamase-expressing Klebsiella oxytoca assessed as percent susceptible isolates by CLSI method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007. |
| AID548480 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm, graRm mutant gene after 24 hrs by Etest in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID1055942 | Antibacterial activity against Enterococcus faecalis ATCC 29212 at 10 ug/ml after 16 hrs | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID595438 | Antibacterial activity against Salmonella typhimurium ATCC 14028 after 24 hrs by by twofold serial dilution method | 2011 | Journal of natural products, Apr-25, Volume: 74, Issue:4 | Scalarane sesterterpenes from the sponge Hyatella sp. |
| AID1185237 | Antimicrobial activity against Bacillis subtilis RCMB 010067 assessed as absence of turbidity after 24 hrs | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety. |
| AID745301 | Antifungal activity against Candida albicans MTCC 227 assessed as growth inhibition after overnight incubation by NCCLS broth microdilution method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Synthesis and identification of β-aryloxyquinoline based diversely fluorine substituted N-aryl quinolone derivatives as a new class of antimicrobial, antituberculosis and antioxidant agents. |
| AID562935 | Upregulation of slpA gene expression in Clostridium difficile 6269 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID600683 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID671478 | Antibacterial activity against Staphylococcus lugdunensis isolate NTUH after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Aug-01, Volume: 20, Issue:15 | Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. |
| AID1079935 | Cytolytic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is > 5 (see ACUTE). Value is number of references indexed. [column 'CYTOL' in source] | |||
| AID1287514 | Antibacterial activity against Pseudomonas fluorescens NCIM 2036 after 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 26, Issue:7 | Synthesis, biological evaluation and molecular docking study of some novel indole and pyridine based 1,3,4-oxadiazole derivatives as potential antitubercular agents. |
| AID562522 | Antimicrobial activity against vancomycin-, gentamicin-resistant Enterococcus faecium TX1330RF-B2 conjugant expressing hylEfm gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Cotransfer of antibiotic resistance genes and a hylEfm-containing virulence plasmid in Enterococcus faecium. |
| AID1706154 | Antibacterial activity against Salmonella enterica 87 assessed as reduction in bacterial growth incubated for 18 hrs by CLSI based broth microdilution assay | |||
| AID555208 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 69 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID255527 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 8.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID269646 | Antifungal activity against Fusarium oxysporum f.sp.cubense | 2006 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 16, Issue:16 | Lactones from a brown alga endophytic fungus (No. ZZF36) from the South China Sea and their antimicrobial activities. |
| AID557209 | Antibacterial activity against Beta-lactamase-negative Neisseria meningitidis assessed as percent susceptible isolates by Etest method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antibiotic susceptibility and characteristics of Neisseria meningitidis isolates from the African meningitis belt, 2000 to 2006: phenotypic and genotypic perspectives. |
| AID561935 | Antibacterial activity against blaOXA-24-positive Acinetobacter baumannii isolate RUH134 harboring plasmid ABVA01 by CLSI broth microdilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Characterization of pABVA01, a plasmid encoding the OXA-24 carbapenemase from Italian isolates of Acinetobacter baumannii. |
| AID1870138 | Antibacterial activity against wild type methicillin resistant Staphylococcus aureus 4968/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID735978 | Antimicrobial activity against Bacillus thuringiensis after 24 hrs by by microdilution susceptibility test | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Synthesis and antimicrobial activity of some new benzo and naphthonitrile derivatives. |
| AID535233 | Antimicrobial activity against Bifidobacterium breve by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1261214 | Bacteriostatic activity against Staphylococcus aureus Mu50 after 24 hrs | 2015 | Bioorganic & medicinal chemistry, Nov-01, Volume: 23, Issue:21 | Evaluation of small molecule SecA inhibitors against methicillin-resistant Staphylococcus aureus. |
| AID548042 | Antimicrobial activity against Escherichia coli DH10B harboring plasmid pBK SK(+) by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID1225288 | Antibacterial activity against Bacillus subtilis ATCC 6633 incubated for 12 hrs at 37 degC | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Pentacyclic antibiotics from a tidal mud flat-derived actinomycete. |
| AID532984 | Antibacterial activity against Escherichia coli MG1655 in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID1290439 | Antibacterial activity against Streptococcus pneumoniae MTCC 1936 after 24 to 48 hrs by broth microdilution method | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities. |
| AID1157880 | Antimicrobial activity against Staphylococcus aureus ATCC 6538p after 24 hrs by two-fold broth dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Suvanine sesterterpenes and deacyl irciniasulfonic acids from a tropical Coscinoderma sp. sponge. |
| AID583083 | Activity of Escherichia coli BL21(DE3) VIM-2 W87A mutant beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID324294 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoR mutant assessed as cell count in log phase at 100 ug/ml after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1436941 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 12 hrs | 2017 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 27, Issue:4 | Quinolidene based monocarbonyl curcumin analogues as promising antimycobacterial agents: Synthesis and molecular docking study. |
| AID534386 | Antibacterial activity against Escherichia coli K-12 W1895 by microdilution method in presence of Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate. |
| AID1185773 | Antimicrobial activity against Escherichia coli ATCC 11229 assessed as inhibition zone after 24 hrs by agar well diffusion method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Discovery of diethyl 2,5-diaminothiophene-3,4-dicarboxylate derivatives as potent anticancer and antimicrobial agents and screening of anti-diabetic activity: synthesis and in vitro biological evaluation. Part 1. |
| AID572034 | Antibacterial activity against Clostridium bifermentans by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1774187 | Antibacterial activity against Escherichia coli delta fepA assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID200525 | Minimum inhibitory concentration against aerobic organism Salmonella schottmuelleri strain 2837 | 1982 | Journal of medicinal chemistry, Apr, Volume: 25, Issue:4 | Quaternary heterocyclylamino beta-lactams: a generic alternative to the classical acylamino side chain. |
| AID324219 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoU mutant assessed as cell count in stationary phase at 100 ug/ml after 1 day | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID556752 | Bactericidal activity against sodA gene-deficient Escherichia coli K-12 3144 after 18 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID530202 | Antimicrobial activity against Mycobacterium bovis BCG ML1010 carrying transposon IS1096::Km inserted at +43bp of ppe gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1265203 | Bactericidal activity against Bacillus subtilis ATCC 6633 after 24 hrs | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes. |
| AID1436575 | Antibacterial activity against Escherichia coli MTCC 443 by broth microdilution assay method | 2017 | Bioorganic & medicinal chemistry letters, 02-01, Volume: 27, Issue:3 | Synthesis, identification and in vitro biological evaluation of some novel quinoline incorporated 1,3-thiazinan-4-one derivatives. |
| AID369628 | Antimicrobial activity against beta-lactamase negative ampicillin-resistant Haemophilus influenzae by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Can the Etest correctly determine the MICs of beta-lactam and cephalosporin antibiotics for beta-lactamase-negative ampicillin-resistant Haemophilus influenzae? |
| AID1434050 | Antibacterial activity against Escherichia coli NCIM 2256 by standard agar method | 2017 | Bioorganic & medicinal chemistry letters, 02-01, Volume: 27, Issue:3 | Antileishmanial evaluation of clubbed bis(indolyl)-pyridine derivatives: One-pot synthesis, in vitro biological evaluations and in silico ADME prediction. |
| AID562384 | Antimicrobial activity against Enterococcus faecium clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID573335 | Antibacterial activity against ceftazidime-susceptible Enterobacteriaceae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID448150 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 at 10 ug after 18 hrs by well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis of some new 1,2,4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities. |
| AID472404 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry, Apr-15, Volume: 18, Issue:8 | Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives. |
| AID66383 | The compound was tested for minimal inhibitory concentration against Enterobacter sp. | 2002 | Bioorganic & medicinal chemistry letters, Sep-02, Volume: 12, Issue:17 | The activity of p-methoxybenzylisothiocyanate against Neisseria gonorrhoeae, Haemophilus ducreyi, and other microorganisms. |
| AID547173 | Antibacterial activity against Vibrio cholerae by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID573352 | Antibacterial activity against ceftazidime-susceptible Escherichia coli by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1423472 | Inhibition of refolded rhodanese (unknown origin) preincubated with Escherichia coli GroEL/GroES for 60 mins in absence of compound followed by compound addition by spectrometric analysis | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID558791 | Antimicrobial activity against Enterobacter cloacae assessed as percent susceptible isolates by CLSI method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007. |
| AID561442 | Antibacterial activity against Escherichia coli YD006 harboring beta-lactamase CMY-33 gene by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Reduced susceptibility to cefepime among Escherichia coli clinical isolates producing novel variants of CMY-2 beta-lactamase. |
| AID564832 | Bactericidal activity against methicillin-resistant coagulase-negative Staphylococcus sciuri after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1194188 | Antimicrobial activity against Sarcina ureae after 24 hrs by two fold serial microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 25, Issue:8 | Studies on antimicrobial effects of four ligands and their transition metal complexes with 8-mercaptoquinoline and pyridine terminal groups. |
| AID1594845 | Antibiofilm activity against Pseudomonas aeruginosa PAO1 assessed as inhibition of biofilm formation at 0.5 times MIC incubated for 24 hrs by crystal violet staining based ELISA method | 2019 | Journal of natural products, 06-28, Volume: 82, Issue:6 | Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. |
| AID587980 | Antibacterial activity against Escherichia coli AS226 carrying pBSDS237A mutant after 18 hrs by broth microdilution method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID395734 | Antimicrobial activity against imipenem-susceptible invasive nontypeable Haemophilus influenzae isolate 248 by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | First characterization of heterogeneous resistance to imipenem in invasive nontypeable Haemophilus influenzae isolates. |
| AID1287515 | Antibacterial activity against Staphylococcus aureus NCIM 2010 after 12 hrs | 2016 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 26, Issue:7 | Synthesis, biological evaluation and molecular docking study of some novel indole and pyridine based 1,3,4-oxadiazole derivatives as potential antitubercular agents. |
| AID546932 | Antibacterial activity against Salmonella enterica serovar Typhi assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID293865 | Antimicrobial activity against Escherichia coli ATCC 25922 after 24 hrs by two fold dilution method | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6 | Synthesis of pseudopeptides based L-tryptophan as a potential antimicrobial agent. |
| AID278252 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS3 with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1141104 | Antimicrobial activity against Escherichia coli ATCC 25922 after 24 to 48 hrs by two-fold broth microdilution method | 2014 | Bioorganic & medicinal chemistry, May-15, Volume: 22, Issue:10 | Exploring 5-nitrofuran derivatives against nosocomial pathogens: synthesis, antimicrobial activity and chemometric analysis. |
| AID551083 | Antibacterial activity against Bacillus subtilis at 1000 ug/mL after 72 hrs by agar diffusion assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1 | 3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents. |
| AID255525 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 4.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID559859 | Antimicrobial activity against Streptococcus agalactiae clinical isolates by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections. |
| AID66247 | Minimum inhibitory concentration against aerobic organism Enterobacter cloacae 2646 | 1982 | Journal of medicinal chemistry, Apr, Volume: 25, Issue:4 | Quaternary heterocyclylamino beta-lactams: a generic alternative to the classical acylamino side chain. |
| AID508595 | Antibacterial activity against wild type Salmonella enteritidis 5408 harboring gyrA D87Y mutant gene by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Fitness costs and stability of a high-level ciprofloxacin resistance phenotype in Salmonella enterica serotype enteritidis: reduced infectivity associated with decreased expression of Salmonella pathogenicity island 1 genes. |
| AID585433 | Antimicrobial activity against Escherichia coli DH5[alpha] by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID527631 | Antimicrobial activity against Micrococcus luteus IFO 12708 after 24 hrs by broth dilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Bromophenols as Candida albicans isocitrate lyase inhibitors. |
| AID278533 | Antimicrobial activity against Bifidobacterium breve R0070 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID564816 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID527630 | Antimicrobial activity against Bacillus subtilis ATCC 6633 after 24 hrs by broth dilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Bromophenols as Candida albicans isocitrate lyase inhibitors. |
| AID1721973 | Antibacterial activity against Erwinia amylovora by microdilution method | 2020 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 30, Issue:17 | New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. |
| AID1055947 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 16 hrs | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID425867 | Antimicrobial activity against Carnobacterium divergens BM4490 expressing beta-lactamase CAD1 at 0.5 McFarland inoculum size by E-test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens. |
| AID534999 | Antimicrobial activity against Clostridium cocleatum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID644179 | Antibacterial activity against Escherichia coli ATCC 35210 treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID318715 | Antimicrobial activity against Streptococcus pyogenes by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID520992 | Antimicrobial activity against Brucella suis ATCC 23445 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Novel antimicrobial peptides that exhibit activity against select agents and other drug resistant bacteria. |
| AID206082 | In vitro inhibitory activity against Streptococci EryRi (98);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID655618 | Antibacterial activity against Escherichia coli ATCC 35218 at 40 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID420214 | Antimicrobial activity against Micrococcus luteus UFPEDA 06 after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID1908119 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID582914 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61G mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID681114 | TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in SKPT cells | 2005 | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Jan, Volume: 59, Issue:1 | Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1. |
| AID633492 | Antifungal activity against Aspergillus fumigatus HIC 6094 after 48 to 72 hrs by two fold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial activity of brominated resorcinol dimers. |
| AID442427 | Antimicrobial activity against Escherichia coli after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID495752 | Antimicrobial activity against Escherichia coli J5 transconjugants expressing beta lactamase CTX-M-9 isolated from human flora associated C3H rat infected with Salmonella enterica serotype Virchow and treated with Cefixime by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID758268 | Antifungal activity against Trichophyton rubrum MTCC 296 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Design and synthesis of biquinolone-isoniazid hybrids as a new class of antitubercular and antimicrobial agents. |
| AID1293899 | Antibacterial activity against Pseudomonas fluorescens after 18 hrs by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9 | Novel tetrazoloquinoline-rhodanine conjugates: Highly efficient synthesis and biological evaluation. |
| AID1491154 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by CLSI method | 2017 | Journal of natural products, 05-26, Volume: 80, Issue:5 | Antimicrobial Spirotetronate Metabolites from Marine-Derived Micromonospora harpali SCSIO GJ089. |
| AID548038 | Antimicrobial activity against Escherichia coli DH10B by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID529624 | Antibacterial activity against Beta-lactamase negative Haemophilus influenzae isolate harboring fst1 mutant gene after 20 to 24 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID535340 | Antimicrobial activity against Streptococcus pneumoniae clinical isolates by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Antimicrobial resistance among respiratory pathogens in Spain: latest data and changes over 11 years (1996-1997 to 2006-2007). |
| AID668094 | Antibacterial activity against Bacillus subtilis NBRC 3134 after overnight incubation by microdilution method | 2012 | Journal of natural products, Apr-27, Volume: 75, Issue:4 | Phenanthrene derivatives from Cymbidium Great Flower Marie Laurencin and their biological activities. |
| AID1183255 | Antimicrobial activity against Clostridium tetani MTCC 449 assessed as absence of visible growth after 24 to 48 hrs by broth micro dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis and characterization of fluoro substituted novel pyrazolylpyrazolines scaffold and their pharmacological screening. |
| AID1399497 | Antibacterial activity against Salmonella typhimurium ATCC 13311 after 24 hrs by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID1388197 | Antibacterial activity against Escherichia coli MTCC 443 at 100 ug/ml incubated for 12 hrs by agar disc diffusion assay | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18 | Synthesis, antimicrobial activity, structure-activity relationship and cytotoxic studies of a new series of functionalized (Z)-3-(2-oxo-2-substituted ethylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ones. |
| AID1546101 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs by agar disk diffusion method | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID1774193 | Antibacterial activity against Escherichia coli delta fepA delta cirA delta fiu assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID583088 | Ratio of Kcat to Km for Escherichia coli XL1-Blue wild-type IMP-1 beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID557414 | Antimicrobial activity in Bacteroides thetaiotaomicron by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1126668 | Antibacterial activity against Clostridium tetani MTCC 449 assessed as growth inhibition after 24 to 48 hrs by broth microdilution method | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Synthesis, characterization and pharmacological screening of some novel 5-imidazopyrazole incorporated polyhydroquinoline derivatives. |
| AID559349 | Antimicrobial activity against Salmonella spp. harboring tem-like gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID532987 | Antibacterial activity against Pseudomonas aeruginosa NCIM 5029 in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID1185310 | Antibacterial activity Staphylococcus aureus ATCC-25923 assessed as growth inhibition after 24 hrs by twofold serial dilution technique | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis and 3D-QSAR studies of new diphenylamine containing 1,2,4-triazoles as potential antitubercular agents. |
| AID1471212 | Antibacterial activity against Klebsiella pneumoniae ATCC 27736 by spectrophotometric method | 2017 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 27, Issue:13 | Diversity-oriented sustainable synthesis of antimicrobial spiropyrrolidine/thiapyrrolizidine oxindole derivatives: New ligands for a metallo-β-lactamase from Klebsiella pneumonia. |
| AID324223 | Antibacterial activity against Escherichia coli K12 containing PhoU mutant assessed as cell count in stationary phase at 100 ug/ml after 3 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID556590 | Bactericidal activity against sodB gene-deficient Escherichia coli K-12 DK after 18 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID750273 | Antifungal activity against Aspergillus clavatus MTCC 1323 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. |
| AID1408106 | Antibacterial activity against Escherichia coli ATCC 12435 after 24 hrs by two-fold serial dilution method | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157 | Design, synthesis, antimicrobial, antiquorum-sensing and antitumor evaluation of new series of pyrazolopyridine derivatives. |
| AID613609 | Antibacterial activity against 10'8 CFU/mL Bacillus subtilis MTCC 441 by NCCLS M100-S12(M7) broth microdilution method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis and identification of β-aryloxyquinolines and their pyrano[3,2-c]chromene derivatives as a new class of antimicrobial and antituberculosis agents. |
| AID555452 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 21 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID519991 | Antimicrobial activity against vancomycin-resistant Enterococcus faecalis nosocomial isolate | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens. |
| AID533412 | Antimicrobial activity against Finegoldia magna assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID736391 | Antibacterial activity against Serratia plymuthica C48 by paper disk diffusion method | 2013 | Journal of natural products, Jan-25, Volume: 76, Issue:1 | Antibacterial and antiplasmodial constituents of Beilschmiedia cryptocaryoides. |
| AID424717 | Antifungal activity against Mucor miehei | 2009 | Journal of natural products, Apr, Volume: 72, Issue:4 | Limazepines A-F, pyrrolo[1,4]benzodiazepine Antibiotics from an Indonesian Micrococcus sp. |
| AID519662 | Antimicrobial activity against Escherichia coli EPI300 harboring GM2995 pCC1-1224 carrying CTX-M-3 beta-lactamase gene from by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID1604670 | Antibacterial activity against Salmonella enterica 87 by visual method | |||
| AID563968 | Antibacterial activity against Escherichia coli TOP10 harboring beta-lactamase NDM-1 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. |
| AID572244 | Antibacterial activity against Streptococcus anginosus by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID495329 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with Ala502Val, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID565670 | Antimicrobial activity against beta-lactamase positive (amoxicillin)clavulanate-resistant Haemophilus influenzae assessed as susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID405817 | Antimicrobial activity against Pseudomonas putida 12346 isolate harboring bla IMP-1 carrying integron In86 containing aminoglycoside resistance gene aac(6')-3 | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital. |
| AID495749 | Antimicrobial activity against Salmonella enterica serotype Virchow 3464b by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID548024 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237H mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID551086 | Antibacterial activity against Escherichia coli at 1000 ug/mL after 72 hrs by agar diffusion assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1 | 3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents. |
| AID420221 | Antimicrobial activity against multidrug-resistant Staphylococcus aureus H.C. 20489 isolate after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID255557 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 128.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID572258 | Antibacterial activity against Prevotella buccae by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID420228 | Antimicrobial activity against coagulase-negative Staphylococcus H.A.M. 278 isolate after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID559581 | Antimicrobial activity against Chlamydophila pneumoniae infected in Vero cells | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic susceptibility of Waddlia chondrophila in Acanthamoeba castellanii amoebae. |
| AID562334 | Antimicrobial activity against Escherichia coli DH5alpha harboring plasmid pBC-SK after 18 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso. |
| AID562596 | Antimicrobial activity against Enterococcus faecalis clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID519120 | Antibacterial activity against Proteus mirabilis M 12 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID1265194 | Antibacterial activity against Klebsiella pneumoniae ATCC 43816 after 24 hrs by microtiter plate method | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes. |
| AID360075 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as tetra-aspartate-tetra-aspartate-tetra-aspartate multimer containing D-Ala4 to D-Asp-L-Lys3 cross links at 128 ug/ml by mass spectrometry | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID750277 | Antibacterial activity against Staphylococcus aureus MTCC 96 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. |
| AID249986 | Minimum inhibitory concentration against Bacillus subtilis | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Studies on synthesis and evaluation of quantitative structure-activity relationship of 5-[(3'-chloro-4',4'-disubstituted-2-oxoazetidinyl)(N-nitro)amino]-6-hydroxy-3-alkyl/aryl[1,3]azaphospholo[1,5-a]pyridin-1-yl-phosphorus dichlorides. |
| AID535679 | Antimicrobial activity against beta-lactamase negative Haemophilus influenzae expressing fst1 gene assessed as resistant isolates by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Genotypic versus phenotypic characterization, with respect to beta-lactam susceptibility, of Haemophilus influenzae isolates exhibiting decreased susceptibility to beta-lactam resistance markers. |
| AID735977 | Antimicrobial activity against Bacillus subtilis after 24 hrs by microdilution susceptibility test | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Synthesis and antimicrobial activity of some new benzo and naphthonitrile derivatives. |
| AID255532 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 32.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID1286489 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 25923 after 20 to 24 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID1347488 | Antibacterial activity against Staphylococcus aureus assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID528528 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B10 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID1706152 | Antibacterial activity against Enterococcus faecalis ATCC 29212 assessed as reduction in bacterial growth incubated for 18 hrs by CLSI based broth microdilution assay | |||
| AID547790 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237M mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID567471 | Antimicrobial activity against gLow-BLNAR Haemophilus influenzae by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | In vitro activity of tebipenem, a new oral carbapenem antibiotic, against beta-lactamase-nonproducing, ampicillin-resistant Haemophilus influenzae. |
| AID584467 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus vitulinus SVMP03 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID534733 | Antimicrobial activity against Bacteroides uniformis by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1888848 | Antibacterial activity against Staphylococcus aureus K1758 measured after 24 hrs by Muller Hinton broth based MTT assay | 2022 | Bioorganic & medicinal chemistry, 01-15, Volume: 54 | Potentiating the intracellular killing of Staphylococcus aureus by dihydroquinazoline analogues as NorA efflux pump inhibitor. |
| AID400382 | Antibacterial activity against Staphylococcus aureus at 200 ug/100uL after 24 hrs by agar well diffusion method | 1998 | Journal of natural products, Feb, Volume: 61, Issue:2 | Antibacterial steroidal alkaloids from Sarcococca saligna. |
| AID528530 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B40 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID535437 | Antimicrobial activity against Eubacterium rectale by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID442416 | Antimicrobial activity against Bacillus cereus at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID562383 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecium clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1056538 | Antibacterial activity against Aeromonas hydrophila ATCC 7966 by broth microdilution method | 2013 | Journal of natural products, Dec-27, Volume: 76, Issue:12 | Cytotoxic and antibacterial marfuraquinocins from the deep South China Sea-derived Streptomyces niveus SCSIO 3406. |
| AID487476 | Antibacterial activity against Klebsiella pneumoniae NCIM 2957; ATCC 11298 at 100 mg/ml after 24 hrs by agar cup plate method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Design, synthesis, characterization, and antibacterial activity of {5-chloro-2-[(3-substitutedphenyl-1,2,4-oxadiazol-5-yl)-methoxy]-phenyl}-(phenyl)-methanones. |
| AID1286509 | Antibacterial activity against Escherichia coli ATCC 25922 after 20 to 24 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID525549 | Antimicrobial activity against ampicillin resistant nontypeable Haemophilus influenzae isolate BB1052 harboring with plasmid pB1000 bearing beta-lactamase ROB-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Haemophilus influenzae clinical isolates with plasmid pB1000 bearing blaROB-1: fitness cost and interspecies dissemination. |
| AID382724 | Antimicrobial activity against Aspergillus sp. at 572.4 uM by disc-diffusion method | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives. |
| AID1868104 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolate 3B assessed as inhibition of visible bacterial growth incubated for 18 hrs by CLSI protocol based assay | 2022 | Journal of natural products, 05-27, Volume: 85, Issue:5 | Enceleamycins A-C, Furo-Naphthoquinones from |
| AID264077 | Antibacterial activity against Escherichia coli ATCC 445 | 2006 | Bioorganic & medicinal chemistry letters, May-01, Volume: 16, Issue:9 | Studies on synthesis and evaluation of quantitative structure-activity relationship of 10-methyl-6-oxo-5-arylazo-6,7-dihydro-5H-[1,3]azaphospholo[1,5-d][1,4]benzodiazepin-2-phospha-3-ethoxycarbonyl-1-phosphorus dichlorides. |
| AID495324 | Antimicrobial activity against Beta-lactamase-positive, ampicillin-cluvulanate-resistant Haemophilus influenzae by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID567282 | Ratio of Kcat to Km for Acinetobacter baumannii ADC-11 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Extended-spectrum cephalosporinase in Acinetobacter baumannii. |
| AID565002 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus hominis assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID544275 | Antimicrobial activity against Enterococcus faecalis NKH5 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1055635 | Antibacterial activity against Escherichia coli MTCC 443 assessed as growth inhibition at 1 mg/mL after 24 hrs by two-fold serial dilution method | 2013 | European journal of medicinal chemistry, , Volume: 70 | Synthesis and antimicrobial activity of some novel hydrazide, benzochromenone, dihydropyridine, pyrrole, thiazole and thiophene derivatives. |
| AID562219 | Antimicrobial activity against Desulfovibrio sp. in presence of Sulbactam by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID572024 | Antibacterial activity against Clostridium bolteae by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID535691 | Antimicrobial activity against beta-lactamase CTX-M-15-producing fluoroquinolone-resistant Escherichia coli FMV5825 expressing qnrB2 and aac(6')-Ib-cr and harboring gyrA Ser83Ile and Asp87Asn mutant gene and ParC Ser80Ile and Glu84Val mutant gene obtained | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog. |
| AID582906 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87A mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID426125 | Antimicrobial activity against Yersinia pseudotuberculosis ATCC 911 at 10 ug after 18 hrs by agar-well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities. |
| AID585869 | Antimicrobial activity against Pseudomonas aeruginosa isolate 15 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1143593 | Antibacterial activity against Pseudomonas aeruginosa assessed as growth inhibition after 24 hrs by two fold serial dilution method | 2014 | European journal of medicinal chemistry, Jun-23, Volume: 81 | Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-arylethanones: antibacterial, DNA photocleavage, and anticancer activities. |
| AID1326387 | Antibacterial activity against Bacillus subtilis P10C derived after 10 passage in presence of JBIR-100 after 16 to 18 hrs by microbroth dilution assay | 2016 | Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24 | Biological characterization of the hygrobafilomycin antibiotic JBIR-100 and bioinformatic insights into the hygrolide family of natural products. |
| AID644172 | Antibacterial activity against Staphylococcus aureus ATCC 6538 treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID318706 | Antimicrobial activity against Sarcina lutea by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID1551859 | Antibacterial activity against Pseudomonas aeruginosa | 2019 | European journal of medicinal chemistry, Jul-15, Volume: 174 | 1,2,4-Triazole-quinoline/quinolone hybrids as potential anti-bacterial agents. |
| AID572225 | Antibacterial activity against Coprobacillus cateniformis by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID382726 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by microdilution assay | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives. |
| AID278542 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium longum P/N 601377 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID534088 | Antibacterial activity against penicillin-susceptible Streptococcus pneumoniae isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro activity of ceftaroline against Streptococcus pneumoniae isolates exhibiting resistance to penicillin, amoxicillin, and cefotaxime. |
| AID595440 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by by twofold serial dilution method | 2011 | Journal of natural products, Apr-25, Volume: 74, Issue:4 | Scalarane sesterterpenes from the sponge Hyatella sp. |
| AID1870141 | Antibacterial activity against wild type Staphylococcus aureus 4463/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID590287 | Antifungal activity against Aspergillus fumigatus HIC 6094 at 100 ug/ml after 2 weeks | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase. |
| AID1105401 | Antibacterial activity against Bacillus pumilus MTCC 2466 assessed as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID1114120 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition by broth microdilution method | 2013 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, May, Volume: 22, Issue:5 | Microbiologically active Mannich bases derived from 1,2,4-triazoles. The effect of C-5 substituent on antibacterial activity. |
| AID285339 | Antimicrobial activity against streptomycin-resistant Escherichia coli J53 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First report of plasmid-mediated qnrA1 in a ciprofloxacin-resistant Escherichia coli strain in Latin America. |
| AID389006 | Antifungal activity against Candida maltosa SBUG 700 assessed as diameter of the inhibition zone at 1 uM/disk by disk diffusion method | 2008 | Bioorganic & medicinal chemistry, Dec-01, Volume: 16, Issue:23 | Hetero-Diels-Alder reaction of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with arylsulfonylcyanides. Synthesis and antimicrobial activity of 4-hydroxy-2-(arylsulfonyl)pyridines. |
| AID595437 | Antibacterial activity against Proteus vulgaris ATCC 3851 after 24 hrs by by twofold serial dilution method | 2011 | Journal of natural products, Apr-25, Volume: 74, Issue:4 | Scalarane sesterterpenes from the sponge Hyatella sp. |
| AID1352295 | Antibacterial activity against Escherichia coli ATCC 25922 at 30 ug/disk | 2018 | European journal of medicinal chemistry, Feb-10, Volume: 145 | Bysspectin A, an unusual octaketide dimer and the precursor derivatives from the endophytic fungus Byssochlamys spectabilis IMM0002 and their biological activities. |
| AID463407 | Antimicrobial activity against Klebsiella pneumoniae at 1000 ug after 24 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines. |
| AID444058 | Volume of distribution at steady state in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID558324 | Antibacterial activity against bla gene-negative and nitrocefin reaction-negative beta-lactamase harboring Campylobacter jejuni isolate P835 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID1079949 | Proposed mechanism(s) of liver damage. [column 'MEC' in source] | |||
| AID547785 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237L mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID530201 | Antimicrobial activity against Mycobacterium bovis BCG ML1075 carrying transposon IS1096::Km inserted at +899bp of gca gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID534959 | Antimicrobial activity against Prevotella bivia by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID293869 | Antimicrobial activity against Proteus vulgaris CMCC(B) 49001 after 24 hrs by two fold dilution method | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6 | Synthesis of pseudopeptides based L-tryptophan as a potential antimicrobial agent. |
| AID533406 | Antimicrobial activity against Clostridium tertium by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID1399265 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID539558 | Antimicrobial activity against Salmonella Typhimurium ATCC 14028 | 2010 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 20, Issue:23 | Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase. |
| AID1896843 | Antibacterial activity against Shigella flexneri CMCC51572 assessed as prevention of visible growth by broth microdilution method | |||
| AID572036 | Antibacterial activity against Clostridium celerecrescens by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1905202 | Antibacterial activity against MDR-methicillin-resistant Staphylococcus aureus ATCC BAA-44 assessed as reduction in bacterial growth measured after 18 hrs by broth microdilution method | 2022 | Journal of medicinal chemistry, 04-14, Volume: 65, Issue:7 | Spermine-Conjugated Short Proline-Rich Lipopeptides as Broad-Spectrum Intracellular Targeting Antibacterial Agents. |
| AID736392 | Antibacterial activity against Pseudomonas stutzeri A1501 by paper disk diffusion method | 2013 | Journal of natural products, Jan-25, Volume: 76, Issue:1 | Antibacterial and antiplasmodial constituents of Beilschmiedia cryptocaryoides. |
| AID530428 | Antimicrobial activity against Mycobacterium smegmatis overexpressing rv0194 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID564805 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID420224 | Antimicrobial activity against multidrug-resistant Enterococcus faecalis H.C. 21752 isolate after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID534086 | Antibacterial activity against levofloxacin-resistant Streptococcus pneumoniae isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro activity of ceftaroline against Streptococcus pneumoniae isolates exhibiting resistance to penicillin, amoxicillin, and cefotaxime. |
| AID463415 | Antimicrobial activity against Escherichia coli after 24 hrs by liquid dilution method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines. |
| AID1126670 | Antibacterial activity against Salmonella typhi MTCC 98 assessed as growth inhibition after 24 to 48 hrs by broth microdilution method | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Synthesis, characterization and pharmacological screening of some novel 5-imidazopyrazole incorporated polyhydroquinoline derivatives. |
| AID1695864 | Antibacterial activity against Flavobacterium devorans ATCC 10829 incubated for 24 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID547993 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237Y mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID558329 | Antibacterial activity against bla gene-positive and nitrocefin reaction-positive beta-lactamase harboring Campylobacter jejuni isolate P305 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID278254 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS3 acrAB::Kan with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID299661 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 25923 by broth microdilution method | 2007 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 17, Issue:15 | Synthesis and evaluation of amphiphilic cationic quinine-derived for antibacterial activity against methicillin-resistant Staphylococcus aureus. |
| AID1471038 | Growth inhibition of Pseudomonas fluorescens NCIM 2059 at 1 ug/ml measured after 8 hrs relative to control | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID278565 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium longum R0175 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID536087 | Antimicrobial activity against Staphylococcus aureus IFO 3060 after 24 hrs | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID541856 | Antimicrobial activity against florfenicol-resistant Edwardsiella ictaluri M07-1 by microdilution assay | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | IncA/C plasmid-mediated florfenicol resistance in the catfish pathogen Edwardsiella ictaluri. |
| AID585425 | Antimicrobial activity against oqxAB positive Escherichia coli C600 G375-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID585420 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W191-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID324996 | Antibacterial activity against Haemophilus paraphrophilus ATCC 29241 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID395351 | Antibacterial activity against Klebsiella pneumoniae UC57 at 1 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID558798 | Antimicrobial activity against extended spectrum beta-lactamase-deficient Escherichia coli assessed as percent susceptible isolates by CLSI method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007. |
| AID758273 | Antibacterial activity against Escherichia coli MTCC 443 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Design and synthesis of biquinolone-isoniazid hybrids as a new class of antitubercular and antimicrobial agents. |
| AID584327 | Antibacterial activity against speE deficient Escherichia coli JW0117-1 | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Interplay between drug efflux and antioxidants in Escherichia coli resistance to antibiotics. |
| AID251620 | inhibition of Escherichia coli was measured by zone diameter | 2004 | Bioorganic & medicinal chemistry letters, Dec-06, Volume: 14, Issue:23 | Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: a structure-activity evaluation study. |
| AID1056536 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolate shhs-A1 by broth microdilution method | 2013 | Journal of natural products, Dec-27, Volume: 76, Issue:12 | Cytotoxic and antibacterial marfuraquinocins from the deep South China Sea-derived Streptomyces niveus SCSIO 3406. |
| AID750279 | Antibacterial activity against Escherichia coli MTCC 443 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. |
| AID662989 | Antibacterial activity against Bacillus subtilis MTCC 441 by macrobroth dilution assay | 2012 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 22, Issue:12 | An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidines. |
| AID565682 | Antimicrobial activity against beta-lactamase-positive ampicillin-resistant Haemophilus influenzae harboring fst1 mutant gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID324164 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 at 100 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID674909 | Antibacterial activity against Staphylococcus aureus MTCC 96 | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17 | Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives. |
| AID1535458 | Effect on cell viability of Paracoccus sp. 4M6 at 5 uM measured after 6 hrs by resazurin dye based fluorescence assay | 2019 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 29, Issue:4 | Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds? |
| AID519115 | Antibacterial activity against Proteus mirabilis NP37 after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID585679 | Antimicrobial activity against ampGh1 deficient Pseudomonas aeruginosa PAK after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1164942 | Antimicrobial activity against methicillin-sensitive Staphylococcus aureus ATCC 29213 by microbroth dilution method | 2014 | Journal of medicinal chemistry, Oct-23, Volume: 57, Issue:20 | Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives. |
| AID294187 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 by macro-broth dilution assay | 2007 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 17, Issue:8 | Synthesis and antimicrobial activity of some novel phenyl and benzimidazole substituted benzyl ethers. |
| AID1769962 | Antibacterial activity against Escherichia coli ATCC25922 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID372547 | Antibacterial activity against genetically beta-lactamase-negative ampicillin-susceptible Haemophilus influenzae type b without amino acid substitutions in ftsI gene and bla gene by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID535637 | Antimicrobial activity against Group B streptococcus serotype Ib R3 harboring Q557E, A400V mutations in PBP 2X and T567I, G539E mutations in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID564808 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus simulans after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1877435 | Antibacterial activity against Escherichia coli | 2022 | Bioorganic & medicinal chemistry letters, 01-01, Volume: 55 | New bis- and tetrakis-1,2,3-triazole derivatives: Synthesis, DNA cleavage, molecular docking, antimicrobial, antioxidant activity and acid dissociation constants. |
| AID495341 | Antimicrobial activity against Beta-lactamase-positive, ampicillin-cluvulanate-resistant Haemophilus influenzae with Asp350Asn, Met377Ile, Ser385Thr, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID557442 | Antimicrobial activity in Prevotella buccae by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID632566 | Antifungal activity against Penicillium chrysogenum at 200 ug/mL after 48 hrs by agar cup diffusion assay | 2011 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 21, Issue:24 | A new antifungal briarane diterpenoid from the gorgonian Junceella juncea Pallas. |
| AID1399275 | Antimicrobial activity against Escherichia coli isolate SJ 3 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID763997 | Antibacterial activity against Shigella flexneri ATCC 15391 assessed as diameter of inhibition zone at 1 mg/ml after 24 hrs by cup diffusion method (Rvb = 17 mm) | 2013 | European journal of medicinal chemistry, Aug, Volume: 66 | Synthesis, biological evaluation and molecular docking studies of some pyrimidine derivatives. |
| AID324218 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoU mutant assessed as cell count in log phase at 100 ug/ml after 1 day | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID573343 | Antibacterial activity against ceftazidime-nonsusceptible Citrobacter freundii by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1265690 | Antibiofilm activity against Pseudoalteromonas lipolytica TC8 assessed as reduction in adhesion after 15 hrs by Syto61 based-fluorescence analysis relative to control | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Click-based synthesis of bromotyrosine alkaloid analogs as potential anti-biofilm leads for SAR studies. |
| AID1535444 | Anti-biofilm activity against Pseudoalteromonas ulvae TC14 assessed as bacterial adhesion at 200 uM incubated for 15 hrs at 20 degC by Syto 61 dye based fluorescence assay relative to control | 2019 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 29, Issue:4 | Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds? |
| AID1347490 | Antibacterial activity against Pseudomonas aeruginosa assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID555256 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 69 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1399489 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID389389 | Antibacterial activity against Escherichia coli ATCC 11775 | 2008 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 18, Issue:20 | Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp. |
| AID587197 | Antimicrobial activity against Candida albicans after 18 hrs by broth microdilution method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Comazaphilones A-F, azaphilone derivatives from the marine sediment-derived fungus Penicillium commune QSD-17. |
| AID547998 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237C mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID1157882 | Antimicrobial activity against Kocuria rhizophila NBRC 12708 after 24 hrs by two-fold broth dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Suvanine sesterterpenes and deacyl irciniasulfonic acids from a tropical Coscinoderma sp. sponge. |
| AID1648084 | Antibacterial activity against Enterococcus faecalis ATCC 19433 assessed as reduction in microbial growth after 24 hrs by two-fold serial dilution method | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Absolute Configuration and Antibiotic Activity of Piceamycin. |
| AID392751 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 431300 after 18 to 24 hrs by tube dilution method | 2009 | Bioorganic & medicinal chemistry, Feb-15, Volume: 17, Issue:4 | Synthesis and antimicrobial evaluation of some new substituted purine derivatives. |
| AID529587 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-1 assessed as bacterial density at 512 ug/ml after 18 hrs | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID519010 | Activity of Beta-lactamase TEM-149 T182M mutant expressed in Escherichia coli HB101 | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | E240V substitution increases catalytic efficiency toward ceftazidime in a new natural TEM-type extended-spectrum beta-lactamase, TEM-149, from Enterobacter aerogenes and Serratia marcescens clinical isolates. |
| AID510172 | Antimicrobial activity against Bacillus subtilis ATCC 6633 by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID529304 | Antimicrobial activity against Acinetobacter baumannii isolate Ac058 expressing beta-lactamase Oxa-58 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate. |
| AID536145 | Antimicrobial activity against Escherichia coli ATCC 25922 after 24 hrs by serial dilution method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Design, synthesis and in vitro evaluation of antitubercular and antimicrobial activity of some novel pyranopyrimidines. |
| AID532677 | Antimicrobial activity against ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates assessed as intermediate resistant isolates by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Emergence of ciprofloxacin-nonsusceptible Streptococcus pyogenes isolates from healthy children and pediatric patients in Portugal. |
| AID547775 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237A mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID562328 | Antimicrobial activity against Chryseobacterium indologenes 597 expressing metallo-beta-lactamase IND-6 after 18 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso. |
| AID674908 | Antibacterial activity against Bacillus subtilis MTCC 441 | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17 | Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives. |
| AID525546 | Antimicrobial activity against Haemophilus influenzae Rd KW20 harboring with plasmid pB1000 bearing beta-lactamase ROB-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Haemophilus influenzae clinical isolates with plasmid pB1000 bearing blaROB-1: fitness cost and interspecies dissemination. |
| AID583433 | Antimicrobial activity against beta-lactam-resistant and chromosomal mecA deficient Staphylococcus aureus CRB harboring PBP4 E183A F241R, GdpP N182K and AcrB I960V mutant genes selected after 21 days of serial passage in ceftobiprole | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | A mecA-negative strain of methicillin-resistant Staphylococcus aureus with high-level β-lactam resistance contains mutations in three genes. |
| AID1281308 | Antibacterial activity against Bacillus subtilis at 50 mM after 16 to 24 hrs by disk diffusion assay | 2016 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 26, Issue:5 | Synthesis and SAR of 4-methyl-5-pentylbenzene-1,3-diol (MPBD), produced by Dictyostelium discoideum. |
| AID1594844 | Bactericidal activity against Escherichia coli ATCC 35210 by microdilution method | 2019 | Journal of natural products, 06-28, Volume: 82, Issue:6 | Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. |
| AID535185 | Antimicrobial activity against Clostridium fallax by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1132044 | Antibacterial activity against Bacillus subtilis | 1978 | Journal of medicinal chemistry, Jan, Volume: 21, Issue:1 | Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. |
| AID313666 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1 | Antimicrobial activities of the bromophenols from the red alga Odonthalia corymbifera and some synthetic derivatives. |
| AID567475 | Antimicrobial activity against gBLPACR-2 Haemophilus influenzae by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | In vitro activity of tebipenem, a new oral carbapenem antibiotic, against beta-lactamase-nonproducing, ampicillin-resistant Haemophilus influenzae. |
| AID723714 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID1303883 | Antibacterial activity against methicillin resistant Staphylococcus aureus subsp. aureus HPV107 (ATCC BAA-44) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID585423 | Antimicrobial activity against oqxAB positive Escherichia coli C600 G262-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID373333 | Antibacterial activity against Staphylococcus aureus ATCC 25923 at 10 ug/disk after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID633860 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID324301 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoB mutant assessed as cell count in stationary phase at 100 ug/ml after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID419826 | Antibacterial activity against Bacillus subtilis MTCC 619 at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Jun, Volume: 44, Issue:6 | Physicochemical and biological characterization of novel macrocycles derived from o-phthalaldehyde. |
| AID573376 | Antibacterial activity against imipenem-susceptible Acinetobacter by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1266796 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs at 37 degC by broth dilution method | 2015 | Journal of natural products, Nov-25, Volume: 78, Issue:11 | Meroterpenoids from a Tropical Dysidea sp. Sponge. |
| AID582902 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87G mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID572027 | Antibacterial activity against Clostridium hathewayi by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID371354 | Antibacterial activity against Proteus vulgaris ATCC 3851 after 24 hrs | 2009 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 19, Issue:3 | Synthesis and antimicrobial activities of halogenated bis(hydroxyphenyl)methanes. |
| AID653693 | Binding affinity to human recombinant Tie2 by SPR assay | 2012 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 22, Issue:7 | Discovery of loperamide as an antagonist of angiopoietin1 and angiopoietin2 by virtual screening. |
| AID330983 | Antimicrobial activity against Pseudomonas aeruginosa 27853 | 2007 | Nature, May-03, Volume: 447, Issue:7140 | PTC124 targets genetic disorders caused by nonsense mutations. |
| AID1870148 | Antibacterial activity against wild type Staphylococcus aureus 4566/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID565016 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID555210 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 103 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID436286 | Antibacterial activity against Proteus vulgaris ATCC 3851 after 24 hrs by twofold dilution method | 2008 | Journal of natural products, Nov, Volume: 71, Issue:11 | Scalarane sesterterpenes from the sponge Smenospongia sp. |
| AID622559 | Antimicrobial activity against Bacillus subtilis MTCC 441 for 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 21, Issue:20 | Microwave assisted synthesis and antimicrobial evaluation of new fused pyran derivatives bearing 2-morpholinoquinoline nucleus. |
| AID1286494 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 6538 after 20 to 24 hrs in presence of 50% heat inactivated bovine serum | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID765556 | Antimicrobial activity against Bacillus cereus 702 Roma after 18 to 24 hrs by double microdilution method | 2013 | European journal of medicinal chemistry, Sep, Volume: 67 | Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities. |
| AID543806 | Bactericidal activity against Acinetobacter baumannii VT 126 assessed as eradication of pre-formed biofilm at 50 times MIC after 24 hrs by serial dilution | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID1328387 | Antibacterial activity against Escherichia coli after 24 hrs by MTT based microdilution assay | 2016 | Journal of natural products, 09-23, Volume: 79, Issue:9 | Total Synthesis of (±)-Isoperbergins and Correction of the Chemical Structure of Perbergin. |
| AID1402051 | Antibacterial activity against Acinetobacter baumannii ATCC 17978 after 18 to 20 hrs by spectrophotometry based microdilution method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid. |
| AID495339 | Antimicrobial activity against Beta-lactamase-positive, ampicillin-cluvulanate-resistant Haemophilus influenzae with Asp350Asn, Ser357Asp, Met377Ile, Ser385Thr, Arg517His substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID564891 | Antibacterial activity against ompF-deficient Escherichia coli AG100 at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID1328386 | Antibacterial activity against Pseudomonas aeruginosa after 24 hrs by MTT based microdilution assay | 2016 | Journal of natural products, 09-23, Volume: 79, Issue:9 | Total Synthesis of (±)-Isoperbergins and Correction of the Chemical Structure of Perbergin. |
| AID1411628 | Antibacterial activity against Enterobacter cloacae after 24 hrs by microdilution method | |||
| AID640494 | Antibacterial activity against Bacillus subtilis ATCC 6633 | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2 | Bioactive lipids from the sponge Spirastrella abata. |
| AID723721 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID1698866 | Antimicrobial activity against Staphylococcus aureus ATCC 12600 assessed as zone of inhibition at 2 mg/ml after 24 hrs by agar well diffusion method | 2020 | Journal of natural products, 10-23, Volume: 83, Issue:10 | Synthesis of Natural and Unnatural Quinolones Inhibiting the Growth and Motility of Bacteria. |
| AID1551785 | Antibacterial activity against Bacillus subtilis | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID285200 | Antimicrobial activity against Escherichia coli M103 mutant with AG100 lon3::IS186 acrR-acrAB genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID420215 | Antimicrobial activity against Enterococcus faecalis UFPEDA 138 after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID557797 | Antimicrobial activity against Escherichia coli J53 transconjugated with Proteus mirabilis pHS10 carrying qnrC gene by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. |
| AID400380 | Antibacterial activity against Proteus mirabilis after at 200 ug/100uL 24 hrs by agar well diffusion method | 1998 | Journal of natural products, Feb, Volume: 61, Issue:2 | Antibacterial steroidal alkaloids from Sarcococca saligna. |
| AID547765 | Antimicrobial activity against Escherichia coli DH10B harboring plasmid pBR322-catI carrying beta-lactamase KPC-2 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID554991 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 67 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID557720 | Antimicrobial activity in Fusobacterium mortiferum by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID495333 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with Ile449Val, Ala502Thr, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID478496 | Antibacterial activity against Staphylococcus epidermidis at 2 mg/ml after 24 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5 | Synthesis and antimicrobial of new anthraquinone derivatives incorporating pyrazole moiety. |
| AID736393 | Antibacterial activity against Acinetobacter calcoaceticus DSM 586 by paper disk diffusion method | 2013 | Journal of natural products, Jan-25, Volume: 76, Issue:1 | Antibacterial and antiplasmodial constituents of Beilschmiedia cryptocaryoides. |
| AID360054 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as lactoyl tri-aspartate-peptide level | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID544278 | Antimicrobial activity against Enterococcus faecalis NKH8 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1314113 | Inhibition of fluorescein-labeled probe binding to Bacillus anthracis N-terminal His-tagged DHPS incubated for 1 hr by fluorescence polarization assay | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16 | Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents. |
| AID1286513 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolate after 20 to 24 hrs in presence of 50% heat inactivated bovine serum | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID522390 | Activity of Escherichia coli K-12 Beta-lactamase AmpC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Genetic and biochemical characterization of TRU-1, the endogenous class C beta-lactamase from Aeromonas enteropelogenes. |
| AID1491151 | Antibacterial activity against Bacillus subtilis BS01 by CLSI method | 2017 | Journal of natural products, 05-26, Volume: 80, Issue:5 | Antimicrobial Spirotetronate Metabolites from Marine-Derived Micromonospora harpali SCSIO GJ089. |
| AID524970 | Antibacterial activity against vancomycin- and teichoplanin-nonsusceptible Enterococcus faecium clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Comparative surveillance study of telavancin activity against recently collected gram-positive clinical isolates from across the United States. |
| AID573342 | Antibacterial activity against ceftazidime-susceptible Citrobacter freundii assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID735974 | Antimicrobial activity against Fusarium oxysporum after 48 hrs by microdilution susceptibility test | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Synthesis and antimicrobial activity of some new benzo and naphthonitrile derivatives. |
| AID66418 | In vitro inhibitory activity against enterococci EryRc (13);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID529590 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-1 assessed as bacterial density at 1024 ug/ml after 18 hrs | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID547801 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237W mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID529581 | Ratio of Kcat to Km for Janthinobacterium lividum THIN-B | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora. |
| AID555235 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 20 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID565679 | Antimicrobial activity against beta-lactamase negative ampicillin-susceptible Haemophilus influenzae harboring fst1 mutant gene assessed as susceptible isolates by broth microdilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID1648089 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as reduction in microbial growth after 24 hrs by two-fold serial dilution method | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Absolute Configuration and Antibiotic Activity of Piceamycin. |
| AID655619 | Antibacterial activity against Escherichia coli ATCC 35218 at 20 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID572049 | Antibacterial activity against Clostridium sp. by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID671471 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33592 after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Aug-01, Volume: 20, Issue:15 | Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. |
| AID360073 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as tetra -aspartate-penta-aspartate multimer containing D-Ala4 to D-Asp-L-Lys3 cross links at 128 ug/ml by mass spectrometry | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID534967 | Antimicrobial activity against Prevotella loescheii by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID389386 | Antibacterial activity against Micrococcus luteus IFC12708 | 2008 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 18, Issue:20 | Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp. |
| AID562473 | Antimicrobial activity against rifampicin-resistant Escherichia coli A15 transconjugant expressing beta-lactamase KPC-2/TEM-1 by Etest | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland. |
| AID546939 | Antibacterial activity against Salmonella enterica serovar Newport by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID543809 | Bactericidal activity against Escherichia coli ATCC 25922 assessed as eradication of pre-formed biofilm at 50 times MIC after 24 hrs by serial dilution | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID495551 | Antimicrobial activity against Haemophilus influenzae isolate by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID548944 | Antimicrobial activity against Staphylococcus epidermidis ATCC 14990 after18 to 20 hrs by broth dilution method | 2010 | European journal of medicinal chemistry, Dec, Volume: 45, Issue:12 | Synthesis and antimicrobial evaluation of some fused heterocyclic [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives. |
| AID1887296 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as inhibition of bacterial growth incubated for 24 hrs by optical density based analysis | 2022 | Journal of natural products, 09-23, Volume: 85, Issue:9 | Total Syntheses and Antibacterial Evaluations of Neocyclomorusin and Related Flavones. |
| AID540967 | Activity of Klebsiella pneumoniae HP205 cephalosporinase CMY-36 by spectrophotometry | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids. |
| AID562926 | Antimicrobial activity against Clostridium difficile CD196 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID548025 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237H mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID374022 | Activity of Serratia fonticola UTAD54 SFC1 beta lactamase expressed in Escherichia coli BL21(DE3) by SDS-PAGE | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase. |
| AID285510 | Antibacterial activity against Acinetobacter baumannii after 24 hrs by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens. |
| AID429082 | Antibacterial activity against penicillin-intermediate resistant Neisseria meningitidis clinical isolates harbouring altered penA gene after 24 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Combined real-time PCR and pyrosequencing strategy for objective, sensitive, specific, and high-throughput identification of reduced susceptibility to penicillins in Neisseria meningitidis. |
| AID442421 | Antimicrobial activity against Enterobacter cloacae at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1164941 | Antimicrobial activity against Enterococcus faecalis ATCC 33186 by microbroth dilution method | 2014 | Journal of medicinal chemistry, Oct-23, Volume: 57, Issue:20 | Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives. |
| AID1474808 | Antibacterial activity against Staphylococcus aureus NBRC 100910 after overnight incubation by microdilution method | 2017 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 27, Issue:11 | Syntheses of benzophenone-xanthone hybrid polyketides and their antibacterial activities. |
| AID85791 | In vitro inhibitory activity against Haemophilus AmpS (43) | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID251623 | inhibition of Bacillus subtilis was measured by zone diameter | 2004 | Bioorganic & medicinal chemistry letters, Dec-06, Volume: 14, Issue:23 | Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: a structure-activity evaluation study. |
| AID1908124 | Antibacterial activity against vancomycin resistant Enterococcus faecium ATCC 700221 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID534953 | Antimicrobial activity against Porphyromonas asaccharolyticus by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID556589 | Bactericidal activity against Escherichia coli K-12 BW25113 after 18 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID429369 | Antibacterial activity against Escherichia coli after 24 hrs by liquid dilution method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents. |
| AID245281 | Minimum inhibitory concentration required for antifungal activity against Aspergillus niger ATCC 16404; Not tested | 2004 | Bioorganic & medicinal chemistry letters, Aug-16, Volume: 14, Issue:16 | Synthesis and QSAR studies of pyrimido[4,5-d]pyrimidine-2,5-dione derivatives as potential antimicrobial agents. |
| AID632564 | Antifungal activity against Aspergillus niger at 200 ug/mL after 48 hrs by agar cup diffusion assay | 2011 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 21, Issue:24 | A new antifungal briarane diterpenoid from the gorgonian Junceella juncea Pallas. |
| AID529612 | Antibacterial activity against Beta-lactamase negative Haemophilus influenzae isolate after 20 to 24 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID585429 | Antimicrobial activity against Escherichia coli C600 ST2-T transconjugant harboring oqxAB, qnrB6 and aac(6')-Ib-cr genes by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1388188 | Antibacterial activity against Bacillus subtilis MTCC 10619 incubated for 24 hrs by serial dilution method | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18 | Synthesis, antimicrobial activity, structure-activity relationship and cytotoxic studies of a new series of functionalized (Z)-3-(2-oxo-2-substituted ethylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ones. |
| AID442400 | Antimicrobial activity against Bacillus cereus at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1104314 | Antibacterial activity against Micrococcus flavus ATCC 10240 at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID333993 | Antibacterial activity against Shigella flexneri at 200 ug/100 uL after 24 hrs by tube broth dilution method | 1997 | Journal of natural products, Oct, Volume: 60, Issue:10 | New steroidal alkaloids from Buxus longifolia. |
| AID731203 | Antibacterial activity against Escherichia coli MTCC 443 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles. |
| AID436778 | Antibacterial activity against Proteus mirabilis NCT 289 at 25 ug/mL after 24 hrs by agar diffusion assay | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10 | Synthesis, characterization and in vitro antimicrobial activity of novel 2-thioxo-4-thiazolidinones and 4,4'-bis(2-thioxo-4-thiazolidinone-3-yl)diphenylsulfones. |
| AID565617 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.12 ug/ml (Rvb =798.3 +/- 37.09 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID447435 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by microtitration method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and antibacterial activity of 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-pyrazol-4-yl]-5-(substituted-phenyl)-[1,3,4]oxadiazoles. |
| AID542742 | Antimicrobial activity against Citrobacter freundii D26 expressing qnrB6 and CTX-M-9G genes by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID369630 | Antimicrobial activity against beta-lactamase positive ampicillin-resistant Haemophilus influenzae by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Can the Etest correctly determine the MICs of beta-lactam and cephalosporin antibiotics for beta-lactamase-negative ampicillin-resistant Haemophilus influenzae? |
| AID512149 | Antibacterial activity against Staphylococcus aureus MTCC 1144 at 128 mg/ml after 16 hrs by disk diffusion test | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antiviral and antibacterial agents. |
| AID1194191 | Antimicrobial activity against Staphylococcus aureus ATCC 27154 after 24 hrs by two fold serial microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 25, Issue:8 | Studies on antimicrobial effects of four ligands and their transition metal complexes with 8-mercaptoquinoline and pyridine terminal groups. |
| AID1326386 | Antibacterial activity against Bacillus subtilis P10B derived after 10 passage in presence of JBIR-100 after 16 to 18 hrs by microbroth dilution assay | 2016 | Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24 | Biological characterization of the hygrobafilomycin antibiotic JBIR-100 and bioinformatic insights into the hygrolide family of natural products. |
| AID548797 | Antimicrobial activity against Vancomycin-susceptible Enterococcus faecalis assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID519125 | Antibacterial activity against Proteus mirabilis M 42 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID582924 | Ratio of Kcat to Km for Escherichia coli BL21(DE3) VIM-2 W87A mutant beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1202848 | Antimicrobial activity against Pseudomonas aeruginosa at 10 ug/disc by disc diffusion assay | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Puupehenol, a potent antioxidant antimicrobial meroterpenoid from a Hawaiian deep-water Dactylospongia sp. sponge. |
| AID1596672 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID533384 | Antimicrobial activity against Bacteroides nordii assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID528721 | Antibacterial activity against vancomycin resistant Enterococcus faecalis VanA clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID1314116 | Antibacterial activity against Escherichia coli K-12 in M9 minimal media in presence of folate precursor PABA by turbidometric method | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16 | Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents. |
| AID562381 | Antimicrobial activity against Enterococcus faecium expressing VanA gene clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID743896 | Antibacterial activity against Escherichia coli at 5 mg/mL after 24 hrs | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of fused [1,3,4]thiadiazoles. |
| AID584769 | Antimicrobial activity against Acinetobacter lwoffii isolate H expressing beta-lactamase OXA-58 isolated from tracheal secretion of patient in presence of Sulbactam by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID585862 | Antimicrobial activity against Pseudomonas aeruginosa isolate 11 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID522394 | Ratio of Kcat Km for Escherichia coli K-12 Beta-lactamase AmpC | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Genetic and biochemical characterization of TRU-1, the endogenous class C beta-lactamase from Aeromonas enteropelogenes. |
| AID278245 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-4 gyrA+ with ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID582905 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87V mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID584468 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus vitulinus SVMP04 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID1104309 | Antibacterial activity against Proteus mirabilis at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID1167299 | Antibacterial activity against Clostridium perfringens in tryptic soy broth after 24 hrs | 2014 | Bioorganic & medicinal chemistry, Nov-01, Volume: 22, Issue:21 | Neuraminidase inhibitory activities of quaternary isoquinoline alkaloids from Corydalis turtschaninovii rhizome. |
| AID448148 | Antimicrobial activity against Escherichia coli ATCC 25922 at 10 ug after 18 hrs by well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis of some new 1,2,4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities. |
| AID508593 | Antibacterial activity against ciprofloxacin-susceptibility revert strain of Salmonella enteritidis 104 harboring gyrA D87Y/S83F mutant, parC D79N mutant, soxR E16G/R20H mutant and soxS E52K mutant gene after 20 passages by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Fitness costs and stability of a high-level ciprofloxacin resistance phenotype in Salmonella enterica serotype enteritidis: reduced infectivity associated with decreased expression of Salmonella pathogenicity island 1 genes. |
| AID1825297 | Antibacterial activity against Mycobacterium smegmatis ATCC607 assessed as bacterial growth inhibition | |||
| AID1143590 | Antibacterial activity against Klebsiella pneumoniae assessed as diameter of growth inhibition zone after 24 hrs by two fold serial dilution method | 2014 | European journal of medicinal chemistry, Jun-23, Volume: 81 | Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-arylethanones: antibacterial, DNA photocleavage, and anticancer activities. |
| AID1551811 | Antibacterial activity against methicillin-resistant Staphylococcus aureus incubated for 18 hrs post 30 mins pre-diffusion by disk diffusion method | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID1328338 | Antibacterial activity against Serratia marcescens ATCC 25419 assessed as zone of inhibition at 100 ug/disk measured after 24 hrs by agar disk-diffusion method | 2016 | Journal of natural products, 09-23, Volume: 79, Issue:9 | Halogenated Sesquiterpenoids from the Red Alga Laurencia tristicha Collected in Taiwan. |
| AID583082 | Ratio of Kcat to Km for Escherichia coli BL21(DE3) wild-type VIM-2 beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1265697 | Toxicity in Paracoccus sp. 4M6 assessed as effect on viability at 100 uM after 6 hrs by resazurin-staining assay relative to control | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Click-based synthesis of bromotyrosine alkaloid analogs as potential anti-biofilm leads for SAR studies. |
| AID1887299 | Antibacterial activity against Bacillus subtilis ATCC 11774 assessed as inhibition of bacterial growth incubated for 24 hrs by optical density based analysis | 2022 | Journal of natural products, 09-23, Volume: 85, Issue:9 | Total Syntheses and Antibacterial Evaluations of Neocyclomorusin and Related Flavones. |
| AID544273 | Antimicrobial activity against Enterococcus faecalis NKH3 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID545424 | Antimicrobial activity against Citrobacter freundii obtained from patient with complicated intra-abdominal infection assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID520387 | Ratio of Kcat to Km for Pseudomonas aeruginosa M5109 metallo-beta-lactamase VIM-11 | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain. |
| AID583093 | Antimicrobial activity against Escherichia coli XL1-Blue harboring pBC-SK plasmid by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1372808 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 9027 by two-fold serial dilution assay | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2 | An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold. |
| AID523272 | Antimicrobial activity against Escherichia coli HN1157/pHSG576oxa7 assessed as minimal drug concentration | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Kinetic parameters of efflux of penicillins by the multidrug efflux transporter AcrAB-TolC of Escherichia coli. |
| AID547797 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237F mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID546976 | Antibacterial activity against Aeromonas veronii assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID287697 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by broth microdilution method | 2007 | Bioorganic & medicinal chemistry, Mar-15, Volume: 15, Issue:6 | Synthesis and structure-antibacterial activity relationship investigation of isomeric 2,3,5-substituted perhydropyrrolo[3,4-d]isoxazole-4,6-diones. |
| AID530216 | Antimicrobial activity against Mycobacterium bovis BCG ML1065 carrying transposon IS1096::Km inserted at +96bp of bcg0061 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID529626 | Antibacterial activity against Beta-lactamase negative Haemophilus influenzae harboring fst1 mutant gene assessed as resistant isolates after 20 to 24 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID587732 | Activity of Pseudomonas aeruginosa strain PS 297 metallo-beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) assessed as substrate hydrolysis using 100 uM nitrocefin | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States. |
| AID725075 | Antimicrobial activity against Pseudomonas aeruginosa after 12 to 18 hrs by micro-well dilution method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Synthesis and antibacterial and antifungal evaluation of some chalcone based sulfones and bisulfones. |
| AID508291 | Antimicrobial activity against Enterococcus faecium D63 by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Interaction of ceftobiprole with the low-affinity PBP 5 of Enterococcus faecium. |
| AID1265771 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by two-fold serial dilution method | 2016 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 26, Issue:1 | Discovery of bisindolyl-substituted cycloalkane-anellated indoles as novel class of antibacterial agents against S. aureus and MRSA. |
| AID1286491 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 49775 after 20 to 24 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID625289 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver disease | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID1104322 | Antibacterial activity against clinical isolate Bacillus cereus at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID572261 | Antibacterial activity against Prevotella disiens by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID613616 | Antibacterial activity against 10'8 CFU/mL Candida albicans MTCC 227 by NCCLS M100-S12(M7) broth microdilution method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis and identification of β-aryloxyquinolines and their pyrano[3,2-c]chromene derivatives as a new class of antimicrobial and antituberculosis agents. |
| AID567470 | Antimicrobial activity against gBLNAS Haemophilus influenzae by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | In vitro activity of tebipenem, a new oral carbapenem antibiotic, against beta-lactamase-nonproducing, ampicillin-resistant Haemophilus influenzae. |
| AID1474167 | Liver toxicity in human assessed as induction of drug-induced liver injury by measuring verified drug-induced liver injury concern status | 2016 | Drug discovery today, Apr, Volume: 21, Issue:4 | DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. |
| AID324361 | Activity of Acinetobacter johnsonii SCO1 | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina. |
| AID534388 | Antibacterial activity against Escherichia coli JM109 harboring recombinant pKHM-1 by microdilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate. |
| AID1870142 | Antibacterial activity against wild type Staphylococcus aureus 4904/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID557208 | Antibacterial activity against Beta-lactamase-negative Neisseria meningitidis by Etest method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antibiotic susceptibility and characteristics of Neisseria meningitidis isolates from the African meningitis belt, 2000 to 2006: phenotypic and genotypic perspectives. |
| AID557434 | Antimicrobial activity in Bacteroides stercoris by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1821096 | Antibacterial activity against Salmonella enterica ATCC 14028 assessed as inhibition of bacterial growth incubated for 24 hr by CLSI based broth microdilution method | |||
| AID555468 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 103 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID405313 | Antibacterial activity against Haemophilus influenzae group I isolates with ftsI gene mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID1493683 | Antimicrobial activity against Staphylococcus aureus RCMB 010027 assessed as diameter of zone inhibition at 1 mg/ml after 24 hrs by agar well diffusion assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Quinoline derivatives bearing pyrazole moiety: Synthesis and biological evaluation as possible antibacterial and antifungal agents. |
| AID1585546 | Antibacterial activity against Pseudomonas aeruginosa assessed as zone of inhibition at 1 mg/ml after 32 hrs by agar-well diffusion method | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Benzofuran derivatives and their anti-tubercular, anti-bacterial activities. |
| AID1706150 | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as reduction in bacterial growth incubated for 18 hrs by CLSI based broth microdilution assay | |||
| AID533878 | Antibacterial activity against amoxicillin-resistant Streptococcus pneumoniae isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro activity of ceftaroline against Streptococcus pneumoniae isolates exhibiting resistance to penicillin, amoxicillin, and cefotaxime. |
| AID587242 | Antimicrobial activity against Staphylococcus aureus DSM 799 at 1 ug/ul after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID561515 | Antibacterial activity against Enterococcus faecium by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID278541 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium longum R0175 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID544281 | Antimicrobial activity against Enterococcus faecalis NKH11 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1337801 | Antibacterial activity against Bacillus subtilis NCIM 2079 measured after 12 hrs | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Quinolidene-rhodanine conjugates: Facile synthesis and biological evaluation. |
| AID304970 | Antibacterial activity against Pseudomonas aeruginosa by broth micro-dilution technique | 2007 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1 | New antifungal flavonoid glycoside from Vitex negundo. |
| AID567777 | Antimicrobial activity against Proteus mirabilis ATCC 12453 assessed as >99.9 % reduction in CFU after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID1287091 | Antimicrobial activity against antibiotic resistant Candida albicans clinical isolate 08022821 after 16 hrs by broth dilution method | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis. |
| AID546930 | Antibacterial activity against Salmonella enterica serovar Typhi by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID587981 | Antibacterial activity against Escherichia coli AS226 carrying pBSDD240S mutant after 18 hrs by broth microdilution method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID662085 | Antibacterial activity against Vibrio splendidus after 20 hrs by liquid growth inhibition assay | 2012 | Journal of medicinal chemistry, Mar-08, Volume: 55, Issue:5 | From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity. |
| AID278237 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-2 gyrA+ with ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID557450 | Antimicrobial activity in Prevotella denticola by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID543802 | Bactericidal activity against Escherichia coli ATCC 25922 assessed as eradication of pre-formed biofilm at 1 to 10 times MIC after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID585195 | Antimicrobial activity against Escherichia coli DH5[alpha] transformed with pAC-ges1 plasmid encoding Beta-lactamase GES-2 E104, N170 mutant by Etest method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases. |
| AID551088 | Antibacterial activity against Salmonella Typhimurium at 1000 ug/mL after 72 hrs by agar diffusion assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1 | 3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents. |
| AID1408105 | Antibacterial activity against Bacillus cereus UW 85 after 24 hrs by two-fold serial dilution method | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157 | Design, synthesis, antimicrobial, antiquorum-sensing and antitumor evaluation of new series of pyrazolopyridine derivatives. |
| AID420053 | Antimicrobial activity against Staphylococcus aureus UFPEDA 01 at 10 ug/disk after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID1594846 | Antibiofilm activity against Pseudomonas aeruginosa PAO1 assessed as inhibition of biofilm formation at 0.25 times MIC incubated for 24 hrs by crystal violet staining based ELISA method | 2019 | Journal of natural products, 06-28, Volume: 82, Issue:6 | Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. |
| AID536092 | Antimicrobial activity against Candida albicans IFO 0583 after 48 hrs | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID1697870 | Antimicrobial activity against Escherichia coli ATCC 25922 incubated for 24 hrs by broth microdilution method | |||
| AID558788 | Antimicrobial activity against Citrobacter freundii assessed as percent susceptible isolates by CLSI method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007. |
| AID520989 | Antimicrobial activity against Yersinia pestis CO92 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Novel antimicrobial peptides that exhibit activity against select agents and other drug resistant bacteria. |
| AID735983 | Antimicrobial activity against Bacillus thuringiensis at 1 mg/mL after 24 hrs by agar disc diffusion method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Synthesis and antimicrobial activity of some new benzo and naphthonitrile derivatives. |
| AID1388194 | Antibacterial activity against Streptomyces griseus MTCC 4734 at 100 ug/ml incubated for 12 hrs by agar disc diffusion assay | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18 | Synthesis, antimicrobial activity, structure-activity relationship and cytotoxic studies of a new series of functionalized (Z)-3-(2-oxo-2-substituted ethylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ones. |
| AID494164 | Antibacterial activity against Staphylococcus aureus Smith after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, characterization, in vitro and molecular docking studies of new 2,5-dichloro thienyl substituted thiazole derivatives for antimicrobial properties. |
| AID535221 | Antimicrobial activity against Actinomyces meyeri by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID528532 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B68 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID565015 | Bactericidal activity against methicillin-susceptible coagulase-negative Staphylococcus simulans after 24 hrs by plate counting method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID568827 | Antimicrobial activity against Bacillus subtilis ATCC 6633 at 25 ug/ml by agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis of 4H-chromene, coumarin, 12H-chromeno[2,3-d]pyrimidine derivatives and some of their antimicrobial and cytotoxicity activities. |
| AID533370 | Antimicrobial activity against Bacteroides vulgatus by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID533408 | Antimicrobial activity against Clostridium tertium assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID558319 | Antibacterial activity against Campylobacter coli by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID360051 | Inhibition of Enterococcus faecium LD-transpeptidase assessed by formation of Ac2-L-Lys-D-[14C]Ala from Ac2-L-Lys-D-Ala and D-[14C]Ala | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID392753 | Antibacterial activity against Escherichia coli 25922 after 18 to 24 hrs by tube dilution method | 2009 | Bioorganic & medicinal chemistry, Feb-15, Volume: 17, Issue:4 | Synthesis and antimicrobial evaluation of some new substituted purine derivatives. |
| AID562380 | Antimicrobial activity against Enterococcus faecium expressing VanB gene clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID583095 | Antimicrobial activity against Escherichia coli XL1-Blue harboring pLBII-VIM-2 plasmid expressing VIM-2 W87A mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1411630 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by microdilution method | |||
| AID293858 | Antibacterial activity against methicillin-resistant Staphylococcus aureus CMAH 0430 after 24 hrs by two fold dilution method | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6 | Synthesis of pseudopeptides based L-tryptophan as a potential antimicrobial agent. |
| AID161931 | In vitro inhibitory activity against Pneumococci EryRc (34);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID1614662 | Bactericidal activity against persistent form of Escherichia coli assessed as reduction in colony forming units by fluorescent based time-kill assay | 2019 | Journal of medicinal chemistry, 02-28, Volume: 62, Issue:4 | Deciphering the Role of Intramolecular Networking in Cholic Acid-Peptide Conjugates on the Lipopolysaccharide Surface in Combating Gram-Negative Bacterial Infections. |
| AID644177 | Antibacterial activity against Enterobacter cloacae human isolate treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID509711 | Antibacterial activity against Salmonella typhi at 50 ug/ml after 24 hrs by agar cup diffusion method | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of some 3-substituted amino-4,5-tetramethylene thieno[2,3-d][ 1,2,3]-triazin-4(3H)-ones as potential antimicrobial agents. |
| AID600674 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID387669 | Antibacterial activity against Shigella dysenteriae AE 14396 after 48 hrs by disc diffusion method | 2008 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 18, Issue:19 | Design and synthesis of 3-pyrazolyl-thiophene, thieno[2,3-d]pyrimidines as new bioactive and pharmacological activities. |
| AID519121 | Antibacterial activity against Proteus mirabilis M 17 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID565662 | Antimicrobial activity against beta-lactamase negative ampicillin-resistant Haemophilus influenzae assessed as susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID572041 | Antibacterial activity against Clostridium orbiscindens by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID534772 | Antimicrobial activity against Acinetobacter baumannii-calcoaceticus obtained from war-wounded patient assessed as susceptible isolates in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | In vitro activity of the aminoglycoside antibiotic arbekacin against Acinetobacter baumannii-calcoaceticus isolated from war-wounded patients at Walter Reed Army Medical Center. |
| AID540836 | Antimicrobial activity against ciprofloxacin-resistant Salmonella enterica serovar enteritidis isolate 5408-cip harboring gyrA D87Y, gyrB E466D, parE V461G mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID405323 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae group IIb isolates with acrR aminoacid substitution mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID1877437 | Antibacterial activity against Staphylococcus aureus | 2022 | Bioorganic & medicinal chemistry letters, 01-01, Volume: 55 | New bis- and tetrakis-1,2,3-triazole derivatives: Synthesis, DNA cleavage, molecular docking, antimicrobial, antioxidant activity and acid dissociation constants. |
| AID324302 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoR mutant assessed as cell count in log phase at 100 ug/ml after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID324988 | Antibacterial activity against Haemophilus influenzae MSC06663 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID467964 | Antimicrobial activity against Escherichia coli ATCC 11775 after 18 to 24 hrs by liquid broth method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. |
| AID585451 | Antimicrobial activity against ampD, ampDh2, ampDh3 and ampGh1 deficient Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1585654 | Antibacterial activity against methicillin-resistant Staphylococcus haemolyticus after overnight incubation by micro broth dilution analysis | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug resistance of bacterial infections. |
| AID562355 | Antimicrobial activity against fusidic acid-, rifampin-resistant Enterococcus faecium TX1330RF by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Cotransfer of antibiotic resistance genes and a hylEfm-containing virulence plasmid in Enterococcus faecium. |
| AID625291 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver function tests abnormal | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID436464 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 20 hrs by two fold dilution method | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10 | Synthesis, physicochemical properties and antimicrobial activity of some new benzimidazole derivatives. |
| AID530513 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype IV isolate 3454-03 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID387668 | Antibacterial activity against Bacillus cereus BTCC19 after 48 hrs by disc diffusion method | 2008 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 18, Issue:19 | Design and synthesis of 3-pyrazolyl-thiophene, thieno[2,3-d]pyrimidines as new bioactive and pharmacological activities. |
| AID269644 | Antibacterial activity against Salmonella enteritidis ATCC 13076 | 2006 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 16, Issue:16 | Lactones from a brown alga endophytic fungus (No. ZZF36) from the South China Sea and their antimicrobial activities. |
| AID1193885 | Antimicrobial activity against Staphylococcus aureus MTCC 3160 after 24 hrs by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Rapid 'one-pot' synthesis of a novel benzimidazole-5-carboxylate and its hydrazone derivatives as potential anti-inflammatory and antimicrobial agents. |
| AID520779 | Antibacterial activity against Escherichia coli EC600 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. |
| AID249987 | Minimum inhibitory concentration against Staphylococcus aureus | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Studies on synthesis and evaluation of quantitative structure-activity relationship of 5-[(3'-chloro-4',4'-disubstituted-2-oxoazetidinyl)(N-nitro)amino]-6-hydroxy-3-alkyl/aryl[1,3]azaphospholo[1,5-a]pyridin-1-yl-phosphorus dichlorides. |
| AID540211 | Fraction unbound in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID374026 | Ratio of Kcat to Km for Klebsiella pneumoniae KPC-1 beta lactamase expressed in Escherichia coli DH5alpha by SDS-PAGE | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase. |
| AID362537 | Antibacterial activity against Pseudomonas pallida assessed as zone of inhibition at 0.25 mg/mL by agar well diffusion method | 2008 | Journal of natural products, Aug, Volume: 71, Issue:8 | Bioactive 5alpha-pregnane-type steroidal alkaloids from Sarcococca hookeriana. |
| AID587727 | Antimicrobial activity against Escherichia coli DH5alpha carrying Pseudomonas aeruginosa strain PS 297 IMP-18-pLBII after 18 hrs by microdilution broth method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States. |
| AID334245 | Antimicrobial activity against Pseudomonas aeruginosa NCIMB 10421 after 24 hrs by microdilution technique | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4 | Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline. |
| AID568677 | Antimicrobial activity against Edwardsiella tarda assessed as growth inhibition at 10 ug/ml by agar dilution method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and structure-activity relationship of 2-thiopyrimidine-4-one analogs as antimicrobial and anticancer agents. |
| AID1329752 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 after 24 hrs by broth microdilution method | |||
| AID313665 | Antibacterial activity against Staphylococcus aureus ATCC 6538p after 24 hrs | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1 | Antimicrobial activities of the bromophenols from the red alga Odonthalia corymbifera and some synthetic derivatives. |
| AID547767 | Antimicrobial activity against Escherichia coli DH10B harboring plasmid pBR322-catI carrying beta-lactamase KPC-2 by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID543801 | Bactericidal activity against Klebsiella pneumoniae VT 1367 assessed as eradication of pre-formed biofilm at 1 to 10 times MIC after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID557712 | Antimicrobial activity in Fusobacterium nucleatum by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1246295 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus HEMSA incubated for 20 hrs in presence of sulbactam by serial dilution broth microplate method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | Imidazolidine-4-one derivatives in the search for novel chemosensitizers of Staphylococcus aureus MRSA: synthesis, biological evaluation and molecular modeling studies. |
| AID1262358 | Antibacterial activity against clinical isolates Escherichia coli after 24 hrs by agar diffusion assay | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | PPL catalyzed four-component PASE synthesis of 5-monosubstituted barbiturates: Structure and pharmacological properties. |
| AID278265 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS18 gyrA+ with GyrA S38F mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID543415 | Antimicrobial activity against rifampicin-resistant Escherichia coli X1037 transconjugant by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime. |
| AID1762809 | Antibacterial activity against Carbapenem-resistant Pseudomonas aeruginosa assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | 2021 | Bioorganic & medicinal chemistry, 05-15, Volume: 38 | Dipyridyl-substituted thiosemicarbazone as a potent broad-spectrum inhibitor of metallo-β-lactamases. |
| AID448153 | Antimicrobial activity against Bacillus cereus 702 Roma at 10 ug after 18 hrs by well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis of some new 1,2,4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities. |
| AID775558 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus 630 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21 | New derivatives of salicylamides: Preparation and antimicrobial activity against various bacterial species. |
| AID1916814 | Antibacterial activity against Pseudomonas aeruginosa NCIM 2036 assessed as bacterial growth inhibition incubated for 8 hrs by absorbance based assay | 2022 | European journal of medicinal chemistry, Aug-05, Volume: 238 | Recent contribution of medicinally active 2-aminothiophenes: A privileged scaffold for drug discovery. |
| AID1159100 | Antimicrobial activity against Proteus vulgaris ATCC 33420 assessed as zone of inhibition at 10 mg by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID278264 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS18 with GyrA S38F mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID554987 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 52 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID162883 | Minimum inhibitory concentration of Ampicillin required for growth inhibition of Beta lactamase producing bacteria Proteus mirabilis (121K) | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8 | Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives. |
| AID1176779 | Antimicrobial activity against Candida albicans ATCC 1023 after 24 hrs by broth microdilution method | 2015 | Journal of natural products, Jan-23, Volume: 78, Issue:1 | Structure and antimicrobial activity of phloroglucinol derivatives from Achyrocline satureioides. |
| AID1697872 | Antimicrobial activity against Staphylococcus aureus ATCC 29737 incubated for 24 hrs by broth microdilution method | |||
| AID1695928 | Antibacterial activity against Micrococcus luteus IFC 12708 incubated for 24 hrs by broth dilution method | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID770395 | Antibacterial activity against Escherichia coli BL21(DE3) assessed as growth inhibition at 37 degC after 24 hrs by two-fold dilution method | 2013 | Journal of medicinal chemistry, Sep-26, Volume: 56, Issue:18 | Screening and evaluation of small organic molecules as ClpB inhibitors and potential antimicrobials. |
| AID655617 | Antibacterial activity against Escherichia coli ATCC 35218 at 80 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID1075975 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 72 hrs by broth micro-dilution method | 2014 | European journal of medicinal chemistry, Mar-21, Volume: 75 | Toward new classes of potent antibiotics: synthesis and antimicrobial activity of novel metallosaldach-imidazolium salts. |
| AID1399263 | Antimicrobial activity against tolC deficient Escherichia coli JW5503-1 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID525545 | Antimicrobial activity against Haemophilus influenzae Rd KW20 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Haemophilus influenzae clinical isolates with plasmid pB1000 bearing blaROB-1: fitness cost and interspecies dissemination. |
| AID666964 | Antifungal activity against Aspergillus fumigatus MTCC 3008 by broth microdilution method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | New N-arylamino biquinoline derivatives: synthesis, antimicrobial, antituberculosis, and antimalarial evaluation. |
| AID1384552 | Antibacterial activity against Staphylococcus aureus after 16 to 18 hrs | 2018 | European journal of medicinal chemistry, Apr-25, Volume: 150 | Structure-based design of bacterial transglycosylase inhibitors incorporating biphenyl, amine linker and 2-alkoxy-3-phosphorylpropanoate moieties. |
| AID568631 | Antibacterial activity against Streptococcus pneumoniae CGMCC 1.1692 after 24 hrs | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1 | N-hydroxypyridones, phenylhydrazones, and a quinazolinone from Isaria farinosa. |
| AID1235342 | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as zone of inhibition at 2862 uM incubated overnight at 37 degC | 2015 | Journal of natural products, Jul-24, Volume: 78, Issue:7 | Phytochemical Investigation of the Constituents Derived from the Australian Plant Macropidia fuliginosa. |
| AID1185315 | Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis and 3D-QSAR studies of new diphenylamine containing 1,2,4-triazoles as potential antitubercular agents. |
| AID373668 | Antibacterial activity against Enterococcus faecalis ATCC 29212 at 10 ug/disk after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID557696 | Antimicrobial activity in Prevotella salivae by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID279563 | Antimicrobial activity against Haemophilus influenzae BLNAR strains | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Diversity of ampicillin resistance genes and antimicrobial susceptibility patterns in Haemophilus influenzae strains isolated in Korea. |
| AID1126669 | Antibacterial activity against Escherichia coli MTCC 443 assessed as growth inhibition after 24 to 48 hrs by broth microdilution method | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Synthesis, characterization and pharmacological screening of some novel 5-imidazopyrazole incorporated polyhydroquinoline derivatives. |
| AID373468 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 at 10 ug/disk after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID625279 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID555237 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 21 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID495344 | Antimicrobial activity against Beta-lactamase-positive, ampicillin-cluvulanate-resistant Haemophilus influenzae with Asp350Asn, Met377Ile, Gly490Glu, Ala502Val, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID519631 | Activity of Brachyspira pilosicoli beta-lactamase OXA-63 expressed in Escherichia coli BL21 (DE3) assessed as compound hydrolysis by spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442. |
| AID324211 | Antibacterial activity against Escherichia coli K12 containing PhoU mutant assessed as cell count in stationary phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID405821 | Antimicrobial activity against Acinetobacter baumannii 695 isolate harboring bla IMP-1 carrying integron In86 containing aminoglycoside resistance gene aac(6')-3 | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital. |
| AID559576 | Antimicrobial activity against Waddlia chondrophila ATCC VR-1470 infected in Acanthamoeba castellanii amoeba cells | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic susceptibility of Waddlia chondrophila in Acanthamoeba castellanii amoebae. |
| AID563974 | Activity of Klebsiella pneumoniae 05-560 beta-lactamase IMP1 by spectrophotometry | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. |
| AID318663 | Antibacterial activity against Clostridium perfringens GAI 5526 by broth microdilution method | 2008 | Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7 | Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens. |
| AID207857 | The compound was tested for minimal inhibitory concentration against Resistant Staphylococcus aureus | 2002 | Bioorganic & medicinal chemistry letters, Sep-02, Volume: 12, Issue:17 | The activity of p-methoxybenzylisothiocyanate against Neisseria gonorrhoeae, Haemophilus ducreyi, and other microorganisms. |
| AID539557 | Antimicrobial activity against Bacillus subtilis ATCC 6633 | 2010 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 20, Issue:23 | Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase. |
| AID520386 | Activity at Pseudomonas aeruginosa COL-1 metallo-beta lactamase VIM-2 by spectrometry | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain. |
| AID573371 | Antibacterial activity against ceftazidime-susceptible Serratia marcescens assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID585436 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID456087 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID613610 | Antibacterial activity against 10'8 CFU/mL Clostridium tetani MTCC 449 by NCCLS M100-S12(M7) broth microdilution method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis and identification of β-aryloxyquinolines and their pyrano[3,2-c]chromene derivatives as a new class of antimicrobial and antituberculosis agents. |
| AID1617680 | Antibacterial activity against methicillin-resistant Staphylococcus aureus shhs-A1 by CLSI based two-fold serial dilution method | |||
| AID562227 | Antimicrobial activity against Desulfovibrio desulfuricans Essex 6 in presence of Sulbactam by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID555269 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 128 by Etest method in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID555463 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 67 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID562587 | Antimicrobial activity against Enterococcus faecium expressing VanB gene clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID567460 | Antimicrobial activity against Salmonella enterica serovar Typhi isolate 080048Ty transconjugant harboring bla CTX-M-15 gene by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Plasmid-mediated resistance to cephalosporins in Salmonella enterica serovar Typhi. |
| AID442431 | Antimicrobial activity against Listeria monocytogenes after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID324978 | Antibacterial activity against Haemophilus influenzae MSC01400 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID1076001 | Antibacterial activity against Pseudomonas aeruginosa NCIM 2036 by standard agar method | 2014 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 24, Issue:6 | Synthesis, antileishmanial activity and docking study of N'-substitutedbenzylidene-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetohydrazides. |
| AID320389 | Antimicrobial activity against Escherichia coli NCIM2574 by broth microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 18, Issue:6 | Synthesis and antimicrobial activity of beta-lactam-bile acid conjugates linked via triazole. |
| AID395731 | Antimicrobial activity against imipenem-resistant invasive nontypeable Haemophilus influenzae isolate 184 by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | First characterization of heterogeneous resistance to imipenem in invasive nontypeable Haemophilus influenzae isolates. |
| AID1504233 | Antibacterial activity against Enterococcus faecalis ATCC 19433 after 24 hrs by two fold serial dilution method | 2017 | Journal of natural products, 11-22, Volume: 80, Issue:11 | Nicrophorusamides A and B, Antibacterial Chlorinated Cyclic Peptides from a Gut Bacterium of the Carrion Beetle Nicrophorus concolor. |
| AID278230 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21 acrAB::Kan | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1104316 | Antibacterial activity against Listeria monocytogenes NCTC 7973 at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID389385 | Antibacterial activity against Bacillus subtilis ATCC 6633 | 2008 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 18, Issue:20 | Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp. |
| AID1411625 | Bactericidal activity against Listeria monocytogenes NCTC 7973 incubated for 24 hrs followed by serial sub-cultivation and measured after 24 hrs by microdilution method | |||
| AID562588 | Antimicrobial activity against Enterococcus faecium expressing VanA gene clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID585843 | Antimicrobial activity against Pseudomonas aeruginosa isolate 2 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1368639 | Anti-biofilm activity against Pseudoalteromonas ulvae TC14 assessed as inhibition of bacterial adhesion incubated for 15 hrs at 20 degC by Syto 61 dye based fluorimetric assay | 2018 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 28, Issue:2 | Towards smart biocide-free anti-biofilm strategies: Click-based synthesis of cinnamide analogues as anti-biofilm compounds against marine bacteria. |
| AID275132 | Antibacterial activity against Staphylococcus aureus IAM1011 | 2007 | Journal of natural products, Jan, Volume: 70, Issue:1 | Antimicrobial arylcoumarins from Asphodelus microcarpus. |
| AID425604 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM615 in mouse J774A1 cells isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as intracellular killing of bacteria at 10% compound Cmax a | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID548022 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237E mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID534396 | Ratio of Kcat to Km for Escherichia coli JM109 harboring recombinant pKHM-1 Beta-lactamase KHM-1 assessed as compound hydrolysis by UV-visible spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate. |
| AID400385 | Antibacterial activity against Shigella boydii at 200 ug/100uL after 24 hrs by agar well diffusion method | 1998 | Journal of natural products, Feb, Volume: 61, Issue:2 | Antibacterial steroidal alkaloids from Sarcococca saligna. |
| AID1114117 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 assessed as growth inhibition by broth microdilution method | 2013 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, May, Volume: 22, Issue:5 | Microbiologically active Mannich bases derived from 1,2,4-triazoles. The effect of C-5 substituent on antibacterial activity. |
| AID1264895 | Antimicrobial activity against Escherichia coli ATCC 11775 for 17 to 48 hrs by MTT assay | 2015 | Journal of natural products, Nov-25, Volume: 78, Issue:11 | Identification of Elaiophylin Skeletal Variants from the Indonesian Streptomyces sp. ICBB 9297. |
| AID509326 | Antibacterial activity against ampicillin-resistant Pseudomonas putida MTCC 1072 at 64 mg/ml after 16 hrs by disk diffusion test | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antiviral and antibacterial agents. |
| AID1774180 | Antibacterial activity against Escherichia coli BW25113 assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID519008 | Activity of Beta-lactamase TEM-149 expressed in Escherichia coli HB101 | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | E240V substitution increases catalytic efficiency toward ceftazidime in a new natural TEM-type extended-spectrum beta-lactamase, TEM-149, from Enterobacter aerogenes and Serratia marcescens clinical isolates. |
| AID533205 | Antimicrobial activity against Haemophilus influenzae clinical isolates assessed as susceptible isolates by PK/PD technique | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Antimicrobial resistance among respiratory pathogens in Spain: latest data and changes over 11 years (1996-1997 to 2006-2007). |
| AID567765 | Antimicrobial activity against Micrococcus luteus ATCC 10240 after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID740191 | Antibacterial activity against Escherichia coli NCIM 2256 by agar method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Microwave assisted nano (ZnO-TiO2) catalyzed synthesis of some new 4,5,6,7-tetrahydro-6-((5-substituted-1,3,4-oxadiazol-2-yl)methyl)thieno[2,3-c]pyridine as antimicrobial agents. |
| AID1399499 | Antibacterial activity against Enterobacter cloacae after 24 hrs by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID541022 | Activity at Burkholderia cenocepacia 07-34 beta-lactamase PenB1 expressed in Escherichia coli Top10 by UV-spectrophotometry | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Naturally occurring Class A ss-lactamases from the Burkholderia cepacia complex. |
| AID557466 | Antimicrobial activity in Prevotella disiens by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1593644 | Antibacterial activity against Bacillus subtilis NBRC 3134 after 18 hrs by broth microdilution method | 2019 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 29, Issue:11 | Synthesis, antibacterial and cytotoxic evaluation of flavipucine and its derivatives. |
| AID405455 | Antibacterial activity against Escherichia coli 1540 isolate by disk diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Transferable resistance to aminoglycosides by methylation of G1405 in 16S rRNA and to hydrophilic fluoroquinolones by QepA-mediated efflux in Escherichia coli. |
| AID655701 | Antibacterial activity against Escherichia coli ATCC 35218 after 24 hrs by serial broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID70125 | The compound was tested for minimal inhibitory concentration against Escherichia coli | 2002 | Bioorganic & medicinal chemistry letters, Sep-02, Volume: 12, Issue:17 | The activity of p-methoxybenzylisothiocyanate against Neisseria gonorrhoeae, Haemophilus ducreyi, and other microorganisms. |
| AID147029 | The compound was tested for minimal inhibitory concentration against Neisseria gonorrhoeae | 2002 | Bioorganic & medicinal chemistry letters, Sep-02, Volume: 12, Issue:17 | The activity of p-methoxybenzylisothiocyanate against Neisseria gonorrhoeae, Haemophilus ducreyi, and other microorganisms. |
| AID535201 | Antimicrobial activity against Clostridium rectum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID519119 | Antibacterial activity against Proteus mirabilis NP43 after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID640496 | Antibacterial activity against Salmonella Typhimurium ATCC 14028 | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2 | Bioactive lipids from the sponge Spirastrella abata. |
| AID520869 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus saprophyticus isolate TSU33 isolated from genitourinary tracts of acute cystitis patient after 24 hrs at 35 degC by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Methicillin-resistant Staphylococcus saprophyticus isolates carrying staphylococcal cassette chromosome mec have emerged in urogenital tract infections. |
| AID547803 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237W mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID1411622 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by microdilution method | |||
| AID562523 | Antimicrobial activity against vancomycin-resistant Enterococcus faecium C expressing hylEfm gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Cotransfer of antibiotic resistance genes and a hylEfm-containing virulence plasmid in Enterococcus faecium. |
| AID529614 | Antibacterial activity against Beta-lactamase negative Haemophilus influenzae assessed as resistant isolates after 20 to 24 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID1126666 | Antibacterial activity against Streptococcus pneumoniae MTCC 1936 assessed as growth inhibition after 24 to 48 hrs by broth microdilution method | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Synthesis, characterization and pharmacological screening of some novel 5-imidazopyrazole incorporated polyhydroquinoline derivatives. |
| AID557974 | Antimicrobial activity in Clostridium tertium by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID324298 | Antibacterial activity against Escherichia coli K12 containing deletion deltahipA mutant assessed as cell count in log phase at 100 ug/ml after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID543797 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID395732 | Antimicrobial activity against imipenem-susceptible invasive nontypeable Haemophilus influenzae isolate 187 by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | First characterization of heterogeneous resistance to imipenem in invasive nontypeable Haemophilus influenzae isolates. |
| AID489648 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID565615 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.08 ug/ml (Rvb =798.3 +/- 37.09 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID547185 | Antibacterial activity against Vibrio vulnificus by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID548477 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega after 24 hrs by Etest in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID584766 | Antimicrobial activity against Acinetobacter lwoffii isolate E expressing beta-lactamase OXA-164 isolated from tracheal secretion of patient in presence of Sulbactam by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID324991 | Antibacterial activity against Haemophilus influenzae MSC07771 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID551085 | Antibacterial activity against Streptococcus pyogenes at 1000 ug/mL after 72 hrs by agar diffusion assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1 | 3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents. |
| AID1499660 | Antimicrobial activity against Staphylococcus aureus RCMB 010028 after 24 hrs by serial dilution method | 2017 | European journal of medicinal chemistry, Sep-29, Volume: 138 | Design, synthesis and 2D QSAR study of novel pyridine and quinolone hydrazone derivatives as potential antimicrobial and antitubercular agents. |
| AID519641 | Antimicrobial activity against Escherichia coli EPI300 harboring pCC1 carrying beta-lactamase CTX-M-3 gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID504049 | Antimicrobial activity against Staphylococcus aureus MTCC 96 by broth microdilution technique | 2010 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 20, Issue:18 | Synthesis and antimicrobial activity of novel fluorine containing 4-(substituted-2-hydroxybenzoyl)-1H-pyrazoles and pyrazolyl benzo[d]oxazoles. |
| AID555254 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 67 by Etest method in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID758272 | Antibacterial activity against Clostridium tetani MTCC 449 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Design and synthesis of biquinolone-isoniazid hybrids as a new class of antitubercular and antimicrobial agents. |
| AID546956 | Antibacterial activity against Shigella boydii assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID660262 | Ratio of MIC for wild type Escherichia coli TG1 to MIC for acrB-deficient Escherichia coli KAM3 by two-fold serial dilution method | 2012 | European journal of medicinal chemistry, Jun, Volume: 52 | Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics. |
| AID1228012 | Antimicrobial activity against Escherichia coli ATCC 35218 assessed as complete prevention of visible growth after incubation at 37 degC for 18 to 20 hrs | 2015 | Journal of natural products, Apr-24, Volume: 78, Issue:4 | Antibacterial Biphenanthrenes from the Fibrous Roots of Bletilla striata. |
| AID614151 | Antimicrobial activity against Staphylococcus aureus ATCC 6538p | 2011 | Journal of natural products, Aug-26, Volume: 74, Issue:8 | Sesterterpenes from the tropical sponge Coscinoderma sp. |
| AID723713 | Bactericidal activity against Salmonella typhi after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID1359445 | Antibacterial activity against Enterobacter sp. NCIM 5392 after 8 hrs by serial dilution method | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Antibacterial and anti-TB tat-peptidomimetics with improved efficacy and half-life. |
| AID1585675 | Antibiofilm activity against methicillin-resistant Staphylococcus aureus at 2 times MIC after 24 hrs by crystal violet staining-based UV-visible spectrophotometric analysis | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug resistance of bacterial infections. |
| AID513176 | Displacement of [3H]astemizole from free heme crystal at 15 uM after 16 hrs by scintillation counting | 2006 | Nature chemical biology, Aug, Volume: 2, Issue:8 | A clinical drug library screen identifies astemizole as an antimalarial agent. |
| AID1202845 | Antimicrobial activity against Staphylococcus aureus at 10 ug/disc by disc diffusion assay | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Puupehenol, a potent antioxidant antimicrobial meroterpenoid from a Hawaiian deep-water Dactylospongia sp. sponge. |
| AID1491078 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by serial two fold dilution method | 2017 | Journal of natural products, 05-26, Volume: 80, Issue:5 | Manzamine Alkaloids from an Acanthostrongylophora sp. Sponge. |
| AID381880 | Antibacterial activity against Escherichia coli after 24 hrs by broth microdilution method | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | Bioactive alkenylphenols from Piper obliquum. |
| AID633496 | Antifungal activity against Trichophyton mentagrophytes IFO 40996 after 48 to 72 hrs by two fold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial activity of brominated resorcinol dimers. |
| AID562928 | Antimicrobial activity against Clostridium difficile ATCC 43603 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID1596675 | Bactericidal activity against Listeria monocytogenes NCTC 7973 incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID360076 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as tetra-aspartate-tetra-aspartate-penta-aspartate multimer containing D-Ala4 to D-Asp-L-Lys3 cross links at 128 ug/ml by mass spectrometry | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID567767 | Antimicrobial activity against Klebsiella pneumoniae ATCC 13883 after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID514130 | Antibacterial activity against methicillin-resistant Staphylococcus aureus Mu50 assessed as growth inhibition at 1 mg/ml after 16 to 20 hrs in presence of 0.2 mM L-histidine | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays. |
| AID1286493 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 25923 after 20 to 24 hrs in presence of 50% heat inactivated bovine serum | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID1303882 | Antibacterial activity against multidrug resistant Staphylococcus aureus subsp. aureus Seattle 1945 (ATCC 25923) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID1570733 | Antimicrobial activity against Enterococcus faecium AUS0004 at 2 ug/disk incubated for 20 +/- 4 hrs by agar disk diffusion method | 2019 | Bioorganic & medicinal chemistry, 11-01, Volume: 27, Issue:21 | Synthesis and evaluation of 1,3,4-oxadiazole derivatives for development as broad-spectrum antibiotics. |
| AID585196 | Antimicrobial activity against Escherichia coli DH5[alpha] transformed with pAC-ges1 plasmid encoding Beta-lactamase GES-6 K104, S170 mutant by Etest method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases. |
| AID635061 | Antibacterial activity against drug-sensitive Micrococcus luteus ATCC 10240 by broth microdilution method | 2012 | European journal of medicinal chemistry, Jan, Volume: 47, Issue:1 | Studies on the synthesis and antibacterial activity of 3,6-disubstituted 1,2,4-triazolo[3,4-b]1,3,4-thiadiazoles. |
| AID529892 | Antimicrobial activity against Leptospira interrogans isolate 7 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID1104323 | Antibacterial activity against Micrococcus flavus ATCC 10240 at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID324169 | Antibacterial activity against Escherichia coli K12 mutant JHU313 at 25 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID662080 | Antibacterial activity against Pseudomonas aeruginosa after 20 hrs by liquid growth inhibition assay | 2012 | Journal of medicinal chemistry, Mar-08, Volume: 55, Issue:5 | From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity. |
| AID374025 | Activity of Klebsiella pneumoniae KPC-1 beta lactamase expressed in Escherichia coli DH5alpha by SDS-PAGE | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase. |
| AID465612 | Antibacterial activity against Micrococcus luteus IFO 12708 | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Discorhabdins from the Korean marine sponge Sceptrella sp. |
| AID520713 | Antibacterial activity against Escherichia coli TOP10 harboring pOXA-97 | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID1653052 | Antibacterial activity against Shigella flexneri | 2019 | European journal of medicinal chemistry, Feb-15, Volume: 164 | Isatin derivatives and their anti-bacterial activities. |
| AID442425 | Antimicrobial activity against Micrococcus flavus after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID562940 | Effect on fbp69 gene expression in Clostridium difficile CD07-259 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID438297 | Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2X preincubated for 1 hr before addition of substrate (R)-[2-(benzoylamino)propionylsulfanyl]acetic acid | 2009 | Journal of medicinal chemistry, Oct-08, Volume: 52, Issue:19 | Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening. |
| AID535451 | Antimicrobial activity against Lactobacillus plantarum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID1769954 | Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC513045 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID587986 | Antibacterial activity against Escherichia coli AS226 after 18 hrs by broth microdilution method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID324227 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 assessed as cell count in stationary phase at 100 ug/ml after 5 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1126667 | Antibacterial activity against Bacillus subtilis MTCC 441 assessed as growth inhibition after 24 to 48 hrs by broth microdilution method | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Synthesis, characterization and pharmacological screening of some novel 5-imidazopyrazole incorporated polyhydroquinoline derivatives. |
| AID1331879 | Antimycobacterial activity against Mycobacterium smegmatis MC2 155 | 2017 | Bioorganic & medicinal chemistry, 01-01, Volume: 25, Issue:1 | Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. |
| AID1347700 | Binding affinity to Escherichia coli pUC18 DNA assessed as protection against DNase1-mediated cleavage at 500 uM preincubated for 30 mins followed by DNase1 addition measured after 5 mins by 1% agarose gel based UV-transilluminator analysis | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis and bio-evaluation of indole-chalcone based benzopyrans as promising antiligase and antiproliferative agents. |
| AID565678 | Antimicrobial activity against beta-lactamase negative ampicillin-susceptible Haemophilus influenzae harboring fst1 mutant gene assessed as susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID625292 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) combined score | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID740192 | Antibacterial activity against Staphylococcus aureus NCIM 2901 by agar method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Microwave assisted nano (ZnO-TiO2) catalyzed synthesis of some new 4,5,6,7-tetrahydro-6-((5-substituted-1,3,4-oxadiazol-2-yl)methyl)thieno[2,3-c]pyridine as antimicrobial agents. |
| AID269641 | Antibacterial activity against Staphylococcus aureus ATCC 27154 | 2006 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 16, Issue:16 | Lactones from a brown alga endophytic fungus (No. ZZF36) from the South China Sea and their antimicrobial activities. |
| AID360058 | Inhibition of Enterococcus faecium M512 LDtfm transpeptidase activity assessed as tri-aspartate tri multimer containing L-Lys3 to D-Asp-L-Lys3 cross links at 8 ug/ml | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID460803 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii BAA-1605 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID266674 | Antibacterial activity against Streptococcus faecalis | 2006 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 16, Issue:14 | Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives. |
| AID1577954 | Antimicrobial activity against Pseudomonas aeruginosa PA6 under iron-sufficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID1328383 | Antibacterial activity against Rhodococcus fascians after 24 hrs by MTT based microdilution assay | 2016 | Journal of natural products, 09-23, Volume: 79, Issue:9 | Total Synthesis of (±)-Isoperbergins and Correction of the Chemical Structure of Perbergin. |
| AID595277 | Antimicrobial activity against Bacillus subtilis at 1 mg/ml after 24 hrs by agar well diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Applications of 2-arylhydrazononitriles in synthesis: preparation of new indole containing 1,2,3-triazole, pyrazole and pyrazolo[1,5-a]pyrimidine derivatives and evaluation of their antimicrobial activities. |
| AID585629 | Antimicrobial activity against kanamycin resistant Escherichia coli SNO301-1 harboring pEC1C carrying ampC, ampR from Enterobacter cloacae after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1158655 | Antibacterial activity against Escherichia coli grown in sheep blood agar media assessed as concentration required to inhibit bacterial growth due to absence of hemolysis of erythrocytes after 18 hrs by ten-fold broth dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Eremophilane-type sesquiterpenoids with diverse skeletons from Ligularia sagitta. |
| AID495336 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with Ile449Val, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID206080 | In vitro inhibitory activity against Streptococci EryR (27);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID565431 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 biofilm assessed as biofilm bacterial count at 0.04 ug/ml (Rvb =402.9 +/- 26.88 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID644239 | Antibacterial activity against Staphylococcus aureus clinical isolate after 16 to 20 hrs by two fold agar dilution method | 2012 | European journal of medicinal chemistry, Mar, Volume: 49 | Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2. |
| AID1888846 | Antibacterial activity against Staphylococcus aureus 1199B measured after 24 hrs by Muller Hinton broth based MTT assay | 2022 | Bioorganic & medicinal chemistry, 01-15, Volume: 54 | Potentiating the intracellular killing of Staphylococcus aureus by dihydroquinazoline analogues as NorA efflux pump inhibitor. |
| AID278544 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium thermophilum ATCC 25866 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID572265 | Antibacterial activity against Prevotella melaninogenica by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID208612 | In vitro antibacterial activity against clinical isolates Ampicillin-insensitive Streptococcus pneumoniae was determined | 1995 | Journal of medicinal chemistry, Jun-09, Volume: 38, Issue:12 | Synthesis and biological evaluation of a series of new parenteral optically active 3-[[(N-alkylpyridinium-4'-yl)thio]methyl]-2-oxaisocephems. |
| AID1721974 | Antibacterial activity against Erwinia carotovora by microdilution method | 2020 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 30, Issue:17 | New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. |
| AID1457502 | Antibacterial activity against Bacillus subtilis assessed as inhibition of DNA synthesis at 2 mg/L after 50 mins by [3H]thymidine incorporation assay | 2017 | Journal of medicinal chemistry, 07-27, Volume: 60, Issue:14 | Lipophosphonoxins II: Design, Synthesis, and Properties of Novel Broad Spectrum Antibacterial Agents. |
| AID278236 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-2 with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID529579 | Ratio of Kcat to Km for Legionella gormanii ATCC 33297T beta-Lactamase FEZ-1 | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora. |
| AID1372809 | Bactericidal activity against Pseudomonas aeruginosa ATCC 9027 by two-fold serial dilution assay | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2 | An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold. |
| AID1457507 | Antibacterial activity against Bacillus subtilis assessed as inhibition of RNA synthesis at 2 mg/L after 50 mins by [3H]-uridine incorporation assay | 2017 | Journal of medicinal chemistry, 07-27, Volume: 60, Issue:14 | Lipophosphonoxins II: Design, Synthesis, and Properties of Novel Broad Spectrum Antibacterial Agents. |
| AID1577956 | Antimicrobial activity against Escherichia coli ATCC 25922 under iron-sufficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID534985 | Antimicrobial activity against Clostridium aminobutyricum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID447436 | Antibacterial activity against Staphylococcus aureus ATCC 6538P after 24 hrs by microtitration method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and antibacterial activity of 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-pyrazol-4-yl]-5-(substituted-phenyl)-[1,3,4]oxadiazoles. |
| AID537662 | Antibacterial activity against Enterobacter aerogenes ATCC 13048 after 18 hrs by agar-well diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Cyclization of some carbothioamide derivatives containing antipyrine and triazole moieties and investigation of their antimicrobial activities. |
| AID533382 | Antimicrobial activity against Bacteroides nordii by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID582967 | Antimicrobial activity against beta-lactamase B-deficient Yersinia enterocolitica GY5542 after 20 hrs by Etest | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Contribution of BlaA and BlaB beta-lactamases to antibiotic susceptibility of Yersinia enterocolitica biovar 1B. |
| AID293871 | Antibacterial activity against Enterobacter aerogenes CMCC(B) 45103 after 24 hrs by two fold dilution method | 2007 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 17, Issue:6 | Synthesis of pseudopeptides based L-tryptophan as a potential antimicrobial agent. |
| AID750274 | Antifungal activity against Aspergillus niger MTCC 282 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. |
| AID644168 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID657436 | Antibacterial activity against vancomycin-susceptible Enterococcus faecalis after 16 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9 | Preparation, antibacterial evaluation and preliminary structure-activity relationship (SAR) study of benzothiazol- and benzoxazol-2-amine derivatives. |
| AID424715 | Antibacterial activity against Bacillus subtilis | 2009 | Journal of natural products, Apr, Volume: 72, Issue:4 | Limazepines A-F, pyrrolo[1,4]benzodiazepine Antibiotics from an Indonesian Micrococcus sp. |
| AID1399529 | Antibacterial activity against drug-resistant Escherichia coli after 24 hrs by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID463413 | Antimicrobial activity against Streptococcus pyogenes after 24 hrs by liquid dilution method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines. |
| AID1235345 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 assessed as zone of inhibition at 2862 uM incubated overnight at 37 degC | 2015 | Journal of natural products, Jul-24, Volume: 78, Issue:7 | Phytochemical Investigation of the Constituents Derived from the Australian Plant Macropidia fuliginosa. |
| AID531602 | Antimicrobial activity against Escherichia coli JM109 harboring pE1MD plasmid expressing beta-lactamase SHV-56 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae. |
| AID523891 | Antimicrobial activity against Acinetobacter baumannii ATCC 15151 harboring plasmid AT801 by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan. |
| AID535217 | Antimicrobial activity against Clostridium symbiosum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID278234 | Antimicrobial activity against Salmonella enterica serovar Typhimurium GyrA S21-1 acrAB::Kan with GyrA S83F mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1627300 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by broth microdilution method | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16 | New antibacterial agents: Hybrid bioisoster derivatives as potential E. coli FabH inhibitors. |
| AID573353 | Antibacterial activity against ceftazidime-susceptible Escherichia coli assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1411633 | Bactericidal activity against Salmonella typhimurium ATCC 13311 incubated for 24 hrs followed by serial sub-cultivation and measured after 24 hrs by microdilution method | |||
| AID368418 | Antimicrobial activity against multidrug-resistant Escherichia coli C316 pHPA containing mutated GyrA gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID559346 | Antimicrobial activity against Salmonella spp. harboring oxa-1-like gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID520711 | Antibacterial activity against Escherichia coli TOP10 harboring pOXA-58 | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID1769806 | Antimicrobial activity against Staphylococcus aureus Sau 1862 assessed as inhibition of bacterial growth incubated for 16 to 18 hrs by broth micro dilution technique | |||
| AID1209735 | Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake at 500 uM over 20 mins relative to untreated-control | 2013 | Drug metabolism and disposition: the biological fate of chemicals, Apr, Volume: 41, Issue:4 | Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics. |
| AID1585667 | Antibacterial activity against methicillin-resistant Staphylococcus aureus assessed as zone of inhibition at 10 ug/mL after 24 hrs by agar disc diffusion method | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug resistance of bacterial infections. |
| AID85945 | The compound was tested in vitro for antibacterial activity against 47 strains of Haemophilus influenza AmpS; Value is 0.3/0.6 | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21 | Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens. |
| AID567770 | Antimicrobial activity against Staphylococcus aureus ATCC 6538 assessed as >99.9 % reduction in CFU after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID425595 | Antibacterial activity against Escherichia coli isolate HM605 isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as killing of bacteria at 100 ug/ml | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID399614 | Antimicrobial activity against Enterobacter cloacae ATCC 23355 at 0.1 mg/disk by disk diffusion assay | |||
| AID633858 | Antibacterial activity against Micrococcus flavus ATCC 10240 incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID1769950 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID546950 | Antibacterial activity against Shigella sonnei assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1243993 | Antimicrobial activity against Staphylococcus aureus by agar dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | Design and synthesis of some new pyrazolyl-pyrazolines as potential anti-inflammatory, analgesic and antibacterial agents. |
| AID396032 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pAP3 plasmid containing Enterobacter aerogenes acrR gene by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID1374417 | Antibacterial activity against Staphylococcus aureus ATCC 25925 | 2018 | Bioorganic & medicinal chemistry letters, 03-01, Volume: 28, Issue:5 | Synthesis, antimicrobial activity and acid dissociation constants of methyl 5,5-diphenyl-1-(thiazol-2-yl)pyrrolidine-2-carboxylate derivatives. |
| AID426135 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 at 100 ug/ml after 24 hrs by agar well diffusion method | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis and antimicrobial studies of novel methylene bridged benzisoxazolyl imidazo[2,1-b][1,3,4]thiadiazole derivatives. |
| AID555481 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 14 by Etest method in presence of cloxacillin and efflux pump inhibitor CCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID585427 | Antimicrobial activity against oqxAB positive Escherichia coli C600 XT11-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID112357 | In Vivo evaluation for its effective dose against Haemophilus influenzae (351TO19 AmpR beta (-)) | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID548471 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID587963 | Activity of Escherichia coli beta-lactamase Toho-1 D240S mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID1132065 | Antiviral activity against influenza A virus NWS/H0N1 infected in BHK cells at 1 mg/ml by agar diffusion assay | 1978 | Journal of medicinal chemistry, Jan, Volume: 21, Issue:1 | Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. |
| AID255558 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 16.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID534931 | Antimicrobial activity against Desulfovibrio desulfuricans by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID585422 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W245-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID573384 | Antibacterial activity against beta lactamase-positive Haemophilus influenzae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID775961 | Antibacterial activity against Klebsiella pneumoniae ATCC 13883 assessed as growth inhibition at 100 ug/mL after 18 to 24 hrs by microdilution assay | 2013 | European journal of medicinal chemistry, Nov, Volume: 69 | Synthesis, antibacterial and antioxidant activities of new 1-alkyl-4-(1-alkyl-4-oxo-1,4-dihydroquinolin-2-yl)pyridinium bromides. |
| AID1433840 | Antibacterial activity against Escherichia coli MTCC 443 after 24 to 48 hrs by broth microdilution method | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs. |
| AID555212 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 128 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1079938 | Chronic liver disease either proven histopathologically, or through a chonic elevation of serum amino-transferase activity after 6 months. Value is number of references indexed. [column 'CHRON' in source] | |||
| AID545445 | Antimicrobial activity against extended-spectrum beta-lactamase-positive Klebsiella pneumoniae assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID1399527 | Antibacterial activity against drug-resistant Pseudomonas aeruginosa after 24 hrs by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID509709 | Antibacterial activity against Staphylococcus epidermidis at 50 ug/ml after 24 hrs by agar cup diffusion method | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of some 3-substituted amino-4,5-tetramethylene thieno[2,3-d][ 1,2,3]-triazin-4(3H)-ones as potential antimicrobial agents. |
| AID1604666 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by visual method | |||
| AID389008 | Antibacterial activity against Bacillus subtilis ATCC 6051 by dilution assay | 2008 | Bioorganic & medicinal chemistry, Dec-01, Volume: 16, Issue:23 | Hetero-Diels-Alder reaction of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with arylsulfonylcyanides. Synthesis and antimicrobial activity of 4-hydroxy-2-(arylsulfonyl)pyridines. |
| AID555471 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 14 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID572056 | Antibacterial activity against Bifidobacterium longum by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID489645 | Antibacterial activity against Acinetobacter baumannii ATCC 19606 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID1577946 | Antimicrobial activity against Pseudomonas aeruginosa KW799 under iron-sufficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID1265687 | Toxicity in Paracoccus sp. 4M6 assessed as growth inhibition at 100 uM after 15 hrs by Syto61 based-fluorescence analysis relative to control | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Click-based synthesis of bromotyrosine alkaloid analogs as potential anti-biofilm leads for SAR studies. |
| AID255556 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 8.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID1055310 | Antibacterial activity against Bacillus subtilis at 10 ug after 24 hrs by disk diffusion method | 2013 | European journal of medicinal chemistry, , Volume: 70 | Phosphorus-nitrogen compounds part 27. Syntheses, structural characterizations, antimicrobial and cytotoxic activities, and DNA interactions of new phosphazenes bearing secondary amino and pendant (4-fluorobenzyl)spiro groups. |
| AID585016 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 335913 | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Inhibition of bacterial multidrug resistance by celecoxib, a cyclooxygenase-2 inhibitor. |
| AID1879067 | Antibacterial activity against pET28a-NDM-1 positive Escherichia coli BL21(DE3) isolates assessed as inhibition of bacterial growth incubated for 18 to 24 hrs by CLSI based broth microdilution method | 2022 | European journal of medicinal chemistry, Mar-05, Volume: 231 | Metallo-β-lactamases inhibitor fisetin attenuates meropenem resistance in NDM-1-producing Escherichia coli. |
| AID324222 | Antibacterial activity against Escherichia coli K12 containing PhoU mutant assessed as cell count in log phase at 100 ug/ml after 3 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1079943 | Malignant tumor, proven histopathologically. Value is number of references indexed. [column 'T.MAL' in source] | |||
| AID585399 | Activity at Fluoribacter gormanii 1K07 metallo-beta-lactamase FEZ-1 | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides. |
| AID1079936 | Choleostatic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is < 2 (see ACUTE). Value is number of references indexed. [column 'CHOLE' in source] | |||
| AID1471046 | Antibacterial activity against Pseudomonas fluorescens NCIM 2059 measured after 8 hrs | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID395349 | Antibacterial activity against Escherichia coli ATCC 11230 at 1 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID544286 | Antimicrobial activity against Enterococcus faecalis NKH16 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID438298 | Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2X preincubated for 4 hrs before addition of substrate (R)-[2-(benzoylamino)propionylsulfanyl]acetic acid | 2009 | Journal of medicinal chemistry, Oct-08, Volume: 52, Issue:19 | Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening. |
| AID573350 | Antibacterial activity against ceftazidime-nonsusceptible Enterobacter cloacae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID622560 | Antimicrobial activity against Salmonella typhi MTCC 98 for 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 21, Issue:20 | Microwave assisted synthesis and antimicrobial evaluation of new fused pyran derivatives bearing 2-morpholinoquinoline nucleus. |
| AID655702 | Antibacterial activity against Burkholderia pseudomallei NTCC 10274 after 24 hrs by serial broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID585875 | Antimicrobial activity against Pseudomonas aeruginosa isolate 18 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1399495 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hrs by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID1647639 | Antibacterial activity against Enterococcus faecium ATCC 19434 assessed as reduction in microbial growth | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Isocadiolides A-H: Polybrominated Aromatics from a |
| AID584297 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus fleurettii SFMP07 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID765497 | Antimicrobial activity against Enterococcus faecium D344R at 2 ug/ml after 18 hrs by disk diffusion method | 2013 | European journal of medicinal chemistry, Sep, Volume: 67 | Discovery of the first inhibitors of bacterial enzyme D-aspartate ligase from Enterococcus faecium (Aslfm). |
| AID1304319 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 25923 assessed as zone of inhibition at 10 ug after 18 hrs by disk diffusion method | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | Caged xanthones: Potent inhibitors of global predominant MRSA USA300. |
| AID546931 | Antibacterial activity against Salmonella enterica serovar Typhi assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1365609 | Antibacterial activity against Streptococcus pyogenes MTCC 442 | 2017 | Bioorganic & medicinal chemistry, 11-01, Volume: 25, Issue:21 | Recently reported biological activities of pyrazole compounds. |
| AID573336 | Antibacterial activity against ceftazidime-susceptible Enterobacteriaceae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID563503 | Antimicrobial activity against cetylpyridinium chloride-sensitive Serratia marcescens 79 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID567459 | Antimicrobial activity against Escherichia coli W3110 transformant harboring bla CTX-M-15 gene by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Plasmid-mediated resistance to cephalosporins in Salmonella enterica serovar Typhi. |
| AID630654 | Antibacterial activity against multidrug-resistant Staphylococcus aureus 3SP/R33 after 18 hrs | 2011 | Bioorganic & medicinal chemistry, Nov-01, Volume: 19, Issue:21 | Synthesis, molecular modeling and preliminary biological evaluation of a set of 3-acetyl-2,5-disubstituted-2,3-dihydro-1,3,4-oxadiazole as potential antibacterial, anti-Trypanosoma cruzi and antifungal agents. |
| AID395350 | Antibacterial activity against Staphylococcus aureus ATCC 6538 at 1 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID572031 | Antibacterial activity against Clostridium subterminale by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID396027 | Antibacterial activity against drug-resistant Enterobacter cloacae EcDC64 isolate expressing AcrAB-TolC efflux pump in presence of 20 ug/ml efflux pump inhibitor Phe-Arg-beta-naphthylamide by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID520719 | Antibacterial activity against Escherichia coli DH10B | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID572044 | Antibacterial activity against Clostridium sordellii by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID555247 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 60 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID584471 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN01 (ATCC 51145T) by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID1306203 | Bactericidal activity against Staphylococcus aureus ATCC 25923 after 18 hrs by microbroth dilution assay | 2016 | Bioorganic & medicinal chemistry, 07-15, Volume: 24, Issue:14 | The influence of halogen substituents on the biological properties of sulfur-containing flavonoids. |
| AID743894 | Antibacterial activity against Staphylococcus aureus at 5 mg/mL after 24 hrs | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of fused [1,3,4]thiadiazoles. |
| AID420227 | Antimicrobial activity against multidrug-resistant Enterococcus faecalis H.C. 24962 isolate after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID278551 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium infantis ATCC 15697 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1183257 | Antimicrobial activity against Streptococcus pneumoniae MTCC 1936 assessed as absence of visible growth after 24 to 48 hrs by broth micro dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis and characterization of fluoro substituted novel pyrazolylpyrazolines scaffold and their pharmacological screening. |
| AID478779 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5 | Synthesis, spectroscopic and biological studies on the new symmetric Schiff base derived from 2,6-diformyl-4-methylphenol with N-aminopyrimidine. |
| AID534981 | Antimicrobial activity against Clostridium perfringens by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID530234 | Antimicrobial activity against wild-type Mycobacterium bovis BCG by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1423479 | Antibacterial activity against Enterobacter cloacae subsp. cloacae ATCC 13047 after 24 hrs by bacterial proliferation assay | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID1592957 | Antibacterial activity against multi-drug resistant Escherichia coli NMI 3548/14 assessed as reduction in microbial growth incubated for 20 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. |
| AID529745 | Antibacterial activity against Beta-lactamase positive Haemophilus influenzae harboring fst1 mutant gene assessed as resistant isolates after 20 to 24 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID573356 | Antibacterial activity against ceftazidime-nonsusceptible Escherichia coli assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID573358 | Antibacterial activity against ceftazidime-susceptible Klebsiella pneumoniae by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID533358 | Antimicrobial activity against Bacteroides ovatus by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID765558 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 18 to 24 hrs by double microdilution method | 2013 | European journal of medicinal chemistry, Sep, Volume: 67 | Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities. |
| AID1744565 | Inhibition of Staphylococcus aureus FabH A81V/A111T mutant assessed as bacterial growth inhibition measured after 18 hrs by resazurin dye based broth dilution assay | 2021 | ACS medicinal chemistry letters, Mar-11, Volume: 12, Issue:3 | Semisynthesis and Biological Evaluation of Platencin Thioether Derivatives: Dual FabF and FabH Inhibitors against MRSA. |
| AID543794 | Antimicrobial activity against Klebsiella pneumoniae VT 1367 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID512147 | Antibacterial activity against Escherichia coli MTCC 41 at 64 mg/ml after 16 hrs by disk diffusion test | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antiviral and antibacterial agents. |
| AID1412934 | Bactericidal activity against Enterobacter cloacae clinical isolate by microdilution method | 2018 | MedChemComm, May-01, Volume: 9, Issue:5 | Design, synthesis and antimicrobial activity of usnic acid derivatives. |
| AID1304338 | Bactericidal activity against methicillin-resistant Staphylococcus aureus USA300 SF8300 after 18 to 20 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | Caged xanthones: Potent inhibitors of global predominant MRSA USA300. |
| AID283558 | Antibacterial activity against Escherichia coli AG102 with marR1 mutation after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. |
| AID198150 | In vitro antibacterial activity against GN 12873 strain of Stenotrophomonas maltophilia | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID533424 | Antimicrobial activity against Anaerococcus prevotii assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID565750 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecalis clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID372554 | Antibacterial activity against genetically beta-lactamase-negative ampicillin-resistant Haemophilus influenzae type b with an amino acid substitution in variable mutated locus Asn-526 or Arg-517 of ftsI gene assessed as susceptibility rate by broth microd | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID548032 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237R mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID422882 | Antimicrobial activity against Acinetobacter baumannii-Acinetobacter calcoaceticus complex isolated from diabetic patient with calcaneal osteomyelitis by broth microdilution assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Development of colistin-dependent Acinetobacter baumannii-Acinetobacter calcoaceticus complex. |
| AID562356 | Antimicrobial activity against erythromycin-, streptomycin-resistant Enterococcus faecium TX1330RF-A1 conjugant expressing hylEfm gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Cotransfer of antibiotic resistance genes and a hylEfm-containing virulence plasmid in Enterococcus faecium. |
| AID1331874 | Antibacterial activity against Enterobacter cloacae ATCC 13047 | 2017 | Bioorganic & medicinal chemistry, 01-01, Volume: 25, Issue:1 | Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. |
| AID325448 | Antibacterial activity against Staphylococcus aureus Mu50 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID547793 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237V mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID555451 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 109 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID43904 | Beta-lactamase inhibitory activity against penicillinase of Staphylococcus aureus 1840 | 1983 | Journal of medicinal chemistry, May, Volume: 26, Issue:5 | Synthesis and biological activities of the Z isomers of carbapenem antibiotics. |
| AID523892 | Antimicrobial activity against Acinetobacter baumannii ATCC 15151 harboring ISAba1-blaOXA-23 gene by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan. |
| AID548009 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237Q mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID147030 | The compound was tested for minimal inhibitory concentration against Penicillinase producing Neisseria gonorrhoeae (PPNG) | 2002 | Bioorganic & medicinal chemistry letters, Sep-02, Volume: 12, Issue:17 | The activity of p-methoxybenzylisothiocyanate against Neisseria gonorrhoeae, Haemophilus ducreyi, and other microorganisms. |
| AID529618 | Antibacterial activity against Beta-lactamase positive Haemophilus influenzae isolate after 20 to 24 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID559348 | Antimicrobial activity against Salmonella spp. harboring oxa-5-like gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID514132 | Antibacterial activity against Escherichia coli 1655 assessed as growth inhibition at 1 mg/ml after 16 to 20 hrs in presence of 0.2 mM L-histidine | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays. |
| AID565749 | Antimicrobial activity against Enterococcus faecalis expressing VanA gene clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID587982 | Antibacterial activity against Escherichia coli AS226 carrying pBSDD240A mutant after 18 hrs by broth microdilution method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID549335 | Antimicrobial activity against Escherichia coli isolate Z1 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID555458 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 60 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID324239 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 assessed as cell count in stationary phase at 100 ug/ml after 10 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID572053 | Antibacterial activity against Bifidobacterium breve by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1185705 | Antimicrobial activity against Mycobacterium smegmatis ATCC 607 after 24 hrs by agar dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | New thiophene-1,2,4-triazole-5(3)-ones: highly bioactive thiosemicarbazides, structures of Schiff bases and triazole-thiols. |
| AID304975 | Antifungal activity against Trichophyton mentagrophytes by broth micro-dilution technique | 2007 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1 | New antifungal flavonoid glycoside from Vitex negundo. |
| AID382684 | Antimicrobial activity against Escherichia coli ATCC 25922 at 572.4 uM by disc-diffusion method | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives. |
| AID582896 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87Q mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1870146 | Antibacterial activity against wild type Staphylococcus aureus 4460/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID519638 | Antimicrobial activity against ceftazidime-resistant Escherichia coli Irk2320 harboring beta-lactamase CTX-M-42 Pro167Thr mutant gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID540835 | Antimicrobial activity against Salmonella enterica serovar enteritidis isolate 104 harboring gyrA D87Y mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID547789 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237M mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID565432 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 biofilm assessed as biofilm bacterial count at 0.06 ug/ml (Rvb =402.9 +/- 26.88 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID1265204 | Bactericidal activity against Bacillus cereus ATCC 14579 after 24 hrs | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes. |
| AID278547 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium bifidum ATCC 15696 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID541149 | Antimicrobial activity against soxS::aph-deficient ciprofloxacin-resistant Salmonella enterica serovar enteritidis isolate 104-cip harboring gyrA D87Y,S83F mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID1868106 | Antibacterial activity against methicillin-resistant Staphylococcus aureus clinical isolate 9B assessed as inhibition of visible bacterial growth incubated for 18 hrs by CLSI protocol based assay | 2022 | Journal of natural products, 05-27, Volume: 85, Issue:5 | Enceleamycins A-C, Furo-Naphthoquinones from |
| AID494533 | Antimicrobial activity against Staphylococcus aureus NCIM 5021 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID494533 | Antimicrobial activity against Staphylococcus aureus NCIM 5021 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May-06 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID750275 | Antifungal activity against Candida albicans MTCC 227 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. |
| AID1225287 | Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 12 hrs at 37 degC | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Pentacyclic antibiotics from a tidal mud flat-derived actinomycete. |
| AID207966 | Minimum inhibitory concentration of Ampicillin required for growth inhibition of Beta lactamase producing bacteria Staphylococcus aureus (ATCC90124) | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8 | Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives. |
| AID562811 | Antimicrobial activity against Escherichia coli J53 harboring pEK204 plasmid encoding CTX-M extended-spectrum beta-lactamases | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID584330 | Antibacterial activity against ygiBC, yjfMC, gspS deficient Escherichia coli GD108 | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Interplay between drug efflux and antioxidants in Escherichia coli resistance to antibiotics. |
| AID1265773 | Antibacterial activity against clinical isolate methicillin-resistant Staphylococcus aureus by two-fold serial dilution method | 2016 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 26, Issue:1 | Discovery of bisindolyl-substituted cycloalkane-anellated indoles as novel class of antibacterial agents against S. aureus and MRSA. |
| AID471907 | Antibacterial activity against Escherichia coli MTCC 41 after 12 to 16 hrs | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | A facile one-pot green synthesis and antibacterial activity of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes. |
| AID565748 | Antimicrobial activity against Enterococcus faecalis expressing VanB gene clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID546972 | Antibacterial activity against Aeromonas sobria by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID373680 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by broth microdilution method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID548006 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237P mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID587985 | Antibacterial activity against Escherichia coli AS226 carrying pBSD6 mutant after 18 hrs by broth microdilution method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID522392 | Ratio of Kcat Km for Aeromonas enteropelogenes Beta-lactamase TRU1 | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Genetic and biochemical characterization of TRU-1, the endogenous class C beta-lactamase from Aeromonas enteropelogenes. |
| AID530516 | Antimicrobial activity against group B Streptococcus sp. 'group B' isolate 7368-04 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID548472 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID584332 | Antibacterial activity against tolC, gshB deficient Escherichia coli GD107 | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Interplay between drug efflux and antioxidants in Escherichia coli resistance to antibiotics. |
| AID781325 | pKa (acid-base dissociation constant) as determined by Liao ref: J Chem Info Model 2009 | 2014 | Pharmaceutical research, Apr, Volume: 31, Issue:4 | Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. |
| AID555249 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 65 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID420222 | Antimicrobial activity against multidrug-resistant Staphylococcus aureus H.C. 20794 isolate after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID362535 | Antibacterial activity against Micrococcus luteus assessed as zone of inhibition at 0.25 mg/mL by agar well diffusion method | 2008 | Journal of natural products, Aug, Volume: 71, Issue:8 | Bioactive 5alpha-pregnane-type steroidal alkaloids from Sarcococca hookeriana. |
| AID633489 | Antibacterial activity against Salmonella Typhimurium ATCC 14028 after 24 hrs by two fold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial activity of brominated resorcinol dimers. |
| AID557704 | Antimicrobial activity in Prevotella sp.by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID539556 | Antimicrobial activity against Staphylococcus aureus ATCC 6538p | 2010 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 20, Issue:23 | Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase. |
| AID555255 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 69 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID536086 | Antimicrobial activity against Candida albicans IFO 0583 at 100 ug/8 mm disk after 48 hrs by agar disk diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID545144 | Activity of CMY-2 by spectrophotometry | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids. |
| AID1201595 | Antibacterial activity against Bacillus subtilis ATCC 6633 assessed as growth inhibition after 24 hrs by turbidimetric analysis | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Pentacyclic triterpene derivatives possessing polyhydroxyl ring A inhibit gram-positive bacteria growth by regulating metabolism and virulence genes expression. |
| AID324983 | Antibacterial activity against Haemophilus influenzae MSC02022 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID555459 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 60 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID395735 | Antimicrobial activity against imipenem-susceptible invasive nontypeable Haemophilus influenzae isolate 251 by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | First characterization of heterogeneous resistance to imipenem in invasive nontypeable Haemophilus influenzae isolates. |
| AID562937 | Upregulation of cwp84 gene expression in Clostridium difficile CD07-259 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID1180294 | Bactericidal activity against Staphylococcus aureus NCIM-2901 after 72 hrs by two fold serial macrodilution technique | 2014 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15 | One pot three components microwave assisted and conventional synthesis of new 3-(4-chloro-2-hydroxyphenyl)-2-(substituted) thiazolidin-4-one as antimicrobial agents. |
| AID531315 | Activity of Pseudomonas aeruginosa beta-lactamase VIM-2 by spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family. |
| AID548013 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237S mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID528700 | Antibacterial activity against vancomycin resistant Enterococcus faecalis VanA clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID534937 | Antimicrobial activity against Desulfovibrio vulgaris by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID555467 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 90 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1767662 | Antibacterial activity against Enterococcus faecalis ATCC 29212 assessed as inhibition of bacterial growth incubated for 24 hrs by microdilution assay | 2021 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 47 | Antimicrobial, modulatory, and antibiofilm activity of tt-farnesol on bacterial and fungal strains of importance to human health. |
| AID324297 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoBR mutant assessed as cell count in stationary phase at 100 ug/ml after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID529589 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-12 assessed as bacterial density at 512 ug/ml after 18 hrs | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID562385 | Antimicrobial activity against Enterococcus faecalis expressing VanB gene clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1695861 | Antibacterial activity against Bacillus cereus ATCC 6630 incubated for 24 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID318660 | Antibacterial activity against Peptostreptococcus asaccharolyticus GAI 5534 by broth microdilution method | 2008 | Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7 | Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens. |
| AID572035 | Antibacterial activity against Clostridium butyricum by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID1231415 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition at 20 ug after 24 hrs by disc agar diffusion method in presence of sulbactam | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and biological evaluation of caracasine acid derivatives. |
| AID1337799 | Antibacterial activity against Pseudomonas fluorescens NCIM 2036 measured after 8 hrs | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Quinolidene-rhodanine conjugates: Facile synthesis and biological evaluation. |
| AID776461 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 43288 at 10 ug | 2013 | European journal of medicinal chemistry, Nov, Volume: 69 | Design, synthesis and biological activities of some 7-aminocephalosporanic acid derivatives. |
| AID1055637 | Antibacterial activity against Staphylococcus aureus MTCC 96 assessed as growth inhibition at 1 mg/mL after 24 hrs by two-fold serial dilution method | 2013 | European journal of medicinal chemistry, , Volume: 70 | Synthesis and antimicrobial activity of some novel hydrazide, benzochromenone, dihydropyridine, pyrrole, thiazole and thiophene derivatives. |
| AID1769816 | Antimicrobial activity against Candida albicans assessed as inhibition of bacterial growth incubated for 16 to 18 hrs by broth micro dilution technique | |||
| AID572046 | Antibacterial activity against Clostridium sporogenes by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID324306 | Antibacterial activity against Escherichia coli K12 containing deletion deltahipA mutant assessed as cell count in log phase at 100 ug/ml after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID533392 | Antimicrobial activity against Clostridium perfringens assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID510749 | Antibacterial activity against Escherichia coli AG102MB harboring pP10-based acrB gene | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. |
| AID530226 | Antimicrobial activity against Mycobacterium bovis BCG ML1012 carrying transposon IS1096::Km inserted at +1255bp of bcg3960c gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1504827 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 after 24 hrs by broth microdilution method | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12 | Sulfur-Containing Aristoloxazines and Other Constituents of the Roots of Aristolochia orbicularis. |
| AID670271 | Antibacterial activity against Micrococcus luteus IFC 12708 after 24 hrs | 2012 | Bioorganic & medicinal chemistry, Jul-01, Volume: 20, Issue:13 | Beta-carboline alkaloids derived from the ascidian Synoicum sp. |
| AID369629 | Antimicrobial activity against beta-lactamase negative ampicillin-resistant Haemophilus influenzae by E-test | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Can the Etest correctly determine the MICs of beta-lactam and cephalosporin antibiotics for beta-lactamase-negative ampicillin-resistant Haemophilus influenzae? |
| AID496399 | Antibacterial activity against azide-resistant Escherichia coli J53 TET2 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID533876 | Antibacterial activity against amoxicillin-intermediate Streptococcus pneumoniae isolate by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | In vitro activity of ceftaroline against Streptococcus pneumoniae isolates exhibiting resistance to penicillin, amoxicillin, and cefotaxime. |
| AID1176777 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 after 24 hrs by broth microdilution method | 2015 | Journal of natural products, Jan-23, Volume: 78, Issue:1 | Structure and antimicrobial activity of phloroglucinol derivatives from Achyrocline satureioides. |
| AID530227 | Antimicrobial activity against Mycobacterium bovis BCG ML1034 carrying transposon IS1096::Km inserted at -54bp of bcg0231 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID542720 | Antimicrobial activity against ESBL-producing Klebsiella pneumoniae clinical isolate assessed as susceptible isolates | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Widespread dissemination of aminoglycoside resistance genes armA and rmtB in Klebsiella pneumoniae isolates in Taiwan producing CTX-M-type extended-spectrum beta-lactamases. |
| AID1434051 | Antibacterial activity against Bacillus subtilis NCIM 2063 by standard agar method | 2017 | Bioorganic & medicinal chemistry letters, 02-01, Volume: 27, Issue:3 | Antileishmanial evaluation of clubbed bis(indolyl)-pyridine derivatives: One-pot synthesis, in vitro biological evaluations and in silico ADME prediction. |
| AID306208 | Antimicrobial activity against Vibrio harveyi | 2007 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 17, Issue:5 | Anti-mycobacterial activity of a bis-sulfonamide. |
| AID533396 | Antimicrobial activity against Clostridium innocuum assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID1180291 | Antimicrobial activity against Bacillus subtilis NCIM-2063 after 20 hrs by two fold serial macrodilution technique | 2014 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15 | One pot three components microwave assisted and conventional synthesis of new 3-(4-chloro-2-hydroxyphenyl)-2-(substituted) thiazolidin-4-one as antimicrobial agents. |
| AID1201596 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition after 24 hrs by turbidimetric analysis | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Pentacyclic triterpene derivatives possessing polyhydroxyl ring A inhibit gram-positive bacteria growth by regulating metabolism and virulence genes expression. |
| AID386968 | Antimicrobial activity Bacillus thuringiensis at 25 ug/mL after 24 hrs by agar diffusion technique | 2008 | European journal of medicinal chemistry, Oct, Volume: 43, Issue:10 | Synthesis and antimicrobial activity of some new heterocycles incorporating antipyrine moiety. |
| AID477409 | Antibacterial activity against Staphylococcus aureus NCTC 8325 after 16 to 20 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR. |
| AID518728 | Activity of Pseudomonas stutzeri beta-lactamase DIM-1 by UV-spectrophotometry | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Characterization of DIM-1, an integron-encoded metallo-beta-lactamase from a Pseudomonas stutzeri clinical isolate in the Netherlands. |
| AID509703 | Antibacterial activity against Escherichia coli after 24 hrs by tube dilution method | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of some 3-substituted amino-4,5-tetramethylene thieno[2,3-d][ 1,2,3]-triazin-4(3H)-ones as potential antimicrobial agents. |
| AID1852760 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 assessed as bacterial growth inhibition by broth microdilution assay | 2022 | RSC medicinal chemistry, Sep-21, Volume: 13, Issue:9 | Design and evaluation of poly-nitrogenous adjuvants capable of potentiating antibiotics in Gram-negative bacteria. |
| AID1104317 | Antibacterial activity against Salmonella enterica subsp. enterica serovar Typhimurium ATCC 13311 at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID360056 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as lactoyl tetra-aspartate-peptide level | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID573368 | Antibacterial activity against ceftazidime-susceptible Proteus mirabilis assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID547795 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237V mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID389004 | Antibacterial activity against Bacillus subtilis ATCC 6051 assessed as diameter of the inhibition zone at 1 uM/disk after 4 hrs by disk diffusion method | 2008 | Bioorganic & medicinal chemistry, Dec-01, Volume: 16, Issue:23 | Hetero-Diels-Alder reaction of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with arylsulfonylcyanides. Synthesis and antimicrobial activity of 4-hydroxy-2-(arylsulfonyl)pyridines. |
| AID405330 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae group IIc isolates with acrR base C insertion behind nucleotide 496 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID64591 | Minimum inhibitory concentration required for the inhibition of Escherichia coli ATCC 9637 | 1986 | Journal of medicinal chemistry, Jun, Volume: 29, Issue:6 | The lysine pathway as a target for a new genera of synthetic antibacterial antibiotics? |
| AID565624 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.08 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =793.3 +/- 42.40 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID1412932 | Bactericidal activity against Escherichia coli ATCC 35210 by microdilution method | 2018 | MedChemComm, May-01, Volume: 9, Issue:5 | Design, synthesis and antimicrobial activity of usnic acid derivatives. |
| AID526303 | Antimicrobial activity against Streptococcus pyogenes by agar plate disk diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Bernthsen synthesis, antimicrobial activities and cytotoxicity of acridine derivatives. |
| AID1337800 | Antibacterial activity against of Staphylococcus aureus NCIM 2010 measured after 12 hrs | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Quinolidene-rhodanine conjugates: Facile synthesis and biological evaluation. |
| AID731204 | Antibacterial activity against Streptococcus pneumoniae MTCC 1936 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles. |
| AID1265692 | Antibiofilm activity against Pseudoalteromonas ulvae TC14 assessed as reduction in adhesion after 15 hrs by Syto61 based-fluorescence analysis relative to control | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Click-based synthesis of bromotyrosine alkaloid analogs as potential anti-biofilm leads for SAR studies. |
| AID584772 | Antimicrobial activity against Acinetobacter lwoffii isolate K expressing beta-lactamase OXA-58 isolated from blood culture of patient in presence of Sulbactam by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID528529 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B12 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID535195 | Antimicrobial activity against Clostridium nexile by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID447067 | Antibacterial activity against Proteus vulgaris ATCC 8427 at 10 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID547773 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237A mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID533372 | Antimicrobial activity against Bacteroides vulgatus assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID745308 | Antibacterial activity against Bacillus subtilis MTCC 441 assessed as growth inhibition after overnight incubation by NCCLS broth microdilution method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Synthesis and identification of β-aryloxyquinoline based diversely fluorine substituted N-aryl quinolone derivatives as a new class of antimicrobial, antituberculosis and antioxidant agents. |
| AID582965 | Antimicrobial activity against Yersinia enterocolitica Biovar 1B 8081 after 20 hrs by Etest | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Contribution of BlaA and BlaB beta-lactamases to antibiotic susceptibility of Yersinia enterocolitica biovar 1B. |
| AID285513 | Antibacterial activity against Klebsiella pneumoniae | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens. |
| AID529613 | Antibacterial activity against Beta-lactamase negative Haemophilus influenzae assessed as susceptible isolates after 20 to 24 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID477750 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | An eco-friendly synthesis and antimicrobial activities of dihydro-2H-benzo- and naphtho-1,3-oxazine derivatives. |
| AID1698868 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 15692 assessed as zone of inhibition at 2 mg/ml after 24 hrs by agar well diffusion method | 2020 | Journal of natural products, 10-23, Volume: 83, Issue:10 | Synthesis of Natural and Unnatural Quinolones Inhibiting the Growth and Motility of Bacteria. |
| AID322315 | Antibacterial activity against CTX-M group 1 enzyme producing Escherichia coli isolates assessed as percent nonsusceptible isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal. |
| AID548030 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237K mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID494166 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, characterization, in vitro and molecular docking studies of new 2,5-dichloro thienyl substituted thiazole derivatives for antimicrobial properties. |
| AID572255 | Antibacterial activity against Fusobacterium mortiferum by CLSI M11-A6 agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates. |
| AID535447 | Antimicrobial activity against Lactobacillus fermentum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID736474 | Antibacterial activity against Klebsiella pneumoniae RCMB 010093 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID535191 | Antimicrobial activity against Clostridium lactatifermentans by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID557426 | Antimicrobial activity in Bacteroides distasonis by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID557210 | Antibacterial activity against Beta-lactamase-negative Neisseria meningitidis assessed as percent intermediate isolates by Etest method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Antibiotic susceptibility and characteristics of Neisseria meningitidis isolates from the African meningitis belt, 2000 to 2006: phenotypic and genotypic perspectives. |
| AID324981 | Antibacterial activity against Haemophilus influenzae MSC02104 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID252616 | Mean lysis diameter of porin deficient Enterobacter aerogenes EA289 by standard disk diffusion method on MH agar | 2005 | Journal of medicinal chemistry, Mar-10, Volume: 48, Issue:5 | Beta-lactam screening by specific residues of the OmpF eyelet. |
| AID752007 | Antibacterial activity against Bacillus subtilis NCIM 2063 by broth dilution method | 2013 | Bioorganic & medicinal chemistry letters, May-01, Volume: 23, Issue:9 | Green synthesis of tetrahydropyrimidine analogues and evaluation of their antimicrobial activity. |
| AID1388187 | Antibacterial activity against Staphylococcus aureus MTCC 3381 incubated for 24 hrs by serial dilution method | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18 | Synthesis, antimicrobial activity, structure-activity relationship and cytotoxic studies of a new series of functionalized (Z)-3-(2-oxo-2-substituted ethylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ones. |
| AID633949 | Antibacterial activity against Enterococcus faecalis isolated from human incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID1265195 | Antibacterial activity against Proteus vulgaris ATCC 13315 after 24 hrs by microtiter plate method | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes. |
| AID334234 | Antimicrobial activity against Trichophyton mentagrophytes NCPF 224 after 10 days by microdilution technique | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4 | Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline. |
| AID1337798 | Antibacterial activity against Escherichia coli NCIM 2688 measured after 8 hrs | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Quinolidene-rhodanine conjugates: Facile synthesis and biological evaluation. |
| AID1827144 | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA100 assessed as inhibition of bacterial growth after 18 hrs in presence of oxacillin by CLSI protocol based broth microdilution assay | 2022 | ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3 | Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA. |
| AID585868 | Antimicrobial activity against Pseudomonas aeruginosa isolate 14 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1158653 | Antibacterial activity against Staphylococcus aureus grown in sheep blood agar media assessed as concentration required to inhibit bacterial growth due to absence of hemolysis of erythrocytes after 18 hrs by ten-fold broth dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Eremophilane-type sesquiterpenoids with diverse skeletons from Ligularia sagitta. |
| AID557986 | Antimicrobial activity in Clostridium bifermentans by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1706151 | Antibacterial activity against methicillin-resistant Staphylococcus aureus R3708 assessed as reduction in bacterial growth incubated for 18 hrs by CLSI based broth microdilution assay | |||
| AID266677 | Antibacterial activity against Pseudomonas aeruginosa | 2006 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 16, Issue:14 | Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives. |
| AID558325 | Antibacterial activity against bla gene-negative and nitrocefin reaction-negative beta-lactamase harboring Campylobacter jejuni isolate P850 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID208629 | In vitro antibacterial activity against clinical isolates Ampicillin-insensitive Streptococcus pneumoniae was determined | 1995 | Journal of medicinal chemistry, Jun-09, Volume: 38, Issue:12 | Synthesis and biological evaluation of a series of new parenteral optically active 3-[[(N-alkylpyridinium-4'-yl)thio]methyl]-2-oxaisocephems. |
| AID1209736 | Inhibition of human OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake at 500 uM over 20 mins relative to untreated-control | 2013 | Drug metabolism and disposition: the biological fate of chemicals, Apr, Volume: 41, Issue:4 | Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics. |
| AID1767665 | Antibacterial activity against Streptococcus agalactiae ATCC 13813 assessed as inhibition of bacterial growth incubated for 24 hrs by microdilution assay | 2021 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 47 | Antimicrobial, modulatory, and antibiofilm activity of tt-farnesol on bacterial and fungal strains of importance to human health. |
| AID584299 | Antibacterial activity against mecA-negative Staphylococcus fleurettii SFMN01 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID1185312 | Antibacterial activity Escherichia coli ATCC-25922 assessed as growth inhibition after 24 hrs by twofold serial dilution technique | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis and 3D-QSAR studies of new diphenylamine containing 1,2,4-triazoles as potential antitubercular agents. |
| AID548744 | Antimicrobial activity against Vancomycin-nonsusceptible Enterococcus faecium assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID1577958 | Antimicrobial activity against Klebsiella pneumoniae ATCC 8303 under iron-sufficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID555268 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 128 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID530339 | Activity of Pseudomonas aeruginosa VIM-13 beta-lactamase | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain. |
| AID530508 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype III isolate 7037-99 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID563966 | Antibacterial activity against Klebsiella pneumoniae 05-560 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. |
| AID1484008 | Antimicrobial activity against Staphylococcus aureus CECT976 assessed as growth inhibition zone after 18 hrs by disc diffusion method | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2 | Discovery of C-Glycosylpyranonaphthoquinones in Streptomyces sp. MBT76 by a Combined NMR-Based Metabolomics and Bioinformatics Workflow. |
| AID528741 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae ATCC BAA-611 harboring PBP-2X V405A mutant gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID532027 | Antimicrobial activity against Kluyvera georgiana 14751 expressing beta-lactamase CTX-M-78 obtained from bloodstream of patient by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. |
| AID1399256 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 29213 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID285206 | Antimicrobial activity against Escherichia coli AG112 mutant with marR genotype after 125 generations in absence of tetracycline | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID1157888 | Inhibition of sortase A (unknown origin) | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Suvanine sesterterpenes and deacyl irciniasulfonic acids from a tropical Coscinoderma sp. sponge. |
| AID1385489 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 by two-fold serial dilution method | 2018 | Journal of natural products, 08-24, Volume: 81, Issue:8 | Abyssomicin Monomers and Dimers from the Marine-Derived Streptomyces koyangensis SCSIO 5802. |
| AID533636 | Antimicrobial activity against Propionibacterium sp. by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID584305 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus vitulinus SVMP02 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID294413 | Antimicrobial activity against Bacillus subtilis at 25 ug/mL by agar diffusion technique | 2007 | European journal of medicinal chemistry, Jul, Volume: 42, Issue:7 | Synthesis and antimicrobial evaluation of some new thiazole, thiazolidinone and thiazoline derivatives starting from 1-chloro-3,4-dihydronaphthalene-2-carboxaldehyde. |
| AID441924 | Antibacterial activity against Bacillus anthracis Sterne after 24 hrs by NCCLS method | 2009 | Journal of medicinal chemistry, Nov-12, Volume: 52, Issue:21 | Coordination chemistry based approach to lipophilic inhibitors of 1-deoxy-D-xylulose-5-phosphate reductoisomerase. |
| AID495328 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with Asp350Asn, Met377Ile, Gly490Glu, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID535494 | Antimicrobial activity against beta-lactamase positive, ampicillin-clavulanic acid resistant Haemophilus influenzae expressing fst1 mutant gene assessed as resistant isolates by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Genotypic versus phenotypic characterization, with respect to beta-lactam susceptibility, of Haemophilus influenzae isolates exhibiting decreased susceptibility to beta-lactam resistance markers. |
| AID548033 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237R mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID633488 | Antibacterial activity against Micrococcus luteus IFC 12708 after 24 hrs by two fold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial activity of brominated resorcinol dimers. |
| AID547634 | Antimicrobial activity against Escherichia coli ATCC 25922 after 24 to 48 hrs by micro dilution susceptibility test | 2010 | European journal of medicinal chemistry, Dec, Volume: 45, Issue:12 | Synthesis and biological evaluation of some thiazolylpyrazole derivatives as dual anti-inflammatory antimicrobial agents. |
| AID1164945 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus NRS 70 by microbroth dilution method | 2014 | Journal of medicinal chemistry, Oct-23, Volume: 57, Issue:20 | Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives. |
| AID278562 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium breve R0070 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID333991 | Antibacterial activity against Salmonella typhi assessed per 100 uL of nutrient broth after 24 hrs by tube broth dilution method | 1997 | Journal of natural products, Oct, Volume: 60, Issue:10 | New steroidal alkaloids from Buxus longifolia. |
| AID360068 | Inhibition of Enterococcus faecium M512 PBPfm transpeptidase activity assessed as tetra-aspartate-tri multimer containing D-Ala4 to D-Asp-L-Lys3 cross links at 128 ug/ml by mass spectrometry | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID567581 | Antimicrobial activity against Acinetobacter baumannii assessed as susceptible isolate by broth dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | In vitro antimicrobial activity and mutant prevention concentration of colistin against Acinetobacter baumannii. |
| AID540968 | Ratio of Kcat to Km for Salmonella enterica serotype Newport AM17274 cephalosporinase CMY-31 by spectrophotometry | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids. |
| AID324165 | Antibacterial activity against Escherichia coli K12 mutant JHU313 at 100 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID585844 | Antimicrobial activity against Pseudomonas aeruginosa isolate 2 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID587974 | Ratio of Kcat to Km for Escherichia coli beta-lactamase Toho-1 C69A mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID590288 | Antibacterial activity against Salmonella Typhimurium ATCC 14028 after 24 hrs by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase. |
| AID644174 | Antibacterial activity against Micrococcus flavus ATCC 10240 treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID775555 | Antimicrobial activity against Pasteurella multocida clinical isolate after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21 | New derivatives of salicylamides: Preparation and antimicrobial activity against various bacterial species. |
| AID467607 | Antibacterial activity against Bacillus thuringiensis at 2 mg/ml by agar diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new thiazole and thiophene derivatives. |
| AID255559 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 128.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID542721 | Antimicrobial activity against ESBL-producing Klebsiella pneumoniae clinical isolate assessed as resistant isolates | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Widespread dissemination of aminoglycoside resistance genes armA and rmtB in Klebsiella pneumoniae isolates in Taiwan producing CTX-M-type extended-spectrum beta-lactamases. |
| AID545433 | Antimicrobial activity against Escherichia coli obtained from patient with complicated intra-abdominal infection assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID770919 | Antibacterial activity against Staphylococcus aureus IFO 3060 after 24 hrs by two fold dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID743895 | Antibacterial activity against Bacillus cereus at 5 mg/mL after 24 hrs | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of fused [1,3,4]thiadiazoles. |
| AID577208 | Antimicrobial activity against Escherichia coli C600::H19B in logarithmic phase encoding Stx-1 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID69322 | MIC against aerobic organism Escherichia coli strain 2891 | 1982 | Journal of medicinal chemistry, Apr, Volume: 25, Issue:4 | Quaternary heterocyclylamino beta-lactams: a generic alternative to the classical acylamino side chain. |
| AID465611 | Antibacterial activity against Staphylococcus aureus ATCC 65389 | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Discorhabdins from the Korean marine sponge Sceptrella sp. |
| AID1419479 | Antimicrobial activity against Aspergillus fumigatus 293 by two fold serial dilution method | 2017 | European journal of medicinal chemistry, May-05, Volume: 131 | Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents. |
| AID1139539 | Antibacterial activity against Escherichia coli DH5alpha expressing beta-lactamase SHV-12 by CLSI broth microdilution method | 2014 | Journal of medicinal chemistry, May-08, Volume: 57, Issue:9 | Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. |
| AID1853150 | Antibacterial activity against Macrolide sensitive Streptococcus pyogenes clinical isolate B0542 assessed as inhibition of bacterial growth incubated for 20 to 22 hrs by broth microdilution method | 2022 | RSC medicinal chemistry, Dec-14, Volume: 13, Issue:12 | Novel tetrahydropyrimidinyl-substituted benzimidazoles and benzothiazoles: synthesis, antibacterial activity, DNA interactions and ADME profiling. |
| AID1433841 | Antifungal activity against Candida albicans MTCC 227 after 24 to 48 hrs by broth microdilution method | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs. |
| AID341969 | Antimicrobial activity against Escherichia coli AJE0508 isolate carrying ISCR1 element related blaCTX-M-14 gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Novel complex class 1 integron bearing an ISCR1 element in an Escherichia coli isolate carrying the blaCTX-M-14 gene. |
| AID1278998 | Antibacterial activity against Bacillus subtilis incubated for 20 hrs by microbroth dilution method | 2016 | Bioorganic & medicinal chemistry, Mar-15, Volume: 24, Issue:6 | Synthesis of fluorinated carbazoles via C-H arylation catalyzed by Pd/Cu bimetal system and their antibacterial activities. |
| AID285367 | Decrease in susceptibility of qnrS-positive transconjugant streptomycin-resistant Escherichia coli C600 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Prevalence of plasmid-mediated quinolone resistance determinants QnrA, QnrB, and QnrS among clinical isolates of Enterobacter cloacae in a Taiwanese hospital. |
| AID666960 | Antibacterial activity against Streptococcus pneumoniae MTCC 1936 by broth microdilution method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | New N-arylamino biquinoline derivatives: synthesis, antimicrobial, antituberculosis, and antimalarial evaluation. |
| AID585855 | Antimicrobial activity against Pseudomonas aeruginosa isolate 8 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID570784 | Antimicrobial activity against multidrug-resistant Acinetobacter baumannii assessed as resistant isolates by disk diffusion method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | Genetic basis of multidrug resistance in Acinetobacter baumannii clinical isolates at a tertiary medical center in Pennsylvania. |
| AID555215 | Antibacterial activity against Escherichia coli DH5alpha carrying ampC gene of Acinetobacter genomosp. 3 isolate 14 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID557795 | Antimicrobial activity against Proteus mirabilis 06-489 isolated from infected human urinary tract by CLSI agar dilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis. |
| AID1778096 | Antibacterial activity against methicillin resistant Staphylococcus aureus assessed as bacterial growth inhibition after 18 hrs by broth microdilution method | |||
| AID660261 | Ratio of MIC for wild type Escherichia coli JC7623 to MIC for acrAB-deficient Escherichia coli JZM120 | 2012 | European journal of medicinal chemistry, Jun, Volume: 52 | Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics. |
| AID278550 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium breve R0070 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID533410 | Antimicrobial activity against Finegoldia magna by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID1079937 | Severe hepatitis, defined as possibly life-threatening liver failure or through clinical observations. Value is number of references indexed. [column 'MASS' in source] | |||
| AID1411627 | Bactericidal activity against Escherichia coli ATCC 35210 incubated for 24 hrs followed by serial sub-cultivation and measured after 24 hrs by microdilution method | |||
| AID519652 | Antimicrobial activity against Escherichia coli Irk1224 type 3 mutant harboring beta-lactamase CTX-M-3 Lys136 mutant gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID1204386 | Antibacterial activity against Escherichia coli assessed as growth inhibition at 100 umol/L after 8 hrs by ELISA plate reader analysis relative to control | 2015 | European journal of medicinal chemistry, Jun-05, Volume: 97 | Benzaldehyde Schiff bases regulation to the metabolism, hemolysis, and virulence genes expression in vitro and their structure-microbicidal activity relationship. |
| AID1693218 | Anti-infective activity against resistant Escherichia coli assessed as reduction in bacterial growth by microdilution method | 2021 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 32 | 2-Aryl-3-(6-trifluoromethoxy)benzo[d]thiazole-based thiazolidinone hybrids as potential anti-infective agents: Synthesis, biological evaluation and molecular docking studies. |
| AID424710 | Antibacterial activity against Staphylococcus aureus at 1 ug/disk | 2009 | Journal of natural products, Apr, Volume: 72, Issue:4 | Limazepines A-F, pyrrolo[1,4]benzodiazepine Antibiotics from an Indonesian Micrococcus sp. |
| AID529896 | Antimicrobial activity against Leptospira interrogans serovar Pomona isolate 4 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID562936 | Upregulation of cwp84 gene expression in Clostridium difficile 6425 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID530228 | Antimicrobial activity against Mycobacterium bovis BCG ML1060 carrying transposon IS1096::Km inserted at -206bp of fadD25/mmpL12 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID567763 | Antimicrobial activity against Bacillus subtilis ATCC 6638 after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID633859 | Antibacterial activity against Listeria monocytogenes NCTC 7973 incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID287371 | Antibacterial activity against Escherichia coli after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID324987 | Antibacterial activity against Haemophilus influenzae MSC06651 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID569256 | Antimycobacterial activity against Mycobacterium bovis BCG str. Tokyo 172 | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives. |
| AID530233 | Antimicrobial activity against Mycobacterium bovis BCG ML1005 carrying transposon IS1096::Km inserted at -76bp of mmpL8 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID585447 | Antimicrobial activity against ampG deficient Pseudomonas aeruginosa PAK harboring pZY0901 conferring resistance to gentamycin after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1287516 | Antibacterial activity against Bacillus subtilis NCIM 2079 after 12 hrs | 2016 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 26, Issue:7 | Synthesis, biological evaluation and molecular docking study of some novel indole and pyridine based 1,3,4-oxadiazole derivatives as potential antitubercular agents. |
| AID1193892 | Antimicrobial activity against Klebsiella pneumoniae MTCC 3384 assessed as zone of inhibition at 5 mg/ml after 24 hrs by agar well diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Rapid 'one-pot' synthesis of a novel benzimidazole-5-carboxylate and its hydrazone derivatives as potential anti-inflammatory and antimicrobial agents. |
| AID425602 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate LF82 in mouse J774A1 cells isolated from chronic ileal lesions of patient with Crohn's disease assessed as intracellular killing of bacteria at 10% compound Cmax after | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID547180 | Antibacterial activity against Vibrio alginolyticus assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID535187 | Antimicrobial activity against Clostridium glycolicum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID547186 | Antibacterial activity against Vibrio vulnificus assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1551860 | Antibacterial activity against Yersinia pseudotuberculosis | 2019 | European journal of medicinal chemistry, Jul-15, Volume: 174 | 1,2,4-Triazole-quinoline/quinolone hybrids as potential anti-bacterial agents. |
| AID623612 | Antibacterial activity against 10'8 CFU/mL Streptococcus pyogenes MTCC 442 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID334242 | Antimicrobial activity against Escherichia coli NCTC 9002 after 24 hrs by microdilution technique | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4 | Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline. |
| AID1079934 | Highest frequency of acute liver toxicity observed during clinical trials, expressed as a percentage. [column '% AIGUE' in source] | |||
| AID470060 | Antibacterial activity against Micrococcus luteus after 3 days by broth microdilution method | 2009 | Journal of natural products, Nov, Volume: 72, Issue:11 | Bioactive constituents of the stem bark of Mitrephora glabra. |
| AID497693 | Antimicrobial activity against colistin-susceptible Klebsiella pneumoniae isolated from bacteremia patient assessed as percentage of resistant isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea. |
| AID587733 | Ratio of Kcat to Km for Pseudomonas aeruginosa strain PS 297 metallo-beta-lactamase IMP-1 expressed in Escherichia coli BL21(DE3) assessed as substrate hydrolysis using 100 uM nitrocefin | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States. |
| AID1079944 | Benign tumor, proven histopathologically. Value is number of references indexed. [column 'T.BEN' in source] | |||
| AID334240 | Antimicrobial activity against Cladosporium herbarum after 10 days by microdilution technique | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4 | Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline. |
| AID1374421 | Antibacterial activity against Acinetobacter baumannii ATCC 02026 | 2018 | Bioorganic & medicinal chemistry letters, 03-01, Volume: 28, Issue:5 | Synthesis, antimicrobial activity and acid dissociation constants of methyl 5,5-diphenyl-1-(thiazol-2-yl)pyrrolidine-2-carboxylate derivatives. |
| AID546921 | Antibacterial activity against Escherichia coli by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID324984 | Antibacterial activity against Haemophilus influenzae MSC01363 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID740190 | Antibacterial activity against Pseudomonas aeruginosa NCIM 2036 by agar method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Microwave assisted nano (ZnO-TiO2) catalyzed synthesis of some new 4,5,6,7-tetrahydro-6-((5-substituted-1,3,4-oxadiazol-2-yl)methyl)thieno[2,3-c]pyridine as antimicrobial agents. |
| AID530209 | Antimicrobial activity against Mycobacterium bovis BCG ML1040 carrying transposon IS1096::Km inserted at +1930bp of papA2 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID548020 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237E mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID535694 | Antimicrobial activity against Azide-resistant Escherichia coli J53 transconjugant harboring Escherichia coli DH5alpha-5825 qnrB2 gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog. |
| AID532988 | Antibacterial activity against Klebsiella aerogenes NCIM 2281 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID565687 | Antimicrobial activity against beta-lactamase-positive ampicillin-resistant Haemophilus influenzae harboring fst1 mutant gene assessed as susceptible isolates by broth microdilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID395354 | Antibacterial activity against Bacillus cereus ATCC 7064 at 1 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID535748 | Antimicrobial activity against hospital-acquired Escherichia coli obtained from patient with intra-abdominal infection assessed as susceptible isolates by EUCAST method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Incidence and antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae with extended-spectrum beta-lactamases in community- and hospital-associated intra-abdominal infections in Europe: results of the 2008 Study for Monitoring Antimicrob |
| AID590506 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs | 2011 | European journal of medicinal chemistry, Apr, Volume: 46, Issue:4 | Synthesis, biopharmaceutical characterization, antimicrobial and antioxidant activities of 1-(4'-O-β-D-glucopyranosyloxy-2'-hydroxyphenyl)-3-aryl-propane-1,3-diones. |
| AID523273 | Antimicrobial activity against Escherichia coli HN1157/pHSG576oxa7 | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Kinetic parameters of efflux of penicillins by the multidrug efflux transporter AcrAB-TolC of Escherichia coli. |
| AID1585677 | Antibiofilm activity against methicillin-resistant Staphylococcus aureus planktonic biofilm assessed as optical density at 492 nm at MIC after 24 hrs by crystal violet staining-based UV-visible spectrophotometric analysis | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug resistance of bacterial infections. |
| AID521426 | Antibacterial activity against Stenotrophomonas maltophilia isolate KJ deficient in L1 beta lactamase gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Induction of L1 and L2 beta-lactamases of Stenotrophomonas maltophilia. |
| AID529616 | Antibacterial activity against Beta-lactamase positive Haemophilus influenzae assessed as susceptible isolates after 20 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID541148 | Antimicrobial activity against acrB::aph-deficient ciprofloxacin-resistant Salmonella enterica serovar enteritidis isolate 104-cip harboring gyrA D87Y,S83F mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID587977 | Antibacterial activity against Escherichia coli AS226 carrying pBSD-H2 after 18 hrs by broth microdilution method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID519632 | Activity of beta-lactamase FUS1 assessed as compound hydrolysis by spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442. |
| AID456088 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID1224741 | Antimicrobial activity against Vibrio cholerae MTCC 3906 by broth microdilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Ultrasound-assisted one-pot four-component synthesis of novel 2-amino-3-cyanopyridine derivatives bearing 5-imidazopyrazole scaffold and their biological broadcast. |
| AID425393 | Antibacterial activity against mucosa-associated Escherichia coli isolates isolated from patients with Crohn's disease by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID1104310 | Antibacterial activity against Salmonella enterica subsp. enterica serovar TyphimuriumATCC 13311 at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID584478 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN08 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID278259 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS9 tolC::Kan with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID467610 | Antibacterial activity against Escherichia coli by twofold serial broth dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new thiazole and thiophene derivatives. |
| AID603037 | Antimicrobial activity against Staphylococcus aureus at 1 ug/mL after 48 hrs by cup plate agar diffusion method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | Synthesis, antitumor and antimicrobial activities of 4-(4-chlorophenyl)-3-cyano-2-(β-O-glycosyloxy)-6-(thien-2-yl)-nicotinonitrile. |
| AID395356 | Antibacterial activity against Listeria monocytogenes ATCC 15313 at 1 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID1231417 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as growth inhibition at 20 ug after 24 hrs by disc agar diffusion method in presence of sulbactam | 2015 | Bioorganic & medicinal chemistry, Jul-01, Volume: 23, Issue:13 | Synthesis and biological evaluation of caracasine acid derivatives. |
| AID497694 | Antimicrobial activity against colistin-resistant Klebsiella pneumoniae isolated from bacteremia patient assessed as percentage of resistant isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea. |
| AID1104312 | Antibacterial activity against Escherichia coli ATCC 35210 at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID244857 | Minimal inhibitory concentration against Pseudomonas aeruginosa | 2004 | Bioorganic & medicinal chemistry letters, Dec-06, Volume: 14, Issue:23 | Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: a structure-activity evaluation study. |
| AID521966 | Antibacterial activity against Campylobacter jejuni assessed as resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID1256872 | Antibacterial activity against Bacillus subtilis after 48 hrs | 2015 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 25, Issue:22 | Synthesis and evaluation of antibacterial activity of (R)-2-methylheptyl isonicotinate, a putative naturally occurring bioactive agent. |
| AID1596677 | Bactericidal activity against Enterobacter cloacae incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID523267 | Activity at Escherichia coli HN1157 AmpC enzyme measured per mg of protein | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Kinetic parameters of efflux of penicillins by the multidrug efflux transporter AcrAB-TolC of Escherichia coli. |
| AID324179 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid vector at 1.5 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1774183 | Antibacterial activity against Enterococcus faecium DSM20477 assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID520388 | Ratio of Kcat to Km for Pseudomonas aeruginosa COL-1 metallo-beta lactamase VIM-2 | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain. |
| AID582923 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61A mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID422883 | Antimicrobial activity against 8 ug/ml colistin-subcultured Acinetobacter baumannii-Acinetobacter calcoaceticus complex isolated from diabetic patient with calcaneal osteomyelitis and bacteremia by broth microdilution assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Development of colistin-dependent Acinetobacter baumannii-Acinetobacter calcoaceticus complex. |
| AID561447 | Antibacterial activity against Escherichia coli DH10B harboring plasmid BCSK by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Reduced susceptibility to cefepime among Escherichia coli clinical isolates producing novel variants of CMY-2 beta-lactamase. |
| AID548002 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237N mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID573381 | Antibacterial activity against beta lactamase-negative Haemophilus influenzae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID545457 | Antimicrobial activity against Pseudomonas aeruginosa assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID1331871 | Antibacterial activity against methicillin-resistant Staphylococcus aureus | 2017 | Bioorganic & medicinal chemistry, 01-01, Volume: 25, Issue:1 | Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. |
| AID544287 | Antimicrobial activity against Enterococcus faecalis NKH17 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID532030 | Antimicrobial activity against Escherichia coli TOP10F' transformant harboring beta-lactamase CTX-M-78 by disk diffusion method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. |
| AID1767677 | Antibacterial activity against Shigella flexneri CCCD S006 assessed as inhibition of bacterial growth incubated for 24 hrs by microdilution assay | 2021 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 47 | Antimicrobial, modulatory, and antibiofilm activity of tt-farnesol on bacterial and fungal strains of importance to human health. |
| AID318662 | Antibacterial activity against Peptostreptococcus magnus GAI 5528 by broth microdilution method | 2008 | Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7 | Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens. |
| AID447590 | Antibacterial activity against Escherichia coli ATCC 8739 after 24 hrs by microtitration method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and antibacterial activity of 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-pyrazol-4-yl]-5-(substituted-phenyl)-[1,3,4]oxadiazoles. |
| AID519633 | Ratio of Kcat to Km for Brachyspira pilosicoli beta-lactamase OXA-63 expressed in Escherichia coli BL21 (DE3) assessed as compound hydrolysis by spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442. |
| AID585673 | Antimicrobial activity against ampG deficient Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID740189 | Antibacterial activity against Bacillus subtilis NCIM 2063 by agar method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Microwave assisted nano (ZnO-TiO2) catalyzed synthesis of some new 4,5,6,7-tetrahydro-6-((5-substituted-1,3,4-oxadiazol-2-yl)methyl)thieno[2,3-c]pyridine as antimicrobial agents. |
| AID1399261 | Antimicrobial activity against Enterobacter cloacae ATCC 13047 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID584773 | Antimicrobial activity against Acinetobacter lwoffii isolate L expressing beta-lactamase OXA-58 isolated from tracheal secretion of patient in presence of Sulbactam by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID563501 | Antimicrobial activity against cetylpyridinium chloride-resistant Serratia marcescens 01 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID547184 | Antibacterial activity against Vibrio fluvialis assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1180293 | Antimicrobial activity against Staphylococcus aureus NCIM-2901 after 20 hrs by two fold serial macrodilution technique | 2014 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15 | One pot three components microwave assisted and conventional synthesis of new 3-(4-chloro-2-hydroxyphenyl)-2-(substituted) thiazolidin-4-one as antimicrobial agents. |
| AID607165 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs by disc diffusion method | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14 | Exploration of antimicrobial and antioxidant potential of newly synthesized 2,3-disubstituted quinazoline-4(3H)-ones. |
| AID520712 | Antibacterial activity against Escherichia coli TOP10 harboring pOXA-58 in presence of 4 ug/ml clavulanic acid | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID1546102 | Antimicrobial activity against Klebsiella pneumoniae after 24 hrs by agar disk diffusion method | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID543419 | Antimicrobial activity against rifampicin-resistant Escherichia coli X1037 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime. |
| AID1774188 | Antibacterial activity against Escherichia coli delta cirA assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID544280 | Antimicrobial activity against Enterococcus faecalis NKH10 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID565626 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.12 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =793.3 +/- 42.40 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID562520 | Antimicrobial activity against vancomycin-, gentamicin-resistant Enterococcus faecium B expressing hylEfm gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Cotransfer of antibiotic resistance genes and a hylEfm-containing virulence plasmid in Enterococcus faecium. |
| AID1908117 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33592 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID512146 | Antibacterial activity against Escherichia coli MTCC 41 at 128 mg/ml after 16 hrs by disk diffusion test | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antiviral and antibacterial agents. |
| AID1412925 | Antibacterial activity against drug-resistant Escherichia coli by microdilution method | 2018 | MedChemComm, May-01, Volume: 9, Issue:5 | Design, synthesis and antimicrobial activity of usnic acid derivatives. |
| AID1527496 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus assessed as reduction in microbial growth after 24 to 48 hrs by microdilution susceptibility test | 2020 | European journal of medicinal chemistry, Jan-01, Volume: 185 | Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents. |
| AID278522 | Antimicrobial activity against Bifidobacterium bifidum R0071 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID306207 | Antimicrobial activity against Staphylococcus aureus | 2007 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 17, Issue:5 | Anti-mycobacterial activity of a bis-sulfonamide. |
| AID1306204 | Bactericidal activity against Escherichia coli ATCC 25922 after 18 hrs by microbroth dilution assay | 2016 | Bioorganic & medicinal chemistry, 07-15, Volume: 24, Issue:14 | The influence of halogen substituents on the biological properties of sulfur-containing flavonoids. |
| AID575419 | Antimicrobial activity against Listeria monocytogenes EGD-e assessed as growth inhibition after 16 hrs by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | The ABC transporter AnrAB contributes to the innate resistance of Listeria monocytogenes to nisin, bacitracin, and various beta-lactam antibiotics. |
| AID510166 | Antimicrobial activity against Escherichia coli ATCC 35218 by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID585400 | Ratio of Kcat to Km for Fluoribacter gormanii 1K07 metallo-beta-lactamase FEZ-1 | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides. |
| AID444057 | Fraction escaping hepatic elimination in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID1474166 | Liver toxicity in human assessed as induction of drug-induced liver injury by measuring severity class index | 2016 | Drug discovery today, Apr, Volume: 21, Issue:4 | DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. |
| AID151698 | In vitro antibacterial activity against SG 137 strain of Pseudomonas aeruginosa | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID725077 | Antimicrobial activity against Staphylococcus aureus after 12 to 18 hrs by micro-well dilution method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Synthesis and antibacterial and antifungal evaluation of some chalcone based sulfones and bisulfones. |
| AID300199 | Antibacterial activity against Staphylococcus aureus ATCC 25923 at 200 mg/mL after 24 hrs by disc diffusion method | 2007 | Bioorganic & medicinal chemistry, Aug-15, Volume: 15, Issue:16 | Identification of antibacterial and antiviral activities of novel fused 1,2,4-triazine esters. |
| AID1778093 | Antibacterial activity against Escherichia coli 25922 assessed as inhibition of bacterial growth incubated for 18 hrs by broth microdilution method | |||
| AID1168636 | Antimicrobial activity against Bacillus subtilis ATCC 6633 at 10 ug after 18 hrs by agar well diffusion assay | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Phosphorus-nitrogen compounds. Part 29. Syntheses, crystal structures, spectroscopic and stereogenic properties, electrochemical investigations, antituberculosis, antimicrobial and cytotoxic activities and DNA interactions of ansa-spiro-ansa cyclotetrapho |
| AID562474 | Antimicrobial activity against rifampicin-resistant Escherichia coli A15 transconjugant expressing beta-lactamase SHV-12 by Etest | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland. |
| AID1870137 | Antibacterial activity against wild type methicillin resistant Staphylococcus aureus 4561/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID1079940 | Granulomatous liver disease, proven histopathologically. Value is number of references indexed. [column 'GRAN' in source] | |||
| AID285689 | Antimicrobial susceptibility of carbapenem-resistant Pseudomonas aeruginosa PA4012 isolate expressing carbapenemase KPC2 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase. |
| AID544480 | Antibacterial activity against Escherichia coli K-12 W3110 infected in mouse assessed as reduction of bacterial level in blood at 30 ug, ip administered 15 mins and 12 hrs postinfection measured after 2 hrs post dose relative to control | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Variations in amino acid composition of antisense peptide-phosphorodiamidate morpholino oligomer affect potency against Escherichia coli in vitro and in vivo. |
| AID399615 | Antimicrobial activity against Escherichia coli ATCC 25922 at 0.1 mg/disk by disk diffusion assay | |||
| AID324309 | Antibacterial activity against Escherichia coli K12 mutant JHU313 assessed as cell count at 100 uM | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1916832 | Antibacterial activity against Staphylococcus aureus NCIM 2010 assessed as reduction in bacterial growth incubated for 8 hrs by absorbance based assay | 2022 | European journal of medicinal chemistry, Aug-05, Volume: 238 | Recent contribution of medicinally active 2-aminothiophenes: A privileged scaffold for drug discovery. |
| AID313670 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1 | Antimicrobial activities of the bromophenols from the red alga Odonthalia corymbifera and some synthetic derivatives. |
| AID1158652 | Antibacterial activity against Bacillus cereus grown in sheep blood agar media assessed as concentration required to inhibit bacterial growth due to absence of hemolysis of erythrocytes after 18 hrs by ten-fold broth dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Eremophilane-type sesquiterpenoids with diverse skeletons from Ligularia sagitta. |
| AID563500 | Antimicrobial activity against Serratia marcescens ATCC 13880 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID519636 | Activity of beta-lactamase FUS1 assessed as compound hydrolysis by spectrophotometry relative to benzyl-penicillin | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442. |
| AID340889 | Antimicrobial activity against Escherichia coli JM83 by serial dilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Cytoplasmic-membrane anchoring of a class A beta-lactamase and its capacity in manifesting antibiotic resistance. |
| AID562475 | Antimicrobial activity against rifampicin-resistant Escherichia coli A15 by Etest | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland. |
| AID1585652 | Antibacterial activity against methicillin-resistant Staphylococcus aureus after overnight incubation by micro broth dilution analysis | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug resistance of bacterial infections. |
| AID547171 | Antibacterial activity against Plesiomonas shigelloides assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID549334 | Antimicrobial activity against Escherichia coli isolate 100 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID565018 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1326369 | Antibacterial activity against Bacillus subtilis ATCC 47096 after 16 to 18 hrs by microbroth dilution assay | 2016 | Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24 | Biological characterization of the hygrobafilomycin antibiotic JBIR-100 and bioinformatic insights into the hygrolide family of natural products. |
| AID429366 | Antibacterial activity against Bacillus subtilis after 24 hrs by liquid dilution method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents. |
| AID584765 | Antimicrobial activity against Acinetobacter lwoffii isolate D expressing beta-lactamase OXA-164 isolated from tracheal secretion of patient in presence of Sulbactam by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID415328 | Antibacterial activity against multidrug-resistant vancomycin-intermediate Staphylococcus aureus VISA3 after 18 hrs by broth microdilution method | 2009 | Bioorganic & medicinal chemistry, Apr-15, Volume: 17, Issue:8 | Design, synthesis, antimicrobial activity and molecular modeling studies of novel benzofuroxan derivatives against Staphylococcus aureus. |
| AID630655 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus VISA3 after 18 hrs | 2011 | Bioorganic & medicinal chemistry, Nov-01, Volume: 19, Issue:21 | Synthesis, molecular modeling and preliminary biological evaluation of a set of 3-acetyl-2,5-disubstituted-2,3-dihydro-1,3,4-oxadiazole as potential antibacterial, anti-Trypanosoma cruzi and antifungal agents. |
| AID324976 | Antibacterial activity against Haemophilus influenzae MSC02070 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID289312 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 after 24 hrs | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18 | Synthesis and antimicrobial activity of some new thiazolyl thiazolidine-2,4-dione derivatives. |
| AID1139546 | Antibacterial activity against Escherichia coli DH5alpha expressing beta-lactamase OXA-58 by CLSI broth microdilution method | 2014 | Journal of medicinal chemistry, May-08, Volume: 57, Issue:9 | Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. |
| AID1328385 | Antibacterial activity against Staphylococcus aureus after 24 hrs by MTT based microdilution assay | 2016 | Journal of natural products, 09-23, Volume: 79, Issue:9 | Total Synthesis of (±)-Isoperbergins and Correction of the Chemical Structure of Perbergin. |
| AID565009 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1439802 | Antibacterial activity against Pseudomonas aeruginosa MTCC 102 at 100 ug incubated for 24 hrs under dark condition by agar well diffusion method | 2017 | Bioorganic & medicinal chemistry letters, 04-01, Volume: 27, Issue:7 | Biologically active perspective synthesis of heteroannulated 8-nitroquinolines with green chemistry approach. |
| AID207836 | Minimum inhibitory concentration against aerobic organism Staphylococcus aureus strain 2868 | 1982 | Journal of medicinal chemistry, Apr, Volume: 25, Issue:4 | Quaternary heterocyclylamino beta-lactams: a generic alternative to the classical acylamino side chain. |
| AID287373 | Antibacterial activity against Klebsiella pneumoniae after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID557688 | Antimicrobial activity in Prevotella veroralis by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID535645 | Antimicrobial activity against Group B Streptococcus serotype Ia N1 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID206072 | In vitro inhibitory activity against Streptococci EryRi (98);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID555233 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 20 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID556561 | Antimicrobial activity against sodB gene-deficient Escherichia coli K-12 DKsodB by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID582968 | Antimicrobial activity against beta-lactamase A and B-deficient Yersinia enterocolitica GY5718 after 20 hrs by Etest | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Contribution of BlaA and BlaB beta-lactamases to antibiotic susceptibility of Yersinia enterocolitica biovar 1B. |
| AID510173 | Antimicrobial activity against ceftriaxone-resistant Bacillus subtilis by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID495335 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with Asp350Asn, Ser357Asp, Ser385Thr, Leu389Phe, Ala502Thr, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID556756 | Bactericidal activity against ahpC gene-deficient Escherichia coli K-12 3200 after 18 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID373332 | Antibacterial activity against Micrococcus luteus ATCC 10240 at 10 ug/disk after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID558328 | Antibacterial activity against bla gene-positive and nitrocefin reaction-positive beta-lactamase harboring Campylobacter jejuni isolate P286 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID1139542 | Antibacterial activity against Escherichia coli DH5alpha expressing beta-lactamase CTX-M-15 by CLSI broth microdilution method | 2014 | Journal of medicinal chemistry, May-08, Volume: 57, Issue:9 | Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. |
| AID1501240 | Antibacterial activity against Enterococcus faecalis ATCC 29212 measured after overnight incubation | 2017 | Journal of natural products, 09-22, Volume: 80, Issue:9 | Thermoactinoamide A, an Antibiotic Lipophilic Cyclopeptide from the Icelandic Thermophilic Bacterium Thermoactinomyces vulgaris. |
| AID304971 | Antibacterial activity against Staphylococcus aureus by broth micro-dilution technique | 2007 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1 | New antifungal flavonoid glycoside from Vitex negundo. |
| AID559328 | Antimicrobial activity against Salmonella enterica serovar Typhimurium assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID775960 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as growth inhibition at 100 ug/mL after 18 to 24 hrs by microdilution assay | 2013 | European journal of medicinal chemistry, Nov, Volume: 69 | Synthesis, antibacterial and antioxidant activities of new 1-alkyl-4-(1-alkyl-4-oxo-1,4-dihydroquinolin-2-yl)pyridinium bromides. |
| AID164574 | The compound was tested for minimal inhibitory concentration against Resistant Pseudomonas aeruginosa | 2002 | Bioorganic & medicinal chemistry letters, Sep-02, Volume: 12, Issue:17 | The activity of p-methoxybenzylisothiocyanate against Neisseria gonorrhoeae, Haemophilus ducreyi, and other microorganisms. |
| AID548257 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm, graRm mutant gene after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID573354 | Antibacterial activity against ceftazidime-susceptible Escherichia coli assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID555209 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 90 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID565061 | Antibacterial activity against wild-type Escherichia coli AG100 at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID1585551 | Antibacterial activity against Proteus vulgaris after 24 hrs | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Benzofuran derivatives and their anti-tubercular, anti-bacterial activities. |
| AID1104319 | Antibacterial activity against Proteus mirabilis at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID523271 | Lipophilicity, log P of the compound | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Kinetic parameters of efflux of penicillins by the multidrug efflux transporter AcrAB-TolC of Escherichia coli. |
| AID568335 | Antimicrobial activity against ESBL producing Klebsiella pneumoniae by broth dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 21, Issue:4 | Design and synthesis of potent Gram-negative specific LpxC inhibitors. |
| AID530235 | Antimicrobial activity against Mycobacterium bovis BCG ML1034 by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID684948 | Antibacterial activity against Pseudomonas aeruginosa ATCC BAA-427 after 24 hrs by broth microdilution method | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Micelles catalyzed chemo- and regio-selective one pot and one step synthesis of 2,3,5,6-tetrakis(alkyl and arylsulfanyl)-1,4-benzoquinones and 2,5-diaminosubstituted-1,4-benzoquinones "In-Water" and their biological evaluation as antibacterial and antifun |
| AID644241 | Antibacterial activity against Streptococcus pneumoniae clinical isolate after 16 to 20 hrs by two fold agar dilution method | 2012 | European journal of medicinal chemistry, Mar, Volume: 49 | Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2. |
| AID1060497 | Antibacterial activity against Bacillus cereus MTCC 619 by agar streak dilution method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Access to a new class of biologically active quinoline based 1,2,4-triazoles. |
| AID1105382 | Antibacterial activity against Xanthomonas oryzae ITCC B-47 assessed as as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID1243994 | Antimicrobial activity against Aeromonas hydrophila by agar dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | Design and synthesis of some new pyrazolyl-pyrazolines as potential anti-inflammatory, analgesic and antibacterial agents. |
| AID1484007 | Antimicrobial activity against Escherichia coli JM109 assessed as growth inhibition zone after 18 hrs by disc diffusion method | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2 | Discovery of C-Glycosylpyranonaphthoquinones in Streptomyces sp. MBT76 by a Combined NMR-Based Metabolomics and Bioinformatics Workflow. |
| AID294831 | Antibacterial activity against Staphylococcus epidermidis after 24 hrs by microdilution broth method | 2007 | Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8 | Identification of antitumour activity of novel derivatives of 8-aryl-2,6,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazine-3,4-dione and 8-aryl-4-imino-2,3,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazin-3(6H)-one. |
| AID494534 | Antimicrobial activity against Pseudomonas aeruginosa NCIM 5029 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID494534 | Antimicrobial activity against Pseudomonas aeruginosa NCIM 5029 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May-06 | Synthesis, antibacterial activity evaluation and QSAR studies of novel dispiropyrrolidines. |
| AID555455 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 52 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1224738 | Antimicrobial activity against Clostridium tetani MTCC 449 by broth microdilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Ultrasound-assisted one-pot four-component synthesis of novel 2-amino-3-cyanopyridine derivatives bearing 5-imidazopyrazole scaffold and their biological broadcast. |
| AID519112 | Antibacterial activity against Proteus mirabilis M 19 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID1382080 | Antibacterial activity against Yersinia pseudotuberculosis ATCC 911 after 18 to 24 hrs by double microdilution method | 2018 | European journal of medicinal chemistry, Feb-25, Volume: 146 | Ciprofloxacin derivatives and their antibacterial activities. |
| AID558330 | Antibacterial activity against bla gene-positive and nitrocefin reaction-positive beta-lactamase harboring Campylobacter jejuni isolate P316 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID1334269 | Antibacterial activity against Bacillus subtilis | 2017 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 27, Issue:2 | New bithiazolyl hydrazones: Novel synthesis, characterization and antitubercular evaluation. |
| AID567283 | Ratio of Kcat to Km for Acinetobacter baumannii ADC-33 beta-lactamase to Kcat to Km for Acinetobacter baumannii ADC-11 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Extended-spectrum cephalosporinase in Acinetobacter baumannii. |
| AID1388196 | Antibacterial activity against Bacillus subtilis MTCC 10619 at 100 ug/ml incubated for 12 hrs by agar disc diffusion assay | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18 | Synthesis, antimicrobial activity, structure-activity relationship and cytotoxic studies of a new series of functionalized (Z)-3-(2-oxo-2-substituted ethylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ones. |
| AID644169 | Antibacterial activity against Enterobacter cloacae human isolate after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID718921 | Antimicrobial activity against Streptococcus pneumoniae by microplate reader analysis | 2012 | Bioorganic & medicinal chemistry, Dec-15, Volume: 20, Issue:24 | Purpuroines A-J, halogenated alkaloids from the sponge Iotrochota purpurea with antibiotic activity and regulation of tyrosine kinases. |
| AID352581 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 at 10 ug after 18 hrs by agar-well diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Synthesis of some new 1,2,4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities. |
| AID568331 | Antimicrobial activity against ESBL producing Escherichia coli by broth dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 21, Issue:4 | Design and synthesis of potent Gram-negative specific LpxC inhibitors. |
| AID278268 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS38 with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID420225 | Antimicrobial activity against multidrug-resistant Enterococcus faecalis H.C. 21944 isolate after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID1226730 | Antimicrobial activity against Escherichia coli MG1655 incubated at 37 degC overnight for 18 hrs | 2015 | ACS medicinal chemistry letters, Apr-09, Volume: 6, Issue:4 | Membrane-Targeting DCAP Analogues with Broad-Spectrum Antibiotic Activity against Pathogenic Bacteria. |
| AID1471035 | Growth inhibition of Escherichia coli NCIM 2576 at 1 ug/ml measured after 8 hrs relative to control | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID1585544 | Antibacterial activity against Staphylococcus aureus assessed as zone of inhibition at 1 mg/ml after 32 hrs by agar-well diffusion method | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Benzofuran derivatives and their anti-tubercular, anti-bacterial activities. |
| AID313667 | Antibacterial activity against Micrococcus luteus IFC 12708 after 24 hrs | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1 | Antimicrobial activities of the bromophenols from the red alga Odonthalia corymbifera and some synthetic derivatives. |
| AID1388186 | Antibacterial activity against Streptomyces griseus MTCC 4734 incubated for 24 hrs by serial dilution method | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18 | Synthesis, antimicrobial activity, structure-activity relationship and cytotoxic studies of a new series of functionalized (Z)-3-(2-oxo-2-substituted ethylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ones. |
| AID1331877 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 | 2017 | Bioorganic & medicinal chemistry, 01-01, Volume: 25, Issue:1 | Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. |
| AID369631 | Antimicrobial activity against beta-lactamase positive ampicillin-resistant Haemophilus influenzae by E-test | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Can the Etest correctly determine the MICs of beta-lactam and cephalosporin antibiotics for beta-lactamase-negative ampicillin-resistant Haemophilus influenzae? |
| AID535669 | Antimicrobial activity against beta-lactamase positive, ampicillin-clavulanic acid resistant Haemophilus influenzae expressing fst1 mutant gene by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Genotypic versus phenotypic characterization, with respect to beta-lactam susceptibility, of Haemophilus influenzae isolates exhibiting decreased susceptibility to beta-lactam resistance markers. |
| AID633854 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID534380 | Antibacterial activity against Citrobacter freundii KHM243 clinical isolate by microdilution method in presence of Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate. |
| AID648411 | Antibacterial activity against recultured Klebsiella pneumoniae at MIC after 3 to 4 days by disc diffusion method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Facile synthesis, characterization and pharmacological activities of 3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 5,6-dihydro-3,6-disubstituted-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles. |
| AID1399500 | Bactericidal activity against Enterobacter cloacae by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID547802 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237W mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID324998 | Antibacterial activity against Haemophilus parahaemolyticus ATCC 10014 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID557748 | Antimicrobial activity in Anaerococcus prevotii by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1399277 | Antimicrobial activity against Escherichia coli isolate SJ 5 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID546971 | Antibacterial activity against Aeromonas caviae assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID285690 | Antimicrobial susceptibility of carbapenem-resistant Pseudomonas aeruginosa PA4036 isolate expressing carbapenemase KPC2 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase. |
| AID575416 | Antimicrobial activity against anrB-deficient Listeria monocytogenes EGD-e at 10 ug after 16 hrs by disk diffusion assay | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | The ABC transporter AnrAB contributes to the innate resistance of Listeria monocytogenes to nisin, bacitracin, and various beta-lactam antibiotics. |
| AID555466 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 69 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID324208 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 assessed as cell count in log phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID555483 | Ratio of MIC for Acinetobacter genomosp. 3 isolate 103 to MIC for Acinetobacter genomosp. 3 isolate 103 in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID758270 | Antibacterial activity against Pseudomonas aeruginosa MTCC 1688 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Design and synthesis of biquinolone-isoniazid hybrids as a new class of antitubercular and antimicrobial agents. |
| AID584292 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus fleurettii SFMP02 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID542772 | Antimicrobial activity against Escherichia coli J53 transformed with pHNDU1 carrying qnrB6 gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID587728 | Antimicrobial activity against Escherichia coli DH5alpha carrying Pseudomonas aeruginosa strain PS 297 IMP-1-pLBII after 18 hrs by microdilution broth method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States. |
| AID74714 | Inhibition of gram positive bacteria growth. | 1989 | Journal of medicinal chemistry, Jun, Volume: 32, Issue:6 | Synthesis and antimicrobial properties of substituted beta-aminoxypropionyl penicillins and cephalosporins. |
| AID520714 | Antibacterial activity against Escherichia coli TOP10 harboring pOXA-97 in presence of 4 ug/ml clavulanic acid | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID693577 | Antibacterial activity against Escherichia coli MTCC 4351 after 24 hrs by tube dilution method | 2012 | European journal of medicinal chemistry, Dec, Volume: 58 | Synthesis pharmacological evaluation and docking studies of pyrimidine derivatives. |
| AID1423469 | Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured MDH refolding after 20 to 40 mins by spectrometric analysis | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID559904 | Antimicrobial activity against Escherichia coli TF-KP278 harboring beta-lactamase OXY-1 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | First detection of plasmid-encoded blaOXY beta-lactamase. |
| AID1527479 | Antimicrobial activity against Staphylococcus aureus ATCC 19433 assessed as reduction in microbial growth after 24 to 48 hrs by microdilution susceptibility test | 2020 | European journal of medicinal chemistry, Jan-01, Volume: 185 | Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents. |
| AID546929 | Antibacterial activity against Salmonella enterica serovar Enteritidis assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID547779 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237G mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID285202 | Antimicrobial activity against Escherichia coli M114 mutant with AG100 lon4::IS186 marR::IS2 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID565230 | Antimicrobial activity against Mycobacterium chelonae 9917 by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID436783 | Antifungal activity against Aspergillus ochraceus Wilhelm AUCC 230 at 25 ug/mL after 24 hrs by agar diffusion assay | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10 | Synthesis, characterization and in vitro antimicrobial activity of novel 2-thioxo-4-thiazolidinones and 4,4'-bis(2-thioxo-4-thiazolidinone-3-yl)diphenylsulfones. |
| AID465614 | Antibacterial activity against Proteus vulgaris ATCC 3851 | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Discorhabdins from the Korean marine sponge Sceptrella sp. |
| AID448149 | Antimicrobial activity against Yersinia pseudotuberculosis ATCC 911 at 10 ug after 18 hrs by well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis of some new 1,2,4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities. |
| AID556567 | Antimicrobial activity against katG,katE gene-deficient Escherichia coli K-12 3201 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID559902 | Antimicrobial activity against Escherichia coli TF-KO279 harboring beta-lactamase OXY-1 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | First detection of plasmid-encoded blaOXY beta-lactamase. |
| AID1694051 | Antibacterial activity against Bacillus cereus UW85 assessed as diameter of zone inhibition at 5 mg/ml incubated for 24 hrs by agar plate diffusion method | 2021 | Bioorganic & medicinal chemistry, 02-01, Volume: 31 | Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study. |
| AID324243 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoU mutant assessed as cell count in stationary phase at 100 ug/ml after 10 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID442424 | Antimicrobial activity against Bacillus cereus after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID422496 | Activity of Carnobacterium divergens BM4489 penicillinase Cad-1 assessed as initial rate of hydrolysis by spectrophotometer | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens. |
| AID582912 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61C mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID551087 | Antibacterial activity against Klebsiella pneumoniae at 1000 ug/mL after 72 hrs by agar diffusion assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1 | 3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents. |
| AID113444 | Antibacterial activity was determined against Streptococcus pneumoniae C 0096 at a challenge dose of 1.60*10e2 (cells/mouse) administered subcutaneously | 1995 | Journal of medicinal chemistry, Jun-09, Volume: 38, Issue:12 | Synthesis and biological evaluation of a series of new parenteral optically active 3-[[(N-alkylpyridinium-4'-yl)thio]methyl]-2-oxaisocephems. |
| AID1337848 | Antifungal activity against Cryptococcus neoformans NCIM 576 by standard agar method | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Quinolidene-rhodanine conjugates: Facile synthesis and biological evaluation. |
| AID287375 | Antibacterial activity against Micrococcus luteus after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID565440 | Antimicrobial activity against Streptococcus intermedius SI006 biofilm harboring luxS mutant gene assessed as biofilm bacterial count at 0.06 ug/ml (Rvb =310.8 +/- 17.10 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID526304 | Antimicrobial activity against Escherichia coli by agar plate disk diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Bernthsen synthesis, antimicrobial activities and cytotoxicity of acridine derivatives. |
| AID563502 | Antimicrobial activity against cetylpyridinium chloride-sensitive Serratia marcescens 71 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID545143 | Ratio of Kcat to Km for Klebsiella pneumoniae cephalosporinase CMY-36 by spectrophotometry | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids. |
| AID567281 | Ratio of Kcat to Km for Acinetobacter baumannii ADC-33 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Extended-spectrum cephalosporinase in Acinetobacter baumannii. |
| AID1908116 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID575339 | Antimicrobial activity against Listeria monocytogenes EGD-e at 10 ug after 16 hrs by disk diffusion assay | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | The ABC transporter AnrAB contributes to the innate resistance of Listeria monocytogenes to nisin, bacitracin, and various beta-lactam antibiotics. |
| AID587729 | Antimicrobial activity against Escherichia coli DH5alpha carrying empty pBC-SK after 18 hrs by microdilution broth method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States. |
| AID456075 | Antibacterial activity against Bacillus cereus clinical isolate after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID436777 | Antibacterial activity against Serratia marcescens IMRU 70 at 25 ug/mL after 24 hrs by agar diffusion assay | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10 | Synthesis, characterization and in vitro antimicrobial activity of novel 2-thioxo-4-thiazolidinones and 4,4'-bis(2-thioxo-4-thiazolidinone-3-yl)diphenylsulfones. |
| AID529622 | Antibacterial activity against Beta-lactamase negative Haemophilus influenzae harboring fst1 mutant gene assessed as susceptible isolates after 20 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID456081 | Antibacterial activity against Escherichia coli ATCC 35210 after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID294415 | Antimicrobial activity against Escherichia coli at 25 ug/mL by agar diffusion technique | 2007 | European journal of medicinal chemistry, Jul, Volume: 42, Issue:7 | Synthesis and antimicrobial evaluation of some new thiazole, thiazolidinone and thiazoline derivatives starting from 1-chloro-3,4-dihydronaphthalene-2-carboxaldehyde. |
| AID543102 | Antimicrobial activity against Pseudomonas lini isolate C701 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID548016 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237D mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID527632 | Antimicrobial activity against Proteus vulgaris ATCC 3851 after 24 hrs by broth dilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Bromophenols as Candida albicans isocitrate lyase inhibitors. |
| AID648406 | Antibacterial activity against Escherichia coli ATTC 25922 after 16 to 18 hrs by serial dilution method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Facile synthesis, characterization and pharmacological activities of 3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 5,6-dihydro-3,6-disubstituted-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles. |
| AID419333 | Antibacterial activity against Bacillus subtilis MTCC 121 after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis and evaluation of some new benzimidazole derivatives as potential antimicrobial agents. |
| AID1204968 | Antimicrobial activity against Salmonella enterica ATCC 14028 after 24 hrs by twofold dilution method | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Additional sesterterpenes and a nortriterpene saponin from the sponge Clathria gombawuiensis. |
| AID1299579 | Antibacterial activity against Staphylococcus aureus RN4220 ATCC 35556 incubated overnight by microbroth dilution method | 2016 | Journal of medicinal chemistry, Apr-14, Volume: 59, Issue:7 | Antibacterial Diamines Targeting Bacterial Membranes. |
| AID1471044 | Growth inhibition of Bacillus subtilis NCIM 2162 at 1 ug/ml measured after 12 hrs relative to control | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID535639 | Antimicrobial activity against Group B streptococcus serotype VI R1 harboring F395L, V405A, R433H, H438Y, and G648A mutations in PBP 2X and T567I mutation in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID763995 | Antibacterial activity against Staphylococcus aureus ATCC 6538P after 24 hrs by two-fold serial dilution method | 2013 | European journal of medicinal chemistry, Aug, Volume: 66 | Synthesis, biological evaluation and molecular docking studies of some pyrimidine derivatives. |
| AID1695925 | Antibacterial activity against Bacillus subtilis ATCC 6633 incubated for 24 hrs by broth dilution method | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID1264894 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 9721 for 17 to 48 hrs by MTT assay | 2015 | Journal of natural products, Nov-25, Volume: 78, Issue:11 | Identification of Elaiophylin Skeletal Variants from the Indonesian Streptomyces sp. ICBB 9297. |
| AID1104318 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID255563 | Antibacterial activity against Staphylococcus aureus (ATCC 25923)i at concentration 32.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID521425 | Antibacterial activity against Stenotrophomonas maltophilia isolate KJ by Etest | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Induction of L1 and L2 beta-lactamases of Stenotrophomonas maltophilia. |
| AID463402 | Antimicrobial activity against Staphylococcus aureus at 1000 ug after 24 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines. |
| AID1368637 | Anti-biofilm activity against Paracoccus sp. 4M6 assessed as inhibition of bacterial adhesion incubated for 15 hrs at 20 degC by Syto 61 dye based fluorimetric assay | 2018 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 28, Issue:2 | Towards smart biocide-free anti-biofilm strategies: Click-based synthesis of cinnamide analogues as anti-biofilm compounds against marine bacteria. |
| AID1399268 | Antimicrobial activity against Klebsiella pneumoniae isolate SJ 1 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID508591 | Antibacterial activity against wild type Salmonella enteritidis 104 harboring gyrA D87Y mutant gene by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Fitness costs and stability of a high-level ciprofloxacin resistance phenotype in Salmonella enterica serotype enteritidis: reduced infectivity associated with decreased expression of Salmonella pathogenicity island 1 genes. |
| AID585863 | Antimicrobial activity against Pseudomonas aeruginosa isolate 12 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1694056 | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as reduction in bacterial growth incubated for 18 hrs by two-fold serial dilution method | 2021 | Bioorganic & medicinal chemistry, 02-01, Volume: 31 | Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study. |
| AID269642 | Antibacterial activity against Bacillus subtilis ATCC 6633 | 2006 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 16, Issue:16 | Lactones from a brown alga endophytic fungus (No. ZZF36) from the South China Sea and their antimicrobial activities. |
| AID509632 | Antimicrobial activity against Staphylococcus aureus 25 transformant carrying plasmid pKKS25 and expressing erm(T), dfrKtet(L), tet(K), tet(M), mecA and blaZ genes by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID1076002 | Antibacterial activity against Escherichia coli NCIM 2256 by standard agar method | 2014 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 24, Issue:6 | Synthesis, antileishmanial activity and docking study of N'-substitutedbenzylidene-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetohydrazides. |
| AID278523 | Antimicrobial activity against Bifidobacterium bifidum ATCC 15696 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID549012 | Antimicrobial activity against Vancomycin-nonsusceptible Enterococcus faecalis assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID66412 | In vitro inhibitory activity against enterococci EryRi (19);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID770916 | Antibacterial activity against Bacillus subtilis IFO 3007 after 24 hrs by two fold dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID201428 | In vitro antibacterial activity against SG 511 strain of Staphylococcus aureus | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID285691 | Antimicrobial susceptibility of Citrobacter freundii CF6010 isolate expressing carbapenemase KPC2 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase. |
| AID644167 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID555239 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 21 by Etest method in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID278261 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS14 gyrA+ with GyrA D87G mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1744566 | Inhibition of Staphylococcus aureus FabH A81V mutant assessed as bacterial growth inhibition measured after 18 hrs by resazurin dye based broth dilution assay | 2021 | ACS medicinal chemistry letters, Mar-11, Volume: 12, Issue:3 | Semisynthesis and Biological Evaluation of Platencin Thioether Derivatives: Dual FabF and FabH Inhibitors against MRSA. |
| AID1695788 | Antibacterial activity against Bacillus cereus RCMB-010067 assessed as diameter of inhibition zone at 5 mg/ml by diffusion technique | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID640578 | Antibacterial activity against Proteus vulgaris ATCC 3851 | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2 | Bioactive lipids from the sponge Spirastrella abata. |
| AID529593 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-1 assessed as bacterial density at 2048 ug/ml after 18 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID313669 | Antibacterial activity against Salmonella Typhimurium ATCC 14028 after 24 hrs | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1 | Antimicrobial activities of the bromophenols from the red alga Odonthalia corymbifera and some synthetic derivatives. |
| AID1399492 | Bactericidal activity against Bacillus cereus by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID546973 | Antibacterial activity against Aeromonas sobria assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID289241 | Antimicrobial activity against Escherichia coli | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18 | Utility of 6-amino-2-thiouracil as a precursor for the synthesis of bioactive pyrimidine derivatives. |
| AID1265199 | Bactericidal activity against Escherichia coli ATCC 8739 after 24 hrs | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes. |
| AID519118 | Antibacterial activity against Proteus mirabilis M 31 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID1159094 | Antimicrobial activity against Salmonella typhimurium ATCC 14028 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID285337 | Antimicrobial activity against Escherichia coli qnrA1 producing urinary specimen isolate 13.52 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First report of plasmid-mediated qnrA1 in a ciprofloxacin-resistant Escherichia coli strain in Latin America. |
| AID405082 | Antimicrobial activity against Escherichia coli 33587-TC9 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Biochemical characterization of PER-2 and genetic environment of blaPER-2. |
| AID1364563 | Antimicrobial activity against methicillin-sensitive Staphylococcus aureus incubated for 20 hrs by CLSI protocol based method | 2017 | Journal of natural products, 04-28, Volume: 80, Issue:4 | Identification of Pyridinium with Three Indole Moieties as an Antimicrobial Agent. |
| AID1127990 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by microdilution method | 2014 | Journal of medicinal chemistry, Mar-27, Volume: 57, Issue:6 | First identification of boronic species as novel potential inhibitors of the Staphylococcus aureus NorA efflux pump. |
| AID1877436 | Antibacterial activity against Bacillus cereus | 2022 | Bioorganic & medicinal chemistry letters, 01-01, Volume: 55 | New bis- and tetrakis-1,2,3-triazole derivatives: Synthesis, DNA cleavage, molecular docking, antimicrobial, antioxidant activity and acid dissociation constants. |
| AID478780 | Antibacterial activity against Escherichia coli ATCC 4230 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5 | Synthesis, spectroscopic and biological studies on the new symmetric Schiff base derived from 2,6-diformyl-4-methylphenol with N-aminopyrimidine. |
| AID595278 | Antimicrobial activity against Candida albicans at 1 mg/ml after 48 hrs by agar well diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Applications of 2-arylhydrazononitriles in synthesis: preparation of new indole containing 1,2,3-triazole, pyrazole and pyrazolo[1,5-a]pyrimidine derivatives and evaluation of their antimicrobial activities. |
| AID625285 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic necrosis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID770910 | Antibacterial activity against Escherichia coli IFO 3301 after 24 hrs by two fold dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID573360 | Antibacterial activity against ceftazidime-susceptible Klebsiella pneumoniae assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID419336 | Antibacterial activity against Escherichia coli ATCC 25922 at 100 ug/ml after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis and evaluation of some new benzimidazole derivatives as potential antimicrobial agents. |
| AID1695927 | Antibacterial activity against Staphylococcus aureus ATCC 6538p incubated for 24 hrs by broth dilution method | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID544531 | Antimicrobial activity against Escherichia coli DH5[alpha] isolate GC 7668 expressing bla SHV-48 gene by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Pyrosequencing using the single-nucleotide polymorphism protocol for rapid determination of TEM- and SHV-type extended-spectrum beta-lactamases in clinical isolates and identification of the novel beta-lactamase genes blaSHV-48, blaSHV-105, and blaTEM-155 |
| AID1491340 | Antibacterial activity against Bacillus cereus UW 85 after 24 hrs by two-fold serial dilution method | 2017 | European journal of medicinal chemistry, Sep-08, Volume: 137 | Synthesis, antimicrobial, antiquorum-sensing and antitumor activities of new benzimidazole analogs. |
| AID1334266 | Antibacterial activity against Escherichia coli | 2017 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 27, Issue:2 | New bithiazolyl hydrazones: Novel synthesis, characterization and antitubercular evaluation. |
| AID360052 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as lactoyl tripeptide level | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID519108 | Antibacterial activity against Proteus mirabilis M 44 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID447063 | Antibacterial activity against Staphylococcus aureus ATCC 6538 at 10 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID1306201 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs by microbroth dilution assay | 2016 | Bioorganic & medicinal chemistry, 07-15, Volume: 24, Issue:14 | The influence of halogen substituents on the biological properties of sulfur-containing flavonoids. |
| AID283559 | Antibacterial activity against Escherichia coli AG102MB after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Substrate competition studies using whole-cell accumulation assays with the major tripartite multidrug efflux pumps of Escherichia coli. |
| AID564895 | Antibacterial activity against wild-type Escherichia coli AG100 harboring IS186 insertion in lon3 gene and Tn5 insertion in ycgE gene at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID278524 | Antimicrobial activity against Bifidobacterium bifidum BB12 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID532990 | Antibacterial activity against Klebsiella pneumoniae NCIM 2883 assessed as growth inhibition in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID1104315 | Antibacterial activity against clinical isolate Bacillus cereus at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID584479 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN09 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID1728307 | Antifungal activity against Candida albicans ATCC 90028 assessed as diameter of inhibition zone at 10 mg/ml by disk diffusion assay | 2021 | European journal of medicinal chemistry, Jan-15, Volume: 210 | Preparation of new 1,3-dibenzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. |
| AID278240 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-3 with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID573365 | Antibacterial activity against ceftazidime-susceptible Morganella morganii assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID548484 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm mutant gene after 48 hrs by Etest in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID555227 | Activity of Acinetobacter genomosp. 3 isolate 195 ADC-18 | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID555479 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 14 by Etest method in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID577203 | Antimicrobial activity against Escherichia coli O157:H7 PT-40 in logarithmic phase encoding Stx-2 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID529893 | Antimicrobial activity against Leptospira interrogans serovar Bataviae isolate 1 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID66409 | In vitro inhibitory activity against enterococci EryRc (13);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID442420 | Antimicrobial activity against Pseudomonas aeruginosa at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID587972 | Ratio of Kcat to Km for Escherichia coli beta-lactamase Toho-1 D240S mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID770920 | Antibacterial activity against Staphylococcus aureus IFO 3060 assessed as growth inhibition at 100 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID1868098 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 assessed as inhibition of visible bacterial growth incubated for 18 hrs by CLSI protocol based assay | 2022 | Journal of natural products, 05-27, Volume: 85, Issue:5 | Enceleamycins A-C, Furo-Naphthoquinones from |
| AID405825 | Antimicrobial activity against Acinetobacter baumannii 694 isolate harboring bla IMP-1 carrying integron In86 containing aminoglycoside resistance gene aac(6')-3 | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital. |
| AID736388 | Antimicrobial activity against Bacillus subtilis at 1 mg/mL after 24 hrs by agar disc diffusion method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Synthesis and antimicrobial activity of some new benzo and naphthonitrile derivatives. |
| AID565228 | Antimicrobial activity against Mycobacterium chelonae ATCC 35752 by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID770907 | Antibacterial activity against Pseudomonas aeruginosa IFO 3448 after 24 hrs by two fold dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID1183260 | Antimicrobial activity against Vibrio cholerae MTCC 3906 assessed as absence of visible growth after 24 to 48 hrs by broth micro dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis and characterization of fluoro substituted novel pyrazolylpyrazolines scaffold and their pharmacological screening. |
| AID383175 | Antimicrobial activity against Escherichia coli ATCC 11775 | 2008 | Journal of natural products, Apr, Volume: 71, Issue:4 | Sesterterpenoids from the sponge Sarcotragus sp. |
| AID1594843 | Antibacterial activity against Escherichia coli ATCC 35210 by microdilution method | 2019 | Journal of natural products, 06-28, Volume: 82, Issue:6 | Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. |
| AID520868 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus saprophyticus isolate TSU28 isolated from genitourinary tracts of acute cystitis patient after 24 hrs at 35 degC by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Methicillin-resistant Staphylococcus saprophyticus isolates carrying staphylococcal cassette chromosome mec have emerged in urogenital tract infections. |
| AID1399255 | Antimicrobial activity against Enterococcus faecalis ATCC 33186 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID1290442 | Antibacterial activity against Salmonella typhi MTCC 98 after 24 to 48 hrs by broth microdilution method | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities. |
| AID547774 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237A mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID583097 | Antimicrobial activity against Escherichia coli XL1-Blue harboring pLBII-VIM-2 plasmid expressing VIM-2 A64W mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1399264 | Antimicrobial activity against Klebsiella pneumoniae ATCC 33495 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID278535 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium bifidum R0071 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1329753 | Antibacterial activity against Propionibacterium acnes ATCC 6919 after 24 hrs by broth microdilution method | |||
| AID420226 | Antimicrobial activity against multidrug-resistant Enterococcus faecalis H.C. 24708 isolate after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID535633 | Antimicrobial activity against Group B streptococcus serotype Ia R7 harboring T77I, F395V and S353F in PBP 2X; V80A and G613R in PBP 2B; and L45P, N163K, N723S and Y470F in PBP 1A by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID530211 | Antimicrobial activity against Mycobacterium bovis BCG ML1069 carrying transposon IS1096::Km inserted at +205bp of gmhA gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID588213 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID564826 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1462721 | Antimicrobial activity against Streptococcus pyogenes MTCC 442 | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20 | Benzothiazole analogues: Synthesis, characterization, MO calculations with PM6 and DFT, in silico studies and in vitro antimalarial as DHFR inhibitors and antimicrobial activities. |
| AID1762807 | Antibacterial activity against against Escherichia coli 24 assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | 2021 | Bioorganic & medicinal chemistry, 05-15, Volume: 38 | Dipyridyl-substituted thiosemicarbazone as a potent broad-spectrum inhibitor of metallo-β-lactamases. |
| AID203424 | In vitro inhibitory activity against Staphylococci EryRc (23);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID556568 | Antimicrobial activity against katE gene-deficient Escherichia coli K-12 3202 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID564886 | Antibacterial activity against wild-type Escherichia coli AG100 harboring IS186 insertion in lon3 gene, Tn5 insertion in ycgE gene, plasmid pET21b and pACT7SP at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID285196 | Antimicrobial activity against Escherichia coli M074 mutant with AG100 lon2::IS186 acrR::IS genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID555457 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 56 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID509708 | Antibacterial activity against Staphylococcus aureus at 50 ug/ml after 24 hrs by agar cup diffusion method | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of some 3-substituted amino-4,5-tetramethylene thieno[2,3-d][ 1,2,3]-triazin-4(3H)-ones as potential antimicrobial agents. |
| AID529899 | Antimicrobial activity against Leptospira weilii isolate 8 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID520776 | Antibacterial activity against beta-lactamase KPC-2 producing Serratia marcescens isolate S1 to S21 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. |
| AID324999 | Antibacterial activity against Haemophilus paraphrohaemolyticus ATCC 29237 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID365669 | Antibacterial activity against Streptococcus pneumoniae ATCC 49619 after 24 hrs by twofold serial dilution method | 2008 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 18, Issue:16 | Substituted 3-((Z)-2-(4-nitrophenyl)-2-(1H-tetrazol-5-yl) vinyl)-4H-chromen-4-ones as novel anti-MRSA agents: synthesis, SAR, and in-vitro assessment. |
| AID489646 | Antibacterial activity against Citrobacter freundii ATCC 27853 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID509710 | Antibacterial activity against Escherichia coli at 50 ug/ml after 24 hrs by agar cup diffusion method | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of some 3-substituted amino-4,5-tetramethylene thieno[2,3-d][ 1,2,3]-triazin-4(3H)-ones as potential antimicrobial agents. |
| AID648410 | Antibacterial activity against recultured Klebsiella pneumoniae after 16 to 18 hrs by serial dilution method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Facile synthesis, characterization and pharmacological activities of 3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 5,6-dihydro-3,6-disubstituted-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles. |
| AID558322 | Antibacterial activity against bla gene-positive and nitrocefin reaction-negative beta-lactamase harboring Campylobacter jejuni NCTC 11168 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID255533 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 64.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID1827145 | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 assessed as inhibition of bacterial growth after 18 hrs in presence of oxacillin by CLSI protocol based broth microdilution assay | 2022 | ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3 | Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA. |
| AID1419476 | Antimicrobial activity against Bacillus cereus by two fold serial dilution method | 2017 | European journal of medicinal chemistry, May-05, Volume: 131 | Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents. |
| AID1185698 | Antimicrobial activity against Escherichia coli ATCC 25922 after 24 hrs by agar dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | New thiophene-1,2,4-triazole-5(3)-ones: highly bioactive thiosemicarbazides, structures of Schiff bases and triazole-thiols. |
| AID1423475 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC BAA-44 after 6 to 8 hrs by bacterial proliferation assay | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID1868108 | Antibacterial activity against Escherichia coli ATCC 8739 assessed as inhibition of visible bacterial growth incubated for 18 hrs by CLSI protocol based assay | 2022 | Journal of natural products, 05-27, Volume: 85, Issue:5 | Enceleamycins A-C, Furo-Naphthoquinones from |
| AID363845 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 after 18 hrs by macro broth dilution assay | 2008 | European journal of medicinal chemistry, Jul, Volume: 43, Issue:7 | Synthesis, potent anti-staphylococcal activity and QSARs of some novel 2-anilinobenzazoles. |
| AID1596681 | Bactericidal activity against Salmonella typhimurium ATCC 13311 incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID555216 | Antibacterial activity against Escherichia coli DH5alpha carrying ampC gene of Acinetobacter genomosp. 3 isolate 20 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1546088 | Antimicrobial activity against Pseudomonas aeruginosa | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID442418 | Antimicrobial activity against Staphylococcus aureus at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID546974 | Antibacterial activity against Aeromonas sobria assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID318718 | Antimicrobial activity against Escherichia coli SPA27 upto 100 ug/ml by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID1774192 | Antibacterial activity against Escherichia coli delta cirA delta fiu assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID1299580 | Antibacterial activity against Pseudomonas aeruginosa PAO1 ATCC 47085 incubated overnight by microbroth dilution method | 2016 | Journal of medicinal chemistry, Apr-14, Volume: 59, Issue:7 | Antibacterial Diamines Targeting Bacterial Membranes. |
| AID717350 | Antimicrobial activity against Bacillus subtilis ATCC 6633 after 24 hrs | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12 | Brominated aromatic furanones and related esters from the ascidian Synoicum sp. |
| AID1908129 | Antibacterial activity against multi-drug resistant Acinetobacter baumannii ATCC 19606 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID681350 | TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT1-expressing LLC-PK1 cells | 1997 | The American journal of physiology, 11, Volume: 273, Issue:5 | Recognition of beta-lactam antibiotics by rat peptide transporters, PEPT1 and PEPT2, in LLC-PK1 cells. |
| AID644242 | Antibacterial activity against pencillin-resistant Streptococcus pneumoniae after 16 to 20 hrs by two fold agar dilution method | 2012 | European journal of medicinal chemistry, Mar, Volume: 49 | Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2. |
| AID1471041 | Growth inhibition of Staphylococcus aureus NCIM 2602 at 1 ug/ml measured after 12 hrs relative to control | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID1648086 | Antibacterial activity against Proteus hauseri NBRC 3851 assessed as reduction in microbial growth after 24 hrs by two-fold serial dilution method | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Absolute Configuration and Antibiotic Activity of Piceamycin. |
| AID554988 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 56 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID556564 | Antimicrobial activity against sodA, sodB gene-deficient Escherichia coli K-12 3156 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID1139541 | Antibacterial activity against Escherichia coli DH5alpha expressing beta-lactamase TEM-24 by CLSI broth microdilution method | 2014 | Journal of medicinal chemistry, May-08, Volume: 57, Issue:9 | Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. |
| AID540210 | Clearance in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID562388 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecalis clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID568828 | Antimicrobial activity against Staphylococcus aureus ATCC 29737 at 25 ug/ml by agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis of 4H-chromene, coumarin, 12H-chromeno[2,3-d]pyrimidine derivatives and some of their antimicrobial and cytotoxicity activities. |
| AID448152 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 at 10 ug after 18 hrs by well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis of some new 1,2,4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities. |
| AID555475 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 195 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID587243 | Antimicrobial activity against Klebsiella pneumoniae DSM 681 at 1 ug/ul after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID1411626 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hrs by microdilution method | |||
| AID562941 | Effect on fbp69 gene expression in Clostridium difficile 6269 at 0.5 times MIC by real-time PCR analysis | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID1378894 | Antibacterial activity against Bacillus megaterium ATCC 14591 assessed as diameter of inhibition zone at 100 uM after 24 hrs by cup diffusion method | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Synthesis, antimicrobial, DNA cleavage and antioxidant activities of tricyclic sultams derived from saccharin. |
| AID362538 | Antibacterial activity against Bacillus subtilis by agar well diffusion method | 2008 | Journal of natural products, Aug, Volume: 71, Issue:8 | Bioactive 5alpha-pregnane-type steroidal alkaloids from Sarcococca hookeriana. |
| AID577196 | Increase in shiga toxin production in Escherichia coli O157:H7 PT-40 in logarithmic phase encoding Stx-2 gene at 0.5 X MIC by luciferase assay relative to untreated control | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID1204970 | Antimicrobial activity against Escherichia coli ATCC 35270 after 24 hrs by twofold dilution method | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Additional sesterterpenes and a nortriterpene saponin from the sponge Clathria gombawuiensis. |
| AID1176776 | Antimicrobial activity against methicillin-sensitive and vancomycin-intermediate Staphylococcus aureus ATCC 25923 after 24 hrs by broth microdilution method | 2015 | Journal of natural products, Jan-23, Volume: 78, Issue:1 | Structure and antimicrobial activity of phloroglucinol derivatives from Achyrocline satureioides. |
| AID525582 | Ratio of Kcat to Km for Beta-lactamase OXA-1 expressed in Escherichia coli BL21 (DE3) | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Penicillin sulfone inhibitors of class D beta-lactamases. |
| AID1055630 | Antibacterial activity against Escherichia coli MTCC 443 assessed as growth inhibition after 24 hrs by broth microdilution method | 2013 | European journal of medicinal chemistry, , Volume: 70 | Synthesis and antimicrobial activity of some novel hydrazide, benzochromenone, dihydropyridine, pyrrole, thiazole and thiophene derivatives. |
| AID278538 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium breve R0070 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID544521 | Antibacterial activity against Escherichia coli K-12 W3110 infected in mouse assessed as increase of mouse survival at 100 to 300 ug, ip administered 15 mins and 12 hrs postinfection measured after 48 hrs post dose | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Variations in amino acid composition of antisense peptide-phosphorodiamidate morpholino oligomer affect potency against Escherichia coli in vitro and in vivo. |
| AID530499 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype IA isolate 3047-05 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID530255 | Antimicrobial activity against dksA deficient Escherichia coli K-12 BW-25113 assessed as decrease in persistence at 100 ug/ml after 3 hrs by time kill analysis | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. |
| AID1546117 | Antifungal activity against Candida krusei | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID64738 | Influence of porins and TonB on antibacterial activity in Escherichia coli (AB2847) using agar diffusion assay | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID373986 | Antimicrobial activity against azide-resistant aac(6')-Ib-cr expressing Escherichia coli J53 qnrA1 bearing pHS3 transconjugant from Citrobacter freundii 64 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID463411 | Antimicrobial activity against Staphylococcus aureus after 24 hrs by liquid dilution method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines. |
| AID1286496 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 29213 after 20 to 24 hrs in presence of 50% heat inactivated bovine serum | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID567766 | Antimicrobial activity against Escherichia coli ATCC 25922 after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID530257 | Antimicrobial activity against dnaJ deficient Escherichia coli K-12 BW-25113 assessed as decrease in persistence at 100 ug/ml after 3 hrs by time kill analysis | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. |
| AID1433835 | Antibacterial activity against Streptococcus pneumoniae MTCC 1936 after 24 to 48 hrs by broth microdilution method | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs. |
| AID547781 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237I mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID557998 | Antimicrobial activity in Clostridium butyricum by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID289620 | Antibacterial activity against Escherichia coli after 24 hrs by micro-broth dilution technique | 2007 | European journal of medicinal chemistry, Apr, Volume: 42, Issue:4 | Synthesis, in vitro antibacterial and antifungal evaluations of 2-amino-4-(1-naphthyl)-6-arylpyrimidines. |
| AID1266797 | Antibacterial activity against Kocuria rhizophila NBRC 12708 after 24 hrs at 37 degC by broth dilution method | 2015 | Journal of natural products, Nov-25, Volume: 78, Issue:11 | Meroterpenoids from a Tropical Dysidea sp. Sponge. |
| AID1527469 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 1688 assessed as reduction in microbial growth after 24 to 48 hrs by broth dilution method | 2020 | European journal of medicinal chemistry, Jan-01, Volume: 185 | Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents. |
| AID495325 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with Asp350Asn, Ser357Asp, Met377Ile, Ser385Thr, Arg517His substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID1265696 | Toxicity in Pseudoalteromonas lipolytica TC8 assessed as effect on viability at 100 uM after 6 hrs by resazurin-staining assay relative to control | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Click-based synthesis of bromotyrosine alkaloid analogs as potential anti-biofilm leads for SAR studies. |
| AID562472 | Antimicrobial activity against Klebsiella pneumoniae isolate 2641/08 obtained from urine of patient with ischemic cardiomyopathy and several comorbidities by Etest | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Emergence of Klebsiella pneumoniae ST258 with KPC-2 in Poland. |
| AID654569 | Antibacterial activity against Pseudomonas aeruginosa after 18 hrs by broth microdilution method | 2012 | Journal of natural products, Feb-24, Volume: 75, Issue:2 | Asperolides A-C, tetranorlabdane diterpenoids from the marine alga-derived endophytic fungus Aspergillus wentii EN-48. |
| AID477411 | Antibacterial activity against MBX-1090-resistant Staphylococcus aureus isolate d20A1 after 16 to 20 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR. |
| AID723720 | Antibacterial activity against Salmonella typhi after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID1202847 | Antimicrobial activity against Escherichia coli at 10 ug/disc by disc diffusion assay | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Puupehenol, a potent antioxidant antimicrobial meroterpenoid from a Hawaiian deep-water Dactylospongia sp. sponge. |
| AID1141101 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 after 24 to 48 hrs by two-fold broth microdilution method | 2014 | Bioorganic & medicinal chemistry, May-15, Volume: 22, Issue:10 | Exploring 5-nitrofuran derivatives against nosocomial pathogens: synthesis, antimicrobial activity and chemometric analysis. |
| AID530523 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype III isolate 8607 expressing multiple copies of wild-type pbp2x by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID1769959 | Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC48966 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID556758 | Bactericidal activity against katE gene-deficient Escherichia coli K-12 3202 after 18 hrs | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID567769 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as >99.9 % reduction in CFU after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID1769811 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 assessed as inhibition of bacterial growth incubated for 16 to 18 hrs by broth micro dilution technique | |||
| AID545463 | Antimicrobial activity against Pasteurella sp. assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID521433 | Antibacterial activity against Stenotrophomonas maltophilia isolate KJ deficient in L2 beta lactamase gene at 50 ug/ml | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Induction of L1 and L2 beta-lactamases of Stenotrophomonas maltophilia. |
| AID574175 | Antibacterial activity against Escherichia coli MG1655 harboring grown as biofilms plasmid pBR322 carrying blaTEM-1 and tetA(C) genes assessed as decrease in bacterial biofilms formation at 5 ug/ml by GFP assay | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID512148 | Antibacterial activity against Staphylococcus aureus MTCC 1144 after 12 to 16 hrs by turbidity assay | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antiviral and antibacterial agents. |
| AID557700 | Antimicrobial activity in Prevotella loescheii by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID545466 | Antimicrobial activity against Pseudomonas fluorescens assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID776463 | Antimicrobial activity against Escherichia coli ATCC 25922 at 10 ug | 2013 | European journal of medicinal chemistry, Nov, Volume: 69 | Design, synthesis and biological activities of some 7-aminocephalosporanic acid derivatives. |
| AID549332 | Antimicrobial activity against Escherichia coli isolate 86 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID1594842 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 by microdilution method | 2019 | Journal of natural products, 06-28, Volume: 82, Issue:6 | Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. |
| AID289313 | Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate after 24 hrs | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18 | Synthesis and antimicrobial activity of some new thiazolyl thiazolidine-2,4-dione derivatives. |
| AID425866 | Antimicrobial activity against Carnobacterium divergens BM4489 expressing beta-lactamase CAD1 at 3 McFarland inoculum size by E-test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens. |
| AID320390 | Antimicrobial activity against Staphylococcus aureus NCIM2122 by broth microdilution method | 2008 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 18, Issue:6 | Synthesis and antimicrobial activity of beta-lactam-bile acid conjugates linked via triazole. |
| AID584291 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus fleurettii SFMP01(CCUG 43834T) by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID537661 | Antibacterial activity against Escherichia coli ATCC 25922 after 18 hrs by agar-well diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Cyclization of some carbothioamide derivatives containing antipyrine and triazole moieties and investigation of their antimicrobial activities. |
| AID555213 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 195 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1159093 | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID1193891 | Antimicrobial activity against Escherichia coli MTCC 4351 assessed as zone of inhibition at 5 mg/ml after 24 hrs by agar well diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Rapid 'one-pot' synthesis of a novel benzimidazole-5-carboxylate and its hydrazone derivatives as potential anti-inflammatory and antimicrobial agents. |
| AID227700 | Anticonvulsant activity | 2003 | Bioorganic & medicinal chemistry letters, Aug-18, Volume: 13, Issue:16 | Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity. |
| AID1225291 | Antibacterial activity against Proteus hauseri NBRC 3851 incubated for 12 hrs at 37 degC | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Pentacyclic antibiotics from a tidal mud flat-derived actinomycete. |
| AID519639 | Antimicrobial activity against ceftazidime-resistant Escherichia coli Irk2322 harboring beta-lactamase CTX-M-42 Pro167Thr mutant gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID529199 | Antibacterial activity against AmpC-producing Escherichia coli assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Comparison of antimicrobial resistance profiles among extended-spectrum-beta-lactamase-producing and acquired AmpC beta-lactamase-producing Escherichia coli isolates from Canadian intensive care units. |
| AID1774189 | Antibacterial activity against Escherichia coli delta fiu assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID1879068 | Antibacterial activity against NDM-1 positive Escherichia coli ZC-YN3 isolates assessed as inhibition of bacterial growth incubated for 18 to 24 hrs by CLSI based broth microdilution method | 2022 | European journal of medicinal chemistry, Mar-05, Volume: 231 | Metallo-β-lactamases inhibitor fisetin attenuates meropenem resistance in NDM-1-producing Escherichia coli. |
| AID770905 | Antifungal activity against Candida albicans IFO 0583 assessed as growth inhibition at 100 ug/disc after 48 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID251618 | inhibition of Bacillus cereus was measured by zone diameter | 2004 | Bioorganic & medicinal chemistry letters, Dec-06, Volume: 14, Issue:23 | Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: a structure-activity evaluation study. |
| AID533376 | Antimicrobial activity against Bacteroides eggerthii assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID369576 | Antibacterial activity against multidrug-resistant Acinetobacter baumannii 06-74 isolate by CLSI microdilution test | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Colistin methanesulfonate against multidrug-resistant Acinetobacter baumannii in an in vitro pharmacodynamic model. |
| AID278560 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium bifidum BB12 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1457517 | Antibacterial activity against Bacillus subtilis assessed as inhibition of plasma membrane lipids synthesis at 2 mg/L after 50 mins by [3H]-sodium acetate incorporation assay | 2017 | Journal of medicinal chemistry, 07-27, Volume: 60, Issue:14 | Lipophosphonoxins II: Design, Synthesis, and Properties of Novel Broad Spectrum Antibacterial Agents. |
| AID735982 | Antimicrobial activity against Escherichia coli at 1 mg/mL after 24 hrs by agar disc diffusion method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Synthesis and antimicrobial activity of some new benzo and naphthonitrile derivatives. |
| AID425582 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by Etest antibiotic concentration gradient method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID524003 | Antimicrobial activity against Acinetobacter baumannii ATCC 15151 harboring ISAba1-blaOXA-66 gene by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan. |
| AID64065 | In vitro testing for minimum inhibitory concentration against Escherichia coli ATCC 11303. | 1987 | Journal of medicinal chemistry, Dec, Volume: 30, Issue:12 | Design and synthesis of peptide derivatives of a 3-deoxy-D-manno-2-octulosonic acid (KDO) analogue as novel antibacterial agents acting upon lipopolysaccharide biosynthesis. |
| AID555448 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 243 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID330986 | Antimicrobial activity against Enterococcus faecium 49624 | 2007 | Nature, May-03, Volume: 447, Issue:7140 | PTC124 targets genetic disorders caused by nonsense mutations. |
| AID360057 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as lactoyl penta-aspartate-peptide level | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID245338 | Minimum inhibitory concentration required for antibacterial activity against Bacillus subtilis ATCC 6633; gram positive | 2004 | Bioorganic & medicinal chemistry letters, Aug-16, Volume: 14, Issue:16 | Synthesis and QSAR studies of pyrimido[4,5-d]pyrimidine-2,5-dione derivatives as potential antimicrobial agents. |
| AID567280 | Activity of Acinetobacter baumannii ADC-11 beta-lactamase | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Extended-spectrum cephalosporinase in Acinetobacter baumannii. |
| AID1408104 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 24 hrs by two-fold serial dilution method | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157 | Design, synthesis, antimicrobial, antiquorum-sensing and antitumor evaluation of new series of pyrazolopyridine derivatives. |
| AID585867 | Antimicrobial activity against Pseudomonas aeruginosa isolate 14 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID208622 | In vitro antibacterial activity against clinical isolates Ampicillin-insensitive Streptococcus pneumoniae was determined | 1995 | Journal of medicinal chemistry, Jun-09, Volume: 38, Issue:12 | Synthesis and biological evaluation of a series of new parenteral optically active 3-[[(N-alkylpyridinium-4'-yl)thio]methyl]-2-oxaisocephems. |
| AID585874 | Antimicrobial activity against Pseudomonas aeruginosa isolate 17 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID436285 | Antibacterial activity against Micrococcus luteus IFC 12708 after 24 hrs by twofold dilution method | 2008 | Journal of natural products, Nov, Volume: 71, Issue:11 | Scalarane sesterterpenes from the sponge Smenospongia sp. |
| AID508592 | Antibacterial activity against ciprofloxacin-resistant Salmonella enteritidis 104 harboring gyrA D87Y/S83F mutant, soxR R20H mutant and soxS E52K mutant gene after 200 passages by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Fitness costs and stability of a high-level ciprofloxacin resistance phenotype in Salmonella enterica serotype enteritidis: reduced infectivity associated with decreased expression of Salmonella pathogenicity island 1 genes. |
| AID520423 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus saprophyticus isolate TSU18 isolated from genitourinary tracts of acute cystitis patient after 24 hrs at 35 degC by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Methicillin-resistant Staphylococcus saprophyticus isolates carrying staphylococcal cassette chromosome mec have emerged in urogenital tract infections. |
| AID1491295 | Antibacterial activity against Escherichia coli ATCC 25922 after 16 to 20 hrs | 2017 | European journal of medicinal chemistry, Sep-08, Volume: 137 | QSAR-driven design, synthesis and discovery of potent chalcone derivatives with antitubercular activity. |
| AID555218 | Antibacterial activity against Escherichia coli DH5alpha carrying ampC gene of Acinetobacter genomosp. 3 isolate 65 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID575169 | Inhibition of acrAB AcrAB-TolC-mediated Nile Red efflux in Escherichia coli K-12 3-AG100 overexpressing acrAB AcrAB-TolC assessed as time needed for 50% efflux after energization with 50 mM glucose at 1000 uM by spectrofluorometric assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. |
| AID318717 | Antimicrobial activity against Bacillus thuringiensis var. kurstaki BGSC 4D1 by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID564815 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID582966 | Antimicrobial activity against beta-lactamase A-deficient Yersinia enterocolitica GY5717 after 20 hrs by Etest | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Contribution of BlaA and BlaB beta-lactamases to antibiotic susceptibility of Yersinia enterocolitica biovar 1B. |
| AID324215 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 assessed as cell count in stationary phase at 100 ug/ml after 1 day | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID530521 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype III isolate 8607-03 expressing pbp2x Q557E mutant and harboring empty vector by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID278534 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium animalis ATCC 27536 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID529586 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-12 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID1180296 | Bactericidal activity against Escherichia coli NCIM-2256 after 72 hrs by two fold serial macrodilution technique | 2014 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15 | One pot three components microwave assisted and conventional synthesis of new 3-(4-chloro-2-hydroxyphenyl)-2-(substituted) thiazolidin-4-one as antimicrobial agents. |
| AID544465 | Antibacterial activity against Escherichia coli K-12 W3110 infected in mouse assessed as reduction of bacterial level in blood at 100 to 300 ug, ip administered 15 mins and 12 hrs postinfection relative to control | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Variations in amino acid composition of antisense peptide-phosphorodiamidate morpholino oligomer affect potency against Escherichia coli in vitro and in vivo. |
| AID405312 | Antibacterial activity against beta-lactamase producing amoxicillin-clavulanic acid-resistant Haemophilus influenzae isolate assessed as percent resistant isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID510159 | Antimicrobial activity against extended spectrum beta lactamase expressing Proteus mirabilis by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID648409 | Antibacterial activity against Pseudomonas aeruginosa ATTC 27853 at MIC after 3 to 4 days by disc diffusion method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Facile synthesis, characterization and pharmacological activities of 3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 5,6-dihydro-3,6-disubstituted-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles. |
| AID369626 | Antimicrobial activity against beta-lactamase negative ampicillin-susceptible Haemophilus influenzae by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Can the Etest correctly determine the MICs of beta-lactam and cephalosporin antibiotics for beta-lactamase-negative ampicillin-resistant Haemophilus influenzae? |
| AID442415 | Antimicrobial activity against Listeria monocytogenes at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID723719 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID1379752 | Antimicrobial activity against Staphylococcus aureus incubated for 24 hrs by serial dilution method | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of cyclopenta(hepta)[b]thiophene and fused cyclohepta[b]thiophene analogs. |
| AID495322 | Antimicrobial activity against Beta-lactamase-positive, ampicillin-resistant Haemophilus influenzae by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID489650 | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID565231 | Antimicrobial activity against Mycobacterium chelonae 9917 harboring pZS01 carrying mspA gene by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID614154 | Antimicrobial activity against Salmonella Typhimurium ATCC 14028 | 2011 | Journal of natural products, Aug-26, Volume: 74, Issue:8 | Sesterterpenes from the tropical sponge Coscinoderma sp. |
| AID64882 | Influence of porins and TonB on antibacterial activity in Escherichia coli (KB5) using agar diffusion assay | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID64876 | Influence of siderophore receptor on antibacterial activity in Escherichia coli (H873) using agar diffusion assay | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID546924 | Antibacterial activity against Salmonella enterica serovar Typhimurium by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID334235 | Antimicrobial activity against Microsporum gypseum NCPF 40 after 10 days by microdilution technique | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4 | Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline. |
| AID1854168 | Antimicrobial activity against Escherichia coli ATCC 8739 | 2022 | European journal of medicinal chemistry, Aug-05, Volume: 238 | Cascade synthetic strategies opening access to medicinal-relevant aliphatic 3- and 4-membered N-heterocyclic scaffolds. |
| AID520986 | Antimicrobial activity against Acinetobacter baumannii ATCC 19606 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Novel antimicrobial peptides that exhibit activity against select agents and other drug resistant bacteria. |
| AID1616521 | Antibacterial activity against Bacillus subtilis after 24 hrs by broth microdilution method | 2019 | Journal of natural products, 10-25, Volume: 82, Issue:10 | Highly Oxygenated Triterpenoids and Rare Tetraterpenoids from |
| AID1651556 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as reduction in microbial growth after incubated for 48 hrs by resazurin dye based assay | 2020 | Journal of natural products, 04-24, Volume: 83, Issue:4 | Talauxins: Hybrid Phenalenone Dimers from |
| AID537663 | Antibacterial activity against Yersinia pseudotuberculosis ATCC 911 after 18 hrs by agar-well diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Cyclization of some carbothioamide derivatives containing antipyrine and triazole moieties and investigation of their antimicrobial activities. |
| AID546935 | Antibacterial activity against Salmonella enterica serovar Paratyphi assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1290443 | Antibacterial activity against Vibrio cholerae MTCC 3906 after 24 to 48 hrs by broth microdilution method | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities. |
| AID547778 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237G mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID304973 | Antifungal activity against Cryptococcus neoformans by broth micro-dilution technique | 2007 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1 | New antifungal flavonoid glycoside from Vitex negundo. |
| AID1185313 | Antibacterial activity Pseudomonas aeruginosa ATCC-27853 assessed as growth inhibition after 24 hrs by twofold serial dilution technique | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis and 3D-QSAR studies of new diphenylamine containing 1,2,4-triazoles as potential antitubercular agents. |
| AID1759337 | Antibacterial activity against Bacillus subtilis MTCC 441 assessed as bacterial growth inhibition by microdilution method | 2021 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 41 | Design and synthesis, biological evaluation of bis-(1,2,3- and 1,2,4)-triazole derivatives as potential antimicrobial and antifungal agents. |
| AID1778091 | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as inhibition of bacterial growth incubated for 18 hrs by broth microdilution method | |||
| AID1265196 | Antibacterial activity against methicillin-resistant Staphylococcus aureus NCTC 13616 after 24 hrs by microtiter plate method | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes. |
| AID612540 | Binding affinity to human PepT2 in SKTP cells | 2011 | Bioorganic & medicinal chemistry, Aug-01, Volume: 19, Issue:15 | Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping. |
| AID555453 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 21 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID511058 | Antibacterial activity against Escherichia coli MTCC 443 by broth microdilution method | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Pharmacological evaluation and characterizations of newly synthesized 1,2,4-triazoles. |
| AID736473 | Antibacterial activity against Shigella flexneri RCMB 0100542 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID558795 | Antimicrobial activity against extended spectrum beta-lactamase-expressing Escherichia coli assessed as percent susceptible isolates by CLSI method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007. |
| AID545439 | Antimicrobial activity against extended-Spectrum beta-lactamase-negative Escherichia coli obtained from patient with complicated intra-abdominal infection assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhib | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID548004 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237P mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID1262362 | Antibacterial activity against clinical isolates Staphylococcus aureus after 24 hrs by agar diffusion assay | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | PPL catalyzed four-component PASE synthesis of 5-monosubstituted barbiturates: Structure and pharmacological properties. |
| AID548008 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237Q mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID163410 | Minimum inhibitory concentration of Ampicillin required for growth inhibition of Beta lactamase producing bacteria Proteus vulgaris (IID OX-19) | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8 | Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives. |
| AID360071 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as tetra -aspartate-penta multimer containing D-Ala4 to D-Asp-L-Lys3 cross links at 128 ug/ml by mass spectrometry | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID559698 | Antibacterial activity against quinolone-resistant Escherichia coli TOP10-3963 transformant harboring qnrS1 gene by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | First report of plasmid-mediated quinolone resistance determinant qnrS1 in an Escherichia coli strain of animal origin in Italy. |
| AID559582 | Antimicrobial activity against Chlamydophila psittaci infected in Vero cells | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antibiotic susceptibility of Waddlia chondrophila in Acanthamoeba castellanii amoebae. |
| AID360062 | Inhibition of Enterococcus faecium M512 LDtfm transpeptidase activity assessed as tri-aspartate-penta multimer containing L-Lys3 to D-Asp-L-Lys3 cross links at 8 ug/ml | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID1527491 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus clinical isolate MRSA1 assessed as reduction in microbial growth by two-fold serial dilution method | 2020 | European journal of medicinal chemistry, Jan-01, Volume: 185 | Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents. |
| AID535643 | Antimicrobial activity against Group B streptococcus serotype III N3 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID585678 | Antimicrobial activity against ampG deficient Pseudomonas aeruginosa PAK after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1412926 | Antibacterial activity against Enterobacter cloacae clinical isolate by microdilution method | 2018 | MedChemComm, May-01, Volume: 9, Issue:5 | Design, synthesis and antimicrobial activity of usnic acid derivatives. |
| AID520706 | Antibacterial activity against Acinetobacter baumannii phenotype 1 by disk diffusion method in presence of 4 ug/ml clavulanic acid | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID1399274 | Antimicrobial activity against Escherichia coli isolate SJ 2 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID324236 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoU mutant assessed as cell count in log phase at 100 ug/ml after 1 week | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1695930 | Antibacterial activity against Salmonella typhimurium ATCC 14028 incubated for 24 hrs by broth dilution method | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID405080 | Antimicrobial activity against Citrobacter freundii 33587 isolate by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Biochemical characterization of PER-2 and genetic environment of blaPER-2. |
| AID295113 | Antibacterial activity against Mycobacterium smegmatis CCM 2067 at 10 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID584475 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN05 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID318704 | Antimicrobial activity against Bacillus subtilis ATCC 6633 by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID530229 | Antimicrobial activity against Mycobacterium bovis BCG ML1062 carrying transposon IS1096::Km inserted at -18bp of pks11 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID551097 | Antibacterial activity against Salmonella Typhimurium by liquid dilution method | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1 | 3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents. |
| AID770913 | Antibacterial activity against Micrococcus luteus IFO 3232 after 24 hrs by two fold dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID537664 | Antibacterial activity against Pseudomonas aeruginosa ATCC 43288 after 18 hrs by agar-well diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Cyclization of some carbothioamide derivatives containing antipyrine and triazole moieties and investigation of their antimicrobial activities. |
| AID1185235 | Antimicrobial activity against Streptococcus pneumoniae RCMB 010010 assessed as absence of turbidity after 24 hrs | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis, antimicrobial evaluation and molecular docking studies of some new thiophene, pyrazole and pyridone derivatives bearing sulfisoxazole moiety. |
| AID585871 | Antimicrobial activity against Pseudomonas aeruginosa isolate 16 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID633850 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID644178 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID1648087 | Antibacterial activity against Klebsiella pneumoniae ATCC 10031 assessed as reduction in microbial growth after 24 hrs by two-fold serial dilution method | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Absolute Configuration and Antibiotic Activity of Piceamycin. |
| AID1634723 | Antibacterial activity against methicillin-resistant Staphylococcus aureus by microdilution assay | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | 18β-Glycyrrhetinic Acid Derivatives Possessing a Trihydroxylated A Ring Are Potent Gram-Positive Antibacterial Agents. |
| AID559330 | Antimicrobial activity against Salmonella enterica clinical isolates assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID547798 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237F mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID582915 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61K mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1535454 | Growth inhibition of Pseudoalteromonas lipolytica TC8 at 5 uM measured every hr for 6 hrs by turbidimetric method | 2019 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 29, Issue:4 | Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds? |
| AID662988 | Antibacterial activity against Clostridium tetani MTCC 449 by macrobroth dilution assay | 2012 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 22, Issue:12 | An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidines. |
| AID1272236 | Antibacterial activity against Pseudomonas aeruginosa by broth micro-dilution method | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3 | Efficiently functionalized oxacalix[4]arenes: Synthesis, characterization and exploration of their biological profile as novel HDAC inhibitors. |
| AID520871 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus saprophyticus isolate TSU57 isolated from genitourinary tracts of acute cystitis patient after 24 hrs at 35 degC by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Methicillin-resistant Staphylococcus saprophyticus isolates carrying staphylococcal cassette chromosome mec have emerged in urogenital tract infections. |
| AID587984 | Antibacterial activity against Escherichia coli AS226 carrying pBSDF160T mutant after 18 hrs by broth microdilution method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID565229 | Antimicrobial activity against Mycobacterium chelonae ATCC 35752 harboring pZS01 carrying mspA gene by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID372563 | Antibacterial activity against genetically beta-lactamase-positive amoxicillin-clavulanate-resistant Haemophilus influenzae type b with an amino acid substitution in highly mutated locus Ser-385 of ftsI gene assessed as resistance rate by broth microdilut | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID345809 | Antimicrobial activity against Escherichia coli ATCC 11229 | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24 | Synthesis and antimicrobial activity of 2-alkenylchroman-4-ones, 2-alkenylthiochroman-4-ones and 2-alkenylquinol-4-ones. |
| AID325486 | Antimicrobial activity against beta-lactamase producing Enterococcus faecalis TX5070 isolate by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Time-kill and synergism studies of ceftobiprole against Enterococcus faecalis, including beta-lactamase-producing and vancomycin-resistant isolates. |
| AID583431 | Antimicrobial activity against methicillin-resistant and tetracycline-sensitive Staphylococcus aureus COLn | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | A mecA-negative strain of methicillin-resistant Staphylococcus aureus with high-level β-lactam resistance contains mutations in three genes. |
| AID775962 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition at 100 ug/mL after 18 to 24 hrs by microdilution assay | 2013 | European journal of medicinal chemistry, Nov, Volume: 69 | Synthesis, antibacterial and antioxidant activities of new 1-alkyl-4-(1-alkyl-4-oxo-1,4-dihydroquinolin-2-yl)pyridinium bromides. |
| AID565058 | Antibacterial activity against wild-type Escherichia coli AG100 harboring Tn5 insertion in ycgE gene at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID495338 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID424867 | Antibacterial activity against bacterial sensory kinase PhoQ deficient Salmonella enterica serovar Typhimurium CS009 by modified twofold broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | The PhoQ-activating potential of antimicrobial peptides contributes to antimicrobial efficacy and is predictive of the induction of bacterial resistance. |
| AID1577949 | Antimicrobial activity against Pseudomonas aeruginosa 61 under iron-deficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID551095 | Antibacterial activity against Escherichia coli by liquid dilution method | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1 | 3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents. |
| AID723722 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID1265198 | Antibacterial activity against Bacillus cereus ATCC 14579 after 24 hrs by microtiter plate method | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes. |
| AID365667 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 032 after 24 hrs by twofold serial dilution method | 2008 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 18, Issue:16 | Substituted 3-((Z)-2-(4-nitrophenyl)-2-(1H-tetrazol-5-yl) vinyl)-4H-chromen-4-ones as novel anti-MRSA agents: synthesis, SAR, and in-vitro assessment. |
| AID585630 | Antimicrobial activity against gentamycin resistant Escherichia coli SNO301-1 harboring pEC1C carrying ampC, ampR from Enterobacter cloacae after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID495343 | Antimicrobial activity against Beta-lactamase-positive, ampicillin-cluvulanate-resistant Haemophilus influenzae with Ala502Val, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID1352297 | Anti-fungal activity against Candida albicans at 30 ug/disk | 2018 | European journal of medicinal chemistry, Feb-10, Volume: 145 | Bysspectin A, an unusual octaketide dimer and the precursor derivatives from the endophytic fungus Byssochlamys spectabilis IMM0002 and their biological activities. |
| AID294833 | Antibacterial activity against Escherichia coli after 24 hrs by microdilution broth method | 2007 | Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8 | Identification of antitumour activity of novel derivatives of 8-aryl-2,6,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazine-3,4-dione and 8-aryl-4-imino-2,3,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazin-3(6H)-one. |
| AID1434049 | Antibacterial activity against Pseudomonas aeruginosa NCIM 2036 by standard agar method | 2017 | Bioorganic & medicinal chemistry letters, 02-01, Volume: 27, Issue:3 | Antileishmanial evaluation of clubbed bis(indolyl)-pyridine derivatives: One-pot synthesis, in vitro biological evaluations and in silico ADME prediction. |
| AID735218 | Antimicrobial activity against Streptococcus pyogenes MTCC 442 assessed as growth inhibition measured after overnight incubation by broth dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | New 2-benzylsulfanyl-nicotinic acid based 1,3,4-oxadiazoles: their synthesis and biological evaluation. |
| AID509324 | Antibacterial activity against ampicillin-resistant Pseudomonas putida MTCC 1072 after 12 to 16 hrs by turbidity assay | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antiviral and antibacterial agents. |
| AID1079933 | Acute liver toxicity defined via clinical observations and clear clinical-chemistry results: serum ALT or AST activity > 6 N or serum alkaline phosphatases activity > 1.7 N. This category includes cytolytic, choleostatic and mixed liver toxicity. Value is | |||
| AID1355479 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 48 hrs by resazurin dye based assay | 2018 | Journal of natural products, 07-27, Volume: 81, Issue:7 | Banksialactones and Banksiamarins: Isochromanones and Isocoumarins from an Australian Fungus, Aspergillus banksianus. |
| AID362536 | Antibacterial activity against Streptococcus faecalis assessed as zone of inhibition at 0.25 mg/mL by agar well diffusion method | 2008 | Journal of natural products, Aug, Volume: 71, Issue:8 | Bioactive 5alpha-pregnane-type steroidal alkaloids from Sarcococca hookeriana. |
| AID1668054 | Inhibition of DHPS in Staphylococcus epidermidis assessed as antibacterial activity by measuring inhibition zone at 5 mg/mL incubated for 24 hrs by disk diffusion method | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9 | New acrylamide-sulfisoxazole conjugates as dihydropteroate synthase inhibitors. |
| AID285195 | Antimicrobial activity against Escherichia coli M073 mutant with AG100 lon2::IS186 acrR::IS5 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID278232 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-1 GyrA S83F mutant | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID405306 | Antibacterial activity against beta-lactamase nonproducing ampicillin susceptible Haemophilus influenzae isolate assessed as percent resistant isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID64752 | Influence of siderophore receptor on antibacterial activity in Escherichia coli (H1877) using agar diffusion assay | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID1176775 | Antimicrobial activity against methicillin-resistant and vancomycin-intermediate Staphylococcus aureus NRS402 after 24 hrs by broth microdilution method | 2015 | Journal of natural products, Jan-23, Volume: 78, Issue:1 | Structure and antimicrobial activity of phloroglucinol derivatives from Achyrocline satureioides. |
| AID94143 | In vitro antibacterial activity against ATCC 100331 strain of Klebsiella pneumoniae | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID1132045 | Antibacterial activity against Staphylococcus aureus Oxford | 1978 | Journal of medicinal chemistry, Jan, Volume: 21, Issue:1 | Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. |
| AID1870143 | Antibacterial activity against wild type Staphylococcus aureus 4862/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID585397 | Activity at Stenotrophomonas maltophilia 1SML metallo-beta-lactamase L1 | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides. |
| AID543793 | Antimicrobial activity against Haemophilus influenzae VT450-2006 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID477029 | Antimicrobial activity against Klebsiella pneumoniae at 2 mg/ml after 24 hrs by agar diffusion assay | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activities of some new thiazole and pyrazole derivatives based on 4,5,6,7-tetrahydrobenzothiophene moiety. |
| AID405823 | Antimicrobial activity against Acinetobacter baumannii 9043 isolate harboring bla IMP-1 carrying integron In86 containing aminoglycoside resistance gene aac(6')-3 | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital. |
| AID333999 | Antibacterial activity against Escherichia coli at 200 ug/100 uL after 24 hrs by tube broth dilution method | 1997 | Journal of natural products, Oct, Volume: 60, Issue:10 | New steroidal alkaloids from Buxus longifolia. |
| AID467967 | Antimicrobial activity against Staphylococcus aureus ATCC 12600 after 18 to 24 hrs by liquid broth method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. |
| AID585672 | Antimicrobial activity against ampD, ampDh2, ampDh3 deficient Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID555465 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 69 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID671466 | Antibacterial activity against Staphylococcus epidermidis ATCC 35984 after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Aug-01, Volume: 20, Issue:15 | Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. |
| AID1385488 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolate 1862 by two-fold serial dilution method | 2018 | Journal of natural products, 08-24, Volume: 81, Issue:8 | Abyssomicin Monomers and Dimers from the Marine-Derived Streptomyces koyangensis SCSIO 5802. |
| AID558326 | Antibacterial activity against bla gene-negative and nitrocefin reaction-negative beta-lactamase harboring Campylobacter jejuni isolate P1962 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID1075971 | Antifungal activity against Aspergillus flavus after 72 hrs by broth micro-dilution method | 2014 | European journal of medicinal chemistry, Mar-21, Volume: 75 | Toward new classes of potent antibiotics: synthesis and antimicrobial activity of novel metallosaldach-imidazolium salts. |
| AID278525 | Antimicrobial activity against Bifidobacterium breve ATCC 15700 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID551084 | Antibacterial activity against Staphylococcus aureus at 1000 ug/mL after 72 hrs by agar diffusion assay | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1 | 3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents. |
| AID585832 | Antimicrobial activity against ampG deficient Pseudomonas aeruginosa PAK harboring pUCP24 conferring resistance to gentamycin after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID540966 | Activity of Salmonella enterica serotype Newport AM17274 cephalosporinase CMY-31 by spectrophotometry | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids. |
| AID671475 | Antibacterial activity against Staphylococcus hominis ATCC 27844 after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Aug-01, Volume: 20, Issue:15 | Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. |
| AID1577959 | Antimicrobial activity against Klebsiella pneumoniae X68 under iron-sufficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID333989 | Antibacterial activity against Salmonella typhi at 100 ug/100 uL after 24 hrs by tube broth dilution method | 1997 | Journal of natural products, Oct, Volume: 60, Issue:10 | New steroidal alkaloids from Buxus longifolia. |
| AID324291 | Antibacterial activity against Escherichia coli K12 containing deletion deltahipA mutant assessed as cell count in stationary phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1577951 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 under iron-deficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID565616 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.10 ug/ml (Rvb =798.3 +/- 37.09 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID1653048 | Antibacterial activity against Streptococcus pyogenes | 2019 | European journal of medicinal chemistry, Feb-15, Volume: 164 | Isatin derivatives and their anti-bacterial activities. |
| AID546621 | Antimicrobial activity against Escherichia coli harboring plasmid pPCRScript by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). |
| AID582920 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61I mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1132066 | Antiviral activity against Coxsackievirus B1 infected in human HeLa cells at 1 mg/ml by agar diffusion assay | 1978 | Journal of medicinal chemistry, Jan, Volume: 21, Issue:1 | Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. |
| AID1287102 | Antimicrobial activity against Staphylococcus aureus ATCC 2592 assessed as inhibition of bacterial growth after 16 hrs by broth dilution method | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis. |
| AID1908130 | Antibacterial activity against penicillin-susceptible Pseudomonas aeruginosa ATCC 27853 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID582913 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61N mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID382720 | Antimicrobial activity against Candida albicans ATCC 10231 at 572.4 uM by disc-diffusion method | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives. |
| AID495345 | Antimicrobial activity against Beta-lactamase-positive, ampicillin-cluvulanate-resistant Haemophilus influenzae with Ala368Thr, Ala502Thr, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID776460 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 at 10 ug | 2013 | European journal of medicinal chemistry, Nov, Volume: 69 | Design, synthesis and biological activities of some 7-aminocephalosporanic acid derivatives. |
| AID1499655 | Antimicrobial activity against Staphylococcus aureus RCMB 010028 assessed as diameter of zone inhibition at 100 ug/ml after 24 hrs by agar well diffusion assay | 2017 | European journal of medicinal chemistry, Sep-29, Volume: 138 | Design, synthesis and 2D QSAR study of novel pyridine and quinolone hydrazone derivatives as potential antimicrobial and antitubercular agents. |
| AID1055943 | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 16 hrs | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID1347485 | Antibacterial activity against Klebsiella pneumoniae assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID1439797 | Antibacterial activity against Staphylococcus aureus MTCC 96 incubated for 24 hrs under dark condition by microwell dilution method | 2017 | Bioorganic & medicinal chemistry letters, 04-01, Volume: 27, Issue:7 | Biologically active perspective synthesis of heteroannulated 8-nitroquinolines with green chemistry approach. |
| AID1286495 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 49775 after 20 to 24 hrs in presence of 50% heat inactivated bovine serum | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID601601 | Antibacterial activity against Brevundimonas sp. isolate Fs30 at 10 ug/disk after 24 hrs by disc diffusion assay | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Synthesis of 2-aziridinyl phosphonates by modified Gabriel-Cromwell reaction and their antibacterial activities. |
| AID519111 | Antibacterial activity against Proteus mirabilis NP14 after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID558809 | Antimicrobial activity against extended spectrum beta-lactamase-deficient Klebsiella pneumoniae assessed as percent susceptible isolates by CLSI method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007. |
| AID1132048 | Antibacterial activity against Streptococcus faecalis I | 1978 | Journal of medicinal chemistry, Jan, Volume: 21, Issue:1 | Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. |
| AID535642 | Antimicrobial activity against Group B streptococcus serotype VI N4 harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID1730950 | Antibacterial activity against Streptococcus pyogenes MTCC 442 assessed as bacterial growth inhibition | 2021 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 36 | Structure based design, synthesis, and biological evaluation of imidazole derivatives targeting dihydropteroate synthase enzyme. |
| AID569255 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives. |
| AID530208 | Antimicrobial activity against Mycobacterium bovis BCG ML1007 carrying transposon IS1096::Km inserted at +988bp of ppe53 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1399490 | Bactericidal activity against Staphylococcus aureus ATCC 6538 by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID554985 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 20 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1634720 | Antibacterial activity against Bacillus subtilis ATCC 6051 by microdilution assay | 2016 | Journal of natural products, Apr-22, Volume: 79, Issue:4 | 18β-Glycyrrhetinic Acid Derivatives Possessing a Trihydroxylated A Ring Are Potent Gram-Positive Antibacterial Agents. |
| AID530509 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype III isolate 3789-04 expressing pbp2x Q557E mutant and multilocus sequence type ST19 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID1774195 | Antibacterial activity against Escherichia coli delta exbB assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID736478 | Antibacterial activity against Streptococcus pyogenes RCMB 010015 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID278540 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium longum ATCC 15707 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID300436 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 24 hrs by broth microdilution test | 2007 | Bioorganic & medicinal chemistry, Sep-01, Volume: 15, Issue:17 | 1-Acylthiosemicarbazides, 1,2,4-triazole-5(4H)-thiones, 1,3,4-thiadiazoles and hydrazones containing 5-methyl-2-benzoxazolinones: synthesis, analgesic-anti-inflammatory and antimicrobial activities. |
| AID1648083 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as reduction in microbial growth after 24 hrs by two-fold serial dilution method | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Absolute Configuration and Antibiotic Activity of Piceamycin. |
| AID1143596 | Antibacterial activity against Staphylococcus aureus assessed as growth inhibition after 24 hrs by two fold serial dilution method | 2014 | European journal of medicinal chemistry, Jun-23, Volume: 81 | Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-arylethanones: antibacterial, DNA photocleavage, and anticancer activities. |
| AID1293900 | Antibacterial activity against Staphylococcus aureus after 18 hrs by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9 | Novel tetrazoloquinoline-rhodanine conjugates: Highly efficient synthesis and biological evaluation. |
| AID340737 | Ratio of Kcat to Km of Chryseobacterium indologenes metallo-beta-lactamase IND-5 expressed in Escherichia coli BL21(DE3) assessed as substrate hydrolysis | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Identification and characterization of a new metallo-beta-lactamase, IND-5, from a clinical isolate of Chryseobacterium indologenes. |
| AID520705 | Antibacterial activity against Acinetobacter baumannii phenotype 1 by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID655622 | Antibacterial activity against Burkholderia pseudomallei NTCC 10274 at 40 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID584483 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN13 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID1596674 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID1491342 | Antifungal activity against Candida albicans after 48 hrs by two-fold serial dilution method | 2017 | European journal of medicinal chemistry, Sep-08, Volume: 137 | Synthesis, antimicrobial, antiquorum-sensing and antitumor activities of new benzimidazole analogs. |
| AID530224 | Antimicrobial activity against Mycobacterium bovis BCG ML1050 carrying transposon IS1096::Km inserted at +41bp of bcg2827 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID584293 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus fleurettii SFMP03 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID324293 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoB mutant assessed as cell count in stationary phase at 100 ug/ml after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID644165 | Antibacterial activity against Bacillus cereus clinical isolate after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID1870145 | Antibacterial activity against wild type Staphylococcus aureus 4880/C assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID421837 | Antibacterial activity against Bacillus subtilis ATCC 6633 | 2009 | Journal of natural products, Feb-27, Volume: 72, Issue:2 | Glionitrin A, an antibiotic-antitumor metabolite derived from competitive interaction between abandoned mine microbes. |
| AID529592 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-12 assessed as bacterial density at 1024 ug/ml after 18 hrs | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID536090 | Antimicrobial activity against Escherichia coli IFO 3301 after 24 hrs | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID564814 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus epidermidis assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1683199 | Antibacterial activity against Streptococcus pneumoniae assessed as suppression of visible growth incubated for 24 hrs by CLSI-based broth microdilution method | 2021 | Bioorganic & medicinal chemistry, 01-01, Volume: 29 | Discovery of benzhydrol-oxaborole derivatives as Streptococcus pneumoniae leucyl-tRNA synthetase inhibitors. |
| AID285191 | Antimicrobial activity against Escherichia coli M013 mutant with AG100 delta-(lon-hupB-ppiD) dupIS5 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID1233735 | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as microbial growth inhibition at 1 mg/ml incubated overnight at 37 degC | 2015 | Journal of natural products, Jul-24, Volume: 78, Issue:7 | HPLC-NMR and HPLC-MS Profiling and Bioassay-Guided Identification of Secondary Metabolites from the Australian Plant Haemodorum spicatum. |
| AID1596679 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID1183258 | Antimicrobial activity against Escherichia coli MTCC 443 assessed as absence of visible growth after 24 to 48 hrs by broth micro dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis and characterization of fluoro substituted novel pyrazolylpyrazolines scaffold and their pharmacological screening. |
| AID657433 | Antibacterial activity against methicillin-resistant Staphylococcus aureus after 16 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9 | Preparation, antibacterial evaluation and preliminary structure-activity relationship (SAR) study of benzothiazol- and benzoxazol-2-amine derivatives. |
| AID555238 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 21 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID633848 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID546965 | Antibacterial activity against Yersinia pseudotuberculosis assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID1402050 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 25923 after 18 to 20 hrs by spectrophotometry based microdilution method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid. |
| AID573372 | Antibacterial activity against ceftazidime-susceptible Serratia marcescens assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1585653 | Antibacterial activity against methicillin-resistant Staphylococcus epidermidis after overnight incubation by micro broth dilution analysis | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug resistance of bacterial infections. |
| AID1224740 | Antimicrobial activity against Salmonella typhi MTCC 98 by broth microdilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Ultrasound-assisted one-pot four-component synthesis of novel 2-amino-3-cyanopyridine derivatives bearing 5-imidazopyrazole scaffold and their biological broadcast. |
| AID1653049 | Antibacterial activity against Bacillus subtilis | 2019 | European journal of medicinal chemistry, Feb-15, Volume: 164 | Isatin derivatives and their anti-bacterial activities. |
| AID278567 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium thermophilum ATCC 25866 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID548256 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm mutant gene after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID1399254 | Antimicrobial activity against Bacillus cereus ATCC 14579 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID1890484 | Antibacterial activity against Enterococcus faecium assessed as bacterial growth inhibition incubated for 5 hrs by bromocresol purple dye based assay | 2022 | Journal of natural products, 04-22, Volume: 85, Issue:4 | Antimicrobial Prenylated Isoflavones from the Leaves of the Amazonian Medicinal Plant |
| AID1075973 | Antibacterial activity against Bacillus subtilis after 72 hrs by broth micro-dilution method | 2014 | European journal of medicinal chemistry, Mar-21, Volume: 75 | Toward new classes of potent antibiotics: synthesis and antimicrobial activity of novel metallosaldach-imidazolium salts. |
| AID565671 | Antimicrobial activity against beta-lactamase positive (amoxicillin)clavulanate-resistant Haemophilus influenzae assessed as susceptible isolates by broth microdilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID360834 | Antibacterial activity against Bacillus cereus ATCC 11778 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID1730947 | Antibacterial activity against Pseudomonas aeruginosa MTCC 1688 assessed as bacterial growth inhibition | 2021 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 36 | Structure based design, synthesis, and biological evaluation of imidazole derivatives targeting dihydropteroate synthase enzyme. |
| AID324990 | Antibacterial activity against Haemophilus influenzae MSC07169 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID1721976 | Bactericidal activity against Bacillus subtilis | 2020 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 30, Issue:17 | New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. |
| AID531613 | Antimicrobial activity against Escherichia coli JM109 harboring pE1MD plasmid expressing beta-lactamase SHV-56 by agar dilution method in presence of Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae. |
| AID770917 | Antibacterial activity against Bacillus subtilis IFO 3007 assessed as growth inhibition at 100 ug/disc after 24 hrs by agar disc-diffusion method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones. |
| AID532031 | Antimicrobial activity against Escherichia coli TOP10F' by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. |
| AID495330 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with Asp350Asn, Met377Ile, Ala502Val, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID545430 | Antimicrobial activity against Enterobacter cloacae obtained from patient with complicated intra-abdominal infection assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID725079 | Antimicrobial activity against Bacillus subtilis after 12 to 18 hrs by micro-well dilution method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Synthesis and antibacterial and antifungal evaluation of some chalcone based sulfones and bisulfones. |
| AID1314117 | Antibacterial activity against Escherichia coli K-12 in M9 minimal media in presence of methionine by turbidometric method | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16 | Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents. |
| AID765559 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 43288 after 18 to 24 hrs by double microdilution method | 2013 | European journal of medicinal chemistry, Sep, Volume: 67 | Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities. |
| AID535364 | Antimicrobial activity against Haemophilus influenzae clinical isolates assessed as resistant isolates by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Antimicrobial resistance among respiratory pathogens in Spain: latest data and changes over 11 years (1996-1997 to 2006-2007). |
| AID757695 | Antibacterial activity against Staphylococcus aureus ATCC 12600 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis, antitumor and antibacterial activities of some novel tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives. |
| AID529608 | Antibacterial activity against Beta-lactamase negative Haemophilus influenzae with PBP3 mutation | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID557680 | Antimicrobial activity in Prevotella baroniae by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID531317 | Activity of Escherichia coli beta-lactamase VIM-1 by spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family. |
| AID447064 | Antibacterial activity against Klebsiella pneumoniae UC57 at 10 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID670272 | Antibacterial activity against Salmonella typhimurium ATCC 14028 after 24 hrs | 2012 | Bioorganic & medicinal chemistry, Jul-01, Volume: 20, Issue:13 | Beta-carboline alkaloids derived from the ascidian Synoicum sp. |
| AID251628 | inhibition of Pseudomonas aeruginosa was measured by zone diameter | 2004 | Bioorganic & medicinal chemistry letters, Dec-06, Volume: 14, Issue:23 | Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: a structure-activity evaluation study. |
| AID530503 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype IA isolate 9012-04 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID542769 | Antimicrobial activity against Escherichia coli J53 transformed with pHND1 carrying DHA-1 gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID548482 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega after 48 hrs by Etest in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID680671 | TP_TRANSPORTER: inhibition of VACV uptake (VAVC: 20 uM, Ampicillin: 10000 uM) in PEPT1-expressing CHO cells | 1999 | The Journal of pharmacology and experimental therapeutics, Apr, Volume: 289, Issue:1 | Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line. |
| AID670270 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs | 2012 | Bioorganic & medicinal chemistry, Jul-01, Volume: 20, Issue:13 | Beta-carboline alkaloids derived from the ascidian Synoicum sp. |
| AID1105402 | Antibacterial activity against Bacillus thuringiensis MTCC 6941 assessed as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID487478 | Antibacterial activity against Staphylococcus aureus NCIM 2079; ATCC 6538P after 24 hrs by microtitration method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Design, synthesis, characterization, and antibacterial activity of {5-chloro-2-[(3-substitutedphenyl-1,2,4-oxadiazol-5-yl)-methoxy]-phenyl}-(phenyl)-methanones. |
| AID1399503 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hrs by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID1647641 | Antibacterial activity against Proteus hauseri NBRC 3851 assessed as reduction in microbial growth | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Isocadiolides A-H: Polybrominated Aromatics from a |
| AID523889 | Antimicrobial activity against Acinetobacter baumannii 6AB15 harboring ISAba1-blaOXA-23 and blaOXA-66 gene by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan. |
| AID765560 | Antimicrobial activity against Escherichia coli ATCC 25922 after 18 to 24 hrs by double microdilution method | 2013 | European journal of medicinal chemistry, Sep, Volume: 67 | Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities. |
| AID369632 | Antimicrobial activity against beta-lactamase positive amoxicillin/clavulanate-resistant Haemophilus influenzae by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Can the Etest correctly determine the MICs of beta-lactam and cephalosporin antibiotics for beta-lactamase-negative ampicillin-resistant Haemophilus influenzae? |
| AID1194192 | Antimicrobial activity against Aspergillus niger after 48 hrs by two fold serial microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 25, Issue:8 | Studies on antimicrobial effects of four ligands and their transition metal complexes with 8-mercaptoquinoline and pyridine terminal groups. |
| AID528739 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B516 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID544520 | Antibacterial activity against Escherichia coli K-12 W3110 infected in mouse assessed as increase of mouse survival at 30 ug, ip administered 15 mins and 12 hrs postinfection | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Variations in amino acid composition of antisense peptide-phosphorodiamidate morpholino oligomer affect potency against Escherichia coli in vitro and in vivo. |
| AID548473 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSn mutant gene after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID519657 | Antimicrobial activity against Escherichia coli EPI300 Irk1224 type 1 mutant harboring beta-lactamase CTX-M-3 gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID585199 | Antimicrobial activity against Escherichia coli DH5[alpha] transformed with pAC-ges1 plasmid encoding Beta-lactamase GES-5 E104, S170 mutant by Etest method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases. |
| AID1408108 | Antifungal activity against Candida albicans after 48 hrs by two-fold serial dilution method | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157 | Design, synthesis, antimicrobial, antiquorum-sensing and antitumor evaluation of new series of pyrazolopyridine derivatives. |
| AID565447 | Antimicrobial activity against Streptococcus intermedius SI006 biofilm harboring luxS mutant gene assessed as biofilm bacterial count at 0.04 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =413.7 +/- 24.47 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID775557 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus 3202 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21 | New derivatives of salicylamides: Preparation and antimicrobial activity against various bacterial species. |
| AID1551786 | Antibacterial activity against Clostridium tetani | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID379649 | Antibacterial activity against Staphylococcus aureus after 18 hrs by broth microdilution method | 2000 | Journal of natural products, Mar, Volume: 63, Issue:3 | Ganomycins A and B, new antimicrobial farnesyl hydroquinones from the basidiomycete Ganoderma pfeifferi. |
| AID530222 | Antimicrobial activity against Mycobacterium bovis BCG ML1046 carrying transposon IS1096::Km inserted at +33bp of bcg2743 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID278526 | Antimicrobial activity against Bifidobacterium infantis ATCC 15697 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID425593 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM605 in mouse J774A1 cells isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as intracellular killing of bacteria at 0.1 to 100 ug/ml af | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID1266800 | Antibacterial activity against Escherichia coli ATCC 35270 after 24 hrs at 37 degC by broth dilution method | 2015 | Journal of natural products, Nov-25, Volume: 78, Issue:11 | Meroterpenoids from a Tropical Dysidea sp. Sponge. |
| AID421836 | Antibacterial activity against Micrococcus luteus IFC 12708 | 2009 | Journal of natural products, Feb-27, Volume: 72, Issue:2 | Glionitrin A, an antibiotic-antitumor metabolite derived from competitive interaction between abandoned mine microbes. |
| AID1164940 | Antimicrobial activity against Mycobacterium tuberculosis H37Rv by microbroth dilution method | 2014 | Journal of medicinal chemistry, Oct-23, Volume: 57, Issue:20 | Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives. |
| AID1359447 | Antibacterial activity against Staphylococcus aureus NCIM 2010 after 12 hrs by serial dilution method | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | Antibacterial and anti-TB tat-peptidomimetics with improved efficacy and half-life. |
| AID1614661 | Bactericidal activity against stationary form of Escherichia coli assessed as reduction in colony forming units by fluorescent based time-kill assay | 2019 | Journal of medicinal chemistry, 02-28, Volume: 62, Issue:4 | Deciphering the Role of Intramolecular Networking in Cholic Acid-Peptide Conjugates on the Lipopolysaccharide Surface in Combating Gram-Negative Bacterial Infections. |
| AID530515 | Antimicrobial activity against group B Streptococcus sp. 'group B' isolate 6149-03 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID544013 | Antimicrobial activity against Pseudomonas putida isolate C231 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID1546103 | Antimicrobial activity against Proteus mirabilis after 24 hrs by agar disk diffusion method | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID614153 | Antimicrobial activity against Micrococcus luteus IFO 12708 | 2011 | Journal of natural products, Aug-26, Volume: 74, Issue:8 | Sesterterpenes from the tropical sponge Coscinoderma sp. |
| AID1412930 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 by microdilution method | 2018 | MedChemComm, May-01, Volume: 9, Issue:5 | Design, synthesis and antimicrobial activity of usnic acid derivatives. |
| AID69603 | Antibacterial activity against Escherichia coli | 2002 | Journal of medicinal chemistry, Sep-12, Volume: 45, Issue:19 | Inhibition of the antibacterial target UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC): isoxazoline zinc amidase inhibitors bearing diverse metal binding groups. |
| AID1433842 | Antifungal activity against Aspergillus fumigatus MTCC 3008 after 24 to 48 hrs by broth microdilution method | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs. |
| AID1585668 | Antibacterial activity against methicillin-resistant Staphylococcus epidermidis assessed as zone of inhibition at 10 ug/mL after 24 hrs by agar disc diffusion method | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Discovery of novel arylethenesulfonyl fluorides as potential candidates against methicillin-resistant of Staphylococcus aureus (MRSA) for overcoming multidrug resistance of bacterial infections. |
| AID574168 | Antibacterial activity against Escherichia coli MG1655 grown as biofilms after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID584768 | Antimicrobial activity against Acinetobacter lwoffii isolate G expressing beta-lactamase OXA-58 isolated from tracheal secretion of patient in presence of Sulbactam by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID526305 | Antimicrobial activity against Pseudomonas aeruginosa by agar plate disk diffusion method | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Bernthsen synthesis, antimicrobial activities and cytotoxicity of acridine derivatives. |
| AID405322 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae group I isolates with acrR ATT deletion behind nucleotide 170 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID587983 | Antibacterial activity against Escherichia coli AS226 carrying pBSDC69A mutant after 18 hrs by broth microdilution method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID456079 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID533380 | Antimicrobial activity against Bacteroides merdae assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID541857 | Antimicrobial activity against Escherichia coli ATCC 29522 carrying Edwardsiella ictaluri pM07-1 by microdilution assay | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | IncA/C plasmid-mediated florfenicol resistance in the catfish pathogen Edwardsiella ictaluri. |
| AID530205 | Antimicrobial activity against Mycobacterium bovis BCG ML1058 carrying transposon IS1096::Km inserted at +320bp of lprR gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1694058 | Antibacterial activity against Pseudomonas aeruginosa PAO1 assessed as reduction in bacterial growth incubated for 18 hrs by two-fold serial dilution method | 2021 | Bioorganic & medicinal chemistry, 02-01, Volume: 31 | Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study. |
| AID555261 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 103 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1700384 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as reduction in microbial growth after 18 hrs by agar dilution method | 2020 | Journal of natural products, 11-25, Volume: 83, Issue:11 | Total Syntheses of Prenylated Isoflavones from |
| AID425591 | Antibacterial activity against extracellular Escherichia coli isolate HM605 isolated from colonic mucosal biopsies of patient with Crohn's disease at 0.1 to 100 ug/ml after 3 hrs | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID541855 | Antimicrobial activity against Escherichia coli ATCC 29522 by microdilution assay | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | IncA/C plasmid-mediated florfenicol resistance in the catfish pathogen Edwardsiella ictaluri. |
| AID600684 | Bactericidal activity against Salmonella Typhimurium ATCC 13311 after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID1693217 | Anti-infective activity against Pseudomonas aeruginosa PAO1 assessed as reduction in bacterial growth by microdilution method | 2021 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 32 | 2-Aryl-3-(6-trifluoromethoxy)benzo[d]thiazole-based thiazolidinone hybrids as potential anti-infective agents: Synthesis, biological evaluation and molecular docking studies. |
| AID520993 | Antimicrobial activity against Bacillus anthracis Ames after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Novel antimicrobial peptides that exhibit activity against select agents and other drug resistant bacteria. |
| AID472402 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry, Apr-15, Volume: 18, Issue:8 | Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives. |
| AID1399498 | Bactericidal activity against Salmonella typhimurium ATCC 13311 by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID1769810 | Antimicrobial activity against Staphylococcus aureus CCAM 3090 assessed as inhibition of bacterial growth incubated for 16 to 18 hrs by broth micro dilution technique | |||
| AID324237 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoU mutant assessed as cell count in stationary phase at 100 ug/ml after 1 week | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID429367 | Antibacterial activity against Streptococcus pyogenes after 24 hrs by liquid dilution method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents. |
| AID447068 | Antibacterial activity against Mycobacterium smegmatis CCM 2067 at 10 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID1870158 | Antibacterial activity against wild type Staphylococcus aureus 4788/B assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID535677 | Antimicrobial activity against beta-lactamase positive Haemophilus influenzae expressing fst1 gene by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Genotypic versus phenotypic characterization, with respect to beta-lactam susceptibility, of Haemophilus influenzae isolates exhibiting decreased susceptibility to beta-lactam resistance markers. |
| AID371355 | Antibacterial activity against Salmonella Typhimurium ATCC 14028 after 24 hrs | 2009 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 19, Issue:3 | Synthesis and antimicrobial activities of halogenated bis(hydroxyphenyl)methanes. |
| AID559326 | Antimicrobial activity against Shigella sonnei assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID543792 | Antimicrobial activity against Acinetobacter baumannii VT 126 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID613775 | Antibacterial activity against multidrug-resistant Staphylococcus aureus 3SP/R33 after 18 hrs by serial broth microdilution method | 2011 | Bioorganic & medicinal chemistry, Aug-15, Volume: 19, Issue:16 | Novel benzofuroxan derivatives against multidrug-resistant Staphylococcus aureus strains: design using Topliss' decision tree, synthesis and biological assay. |
| AID478497 | Antibacterial activity against Pseudomonas aeruginosa at 2 mg/ml after 24 hrs by agar diffusion method | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5 | Synthesis and antimicrobial of new anthraquinone derivatives incorporating pyrazole moiety. |
| AID444050 | Fraction unbound in human plasma | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID529902 | Antimicrobial activity against Leptospira interrogans serovar Pomona isolate 12 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID1762801 | Antibacterial activity against vancomycin-resistant Enterococcus faecium assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | 2021 | Bioorganic & medicinal chemistry, 05-15, Volume: 38 | Dipyridyl-substituted thiosemicarbazone as a potent broad-spectrum inhibitor of metallo-β-lactamases. |
| AID644171 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID496396 | Antibacterial activity against azide-resistant Escherichia coli J53 SXT1 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID285203 | Antimicrobial activity against Escherichia coli M124 mutant with AG100 lon4::IS186 acrR::IS genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID548479 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm mutant gene after 24 hrs by Etest in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID1378893 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as diameter of inhibition zone at 100 uM after 24 hrs by cup diffusion method | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Synthesis, antimicrobial, DNA cleavage and antioxidant activities of tricyclic sultams derived from saccharin. |
| AID1411621 | Bactericidal activity against Micrococcus flavus ATCC 10240 incubated for 24 hrs followed by serial sub-cultivation and measured after 24 hrs by microdilution method | |||
| AID1293898 | Antibacterial activity against Escherichia coli after 18 hrs by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9 | Novel tetrazoloquinoline-rhodanine conjugates: Highly efficient synthesis and biological evaluation. |
| AID555262 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 103 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1916812 | Antibacterial activity against Bacillus subtilis NCIM 2079 assessed as bacterial growth inhibition incubated for 8 hrs by absorbance based assay | 2022 | European journal of medicinal chemistry, Aug-05, Volume: 238 | Recent contribution of medicinally active 2-aminothiophenes: A privileged scaffold for drug discovery. |
| AID1908128 | Antibacterial activity against NDM-1 expressing Escherichia coli ATCC BAA2469 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID287236 | Antimicrobial activity against Escherichia coli IFO 3301 at 100 ug/disc after 24 hrs | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles. |
| AID548476 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 after 24 hrs by Etest in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID85796 | The compound was tested in vivo for antibacterial activity against AmpR beta(-) Haemophilus influenza 351TO19 in mice after oral administration | 1999 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 9, Issue:21 | Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens. |
| AID395815 | Antibacterial activity against Escherichia coli ATCC 11303 at 300 ug/disk after 24 hrs by paper disk diffusion test | 2008 | European journal of medicinal chemistry, Nov, Volume: 43, Issue:11 | Synthesis and biological evaluation of diversely substituted indolin-2-ones. |
| AID510169 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID1896845 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 252 assessed as prevention of visible growth by broth microdilution method | |||
| AID532028 | Antimicrobial activity against Kluyvera georgiana 14751 expressing beta-lactamase CTX-M-78 obtained from bloodstream of patient by disk diffusion method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. |
| AID1505214 | Antibacterial activity in Escherichia coli clinical isolates endogenously expressing NDM1 incubated at 37 degC for 18 hrs by spectrophotometry | 2018 | ACS medicinal chemistry letters, Jan-11, Volume: 9, Issue:1 | Structure-Based Virtual Screening for the Discovery of Novel Inhibitors of New Delhi Metallo-β-lactamase-1. |
| AID547791 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237M mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID252635 | Bacterial susceptibility induced by D121 mutation in Escherichia coli OmpF | 2005 | Journal of medicinal chemistry, Mar-10, Volume: 48, Issue:5 | Beta-lactam screening by specific residues of the OmpF eyelet. |
| AID544058 | Antimicrobial activity against Shigella flexneri isolate C506 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID324230 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoU mutant assessed as cell count in log phase at 100 ug/ml after 5 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID529617 | Antibacterial activity against Beta-lactamase positive Haemophilus influenzae assessed as resistant isolates after 20 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID613615 | Antibacterial activity against 10'8 CFU/mL Aspergillus fumigatus MTCC 3008 by NCCLS M100-S12(M7) broth microdilution method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis and identification of β-aryloxyquinolines and their pyrano[3,2-c]chromene derivatives as a new class of antimicrobial and antituberculosis agents. |
| AID1402049 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 after 18 to 20 hrs by spectrophotometry based microdilution method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid. |
| AID487474 | Antibacterial activity against Staphylococcus aureus NCIM 2079; ATCC 6538P at 100 mg/ml after 24 hrs by agar cup plate method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Design, synthesis, characterization, and antibacterial activity of {5-chloro-2-[(3-substitutedphenyl-1,2,4-oxadiazol-5-yl)-methoxy]-phenyl}-(phenyl)-methanones. |
| AID543812 | Bactericidal activity against Streptococcus pyogenes VT 59 assessed as eradication of pre-formed biofilm at 50 times MIC after 24 hrs by serial dilution | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID425863 | Antimicrobial activity against Carnobacterium divergens CIP101029 at 0.5 McFarland inoculum size by E-test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens. |
| AID442417 | Antimicrobial activity against Micrococcus flavus at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID562221 | Antimicrobial activity against Desulfovibrio fairfieldensis by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID600676 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID266676 | Antibacterial activity against Escherichia coli | 2006 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 16, Issue:14 | Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives. |
| AID278529 | Antimicrobial activity against Bifidobacterium longum R0175 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID456076 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID293135 | Antimicrobial activity against Bacillus subtilis | 2007 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 17, Issue:3 | Design, synthesis, and evaluation of efflux substrate-metal chelator conjugates as potential antimicrobial agents. |
| AID1604669 | Antibacterial activity against Escherichia coli ATCC 25922 by visual method | |||
| AID607166 | Antimicrobial activity against Escherichia coli after 24 hrs by disc diffusion method | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14 | Exploration of antimicrobial and antioxidant potential of newly synthesized 2,3-disubstituted quinazoline-4(3H)-ones. |
| AID530215 | Antimicrobial activity against Mycobacterium bovis BCG ML1025 carrying transposon IS1096::Km inserted at +435bp of bcg3145 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1721971 | Antibacterial activity against Bacillus subtilis by microdilution method | 2020 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 30, Issue:17 | New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. |
| AID1767675 | Antibacterial activity against Serratia marcescens ATCC 13880 assessed as inhibition of bacterial growth incubated for 24 hrs by microdilution assay | 2021 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 47 | Antimicrobial, modulatory, and antibiofilm activity of tt-farnesol on bacterial and fungal strains of importance to human health. |
| AID565614 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.06 ug/ml (Rvb =798.3 +/- 37.09 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID206481 | The compound was tested for minimal inhibitory concentration against Staphylococcus aureus | 2002 | Bioorganic & medicinal chemistry letters, Sep-02, Volume: 12, Issue:17 | The activity of p-methoxybenzylisothiocyanate against Neisseria gonorrhoeae, Haemophilus ducreyi, and other microorganisms. |
| AID420206 | Antimicrobial activity against Escherichia coli UFPEDA 224 at 10 ug/disk after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID644173 | Antibacterial activity against Bacillus cereus clinical isolate treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID1428627 | Antimycobacterial activity against Mycobacterium smegmatis MC2 155 after 3 days by broth macrodilution method | 2017 | European journal of medicinal chemistry, Feb-15, Volume: 127 | Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis. |
| AID442407 | Antimicrobial activity against Listeria monocytogenes at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID735219 | Antimicrobial activity against Staphylococcus aureus MTCC 96 assessed as growth inhibition measured after overnight incubation by broth dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | New 2-benzylsulfanyl-nicotinic acid based 1,3,4-oxadiazoles: their synthesis and biological evaluation. |
| AID1266795 | Antibacterial activity against Staphylococcus aureus ATCC 6538p after 24 hrs at 37 degC by broth dilution method | 2015 | Journal of natural products, Nov-25, Volume: 78, Issue:11 | Meroterpenoids from a Tropical Dysidea sp. Sponge. |
| AID333996 | Antibacterial activity against Pseudomonas aeruginosa at 200 ug/100 uL after 24 hrs by tube broth dilution method | 1997 | Journal of natural products, Oct, Volume: 60, Issue:10 | New steroidal alkaloids from Buxus longifolia. |
| AID1399279 | Antimicrobial activity against Escherichia coli ATCC 35218 expressing TEM-1 beta lactamases after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID559696 | Antibacterial activity against Escherichia coli 3963 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | First report of plasmid-mediated quinolone resistance determinant qnrS1 in an Escherichia coli strain of animal origin in Italy. |
| AID278233 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-1 gyrA+ | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID587971 | Ratio of Kcat to Km for Escherichia coli beta-lactamase Toho-1 A237A mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID269645 | Antifungal activity against Candida albicans ATCC 10231 | 2006 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 16, Issue:16 | Lactones from a brown alga endophytic fungus (No. ZZF36) from the South China Sea and their antimicrobial activities. |
| AID289316 | Antifungal activity against Candida albicans ATCC 10145 after 48 hrs | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18 | Synthesis and antimicrobial activity of some new thiazolyl thiazolidine-2,4-dione derivatives. |
| AID426138 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by agar well diffusion method | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis and antimicrobial studies of novel methylene bridged benzisoxazolyl imidazo[2,1-b][1,3,4]thiadiazole derivatives. |
| AID584303 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus sciuri subsp. rodentium ATCC 700061T by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID585446 | Antimicrobial activity against ampG deficient Pseudomonas aeruginosa PAK harboring pUCP24 conferring resistance to gentamycin after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1287979 | Antibacterial activity against Staphylococcus aureus after 18 hrs by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 26, Issue:7 | Facile synthesis of 1,3-thiazolidin-4-ones as antitubercular agents. |
| AID396031 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate expressing pACYC184 plasmid by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID1382081 | Antibacterial activity against Pseudomonas aeruginosa ATCC 43288 after 18 to 24 hrs by double microdilution method | 2018 | European journal of medicinal chemistry, Feb-25, Volume: 146 | Ciprofloxacin derivatives and their antibacterial activities. |
| AID575418 | Antimicrobial activity against anrB-deficient Listeria monocytogenes EGD-e assessed as growth inhibition after 16 hrs by broth dilution method relative to wild type | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | The ABC transporter AnrAB contributes to the innate resistance of Listeria monocytogenes to nisin, bacitracin, and various beta-lactam antibiotics. |
| AID1104321 | Antibacterial activity against Staphylococcus aureus ATCC 6538 at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID1505215 | Antibacterial activity in Escherichia coli BL21 (DE3) expressing pET-24a-blaNDM-1 incubated at 37 degC for 18 hrs by spectrophotometry | 2018 | ACS medicinal chemistry letters, Jan-11, Volume: 9, Issue:1 | Structure-Based Virtual Screening for the Discovery of Novel Inhibitors of New Delhi Metallo-β-lactamase-1. |
| AID547183 | Antibacterial activity against Vibrio fluvialis assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID373670 | Antibacterial activity against Escherichia coli ATCC 25922 at 10 ug/disk after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID1593642 | Bactericidal activity against Escherichia coli NBRC 3301 incubated for 17 hrs followed by inoculums transfer to MHA plate and further incubated for 24 hrs | 2019 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 29, Issue:11 | Synthesis, antibacterial and cytotoxic evaluation of flavipucine and its derivatives. |
| AID585857 | Antimicrobial activity against Pseudomonas aeruginosa isolate 9 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID678537 | Antibacterial activity against Klebsiella pneumoniae ATCC 7761 | 2012 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 22, Issue:18 | Design, solvent free synthesis, and antimicrobial evaluation of 1,4 dihydropyridines. |
| AID519658 | Antimicrobial activity against Escherichia coli EPI300 Irk1224 type 2 mutant harboring beta-lactamase CTX-M-3 Ser167 mutant gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID278242 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-3 acrAB::Kan with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID562594 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecalis clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1697868 | Antimicrobial activity against Staphylococcus aureus ATCC 29737 assessed as zone of inhibition at 4 mg/ml incubated for 24 hrs by agar well diffusion method | |||
| AID1754161 | Antibacterial activity against Bacillus subtilis measured by broth microdilution method | 2021 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 43 | Synthesis and biological evaluation of novel benzo[a]pyridazino[3,4-c]phenazine derivatives. |
| AID1079946 | Presence of at least one case with successful reintroduction. [column 'REINT' in source] | |||
| AID1698869 | Antimicrobial activity against Bacillus subtilis subsp. spizizenii ATCC 6633 assessed as zone of inhibition at 2 mg/ml after 24 hrs by agar well diffusion method | 2020 | Journal of natural products, 10-23, Volume: 83, Issue:10 | Synthesis of Natural and Unnatural Quinolones Inhibiting the Growth and Motility of Bacteria. |
| AID360838 | Antibacterial activity against Staphylococcus aureus ATCC 27853 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID723712 | Bactericidal activity against Escherichia coli ATCC 35210 after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID381881 | Antibacterial activity against Staphylococcus epidermis after 24 hrs by broth microdilution method | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | Bioactive alkenylphenols from Piper obliquum. |
| AID426139 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by agar well diffusion method | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis and antimicrobial studies of novel methylene bridged benzisoxazolyl imidazo[2,1-b][1,3,4]thiadiazole derivatives. |
| AID477748 | Antimicrobial activity against Klebsiella pneumoniae after 24 hrs | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | An eco-friendly synthesis and antimicrobial activities of dihydro-2H-benzo- and naphtho-1,3-oxazine derivatives. |
| AID1730946 | Antibacterial activity against Escherichia coli MTCC 443 assessed as bacterial growth inhibition | 2021 | Bioorganic & medicinal chemistry letters, 03-15, Volume: 36 | Structure based design, synthesis, and biological evaluation of imidazole derivatives targeting dihydropteroate synthase enzyme. |
| AID585861 | Antimicrobial activity against Pseudomonas aeruginosa isolate 11 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID577210 | Antimicrobial activity against Escherichia coli C600::933W in stationary phase encoding Stx-2 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID555236 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 20 by Etest method in efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID583087 | Ratio of Kcat to Km for Escherichia coli XL1-Blue VIM-2 A64W mutant beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1287978 | Antibacterial activity against Pseudomonas after 18 hrs by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 26, Issue:7 | Facile synthesis of 1,3-thiazolidin-4-ones as antitubercular agents. |
| AID1577945 | Antimicrobial activity against Pseudomonas aeruginosa under iron-deficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID564890 | Antibacterial activity against ompF-deficient Escherichia coli AG100 harboring IS186 insertion in lon3 gene and Tn5 insertion in ycgE gene at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID1075972 | Antibacterial activity against Escherichia coli ATCC 25922 after 72 hrs by broth micro-dilution method | 2014 | European journal of medicinal chemistry, Mar-21, Volume: 75 | Toward new classes of potent antibiotics: synthesis and antimicrobial activity of novel metallosaldach-imidazolium salts. |
| AID1853148 | Antibacterial activity against Macrolide sensitive Streptococcus pneumoniae clinical isolate B0652 assessed as inhibition of bacterial growth incubated for 20 to 22 hrs by broth microdilution method | 2022 | RSC medicinal chemistry, Dec-14, Volume: 13, Issue:12 | Novel tetrahydropyrimidinyl-substituted benzimidazoles and benzothiazoles: synthesis, antibacterial activity, DNA interactions and ADME profiling. |
| AID623563 | Antibacterial activity against Staphylococcus aureus CGMCC1.2465 after 24 hrs by turbidimetric method | 2011 | Journal of natural products, Oct-28, Volume: 74, Issue:10 | Biologically active arborinane-type triterpenoids and anthraquinones from Rubia yunnanensis. |
| AID565430 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 biofilm assessed as biofilm bacterial count at 0.02 ug/ml (Rvb =402.9 +/- 26.88 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID424714 | Antibacterial activity against Pseudomonas aeruginosa at 1 ug/disk | 2009 | Journal of natural products, Apr, Volume: 72, Issue:4 | Limazepines A-F, pyrrolo[1,4]benzodiazepine Antibiotics from an Indonesian Micrococcus sp. |
| AID548018 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237D mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID383177 | Antimicrobial activity against Proteus vulgaris ATCC 3851 | 2008 | Journal of natural products, Apr, Volume: 71, Issue:4 | Sesterterpenoids from the sponge Sarcotragus sp. |
| AID442405 | Antimicrobial activity against Enterobacter cloacae at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1653050 | Antibacterial activity against Proteus vulgaris | 2019 | European journal of medicinal chemistry, Feb-15, Volume: 164 | Isatin derivatives and their anti-bacterial activities. |
| AID530212 | Antimicrobial activity against Mycobacterium bovis BCG ML1013 carrying transposon IS1096::Km inserted at +923bp of cpsY gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1079941 | Liver damage due to vascular disease: peliosis hepatitis, hepatic veno-occlusive disease, Budd-Chiari syndrome. Value is number of references indexed. [column 'VASC' in source] | |||
| AID511057 | Antibacterial activity against Pseudomonas aeruginosa MTCC 2488 by broth microdilution method | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Pharmacological evaluation and characterizations of newly synthesized 1,2,4-triazoles. |
| AID555224 | Ratio of Kcat to Km for Acinetobacter genomosp. 3 isolate 65 ADC-14 | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1759338 | Antibacterial activity against Pseudomonas aeruginosa MTCC 424 assessed as bacterial growth inhibition by microdilution method | 2021 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 41 | Design and synthesis, biological evaluation of bis-(1,2,3- and 1,2,4)-triazole derivatives as potential antimicrobial and antifungal agents. |
| AID442413 | Antimicrobial activity against Enterobacter cloacae at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1616518 | Antibacterial activity against Escherichia coli after 24 hrs by broth microdilution method | 2019 | Journal of natural products, 10-25, Volume: 82, Issue:10 | Highly Oxygenated Triterpenoids and Rare Tetraterpenoids from |
| AID613776 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus VISA3 at 2 times MIC of multidrug-resistant Staphylococcus aureus 3SP/R33 after 18 hrs by serial broth microdilution method | 2011 | Bioorganic & medicinal chemistry, Aug-15, Volume: 19, Issue:16 | Novel benzofuroxan derivatives against multidrug-resistant Staphylococcus aureus strains: design using Topliss' decision tree, synthesis and biological assay. |
| AID547174 | Antibacterial activity against Vibrio cholerae assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID625280 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID1286502 | Ratio of MBC for methicillin-sensitive Staphylococcus aureus ATCC 6538 to MIC90 for methicillin-sensitive Staphylococcus aureus ATCC 6538 | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID429370 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by liquid dilution method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents. |
| AID1158654 | Antibacterial activity against Bacillus subtilis grown in sheep blood agar media assessed as concentration required to inhibit bacterial growth due to absence of hemolysis of erythrocytes after 18 hrs by ten-fold broth dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Eremophilane-type sesquiterpenoids with diverse skeletons from Ligularia sagitta. |
| AID1535445 | Anti-biofilm activity against Pseudoalteromonas lipolytica TC8 assessed as bacterial adhesion at 200 uM incubated for 15 hrs at 20 degC by Syto 61 dye based fluorimetric assay relative to control | 2019 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 29, Issue:4 | Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds? |
| AID164572 | The compound was tested for minimal inhibitory concentration against Pseudomonas aeruginosa | 2002 | Bioorganic & medicinal chemistry letters, Sep-02, Volume: 12, Issue:17 | The activity of p-methoxybenzylisothiocyanate against Neisseria gonorrhoeae, Haemophilus ducreyi, and other microorganisms. |
| AID775959 | Antibacterial activity against Proteus vulgaris ATCC 13315 assessed as growth inhibition at 100 ug/mL after 18 to 24 hrs by microdilution assay | 2013 | European journal of medicinal chemistry, Nov, Volume: 69 | Synthesis, antibacterial and antioxidant activities of new 1-alkyl-4-(1-alkyl-4-oxo-1,4-dihydroquinolin-2-yl)pyridinium bromides. |
| AID447589 | Antibacterial activity against Bacillus subtilis ATCC 6633 at 100 ug/ml after 24 hrs by agar cup plate method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and antibacterial activity of 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-pyrazol-4-yl]-5-(substituted-phenyl)-[1,3,4]oxadiazoles. |
| AID523269 | Binding affinity to Escherichia coli isolate HN1157 AcrAB-TolC efflux transporter | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Kinetic parameters of efflux of penicillins by the multidrug efflux transporter AcrAB-TolC of Escherichia coli. |
| AID584774 | Antimicrobial activity against Acinetobacter lwoffii isolate M expressing beta-lactamase OXA-58 isolated from tracheal secretion of patient in presence of Sulbactam by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID545448 | Antimicrobial activity against extended-spectrum beta-lactamase-negative Klebsiella pneumoniae assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID419331 | Antibacterial activity against Bacillus subtilis MTCC 121 at 200 ug/ml after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis and evaluation of some new benzimidazole derivatives as potential antimicrobial agents. |
| AID287376 | Antibacterial activity against Proteus vulgaris after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID539561 | Antimicrobial activity against Escherichia coli ATCC 25922 | 2010 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 20, Issue:23 | Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase. |
| AID548005 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237P mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID1419478 | Antimicrobial activity against Candida albicans by two fold serial dilution method | 2017 | European journal of medicinal chemistry, May-05, Volume: 131 | Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents. |
| AID1535453 | Growth inhibition of Pseudoalteromonas ulvae TC14 at 5 uM measured every hr for 6 hrs by turbidimetric method | 2019 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 29, Issue:4 | Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds? |
| AID763999 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 assessed as diameter of inhibition zone at 1 mg/ml after 24 hrs by cup diffusion method (Rvb = 16 mm) | 2013 | European journal of medicinal chemistry, Aug, Volume: 66 | Synthesis, biological evaluation and molecular docking studies of some pyrimidine derivatives. |
| AID510747 | Antibacterial activity against Escherichia coli AG102MB harboring pSport1-based acrB gene | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy. |
| AID477028 | Antibacterial activity against Bacillus thuringiensis at 2 mg/ml after 24 hrs by agar diffusion assay | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activities of some new thiazole and pyrazole derivatives based on 4,5,6,7-tetrahydrobenzothiophene moiety. |
| AID561444 | Antibacterial activity against Escherichia coli DH10B harboring plasmid BCSK carrying beta-lactamase CMY-33 gene by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Reduced susceptibility to cefepime among Escherichia coli clinical isolates producing novel variants of CMY-2 beta-lactamase. |
| AID244823 | Minimal inhibitory concentration against Bacillus cereus | 2004 | Bioorganic & medicinal chemistry letters, Dec-06, Volume: 14, Issue:23 | Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: a structure-activity evaluation study. |
| AID1577961 | Antimicrobial activity against Klebsiella pneumoniae X68 under iron-deficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID1501340 | Antibacterial activity against Micrococcus luteus KCCM 11548 assessed as zone of inhibition at 10 microg/disk after 18 to 36 hrs by agar diffusion method | 2017 | Journal of natural products, 09-22, Volume: 80, Issue:9 | Gordonic Acid, a Polyketide Glycoside Derived from Bacterial Coculture of Streptomyces and Gordonia Species. |
| AID419337 | Antibacterial activity against Escherichia coli ATCC 25922 at 200 ug/ml after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis and evaluation of some new benzimidazole derivatives as potential antimicrobial agents. |
| AID527629 | Antimicrobial activity against Staphylococcus aureus ATCC 6538p after 24 hrs by broth dilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Bromophenols as Candida albicans isocitrate lyase inhibitors. |
| AID1399496 | Bactericidal activity against Micrococcus flavus ATCC 10240 by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID562224 | Antimicrobial activity against Desulfovibrio piger by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID1706155 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as reduction in bacterial growth incubated for 18 hrs by CLSI based broth microdilution assay | |||
| AID294964 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID559905 | Antimicrobial activity against Escherichia coli DH5alpha by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | First detection of plasmid-encoded blaOXY beta-lactamase. |
| AID1652708 | Induction of Escherichia coli K12 MG1655 recN promotor measured at 30 mins interval for 20 hrs by fluorescence assay relative to control | |||
| AID546620 | Antimicrobial activity against Escherichia coli harboring beta-lactamase VIM-2 by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). |
| AID1141107 | Antimicrobial activity against Klebsiella pneumoniae ATCC 700603 at 128 uM after 24 to 48 hrs by two-fold broth microdilution method | 2014 | Bioorganic & medicinal chemistry, May-15, Volume: 22, Issue:10 | Exploring 5-nitrofuran derivatives against nosocomial pathogens: synthesis, antimicrobial activity and chemometric analysis. |
| AID520720 | Antibacterial activity against Escherichia coli DH10B in presence of 4 ug/ml clavulanic acid | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID573347 | Antibacterial activity against ceftazidime-susceptible Enterobacter cloacae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID520708 | Antibacterial activity against Acinetobacter baumannii phenotype 2 by disk diffusion method in presence of 4 ug/ml clavulanic acid | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID1379744 | Antimicrobial activity against Escherichia coli incubated for 24 hrs by disc diffusion assay | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of cyclopenta(hepta)[b]thiophene and fused cyclohepta[b]thiophene analogs. |
| AID530210 | Antimicrobial activity against Mycobacterium bovis BCG ML1047 carrying transposon IS1096::Km inserted at +544bp of fadD23 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1423477 | Antibacterial activity against Acinetobacter baumannii ATCC 19606 after 24 hrs by bacterial proliferation assay | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID400381 | Antibacterial activity against Pseudomonas aeruginosa at 200 ug/100uL after 24 hrs by agar well diffusion method | 1998 | Journal of natural products, Feb, Volume: 61, Issue:2 | Antibacterial steroidal alkaloids from Sarcococca saligna. |
| AID509701 | Antibacterial activity against Staphylococcus aureus after 24 hrs by tube dilution method | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Synthesis of some 3-substituted amino-4,5-tetramethylene thieno[2,3-d][ 1,2,3]-triazin-4(3H)-ones as potential antimicrobial agents. |
| AID1233739 | Antimicrobial activity against Streptococcus pyogenes 345/1 assessed as microbial growth inhibition at 1 mg/ml incubated overnight at 37 degC | 2015 | Journal of natural products, Jul-24, Volume: 78, Issue:7 | HPLC-NMR and HPLC-MS Profiling and Bioassay-Guided Identification of Secondary Metabolites from the Australian Plant Haemodorum spicatum. |
| AID540837 | Antimicrobial activity against Salmonella enterica serovar enteritidis isolate 5408 harboring gyrA D87Y mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID546951 | Antibacterial activity against Shigella flexneri by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID530218 | Antimicrobial activity against Mycobacterium bovis BCG ML1030 carrying transposon IS1096::Km inserted at +849bp of bcg1988c gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID324177 | Antibacterial activity against Escherichia coli K12 mutant JHU313 at 1.5 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID531614 | Antimicrobial activity against Escherichia coli JM109 by agar dilution method in presence of Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae. |
| AID559898 | Antimicrobial activity against Klebsiella oxytoca KO281 harboring beta-lactamase OXY-1 and CMY-2 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | First detection of plasmid-encoded blaOXY beta-lactamase. |
| AID582895 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87R mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID530221 | Antimicrobial activity against Mycobacterium bovis BCG ML1038 carrying transposon IS1096::Km inserted at +78bp of bcg2735 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID536080 | Antimicrobial activity against Micrococcus luteus IFO 3232 at 100 ug/8 mm disk after 24 hrs by agar disk diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID405321 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae group IIc isolates with acrR TTA>TGA mutation at 521 position by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID535745 | Antimicrobial activity against community-acquired Klebsiella pneumoniae expressing extended spectrum beta-lactamase obtained from patient with intra-abdominal infection assessed as susceptible isolates by EUCAST method in presence of beta-lactamase inhibi | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Incidence and antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae with extended-spectrum beta-lactamases in community- and hospital-associated intra-abdominal infections in Europe: results of the 2008 Study for Monitoring Antimicrob |
| AID278249 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS1 gyrA+ with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1852771 | Drug uptake in Pseudomonas aeruginosa ATCC 9027 assessed as drug accumulation across outer membrane | 2022 | RSC medicinal chemistry, Sep-21, Volume: 13, Issue:9 | Design and evaluation of poly-nitrogenous adjuvants capable of potentiating antibiotics in Gram-negative bacteria. |
| AID1202846 | Antimicrobial activity against Bacillus cereus at 10 ug/disc by disc diffusion assay | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Puupehenol, a potent antioxidant antimicrobial meroterpenoid from a Hawaiian deep-water Dactylospongia sp. sponge. |
| AID478499 | Antifungal activity against Fusarium solani at 2 mg/ml after 7 days by agar diffusion method | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5 | Synthesis and antimicrobial of new anthraquinone derivatives incorporating pyrazole moiety. |
| AID1374419 | Antibacterial activity against Aeromonas hydrophila ATCC 95080 | 2018 | Bioorganic & medicinal chemistry letters, 03-01, Volume: 28, Issue:5 | Synthesis, antimicrobial activity and acid dissociation constants of methyl 5,5-diphenyl-1-(thiazol-2-yl)pyrrolidine-2-carboxylate derivatives. |
| AID1585548 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Benzofuran derivatives and their anti-tubercular, anti-bacterial activities. |
| AID1762805 | Antibacterial activity against against Escherichia coli 06 assessed as reduction in bacterial growth incubated for 24 hrs by broth microdilution method | 2021 | Bioorganic & medicinal chemistry, 05-15, Volume: 38 | Dipyridyl-substituted thiosemicarbazone as a potent broad-spectrum inhibitor of metallo-β-lactamases. |
| AID528536 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B514 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID278556 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium pseudolongum ATCC 25562 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1266798 | Antibacterial activity against Salmonella enterica ATCC 14028 after 24 hrs at 37 degC by broth dilution method | 2015 | Journal of natural products, Nov-25, Volume: 78, Issue:11 | Meroterpenoids from a Tropical Dysidea sp. Sponge. |
| AID1695862 | Antibacterial activity against Escherichia coli NCIM 2256 incubated for 24 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID555214 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 243 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID600673 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID85784 | In vitro inhibitory activity against Haemophilus AmpR (37) | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID568667 | Antimicrobial activity against Branhamella catarrhalis assessed as growth inhibition at 10 ug/ml by agar dilution method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and structure-activity relationship of 2-thiopyrimidine-4-one analogs as antimicrobial and anticancer agents. |
| AID1079932 | Highest frequency of moderate liver toxicity observed during clinical trials, expressed as a percentage. [column '% BIOL' in source] | |||
| AID735980 | Antimicrobial activity against Fusarium oxysporum at 1 mg/mL after 48 hrs by agar disc diffusion method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Synthesis and antimicrobial activity of some new benzo and naphthonitrile derivatives. |
| AID1767667 | Antibacterial activity against Streptococcus mutans ATCC 25175 assessed as inhibition of bacterial growth incubated for 24 hrs by microdilution assay | 2021 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 47 | Antimicrobial, modulatory, and antibiofilm activity of tt-farnesol on bacterial and fungal strains of importance to human health. |
| AID1462725 | Antimicrobial activity against Aspergillus clavatus MTCC 1323 | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20 | Benzothiazole analogues: Synthesis, characterization, MO calculations with PM6 and DFT, in silico studies and in vitro antimalarial as DHFR inhibitors and antimicrobial activities. |
| AID600675 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID1827146 | Antibacterial activity against methicillin-resistant Staphylococcus aureus COL assessed as inhibition of bacterial growth after 18 hrs in presence of oxacillin by CLSI protocol based broth microdilution assay | 2022 | ACS medicinal chemistry letters, Mar-10, Volume: 13, Issue:3 | Identification and Evaluation of Brominated Carbazoles as a Novel Antibiotic Adjuvant Scaffold in MRSA. |
| AID529306 | Antimicrobial activity against Acinetobacter baumannii isolate Ac058 expressing beta-lactamase Oxa-58 by broth microdilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate. |
| AID400383 | Antibacterial activity against Streptococcus pyogenes at 200 ug/100uL after 24 hrs by agar well diffusion method | 1998 | Journal of natural products, Feb, Volume: 61, Issue:2 | Antibacterial steroidal alkaloids from Sarcococca saligna. |
| AID535638 | Antimicrobial activity against Group B streptococcus serotype VI R2 harboring F395L, V405A, R433H, H438Y, and G648A mutations in PBP 2X and T567I mutation in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID562932 | Antimicrobial activity against Clostridium difficile 6425 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID534941 | Antimicrobial activity against Fusobacterium nucleatum by Wadsworth agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Study of the in vitro activities of rifaximin and comparator agents against 536 anaerobic intestinal bacteria from the perspective of potential utility in pathology involving bowel flora. |
| AID752005 | Antibacterial activity against Escherichia coli NCIM 2256 by broth dilution method | 2013 | Bioorganic & medicinal chemistry letters, May-01, Volume: 23, Issue:9 | Green synthesis of tetrahydropyrimidine analogues and evaluation of their antimicrobial activity. |
| AID557954 | Antimicrobial activity in Actinomyces by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1474809 | Antibacterial activity against Bacillus subtilis NBRC 13719 after overnight incubation by microdilution method | 2017 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 27, Issue:11 | Syntheses of benzophenone-xanthone hybrid polyketides and their antibacterial activities. |
| AID324290 | Antibacterial activity against Escherichia coli K12 containing deletion deltahipA mutant assessed as cell count in log phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID279561 | Antimicrobial activity against Haemophilus influenzae BLNAS strains | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Diversity of ampicillin resistance genes and antimicrobial susceptibility patterns in Haemophilus influenzae strains isolated in Korea. |
| AID495327 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with Asp350Asn, Met377Ile, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID745306 | Antibacterial activity against Streptococcus pneumoniae MTCC 1936 assessed as growth inhibition after overnight incubation by NCCLS broth microdilution method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Synthesis and identification of β-aryloxyquinoline based diversely fluorine substituted N-aryl quinolone derivatives as a new class of antimicrobial, antituberculosis and antioxidant agents. |
| AID285197 | Antimicrobial activity against Escherichia coli M083 mutant with AG100 lon4::IS186 acrR::IS1 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID1374420 | Antibacterial activity against Escherichia coli | 2018 | Bioorganic & medicinal chemistry letters, 03-01, Volume: 28, Issue:5 | Synthesis, antimicrobial activity and acid dissociation constants of methyl 5,5-diphenyl-1-(thiazol-2-yl)pyrrolidine-2-carboxylate derivatives. |
| AID662990 | Antibacterial activity against Salmonella typhi MTCC 98 by macrobroth dilution assay | 2012 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 22, Issue:12 | An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidines. |
| AID1546100 | Antimicrobial activity against Escherichia coli after 24 hrs by agar disk diffusion method | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID447065 | Antibacterial activity against Bacillus cereus ATCC 7064 at 10 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID582907 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87F mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID555263 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 103 by Etest method in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID678546 | Antibacterial activity against ampicillin-resistant Klebsiella pneumoniae clinical isolate | 2012 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 22, Issue:18 | Design, solvent free synthesis, and antimicrobial evaluation of 1,4 dihydropyridines. |
| AID1546115 | Antifungal activity against Candida glabrata | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID1501341 | Antibacterial activity against Enterococcus hirae KCCM 11768 assessed as zone of inhibition at 10 microg/disk after 18 to 36 hrs by agar diffusion method | 2017 | Journal of natural products, 09-22, Volume: 80, Issue:9 | Gordonic Acid, a Polyketide Glycoside Derived from Bacterial Coculture of Streptomyces and Gordonia Species. |
| AID587969 | Ratio of Kcat to Km for Escherichia coli beta-lactamase Toho-1 N104A mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID1652706 | Induction of Escherichia coli K12 MG1655 recA promotor measured at 30 mins interval for 20 hrs by fluorescence assay relative to control | |||
| AID555464 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 90 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID528533 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B502 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID665057 | Antibacterial activity against Clostridium tetani MTCC 449 after 24 hrs by micro-broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 22, Issue:11 | An efficient one-pot synthesis, structure, antimicrobial and antioxidant investigations of some novel quinolyldibenzo[b,e][1,4]diazepinones. |
| AID441923 | Antibacterial activity against Pseudomonas aeruginosa H45006 after 24 hrs by NCCLS method | 2009 | Journal of medicinal chemistry, Nov-12, Volume: 52, Issue:21 | Coordination chemistry based approach to lipophilic inhibitors of 1-deoxy-D-xylulose-5-phosphate reductoisomerase. |
| AID565010 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus haemolyticus assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID318713 | Antimicrobial activity against Streptococcus faecalis by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID1193887 | Antimicrobial activity against Escherichia coli MTCC 4351 after 24 hrs by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Rapid 'one-pot' synthesis of a novel benzimidazole-5-carboxylate and its hydrazone derivatives as potential anti-inflammatory and antimicrobial agents. |
| AID330984 | Antimicrobial activity against Staphylococcus aureus 29213 | 2007 | Nature, May-03, Volume: 447, Issue:7140 | PTC124 targets genetic disorders caused by nonsense mutations. |
| AID1423478 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 after 24 hrs by bacterial proliferation assay | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID520990 | Antimicrobial activity against Brucella melitensis 16 M after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Novel antimicrobial peptides that exhibit activity against select agents and other drug resistant bacteria. |
| AID112356 | In Vivo evaluation for its effective dose against Haemophilus influenzae (351GR1) | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID577393 | Antimicrobial activity against Escherichia coli O157:H7 185 encoding stx gene by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID285511 | Antibacterial activity against Enterobacter sp. | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens. |
| AID304976 | Antifungal activity against Aspergillus fumigatus by broth micro-dilution technique | 2007 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1 | New antifungal flavonoid glycoside from Vitex negundo. |
| AID276384 | Antibacterial activity against Klebsiella pneumoniae by broth microdilution technique | 2006 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 16, Issue:22 | Naphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: synthesis and biological evaluation as potential antibacterial and antifungal agents. |
| AID436287 | Antibacterial activity against Salmonella Typhimurium ATCC 14028 after 24 hrs by two-fold dilution method | 2008 | Journal of natural products, Nov, Volume: 71, Issue:11 | Scalarane sesterterpenes from the sponge Smenospongia sp. |
| AID1471040 | Growth inhibition of Staphylococcus aureus NCIM 2602 at 10 ug/ml measured after 12 hrs relative to control | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID1331869 | Antibacterial activity against Bacillus subtilis 168 | 2017 | Bioorganic & medicinal chemistry, 01-01, Volume: 25, Issue:1 | Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. |
| AID547175 | Antibacterial activity against Vibrio cholerae assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID330982 | Antimicrobial activity against Escherichia coli BAS849 | 2007 | Nature, May-03, Volume: 447, Issue:7140 | PTC124 targets genetic disorders caused by nonsense mutations. |
| AID520717 | Antibacterial activity against Acinetobacter baumannii CIP7010 harboring pOXA-97 by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID558534 | Antibacterial activity against bla gene-positive and nitrocefin reaction-negative beta-lactamase harboring Campylobacter jejuni isolate P1699 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID360850 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID644164 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID1055631 | Antibacterial activity against Staphylococcus aureus MTCC 96 assessed as growth inhibition after 24 hrs by broth microdilution method | 2013 | European journal of medicinal chemistry, , Volume: 70 | Synthesis and antimicrobial activity of some novel hydrazide, benzochromenone, dihydropyridine, pyrrole, thiazole and thiophene derivatives. |
| AID1877438 | Antibacterial activity against Pseudomonas aeruginosa | 2022 | Bioorganic & medicinal chemistry letters, 01-01, Volume: 55 | New bis- and tetrakis-1,2,3-triazole derivatives: Synthesis, DNA cleavage, molecular docking, antimicrobial, antioxidant activity and acid dissociation constants. |
| AID678536 | Antibacterial activity against Citrobacter koseri ATCC 27028 | 2012 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 22, Issue:18 | Design, solvent free synthesis, and antimicrobial evaluation of 1,4 dihydropyridines. |
| AID633490 | Antibacterial activity against Proteus vulgaris ATCC 3851 after 24 hrs by two fold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial activity of brominated resorcinol dimers. |
| AID532989 | Antibacterial activity against Klebsiella aerogenes NCIM 2281 in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID582921 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61L mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1551858 | Antibacterial activity against Escherichia coli | 2019 | European journal of medicinal chemistry, Jul-15, Volume: 174 | 1,2,4-Triazole-quinoline/quinolone hybrids as potential anti-bacterial agents. |
| AID577209 | Antimicrobial activity against Escherichia coli C600::933W in logarithmic phase encoding Stx-2 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID429265 | Antibacterial activity against Streptococcus pyogenes at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents. |
| AID495748 | Antimicrobial activity against Escherichia coli ATCC 25922 by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID456080 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID1585550 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Benzofuran derivatives and their anti-tubercular, anti-bacterial activities. |
| AID1596683 | Bactericidal activity against Escherichia coli ATCC 35210 incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID587195 | Antimicrobial activity against Pseudomonas fluorescens after 18 hrs by broth microdilution method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Comazaphilones A-F, azaphilone derivatives from the marine sediment-derived fungus Penicillium commune QSD-17. |
| AID671473 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 49476 after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Aug-01, Volume: 20, Issue:15 | Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. |
| AID245368 | Minimum inhibitory concentration required for antibacterial activity against Pseudomonas diminuta MTCC 3361; gram negative | 2004 | Bioorganic & medicinal chemistry letters, Aug-16, Volume: 14, Issue:16 | Synthesis and QSAR studies of pyrimido[4,5-d]pyrimidine-2,5-dione derivatives as potential antimicrobial agents. |
| AID585421 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W322-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID360066 | Inhibition of Enterococcus faecium M512 LDtfm transpeptidase activity assessed as tri-aspartate-tri-aspartate-tetra-aspartate multimer containing L-Lys3 to D-Asp-L-Lys3 cross links at 8 ug/ml | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID360844 | Antibacterial activity against Escherichia coli ATCC 25922 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID584763 | Antimicrobial activity against Acinetobacter lwoffii isolate B expressing beta-lactamase OXA-164 isolated from tracheal secretion of patient in presence of Sulbactam by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID587976 | Ratio of Kcat to Km for Escherichia coli beta-lactamase Toho-1 G232A mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID548037 | Antimicrobial activity against Escherichia coli DH10B by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID595275 | Antimicrobial activity against Escherichia coli at 1 mg/ml after 24 hrs by agar well diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Applications of 2-arylhydrazononitriles in synthesis: preparation of new indole containing 1,2,3-triazole, pyrazole and pyrazolo[1,5-a]pyrimidine derivatives and evaluation of their antimicrobial activities. |
| AID529584 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-1 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID727798 | Antimicrobial activity against Escherichia coli DH10B by CLSI agar dilution method | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3 | Design and exploration of novel boronic acid inhibitors reveals important interactions with a clavulanic acid-resistant sulfhydryl-variable (SHV) β-lactamase. |
| AID1657463 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by CLSI based susceptibility test method | 2020 | Journal of natural products, 04-24, Volume: 83, Issue:4 | Proximicins F and G and Diproximicin A: Aminofurans from the Marine-Derived |
| AID533126 | Antimicrobial activity against Bacteroides caccae assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID582763 | Antimicrobial activity against eaeA positive verocytotoxin-producing non-O157 Escherichia coli isolates obtained from human assessed as percentage of resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID662077 | Antibacterial activity against Staphylococcus aureus after 20 hrs by liquid growth inhibition assay | 2012 | Journal of medicinal chemistry, Mar-08, Volume: 55, Issue:5 | From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity. |
| AID1504232 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by two fold serial dilution method | 2017 | Journal of natural products, 11-22, Volume: 80, Issue:11 | Nicrophorusamides A and B, Antibacterial Chlorinated Cyclic Peptides from a Gut Bacterium of the Carrion Beetle Nicrophorus concolor. |
| AID444054 | Oral bioavailability in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID422498 | Ratio of Kcat to Km of Carnobacterium divergens BM4489 penicillinase Cad-1 relative to benzyl-penicillin | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens. |
| AID565059 | Antibacterial activity against wild-type Escherichia coli AG100 harboring IS186 insertion in lon3 gene at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID1767661 | Antibacterial activity against Enterococcus faecalis ATCC 6569 assessed as inhibition of bacterial growth incubated for 24 hrs by microdilution assay | 2021 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 47 | Antimicrobial, modulatory, and antibiofilm activity of tt-farnesol on bacterial and fungal strains of importance to human health. |
| AID1774194 | Antibacterial activity against Escherichia coli delta tonB assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID564888 | Antibacterial activity against wild-type Escherichia coli AG100 harboring IS186 insertion in lon3 gene, Tn5 insertion in ycgE gene and plasmid pMPM at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID1322100 | Antimicrobial activity against Escherichia coli ATCC 25922 after 24 hrs by broth microdilution assay | 2016 | Bioorganic & medicinal chemistry, 11-01, Volume: 24, Issue:21 | Synthesis, characterization, and evaluation of (E)-methyl 2-((2-oxonaphthalen-1(2H)-ylidene)methylamino)acetate as a biological agent and an anion sensor. |
| AID372564 | Antibacterial activity against genetically beta-lactamase-negative ampicillin-resistant Haemophilus influenzae type b with bla gene but without an amino acid substitution in ftsI gene assessed as resistance rate by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID405326 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae group IIa isolates with acrR aminoacid substitution mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID529588 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-10 assessed as bacterial density at 512 ug/ml after 18 hrs | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID395353 | Antibacterial activity against Proteus vulgaris ATCC 8427 at 1 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID383172 | Antimicrobial activity against Micrococcus luteus IFC12708 | 2008 | Journal of natural products, Apr, Volume: 71, Issue:4 | Sesterterpenoids from the sponge Sarcotragus sp. |
| AID285192 | Antimicrobial activity against Escherichia coli M043 mutant with AG100 lon4::IS186 marR::IS2 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID287238 | Antimicrobial activity against Candida albicans IFO 0583 at 100 ug/disc after 48 hrs | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles. |
| AID409952 | Inhibition of human brain MAOB | 2008 | Journal of medicinal chemistry, Nov-13, Volume: 51, Issue:21 | Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. |
| AID584326 | Antibacterial activity against tolC deficient Escherichia coli GD100 | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Interplay between drug efflux and antioxidants in Escherichia coli resistance to antibiotics. |
| AID555446 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 195 by Etest method in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID547761 | Antimicrobial activity against Klebsiella pneumoniae 1534 expressing beta-lactamase KPC-2 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID529598 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-12 assessed as inhibition of bacterial growth at 4096 ug/ml after 18 hrs | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID389003 | Antibacterial activity against Staphylococcus aureus ATCC 6538 assessed as diameter of the inhibition zone at 1 uM/disk after 4 hrs by disk diffusion method | 2008 | Bioorganic & medicinal chemistry, Dec-01, Volume: 16, Issue:23 | Hetero-Diels-Alder reaction of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with arylsulfonylcyanides. Synthesis and antimicrobial activity of 4-hydroxy-2-(arylsulfonyl)pyridines. |
| AID555473 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 128 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1384551 | Inhibition of Acinetobacter baumannii PBP1b transglycosylase activity using NBD-lipid 2 as substrate after 2 hrs by muramidase enzyme coupled HPLC analysis | 2018 | European journal of medicinal chemistry, Apr-25, Volume: 150 | Structure-based design of bacterial transglycosylase inhibitors incorporating biphenyl, amine linker and 2-alkoxy-3-phosphorylpropanoate moieties. |
| AID1504826 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 after 24 hrs by broth microdilution method | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12 | Sulfur-Containing Aristoloxazines and Other Constituents of the Roots of Aristolochia orbicularis. |
| AID1653051 | Antibacterial activity against Klebsiella pneumoniae | 2019 | European journal of medicinal chemistry, Feb-15, Volume: 164 | Isatin derivatives and their anti-bacterial activities. |
| AID419332 | Antibacterial activity against Bacillus subtilis MTCC 121 at 500 ug/ml after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis and evaluation of some new benzimidazole derivatives as potential antimicrobial agents. |
| AID1486827 | Antimicrobial activity against Streptococcus pyogenes MTCC 442 incubated for overnight by broth micro dilution method | 2017 | Bioorganic & medicinal chemistry, 08-01, Volume: 25, Issue:15 | 1,2,4-Triazole and 1,3,4-oxadiazole analogues: Synthesis, MO studies, in silico molecular docking studies, antimalarial as DHFR inhibitor and antimicrobial activities. |
| AID1132056 | Antiviral activity against influenza A virus NWS/H0N1 infected in BHK cells by agar diffusion assay | 1978 | Journal of medicinal chemistry, Jan, Volume: 21, Issue:1 | Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. |
| AID245339 | Minimum inhibitory concentration required for antibacterial activity against Escherichia coli ATCC 13607; gram negative | 2004 | Bioorganic & medicinal chemistry letters, Aug-16, Volume: 14, Issue:16 | Synthesis and QSAR studies of pyrimido[4,5-d]pyrimidine-2,5-dione derivatives as potential antimicrobial agents. |
| AID324232 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 assessed as cell count in log phase at 100 ug/ml after 1 week | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID467963 | Antimicrobial activity against Citrobacter freundii ATCC 8090 after 18 to 24 hrs by liquid broth method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. |
| AID1546087 | Antimicrobial activity against Escherichia coli | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID1471043 | Growth inhibition of Bacillus subtilis NCIM 2162 at 10 ug/ml measured after 12 hrs relative to control | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID1114822 | Antibacterial activity against Yersinia pseudotuberculosis ATCC 911 after 18 to 24 hr by double microdilution method | 2013 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, Aug, Volume: 22, Issue:8 | |
| AID540825 | Antimicrobial activity against acrB::aph-deficient ciprofloxacin-resistant Salmonella enterica serovar enteritidis isolate 5408-cip harboring gyrA D87Y, gyrB E466D, parE V461G mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID1287977 | Antibacterial activity against Escherichia coli after 18 hrs by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 26, Issue:7 | Facile synthesis of 1,3-thiazolidin-4-ones as antitubercular agents. |
| AID1596680 | Antibacterial activity against Salmonella typhimurium ATCC 13311 after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID558316 | Antibacterial activity against Campylobacter coli assessed as resistant isolates by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID1767668 | Antibacterial activity against Streptococcus sobrinus ATCC 27351 assessed as inhibition of bacterial growth incubated for 24 hrs by microdilution assay | 2021 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 47 | Antimicrobial, modulatory, and antibiofilm activity of tt-farnesol on bacterial and fungal strains of importance to human health. |
| AID562929 | Antimicrobial activity against Clostridium difficile CD196 M1 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID557994 | Antimicrobial activity in Clostridium sordellii by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID555258 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 90 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID662081 | Antibacterial activity against Klebsiella pneumoniae after 20 hrs by liquid growth inhibition assay | 2012 | Journal of medicinal chemistry, Mar-08, Volume: 55, Issue:5 | From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity. |
| AID1471045 | Antibacterial activity against Escherichia coli NCIM 2576 measured after 8 hrs | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID590284 | Antibacterial activity against Micrococcus luteus IFC 12708 after 24 hrs by by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase. |
| AID1143591 | Antibacterial activity against Staphylococcus aureus assessed as diameter of growth inhibition zone after 24 hrs by two fold serial dilution method | 2014 | European journal of medicinal chemistry, Jun-23, Volume: 81 | Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-arylethanones: antibacterial, DNA photocleavage, and anticancer activities. |
| AID1491341 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 24 hrs by two-fold serial dilution method | 2017 | European journal of medicinal chemistry, Sep-08, Volume: 137 | Synthesis, antimicrobial, antiquorum-sensing and antitumor activities of new benzimidazole analogs. |
| AID1139544 | Antibacterial activity against Escherichia coli DH5alpha expressing beta-lactamase NDM-1 by CLSI broth microdilution method | 2014 | Journal of medicinal chemistry, May-08, Volume: 57, Issue:9 | Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. |
| AID1892312 | Antibacterial activity against Staphylococcus aureus ATCC 25923 incubated for 16 to 24 hrs in presence of rifampin by broth microdilution based spectrophotometric analysis | 2022 | Journal of natural products, 06-24, Volume: 85, Issue:6 | Glenthmycins A-M: Macrocyclic Spirotetronate Polyketide Antibacterials from the Australian Pasture Plant-Derived |
| AID1594837 | Antibacterial activity against Micrococcus flavus ATCC 10240 by microdilution method | 2019 | Journal of natural products, 06-28, Volume: 82, Issue:6 | Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. |
| AID324178 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid PhoU at 1.5 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID655626 | Antibacterial activity against Pseudomonas aeruginosa ATCC 15499 at 40 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID648404 | Antibacterial activity against Staphylococcus aureus ATTC 25923 after 16 to 18 hrs by serial dilution method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Facile synthesis, characterization and pharmacological activities of 3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 5,6-dihydro-3,6-disubstituted-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles. |
| AID426133 | Antibacterial activity against Bacillus subtilis ATCC 6633 at 100 ug/ml after 24 hrs by agar well diffusion method | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis and antimicrobial studies of novel methylene bridged benzisoxazolyl imidazo[2,1-b][1,3,4]thiadiazole derivatives. |
| AID429062 | Antimicrobial activity against Proteus mirabilis JIE273 expressing 16S rRNA methyltransferase RmtC | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | RmtC 16S rRNA methyltransferase in Australia. |
| AID456089 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID633853 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID372555 | Antibacterial activity against genetically beta-lactamase-negative ampicillin-resistant Haemophilus influenzae type b with an amino acid substitution in highly mutated locus Ser-385 of ftsI gene assessed as susceptibility rate by broth microdilution metho | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID1471210 | Antibacterial activity against Pseudomonas aeruginosa ATCC BAA-427 by spectrophotometric method | 2017 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 27, Issue:13 | Diversity-oriented sustainable synthesis of antimicrobial spiropyrrolidine/thiapyrrolizidine oxindole derivatives: New ligands for a metallo-β-lactamase from Klebsiella pneumonia. |
| AID1176774 | Antimicrobial activity against Escherichia coli ATCC 35218 after 24 hrs by broth microdilution method | 2015 | Journal of natural products, Jan-23, Volume: 78, Issue:1 | Structure and antimicrobial activity of phloroglucinol derivatives from Achyrocline satureioides. |
| AID1323304 | Antibacterial activity against Proteus hauseri NBRC 3851 after 24 hrs by serial two fold dilution method | 2016 | Journal of natural products, 07-22, Volume: 79, Issue:7 | Actinomadurol, an Antibacterial Norditerpenoid from a Rare Actinomycete, Actinomadura sp. KC 191. |
| AID1527478 | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as reduction in microbial growth after 24 to 48 hrs by microdilution susceptibility test | 2020 | European journal of medicinal chemistry, Jan-01, Volume: 185 | Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents. |
| AID442409 | Antimicrobial activity against Micrococcus flavus at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID654570 | Antibacterial activity against Staphylococcus epidermidis after 18 hrs by broth microdilution method | 2012 | Journal of natural products, Feb-24, Volume: 75, Issue:2 | Asperolides A-C, tetranorlabdane diterpenoids from the marine alga-derived endophytic fungus Aspergillus wentii EN-48. |
| AID1436573 | Antibacterial activity against Bacillus subtilis MTCC 441 by broth microdilution assay method | 2017 | Bioorganic & medicinal chemistry letters, 02-01, Volume: 27, Issue:3 | Synthesis, identification and in vitro biological evaluation of some novel quinoline incorporated 1,3-thiazinan-4-one derivatives. |
| AID382700 | Antimicrobial activity against Enterobacter aerogenes at 572.4 uM by disc-diffusion method | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives. |
| AID529742 | Antibacterial activity against Beta-lactamase positive Haemophilus influenzae harboring fst1 mutant gene assessed as resistant isolates after 20 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID368420 | Antimicrobial activity against Escherichia coli KAM32 pHPA containing mutated GyrA gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID534383 | Antibacterial activity against Escherichia coli K-12 W1895 transconjugant harboring pCF243 by microdilution method in presence of Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate. |
| AID1668058 | Inhibition of DHPS in Streptococcus pneumoniae assessed as antibacterial activity by measuring inhibition of bacterial growth incubated for 24 hrs by microbroth dilution method | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9 | New acrylamide-sulfisoxazole conjugates as dihydropteroate synthase inhibitors. |
| AID632561 | Antibacterial activity against Bacillus pumilus at 200 ug/mL after 24 hrs by agar cup diffusion method | 2011 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 21, Issue:24 | A new antifungal briarane diterpenoid from the gorgonian Junceella juncea Pallas. |
| AID1847368 | Synergistic antibacterial activity against Escherichia coli BL21 (DE3) expressing NDM-1 incubated for 12 hrs in the presence of cefuroxime sodium by two-fold checkerboard microdilution method | 2021 | European journal of medicinal chemistry, Nov-05, Volume: 223 | Recent research and development of NDM-1 inhibitors. |
| AID1776893 | Antibacterial activity against Bacillis subtilis BS-GA28 at 5 ug/ml | 2021 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 44 | Design, synthesis and antimicrobial activity of novel 2-aminothiophene containing cyclic and heterocyclic moieties. |
| AID345808 | Antimicrobial activity against Bacillus subtilis ATCC 6051 | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24 | Synthesis and antimicrobial activity of 2-alkenylchroman-4-ones, 2-alkenylthiochroman-4-ones and 2-alkenylquinol-4-ones. |
| AID372565 | Antibacterial activity against beta-lactamase-negative ampicillin-resistant Haemophilus influenzae by Etest | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID549331 | Antimicrobial activity against Escherichia coli isolate 32 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID1374418 | Antibacterial activity against Bacillus subtilis ATCC 6633 | 2018 | Bioorganic & medicinal chemistry letters, 03-01, Volume: 28, Issue:5 | Synthesis, antimicrobial activity and acid dissociation constants of methyl 5,5-diphenyl-1-(thiazol-2-yl)pyrrolidine-2-carboxylate derivatives. |
| AID655695 | Antibacterial activity against Salmonella typhimurium ATCC 23564 at 40 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID529607 | Ratio of Kcat to Km for Escherichia coli Beta-Lactamase TEM-12 | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID555217 | Antibacterial activity against Escherichia coli DH5alpha carrying ampC gene of Acinetobacter genomosp. 3 isolate 56 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID568334 | Antimicrobial activity against wild type Klebsiella pneumoniae by broth dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 21, Issue:4 | Design and synthesis of potent Gram-negative specific LpxC inhibitors. |
| AID535647 | Antimicrobial activity against Group B Streptococcus serotype V 2603 V/R harboring E63K mutation in PBP 2A and L41S mutation in PBP 1B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID548028 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237K mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID548014 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237S mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID389384 | Antibacterial activity against Staphylococcus aureus ATCC 6538 | 2008 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 18, Issue:20 | Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp. |
| AID360065 | Inhibition of Enterococcus faecium M512 LDtfm transpeptidase activity assessed as tri-aspartate-tri-aspartate-tetra multimer containing L-Lys3 to D-Asp-L-Lys3 cross links at 8 ug/ml | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID537667 | Antibacterial activity against Bacillus cereus 702 after 18 hrs by agar-well diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Cyclization of some carbothioamide derivatives containing antipyrine and triazole moieties and investigation of their antimicrobial activities. |
| AID295119 | Antibacterial activity against Micrococcus luteus La 2971 at 10 ug by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID543818 | Bactericidal activity against Escherichia coli ATCC 25922 assessed as eradication of pre-formed biofilm at 50 times MIC after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID546618 | Antimicrobial activity against Pseudomonas aeruginosa isolate 243-31C expressing beta-lactamase VIM-18 isolated from sputum of patient by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Carbapenem resistance among Pseudomonas aeruginosa strains from India: evidence for nationwide endemicity of multiple metallo-beta-lactamase clones (VIM-2, -5, -6, and -11 and the newly characterized VIM-18). |
| AID287374 | Antibacterial activity against Bacillus cereus after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID1286504 | Ratio of MBC for methicillin-sensitive Staphylococcus aureus ATCC 29213 to MIC90 for methicillin-sensitive Staphylococcus aureus ATCC 29213 | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID1411632 | Antibacterial activity against Salmonella typhimurium ATCC 13311 after 24 hrs by microdilution method | |||
| AID399620 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 at 0.1 mg/disk by disk diffusion assay | |||
| AID529620 | Antibacterial activity against Beta-lactamase positive Haemophilus influenzae assessed as resistant isolates after 20 to 24 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID543433 | Ratio of Kcat to km for Shigella sonnei UIH-1 CTX-M-64 | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime. |
| AID1657464 | Antibacterial activity against methicillin-resistant Staphylococcus aureus shhsA1 by CLSI based susceptibility test method | 2020 | Journal of natural products, 04-24, Volume: 83, Issue:4 | Proximicins F and G and Diproximicin A: Aminofurans from the Marine-Derived |
| AID562231 | Antimicrobial activity against Desulfovibrio piger in presence of Sulbactam by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID585674 | Antimicrobial activity against ampGh1 deficient Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID542768 | Antimicrobial activity against Escherichia coli J53 by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID426141 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 after 24 hrs by agar well diffusion method | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis and antimicrobial studies of novel methylene bridged benzisoxazolyl imidazo[2,1-b][1,3,4]thiadiazole derivatives. |
| AID569260 | Antimicrobial activity against Staphylococcus aureus | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives. |
| AID1769951 | Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC 43300 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID426129 | Antimicrobial activity against Bacillus cereus 702 Roma at 10 ug after 18 hrs by agar-well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities. |
| AID565057 | Antibacterial activity against wild-type Escherichia coli AG100 harboring Tn5 insertion in ycgE gene at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID278536 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium bifidum BB12 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID536236 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 441 after 24 hrs by serial dilution method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Design, synthesis and in vitro evaluation of antitubercular and antimicrobial activity of some novel pyranopyrimidines. |
| AID324985 | Antibacterial activity against Haemophilus influenzae MSC01432 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID745304 | Antibacterial activity against Salmonella typhi MTCC 98 assessed as growth inhibition after overnight incubation by NCCLS broth microdilution method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Synthesis and identification of β-aryloxyquinoline based diversely fluorine substituted N-aryl quinolone derivatives as a new class of antimicrobial, antituberculosis and antioxidant agents. |
| AID326270 | Activity of Escherichia coli beta-lactamase SCO1 relative to penicillin G | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | SCO-1, a novel plasmid-mediated class A beta-lactamase with carbenicillinase characteristics from Escherichia coli. |
| AID562809 | Antimicrobial activity against Escherichia coli J53 | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID436776 | Antibacterial activity against Staphylococcus aureus NCTC 7447 at 25 ug/mL after 24 hrs by agar diffusion assay | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10 | Synthesis, characterization and in vitro antimicrobial activity of novel 2-thioxo-4-thiazolidinones and 4,4'-bis(2-thioxo-4-thiazolidinone-3-yl)diphenylsulfones. |
| AID1651555 | Antibacterial activity against Bacillus subtilis ATCC 6633 assessed as reduction in microbial growth after incubated for 48 hrs by resazurin dye based assay | 2020 | Journal of natural products, 04-24, Volume: 83, Issue:4 | Talauxins: Hybrid Phenalenone Dimers from |
| AID509631 | Antimicrobial activity against Staphylococcus aureus RN4220 transformant carrying plasmid pKKS25 and expressing erm(T), dfrK and tet(L) genes by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID671472 | Antibacterial activity against methicillin-resistant Staphylococcus aureus expressing SSCmec subtype VT after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Aug-01, Volume: 20, Issue:15 | Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. |
| AID324362 | Ratio of kcat to Km for Acinetobacter johnsonii SCO1 | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina. |
| AID531611 | Antimicrobial activity against Escherichia coli JM109 harboring pE1 plasmid expressing beta-lactamase SHV-11 by agar dilution method in presence of Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae. |
| AID324229 | Antibacterial activity against Escherichia coli K12 containing PhoU mutant assessed as cell count in stationary phase at 100 ug/ml after 5 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID520780 | Antibacterial activity against Escherichia coli EC600 transconjugant harboring beta-lactamase KPC-2 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. |
| AID520777 | Antibacterial activity against beta-lactamase KPC-2 producing Klebsiella pneumoniae isolate K10 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. |
| AID360055 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as lactoyl penta-peptide level | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID555681 | Antimicrobial activity against Escherichia coli DH10B by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg. |
| AID382727 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by microdilution assay | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives. |
| AID521968 | Antibacterial activity against Campylobacter sp. assessed as resistance breakpoint by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3 | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. |
| AID565428 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 assessed as growth inhibition at 0.16 ug/ml | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID495750 | Antimicrobial activity against Escherichia coli J5 by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID1290441 | Antibacterial activity against Bacillus subtilis MTCC 441 after 24 to 48 hrs by broth microdilution method | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities. |
| AID1809795 | Antibiofilm activity against Enterococcus faecalis assessed as reduction in amount of viable biofilm-embedded bacterial cells at 50 uM measured by YTO 9/PI staining followed by confocal laser scanning microscopy | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Selection and Identification of Novel Antibacterial Agents against Planktonic Growth and Biofilm Formation of |
| AID585870 | Antimicrobial activity against Pseudomonas aeruginosa isolate 15 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID568825 | Antimicrobial activity against Escherichia coli ATCC 14169 at 25 ug/ml by agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis of 4H-chromene, coumarin, 12H-chromeno[2,3-d]pyrimidine derivatives and some of their antimicrobial and cytotoxicity activities. |
| AID1617941 | Antibacterial activity against Micrococcus luteus ATCC 15307 after 16 to 48 hrs | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12 | Structure Determination, Functional Characterization, and Biosynthetic Implications of Nybomycin Metabolites from a Mining Reclamation Site-Associated |
| AID1185704 | Antimicrobial activity against Bacillus cereus 709 Roma after 24 hrs by agar dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | New thiophene-1,2,4-triazole-5(3)-ones: highly bioactive thiosemicarbazides, structures of Schiff bases and triazole-thiols. |
| AID255534 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 0.5 uM/ml in dimethylformamide, + = resistant | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID151697 | In vitro antibacterial activity against ATCC 27853 strain of Pseudomonas aeruginosa | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID547169 | Antibacterial activity against Aeromonas veronii assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID278555 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium longum P/N 601377 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID425653 | Renal clearance in human | 2009 | Journal of medicinal chemistry, Aug-13, Volume: 52, Issue:15 | Physicochemical determinants of human renal clearance. |
| AID555661 | Antimicrobial activity against Salmonella enterica serotype Westhampton isolate 04CEB8273SAL expressing CTX-M-53 gene by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg. |
| AID666965 | Antifungal activity against Candida albicans MTCC 227 by broth microdilution method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | New N-arylamino biquinoline derivatives: synthesis, antimicrobial, antituberculosis, and antimalarial evaluation. |
| AID1769958 | Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC48073 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID555260 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 90 by Etest method in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID555461 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 65 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1491077 | Antibacterial activity against Staphylococcus aureus ATCC 6538p after 24 hrs by serial two fold dilution method | 2017 | Journal of natural products, 05-26, Volume: 80, Issue:5 | Manzamine Alkaloids from an Acanthostrongylophora sp. Sponge. |
| AID74719 | Inhibition of gram positive (resistant) bacteria growth. | 1989 | Journal of medicinal chemistry, Jun, Volume: 32, Issue:6 | Synthesis and antimicrobial properties of substituted beta-aminoxypropionyl penicillins and cephalosporins. |
| AID585194 | Antimicrobial activity against Escherichia coli DH5[alpha] transformed with pAC-ges1 plasmid encoding Beta-lactamase GES-7 K104, G170 mutant by Etest method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases. |
| AID1246294 | Resistance index, ratio of MIC for methicillin-resistant Staphylococcus aureus HEMSA to MIC for Staphylococcus aureus ATCC 25923 | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | Imidazolidine-4-one derivatives in the search for novel chemosensitizers of Staphylococcus aureus MRSA: synthesis, biological evaluation and molecular modeling studies. |
| AID425617 | Cmax in healthy human at 500 mg administered orally | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID333992 | Antibacterial activity against Shigella flexneri at 100 ug/100 uL after 24 hrs by tube broth dilution method | 1997 | Journal of natural products, Oct, Volume: 60, Issue:10 | New steroidal alkaloids from Buxus longifolia. |
| AID585628 | Antimicrobial activity against tetracycline resistant Escherichia coli SNO301-1 harboring pEC1C carrying ampC, ampR from Enterobacter cloacae after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID374113 | Antimicrobial activity against azide-resistant Escherichia coli J53 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID528522 | Antimicrobial activity against Streptococcus pneumoniae ATCC 49619 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID519635 | Activity of Brachyspira pilosicoli beta-lactamase OXA-63 expressed in Escherichia coli BL21 (DE3) assessed as compound hydrolysis by spectrophotometry relative to oxacillin | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442. |
| AID536084 | Antimicrobial activity against Pseudomonas aeruginosa IFO 3448 at 100 ug/8 mm disk after 24 hrs by agar disk diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID285205 | Antimicrobial activity against Escherichia coli AG112 mutant with marR genotype after 250 generations in 5 ug/ml presence of tetracycline | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID436468 | Antibacterial activity against Pseudomonas aeruginosa MTCC 741 after 20 hrs by two fold dilution method | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10 | Synthesis, physicochemical properties and antimicrobial activity of some new benzimidazole derivatives. |
| AID269643 | Antibacterial activity against Escherichia coli ATCC 25922 | 2006 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 16, Issue:16 | Lactones from a brown alga endophytic fungus (No. ZZF36) from the South China Sea and their antimicrobial activities. |
| AID565686 | Antimicrobial activity against beta-lactamase-positive ampicillin-resistant Haemophilus influenzae harboring fst1 mutant gene assessed as susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Antimicrobial activities of piperacillin-tazobactam against Haemophilus influenzae isolates, including beta-lactamase-negative ampicillin-resistant and beta-lactamase-positive amoxicillin-clavulanate-resistant isolates, and mutations in their quinolone re |
| AID510171 | Antimicrobial activity against cephalosporin-resistant Enterococcus faecalis by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID471911 | Antibacterial activity against Staphylococcus aureus MTCC 1144 at 128 ug/ml after 16 hrs by disc diffusion method | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | A facile one-pot green synthesis and antibacterial activity of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes. |
| AID1233737 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus 344/2-32 assessed as microbial growth inhibition at 1 mg/ml incubated overnight at 37 degC | 2015 | Journal of natural products, Jul-24, Volume: 78, Issue:7 | HPLC-NMR and HPLC-MS Profiling and Bioassay-Guided Identification of Secondary Metabolites from the Australian Plant Haemodorum spicatum. |
| AID556566 | Antimicrobial activity against ahpC gene-deficient Escherichia coli K-12 3200 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID582910 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61S mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1158656 | Antibacterial activity against Erwinia carotovora grown in sheep blood agar media assessed as concentration required to inhibit bacterial growth due to absence of hemolysis of erythrocytes after 18 hrs by ten-fold broth dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Eremophilane-type sesquiterpenoids with diverse skeletons from Ligularia sagitta. |
| AID334241 | Antimicrobial activity against Candida albicans after 24 hrs by microdilution technique | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4 | Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline. |
| AID569261 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus 873 | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives. |
| AID1423471 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 6 to 8 hrs by bacterial proliferation assay | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID1308868 | Antimicrobial activity against Helicobacter pylori clinical isolates assessed as inhibition of visible microbial growth incubated for 6 days by agar dilution method | 2016 | Journal of medicinal chemistry, 06-09, Volume: 59, Issue:11 | Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme. |
| AID532986 | Antibacterial activity against Pseudomonas aeruginosa NCIM 5029 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID300059 | Antibacterial activity against Escherichia coli ATCC 11230 at 10 ug after 24 hrs by disc diffusion method | 2007 | Bioorganic & medicinal chemistry, Aug-01, Volume: 15, Issue:15 | Synthesis, characterization and antimicrobial activity of new aliphatic sulfonamide. |
| AID357358 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by agar dilution method | 2001 | Journal of natural products, Aug, Volume: 64, Issue:8 | Verbalactone, a new macrocyclic dimer lactone from the roots of Verbascum undulatum with antibacterial activity. |
| AID540816 | Antimicrobial activity against marA::aph-deficient ciprofloxacin-resistant Salmonella enterica serovar enteritidis isolate 104-cip harboring gyrA D87Y,S83F mutant gene by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Multiple regulatory pathways associated with high-level ciprofloxacin and multidrug resistance in Salmonella enterica serovar enteritidis: involvement of RamA and other global regulators. |
| AID1246296 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 incubated for 20 hrs in presence of sulbactam by serial dilution broth microplate method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | Imidazolidine-4-one derivatives in the search for novel chemosensitizers of Staphylococcus aureus MRSA: synthesis, biological evaluation and molecular modeling studies. |
| AID405327 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae group IIb isolates with acrR mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID318657 | Antibacterial activity against Staphylococcus saccharolyticus GAI 5520 by broth microdilution method | 2008 | Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7 | Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens. |
| AID378240 | Antimicrobial activity against Staphylococcus aureus after 48 hrs by paper disk assay | 2000 | Journal of natural products, Nov, Volume: 63, Issue:11 | Metabolites of Colletotrichum gloeosporioides, an endophytic fungus in Artemisia mongolica. |
| AID587731 | Ratio of Kcat to Km for Pseudomonas aeruginosa strain PS 297 metallo-beta-lactamase IMP18 expressed in Escherichia coli BL21(DE3) assessed as substrate hydrolysis using 100 uM nitrocefin | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States. |
| AID1201795 | Antibacterial activity against methicillin-susceptible bloodstream form of Staphylococcus aureus ATCC 25923 after 24 hrs by two fold microdilution method | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Boronic species as promising inhibitors of the Staphylococcus aureus NorA efflux pump: study of 6-substituted pyridine-3-boronic acid derivatives. |
| AID745305 | Antibacterial activity against Escherichia coli MTCC 443 assessed as growth inhibition after overnight incubation by NCCLS broth microdilution method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Synthesis and identification of β-aryloxyquinoline based diversely fluorine substituted N-aryl quinolone derivatives as a new class of antimicrobial, antituberculosis and antioxidant agents. |
| AID1617679 | Antibacterial activity against Staphylococcus aureus 745524 by CLSI based two-fold serial dilution method | |||
| AID1767666 | Antibacterial activity against Streptococcus pyogenes ATCC 19615 assessed as inhibition of bacterial growth incubated for 24 hrs by microdilution assay | 2021 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 47 | Antimicrobial, modulatory, and antibiofilm activity of tt-farnesol on bacterial and fungal strains of importance to human health. |
| AID426127 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 at 10 ug after 18 hrs by agar-well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities. |
| AID530340 | Activity of Pseudomonas aeruginosa VIM-1 beta-lactamase | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain. |
| AID547794 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237V mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID582903 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87I mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1293901 | Antibacterial activity against Bacillus subtilis after 18 hrs by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, May-01, Volume: 26, Issue:9 | Novel tetrazoloquinoline-rhodanine conjugates: Highly efficient synthesis and biological evaluation. |
| AID1399269 | Antimicrobial activity against Klebsiella pneumoniae isolate SJ 2 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID558334 | Antibacterial activity against bla gene-positive and nitrocefin reaction-positive beta-lactamase harboring Campylobacter jejuni isolate P1093 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID1486831 | Antifungal activity against Candida albicans MTCC 227 incubated for overnight by broth micro dilution method | 2017 | Bioorganic & medicinal chemistry, 08-01, Volume: 25, Issue:15 | 1,2,4-Triazole and 1,3,4-oxadiazole analogues: Synthesis, MO studies, in silico molecular docking studies, antimalarial as DHFR inhibitor and antimicrobial activities. |
| AID368424 | Ratio of MIC for Escherichia coli KAM32 pSTVqepA mutant to MIC for Escherichia coli KAM32 pSTV28 mutant | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID1194190 | Antimicrobial activity against Escherichia coli ATCC 25922 after 24 hrs by two fold serial microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 25, Issue:8 | Studies on antimicrobial effects of four ligands and their transition metal complexes with 8-mercaptoquinoline and pyridine terminal groups. |
| AID1577948 | Antimicrobial activity against Pseudomonas aeruginosa 61 under iron-sufficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID765561 | Antimicrobial activity against Yersinia pseudotuberculosis ATCC 911 after 18 to 24 hrs by double microdilution method | 2013 | European journal of medicinal chemistry, Sep, Volume: 67 | Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities. |
| AID426124 | Antimicrobial activity against Escherichia coli ATCC 2592 at 10 ug after 18 hrs by agar-well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities. |
| AID1616519 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by broth microdilution method | 2019 | Journal of natural products, 10-25, Volume: 82, Issue:10 | Highly Oxygenated Triterpenoids and Rare Tetraterpenoids from |
| AID422495 | Antimicrobial activity against Escherichia coli BL21 (DE3) harboring pAT514 by E-test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens. |
| AID547190 | Antibacterial activity against Vibrio sp. assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID573380 | Antibacterial activity against beta lactamase-negative Haemophilus influenzae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID520707 | Antibacterial activity against Acinetobacter baumannii phenotype 2 by disk diffusion method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID289240 | Antimicrobial activity against Streptococcus faecalis | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18 | Utility of 6-amino-2-thiouracil as a precursor for the synthesis of bioactive pyrimidine derivatives. |
| AID420213 | Antimicrobial activity against Bacillus subtilis UFPEDA 16 after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID528699 | Antibacterial activity against vancomycin resistant Enterococcus faecalis VanB clinical isolate assessed as susceptibility level by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | In vitro activity of telavancin against resistant gram-positive bacteria. |
| AID1286492 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 29213 after 20 to 24 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID546922 | Antibacterial activity against Escherichia coli assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID587975 | Ratio of Kcat to Km for Escherichia coli beta-lactamase Toho-1 F160T mutant assessed as compound hydrolysis by spectrophotometry | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID1535448 | Anti-biofilm activity against Pseudoalteromonas lipolytica TC8 assessed as inhibition of bacterial adhesion incubated for 15 hrs at 20 degC by Syto 61 dye based fluorimetric assay | 2019 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 29, Issue:4 | Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds? |
| AID442408 | Antimicrobial activity against Bacillus cereus at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID531612 | Antimicrobial activity against Escherichia coli JM109 harboring pSC1 plasmid expressing beta-lactamase SHV-56 by agar dilution method in presence of Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae. |
| AID476929 | Human intestinal absorption in po dosed human | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Neural computational prediction of oral drug absorption based on CODES 2D descriptors. |
| AID535671 | Antimicrobial activity against beta-lactamase negative, ampicillin-resistant Haemophilus influenzae expressing fst1 mutant gene assessed as resistant isolates by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Genotypic versus phenotypic characterization, with respect to beta-lactam susceptibility, of Haemophilus influenzae isolates exhibiting decreased susceptibility to beta-lactam resistance markers. |
| AID777335 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition after 24 hrs by microbroth dilution method | 2013 | ACS medicinal chemistry letters, Oct-10, Volume: 4, Issue:10 | Identification of 1-[4-Benzyloxyphenyl)-but-3-enyl]-1H-azoles as New Class of Antitubercular and Antimicrobial Agents. |
| AID530203 | Antimicrobial activity against Mycobacterium bovis BCG ML1041 carrying transposon IS1096::Km inserted at +1707bp of ppe24 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1347486 | Antibacterial activity against Streptococcus pyogenes assessed as zone of inhibition after 24 to 48 hrs by well diffusion method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Newly designed organotin(IV) carboxylates with peptide linkage: Synthesis, structural elucidation, physicochemical characterizations and pharmacological investigations. |
| AID670269 | Antibacterial activity against Staphylococcus aureus ATCC 6538p after 24 hrs | 2012 | Bioorganic & medicinal chemistry, Jul-01, Volume: 20, Issue:13 | Beta-carboline alkaloids derived from the ascidian Synoicum sp. |
| AID1908122 | Antibacterial activity against Enterococcus faecium ATCC 49624 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID304977 | Antifungal activity against Candida parapsilosis ATCC 22019 by broth micro-dilution technique | 2007 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1 | New antifungal flavonoid glycoside from Vitex negundo. |
| AID582911 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61P mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID584472 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN02 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID555480 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 14 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID536634 | Antimicrobial activity against Escherichia coli NCTC 10416 by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis of new pyrrolo[2,3-d]pyrimidine derivatives as antibacterial and antifungal agents. |
| AID1399272 | Antimicrobial activity against Klebsiella pneumoniae isolate SJ 5 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID727657 | Antimicrobial activity against Escherichia coli DH10B expressing Beta-lactamase SHV-1 K234X protein mutant by CLSI agar dilution method | 2013 | Journal of medicinal chemistry, Feb-14, Volume: 56, Issue:3 | Design and exploration of novel boronic acid inhibitors reveals important interactions with a clavulanic acid-resistant sulfhydryl-variable (SHV) β-lactamase. |
| AID555234 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 20 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID574174 | Antibacterial activity against Escherichia coli OCL62 grown as biofilms harboring plasmid pBR322 carrying blaTEM-1 and tetA(C) genes after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID542770 | Antimicrobial activity against Escherichia coli J53 transformed with pHND2 carrying qnrB6 and CTX-M-9G genes by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID662991 | Antibacterial activity against Vibrio cholerae MTCC 3906 by macrobroth dilution assay | 2012 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 22, Issue:12 | An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidines. |
| AID1322103 | Antimicrobial activity against Proteus vulgaris ATCC 13315 after 24 hrs by broth microdilution assay | 2016 | Bioorganic & medicinal chemistry, 11-01, Volume: 24, Issue:21 | Synthesis, characterization, and evaluation of (E)-methyl 2-((2-oxonaphthalen-1(2H)-ylidene)methylamino)acetate as a biological agent and an anion sensor. |
| AID750276 | Antibacterial activity against Streptococcus pyogenes MTCC 442 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents. |
| AID1304324 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 assessed as growth inhibition after 18 to 20 hrs by microdilution assay | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | Caged xanthones: Potent inhibitors of global predominant MRSA USA300. |
| AID360858 | Antibacterial activity against Klebsiella pneumoniae subsp. pneumoniae ATCC 13833 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID1399253 | Antimicrobial activity against Bacillus anthracis Sterne 34F2 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID567578 | Antimicrobial activity against Acinetobacter baumannii assessed as resistant isolate by broth dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | In vitro antimicrobial activity and mutant prevention concentration of colistin against Acinetobacter baumannii. |
| AID562382 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecium clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1233738 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 assessed as microbial growth inhibition at 1 mg/ml incubated overnight at 37 degC | 2015 | Journal of natural products, Jul-24, Volume: 78, Issue:7 | HPLC-NMR and HPLC-MS Profiling and Bioassay-Guided Identification of Secondary Metabolites from the Australian Plant Haemodorum spicatum. |
| AID1695863 | Antibacterial activity against Pseudomonas fluorescens NCIM 2173 incubated for 24 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID1168640 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 at 10 ug after 18 hrs by agar well diffusion assay | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Phosphorus-nitrogen compounds. Part 29. Syntheses, crystal structures, spectroscopic and stereogenic properties, electrochemical investigations, antituberculosis, antimicrobial and cytotoxic activities and DNA interactions of ansa-spiro-ansa cyclotetrapho |
| AID562218 | Antimicrobial activity against Desulfovibrio fairfieldensis in presence of Sulbactam by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Susceptibilities of 23 Desulfovibrio isolates from humans. |
| AID562387 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecalis clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1585537 | Antibacterial activity against Pseudomonas aeruginosa assessed as zone of inhibition at 50 ug/ml after 3 days by filter paper disc method | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Benzofuran derivatives and their anti-tubercular, anti-bacterial activities. |
| AID584301 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus sciuri subsp. carnaticus ATCC 700058T by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID1908120 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID472403 | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 24 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry, Apr-15, Volume: 18, Issue:8 | Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives. |
| AID546946 | Antibacterial activity against Salmonella enterica serovar Heidelberg assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID548945 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 after18 to 20 hrs by broth dilution method | 2010 | European journal of medicinal chemistry, Dec, Volume: 45, Issue:12 | Synthesis and antimicrobial evaluation of some fused heterocyclic [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives. |
| AID558333 | Antibacterial activity against bla gene-positive and nitrocefin reaction-positive beta-lactamase harboring Campylobacter jejuni isolate P790 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID352583 | Antimicrobial activity against Bacillus cereus 702 Roma at 10 ug after 18 hrs by agar-well diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Synthesis of some new 1,2,4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities. |
| AID568329 | Antimicrobial activity against wild type Escherichia coli by broth dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 21, Issue:4 | Design and synthesis of potent Gram-negative specific LpxC inhibitors. |
| AID1433838 | Antibacterial activity against Salmonella typhi MTCC 98 after 24 to 48 hrs by broth microdilution method | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs. |
| AID1594847 | Antibiofilm activity against Pseudomonas aeruginosa PAO1 assessed as inhibition of biofilm formation at 0.125 times MIC incubated for 24 hrs by crystal violet staining based ELISA method | 2019 | Journal of natural products, 06-28, Volume: 82, Issue:6 | Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. |
| AID1264892 | Antimicrobial activity against Mycobacterium smegmatis ATCC 14468 for 17 to 48 hrs by MTT assay | 2015 | Journal of natural products, Nov-25, Volume: 78, Issue:11 | Identification of Elaiophylin Skeletal Variants from the Indonesian Streptomyces sp. ICBB 9297. |
| AID285688 | Antimicrobial susceptibility of carbapenem-resistant Pseudomonas aeruginosa PA2404 isolate expressing carbapenemase KPC2 | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First identification of Pseudomonas aeruginosa isolates producing a KPC-type carbapenem-hydrolyzing beta-lactamase. |
| AID1551862 | Antibacterial activity against Enterococcus faecalis | 2019 | European journal of medicinal chemistry, Jul-15, Volume: 174 | 1,2,4-Triazole-quinoline/quinolone hybrids as potential anti-bacterial agents. |
| AID532985 | Antibacterial activity against Escherichia coli MG1655 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID644170 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID567762 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID584770 | Antimicrobial activity against Acinetobacter lwoffii isolate I expressing beta-lactamase OXA-58 isolated from tracheal secretion of patient in presence of Sulbactam by vitek 2 system | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | In vivo selection of a missense mutation in adeR and conversion of the novel blaOXA-164 gene into blaOXA-58 in carbapenem-resistant Acinetobacter baumannii isolates from a hospitalized patient. |
| AID547799 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237F mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID564819 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus hominis assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID530510 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype III isolate 6138-03 expressing pbp2x Q557E mutant and multilocus sequence type ST19 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID436465 | Antibacterial activity against Bacillus subtilis MTCC 121 after 20 hrs by two fold dilution method | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10 | Synthesis, physicochemical properties and antimicrobial activity of some new benzimidazole derivatives. |
| AID657438 | Antibacterial activity against vancomycin-susceptible Enterococcus faecium after 16 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9 | Preparation, antibacterial evaluation and preliminary structure-activity relationship (SAR) study of benzothiazol- and benzoxazol-2-amine derivatives. |
| AID1402052 | Antibacterial activity against Escherichia coli ATCC 8739 after 18 to 20 hrs by spectrophotometry based microdilution method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid. |
| AID558533 | Antibacterial activity against bla gene-positive and nitrocefin reaction-negative beta-lactamase harboring Campylobacter jejuni isolate P1698 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID426131 | Antimicrobial activity against Candida albicans ATCC 60193 at 5 ug after 18 hrs by agar-well diffusion assay | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities. |
| AID1608429 | Antibacterial activity against Streptococcus pneumoniae | 2019 | European journal of medicinal chemistry, Oct-15, Volume: 180 | Role of sulphur-heterocycles in medicinal chemistry: An update. |
| AID1617678 | Antibacterial activity against Staphylococcus aureus ATCC 292132 by CLSI based two-fold serial dilution method | |||
| AID535697 | Antimicrobial activity against Azide-resistant Escherichia coli J53 by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Detection of the pandemic O25-ST131 human virulent Escherichia coli CTX-M-15-producing clone harboring the qnrB2 and aac(6')-Ib-cr genes in a dog. |
| AID584470 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus vitulinus SVMP06 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID1235344 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus 344/2-32 assessed as zone of inhibition at 2862 uM incubated overnight at 37 degC | 2015 | Journal of natural products, Jul-24, Volume: 78, Issue:7 | Phytochemical Investigation of the Constituents Derived from the Australian Plant Macropidia fuliginosa. |
| AID633852 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID1412929 | Bactericidal activity against Bacillus cereus clinical isolate by microdilution method | 2018 | MedChemComm, May-01, Volume: 9, Issue:5 | Design, synthesis and antimicrobial activity of usnic acid derivatives. |
| AID558335 | Antibacterial activity against Campylobacter jejuni isolate P1093 harboring blaOXA-61::cat gene by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID1647685 | Antibacterial activity against Enterococcus hirae ATCC 8043 assessed as reduction in microbial growth after 24 hrs by agar well diffusion assay | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Isolation, Identification, and Decomposition of Antibacterial Dialkylresorcinols from a Chinese |
| AID420219 | Antimicrobial activity against multidrug-resistant Staphylococcus aureus H.C. 21141 isolate after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID294832 | Antibacterial activity against Streptococcus pyogenes after 24 hrs by microdilution broth method | 2007 | Bioorganic & medicinal chemistry, Apr-15, Volume: 15, Issue:8 | Identification of antitumour activity of novel derivatives of 8-aryl-2,6,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazine-3,4-dione and 8-aryl-4-imino-2,3,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazin-3(6H)-one. |
| AID544272 | Antimicrobial activity against Enterococcus faecalis NKH2 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID529894 | Antimicrobial activity against Leptospira interrogans serovar Grippotyphosa isolate 2 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID295107 | Antibacterial activity against Proteus vulgaris ATCC 8427 at 10 ug after 24 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. |
| AID1436572 | Antibacterial activity against Streptococcus pneumoniae MTCC 1936 by broth microdilution assay method | 2017 | Bioorganic & medicinal chemistry letters, 02-01, Volume: 27, Issue:3 | Synthesis, identification and in vitro biological evaluation of some novel quinoline incorporated 1,3-thiazinan-4-one derivatives. |
| AID586086 | Antimicrobial activity against verocytotoxin-producing Escherichia coli isolate O157 obtained from animals and food assessed as percentage of resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID1818976 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 assessed as bacterial clearance incubated for 6 to 24 hrs by microbroth dilution method | 2022 | Journal of medicinal chemistry, 01-13, Volume: 65, Issue:1 | Discovery of |
| AID1592958 | Antibacterial activity against multi-drug resistant Escherichia coli NMI 3898/15 assessed as reduction in microbial growth incubated for 20 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. |
| AID546938 | Antibacterial activity against Salmonella enterica serovar Choleraesuis assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID555474 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 195 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1143589 | Antibacterial activity against Escherichia coli assessed as diameter of growth inhibition zone after 24 hrs by two fold serial dilution method | 2014 | European journal of medicinal chemistry, Jun-23, Volume: 81 | Synthesis and biological evaluation of some 2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-arylethanones: antibacterial, DNA photocleavage, and anticancer activities. |
| AID529904 | Antimicrobial activity against Leptospira interrogans serovar Canicola isolate 11 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID1769805 | Antimicrobial activity against Staphylococcus aureus Sau 6917 assessed as inhibition of bacterial growth incubated for 16 to 18 hrs by broth micro dilution technique | |||
| AID514127 | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 assessed as growth inhibition at 1 mg/ml after 16 to 20 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays. |
| AID288605 | Antibacterial activity against Bacillus subtilis ATCC 14289 | 2007 | Journal of medicinal chemistry, May-31, Volume: 50, Issue:11 | Antibacterial nicotinamide adenine dinucleotide synthetase inhibitors: amide- and ether-linked tethered dimers with alpha-amino acid end groups. |
| AID373987 | Antimicrobial activity against azide-resistant aac(6')-Ib-cr deficient Escherichia coli J53 qnrA1 bearing pHS4 transconjugant from Enterobacter cloacae 91 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID497692 | Antimicrobial activity against Klebsiella pneumoniae isolated from bacteremia patient assessed as percentage of resistant isolates by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Nonclonal emergence of colistin-resistant Klebsiella pneumoniae isolates from blood samples in South Korea. |
| AID562354 | Antimicrobial activity against erythromycin-, streptomycin-resistant Enterococcus faecium A expressing hylEfm gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Cotransfer of antibiotic resistance genes and a hylEfm-containing virulence plasmid in Enterococcus faecium. |
| AID536078 | Antimicrobial activity against Bacillus subtilis IFO 3007 at 100 ug/8 mm disk after 24 hrs by agar disk diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis, antimicrobial and anti-inflammatory activities of novel 5-(1-adamantyl)-1,3,4-thiadiazole derivatives. |
| AID1056537 | Antibacterial activity against Micrococcus luteus by broth microdilution method | 2013 | Journal of natural products, Dec-27, Volume: 76, Issue:12 | Cytotoxic and antibacterial marfuraquinocins from the deep South China Sea-derived Streptomyces niveus SCSIO 3406. |
| AID1379746 | Antimicrobial activity against Staphylococcus aureus incubated for 24 hrs by disc diffusion assay | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of cyclopenta(hepta)[b]thiophene and fused cyclohepta[b]thiophene analogs. |
| AID278244 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-4 with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID519660 | Antimicrobial activity against Escherichia coli EPI300 harboring GM2995 pCC1 carrying beta-lactamase CTX-M-3 gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID585860 | Antimicrobial activity against Pseudomonas aeruginosa isolate 10 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID666958 | Antibacterial activity against Bacillus subtilis MTCC 441 by broth microdilution method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | New N-arylamino biquinoline derivatives: synthesis, antimicrobial, antituberculosis, and antimalarial evaluation. |
| AID585419 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W281-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID328053 | Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage at 200 nM | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Jul-24, Volume: 104, Issue:30 | Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase. |
| AID775560 | Antimicrobial activity against Bacillus cereus ATCC 14579 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21 | New derivatives of salicylamides: Preparation and antimicrobial activity against various bacterial species. |
| AID324986 | Antibacterial activity against Haemophilus influenzae MSC06647 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID577206 | Antimicrobial activity against Escherichia coli O157:H7 PT-32 in stationary phase encoding Stx-1 and Stx-2 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID585445 | Antimicrobial activity against ampG deficient Pseudomonas aeruginosa PAO1 harboring pZY0908 conferring resistance to gentamycin after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID208146 | In vivo efficacy was determined against Streptococcus pneumoniae C 0096 | 1995 | Journal of medicinal chemistry, Jun-09, Volume: 38, Issue:12 | Synthesis and biological evaluation of a series of new parenteral optically active 3-[[(N-alkylpyridinium-4'-yl)thio]methyl]-2-oxaisocephems. |
| AID382692 | Antimicrobial activity against Proteus vulgaris at 572.4 uM by disc-diffusion method | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives. |
| AID555232 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 20 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID324209 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 assessed as cell count in stationary phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID549333 | Antimicrobial activity against Escherichia coli isolate 36 harboring bla CTX-M-3a gene by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures. |
| AID568339 | Antimicrobial activity against ESBL producing Enterobacter cloacae by broth dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 21, Issue:4 | Design and synthesis of potent Gram-negative specific LpxC inhibitors. |
| AID1235347 | Antimicrobial activity against Candida albicans ATCC 10231 assessed as zone of inhibition at 2862 uM incubated overnight at 37 degC | 2015 | Journal of natural products, Jul-24, Volume: 78, Issue:7 | Phytochemical Investigation of the Constituents Derived from the Australian Plant Macropidia fuliginosa. |
| AID372559 | Antibacterial activity against genetically beta-lactamase-negative ampicillin-susceptible Haemophilus influenzae type b without amino acid substitutions in ftsI gene and bla gene assessed as resistance rate by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID585440 | Antimicrobial activity against ampG, ampGh1 deficient Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1551784 | Antibacterial activity against Streptococcus pneumoniae | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID374024 | Ratio of Kcat to Km for Enterobacter cloacae IMI1 beta lactamase Escherichia coli DH5alpha by SDS-PAGE | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase. |
| AID547635 | Antimicrobial activity against Staphylococcus aureus ATCC 19433 after 24 to 48 hrs by micro dilution susceptibility test | 2010 | European journal of medicinal chemistry, Dec, Volume: 45, Issue:12 | Synthesis and biological evaluation of some thiazolylpyrazole derivatives as dual anti-inflammatory antimicrobial agents. |
| AID1821098 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as inhibition of bacterial growth incubated for 24 hr by CLSI based broth microdilution method | |||
| AID324168 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 at 25 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID373671 | Antibacterial activity against Klebsiella pneumoniae NCIMB 9111 at 10 ug/disk after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Apr, Volume: 44, Issue:4 | Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine. |
| AID542759 | Antimicrobial activity against Escherichia coli Du19 expressing qnrB6 and CTX-M-9G genes by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID590291 | Antifungal activity against Trichophyton mentagrophytes IFO 40996 at 100 ug/ml after 2 weeks | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase. |
| AID530214 | Antimicrobial activity against Mycobacterium bovis BCG ML1006 carrying transposon IS1096::Km inserted at +720bp of bcg3787 gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID324285 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoB mutant assessed as cell count in stationary phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID521325 | Antimicrobial activity against beta lactamase-nonproducing ampicillin-resistant Haemophilus influenzae MSC06663 isolate harboring Met377Ile, Ser385Thr and Asn526Lys mutations in penicillin-binding protein 3 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Comparison of the efficacies of oral beta-lactams in selection of Haemophilus influenzae transformants with mutated ftsI genes. |
| AID1225290 | Antibacterial activity against Salmonella enterica ATCC 14028 incubated for 12 hrs at 37 degC | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Pentacyclic antibiotics from a tidal mud flat-derived actinomycete. |
| AID546943 | Antibacterial activity against Salmonella enterica serovar Virchow assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID717349 | Antimicrobial activity against Kocuria rhizophila NBRC 12708 after 24 hrs | 2012 | Journal of natural products, Dec-28, Volume: 75, Issue:12 | Brominated aromatic furanones and related esters from the ascidian Synoicum sp. |
| AID1079939 | Cirrhosis, proven histopathologically. Value is number of references indexed. [column 'CIRRH' in source] | |||
| AID1402054 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 18 to 20 hrs by spectrophotometry based microdilution method | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Synthesis and antimicrobial activity of amino acid and peptide derivatives of mycophenolic acid. |
| AID562927 | Antimicrobial activity against Clostridium difficile ATCC 43603-M1 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains. |
| AID582917 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61T mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1551782 | Antibacterial activity against Escherichia coli | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID489651 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID519661 | Antimicrobial activity against Escherichia coli EPI300 harboring GM2995 pCC1 carrying beta-lactamase CTX-M-3 Ser167 mutant gene by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID530506 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype II isolate 9051-04 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID285190 | Antimicrobial activity against Escherichia coli AG100 mutant with argE3 thi-3 rpsL xyl mtl supE44 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID607161 | Antimicrobial activity against Bacillus subtilis after 24 hrs by disc diffusion method | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14 | Exploration of antimicrobial and antioxidant potential of newly synthesized 2,3-disubstituted quinazoline-4(3H)-ones. |
| AID585859 | Antimicrobial activity against Pseudomonas aeruginosa isolate 10 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID624606 | Specific activity of expressed human recombinant UGT1A1 | 2000 | Annual review of pharmacology and toxicology, , Volume: 40 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. |
| AID1075974 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 72 hrs by broth micro-dilution method | 2014 | European journal of medicinal chemistry, Mar-21, Volume: 75 | Toward new classes of potent antibiotics: synthesis and antimicrobial activity of novel metallosaldach-imidazolium salts. |
| AID426134 | Antibacterial activity against Escherichia coli ATCC 35218 at 100 ug/ml after 24 hrs by agar well diffusion method | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis and antimicrobial studies of novel methylene bridged benzisoxazolyl imidazo[2,1-b][1,3,4]thiadiazole derivatives. |
| AID442419 | Antimicrobial activity against Escherichia coli at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID420204 | Antimicrobial activity against Micrococcus luteus UFPEDA 06 at 10 ug/disk after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID285198 | Antimicrobial activity against Escherichia coli M084 mutant AG100 lon4::IS186 genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID535636 | Antimicrobial activity against Group B streptococcus serotype VI R4 harboring Q557E mutation in PBP 2X and T567I, Y262N mutations in PBP 2B by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID1617945 | Antibacterial activity against Salmonella enterica ATCC 10708 after 16 to 48 hrs | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12 | Structure Determination, Functional Characterization, and Biosynthetic Implications of Nybomycin Metabolites from a Mining Reclamation Site-Associated |
| AID613611 | Antibacterial activity against 10'8 CFU/mL Streptococcus pneumoniae MTCC 1936 by NCCLS M100-S12(M7) broth microdilution method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis and identification of β-aryloxyquinolines and their pyrano[3,2-c]chromene derivatives as a new class of antimicrobial and antituberculosis agents. |
| AID519654 | Antimicrobial activity against Escherichia coli GM2995 harboring plasmid pCC1 carrying beta-lactamase CTX-M-3 from by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID255519 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 2.0 uM/ml in dimethylformamide, + = resistant | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID1399260 | Antimicrobial activity against Acinetobacter baumannii ATCC 19606 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID525547 | Antimicrobial activity against ampicillin resistant nontypeable Haemophilus influenzae isolate BB1050 harboring with plasmid pB1000 bearing beta-lactamase ROB-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Haemophilus influenzae clinical isolates with plasmid pB1000 bearing blaROB-1: fitness cost and interspecies dissemination. |
| AID1728305 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as diameter of inhibition zone at 10 mg/ml by disk diffusion assay | 2021 | European journal of medicinal chemistry, Jan-15, Volume: 210 | Preparation of new 1,3-dibenzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. |
| AID74700 | Inhibition of gram negative bacteria growth. | 1989 | Journal of medicinal chemistry, Jun, Volume: 32, Issue:6 | Synthesis and antimicrobial properties of substituted beta-aminoxypropionyl penicillins and cephalosporins. |
| AID318710 | Antimicrobial activity against penicillin-resistant Staphylococcus epidermidis by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID1484006 | Antimicrobial activity against Bacillus subtilis subsp. subtilis str. 168 assessed as growth inhibition zone after 18 hrs by disc diffusion method | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2 | Discovery of C-Glycosylpyranonaphthoquinones in Streptomyces sp. MBT76 by a Combined NMR-Based Metabolomics and Bioinformatics Workflow. |
| AID489649 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID530256 | Antimicrobial activity against dnaK deficient Escherichia coli K-12 BW-25113 assessed as decrease in persistence at 100 ug/ml after 3 hrs by time kill analysis | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. |
| AID123074 | The compound was tested for minimal inhibitory concentration against Micrococcus luteus | 2002 | Bioorganic & medicinal chemistry letters, Sep-02, Volume: 12, Issue:17 | The activity of p-methoxybenzylisothiocyanate against Neisseria gonorrhoeae, Haemophilus ducreyi, and other microorganisms. |
| AID405320 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae group IIc isolates with acrR baseC insertion mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID662079 | Antibacterial activity against Salmonella typhimurium after 20 hrs by liquid growth inhibition assay | 2012 | Journal of medicinal chemistry, Mar-08, Volume: 55, Issue:5 | From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity. |
| AID1853149 | Antibacterial activity against Macrolide resistant Streptococcus pneumoniae clinical isolate B0326 assessed as inhibition of bacterial growth incubated for 20 to 22 hrs by broth microdilution method | 2022 | RSC medicinal chemistry, Dec-14, Volume: 13, Issue:12 | Novel tetrahydropyrimidinyl-substituted benzimidazoles and benzothiazoles: synthesis, antibacterial activity, DNA interactions and ADME profiling. |
| AID529610 | Antibacterial activity against Beta-lactamase negative Haemophilus influenzae assessed as susceptible isolates after 20 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID304972 | Antifungal activity against Candida albicans by broth micro-dilution technique | 2007 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 17, Issue:1 | New antifungal flavonoid glycoside from Vitex negundo. |
| AID723717 | Bactericidal activity against Micrococcus flavus ATCC 10240 after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID655704 | Antibacterial activity against Salmonella typhimurium ATCC 23564 after 24 hrs by serial broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID528521 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae ATCC BAA-611 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID396028 | Antibacterial activity against drug-resistant AcrAB-TolC efflux pump deficient Enterobacter cloacae EcdeltaacrA isolate by Etest | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate. |
| AID278266 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CHS18 acrAB::Kan with GyrA S38F mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1892314 | Antibacterial activity against Enterococcus faecalis incubated for 16 to 24 hrs in presence of rifampicin by broth microdilution based spectrophotometric analysis | 2022 | Journal of natural products, 06-24, Volume: 85, Issue:6 | Glenthmycins A-M: Macrocyclic Spirotetronate Polyketide Antibacterials from the Australian Pasture Plant-Derived |
| AID405820 | Antimicrobial activity against Acinetobacter baumannii 501 isolate harboring bla IMP-1 carrying integron In86 containing aminoglycoside resistance gene aac(6')-3 | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital. |
| AID723716 | Bactericidal activity against Bacillus cereus clinical isolate after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID660265 | Antimicrobial activity against wild type Escherichia coli expressing AcrAB-TolC efflux pump | 2012 | European journal of medicinal chemistry, Jun, Volume: 52 | Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics. |
| AID1235252 | Antimicrobial activity against Escherichia coli incubated for 4 days by broth microdilution method | 2015 | Journal of natural products, Jul-24, Volume: 78, Issue:7 | Cytotoxic Homoisoflavones from the Bulbs of Bellevalia eigii. |
| AID318708 | Antimicrobial activity against penicillin-resistant Staphylococcus aureus by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID545442 | Antimicrobial activity against Klebsiella pneumoniae assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID495332 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with Ser311Pro, Ala502Thr, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID657439 | Antibacterial activity against vancomycin-resistant Enterococcus faecium after 16 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9 | Preparation, antibacterial evaluation and preliminary structure-activity relationship (SAR) study of benzothiazol- and benzoxazol-2-amine derivatives. |
| AID1156860 | Antimicrobial activity against Pseudomonas aeruginosa ATCC BAA-427 after 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of 2,3,6-trideoxy sugar triazole hybrids as potential new broad spectrum antimicrobial agents. |
| AID355421 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs by broth microdilution method | 2003 | Journal of natural products, Dec, Volume: 66, Issue:12 | New triterpene glycosides from the stems of Anomospermum grandifolium. |
| AID565062 | Antibacterial activity against wild-type Escherichia coli AG100 at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID1225328 | Antimicrobial activity against Staphylococcus aureus incubated for 24 hrs | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Alkaloidal metabolites from a marine-derived Aspergillus sp. fungus. |
| AID1466812 | Antibacterial activity against Escherichia coli ATCC 11229 assessed as diameter of inhibition zone after 24 hrs by agar well diffusion method | 2017 | Bioorganic & medicinal chemistry letters, 06-15, Volume: 27, Issue:12 | Synthesis and in vitro biological evaluation of novel coumarin derivatives containing isoxazole moieties on melanin synthesis in B16 cells and inhibition on bacteria. |
| AID334238 | Antimicrobial activity against Trichophyton interdigitale EQ 4115 after 10 days by microdilution technique | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4 | Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline. |
| AID333994 | Antibacterial activity against Salmonella typhi assessed per 100 uL of nutrient broth after 24 hrs by tube broth dilution method | 1997 | Journal of natural products, Oct, Volume: 60, Issue:10 | New steroidal alkaloids from Buxus longifolia. |
| AID603039 | Antimicrobial activity against Escherichia coli at 1 ug/mL after 48 hrs by cup plate agar diffusion method | 2011 | European journal of medicinal chemistry, Jul, Volume: 46, Issue:7 | Synthesis, antitumor and antimicrobial activities of 4-(4-chlorophenyl)-3-cyano-2-(β-O-glycosyloxy)-6-(thien-2-yl)-nicotinonitrile. |
| AID1141112 | Antimicrobial activity against Serratia marcescens ATCC 14576 at 128 uM after 24 to 48 hrs by two-fold broth microdilution method | 2014 | Bioorganic & medicinal chemistry, May-15, Volume: 22, Issue:10 | Exploring 5-nitrofuran derivatives against nosocomial pathogens: synthesis, antimicrobial activity and chemometric analysis. |
| AID1493685 | Antimicrobial activity against Bacillus subtilis RCMB 010063 assessed as diameter of zone inhibition at 1 mg/ml after 24 hrs by agar well diffusion assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Quinoline derivatives bearing pyrazole moiety: Synthesis and biological evaluation as possible antibacterial and antifungal agents. |
| AID487480 | Antibacterial activity against Klebsiella pneumoniae NCIM 2957; ATCC 11298 after 24 hrs by microtitration method | 2010 | European journal of medicinal chemistry, Jun, Volume: 45, Issue:6 | Design, synthesis, characterization, and antibacterial activity of {5-chloro-2-[(3-substitutedphenyl-1,2,4-oxadiazol-5-yl)-methoxy]-phenyl}-(phenyl)-methanones. |
| AID530502 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype IA isolate 7490-03 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID1262360 | Antibacterial activity against clinical isolate Gram-negative Pseudomonas syringae after 24 hrs by agar diffusion assay | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | PPL catalyzed four-component PASE synthesis of 5-monosubstituted barbiturates: Structure and pharmacological properties. |
| AID558006 | Antimicrobial activity in Clostridium hastiforme by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID662075 | Antibacterial activity against Enterococcus faecalis after 20 hrs by liquid growth inhibition assay | 2012 | Journal of medicinal chemistry, Mar-08, Volume: 55, Issue:5 | From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity. |
| AID1657465 | Antibacterial activity against Bacillus subtilis 1064 by CLSI based susceptibility test method | 2020 | Journal of natural products, 04-24, Volume: 83, Issue:4 | Proximicins F and G and Diproximicin A: Aminofurans from the Marine-Derived |
| AID436466 | Antibacterial activity against Streptococcus mutans MTCC 890 after 20 hrs by two fold dilution method | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10 | Synthesis, physicochemical properties and antimicrobial activity of some new benzimidazole derivatives. |
| AID514131 | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 assessed as growth inhibition at 1 mg/ml after 16 to 20 hrs in presence of 0.2 mM L-histidine | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays. |
| AID540212 | Mean residence time in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID571784 | Antibacterial activity against Salmonella enterica serovar Typhimurium 14028s by CLSI M7-A7 microdilution method | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Inhibition of intracellular growth of Salmonella enterica serovar Typhimurium in tissue culture by antisense peptide-phosphorodiamidate morpholino oligomer. |
| AID1399276 | Antimicrobial activity against Escherichia coli isolate SJ 4 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID568676 | Antimicrobial activity against Neisseria mucosa assessed as growth inhibition at 10 ug/ml by agar dilution method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and structure-activity relationship of 2-thiopyrimidine-4-one analogs as antimicrobial and anticancer agents. |
| AID514124 | Cytotoxicity against human CL1 cells expressing hTERT assessed as cell viability at 100 ug/ml after 24 hrs by trypan blue exclusion assay | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays. |
| AID1668052 | Inhibition of DHPS in Streptococcus pneumoniae assessed as antibacterial activity by measuring inhibition zone at 5 mg/mL incubated for 24 hrs by disk diffusion method | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9 | New acrylamide-sulfisoxazole conjugates as dihydropteroate synthase inhibitors. |
| AID1591742 | Antibacterial activity against Escherichia coli MTCC 443 after 24 hrs by serial dilution method | 2019 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 29, Issue:16 | Rational design, molecular docking and synthesis of novel homopiperazine linked imidazo[1,2-a]pyrimidine derivatives as potent cytotoxic and antimicrobial agents. |
| AID548743 | Antimicrobial activity against Vancomycin-susceptible Enterococcus faecium assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID600678 | Antibacterial activity against Enterococcus faecalis isolate obtained from human after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID1825299 | Antibacterial activity against Helicobacter pylori 159 assessed as bacterial growth inhibition | |||
| AID1541613 | Antibacterial activity against Micrococcus luteus assessed as bacterial growth inhibition by CLSI protocol based broth microdilution assay | 2019 | Journal of natural products, 12-27, Volume: 82, Issue:12 | Structure, Biosynthesis, and Bioactivity of Photoditritide from |
| AID395352 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 1 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID1180292 | Bactericidal activity against Bacillus subtilis NCIM-2063 after 72 hrs by two fold serial macrodilution technique | 2014 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15 | One pot three components microwave assisted and conventional synthesis of new 3-(4-chloro-2-hydroxyphenyl)-2-(substituted) thiazolidin-4-one as antimicrobial agents. |
| AID447070 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 10 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID558327 | Antibacterial activity against bla gene-positive and nitrocefin reaction-positive beta-lactamase harboring Campylobacter jejuni isolate P285 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID654567 | Antibacterial activity against methicillin-resistant Staphylococcus aureus after 18 hrs by broth microdilution method | 2012 | Journal of natural products, Feb-24, Volume: 75, Issue:2 | Asperolides A-C, tetranorlabdane diterpenoids from the marine alga-derived endophytic fungus Aspergillus wentii EN-48. |
| AID564229 | Ratio of Kcat to Km for Escherichia coli TOP10 beta-lactamase OXA-143 | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | OXA-143, a novel carbapenem-hydrolyzing class D beta-lactamase in Acinetobacter baumannii. |
| AID533400 | Antimicrobial activity against Clostridium paraputrificum assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID324300 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoB mutant assessed as cell count in log phase at 100 ug/ml after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID633948 | Antibacterial activity against Escherichia coli ATCC 35210 incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID555676 | Antimicrobial activity against Escherichia coli DH5[alpha] harboring phagemid pBK-CMV by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg. |
| AID1060488 | Antibacterial activity against Escherichia coli assessed as growth inhibition after 24 hrs by broth dilution method | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1 | Preparation of 8-hydroxyquinoline derivatives as potential antibiotics against Staphylococcus aureus. |
| AID333997 | Antibacterial activity against Pseudomonas aeruginosa assessed per 100 uL of nutrient broth after 24 hrs by tube broth dilution method | 1997 | Journal of natural products, Oct, Volume: 60, Issue:10 | New steroidal alkaloids from Buxus longifolia. |
| AID530519 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype V isolate 5677-04 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID1436576 | Antibacterial activity against Salmonella typhi MTCC 98 by broth microdilution assay method | 2017 | Bioorganic & medicinal chemistry letters, 02-01, Volume: 27, Issue:3 | Synthesis, identification and in vitro biological evaluation of some novel quinoline incorporated 1,3-thiazinan-4-one derivatives. |
| AID1365608 | Antibacterial activity against Staphylococcus aureus MTCC 96 | 2017 | Bioorganic & medicinal chemistry, 11-01, Volume: 25, Issue:21 | Recently reported biological activities of pyrazole compounds. |
| AID324173 | Antibacterial activity against Escherichia coli K12 mutant JHU313 at 6 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID496398 | Antibacterial activity against azide-resistant Escherichia coli J53 TET1 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID542771 | Antimicrobial activity against Escherichia coli J53 transformed with pHND3 carrying qnrB6 gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. |
| AID324295 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoR mutant assessed as cell count in stationary phase at 100 ug/ml after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID529895 | Antimicrobial activity against Leptospira interrogans serovar Icterohaemorrhagiae isolate 3 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID1868234 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as inhibition of bacterial growth | |||
| AID681115 | TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in Caco-2 cells | 2005 | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, Jan, Volume: 59, Issue:1 | Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1. |
| AID360053 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as lactoyl tetra-peptide level | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID161938 | In vitro inhibitory activity against Pneumococci EryRc (34);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID322747 | Inhibition of Escherichia coli MC4100 DnaK assessed as effect on luciferase refolding | 2007 | The Journal of biological chemistry, Feb-16, Volume: 282, Issue:7 | Fatty acyl benzamido antibacterials based on inhibition of DnaK-catalyzed protein folding. |
| AID745307 | Antibacterial activity against Clostridium tetani MTCC 449 assessed as growth inhibition after overnight incubation by NCCLS broth microdilution method | 2013 | European journal of medicinal chemistry, May, Volume: 63 | Synthesis and identification of β-aryloxyquinoline based diversely fluorine substituted N-aryl quinolone derivatives as a new class of antimicrobial, antituberculosis and antioxidant agents. |
| AID584331 | Antibacterial activity against tolC, speE deficient Escherichia coli GD106 | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Interplay between drug efflux and antioxidants in Escherichia coli resistance to antibiotics. |
| AID548742 | Antimicrobial activity against Vancomycin-nonsusceptible Enterococcus faecalis assessed as percent susceptible isolate by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID529197 | Antibacterial activity against ESBL-producing Escherichia coli assessed as resistant isolates by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Comparison of antimicrobial resistance profiles among extended-spectrum-beta-lactamase-producing and acquired AmpC beta-lactamase-producing Escherichia coli isolates from Canadian intensive care units. |
| AID278256 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS9 with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID573344 | Antibacterial activity against ceftazidime-nonsusceptible Citrobacter freundii assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID522366 | Antimicrobial activity against wild type Proteus mirabilis N2 mutant after 16 to 18 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Proteus mirabilis pmrI, an RppA-regulated gene necessary for polymyxin B resistance, biofilm formation, and urothelial cell invasion. |
| AID1379750 | Antimicrobial activity against Escherichia coli incubated for 24 hrs by serial dilution method | 2017 | European journal of medicinal chemistry, Nov-10, Volume: 140 | Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of cyclopenta(hepta)[b]thiophene and fused cyclohepta[b]thiophene analogs. |
| AID324176 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 at 1.5 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID324240 | Antibacterial activity against Escherichia coli K12 containing PhoU mutant assessed as cell count in log phase at 100 ug/ml after 10 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID425597 | Antibacterial activity against extracellular Escherichia coli isolate HM605 isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as colony count at 0.1 to 100 ug/ml after 3 hrs | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID1287094 | Antimicrobial activity against antibiotic resistant Candida albicans clinical isolate 08022710 after 16 hrs by broth dilution method | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis. |
| AID1551863 | Antibacterial activity against Bacillus cereus | 2019 | European journal of medicinal chemistry, Jul-15, Volume: 174 | 1,2,4-Triazole-quinoline/quinolone hybrids as potential anti-bacterial agents. |
| AID255552 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 64.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID531599 | Antimicrobial activity against Klebsiella pneumoniae Kp2792 expressing beta-lactamase SHV-56 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae. |
| AID544271 | Antimicrobial activity against Enterococcus faecalis NKH1 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID255517 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 0.5 uM/ml in dimethylformamide, + = resistant | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID547771 | Antimicrobial activity against Escherichia coli DH10B harboring plasmid pBC SK(+) carrying wild type beta-lactamase KPC-2 by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID568333 | Antimicrobial activity against multidrug-resistant Pseudomonas aeruginosa by broth dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 21, Issue:4 | Design and synthesis of potent Gram-negative specific LpxC inhibitors. |
| AID489652 | Antibacterial activity against Staphylococcus epidermidis ATCC 14990 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID495799 | Ratio of Kcat to Km of KPC-2 using nitrocefin hydrolysis | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Novel ambler class A carbapenem-hydrolyzing beta-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France. |
| AID1868103 | Antibacterial activity against Mycobacterium smegmatis ATCC 607 assessed as inhibition of visible bacterial growth incubated for 48 hrs by CLSI protocol based assay | 2022 | Journal of natural products, 05-27, Volume: 85, Issue:5 | Enceleamycins A-C, Furo-Naphthoquinones from |
| AID382817 | Antimicrobial activity against Staphylococcus aureus ATCC 19433 | 2008 | European journal of medicinal chemistry, Mar, Volume: 43, Issue:3 | Synthesis and biological evaluation of some thiazolyl and thiadiazolyl derivatives of 1H-pyrazole as anti-inflammatory antimicrobial agents. |
| AID531603 | Antimicrobial activity against Escherichia coli JM109 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae. |
| AID1916811 | Antibacterial activity against Staphylococcus aureus NCIM 2010 assessed as bacterial growth inhibition incubated for 8 hrs by absorbance based assay | 2022 | European journal of medicinal chemistry, Aug-05, Volume: 238 | Recent contribution of medicinally active 2-aminothiophenes: A privileged scaffold for drug discovery. |
| AID300201 | Antibacterial activity against Streptococcus pyogenes at 200 mg/mL after 24 hrs by disc diffusion method | 2007 | Bioorganic & medicinal chemistry, Aug-15, Volume: 15, Issue:16 | Identification of antibacterial and antiviral activities of novel fused 1,2,4-triazine esters. |
| AID1491082 | Antibacterial activity against Escherichia coli ATCC 35270 after 24 hrs by serial two fold dilution method | 2017 | Journal of natural products, 05-26, Volume: 80, Issue:5 | Manzamine Alkaloids from an Acanthostrongylophora sp. Sponge. |
| AID278553 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium longum ATCC 15708 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID548481 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 after 48 hrs by Etest in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID569262 | Antimicrobial activity against Escherichia coli DH5alpha | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives. |
| AID1412923 | Antibacterial activity against drug-resistant Pseudomonas aeruginosa PAO1 by microdilution method | 2018 | MedChemComm, May-01, Volume: 9, Issue:5 | Design, synthesis and antimicrobial activity of usnic acid derivatives. |
| AID1545444 | Antibacterial activity against Staphylococcus aureus assessed as zone inhibition at 500 ug/ml by cup plate agar diffusion method | 2019 | Bioorganic & medicinal chemistry, 04-01, Volume: 27, Issue:7 | Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances. |
| AID324220 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 assessed as cell count in log phase at 100 ug/ml after 3 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID735979 | Antimicrobial activity against Botrytis fabae at 1 mg/mL after 48 hrs by agar disc diffusion method | 2013 | European journal of medicinal chemistry, Feb, Volume: 60 | Synthesis and antimicrobial activity of some new benzo and naphthonitrile derivatives. |
| AID1868102 | Antibacterial activity against Listeria monocytogenes ATCC19111 assessed as inhibition of visible bacterial growth incubated for 18 hrs by CLSI protocol based assay | 2022 | Journal of natural products, 05-27, Volume: 85, Issue:5 | Enceleamycins A-C, Furo-Naphthoquinones from |
| AID568824 | Antimicrobial activity against Bordetella bronchiseptica ATCC 4617 at 25 ug/ml by agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis of 4H-chromene, coumarin, 12H-chromeno[2,3-d]pyrimidine derivatives and some of their antimicrobial and cytotoxicity activities. |
| AID422497 | Ratio of Kcat to Km of Carnobacterium divergens BM4489 penicillinase Cad-1 | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens. |
| AID324172 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 at 6 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID548523 | Antimicrobial activity against Vancomycin-susceptible Enterococcus faecium assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. |
| AID540209 | Volume of distribution at steady state in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID1755802 | Antibacterial activity against Escherichia coli ATCC 8739 incubated for 24 hrs by broth microdilution method | 2021 | European journal of medicinal chemistry, Jan-15, Volume: 210 | Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective. |
| AID442401 | Antimicrobial activity against Micrococcus flavus at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID528525 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B6 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID1265688 | Toxicity in Pseudoalteromonas lipolytica TC8 assessed as growth inhibition at 100 uM after 15 hrs by Syto61 based-fluorescence analysis relative to control | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Click-based synthesis of bromotyrosine alkaloid analogs as potential anti-biofilm leads for SAR studies. |
| AID529628 | Antibacterial activity against Beta-lactamase positive Haemophilus influenzae harboring fst1 mutant gene assessed as susceptible isolates after 20 to 24 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID548255 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSn mutant gene after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID285204 | Antimicrobial activity against Escherichia coli AG112 mutant with AG100 marR genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID583096 | Antimicrobial activity against Escherichia coli XL1-Blue harboring pLBII-VIM-2 plasmid expressing VIM-2 W87F mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID544285 | Antimicrobial activity against Enterococcus faecalis NKH15 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID565438 | Antimicrobial activity against Streptococcus intermedius SI006 biofilm harboring luxS mutant gene assessed as biofilm bacterial count at 0.02 ug/ml (Rvb =310.8 +/- 17.10 10'5 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID1870147 | Antibacterial activity against wild type Staphylococcus aureus 4482/A assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID399618 | Antimicrobial activity against Salmonella Typhimurium ATCC 14028 at 0.1 mg/disk by disk diffusion assay | |||
| AID559899 | Antimicrobial activity against Klebsiella pneumoniae 101A harboring beta-lactamase CMY-2 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | First detection of plasmid-encoded blaOXY beta-lactamase. |
| AID318664 | Antibacterial activity against Propionibacterium acnes GAI 5568 by broth microdilution method | 2008 | Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7 | Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens. |
| AID555482 | Ratio of MIC for Acinetobacter genomosp. 3 isolate 103 to MIC for Acinetobacter genomosp. 3 isolate 103 in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID758274 | Antibacterial activity against Staphylococcus aureus MTCC 96 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Design and synthesis of biquinolone-isoniazid hybrids as a new class of antitubercular and antimicrobial agents. |
| AID543800 | Bactericidal activity against Haemophilus influenzae VT450-2006 assessed as eradication of pre-formed biofilm at 1 to 10 times MIC after 24 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Effect of DNase and antibiotics on biofilm characteristics. |
| AID530052 | Antimicrobial activity against Staphylococcus aureus RN4220 expressing gyrB D437N mutant gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. |
| AID1056540 | Antibacterial activity against Staphylococcus aureus ATCC 29213 by broth microdilution method | 2013 | Journal of natural products, Dec-27, Volume: 76, Issue:12 | Cytotoxic and antibacterial marfuraquinocins from the deep South China Sea-derived Streptomyces niveus SCSIO 3406. |
| AID318721 | Antimicrobial activity against Saccharomyces cerevisiae ATCC 9763 upto 100 ug/ml by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID574167 | Antibacterial activity against Escherichia coli MG1655 grown as planktonic cells after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID548017 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237D mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID1224742 | Antimicrobial activity against Candida albicans MTCC 227 by broth microdilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Ultrasound-assisted one-pot four-component synthesis of novel 2-amino-3-cyanopyridine derivatives bearing 5-imidazopyrazole scaffold and their biological broadcast. |
| AID568673 | Antimicrobial activity against Bacillus subtilis ATCC 6633 assessed as growth inhibition at 10 ug/ml by agar dilution method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and structure-activity relationship of 2-thiopyrimidine-4-one analogs as antimicrobial and anticancer agents. |
| AID1423474 | Antibacterial activity against Enterococcus faecium ATCC 19434 after 24 hrs by bacterial proliferation assay | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID1467595 | Antibacterial activity against Bacillus subtilis NBRC 13719 after 12 hrs by MTT assay | 2017 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 27, Issue:14 | New merosesquiterpenes from a Vietnamese marine sponge of Spongia sp. and their biological activities. |
| AID371352 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs | 2009 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 19, Issue:3 | Synthesis and antimicrobial activities of halogenated bis(hydroxyphenyl)methanes. |
| AID524968 | Antibacterial activity against vancomycin-resistant and teichoplanin-susceptible Enterococcus faecalis clinical isolate by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Comparative surveillance study of telavancin activity against recently collected gram-positive clinical isolates from across the United States. |
| AID1290446 | Antifungal activity against Aspergillus fumigatus MTCC 3008 after 24 to 48 hrs by broth microdilution method | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities. |
| AID313668 | Antibacterial activity against Proteus vulgaris ATCC 3851 after 24 hrs | 2008 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 18, Issue:1 | Antimicrobial activities of the bromophenols from the red alga Odonthalia corymbifera and some synthetic derivatives. |
| AID532982 | Antibacterial activity against Escherichia coli W3110 in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID564818 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus hominis assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1399504 | Bactericidal activity against Escherichia coli ATCC 35210 by INT dye based microdilution assay | 2018 | Bioorganic & medicinal chemistry, 09-01, Volume: 26, Issue:16 | 5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation. |
| AID334243 | Antimicrobial activity against Staphylococcus aureus NCIMB 9515 after 24 hrs by microdilution technique | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4 | Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline. |
| AID567774 | Antimicrobial activity against Micrococcus luteus ATCC 10240 assessed as >99.9 % reduction in CFU after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID723724 | Antibacterial activity against Bacillus cereus clinical isolate after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID600685 | Bactericidal activity against Escherichia coli ATCC 35210 after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID1304325 | Antibacterial activity against methicillin-resistant Staphylococcus aureus USA300 SF8300 assessed as growth inhibition after 18 to 20 hrs by microdilution assay | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | Caged xanthones: Potent inhibitors of global predominant MRSA USA300. |
| AID548475 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm, graRm mutant gene after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID1594840 | Bactericidal activity against Listeria monocytogenes NCTC 7973 by microdilution method | 2019 | Journal of natural products, 06-28, Volume: 82, Issue:6 | Antibacterial and Antibiofilm Activity of Flavonoid and Saponin Derivatives from Atriplex tatarica against Pseudomonas aeruginosa. |
| AID69332 | Minimum inhibitory concentration of Ampicillin required for growth inhibition of Beta lactamase producing bacteria Clinically isolated Escherichia coli (TH-397) | 1987 | Journal of medicinal chemistry, Aug, Volume: 30, Issue:8 | Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives. |
| AID587979 | Antibacterial activity against Escherichia coli AS226 carrying pBSDN104D mutant after 18 hrs by broth microdilution method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID625281 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID520996 | Antimicrobial activity against Burkholderia pseudomallei BURK003(1026b) after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Novel antimicrobial peptides that exhibit activity against select agents and other drug resistant bacteria. |
| AID1870154 | Antibacterial activity against wild type Staphylococcus aureus 4679/B assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID405311 | Antibacterial activity against beta-lactamase producing amoxicillin-clavulanic acid-resistant Haemophilus influenzae isolate assessed as percent susceptible isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID585439 | Antimicrobial activity against ampGh1 deficient Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID93879 | Minimum inhibitory concentration against aerobic organism Klebsiella pneumoniae strain 2882 | 1982 | Journal of medicinal chemistry, Apr, Volume: 25, Issue:4 | Quaternary heterocyclylamino beta-lactams: a generic alternative to the classical acylamino side chain. |
| AID210399 | Minimum inhibitory concentration against aerobic organism Streptococcus pyogenes strain 3124 | 1982 | Journal of medicinal chemistry, Apr, Volume: 25, Issue:4 | Quaternary heterocyclylamino beta-lactams: a generic alternative to the classical acylamino side chain. |
| AID1127995 | Toxicity in Staphylococcus aureus ATCC 25923 after 24 hrs by microdilution method | 2014 | Journal of medicinal chemistry, Mar-27, Volume: 57, Issue:6 | First identification of boronic species as novel potential inhibitors of the Staphylococcus aureus NorA efflux pump. |
| AID736480 | Antibacterial activity against Staphylococcus aureus RCMB 010027 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID554990 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 65 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID564834 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus hominis assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID759382 | Antibacterial activity against Bacillus cereus NCTC 14579 assessed as growth inhibition after 24 hrs by Kirby-Bauer disc diffusion method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis and biological evaluation of some novel thiazole compounds as potential anti-inflammatory agents. |
| AID395813 | Antibacterial activity against Bacillus cereus ATCC 14579 at 300 ug/disk after 24 hrs by paper disk diffusion test | 2008 | European journal of medicinal chemistry, Nov, Volume: 43, Issue:11 | Synthesis and biological evaluation of diversely substituted indolin-2-ones. |
| AID559331 | Antimicrobial activity against Shigella flexneri harboring oxa-1-like gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID623616 | Antibacterial activity against 10'8 CFU/mL Escherichia coli MTCC 443 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID419829 | Antibacterial activity against Klebsiella pneumoniae MTCC 109 at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Jun, Volume: 44, Issue:6 | Physicochemical and biological characterization of novel macrocycles derived from o-phthalaldehyde. |
| AID532032 | Antimicrobial activity against Escherichia coli TOP10F' by disk diffusion method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Novel chromosome-encoded CTX-M-78 beta-lactamase from a Kluyvera georgiana clinical isolate as a putative origin of CTX-M-25 subgroup. |
| AID324296 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoBR mutant assessed as cell count in log phase at 100 ug/ml after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID565625 | Antimicrobial activity against Streptococcus intermedius SI006 planktonic cells harboring luxS mutant gene assessed as bacterial count at 0.10 ug/ml in presence of 0.8 nM autoinducer 4,5-dihydroxy-2,3-pentanedione (Rvb =793.3 +/- 42.40 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID1471048 | Antibacterial activity against Bacillus subtilis NCIM 2162 measured after 12 hrs | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID255535 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 1.0 uM/ml in dimethylformamide, + = resistant | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID374021 | Ratio of Kcat to Km for Serratia fonticola UTAD54 SFC1 beta lactamase expressed in Escherichia coli BL21(DE3) by SDS-PAGE | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase. |
| AID544276 | Antimicrobial activity against Enterococcus faecalis NKH6 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID318705 | Antimicrobial activity against Bacillus megaterium by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID555469 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 103 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID463416 | Antimicrobial activity against Klebsiella pneumoniae after 24 hrs by liquid dilution method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines. |
| AID1168634 | Antimicrobial activity against Escherichia coli ATCC 35218 at 10 ug after 18 hrs by agar well diffusion assay | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Phosphorus-nitrogen compounds. Part 29. Syntheses, crystal structures, spectroscopic and stereogenic properties, electrochemical investigations, antituberculosis, antimicrobial and cytotoxic activities and DNA interactions of ansa-spiro-ansa cyclotetrapho |
| AID395357 | Antibacterial activity against Micrococcus luteus La 2971 at 1 ug after 24 hrs by disk diffusion method | 2009 | European journal of medicinal chemistry, Jan, Volume: 44, Issue:1 | Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. |
| AID662082 | Antibacterial activity against Vibrio harveyi after 20 hrs by liquid growth inhibition assay | 2012 | Journal of medicinal chemistry, Mar-08, Volume: 55, Issue:5 | From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity. |
| AID1652709 | Induction of Escherichia coli K12 MG1655 sulA promotor measured at 30 mins interval for 20 hrs by fluorescence assay relative to control | |||
| AID1551864 | Antibacterial activity against Mycobacterium smegmatis | 2019 | European journal of medicinal chemistry, Jul-15, Volume: 174 | 1,2,4-Triazole-quinoline/quinolone hybrids as potential anti-bacterial agents. |
| AID555266 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 109 by Etest method in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID585428 | Antimicrobial activity against oqxAB positive Escherichia coli C600 SW8-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1159096 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as zone of inhibition at 10 mg for 24 hrs at 37 degC by disk diffusion test | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID1769956 | Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC49800 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID585677 | Antimicrobial activity against ampG deficient Pseudomonas aeruginosa PAO1 harboring pZY0901 conferring resistance to gentamycin after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID521324 | Antimicrobial activity against beta lactamase-nonproducing ampicillin-resistant Haemophilus influenzae MSC06647 isolate harboring Asn526Lys mutation in penicillin-binding protein 3 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Comparison of the efficacies of oral beta-lactams in selection of Haemophilus influenzae transformants with mutated ftsI genes. |
| AID583432 | Antimicrobial activity against methicillin-, tetracycline-susceptible and chromosomal mecA deficient Staphylococcus aureus COLnex | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | A mecA-negative strain of methicillin-resistant Staphylococcus aureus with high-level β-lactam resistance contains mutations in three genes. |
| AID585670 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1439803 | Antibacterial activity against Pseudomonas aeruginosa MTCC 102 incubated for 24 hrs under dark condition by microwell dilution method | 2017 | Bioorganic & medicinal chemistry letters, 04-01, Volume: 27, Issue:7 | Biologically active perspective synthesis of heteroannulated 8-nitroquinolines with green chemistry approach. |
| AID420218 | Antimicrobial activity against multidrug-resistant Staphylococcus aureus H.C. 20981 isolate after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID546940 | Antibacterial activity against Salmonella enterica serovar Newport assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID559351 | Antimicrobial activity against Salmonella spp. harboring carb-like gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID565017 | Antimicrobial activity against methicillin-susceptible coagulase-negative Staphylococcus sciuri assessed as susceptible isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID644240 | Antibacterial activity against Escherichia coli clinical isolate after 16 to 20 hrs by two fold agar dilution method | 2012 | European journal of medicinal chemistry, Mar, Volume: 49 | Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2. |
| AID530287 | Antimicrobial activity against PR-39-resistant sbmA-deficient Salmonella enterica serovar Typhimurium LT2 DA12088 by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2. |
| AID1168641 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 at 10 ug after 18 hrs by agar well diffusion assay | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Phosphorus-nitrogen compounds. Part 29. Syntheses, crystal structures, spectroscopic and stereogenic properties, electrochemical investigations, antituberculosis, antimicrobial and cytotoxic activities and DNA interactions of ansa-spiro-ansa cyclotetrapho |
| AID671474 | Antibacterial activity against Staphylococcus haemolyticus ATCC 29970 after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Aug-01, Volume: 20, Issue:15 | Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. |
| AID245276 | Minimum inhibitory concentration required for antifungal activity against Candida albicans ATCC 10321; Not tested | 2004 | Bioorganic & medicinal chemistry letters, Aug-16, Volume: 14, Issue:16 | Synthesis and QSAR studies of pyrimido[4,5-d]pyrimidine-2,5-dione derivatives as potential antimicrobial agents. |
| AID1408107 | Antibacterial activity against Pseudomonas aeruginosa PAO1 after 24 hrs by two-fold serial dilution method | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157 | Design, synthesis, antimicrobial, antiquorum-sensing and antitumor evaluation of new series of pyrazolopyridine derivatives. |
| AID530341 | Ratio of Kcat to Km for Pseudomonas aeruginosa VIM-1 beta-lactamase | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain. |
| AID1769960 | Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC49008 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID322736 | Antimicrobial activity against Escherichia coli MC4100 at 42 degC | 2007 | The Journal of biological chemistry, Feb-16, Volume: 282, Issue:7 | Fatty acyl benzamido antibacterials based on inhibition of DnaK-catalyzed protein folding. |
| AID1303895 | Antibacterial activity against multidrug resistant Pseudomonas aeruginosa NCTC 10332 (ATCC 10145) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID530342 | Ratio of Kcat to Km for Pseudomonas aeruginosa VIM-13 beta-lactamase | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain. |
| AID535750 | Antimicrobial activity against hospital-acquired Escherichia coli expressing extended spectrum beta-lactamase obtained from patient with intra-abdominal infection assessed as susceptible isolates by EUCAST method in presence of beta-lactamase inhibitor Su | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Incidence and antimicrobial susceptibility of Escherichia coli and Klebsiella pneumoniae with extended-spectrum beta-lactamases in community- and hospital-associated intra-abdominal infections in Europe: results of the 2008 Study for Monitoring Antimicrob |
| AID1527470 | Antimicrobial activity against Escherichia coli MTCC 443 assessed as reduction in microbial growth after 24 to 48 hrs by broth dilution method | 2020 | European journal of medicinal chemistry, Jan-01, Volume: 185 | Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents. |
| AID442404 | Antimicrobial activity against Pseudomonas aeruginosa at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1551813 | Antibacterial activity against Pseudomonas aeruginosa | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID556560 | Antimicrobial activity against Escherichia coli K-12 BW25113 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID43737 | Beta-lactamase inhibitory activity against penicillinase of Klebsiella pneumoniae. TN1698 | 1983 | Journal of medicinal chemistry, May, Volume: 26, Issue:5 | Synthesis and biological activities of the Z isomers of carbapenem antibiotics. |
| AID573393 | Antibacterial activity against ceftazidime-susceptible Providencia sp. assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID530237 | Antimicrobial activity against wild-type Mycobacterium smegmatis SMR5 by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID1577953 | Antimicrobial activity against Pseudomonas aeruginosa PA4 under iron-deficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID662084 | Antibacterial activity against Vibrio aestuarianus after 20 hrs by liquid growth inhibition assay | 2012 | Journal of medicinal chemistry, Mar-08, Volume: 55, Issue:5 | From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity. |
| AID1423470 | Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured rhodanese refolding after 45 mins by spectrometric analysis | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID585854 | Antimicrobial activity against Pseudomonas aeruginosa isolate 7 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID558784 | Antimicrobial activity against Enterobacter aerogenes assessed as percent susceptible isolates by CLSI method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007. |
| AID405824 | Antimicrobial activity against Acinetobacter baumannii 696 isolate harboring bla IMP-1 carrying integron In86 containing aminoglycoside resistance gene aac(6')-3 | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Characterization of an integron carrying blaIMP-1 and a new aminoglycoside resistance gene, aac(6')-31, and its dissemination among genetically unrelated clinical isolates in a Brazilian hospital. |
| AID1908123 | Antibacterial activity against Enterococcus faecalis ATCC 29212 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID325449 | Antibacterial activity against Staphylococcus aureus ATCC 3556 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID633457 | Antibacterial activity against Staphylococcus aureus ATCC 6538p after 24 hrs by two fold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial activity of brominated resorcinol dimers. |
| AID489653 | Antibacterial activity against Bacillus cereus ATCC 13061 after 24 hrs by broth microdilution technique | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | New 6-amino-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b] [1,3,4]thiadiazin-6-ones: synthesis, characterization and antibacterial activity evaluation. |
| AID530514 | Antimicrobial activity against group B Streptococcus sp. 'group B' isolate 4214-03 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID1908127 | Antibacterial activity against Escherichia coli ATCC 8739 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID640495 | Antibacterial activity against Micrococcus luteus IFO 12708 | 2012 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 22, Issue:2 | Bioactive lipids from the sponge Spirastrella abata. |
| AID471912 | Antibacterial activity against Staphylococcus aureus MTCC 1144 at 64 ug/ml after 16 hrs by disc diffusion method | 2009 | European journal of medicinal chemistry, Sep, Volume: 44, Issue:9 | A facile one-pot green synthesis and antibacterial activity of 2-amino-4H-pyrans and 2-amino-5-oxo-5,6,7,8-tetrahydro-4H-chromenes. |
| AID318716 | Antimicrobial activity against Haemophilus influenzae by broth dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: synthesis and structure-activity relationship. |
| AID665060 | Antibacterial activity against Vibrio cholerae MTCC 3906 after 24 hrs by micro-broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 22, Issue:11 | An efficient one-pot synthesis, structure, antimicrobial and antioxidant investigations of some novel quinolyldibenzo[b,e][1,4]diazepinones. |
| AID1592959 | Antibacterial activity against multi-drug resistant Klebsiella pneumoniae NMI 2697/14 assessed as reduction in microbial growth incubated for 20 hrs | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. |
| AID324308 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 assessed as cell count at 100 ug/ml | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID378239 | Antimicrobial activity against Bacillus subtilis after 48 hrs by paper disk assay | 2000 | Journal of natural products, Nov, Volume: 63, Issue:11 | Metabolites of Colletotrichum gloeosporioides, an endophytic fungus in Artemisia mongolica. |
| AID520872 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus saprophyticus isolate TSU67 isolated from genitourinary tracts of acute cystitis patient after 24 hrs at 35 degC by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Methicillin-resistant Staphylococcus saprophyticus isolates carrying staphylococcal cassette chromosome mec have emerged in urogenital tract infections. |
| AID567775 | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as >99.9 % reduction in CFU after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID392750 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 to 24 hrs by tube dilution method | 2009 | Bioorganic & medicinal chemistry, Feb-15, Volume: 17, Issue:4 | Synthesis and antimicrobial evaluation of some new substituted purine derivatives. |
| AID585197 | Antimicrobial activity against Escherichia coli DH5[alpha] transformed with pAC-ges1 plasmid encoding Beta-lactamase GES-13 K104, N170 mutant by Etest method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Comparative biochemical and computational study of the role of naturally occurring mutations at Ambler positions 104 and 170 in GES β-lactamases. |
| AID322746 | Toxicity against human erythrocytes assessed as hemolytic activity | 2007 | The Journal of biological chemistry, Feb-16, Volume: 282, Issue:7 | Fatty acyl benzamido antibacterials based on inhibition of DnaK-catalyzed protein folding. |
| AID352617 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolates by tube dilution method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Synthesis and in vitro antimicrobial activity of some novel substituted benzimidazole derivatives having potent activity against MRSA. |
| AID467968 | Antimicrobial activity against Staphylococcus epidermidis ATCC 14990 after 18 to 24 hrs by liquid broth method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and evaluation of antibacterial activity of some thiazolo[3,2-b][1,2,4]triazole incorporating diphenylsulfone moieties. |
| AID508594 | Antibacterial activity against ciprofloxacin-susceptible Salmonella enteritidis 1A-revertC2 harboring gyrA D87Y/S83F mutant, parC D79N mutant, soxR R133C/R20H mutant, soxS E52K mutant and marA I111N/H115Q mutant gene after 70 passages by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Fitness costs and stability of a high-level ciprofloxacin resistance phenotype in Salmonella enterica serotype enteritidis: reduced infectivity associated with decreased expression of Salmonella pathogenicity island 1 genes. |
| AID1265698 | Toxicity in Pseudoalteromonas ulvae TC14 assessed as effect on viability at 100 uM after 6 hrs by resazurin-staining assay relative to control | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Click-based synthesis of bromotyrosine alkaloid analogs as potential anti-biofilm leads for SAR studies. |
| AID1233740 | Antimicrobial activity against Candida albicans ATCC 10231 assessed as microbial growth inhibition at 1 mg/ml incubated overnight at 37 degC | 2015 | Journal of natural products, Jul-24, Volume: 78, Issue:7 | HPLC-NMR and HPLC-MS Profiling and Bioassay-Guided Identification of Secondary Metabolites from the Australian Plant Haemodorum spicatum. |
| AID495751 | Antimicrobial activity against Escherichia coli J5 transconjugants expressing beta lactamase CTX-M-9 isolated from human flora associated C3H rat infected with Salmonella enterica serotype Virchow by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID1423480 | Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Rosetta(DE3) assessed as reduction in HSP60/HSP10-mediated denatured MDH refolding after 40 to 60 mins by spect | 2018 | Journal of medicinal chemistry, 12-13, Volume: 61, Issue:23 | Hydroxybiphenylamide GroEL/ES Inhibitors Are Potent Antibacterials against Planktonic and Biofilm Forms of Staphylococcus aureus. |
| AID531601 | Antimicrobial activity against Escherichia coli JM109 harboring pSC1 plasmid expressing beta-lactamase SHV-56 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Oct, Volume: 52, Issue:10 | Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae. |
| AID1209734 | Inhibition of mouse OAT1 expressed in CHO cells assessed as inhibition of fluorescein uptake at 500 uM over 20 mins relative to untreated-control | 2013 | Drug metabolism and disposition: the biological fate of chemicals, Apr, Volume: 41, Issue:4 | Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics. |
| AID424716 | Antifungal activity against Candida albicans | 2009 | Journal of natural products, Apr, Volume: 72, Issue:4 | Limazepines A-F, pyrrolo[1,4]benzodiazepine Antibiotics from an Indonesian Micrococcus sp. |
| AID678538 | Antibacterial activity against Salmonella typhi ATCC 700931 | 2012 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 22, Issue:18 | Design, solvent free synthesis, and antimicrobial evaluation of 1,4 dihydropyridines. |
| AID504048 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 1688 by broth microdilution technique | 2010 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 20, Issue:18 | Synthesis and antimicrobial activity of novel fluorine containing 4-(substituted-2-hydroxybenzoyl)-1H-pyrazoles and pyrazolyl benzo[d]oxazoles. |
| AID203341 | Minimum inhibitory concentration against aerobic organism Shigella species strain 2880 | 1982 | Journal of medicinal chemistry, Apr, Volume: 25, Issue:4 | Quaternary heterocyclylamino beta-lactams: a generic alternative to the classical acylamino side chain. |
| AID427673 | Antimicrobial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by dilution susceptibility assay | 2009 | Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13 | Synthesis and antimicrobial activity of 4-hydroxy-4-(pyridyl)alk-3-en-2-ones. |
| AID372560 | Antibacterial activity against genetically beta-lactamase-negative ampicillin-resistant Haemophilus influenzae type b with an amino acid substitution in variable mutated locus Asn-526 or Arg-517 of ftsI gene assessed as resistance rate by broth microdilut | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Genetic characteristics and clonal dissemination of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains isolated from the upper respiratory tract of patients in Japan. |
| AID495326 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with Gly490Glu, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID278235 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-1 tolC::Kan with GyrA S83F mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID519663 | Antimicrobial activity against Escherichia coli Irk1224 harboring beta-lactamase CTX-M-3 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Convergent in vivo and in vitro selection of ceftazidime resistance mutations at position 167 of CTX-M-3 beta-lactamase in hypermutable Escherichia coli strains. |
| AID300437 | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 24 hrs by broth microdilution test | 2007 | Bioorganic & medicinal chemistry, Sep-01, Volume: 15, Issue:17 | 1-Acylthiosemicarbazides, 1,2,4-triazole-5(4H)-thiones, 1,3,4-thiadiazoles and hydrazones containing 5-methyl-2-benzoxazolinones: synthesis, analgesic-anti-inflammatory and antimicrobial activities. |
| AID558317 | Antibacterial activity against Campylobacter jejuni assessed as resistant isolates by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID1399280 | Antimicrobial activity against Escherichia coli ATCC 25922 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID520874 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus saprophyticus isolate TSU90 isolated from genitourinary tracts of acute cystitis patient after 24 hrs at 35 degC by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Methicillin-resistant Staphylococcus saprophyticus isolates carrying staphylococcal cassette chromosome mec have emerged in urogenital tract infections. |
| AID1132057 | Cytotoxicity against BHK cells | 1978 | Journal of medicinal chemistry, Jan, Volume: 21, Issue:1 | Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. |
| AID614155 | Antimicrobial activity against Proteus vulgaris ATCC 3851 | 2011 | Journal of natural products, Aug-26, Volume: 74, Issue:8 | Sesterterpenes from the tropical sponge Coscinoderma sp. |
| AID1331873 | Antibacterial activity against Acinetobacter baumannii ATCC 19606 | 2017 | Bioorganic & medicinal chemistry, 01-01, Volume: 25, Issue:1 | Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. |
| AID525550 | Antimicrobial activity against ampicillin resistant serotype-e Haemophilus influenzae isolate BB1053 harboring with plasmid pB1000 bearing beta-lactamase ROB-1 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Apr, Volume: 54, Issue:4 | Haemophilus influenzae clinical isolates with plasmid pB1000 bearing blaROB-1: fitness cost and interspecies dissemination. |
| AID582899 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87M mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1104313 | Antibacterial activity against Staphylococcus aureus ATCC 6538 at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID1168628 | Antimicrobial activity against Escherichia coli ATCC 25922 at 10 ug after 18 hrs by agar well diffusion assay | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Phosphorus-nitrogen compounds. Part 29. Syntheses, crystal structures, spectroscopic and stereogenic properties, electrochemical investigations, antituberculosis, antimicrobial and cytotoxic activities and DNA interactions of ansa-spiro-ansa cyclotetrapho |
| AID405085 | Ratio of Kcat to Km of Citrobacter freundii PER2 beta lactamase | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Biochemical characterization of PER-2 and genetic environment of blaPER-2. |
| AID557684 | Antimicrobial activity in Prevotella oralis group by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1304337 | Bactericidal activity against methicillin-susceptible Staphylococcus aureus ATCC 29213 after 18 to 20 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | Caged xanthones: Potent inhibitors of global predominant MRSA USA300. |
| AID1287089 | Antimicrobial activity against antibiotic resistant Candida albicans clinical isolate 08030809 after 16 hrs by broth dilution method | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis. |
| AID573366 | Antibacterial activity against ceftazidime-susceptible Morganella morganii assessed as resistant isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID1328337 | Antibacterial activity against Enterobacter aerogenes ATCC 13048 assessed as zone of inhibition at 100 ug/disk measured after 24 hrs by agar disk-diffusion method | 2016 | Journal of natural products, 09-23, Volume: 79, Issue:9 | Halogenated Sesquiterpenoids from the Red Alga Laurencia tristicha Collected in Taiwan. |
| AID477030 | Antifungal activity against Fusarium oxysporum at 2 mg/ml after 7 days by agar diffusion assay | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and antimicrobial activities of some new thiazole and pyrazole derivatives based on 4,5,6,7-tetrahydrobenzothiophene moiety. |
| AID547172 | Antibacterial activity against Plesiomonas shigelloides assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID547770 | Antimicrobial activity against Escherichia coli DH10B harboring plasmid pBC SK(+) carrying wild type beta-lactamase KPC-2 by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID357357 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by agar dilution method | 2001 | Journal of natural products, Aug, Volume: 64, Issue:8 | Verbalactone, a new macrocyclic dimer lactone from the roots of Verbascum undulatum with antibacterial activity. |
| AID1868100 | Antibacterial activity against Bacillus subtilis ATCC 6633 assessed as inhibition of visible bacterial growth incubated for 18 hrs by CLSI protocol based assay | 2022 | Journal of natural products, 05-27, Volume: 85, Issue:5 | Enceleamycins A-C, Furo-Naphthoquinones from |
| AID542587 | Antimicrobial activity against Acinetobacter radioresistens 251-39C expressing beta-lactamase OXA-133 by CLSI method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Codetection of blaOXA-23-like gene (blaOXA-133) and blaOXA-58 in Acinetobacter radioresistens: report from the SENTRY antimicrobial surveillance program. |
| AID287239 | Antimicrobial activity against Staphylococcus aureus IFO 3060 after 24 hrs | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles. |
| AID278532 | Antimicrobial activity against Bifidobacterium thermophilum ATCC 25866 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID494163 | Antibacterial activity against Escherichia coli after 24 hrs by disc diffusion method | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, characterization, in vitro and molecular docking studies of new 2,5-dichloro thienyl substituted thiazole derivatives for antimicrobial properties. |
| AID584481 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN11 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID1265202 | Bactericidal activity against methicillin-resistant Staphylococcus aureus NCTC 13616 after 24 hrs | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes. |
| AID1326385 | Antibacterial activity against Bacillus subtilis P10A derived after 10 passage in presence of JBIR-100 after 16 to 18 hrs by microbroth dilution assay | 2016 | Bioorganic & medicinal chemistry, 12-15, Volume: 24, Issue:24 | Biological characterization of the hygrobafilomycin antibiotic JBIR-100 and bioinformatic insights into the hygrolide family of natural products. |
| AID585453 | Antimicrobial activity against ampD, ampDh2, ampDh3 and ampG deficient Pseudomonas aeruginosa PAO1 harboring pZY0901 conferring resistance to gentamycin after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID655621 | Antibacterial activity against Burkholderia pseudomallei NTCC 10274 at 80 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID555246 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 60 by Etest method in presence of cloxacillin | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID556565 | Antimicrobial activity against katG gene-deficient Escherichia coli K-12 3157 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID1309069 | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 16 to 20 hrs by agar dilution method | 2016 | Bioorganic & medicinal chemistry, 08-15, Volume: 24, Issue:16 | Novel benzimidazol-2-ylidene carbene precursors and their silver(I) complexes: Potential antimicrobial agents. |
| AID426140 | Antibacterial activity against Escherichia coli ATCC 35218 after 24 hrs by agar well diffusion method | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis and antimicrobial studies of novel methylene bridged benzisoxazolyl imidazo[2,1-b][1,3,4]thiadiazole derivatives. |
| AID585671 | Antimicrobial activity against Pseudomonas aeruginosa PAK after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID405307 | Antibacterial activity against beta-lactamase positive ampicillin resistant Haemophilus influenzae isolate assessed as percent susceptible isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID662076 | Antibacterial activity against Listeria monocytogenes after 20 hrs by liquid growth inhibition assay | 2012 | Journal of medicinal chemistry, Mar-08, Volume: 55, Issue:5 | From a marine neuropeptide to antimicrobial pseudopeptides containing aza-β(3)-amino acids: structure and activity. |
| AID529597 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-10 assessed as inhibition of bacterial growth at 4096 ug/ml after 18 hrs | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID1769953 | Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC 52056 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID161941 | In vitro inhibitory activity against Pneumococci PenR (65);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID324995 | Antibacterial activity against Haemophilus aphrophilus ATCC 33389 by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | Horizontal gene transfer of ftsI, encoding penicillin-binding protein 3, in Haemophilus influenzae. |
| AID585847 | Antimicrobial activity against Pseudomonas aeruginosa isolate 4 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID563973 | Ratio of Kcat to Km for Klebsiella pneumoniae 05-560 beta-lactamase NDM-1 | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. |
| AID590282 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase. |
| AID758269 | Antifungal activity against Candida albicans MTCC 227 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Design and synthesis of biquinolone-isoniazid hybrids as a new class of antitubercular and antimicrobial agents. |
| AID1551861 | Antibacterial activity against Staphylococcus aureus | 2019 | European journal of medicinal chemistry, Jul-15, Volume: 174 | 1,2,4-Triazole-quinoline/quinolone hybrids as potential anti-bacterial agents. |
| AID574172 | Antibacterial activity against Escherichia coli OCL62 grown as biofilms after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID1821097 | Antibacterial activity against Klebsiella pneumoniae ATCC 10031 assessed as inhibition of bacterial growth incubated for 24 hr by CLSI based broth microdilution method | |||
| AID64880 | Influence of porins and TonB on antibacterial activity in Escherichia coli (KB4) using agar diffusion assay | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID1769812 | Antimicrobial activity against Micrococcus luteus ML01 assessed as inhibition of bacterial growth incubated for 16 to 18 hrs by broth micro dilution technique | |||
| AID1243992 | Antimicrobial activity against Staphylococcus citreus by agar dilution method | 2015 | European journal of medicinal chemistry, Aug-28, Volume: 101 | Design and synthesis of some new pyrazolyl-pyrazolines as potential anti-inflammatory, analgesic and antibacterial agents. |
| AID371351 | Antibacterial activity against Staphylococcus aureus ATCC 6538p after 24 hrs | 2009 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 19, Issue:3 | Synthesis and antimicrobial activities of halogenated bis(hydroxyphenyl)methanes. |
| AID562591 | Antimicrobial activity against Enterococcus faecium clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID201742 | In vitro antibacterial activity against SG 621 strain of Serratia marcescens | 2002 | Journal of medicinal chemistry, Jul-04, Volume: 45, Issue:14 | Highly antibacterial active aminoacyl penicillin conjugates with acylated bis-catecholate siderophores based on secondary diamino acids and related compounds. |
| AID278257 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS9 gyrA+ with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID278549 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium breve ATCC 15700 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID735216 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 2488 assessed as growth inhibition measured after overnight incubation by broth dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | New 2-benzylsulfanyl-nicotinic acid based 1,3,4-oxadiazoles: their synthesis and biological evaluation. |
| AID1870151 | Antibacterial activity against wild type Staphylococcus aureus 4717/B assessed as reduction in microbial growth incubated for 24 hrs by microdilution assay | 2022 | Journal of medicinal chemistry, 07-28, Volume: 65, Issue:14 | LEGO-Lipophosphonoxins: A Novel Approach in Designing Membrane Targeting Antimicrobials. |
| AID288607 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 | 2007 | Journal of medicinal chemistry, May-31, Volume: 50, Issue:11 | Antibacterial nicotinamide adenine dinucleotide synthetase inhibitors: amide- and ether-linked tethered dimers with alpha-amino acid end groups. |
| AID1821095 | Antibacterial activity against Enterococcus faecalis ATCC 19433 assessed as inhibition of bacterial growth incubated for 24 hr by CLSI based broth microdilution method | |||
| AID520382 | Antimicrobial activity Escherichia coli DH5alpha harboring bacteriophage T4 plasmid alpha omega by agar macrodilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain. |
| AID559903 | Antimicrobial activity against Escherichia coli TF-KO281 harboring beta-lactamase OXY-1 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | First detection of plasmid-encoded blaOXY beta-lactamase. |
| AID1728304 | Antibacterial activity against Staphylococcus epidermis ATCC 12228 assessed as diameter of inhibition zone at 10 mg/ml by disk diffusion assay | 2021 | European journal of medicinal chemistry, Jan-15, Volume: 210 | Preparation of new 1,3-dibenzyl tetrahydropyridinylidene ammonium salts and their antimicrobial and anticellular activities. |
| AID289242 | Antimicrobial activity against Neisseria gonorrhoeae | 2007 | Bioorganic & medicinal chemistry, Sep-15, Volume: 15, Issue:18 | Utility of 6-amino-2-thiouracil as a precursor for the synthesis of bioactive pyrimidine derivatives. |
| AID594926 | Antibacterial activity against Rhodococcus opacus assessed as growth inhibition at 100 ug/ml after 72 hrs by microplate reader | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Identification of novel potential antibiotics for tuberculosis by in silico structure-based drug screening. |
| AID548474 | Antibacterial activity against vancomycin-susceptible Staphylococcus aureus Mu50omega expressing vraSm mutant gene after 48 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID324289 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoBR mutant assessed as cell count in stationary phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID544279 | Antimicrobial activity against Enterococcus faecalis NKH9 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID582897 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87N mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1141103 | Antimicrobial activity against Enterobacter cloacae ATCC 23355 after 24 to 48 hrs by two-fold broth microdilution method | 2014 | Bioorganic & medicinal chemistry, May-15, Volume: 22, Issue:10 | Exploring 5-nitrofuran derivatives against nosocomial pathogens: synthesis, antimicrobial activity and chemometric analysis. |
| AID590509 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs | 2011 | European journal of medicinal chemistry, Apr, Volume: 46, Issue:4 | Synthesis, biopharmaceutical characterization, antimicrobial and antioxidant activities of 1-(4'-O-β-D-glucopyranosyloxy-2'-hydroxyphenyl)-3-aryl-propane-1,3-diones. |
| AID529577 | Ratio of Kcat to Km for Pseudomonas maltophilia ULA-511 beta-Lactamase L-1 | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora. |
| AID671465 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 24 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry, Aug-01, Volume: 20, Issue:15 | Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. |
| AID582909 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61R mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID562524 | Antimicrobial activity against pbp5 gene-deficient fusidic acid-, rifampin-resistant Enterococcus faecium D344SRF expressing hylEfm gene by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Cotransfer of antibiotic resistance genes and a hylEfm-containing virulence plasmid in Enterococcus faecium. |
| AID565456 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 planktonic cells assessed as bacterial count at 0.10 ug/ml (Rvb =771.7 +/- 35.14 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID1204965 | Antimicrobial activity against Staphylococcus aureus ATCC 6538p after 24 hrs by twofold dilution method | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Additional sesterterpenes and a nortriterpene saponin from the sponge Clathria gombawuiensis. |
| AID633849 | Antibacterial activity against clinical isolate of Bacillus cereus after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID529303 | Antimicrobial activity against Acinetobacter genospecies 3 isolate Ac057 expressing beta-lactamase Oxa-58 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate. |
| AID776462 | Antimicrobial activity against Yersinia pseudotuberculosis ATCC 911 at 10 ug | 2013 | European journal of medicinal chemistry, Nov, Volume: 69 | Design, synthesis and biological activities of some 7-aminocephalosporanic acid derivatives. |
| AID1467596 | Antibacterial activity against Staphylococcus aureus NBRC 100910 after 12 hrs by MTT assay | 2017 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 27, Issue:14 | New merosesquiterpenes from a Vietnamese marine sponge of Spongia sp. and their biological activities. |
| AID1388189 | Antibacterial activity against Escherichia coli MTCC 443 incubated for 24 hrs by serial dilution method | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18 | Synthesis, antimicrobial activity, structure-activity relationship and cytotoxic studies of a new series of functionalized (Z)-3-(2-oxo-2-substituted ethylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ones. |
| AID568332 | Antimicrobial activity against wild type Pseudomonas aeruginosa by broth dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 21, Issue:4 | Design and synthesis of potent Gram-negative specific LpxC inhibitors. |
| AID519107 | Antibacterial activity against Proteus mirabilis B2 after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID1164944 | Antimicrobial activity against tolC-deficient Escherichia coli by microbroth dilution method | 2014 | Journal of medicinal chemistry, Oct-23, Volume: 57, Issue:20 | Synthesis, structure-activity relationship studies, and antibacterial evaluation of 4-chromanones and chalcones, as well as olympicin A and derivatives. |
| AID585873 | Antimicrobial activity against Pseudomonas aeruginosa isolate 17 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID324166 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid PhoU at 100 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID583089 | Ratio of Kcat to Km for Escherichia coli XL1-Blue wild-type VIM-2 beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID520775 | Antibacterial activity against beta-lactamase KPC-2 producing Klebsiella pneumoniae isolate K1 to K9 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. |
| AID352575 | Antimicrobial activity against Yersinia pseudotuberculosis ATCC 911 at 10 ug after 18 hrs by agar-well diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Synthesis of some new 1,2,4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities. |
| AID1132049 | Antibacterial activity against Streptococcus pyogenes CN10 | 1978 | Journal of medicinal chemistry, Jan, Volume: 21, Issue:1 | Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. |
| AID374112 | Antimicrobial activity against azide-resistant aac(6')-Ib-cr expressing Escherichia coli J53 qnrA1 bearing pHS6 transconjugant from Escherichia coli 650 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID426132 | Antibacterial activity against Staphylococcus aureus ATCC 25923 at 100 ug/ml after 24 hrs by agar well diffusion method | 2009 | European journal of medicinal chemistry, Jul, Volume: 44, Issue:7 | Synthesis and antimicrobial studies of novel methylene bridged benzisoxazolyl imidazo[2,1-b][1,3,4]thiadiazole derivatives. |
| AID463403 | Antimicrobial activity against Bacillus subtilis at 1000 ug after 24 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines. |
| AID519106 | Antibacterial activity against Escherichia coli 10418 after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID758271 | Antibacterial activity against Salmonella typhi MTCC 98 assessed as growth inhibition by broth microdilution method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Design and synthesis of biquinolone-isoniazid hybrids as a new class of antitubercular and antimicrobial agents. |
| AID425594 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM605 in mouse J774A1 cells isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as intracellular killing of bacteria at 0.1 to 100 ug/ml af | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID510167 | Antimicrobial activity against Klebsiella pneumoniae RSKK 574 by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID678535 | Antibacterial activity against Escherichia coli ATCC 25922 | 2012 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 22, Issue:18 | Design, solvent free synthesis, and antimicrobial evaluation of 1,4 dihydropyridines. |
| AID666959 | Antibacterial activity against Clostridium tetani MTCC 449 by broth microdilution method | 2012 | European journal of medicinal chemistry, Aug, Volume: 54 | New N-arylamino biquinoline derivatives: synthesis, antimicrobial, antituberculosis, and antimalarial evaluation. |
| AID1399278 | Antimicrobial activity against Escherichia coli isolate SJ 6 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID524593 | Antimicrobial activity against multidrug-resistant Klebsiella pneumoniae isolate Kpn-DK2 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | KPC-producing extreme drug-resistant Klebsiella pneumoniae isolate from a patient with diabetes mellitus and chronic renal failure on hemodialysis in South Korea. |
| AID510158 | Antimicrobial activity against Acinetobacter baumannii RSKK 02026 by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID1286512 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 20 to 24 hrs in presence of 2% heat inactivated bovine serum | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID530507 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype III isolate 3444-99 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID587978 | Antibacterial activity against Escherichia coli AS226 carrying pBSDN104A mutant after 18 hrs by broth microdilution method | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Roles of residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in extended-spectrum beta-lactamase Toho-1. |
| AID548253 | Antibacterial activity against vancomycin-intermediate Staphylococcus aureus Mu50 after 24 hrs by Etest | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. |
| AID668095 | Antibacterial activity against Klebsiella pneumoniae NBRC 3512 after overnight incubation by microdilution method | 2012 | Journal of natural products, Apr-27, Volume: 75, Issue:4 | Phenanthrene derivatives from Cymbidium Great Flower Marie Laurencin and their biological activities. |
| AID1896847 | Antibacterial activity against Staphylococcus aureus ATCC29213 assessed as prevention of visible growth by broth microdilution method | |||
| AID442423 | Antimicrobial activity against Listeria monocytogenes at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID632560 | Antibacterial activity against Bacillus subtilis at 200 ug/mL after 24 hrs by agar cup diffusion method | 2011 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 21, Issue:24 | A new antifungal briarane diterpenoid from the gorgonian Junceella juncea Pallas. |
| AID536142 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by serial dilution method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Design, synthesis and in vitro evaluation of antitubercular and antimicrobial activity of some novel pyranopyrimidines. |
| AID568672 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition at 10 ug/ml by agar dilution method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis and structure-activity relationship of 2-thiopyrimidine-4-one analogs as antimicrobial and anticancer agents. |
| AID324304 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoBR mutant assessed as cell count in log phase at 100 ug/ml after 72 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID324241 | Antibacterial activity against Escherichia coli K12 containing PhoU mutant assessed as cell count in stationary phase at 100 ug/ml after 10 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1408109 | Antifungal activity against Aspergillus fumigatus 293 after 48 hrs by two-fold serial dilution method | 2018 | European journal of medicinal chemistry, Sep-05, Volume: 157 | Design, synthesis, antimicrobial, antiquorum-sensing and antitumor evaluation of new series of pyrazolopyridine derivatives. |
| AID757697 | Antibacterial activity against Escherichia coli ATCC 11775 assessed as growth inhibition after 24 to 48 hrs by kirby-bauer disc diffusion method | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis, antitumor and antibacterial activities of some novel tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives. |
| AID1411620 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hrs by microdilution method | |||
| AID420216 | Antimicrobial activity against Mycobacterium smegmatis UFPEDA 71 after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID563970 | Antibacterial activity against Escherichia coli J53 harboring beta-lactamase NDM-1 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. |
| AID1309067 | Antibacterial activity against Escherichia coli ATCC 25922 after 16 to 20 hrs by agar dilution method | 2016 | Bioorganic & medicinal chemistry, 08-15, Volume: 24, Issue:16 | Novel benzimidazol-2-ylidene carbene precursors and their silver(I) complexes: Potential antimicrobial agents. |
| AID345807 | Antimicrobial activity against Staphylococcus aureus ATCC 6538 | 2008 | Bioorganic & medicinal chemistry, Dec-15, Volume: 16, Issue:24 | Synthesis and antimicrobial activity of 2-alkenylchroman-4-ones, 2-alkenylthiochroman-4-ones and 2-alkenylquinol-4-ones. |
| AID1484009 | Antimicrobial activity against Pseudomonas aeruginosa PAO1 assessed as growth inhibition zone after 18 hrs by disc diffusion method | 2017 | Journal of natural products, 02-24, Volume: 80, Issue:2 | Discovery of C-Glycosylpyranonaphthoquinones in Streptomyces sp. MBT76 by a Combined NMR-Based Metabolomics and Bioinformatics Workflow. |
| AID324171 | Antibacterial activity against Escherichia coli K12 mutant JHU313 containing plasmid vector at 25 ug/ml after 48 hrs by disc diffusion method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID528524 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B1 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID530230 | Antimicrobial activity against Mycobacterium bovis BCG ML1044 carrying transposon IS1096::Km inserted at -178bp of ppe33b gene by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID425865 | Antimicrobial activity against Carnobacterium divergens BM4489 expressing beta-lactamase CAD1 at 0.5 McFarland inoculum size by E-test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens. |
| AID519471 | Antimicrobial activity against Stenotrophomonas maltophilia K279a expressing beta-lactamase L1 and L2 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Induction of L1 and L2 beta-lactamase production in Stenotrophomonas maltophilia is dependent on an AmpR-type regulator. |
| AID1412927 | Bactericidal activity against Staphylococcus aureus ATCC 6538 by microdilution method | 2018 | MedChemComm, May-01, Volume: 9, Issue:5 | Design, synthesis and antimicrobial activity of usnic acid derivatives. |
| AID1411618 | Antibacterial activity against Bacillus cereus after 24 hrs by microdilution method | |||
| AID548040 | Antimicrobial activity against Escherichia coli DH10B harboring plasmid pBK SK(+) by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID1585536 | Antibacterial activity against Escherichia coli assessed as zone of inhibition at 50 ug/ml after 3 days by filter paper disc method | 2019 | European journal of medicinal chemistry, Jan-15, Volume: 162 | Benzofuran derivatives and their anti-tubercular, anti-bacterial activities. |
| AID674910 | Antibacterial activity against Streptococcus pyogenes MTCC 442 | 2012 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 22, Issue:17 | Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives. |
| AID731201 | Antibacterial activity against Vibrio cholerae MTCC 3906 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles. |
| AID561441 | Antibacterial activity against Escherichia coli 1285 harboring beta-lactamase CMY-33 gene by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Reduced susceptibility to cefepime among Escherichia coli clinical isolates producing novel variants of CMY-2 beta-lactamase. |
| AID278250 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS1 acrAB::Kan with GyrA S83F, D87N, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID575420 | Antimicrobial activity against anrB-deficient Listeria monocytogenes EGD-e assessed as growth inhibition after 16 hrs by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | The ABC transporter AnrAB contributes to the innate resistance of Listeria monocytogenes to nisin, bacitracin, and various beta-lactam antibiotics. |
| AID360061 | Inhibition of Enterococcus faecium M512 LDtfm transpeptidase activity assessed as tri-aspartate-tetra-aspartate multimer containing L-Lys3 to D-Asp-L-Lys3 cross links at 8 ug/ml | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID1627346 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as bacterial growth inhibition after 8 hrs by turbidimetric plate reader method | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16 | 1α,2α-Epoxy-3β-hydroxy oleanolic acid derivatives regulation of the metabolism, haemolysis and β-lactamase gene expression in vitro and their structure-microbicidal activity relationship. |
| AID1368638 | Anti-biofilm activity against Pseudoalteromonas lipolytica TC8 assessed as inhibition of bacterial adhesion incubated for 15 hrs at 20 degC by Syto 61 dye based fluorimetric assay | 2018 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 28, Issue:2 | Towards smart biocide-free anti-biofilm strategies: Click-based synthesis of cinnamide analogues as anti-biofilm compounds against marine bacteria. |
| AID1694052 | Antibacterial activity against Escherichia coli ATCC 12435 assessed as diameter of zone inhibition at 5 mg/ml incubated for 24 hrs by agar plate diffusion method | 2021 | Bioorganic & medicinal chemistry, 02-01, Volume: 31 | Synthesis, anticancer and antimicrobial evaluation of new benzofuran based derivatives: PI3K inhibition, quorum sensing and molecular modeling study. |
| AID1762808 | Antibacterial activity against Klebsiella pneumoniae assessed as reduction in bacterial growth incubated for 24 hrs by by broth microdilution method | 2021 | Bioorganic & medicinal chemistry, 05-15, Volume: 38 | Dipyridyl-substituted thiosemicarbazone as a potent broad-spectrum inhibitor of metallo-β-lactamases. |
| AID1287101 | Antimicrobial activity against Escherichia coli ATCC 25922 assessed as inhibition of bacterial growth after 16 hrs by broth dilution method | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | A Designed Tryptophan- and Lysine/Arginine-Rich Antimicrobial Peptide with Therapeutic Potential for Clinical Antibiotic-Resistant Candida albicans Vaginitis. |
| AID677141 | Antimicrobial activity against Staphylococcus aureus by broth microdilution assay | 2012 | Bioorganic & medicinal chemistry, Sep-01, Volume: 20, Issue:17 | Indole alkaloids from two cultured cyanobacteria, Westiellopsis sp. and Fischerella muscicola. |
| AID495331 | Antimicrobial activity against Beta-lactamase-negative, ampicillin-resistant Haemophilus influenzae with Asp350Asn, Met377Ile, Gly490Glu, Ala502Val, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID582904 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87L mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID278566 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium longum P/N 601377 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID545451 | Antimicrobial activity against extended-spectrum beta-lactamase-positive Klebsiella oxytoca assessed as percent susceptible isolates by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Susceptibility of gram-negative pathogens isolated from patients with complicated intra-abdominal infections in the United States, 2007-2008: results of the Study for Monitoring Antimicrobial Resistance Trends (SMART). |
| AID1337841 | Antifungal activity against Candida albicans NCIM 3471 by standard agar method | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Quinolidene-rhodanine conjugates: Facile synthesis and biological evaluation. |
| AID360070 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as tetra -aspartate-tetra multimer containing D-Ala4 to D-Asp-L-Lys3 cross links at 128 ug/ml by mass spectrometry | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID559329 | Antimicrobial activity against Salmonella enterica serovar Virchow assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID625284 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID1617682 | Antibacterial activity against Bacillus subtilis BS01 by CLSI based two-fold serial dilution method | |||
| AID40926 | The compound was tested for minimal inhibitory concentration against Bacillus subtilis | 2002 | Bioorganic & medicinal chemistry letters, Sep-02, Volume: 12, Issue:17 | The activity of p-methoxybenzylisothiocyanate against Neisseria gonorrhoeae, Haemophilus ducreyi, and other microorganisms. |
| AID551096 | Antibacterial activity against Klebsiella pneumoniae by liquid dilution method | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1 | 3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents. |
| AID546961 | Antibacterial activity against Yersinia enterocolitica assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID556562 | Antimicrobial activity against sodA gene-deficient Escherichia coli K-12 3144 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID558539 | Antibacterial activity against bla gene-positive and nitrocefin reaction-positive beta-lactamase harboring Campylobacter coli isolate P1826 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID1767664 | Antibacterial activity against Enterococcus durans BIO 0114 assessed as inhibition of bacterial growth incubated for 24 hrs by microdilution assay | 2021 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 47 | Antimicrobial, modulatory, and antibiofilm activity of tt-farnesol on bacterial and fungal strains of importance to human health. |
| AID1385487 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus isolate 699 by two-fold serial dilution method | 2018 | Journal of natural products, 08-24, Volume: 81, Issue:8 | Abyssomicin Monomers and Dimers from the Marine-Derived Streptomyces koyangensis SCSIO 5802. |
| AID442412 | Antimicrobial activity against Pseudomonas aeruginosa at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID448251 | Antibacterial activity against Bacillus thuringiensis at 2 mg/ml after 24 hrs by agar diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis and antibacterial activity of some new heterocycles incorporating phthalazine. |
| AID548036 | Antimicrobial activity against Escherichia coli DH10B by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID648408 | Antibacterial activity against Pseudomonas aeruginosa ATTC 27853 after 16 to 18 hrs by serial dilution method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Facile synthesis, characterization and pharmacological activities of 3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles and 5,6-dihydro-3,6-disubstituted-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles. |
| AID287234 | Antimicrobial activity against Staphylococcus aureus IFO 3060 at 100 ug/disc after 24 hrs | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles. |
| AID425592 | Antibacterial activity against gentamicin-treated internalized Escherichia coli isolate HM605 in mouse J774A1 cells isolated from colonic mucosal biopsies of patient with Crohn's disease assessed as intracellular killing of bacteria at 0.1 to 100 ug/ml af | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID530522 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype III isolate 8607-03 expressing pbp2x Q557E mutant and harboring plasmid expressing wild-type pbp2x by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID590283 | Antibacterial activity against Staphylococcus aureus ATCC 6538p after 24 hrs by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase. |
| AID1322102 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 254992 after 24 hrs by broth microdilution assay | 2016 | Bioorganic & medicinal chemistry, 11-01, Volume: 24, Issue:21 | Synthesis, characterization, and evaluation of (E)-methyl 2-((2-oxonaphthalen-1(2H)-ylidene)methylamino)acetate as a biological agent and an anion sensor. |
| AID574170 | Antibacterial activity against Escherichia coli MG1655 grown as biofilms harboring plasmid pBR322 carrying blaTEM-1 and tetA(C) genes after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. |
| AID1385490 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 by two-fold serial dilution method | 2018 | Journal of natural products, 08-24, Volume: 81, Issue:8 | Abyssomicin Monomers and Dimers from the Marine-Derived Streptomyces koyangensis SCSIO 5802. |
| AID441922 | Antibacterial activity against Escherichia coli B/r after 24 hrs by NCCLS method | 2009 | Journal of medicinal chemistry, Nov-12, Volume: 52, Issue:21 | Coordination chemistry based approach to lipophilic inhibitors of 1-deoxy-D-xylulose-5-phosphate reductoisomerase. |
| AID564894 | Antibacterial activity against wild-type Escherichia coli AG100 harboring marR mutant gene at 37 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID582894 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87K mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID654568 | Antibacterial activity against Pseudomonas fluorescens after 18 hrs by broth microdilution method | 2012 | Journal of natural products, Feb-24, Volume: 75, Issue:2 | Asperolides A-C, tetranorlabdane diterpenoids from the marine alga-derived endophytic fungus Aspergillus wentii EN-48. |
| AID559350 | Antimicrobial activity against Salmonella spp. harboring shv-like gene assessed as resistant isolates by disk diffusion method | 2009 | Antimicrobial agents and chemotherapy, Jun, Volume: 53, Issue:6 | Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique. |
| AID508292 | Antimicrobial activity against penicillin-resistant Enterococcus faecium D63r by microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Interaction of ceftobiprole with the low-affinity PBP 5 of Enterococcus faecium. |
| AID1493671 | Antimicrobial activity against Bacillus subtilis RCMB 010063 after overnight incubation by macro-tube dilution technique | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Quinoline derivatives bearing pyrazole moiety: Synthesis and biological evaluation as possible antibacterial and antifungal agents. |
| AID534391 | Antibacterial activity against Escherichia coli JM109 by microdilution method | 2008 | Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11 | KHM-1, a novel plasmid-mediated metallo-beta-lactamase from a Citrobacter freundii clinical isolate. |
| AID1616520 | Antibacterial activity against Staphylococcus aureus after 24 hrs by broth microdilution method | 2019 | Journal of natural products, 10-25, Volume: 82, Issue:10 | Highly Oxygenated Triterpenoids and Rare Tetraterpenoids from |
| AID528534 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B503 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID523270 | Permeability across Escherichia coli HN1157/pHSG576oxa7 assessed as permeability coefficient in presence of proton uncoupler carbonyl cyanide meta-chlorophenylhydrazone | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Kinetic parameters of efflux of penicillins by the multidrug efflux transporter AcrAB-TolC of Escherichia coli. |
| AID324210 | Antibacterial activity against Escherichia coli K12 containing PhoU mutant assessed as cell count in log phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1309068 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 16 to 20 hrs by agar dilution method | 2016 | Bioorganic & medicinal chemistry, 08-15, Volume: 24, Issue:16 | Novel benzimidazol-2-ylidene carbene precursors and their silver(I) complexes: Potential antimicrobial agents. |
| AID255551 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853)at concentration 64.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID561727 | Antibacterial activity against Enterococcus faecium assessed as susceptible isolates by CLSI broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. |
| AID577392 | Antimicrobial activity against Escherichia coli O157:H7 185 encoding stx gene cocultured with Stx-phage susceptible Escherichia coli isolate CMUC-172 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID352579 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 at 10 ug after 18 hrs by agar-well diffusion method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Synthesis of some new 1,2,4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities. |
| AID531316 | Ratio of Kcat to Km for Pseudomonas aeruginosa beta-lactamase VIM-2 by spectrophotometry | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family. |
| AID567458 | Antimicrobial activity against Salmonella enterica serovar Typhi isolate 080048Ty by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Plasmid-mediated resistance to cephalosporins in Salmonella enterica serovar Typhi. |
| AID285193 | Antimicrobial activity against Escherichia coli M044 mutant with AG100 lon4::IS186 marR::IS genotype | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Increased genome instability in Escherichia coli lon mutants: relation to emergence of multiple-antibiotic-resistant (Mar) mutants caused by insertion sequence elements and large tandem genomic amplifications. |
| AID529595 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-12 assessed as bacterial density at 2048 ug/ml after 18 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID568826 | Antimicrobial activity against Bacillus pumilus ATCC 14884 at 25 ug/ml by agar diffusion method | 2011 | European journal of medicinal chemistry, Feb, Volume: 46, Issue:2 | Synthesis of 4H-chromene, coumarin, 12H-chromeno[2,3-d]pyrimidine derivatives and some of their antimicrobial and cytotoxicity activities. |
| AID1486829 | Antimicrobial activity against Escherichia coli MTCC 443 incubated for overnight by broth micro dilution method | 2017 | Bioorganic & medicinal chemistry, 08-01, Volume: 25, Issue:15 | 1,2,4-Triazole and 1,3,4-oxadiazole analogues: Synthesis, MO studies, in silico molecular docking studies, antimalarial as DHFR inhibitor and antimicrobial activities. |
| AID555242 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 52 by Etest method of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID777337 | Antibacterial activity against Escherichia coli ATCC 9637 assessed as growth inhibition after 24 hrs by microbroth dilution method | 2013 | ACS medicinal chemistry letters, Oct-10, Volume: 4, Issue:10 | Identification of 1-[4-Benzyloxyphenyl)-but-3-enyl]-1H-azoles as New Class of Antitubercular and Antimicrobial Agents. |
| AID415325 | Antibacterial activity against multidrug-resistant Staphylococcus aureus 3SP/R33 after 18 hrs by broth microdilution method | 2009 | Bioorganic & medicinal chemistry, Apr-15, Volume: 17, Issue:8 | Design, synthesis, antimicrobial activity and molecular modeling studies of novel benzofuroxan derivatives against Staphylococcus aureus. |
| AID463406 | Antimicrobial activity against Salmonella Typhimurium at 1000 ug after 24 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines. |
| AID536632 | Antimicrobial activity against Staphylococcus aureus NCTC 7447 at 5 mg/ml after 24 hrs by agar well diffusion assay | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis of new pyrrolo[2,3-d]pyrimidine derivatives as antibacterial and antifungal agents. |
| AID1462720 | Antimicrobial activity against Staphylococcus aureus MTCC 96 | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20 | Benzothiazole analogues: Synthesis, characterization, MO calculations with PM6 and DFT, in silico studies and in vitro antimalarial as DHFR inhibitors and antimicrobial activities. |
| AID535646 | Antimicrobial activity against Group B Streptococcus serotype III NEM 316 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID378241 | Antimicrobial activity against Sarcina lutea after 48 hrs by paper disk assay | 2000 | Journal of natural products, Nov, Volume: 63, Issue:11 | Metabolites of Colletotrichum gloeosporioides, an endophytic fungus in Artemisia mongolica. |
| AID535632 | Antimicrobial activity against Group B streptococcus R8 harboring T77I, S353F and A514V in PBP 2X; V80A and G613R in PBP 2B; and L45P, N163K, N723S and G527V in PBP 1A by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | Genetic heterogeneity in pbp genes among clinically isolated group B Streptococci with reduced penicillin susceptibility. |
| AID198327 | In vitro testing for minimum inhibitory concentration against Salmonella Typhimurium SL 1102 | 1987 | Journal of medicinal chemistry, Dec, Volume: 30, Issue:12 | Design and synthesis of peptide derivatives of a 3-deoxy-D-manno-2-octulosonic acid (KDO) analogue as novel antibacterial agents acting upon lipopolysaccharide biosynthesis. |
| AID529580 | Ratio of Kcat to Km for Caulobacter crescentus beta-Lactamase CAU-1 | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora. |
| AID1139536 | Antibacterial activity against Escherichia coli DH5alpha by CLSI broth microdilution method | 2014 | Journal of medicinal chemistry, May-08, Volume: 57, Issue:9 | Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. |
| AID324284 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoB mutant assessed as cell count in log phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1471042 | Growth inhibition of Bacillus subtilis NCIM 2162 at 30 ug/ml measured after 12 hrs relative to control | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID529594 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-10 assessed as bacterial density at 2048 ug/ml after 18 hrs relative to control | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID548026 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237H mutant by agar dilution method in presence of beta-lactamase inhibitor Sulbactam | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID678542 | Antibacterial activity against Enterococcus faecalis ATCC 51299 | 2012 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 22, Issue:18 | Design, solvent free synthesis, and antimicrobial evaluation of 1,4 dihydropyridines. |
| AID585432 | Antimicrobial activity against oqxAB positive Escherichia coli DH5[alpha] harboring pMD18-T::oqxAB by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1695825 | Antibacterial activity against Staphylococcus aureus RCMB-010010 assessed as diameter of inhibition zone at 5 mg/ml by diffusion technique | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID540213 | Half life in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID278545 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium animalis ATCC 27536 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1604667 | Antibacterial activity against methicillin-resistant Staphylococcus aureus R3708 by visual method | |||
| AID1204966 | Antimicrobial activity against Bacillus subtilis ATCC 6633 after 24 hrs by twofold dilution method | 2015 | Journal of natural products, Feb-27, Volume: 78, Issue:2 | Additional sesterterpenes and a nortriterpene saponin from the sponge Clathria gombawuiensis. |
| AID577191 | Antimicrobial activity against Escherichia coli O157:H7 185 cocultured with Stx-phage susceptible Escherichia coli isolate CMUC-170 relative to control | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID520987 | Antimicrobial activity against Acinetobacter baumannii WRAIR after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Novel antimicrobial peptides that exhibit activity against select agents and other drug resistant bacteria. |
| AID563971 | Antibacterial activity against Escherichia coli NF-NDM-1 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. |
| AID1852754 | Antibacterial activity against wild type Escherichia coli ATCC 25922 assessed as bacterial growth inhibition by broth microdilution assay | 2022 | RSC medicinal chemistry, Sep-21, Volume: 13, Issue:9 | Design and evaluation of poly-nitrogenous adjuvants capable of potentiating antibiotics in Gram-negative bacteria. |
| AID278247 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-4 tolC::Kan with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1491079 | Antibacterial activity against Kocuria rhizophila NBRC 12708 after 24 hrs by serial two fold dilution method | 2017 | Journal of natural products, 05-26, Volume: 80, Issue:5 | Manzamine Alkaloids from an Acanthostrongylophora sp. Sponge. |
| AID530500 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype IA isolate 5662-05 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID520722 | Antibacterial activity against Escherichia coli DH10B harboring pOXA-97 in presence of 4 ug/ml clavulanic acid | 2008 | Antimicrobial agents and chemotherapy, May, Volume: 52, Issue:5 | Carbapenem-resistant Acinetobacter baumannii isolates from Tunisia producing the OXA-58-like carbapenem-hydrolyzing oxacillinase OXA-97. |
| AID561443 | Antibacterial activity against Escherichia coli 34943 harboring beta-lactamase CMY-44 gene by Etest method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Reduced susceptibility to cefepime among Escherichia coli clinical isolates producing novel variants of CMY-2 beta-lactamase. |
| AID1774181 | Antibacterial activity against Staphylococcus aureus DSM11822 assessed as growth inhibition by measuring minimal concentration at OD600 by visual inspection with iron-limited media incubated for 24 hrs | 2021 | Journal of medicinal chemistry, 10-28, Volume: 64, Issue:20 | Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens. |
| AID300200 | Antibacterial activity against Staphylococcus epidermidis at 200 mg/mL after 24 hrs by disc diffusion method | 2007 | Bioorganic & medicinal chemistry, Aug-15, Volume: 15, Issue:16 | Identification of antibacterial and antiviral activities of novel fused 1,2,4-triazine esters. |
| AID644176 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID1776892 | Antibacterial activity against Streptococcus pneumoniae ATCC49619 at 5 ug/ml | 2021 | Bioorganic & medicinal chemistry letters, 07-15, Volume: 44 | Design, synthesis and antimicrobial activity of novel 2-aminothiophene containing cyclic and heterocyclic moieties. |
| AID520778 | Antibacterial activity against beta-lactamase KPC-2 producing Escherichia coli isolate E1 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli Isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital. |
| AID1224739 | Antimicrobial activity against Escherichia coli MTCC 443 by broth microdilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Ultrasound-assisted one-pot four-component synthesis of novel 2-amino-3-cyanopyridine derivatives bearing 5-imidazopyrazole scaffold and their biological broadcast. |
| AID530050 | Antimicrobial activity against Staphylococcus aureus 286607-R1 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. |
| AID1685000 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as inhibition of bacterial growth incubated for 16 to 20 hrs by microdilution method | 2021 | ACS medicinal chemistry letters, Jan-14, Volume: 12, Issue:1 | Enhancing Antimicrobial Peptide Potency through Multivalent Presentation on Coiled-Coil Nanofibrils. |
| AID1378892 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as diameter of inhibition zone at 100 uM after 24 hrs by cup diffusion method | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Synthesis, antimicrobial, DNA cleavage and antioxidant activities of tricyclic sultams derived from saccharin. |
| AID1491339 | Antibacterial activity against Escherichia coli ATCC 12435 after 24 hrs by two-fold serial dilution method | 2017 | European journal of medicinal chemistry, Sep-08, Volume: 137 | Synthesis, antimicrobial, antiquorum-sensing and antitumor activities of new benzimidazole analogs. |
| AID1769955 | Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC515992 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID444052 | Hepatic clearance in human | 2010 | Journal of medicinal chemistry, Feb-11, Volume: 53, Issue:3 | Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. |
| AID405086 | Ratio of Kcat to Km of Citrobacter freundii PER2 beta lactamase relative to cephalothin | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Biochemical characterization of PER-2 and genetic environment of blaPER-2. |
| AID582919 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 F61W mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID1228006 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 assessed as complete prevention of visible growth after incubation at 37 degC for 18 to 20 hrs | 2015 | Journal of natural products, Apr-24, Volume: 78, Issue:4 | Antibacterial Biphenanthrenes from the Fibrous Roots of Bletilla striata. |
| AID1769804 | Antimicrobial activity against Staphylococcus aureus Sau 16162 assessed as inhibition of bacterial growth incubated for 16 to 18 hrs by broth micro dilution technique | |||
| AID662992 | Antibacterial activity against Escherichia coli MTCC 443 by macrobroth dilution assay | 2012 | Bioorganic & medicinal chemistry letters, Jun-15, Volume: 22, Issue:12 | An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidines. |
| AID1180298 | Bactericidal activity against Salmonella typhimurium NCIM-3471 after 72 hrs by two fold serial macrodilution technique | 2014 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15 | One pot three components microwave assisted and conventional synthesis of new 3-(4-chloro-2-hydroxyphenyl)-2-(substituted) thiazolidin-4-one as antimicrobial agents. |
| AID365666 | Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 13709 Smith after 24 hrs by twofold serial dilution method | 2008 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 18, Issue:16 | Substituted 3-((Z)-2-(4-nitrophenyl)-2-(1H-tetrazol-5-yl) vinyl)-4H-chromen-4-ones as novel anti-MRSA agents: synthesis, SAR, and in-vitro assessment. |
| AID510170 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID325488 | Antimicrobial activity against vancomycin A-resistant Enterococcus faecalis TX2784 isolate by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Time-kill and synergism studies of ceftobiprole against Enterococcus faecalis, including beta-lactamase-producing and vancomycin-resistant isolates. |
| AID1104320 | Antibacterial activity against Escherichia coli ATCC 35210 at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID543065 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ST398 | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Identification of a novel trimethoprim resistance gene, dfrK, in a methicillin-resistant Staphylococcus aureus ST398 strain and its physical linkage to the tetracycline resistance gene tet(L). |
| AID585834 | Antimicrobial activity against ampD, ampDh2, ampDh3 and ampG deficient Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method in presence of 120 uM carbonyl cyanide m-chlorophenyl-hydrazone | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID447439 | Antibacterial activity against Staphylococcus aureus ATCC 6538P at 100 ug/ml after 24 hrs by agar cup plate method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and antibacterial activity of 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-pyrazol-4-yl]-5-(substituted-phenyl)-[1,3,4]oxadiazoles. |
| AID1412922 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 by microdilution method | 2018 | MedChemComm, May-01, Volume: 9, Issue:5 | Design, synthesis and antimicrobial activity of usnic acid derivatives. |
| AID536631 | Antimicrobial activity against Escherichia coli NCTC 10416 at 5 mg/ml after 24 hrs by agar well diffusion assay | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis of new pyrrolo[2,3-d]pyrimidine derivatives as antibacterial and antifungal agents. |
| AID528535 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae B513 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID1695926 | Antibacterial activity against Escherichia coli ATCC 25922 incubated for 24 hrs by broth dilution method | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Comprehensive review on the anti-bacterial activity of 1,2,3-triazole hybrids. |
| AID278255 | Antimicrobial activity against Salmonella enterica serovar Typhimurium CS3 tolC::Kan with GyrA S83F, D87N, parC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID555472 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 128 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID546952 | Antibacterial activity against Shigella flexneri assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID623617 | Antibacterial activity against 10'8 CFU/mL Pseudomonas aeruginosa MTCC 1688 by broth microdilution method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | 1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study. |
| AID723723 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID1194194 | Antimicrobial activity against Fusarium oxysporum f. sp. cubense after 48 hrs by two fold serial microdilution method | 2015 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 25, Issue:8 | Studies on antimicrobial effects of four ligands and their transition metal complexes with 8-mercaptoquinoline and pyridine terminal groups. |
| AID644175 | Antibacterial activity against Listeria monocytogenes NCTC 7973 treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID585866 | Antimicrobial activity against Pseudomonas aeruginosa isolate 13 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1918123 | Antibacterial activity against Escherichia coli harboring delta tolC efflux defective mutant assessed as inhibition of bacterial growth incubated for 16 hrs in presence of 6 ug/ml PMBN by microplate reader analysis (Rvb = >40 microM) | 2022 | Journal of medicinal chemistry, 11-10, Volume: 65, Issue:21 | Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA. |
| AID530504 | Antimicrobial activity against group B Streptococcus sp. 'group B' serotype IB isolate 5436-03 by broth dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. |
| AID558806 | Antimicrobial activity against extended spectrum beta-lactamase-expressing Klebsiella pneumoniae assessed as percent susceptible isolates by CLSI method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Emergence of high levels of extended-spectrum-beta-lactamase-producing gram-negative bacilli in the Asia-Pacific region: data from the Study for Monitoring Antimicrobial Resistance Trends (SMART) program, 2007. |
| AID368423 | Antimicrobial activity against Escherichia coli KAM32 pSTVdeltaqepA containing disrupted qepA gene by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. |
| AID546937 | Antibacterial activity against Salmonella enterica serovar Choleraesuis assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID548001 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237N mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID548012 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237S mutant by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID456074 | Antibacterial activity against Bacillus cereus clinical isolate after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID548946 | Antimicrobial activity against Bacillus cereus ATCC 13061 after18 to 20 hrs by broth dilution method | 2010 | European journal of medicinal chemistry, Dec, Volume: 45, Issue:12 | Synthesis and antimicrobial evaluation of some fused heterocyclic [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives. |
| AID324214 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 assessed as cell count in log phase at 100 ug/ml after 1 day | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID1501235 | Antibacterial activity against Staphylococcus aureus ATCC 6538 measured after overnight incubation | 2017 | Journal of natural products, 09-22, Volume: 80, Issue:9 | Thermoactinoamide A, an Antibiotic Lipophilic Cyclopeptide from the Icelandic Thermophilic Bacterium Thermoactinomyces vulgaris. |
| AID285338 | Antimicrobial activity against streptomycin-resistant Escherichia coli J53 transconjugant with qnrA1 producing urinary specimen isolate 13.52 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First report of plasmid-mediated qnrA1 in a ciprofloxacin-resistant Escherichia coli strain in Latin America. |
| AID255553 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 8.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID520988 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Novel antimicrobial peptides that exhibit activity against select agents and other drug resistant bacteria. |
| AID425400 | Antibacterial activity against Escherichia coli isolate HM605 isolated from colonic mucosal biopsies of patient with Crohn's disease after 24 hrs by Etest antibiotic concentration gradient method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID1193889 | Antimicrobial activity against Staphylococcus aureus MTCC 3160 assessed as zone of inhibition at 5 mg/ml after 24 hrs by agar well diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Rapid 'one-pot' synthesis of a novel benzimidazole-5-carboxylate and its hydrazone derivatives as potential anti-inflammatory and antimicrobial agents. |
| AID369633 | Antimicrobial activity against beta-lactamase positive amoxicillin/clavulanate-resistant Haemophilus influenzae by E-test | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | Can the Etest correctly determine the MICs of beta-lactam and cephalosporin antibiotics for beta-lactamase-negative ampicillin-resistant Haemophilus influenzae? |
| AID456085 | Antibacterial activity against Proteus mirabilis after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID1225329 | Antimicrobial activity against Bacillus subtilis incubated for 24 hrs | 2015 | Journal of natural products, Mar-27, Volume: 78, Issue:3 | Alkaloidal metabolites from a marine-derived Aspergillus sp. fungus. |
| AID555477 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 243 by Etest method in presence of cloxacillin and efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID382688 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 at 572.4 uM by disc-diffusion method | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives. |
| AID478777 | Antibacterial activity against Bacillus cereus ATCC 7064 after 18 hrs by broth microdilution assay | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5 | Synthesis, spectroscopic and biological studies on the new symmetric Schiff base derived from 2,6-diformyl-4-methylphenol with N-aminopyrimidine. |
| AID1388195 | Antibacterial activity against Staphylococcus aureus MTCC 3381 at 100 ug/ml incubated for 12 hrs by agar disc diffusion assay | 2017 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 27, Issue:18 | Synthesis, antimicrobial activity, structure-activity relationship and cytotoxic studies of a new series of functionalized (Z)-3-(2-oxo-2-substituted ethylidene)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-ones. |
| AID1056535 | Antibacterial activity against methicillin-resistant Staphylococcus epidermidis clinical isolate shhs-E1 by broth microdilution method | 2013 | Journal of natural products, Dec-27, Volume: 76, Issue:12 | Cytotoxic and antibacterial marfuraquinocins from the deep South China Sea-derived Streptomyces niveus SCSIO 3406. |
| AID1139543 | Antibacterial activity against Escherichia coli DH5alpha expressing beta-lactamase VIM-2 by CLSI broth microdilution method | 2014 | Journal of medicinal chemistry, May-08, Volume: 57, Issue:9 | Siderophore receptor-mediated uptake of lactivicin analogues in gram-negative bacteria. |
| AID585015 | Antibacterial activity against Staphylococcus aureus ATCC 29213 | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Inhibition of bacterial multidrug resistance by celecoxib, a cyclooxygenase-2 inhibitor. |
| AID294965 | Antibacterial activity against Escherichia coli ATCC 23556 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID264078 | Antibacterial activity against Bacillus subtilis ATCC 6633 | 2006 | Bioorganic & medicinal chemistry letters, May-01, Volume: 16, Issue:9 | Studies on synthesis and evaluation of quantitative structure-activity relationship of 10-methyl-6-oxo-5-arylazo-6,7-dihydro-5H-[1,3]azaphospholo[1,5-d][1,4]benzodiazepin-2-phospha-3-ethoxycarbonyl-1-phosphorus dichlorides. |
| AID334239 | Antimicrobial activity against Cladosporium cladosporioides IMI 299104 after 10 days by microdilution technique | 2002 | Journal of natural products, Apr, Volume: 65, Issue:4 | Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline. |
| AID555251 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 65 by Etest method in presence of efflux pump inhibitor CCCP | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID558338 | Antibacterial activity against bla gene-positive and nitrocefin reaction-positive beta-lactamase harboring Campylobacter jejuni isolate P1730 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID1303881 | Antibacterial activity against multidrug resistant Enterococcus faecium NCTC 7171 (ATCC 19434) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID584298 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus fleurettii SFMP08 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID324287 | Antibacterial activity against Escherichia coli K12 containing deletion deltaphoR mutant assessed as cell count in stationary phase at 100 ug/ml after 5 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID607164 | Antimicrobial activity against Staphylococcus aureus after 24 hrs by disc diffusion method | 2011 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 21, Issue:14 | Exploration of antimicrobial and antioxidant potential of newly synthesized 2,3-disubstituted quinazoline-4(3H)-ones. |
| AID584325 | Antibacterial activity against wild type Escherichia coli BW25113 | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | Interplay between drug efflux and antioxidants in Escherichia coli resistance to antibiotics. |
| AID419335 | Antibacterial activity against Escherichia coli ATCC 25922 at 10 ug/ml after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis and evaluation of some new benzimidazole derivatives as potential antimicrobial agents. |
| AID360842 | Antibacterial activity against Streptococcus agalactiae ATCC 13813 at 10 ug/disk after overnight incubation by agar diffusion test | 2002 | Journal of natural products, Jul, Volume: 65, Issue:7 | Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. |
| AID533368 | Antimicrobial activity against Bacteroides uniformis assessed as resistant isolates by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Dec, Volume: 52, Issue:12 | In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group. |
| AID555454 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 52 by Etest method in presence of cloxacillin and efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1551783 | Antibacterial activity against Staphylococcus aureus | 2019 | European journal of medicinal chemistry, Jul-01, Volume: 173 | Antibacterial activity study of 1,2,4-triazole derivatives. |
| AID1908115 | Antibacterial activity against Staphylococcus aureus ATCC 29213 assessed as inhibition of bacterial growth incubated for 20 to 24 hrs by broth micro dilution method | 2022 | European journal of medicinal chemistry, Jun-05, Volume: 236 | Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. |
| AID496590 | Antimicrobial activity against Klebsiella pneumoniae 1534 harboring beta lactamase KPC-2 by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Inhibitor resistance in the KPC-2 beta-lactamase, a preeminent property of this class A beta-lactamase. |
| AID510161 | Antimicrobial activity against Proteus mirabilis ATCC 7002 by spectrophotometry | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. |
| AID723718 | Bactericidal activity against Staphylococcus aureus ATCC 6538 after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID1352296 | Antibacterial activity against Staphylococcus aureus ATCC 25923 at 30 ug/disk | 2018 | European journal of medicinal chemistry, Feb-10, Volume: 145 | Bysspectin A, an unusual octaketide dimer and the precursor derivatives from the endophytic fungus Byssochlamys spectabilis IMM0002 and their biological activities. |
| AID383176 | Antimicrobial activity against Salmonella Typhimurium ATCC 14028 | 2008 | Journal of natural products, Apr, Volume: 71, Issue:4 | Sesterterpenoids from the sponge Sarcotragus sp. |
| AID725078 | Antimicrobial activity against Salmonella typhimurium after 12 to 18 hrs by micro-well dilution method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Synthesis and antibacterial and antifungal evaluation of some chalcone based sulfones and bisulfones. |
| AID287372 | Antibacterial activity against Staphylococcus aureus after 72 hrs by disk diffusion method | 2007 | European journal of medicinal chemistry, Feb, Volume: 42, Issue:2 | Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. |
| AID678543 | Antibacterial activity against Bacillus subtilis ATCC 9372 | 2012 | Bioorganic & medicinal chemistry letters, 09-15, Volume: 22, Issue:18 | Design, solvent free synthesis, and antimicrobial evaluation of 1,4 dihydropyridines. |
| AID429368 | Antibacterial activity against Salmonella Typhimurium after 24 hrs by liquid dilution method | 2009 | European journal of medicinal chemistry, Aug, Volume: 44, Issue:8 | Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents. |
| AID442414 | Antimicrobial activity against Salmonella Typhimurium at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1286507 | Antibacterial activity against methicillin-resistant Staphylococcus aureus after 20 to 24 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID1535447 | Anti-biofilm activity against Pseudoalteromonas ulvae TC14 assessed as inhibition of bacterial adhesion incubated for 15 hrs at 20 degC by Syto 61 dye based fluorescence assay | 2019 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 29, Issue:4 | Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds? |
| AID657434 | Antibacterial activity against penicillin-susceptible Streptococcus pneumoniae after 16 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9 | Preparation, antibacterial evaluation and preliminary structure-activity relationship (SAR) study of benzothiazol- and benzoxazol-2-amine derivatives. |
| AID509630 | Antimicrobial activity against Staphylococcus aureus RN4220 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain. |
| AID529305 | Antimicrobial activity against Acinetobacter genospecies 3 isolate Ac057 expressing beta-lactamase Oxa-58 by broth microdilution method in presence of beta-lactamase inhibitor Sulbactam | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Characterization of the carbapenem-hydrolyzing oxacillinase oxa-58 in an Acinetobacter genospecies 3 clinical isolate. |
| AID523888 | Antimicrobial activity against Acinetobacter baumannii 6AB11 harboring ISAba1-blaOXA-66 gene by Etest | 2010 | Antimicrobial agents and chemotherapy, May, Volume: 54, Issue:5 | Genetic basis of multidrug resistance in Acinetobacter clinical isolates in Taiwan. |
| AID324299 | Antibacterial activity against Escherichia coli K12 containing deletion deltahipA mutant assessed as cell count in stationary phase at 100 ug/ml after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID203426 | In vitro inhibitory activity against Staphylococci EryRi (65);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID535359 | Antimicrobial activity against Streptococcus pyogenes clinical isolates assessed as resistant isolates by broth dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Antimicrobial resistance among respiratory pathogens in Spain: latest data and changes over 11 years (1996-1997 to 2006-2007). |
| AID584474 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN04 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID514133 | Antibacterial activity against Pseudomonas aeruginosa PAO1 assessed as growth inhibition at 1 mg/ml after 16 to 20 hrs in presence of 0.2 mM L-histidine | 2010 | Bioorganic & medicinal chemistry, Jul-15, Volume: 18, Issue:14 | Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays. |
| AID1896862 | Resistance development in Escherichia coli ATCC25922 assessed as fold increase in resistance after 15 days serial passage upto 256 ug/ml | |||
| AID731202 | Antibacterial activity against Salmonella typhi MTCC 98 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles. |
| AID556563 | Antimicrobial activity against sodB gene-deficient Escherichia coli K-12 3145 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Apr, Volume: 53, Issue:4 | Contribution of oxidative damage to antimicrobial lethality. |
| AID1290440 | Antibacterial activity against Clostridium tetani MTCC 449 after 24 to 48 hrs by broth microdilution method | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities. |
| AID447591 | Antibacterial activity against Klebsiella pneumoniae ATCC 11298 after 24 hrs by microtitration method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, characterization and antibacterial activity of 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-pyrazol-4-yl]-5-(substituted-phenyl)-[1,3,4]oxadiazoles. |
| AID1577952 | Antimicrobial activity against Pseudomonas aeruginosa PA4 under iron-sufficient condition by CLSI protocol based broth microdilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | An overview of recent progress in siderophore-antibiotic conjugates. |
| AID1704196 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by CLSI-based broth microdilution method | 2020 | European journal of medicinal chemistry, Nov-15, Volume: 206 | 1,2,3-Triazole-containing hybrids with potential antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA). |
| AID1614667 | Antibacterial activity against Escherichia coli isolate 6/23 infected in wound areas of BALB/c mouse assessed as reduction in colony forming units at 40 mg/kg dosed thrice daily for 4 days starting 6 hrs post infection and measured on day 5 | 2019 | Journal of medicinal chemistry, 02-28, Volume: 62, Issue:4 | Deciphering the Role of Intramolecular Networking in Cholic Acid-Peptide Conjugates on the Lipopolysaccharide Surface in Combating Gram-Negative Bacterial Infections. |
| AID577205 | Antimicrobial activity against Escherichia coli O157:H7 PT-32 in logarithmic phase encoding Stx-1 and Stx-2 gene by broth macrodilution assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Different classes of antibiotics differentially influence shiga toxin production. |
| AID1424743 | Antimicrobial activity against Bacillus cereus UW 85 after 24 hrs by two-fold serial dilution method | 2018 | European journal of medicinal chemistry, May-25, Volume: 152 | New pyrazolopyridine analogs: Synthesis, antimicrobial, antiquorum-sensing and antitumor screening. |
| AID1668053 | Inhibition of DHPS in Bacillus subtilis assessed as antibacterial activity by measuring inhibition zone at 5 mg/mL incubated for 24 hrs by disk diffusion method | 2020 | Bioorganic & medicinal chemistry, 05-01, Volume: 28, Issue:9 | New acrylamide-sulfisoxazole conjugates as dihydropteroate synthase inhibitors. |
| AID325447 | Antibacterial activity against Staphylococcus aureus N315 after 14 to 16 hrs by broth dilution method | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | Polyamine effects on antibiotic susceptibility in bacteria. |
| AID1328339 | Antibacterial activity against Yersinia enterocolitica ATCC 23715 assessed as zone of inhibition at 100 ug/disk measured after 24 hrs by agar disk-diffusion method | 2016 | Journal of natural products, 09-23, Volume: 79, Issue:9 | Halogenated Sesquiterpenoids from the Red Alga Laurencia tristicha Collected in Taiwan. |
| AID1486830 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 1688 incubated for overnight by broth micro dilution method | 2017 | Bioorganic & medicinal chemistry, 08-01, Volume: 25, Issue:15 | 1,2,4-Triazole and 1,3,4-oxadiazole analogues: Synthesis, MO studies, in silico molecular docking studies, antimalarial as DHFR inhibitor and antimicrobial activities. |
| AID477777 | Antimicrobial activity Bacillus thuringiensis at 2 mg/mL after 24 hrs by agar diffusion technique | 2010 | European journal of medicinal chemistry, Apr, Volume: 45, Issue:4 | Synthesis and study of some new 1,3-isoindoledione derivatives as potential antibacterial agents. |
| AID584484 | Antibacterial activity against mecA-negative Staphylococcus vitulinus SVMN14 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID478498 | Antifungal activity against Alternaria solani at 2 mg/ml after 7 days by agar diffusion method | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5 | Synthesis and antimicrobial of new anthraquinone derivatives incorporating pyrazole moiety. |
| AID1647640 | Antibacterial activity against Salmonella enterica ATCC 14028 assessed as reduction in microbial growth | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Isocadiolides A-H: Polybrominated Aromatics from a |
| AID528523 | Antimicrobial activity against penicillin-resistant Streptococcus agalactiae ATCC 12403 by agar dilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | First molecular characterization of group B streptococci with reduced penicillin susceptibility. |
| AID544583 | Antimicrobial activity against Escherichia coli DH5[alpha] by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Pyrosequencing using the single-nucleotide polymorphism protocol for rapid determination of TEM- and SHV-type extended-spectrum beta-lactamases in clinical isolates and identification of the novel beta-lactamase genes blaSHV-48, blaSHV-105, and blaTEM-155 |
| AID1286501 | Ratio of MBC for methicillin-sensitive Staphylococcus aureus ATCC 25923 to MIC90 for methicillin-sensitive Staphylococcus aureus ATCC 25923 | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID386623 | Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells at 100 uM by confocal microscopy | 2008 | Journal of medicinal chemistry, Oct-09, Volume: 51, Issue:19 | Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. |
| AID1132047 | Antibacterial activity against Staphylococcus aureus 1517 | 1978 | Journal of medicinal chemistry, Jan, Volume: 21, Issue:1 | Thiazolinone analogues of indolmycin with antiviral and antibacterial activity. |
| AID1535457 | Effect on cell viability of Pseudoalteromonas lipolytica TC8 at 5 uM measured after 6 hrs by resazurin dye based fluorescence assay | 2019 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 29, Issue:4 | Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds? |
| AID582901 | Antimicrobial activity against Escherichia coli XL1-Blue VIM-2 W87P mutant beta-lactamase by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID530286 | Antimicrobial activity against PR-39-resistant Salmonella enterica serovar Typhimurium LT2 DA10899 harboring Q179Stop mutant gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2. |
| AID447069 | Antibacterial activity against Listeria monocytogenes ATCC 15313 at 10 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID422494 | Antimicrobial activity against Escherichia coli BL21 (DE3) by E-test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens. |
| AID573362 | Antibacterial activity against ceftazidime-nonsusceptible Klebsiella pneumoniae assessed as susceptible isolates by CLSI M7-A7 broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States. |
| AID633493 | Antifungal activity against Trichophyton rubrum IFO 9185 after 48 to 72 hrs by two fold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23 | Synthesis and antimicrobial activity of brominated resorcinol dimers. |
| AID1617681 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 by CLSI based two-fold serial dilution method | |||
| AID555265 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 109 by Etest method in presence of efflux pump inhibitor PAN | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID427674 | Antimicrobial activity against Bacillus subtilis ATCC 11229 after 24 hrs by dilution susceptibility assay | 2009 | Bioorganic & medicinal chemistry, Jul-01, Volume: 17, Issue:13 | Synthesis and antimicrobial activity of 4-hydroxy-4-(pyridyl)alk-3-en-2-ones. |
| AID382716 | Antimicrobial activity against Streptococcus agalactiae at 572.4 uM by disc-diffusion method | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives. |
| AID447066 | Antibacterial activity against Micrococcus luteus La 2971 at 10 ug after 24 hrs by agar disk diffusion assay | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. |
| AID278537 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium breve ATCC 15700 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID582925 | Ratio of Kcat to Km for Escherichia coli BL21(DE3) VIM-2 W87F mutant beta-lactamase by spectrophotometer | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. |
| AID585438 | Antimicrobial activity against ampG deficient Pseudomonas aeruginosa PAO1 after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID519110 | Antibacterial activity against Proteus mirabilis M 55 mutant after 18 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | Reduced Susceptibility of Proteus mirabilis to triclosan. |
| AID425605 | Cytotoxicity against mouse J774A1 cells assessed as macrophage number at 3.2 ug/ml after 3 hrs by total cell protein assay | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. |
| AID1596670 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID1778092 | Antibacterial activity against Bacillus subtilis 168 assessed as inhibition of bacterial growth incubated for 18 hrs by broth microdilution method | |||
| AID655696 | Antibacterial activity against Salmonella typhimurium ATCC 23564 at 20 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID558535 | Antibacterial activity against bla gene-negative and nitrocefin reaction-positive beta-lactamase harboring Campylobacter jejuni isolate P843 by NCCLS agar doubling dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni. |
| AID1852770 | Drug uptake in wild type Escherichia coli ATCC 25922 assessed as drug accumulation across outer membrane | 2022 | RSC medicinal chemistry, Sep-21, Volume: 13, Issue:9 | Design and evaluation of poly-nitrogenous adjuvants capable of potentiating antibiotics in Gram-negative bacteria. |
| AID546947 | Antibacterial activity against Salmonella enterica serovar Heidelberg assessed as percent resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. |
| AID735217 | Antimicrobial activity against Escherichia coli MTCC 443 assessed as growth inhibition measured after overnight incubation by broth dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | New 2-benzylsulfanyl-nicotinic acid based 1,3,4-oxadiazoles: their synthesis and biological evaluation. |
| AID419329 | Antibacterial activity against Bacillus subtilis MTCC 121 at 10 ug/ml after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis and evaluation of some new benzimidazole derivatives as potential antimicrobial agents. |
| AID1721975 | Antibacterial activity against Xanthomonas campestris by microdilution method | 2020 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 30, Issue:17 | New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. |
| AID161934 | In vitro inhibitory activity against Pneumococci PenR (65);ND=not determined | 1998 | Journal of medicinal chemistry, Oct-08, Volume: 41, Issue:21 | Synthesis and antibacterial activity of ketolides (6-O-methyl-3-oxoerythromycin derivatives): a new class of antibacterials highly potent against macrolide-resistant and -susceptible respiratory pathogens. |
| AID736472 | Antibacterial activity against Pseudomonas aeruginosa RCMB 010043 assessed as growth inhibition after 24 hrs by twofold serial dilution method | 2013 | European journal of medicinal chemistry, Apr, Volume: 62 | Synthesis of some new 2-(3-pyridyl)-4,5-disubstituted thiazoles as potent antimicrobial agents. |
| AID1105398 | Antibacterial activity against Pseudomonas aeruginosa MTCC 2581 assessed as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID1060496 | Antibacterial activity against Escherichia coli MTCC 739 by agar streak dilution method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Access to a new class of biologically active quinoline based 1,2,4-triazoles. |
| AID1412919 | Antibacterial activity against Staphylococcus aureus ATCC 6538 by microdilution method | 2018 | MedChemComm, May-01, Volume: 9, Issue:5 | Design, synthesis and antimicrobial activity of usnic acid derivatives. |
| AID425864 | Antimicrobial activity against Carnobacterium divergens CIP101029 at 3 McFarland inoculum size by E-test | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens. |
| AID775561 | Antimicrobial activity against Staphylococcus aureus ATCC 29213 after 24 hrs by broth microdilution method | 2013 | Bioorganic & medicinal chemistry, Nov-01, Volume: 21, Issue:21 | New derivatives of salicylamides: Preparation and antimicrobial activity against various bacterial species. |
| AID278241 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-3 gyrA+ with ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID529744 | Antibacterial activity against Beta-lactamase positive Haemophilus influenzae harboring fst1 mutant gene assessed as susceptible isolates after 20 to 24 hrs by Etest method | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. |
| AID1471034 | Growth inhibition of Escherichia coli NCIM 2576 at 10 ug/ml measured after 8 hrs relative to control | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID1767678 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as inhibition of bacterial growth incubated for 24 hrs by microdilution assay | 2021 | Bioorganic & medicinal chemistry letters, 09-01, Volume: 47 | Antimicrobial, modulatory, and antibiofilm activity of tt-farnesol on bacterial and fungal strains of importance to human health. |
| AID590286 | Antifungal activity against Candida albicans ATCC 10231 at 100 ug/ml after 2 weeks | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase. |
| AID622558 | Antimicrobial activity against Clostridium tetani MTCC 449 for 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry letters, Oct-15, Volume: 21, Issue:20 | Microwave assisted synthesis and antimicrobial evaluation of new fused pyran derivatives bearing 2-morpholinoquinoline nucleus. |
| AID360059 | Inhibition of Enterococcus faecium M512 LDtfm transpeptidase activity assessed as tri-aspartate-tri-aspartate multimer containing L-Lys3 to D-Asp-L-Lys3 cross links at 8 ug/ml | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID1303893 | Antibacterial activity against multidrug resistant Klebsiella pneumoniae subsp. pneumoniae NCTC 9633 (ATCC 13883) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID275133 | Antibacterial activity against Escherichia coli IAM1257 | 2007 | Journal of natural products, Jan, Volume: 70, Issue:1 | Antimicrobial arylcoumarins from Asphodelus microcarpus. |
| AID565455 | Antimicrobial activity against Streptococcus intermedius NCTC 11324 planktonic cells assessed as bacterial count at 0.08 ug/ml (Rvb =771.7 +/- 35.14 10'8 CFU/ml) | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | AI-2/LuxS is involved in increased biofilm formation by Streptococcus intermedius in the presence of antibiotics. |
| AID585852 | Antimicrobial activity against Pseudomonas aeruginosa isolate 6 obtained from cystic fibrosis patients after 16 to 20 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | ampG gene of Pseudomonas aeruginosa and its role in β-lactamase expression. |
| AID1337785 | Antifungal activity against Fusarium oxysporum NCIM 1332 by standard agar method | 2017 | European journal of medicinal chemistry, Jan-05, Volume: 125 | Quinolidene-rhodanine conjugates: Facile synthesis and biological evaluation. |
| AID519013 | Ratio of Kcat to Km for Beta-lactamase TEM-10 | 2008 | Antimicrobial agents and chemotherapy, Mar, Volume: 52, Issue:3 | E240V substitution increases catalytic efficiency toward ceftazidime in a new natural TEM-type extended-spectrum beta-lactamase, TEM-149, from Enterobacter aerogenes and Serratia marcescens clinical isolates. |
| AID558012 | Antimicrobial activity in Porphyromonas gingivalis by CLSI agar dilution method in presence of Sulbactam | 2009 | Antimicrobial agents and chemotherapy, May, Volume: 53, Issue:5 | Antianaerobic activity of sulopenem compared to six other agents. |
| AID1535446 | Anti-biofilm activity against Paracoccus sp. 4M6 assessed as bacterial adhesion at 200 uM incubated for 15 hrs at 20 degC by Syto 61 dye based fluorimetric assay relative to control | 2019 | Bioorganic & medicinal chemistry letters, 02-15, Volume: 29, Issue:4 | Parallel synthesis of a bis-triazoles library as psammaplin A analogues: A new wave of antibiofilm compounds? |
| AID1322097 | Antimicrobial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by broth microdilution assay | 2016 | Bioorganic & medicinal chemistry, 11-01, Volume: 24, Issue:21 | Synthesis, characterization, and evaluation of (E)-methyl 2-((2-oxonaphthalen-1(2H)-ylidene)methylamino)acetate as a biological agent and an anion sensor. |
| AID278539 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium infantis ATCC 15697 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1365606 | Antibacterial activity against Escherichia coli MTCC 443 | 2017 | Bioorganic & medicinal chemistry, 11-01, Volume: 25, Issue:21 | Recently reported biological activities of pyrazole compounds. |
| AID1471037 | Growth inhibition of Pseudomonas fluorescens NCIM 2059 at 10 ug/ml measured after 8 hrs relative to control | 2017 | European journal of medicinal chemistry, May-26, Volume: 132 | Synthesis and antimycobacterial screening of new thiazolyl-oxazole derivatives. |
| AID1896842 | Antibacterial activity against Escherichia coli ATCC25922 assessed as prevention of visible growth by broth microdilution method | |||
| AID421842 | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 700788 | 2009 | Journal of natural products, Feb-27, Volume: 72, Issue:2 | Glionitrin A, an antibiotic-antitumor metabolite derived from competitive interaction between abandoned mine microbes. |
| AID1778097 | Antibacterial activity against methicillin resistant Staphylococcus epidermidis assessed as bacterial growth inhibition after 18 hrs by broth microdilution method | |||
| AID442422 | Antimicrobial activity against Salmonella Typhimurium at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID775963 | Antibacterial activity against Enterococcus faecalis ATCC 29212 assessed as growth inhibition at 100 ug/mL after 18 to 24 hrs by microdilution assay | 2013 | European journal of medicinal chemistry, Nov, Volume: 69 | Synthesis, antibacterial and antioxidant activities of new 1-alkyl-4-(1-alkyl-4-oxo-1,4-dihydroquinolin-2-yl)pyridinium bromides. |
| AID1185702 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 after 24 hrs by agar dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | New thiophene-1,2,4-triazole-5(3)-ones: highly bioactive thiosemicarbazides, structures of Schiff bases and triazole-thiols. |
| AID1545445 | Antibacterial activity against Escherichia coli assessed as zone inhibition at 500 ug/ml by cup plate agar diffusion method | 2019 | Bioorganic & medicinal chemistry, 04-01, Volume: 27, Issue:7 | Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances. |
| AID584296 | Antibacterial activity against methicillin-resistant mecA-positive Staphylococcus fleurettii SFMP06 by agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. |
| AID1193886 | Antimicrobial activity against Bacillus subtilis MTCC 441 after 24 hrs by broth dilution method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Rapid 'one-pot' synthesis of a novel benzimidazole-5-carboxylate and its hydrazone derivatives as potential anti-inflammatory and antimicrobial agents. |
| AID1204389 | Antibacterial activity against Escherichia coli assessed as lowest concentration required to reduce growth by 1% after 8 hrs by ELISA plate reader analysis relative to control | 2015 | European journal of medicinal chemistry, Jun-05, Volume: 97 | Benzaldehyde Schiff bases regulation to the metabolism, hemolysis, and virulence genes expression in vitro and their structure-microbicidal activity relationship. |
| AID587245 | Antimicrobial activity against Escherichia coli DSM 682 after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID1224737 | Antimicrobial activity against Bacillus subtilis MTCC 441 by broth microdilution method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Ultrasound-assisted one-pot four-component synthesis of novel 2-amino-3-cyanopyridine derivatives bearing 5-imidazopyrazole scaffold and their biological broadcast. |
| AID340888 | Antimicrobial activity against Escherichia coli JM83 harboring pACYC184-TEM by serial dilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Cytoplasmic-membrane anchoring of a class A beta-lactamase and its capacity in manifesting antibiotic resistance. |
| AID564887 | Antibacterial activity against wild-type Escherichia coli AG100 harboring IS186 insertion in lon3 gene, Tn5 insertion in ycgE gene and plasmid pMPM carrying ompF gene at 26 degC by Etest method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. |
| AID529596 | Antibacterial activity against Escherichia coli TP1 harboring pBR322 carrying TEM-1 assessed as inhibition of bacterial growth at 4096 ug/ml after 18 hrs | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Fitness trade-offs in blaTEM evolution. |
| AID324238 | Antibacterial activity against Escherichia coli K12 PhoU wild type W3110 assessed as cell count in log phase at 100 ug/ml after 10 days | 2007 | Antimicrobial agents and chemotherapy, Jun, Volume: 51, Issue:6 | PhoU is a persistence switch involved in persister formation and tolerance to multiple antibiotics and stresses in Escherichia coli. |
| AID655624 | Antibacterial activity against Pseudomonas aeruginosa ATCC 15499 at 160 uM/ml after 24 hrs by kirby-bauer method | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Design, synthesis, synergistic antimicrobial activity and cytotoxicity of 4-aryl substituted 3,4-dihydropyrimidinones of curcumin. |
| AID590285 | Antibacterial activity against Proteus vulgaris ATCC 3851 after 24 hrs by by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase. |
| AID1399252 | Antimicrobial activity against Bacillus subtilis ATCC 23857 after 18 to 20 hrs by microbroth dilution method | 2018 | Bioorganic & medicinal chemistry letters, 10-01, Volume: 28, Issue:18 | New β-lactam - Tetramic acid hybrids show promising antibacterial activities. |
| AID1286514 | Bactericidal activity against methicillin-resistant Staphylococcus aureus clinical isolate after 24 and 48 hrs | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5 | Robenidine Analogues as Gram-Positive Antibacterial Agents. |
| AID529901 | Antimicrobial activity against Leptospira interrogans serovar Icterohaemorrhagiae isolate 10 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira. |
| AID495342 | Antimicrobial activity against Beta-lactamase-positive, ampicillin-cluvulanate-resistant Haemophilus influenzae with Asp350Asn, Met377Ile, Ala502Val, Asn526Lys substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID495349 | Antimicrobial activity against Beta-lactamase-positive, ampicillin-cluvulanate-resistant Haemophilus influenzae with Asp350Asn, Ala437Ser substitutions in penicillin-binding protein 3 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Antimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance. |
| AID567772 | Antimicrobial activity against Bacillus subtilis ATCC 6638 assessed as >99.9 % reduction in CFU after 18 hrs by broth microdilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and antimicrobial activity of thiosemicarbazides, s-triazoles and their Mannich bases bearing 3-chlorophenyl moiety. |
| AID1647637 | Antibacterial activity against Staphylococcus aureus ATCC 6538P assessed as reduction in microbial growth | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Isocadiolides A-H: Polybrominated Aromatics from a |
| AID562389 | Antimicrobial activity against Enterococcus faecalis clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID496382 | Antibacterial activity against nontypeable beta-lactamase-negative ampicillin-resistant Haemophilus influenzae 4437 | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Efficacy of clarithromycin against experimentally induced pneumonia caused by clarithromycin-resistant Haemophilus influenzae in mice. |
| AID684947 | Antibacterial activity against Escherichia coli ATCC 9637 after 24 hrs by broth microdilution method | 2012 | European journal of medicinal chemistry, Oct, Volume: 56 | Micelles catalyzed chemo- and regio-selective one pot and one step synthesis of 2,3,5,6-tetrakis(alkyl and arylsulfanyl)-1,4-benzoquinones and 2,5-diaminosubstituted-1,4-benzoquinones "In-Water" and their biological evaluation as antibacterial and antifun |
| AID374111 | Antimicrobial activity against azide-resistant aac(6')-Ib-cr deficient Escherichia coli J53 qnrA1 bearing pHS5 transconjugant from Enterobacter cloacae 641 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID405305 | Antibacterial activity against beta-lactamase nonproducing ampicillin susceptible Haemophilus influenzae isolate assessed as percent susceptible isolates by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID278243 | Antimicrobial activity against Salmonella enterica serovar Typhimurium S21-3 tolC::Kan with GyrA S83F, ParC S80I mutation | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials. |
| AID1185703 | Antimicrobial activity against Listeria monocytogenes ATCC 43251 after 24 hrs by agar dilution method | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | New thiophene-1,2,4-triazole-5(3)-ones: highly bioactive thiosemicarbazides, structures of Schiff bases and triazole-thiols. |
| AID1439800 | Antibacterial activity against Escherichia coli MTCC 1652 at 100 ug incubated for 24 hrs under dark condition by agar well diffusion method | 2017 | Bioorganic & medicinal chemistry letters, 04-01, Volume: 27, Issue:7 | Biologically active perspective synthesis of heteroannulated 8-nitroquinolines with green chemistry approach. |
| AID420220 | Antimicrobial activity against multidrug-resistant Staphylococcus aureus H.C. 21036 isolate after 20 hrs by twofold serial dilution technique | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. |
| AID542590 | Antimicrobial activity against plasmid encoded beta-lactamase OXA-58 deficient Acinetobacter radioresistens by CLSI method in presence of beta-lactamase inhibitor Sulbactam | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Codetection of blaOXA-23-like gene (blaOXA-133) and blaOXA-58 in Acinetobacter radioresistens: report from the SENTRY antimicrobial surveillance program. |
| AID255530 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 128.0 uM/ml in dimethylformamide, - = susceptible | 2005 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 15, Issue:19 | Aqua mediated synthesis of substituted 2-amino-4H-chromenes and in vitro study as antibacterial agents. |
| AID1265691 | Antibiofilm activity against Pseudoalteromonas ulvae TC14 assessed as microbial adhesion at 200 uM after 15 hrs by Syto61 based-fluorescence analysis relative to control | 2015 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 25, Issue:24 | Click-based synthesis of bromotyrosine alkaloid analogs as potential anti-biofilm leads for SAR studies. |
| AID1769963 | Antibacterial activity against Pseudomonas aeruginosa ATCC27853 assessed as reduction in microbial growth after 16 to 18 hrs by microbroth dilution method | 2021 | European journal of medicinal chemistry, Nov-15, Volume: 224 | Synthetic cajaninstilbene acid derivatives eradicate methicillin-resistant Staphylococcus aureus persisters and biofilms. |
| AID360074 | Inhibition of Enterococcus faecium M512 PBP5fm transpeptidase activity assessed as tetra -aspartate-tetra -aspartate-tri-aspartate multimer containing D-Ala4 to D-Asp-L-Lys3 cross links at 128 ug/ml by mass spectrometry | 2007 | The Journal of biological chemistry, Oct-19, Volume: 282, Issue:42 | Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem. |
| AID405329 | Antibacterial activity against beta-lactamase nonproducing ampicillin resistant Haemophilus influenzae group IId isolates with acrR mutation by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime. |
| AID595436 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by by twofold serial dilution method | 2011 | Journal of natural products, Apr-25, Volume: 74, Issue:4 | Scalarane sesterterpenes from the sponge Hyatella sp. |
| AID415322 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs by broth microdilution method | 2009 | Bioorganic & medicinal chemistry, Apr-15, Volume: 17, Issue:8 | Design, synthesis, antimicrobial activity and molecular modeling studies of novel benzofuroxan derivatives against Staphylococcus aureus. |
| AID547786 | Antimicrobial activity against Escherichia coli DH10B harboring beta-lactamase KPC-2 T237L mutant by agar dilution method in presence of beta-lactamase inhibitor clavulanic acid | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase. |
| AID632563 | Antibacterial activity against Escherichia coli at 200 ug/mL after 24 hrs by agar cup diffusion method | 2011 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 21, Issue:24 | A new antifungal briarane diterpenoid from the gorgonian Junceella juncea Pallas. |
| AID657432 | Antibacterial activity against methicillin-susceptible Staphylococcus aureus after 16 hrs by broth microdilution method | 2012 | Bioorganic & medicinal chemistry letters, May-01, Volume: 22, Issue:9 | Preparation, antibacterial evaluation and preliminary structure-activity relationship (SAR) study of benzothiazol- and benzoxazol-2-amine derivatives. |
| AID554986 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 21 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID1493684 | Antimicrobial activity against Staphylococcus epidermidis RCMB 010024 assessed as diameter of zone inhibition at 1 mg/ml after 24 hrs by agar well diffusion assay | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Quinoline derivatives bearing pyrazole moiety: Synthesis and biological evaluation as possible antibacterial and antifungal agents. |
| AID300438 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by broth microdilution test | 2007 | Bioorganic & medicinal chemistry, Sep-01, Volume: 15, Issue:17 | 1-Acylthiosemicarbazides, 1,2,4-triazole-5(4H)-thiones, 1,3,4-thiadiazoles and hydrazones containing 5-methyl-2-benzoxazolinones: synthesis, analgesic-anti-inflammatory and antimicrobial activities. |
| AID352616 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus ATCC 431300 by tube dilution method | 2009 | European journal of medicinal chemistry, Mar, Volume: 44, Issue:3 | Synthesis and in vitro antimicrobial activity of some novel substituted benzimidazole derivatives having potent activity against MRSA. |
| AID564827 | Antimicrobial activity against methicillin-resistant coagulase-negative Staphylococcus simulans assessed as resistant isolates after 24 hrs by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | In vitro activities of panduratin A against clinical Staphylococcus strains. |
| AID1209733 | Binding affinity to mouse OAT3 expressed in CHO cells at 10 to 1000 uM measured over 20 mins | 2013 | Drug metabolism and disposition: the biological fate of chemicals, Apr, Volume: 41, Issue:4 | Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics. |
| AID278552 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium longum ATCC 15707 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID554984 | Antibacterial activity against Acinetobacter genomosp. 3 isolate 14 by Etest method | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | Genetic variability among ampC genes from acinetobacter genomic species 3. |
| AID588460 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, Validation Compound Set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588460 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, Validation Compound Set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588460 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, Validation Compound Set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588461 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, Validation compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588461 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, Validation compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588461 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, Validation compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588459 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, Validation compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588459 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, Validation compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588459 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, Validation compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1347097 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347091 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347104 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for RD cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
| AID1347083 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1 | Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347100 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347095 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB-EBc1 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347089 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for TC32 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347094 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-37 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347086 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347407 | qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Pharmaceutical Collection | 2020 | ACS chemical biology, 07-17, Volume: 15, Issue:7 | High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle. |
| AID1347425 | Rhodamine-PBP qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46 | Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
| AID1347106 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for control Hh wild type fibroblast cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347424 | RapidFire Mass Spectrometry qHTS Assay for Modulators of WT P53-Induced Phosphatase 1 (WIP1) | 2019 | The Journal of biological chemistry, 11-15, Volume: 294, Issue:46 | Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4 | A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
| AID1347103 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347101 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for BT-12 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347093 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347102 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347099 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for NB1643 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347105 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347098 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347082 | qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal | 2020 | Antiviral research, 01, Volume: 173 | A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity. |
| AID1347107 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh30 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347096 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347108 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh41 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347090 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for DAOY cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID1347092 | qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells | 2018 | Oncotarget, Jan-12, Volume: 9, Issue:4 | Quantitative high-throughput phenotypic screening of pediatric cancer cell lines identifies multiple opportunities for drug repurposing. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5 | A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6 | A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| AID1803130 | Esterase Activity Assay from Article 10.3109/14756366.2011.604852: \\Effects of some drugs on human cord blood erythrocyte carbonic anhydrases I and II: an in vitro study.\\ | 2012 | Journal of enzyme inhibition and medicinal chemistry, Oct, Volume: 27, Issue:5 | Effects of some drugs on human cord blood erythrocyte carbonic anhydrases I and II: an in vitro study. |
| AID977611 | Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB | 2001 | Journal of molecular biology, Jun-08, Volume: 309, Issue:3 | Selection, characterization and x-ray structure of anti-ampicillin single-chain Fv fragments from phage-displayed murine antibody libraries. |
| AID1811 | Experimentally measured binding affinity data derived from PDB | 2001 | Journal of molecular biology, Jun-08, Volume: 309, Issue:3 | Selection, characterization and x-ray structure of anti-ampicillin single-chain Fv fragments from phage-displayed murine antibody libraries. |
| AID1224864 | HCS microscopy assay (F508del-CFTR) | 2016 | PloS one, , Volume: 11, Issue:10 | Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 8374 (60.76) | 18.7374 |
| 1990's | 1525 (11.07) | 18.2507 |
| 2000's | 1410 (10.23) | 29.6817 |
| 2010's | 1783 (12.94) | 24.3611 |
| 2020's | 690 (5.01) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.
| This Compound (110.93) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 1,251 (8.52%) | 5.53% |
| Reviews | 567 (3.86%) | 6.00% |
| Case Studies | 1,780 (12.12%) | 4.05% |
| Observational | 21 (0.14%) | 0.25% |
| Other | 11,066 (75.36%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antibiotic Prophylaxis for Early Ventilator-associated Pneumonia in Neurological Patients: A Randomized Trial [NCT01118403] | Phase 4 | 0 participants (Actual) | Interventional | 2011-03-31 | Withdrawn(stopped due to He could not be started due to lack of funds) | ||
| Operational Research on Management at First Level Facilities for Children With Severe Pneumonia [NCT01312792] | 300 participants (Actual) | Interventional | 2010-08-31 | Completed | |||
| A Multicenter, Randomized, Open-Label Comparison of the Safety And Efficacy of Tigecycline With That of Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Complicated Skin And Skin Structure Infections [NCT00368537] | Phase 4 | 550 participants (Actual) | Interventional | 2006-09-30 | Completed | ||
| NICU Antibiotics and Outcomes Trial [NCT03997266] | Phase 4 | 802 participants (Anticipated) | Interventional | 2020-08-05 | Recruiting | ||
| Population Pharmacokinetics of Anti-infective Drugs in Children in Anti-infectious Therapies [NCT03113344] | 800 participants (Anticipated) | Observational [Patient Registry] | 2017-06-21 | Recruiting | |||
| Prospective Randomized Study to Compare Clinical Outcomes in Patients With Osteomyelitis Treated With Intravenous Antibiotics Versus Intravenous Antibiotics With an Early Switch to Oral Antibiotics [NCT02099240] | Early Phase 1 | 11 participants (Actual) | Interventional | 2014-03-06 | Terminated(stopped due to Not enough patient enrollment and lack of staffing) | ||
| PK and PD Modeling of Ampicillin and Gentamicin in Peripartum Patients [NCT02427932] | 45 participants (Actual) | Observational | 2015-05-31 | Completed | |||
| A Randomized Controlled Trial Assessing Noninferiority of Three Antimicrobial Regimens for the Treatment of Grade III Open Fractures [NCT03560232] | Phase 4 | 17 participants (Actual) | Interventional | 2018-07-09 | Terminated(stopped due to Unable to recruit patients in a timely fashion and unable to recruit sufficient patients) | ||
| The Value of Amniopatch in Pregnancies Associated With Spontaneous Preterm Premature Rupture of Fetal Membranes:A Randomized Controlled Trial [NCT03473210] | 100 participants (Actual) | Interventional | 2016-10-01 | Completed | |||
| Ampicillin / Sulbactam Versus Cefuroxime as Antimicrobial Prophylaxis for Cesarean Section: a Randomized Study [NCT01138852] | Phase 4 | 176 participants (Actual) | Interventional | 2004-07-31 | Completed | ||
| Therapeutic Drug Monitoring and Continuous Infusion of Beta-lactam Antibiotics in Patients With Bacteraemia [NCT03108690] | Phase 4 | 0 participants (Actual) | Interventional | 2017-10-01 | Withdrawn(stopped due to Logistics) | ||
| Asymptomatic Bacteriuria & Risk of Urinary Tract Infection in Renal Transplants [NCT01349738] | 200 participants (Anticipated) | Observational | 2011-05-31 | Enrolling by invitation | |||
| Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL) [NCT05156437] | Phase 4 | 20 participants (Anticipated) | Interventional | 2022-03-16 | Enrolling by invitation | ||
| TREAT: Treatment of ppROM With Erythromycin vs. Azithromycin Trial [NCT03060473] | Phase 3 | 324 participants (Anticipated) | Interventional | 2017-02-23 | Recruiting | ||
| Is an Antibiotic Prescription Required After Laparoscopic Cholecystectomy for Acute Calculous Cholecystitis? [NCT04290104] | Phase 4 | 2 participants (Anticipated) | Interventional | 2020-10-15 | Not yet recruiting | ||
| Antibiotic Use in Facial Fracture Post Injury [NCT04925531] | 1,000 participants (Anticipated) | Observational [Patient Registry] | 2016-07-29 | Recruiting | |||
| The Endourology Disease Group for Excellence (EDGE) Consortium: A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Percutaneous Nephrolithotomy in Patients With Moderate Risk of Postoperative Infection [NCT02829060] | 330 participants (Anticipated) | Interventional | 2016-01-31 | Recruiting | |||
| Comparing Oral Versus Parenteral Antimicrobial Therapy (COPAT) Trial [NCT05977868] | Phase 4 | 135 participants (Anticipated) | Interventional | 2023-08-04 | Enrolling by invitation | ||
| Successful Treatment of Maternal Listeria Monocytogenes Bacteremia in the First Trimester of Pregnancy: a Case Report and Review of Literatures [NCT03248973] | 1 participants (Actual) | Observational | 2017-04-03 | Completed | |||
| NICU Antibiotics and Outcomes Follow-Up Study [NCT05977400] | Phase 3 | 802 participants (Anticipated) | Interventional | 2024-04-30 | Not yet recruiting | ||
| Cefiderocol and Ampicillin-sulbactam vs. Colistin or Colistin-meropenem for Carbapenem Resistant Acinetobacter Baumannii Bacteremia or Hospital-acquired Pneumonia: Controlled Clinical Study With Historical Controls (CASCADE) [NCT05922124] | Phase 4 | 734 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| A Comparative Study of Ampicillin/Sulbactam Versus Moxifloxacin in the Treatment of Complicated Intra-abdominal Infections [NCT00952796] | Phase 4 | 100 participants (Anticipated) | Interventional | 2009-01-31 | Completed | ||
| Comparison of Two Antibiotic Prophylactic Protocols in Preterm Premature Rupture of the Membranes. A Randomized Prospective, Open Trial [NCT02819570] | Phase 4 | 400 participants (Anticipated) | Interventional | 2015-11-30 | Recruiting | ||
| Antibiotic Effects on the Developing Microbiome, Metabolome and Morbidities in Preterm Neonates [NCT02784821] | Phase 2 | 186 participants (Actual) | Interventional | 2017-01-16 | Completed | ||
| Supportive Care and Antibiotics for Severe Pneumonia Among Hospitalized Children [NCT04041791] | Phase 3 | 4,392 participants (Anticipated) | Interventional | 2019-08-19 | Recruiting | ||
| Phase III Trial of Antibiotics to Reduce Chorioamnionitis-Related Perinatal HIV Transmission [NCT00021671] | Phase 3 | 3,720 participants | Interventional | Completed | |||
| A Prospective, Double-blind, Multi Center, Randomized Clinical Study to Compare the Efficacy and Safety of Ertapenem 3 Days Versus Ampicillin-Sulbactam 3 Days in the Treatment of Localized Community Acquired Intra-abdominal Infection (IAI). (T.E.A. Study [NCT00630513] | Phase 4 | 142 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| Different Azithromycin Protocols for Management of Preterm Pre-labor Rupture of Membranes [NCT04202380] | 300 participants (Anticipated) | Interventional | 2020-01-31 | Not yet recruiting | |||
| Treatment of Chorioamnionitis After Delivery [NCT00814905] | 300 participants (Anticipated) | Interventional | 2009-06-30 | Recruiting | |||
| A Multicenter, Unblinded, Non-Comparative Study Of Unasyn-S 12 G/Day Evaluating The Safety And Efficacy In Japanese Adult Subjects With Community Acquired Pneumonia [NCT01189487] | Phase 3 | 47 participants (Actual) | Interventional | 2010-10-31 | Completed | ||
| Effect of Lactobacillus Reuteri DSM17938 in Neonates Treated With Antibiotics on Emergence of Functional Gastrointestinal Disorders, Body Composition, Mineral Bone Density and Fecal Microbiota in Infancy [NCT02865564] | 98 participants (Actual) | Interventional | 2016-11-30 | Active, not recruiting | |||
| Randomized, Multicenter, Phase III, Controlled Clinical Trial, to Demonstrate the no Inferiority of Reduced Antibiotic Treatment vs a Broad Spectrum Betalactam Antipseudomonal Treatment in Patients With Bacteremia by Enterobacteriaceae [NCT02795949] | Phase 3 | 344 participants (Actual) | Interventional | 2016-10-31 | Completed | ||
| Ciprofloxacin, Ampicillin-sulbactam and Placebo Prophylaxis in Laparoscopic Cholecystectomy. A Randomized Controlled Study [NCT01888822] | Phase 4 | 138 participants (Actual) | Interventional | 2013-06-30 | Terminated | ||
| Multiple-dose Pharmacokinetics of Ampicillin / Sulbactam and Amoxicillin / Clavulanic Acid During Haemodialysis in Longterm Haemodialysis Patients [NCT02007603] | Phase 3 | 16 participants (Actual) | Interventional | 2013-08-31 | Completed | ||
| A Prospective, Randomized Trial of Antibiotic Duration in Post-appendectomy Abscess [NCT03795194] | Phase 4 | 12 participants (Actual) | Interventional | 2019-05-01 | Terminated(stopped due to Due to low enrollment.) | ||
| Prospective, Multi-center, Randomized, Non-blind Trial to Assess the Efficacy and Safety of Moxifloxacin Versus Sulbactam/Ampicillin in the Treatment of Pulmonary Abscess and Aspiration Pneumonia [NCT01045902] | Phase 3 | 139 participants (Actual) | Interventional | 2001-02-28 | Completed | ||
| Phase IV Study of Determining the Efficacy of Ampicillin/Sulbactam Combination as Antibiotic Prophylaxis During Breast Cancer Surgery in Patients With a Body Mass Index (BMI) Over 25. [NCT00356148] | Phase 4 | 372 participants (Actual) | Interventional | 2003-10-31 | Completed | ||
| Prophylactic Antibiotics for Manual Removal of Retained Placenta in Vaginal Birth [NCT01945450] | 300 participants (Anticipated) | Interventional | 2014-01-31 | Not yet recruiting | |||
| The Impact of Cefepime and Unictam on Preventing Post-Cesarean Surgical Site Infections [NCT06048692] | Phase 3 | 213 participants (Actual) | Interventional | 2023-01-01 | Active, not recruiting | ||
| Prospective Randomized Evaluation of Antibiotic Regimen Following Appendectomy for Perforated Appendicitis [NCT00195923] | 100 participants | Observational | 2005-04-30 | Completed | |||
| Prospective, Doubleblind, Randomized Multicenter Study to Proof the Clinical and Bacteriological Non-inferiority of Ampicillin/Amoxicillin Versus Moxifloxacin in Hospitalized Patients With Non-severe Community-acquired Pneumonia [NCT00887276] | Phase 4 | 290 participants (Actual) | Interventional | 2008-11-30 | Terminated | ||
| Comparing Obstetrical Outcomes and Infectious Morbidity Between Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor [NCT05469984] | 200 participants (Anticipated) | Interventional | 2022-09-30 | Not yet recruiting | |||
| Antimicrobial Pharmacokinetics in High Risk Infants (Urinary Proteomics in Antimicrobial/Antifungal-Treated Newborns - add-on Study) [NCT00491426] | 450 participants (Actual) | Observational | 2006-01-31 | Completed | |||
| Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy [NCT02579161] | Phase 3 | 98 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients [NCT00002052] | 0 participants | Interventional | Completed | ||||
| A Multicenter, Open Label Trial Evaluating Intravenous Azithromycin Plus Intravenous Ampicillin/Sulbactam Followed by Oral Azithromycin Plus Intravenous Ampicillin/Sulbactam for the Treatment of Hospitalized Subjects With Community-Acquired Pneumonia (CAP [NCT00137007] | Phase 4 | 151 participants (Actual) | Interventional | 2003-11-30 | Completed | ||
| Efficacy, Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days of Age (Inclusive) With Clinical or Confirmed Late-onset Sepsis : a European Multicenter Randomised Phase III Trial [NCT01551394] | Phase 3 | 272 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
| Clinical Implication of Next Generation Sequencing of Urinary Bacteria in Patients With Low Colony Forming Units of Bacteria in Traditional Urine Culture [NCT05206500] | Phase 4 | 100 participants (Anticipated) | Interventional | 2022-05-17 | Recruiting | ||
| Prospective, Observational Study of Clinical Outcomes Among Children 2 to 59 Months of Age With Childhood Pneumonia and Other Co-morbidities in Lilongwe, Malawi Who Have Been Excluded From Pneumonia Clinical Trials [NCT02960919] | 1,001 participants (Actual) | Observational | 2016-10-19 | Completed | |||
| Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term - a Randomized Controlled Trial [NCT01633294] | Phase 2/Phase 3 | 161 participants (Actual) | Interventional | 2008-10-31 | Completed | ||
| The Evaluation of Postoperative Antibiotics in Non-Infected Mandible Fractures [NCT04198129] | Phase 1 | 174 participants (Anticipated) | Interventional | 2020-10-01 | Recruiting | ||
| Antibiotic Safety in Infants With Complicated Intra-Abdominal Infections (SCAMP Trial) [NCT01994993] | Phase 2/Phase 3 | 260 participants (Actual) | Interventional | 2013-12-31 | Completed | ||
| A Pilot, Randomized, Double-Blind, Placebo-Controlled Phase I Study to Determine the Safety and Efficacy of Ampicillin in Treating Primary Dystonia Symptoms [NCT01433757] | Phase 1 | 2 participants (Actual) | Interventional | 2011-09-30 | Completed | ||
| A Phase 2/3, Randomized, Open-Label, Multi-center Study to Determine the Safety and Efficacy of Solithromycin in Adolescents and Children With Suspected or Confirmed Community-Acquired Bacterial Pneumonia [NCT02605122] | Phase 2/Phase 3 | 97 participants (Actual) | Interventional | 2016-04-30 | Terminated(stopped due to Development not proceeding) | ||
| A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome [NCT02477423] | 27 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| Antibiotic Profile of Pathogenic Bacteria Isolated From Postsurgical Site Infections in Public Hospitals in Northern Jordan [NCT05106803] | 24 participants (Actual) | Observational | 2019-08-01 | Completed | |||
| Efficacy of Preoperative Prophylactic Antibiotics in Preventing Complications in the Primary Repair of Cleft Palates [NCT00760006] | Phase 2 | 224 participants (Actual) | Interventional | 2008-05-31 | Completed | ||
| Comparison of Ampicillin / Sulbactam vs. Ampicillin / Gentamicin for Treatment of Intrapartum Chorioamnionitis: a Randomized Controlled Trial [NCT00879190] | Phase 2/Phase 3 | 92 participants (Actual) | Interventional | 2009-05-31 | Completed | ||
| Safety and Efficacy of Single Daily Dose of Ceftriaxone and Metronidazole for Treatment of Complicated Appendicitis in Children [NCT01678365] | Phase 4 | 43 participants (Actual) | Interventional | 2008-07-31 | Completed | ||
| Intravenous Versus Intravenous/Oral Antibiotics for Perforated Appendicitis [NCT00462020] | 102 participants (Actual) | Interventional | 2007-03-31 | Completed | |||
| Special Use-result Surveillance Of Unasyn-s (Kit) For Intravenous Use - A Surveillance On High-dose (>6 G Daily) Administration For Pneumonia, Lung Abscess And Peritonitis - [NCT01793688] | 982 participants (Actual) | Observational | 2013-03-12 | Completed | |||
| Open-label, Multicentre Study To Evaluate The Safety, Tolerability, Pharmacokinetics, And Efficacy Of Ceftaroline In Neonates And Young Infants With Late-onset Sepsis [NCT02424734] | Phase 2 | 11 participants (Actual) | Interventional | 2015-08-04 | Terminated(stopped due to Study was terminated on 22Dec2017 due to slow enrollment; there were no safety or efficacy concerns.) | ||
| A Randomized Trial to Investigate Strategies to Reduce Mortality Among HIV-infected and HIV-exposed Children Admitted With Severe Acute Malnutrition in Mulago Hospital, Kampala, Uganda [NCT05051163] | Phase 2/Phase 3 | 300 participants (Anticipated) | Interventional | 2021-06-14 | Recruiting | ||
| The EDGE Consortium: A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Percutaneous Nephrolithotomy: Part 1 [NCT02384200] | Phase 4 | 86 participants (Actual) | Interventional | 2015-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||