Page last updated: 2024-11-05

3-hydroxycarbofuran

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3-hydroxycarbofuran: main metabolite of carbofuran [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID27975
CHEMBL ID1867082
CHEBI ID174216
SCHEMBL ID3400466
MeSH IDM0091464

Synonyms (48)

Synonym
3-hydroxy-carbofuran
(3-hydroxy-2,2-dimethyl-3h-1-benzouran-7-yl) n-methylcarbamate
CHEBI:174216
carbamic acid, methyl-, 2,3-dihydro-2,2-dimethyl-3-hydroxy-7-benzofuranyl ester
ccris 9207
brn 1383873
3-hydroxycarbofuran
3,7-benzofurandiol, 2,3-dihydro-2,2-dimethyl-, 7-(methylcarbamate)
NCGC00163948-01
36550_riedel
16655-82-6
carbofuran-3-hydroxy
3,7-benzofurandiol, 2,3-dihydro-2,2-dimethyl- 7-(methylcarbamate)
3,7-benzofurandiol, 2,3-dihydro-2,2-dimethyl-, 7-(methylcarbamate) (9ci)
37896_riedel
FT-0669337
SCHEMBL3400466
(3-hydroxy-2,2-dimethyl-3h-1-benzofuran-7-yl) n-methylcarbamate
unii-7j7n7a61bj
7j7n7a61bj ,
5-17-05-00204 (beilstein handbook reference)
3-hydroxy carbofuran
AKOS022181449
RHSUJRQZTQNSLL-UHFFFAOYSA-N
3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate #
carbamic acid, methyl-, 2,3-dihydro-3-hydroxy-2,2-dimethyl-7-benzofuranyl ester
carbofuran, 3-hydroxy
carbofuran 3-oh
CHEMBL1867082
DTXSID2037506
3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl n-methylcarbamate
carbofuran-3-hydroxy, pestanal(r), analytical standard
carbofuran-3-hydroxy 100 microg/ml in ethyl acetate
2,3-dihydro-2,2-dimethyl-3,7-benzofurandiol 7-(methylcarbamate)
J-010297
pesticide3_3-hydroxycarbofuran_c12h15no4_3,7-benzofurandiol, 2,3-dihydro-2,2-dimethyl-, 7-(methylcarbamate)
3-hydroxycarbofuran; methylcarbamic acid
carbofuran-3-oh
3-oh-carbofuran
3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate
3-hydroxy-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl methylcarbamate
3-hydrocarbofuran
3-(2-oxo-propyl)-benzoicacidethylester
3,7-benzofurandiol, 2,3-dihydro-2,2-dimethyl-, 7-(n-methylcarbamate)
Q27268397
1ST20259
3-hydroxycarbofuran 100 microg/ml in acetonitrile
PD076405

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Therefore, a dosage of 420 g active ingredient per 100 kg seed was recommended, which could be considered as safe to human beings and animals."( Residues of carbosulfan and its metabolites carbofuran and 3-hydroxy carbofuran in rice field ecosystem in China.
He, HM; Hu, XQ; Wang, Q; Yu, JZ; Zhang, CP; Zhu, YH, 2016
)
0.43
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
1-benzofuransA member of the class of benzofurans consisting of a 1-benzofuran skeleton and its substituted derivatives thereof.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (3)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
farnesoid X nuclear receptorHomo sapiens (human)Potency0.00100.375827.485161.6524AID588527
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency0.01580.010039.53711,122.0200AID588545
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency54.48270.000627.21521,122.0200AID651741
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (24)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (16.67)18.7374
1990's2 (8.33)18.2507
2000's5 (20.83)29.6817
2010's9 (37.50)24.3611
2020's4 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 27.38

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index27.38 (24.57)
Research Supply Index3.33 (2.92)
Research Growth Index4.91 (4.65)
Search Engine Demand Index25.99 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (27.38)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (3.70%)6.00%
Case Studies2 (7.41%)4.05%
Observational0 (0.00%)0.25%
Other24 (88.89%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]